TB-Profiler result

Run: SRR13861397
Summary

Run ID: SRR13861397

Sample name:

Date: 03-04-2023 09:30:41

Number of reads: 684593

Percentage reads mapped: 22.84

Strain: lineage4.9

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.23 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.76 streptomycin
katG 2154798 c.1313_1314insT frameshift_variant 1.0 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5906 p.Val223Leu missense_variant 1.0
gyrB 6011 p.Val258Met missense_variant 1.0
gyrA 6307 c.-995T>G upstream_gene_variant 0.17
gyrA 6319 c.-983G>C upstream_gene_variant 0.17
gyrA 6325 c.-977C>G upstream_gene_variant 0.15
gyrB 6678 p.Pro480Arg missense_variant 0.96
gyrA 8453 c.1152A>C synonymous_variant 0.12
gyrA 8516 c.1215T>C synonymous_variant 0.15
gyrA 8519 c.1218A>C synonymous_variant 0.15
fgd1 490676 c.-107G>C upstream_gene_variant 1.0
fgd1 491043 c.261T>A synonymous_variant 0.15
fgd1 491049 c.267T>C synonymous_variant 0.19
fgd1 491063 p.Gly94Ala missense_variant 0.17
fgd1 491077 p.Asn99Gly missense_variant 0.21
fgd1 491082 c.300T>C synonymous_variant 0.22
fgd1 491083 p.Val101Ile missense_variant 0.22
fgd1 491091 c.309T>C synonymous_variant 0.28
fgd1 491094 c.312C>G synonymous_variant 0.28
fgd1 491106 c.324T>C synonymous_variant 0.28
fgd1 491121 c.339A>G synonymous_variant 0.25
fgd1 491137 p.Glu119Gln missense_variant 0.26
fgd1 491144 p.Ala121Glu missense_variant 0.26
fgd1 491166 c.384G>C synonymous_variant 0.25
fgd1 491181 c.399T>C synonymous_variant 0.27
fgd1 491191 p.Gly137Arg missense_variant 0.25
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.17
fgd1 491202 c.420G>C synonymous_variant 0.19
fgd1 491203 p.Gln141Glu missense_variant 0.19
fgd1 491212 p.Ser144Arg missense_variant 0.19
fgd1 491217 c.435T>C synonymous_variant 0.17
fgd1 491232 c.450T>C synonymous_variant 0.19
fgd1 491241 p.Asp153Glu missense_variant 0.18
fgd1 491244 c.462T>C synonymous_variant 0.18
fgd1 491259 c.477T>C synonymous_variant 0.18
fgd1 491286 c.504G>C synonymous_variant 0.16
fgd1 491292 c.510G>C synonymous_variant 0.17
fgd1 491295 c.513C>G synonymous_variant 0.17
fgd1 491296 p.Val172Ile missense_variant 0.17
fgd1 491301 c.519C>T synonymous_variant 0.17
ccsA 620028 c.138G>C synonymous_variant 1.0
rpoB 759638 c.-169T>A upstream_gene_variant 1.0
rpoB 760235 c.429T>C synonymous_variant 0.15
rpoB 760283 c.477G>C synonymous_variant 0.16
rpoB 760307 c.501T>C synonymous_variant 0.17
rpoB 760328 c.522G>C synonymous_variant 0.19
rpoB 760331 c.525G>C synonymous_variant 0.2
rpoB 760337 c.531C>G synonymous_variant 0.22
rpoB 760340 c.534G>C synonymous_variant 0.22
rpoB 760361 c.555T>C synonymous_variant 0.22
rpoB 760376 p.Asp190Glu missense_variant 0.22
rpoB 760406 c.600G>C synonymous_variant 0.19
rpoB 760418 c.612G>C synonymous_variant 0.19
rpoB 760424 c.618C>G synonymous_variant 0.16
rpoB 760454 c.650delG frameshift_variant 0.84
rpoB 760475 c.669A>G synonymous_variant 0.15
rpoB 760481 c.675G>C synonymous_variant 0.16
rpoB 760484 c.678A>G synonymous_variant 0.15
rpoB 760522 p.Ser239Asn missense_variant 0.14
rpoB 760591 p.Val262Ala missense_variant 0.21
rpoB 760611 c.805T>C synonymous_variant 0.19
rpoB 760634 c.828T>C synonymous_variant 0.16
rpoB 760646 c.840C>G synonymous_variant 0.15
rpoB 760655 c.849A>G synonymous_variant 0.16
rpoB 760661 c.855A>C synonymous_variant 0.16
rpoB 760670 c.864G>C synonymous_variant 0.17
rpoB 760674 c.868T>C synonymous_variant 0.18
rpoB 760679 c.873A>G synonymous_variant 0.18
rpoB 760683 c.877T>C synonymous_variant 0.18
rpoB 760718 c.912C>G synonymous_variant 0.16
rpoB 760721 c.915C>G synonymous_variant 0.16
rpoB 760724 c.918T>C synonymous_variant 0.17
rpoB 760730 c.924T>C synonymous_variant 0.17
rpoB 761255 c.1449T>G synonymous_variant 0.14
rpoB 761261 c.1455G>T synonymous_variant 0.14
rpoB 761327 c.1521A>G synonymous_variant 0.21
rpoB 761360 c.1554T>C synonymous_variant 0.13
rpoB 761362 p.Ser519Thr missense_variant 0.13
rpoB 761373 p.Val523His missense_variant 0.17
rpoB 761414 c.1608A>G synonymous_variant 0.18
rpoB 761423 c.1617T>C synonymous_variant 0.14
rpoB 761435 c.1629T>C synonymous_variant 0.12
rpoB 761437 p.Ala544Glu missense_variant 0.12
rpoB 761441 p.Asp545Glu missense_variant 0.12
rpoB 761452 p.Val549Ala missense_variant 0.13
rpoB 761459 c.1653G>C synonymous_variant 0.12
rpoB 762014 c.2208C>T synonymous_variant 0.13
rpoB 762027 c.2221_2223delCTCinsTTG synonymous_variant 0.14
rpoB 762032 c.2226C>G synonymous_variant 0.14
rpoB 762035 c.2229G>C synonymous_variant 0.14
rpoB 762053 c.2247T>C synonymous_variant 0.17
rpoB 762062 c.2256T>C synonymous_variant 0.17
rpoB 762065 c.2259T>C synonymous_variant 0.17
rpoB 762086 c.2280G>C synonymous_variant 0.14
rpoB 762101 c.2295C>G synonymous_variant 0.13
rpoB 762114 p.Ile770Val missense_variant 0.13
rpoB 762131 c.2325C>G synonymous_variant 0.16
rpoB 762143 c.2337T>C synonymous_variant 0.17
rpoB 762149 c.2343G>C synonymous_variant 0.14
rpoB 762167 c.2361T>C synonymous_variant 0.17
rpoB 762176 c.2370T>C synonymous_variant 0.21
rpoB 762185 c.2379G>C synonymous_variant 0.21
rpoB 762218 c.2412T>G synonymous_variant 0.27
rpoB 762254 c.2448T>C synonymous_variant 0.21
rpoB 762266 c.2460T>C synonymous_variant 0.2
rpoB 762284 c.2478G>C synonymous_variant 0.17
rpoB 762293 c.2487T>C synonymous_variant 0.17
rpoC 764161 c.792G>C synonymous_variant 0.13
rpoC 764188 c.819A>G synonymous_variant 0.19
rpoC 764195 p.Ser276Gln missense_variant 0.15
rpoC 764203 c.834G>T synonymous_variant 0.15
rpoC 764206 c.837T>C synonymous_variant 0.14
rpoC 764266 c.897T>C synonymous_variant 0.13
rpoC 765487 p.Met706Ile missense_variant 1.0
rpoC 766327 c.2958C>G synonymous_variant 0.15
rpoC 766345 c.2976T>C synonymous_variant 0.16
rpoC 766348 c.2979A>G synonymous_variant 0.15
rpoC 766363 c.2994G>C synonymous_variant 0.15
rpoC 766381 c.3012C>T synonymous_variant 0.14
rpoC 766384 c.3015A>G synonymous_variant 0.17
rpoC 766390 c.3021C>T synonymous_variant 0.17
rpoC 766408 c.3039C>T synonymous_variant 0.13
rpoC 766426 c.3057C>T synonymous_variant 0.14
rpoC 766447 c.3078T>C synonymous_variant 0.13
rpoC 766483 c.3114G>C synonymous_variant 0.13
rpoC 766484 p.Val1039Ile missense_variant 0.13
rpoC 766492 c.3123T>C synonymous_variant 0.16
rpoC 766495 c.3126C>T synonymous_variant 0.15
rpoC 766522 c.3153C>G synonymous_variant 0.18
rpoC 766528 c.3159T>C synonymous_variant 0.19
rpoC 766531 c.3162G>T synonymous_variant 0.19
rpoC 766543 c.3174C>T synonymous_variant 0.16
rpoC 766549 c.3180G>C synonymous_variant 0.16
rpoC 766573 c.3204T>C synonymous_variant 0.15
rpoC 766583 p.Gly1072Ser missense_variant 0.16
rpoC 766588 c.3219G>A synonymous_variant 0.13
rpoC 766609 p.Ile1080Met missense_variant 0.15
rpoC 767014 c.3645G>C synonymous_variant 0.12
rpoC 767033 p.Ser1222Thr missense_variant 0.12
rpoC 767074 c.3705T>C synonymous_variant 0.15
rpoC 767098 c.3729T>C synonymous_variant 0.19
rpoC 767119 c.3750A>G synonymous_variant 0.18
rpoC 767134 c.3765C>G synonymous_variant 0.14
rpoC 767158 c.3789T>C synonymous_variant 0.14
rpoC 767167 c.3798C>G synonymous_variant 0.14
rpoC 767180 p.Ala1271Gln missense_variant 0.14
mmpL5 775864 p.Ala873Ser missense_variant 0.14
mmpL5 775865 c.2616T>G synonymous_variant 0.19
mmpL5 775904 c.2577G>A synonymous_variant 0.13
mmpL5 775909 p.Leu858Phe missense_variant 0.14
mmpL5 775912 c.2569C>A synonymous_variant 0.13
mmpL5 775916 c.2565T>G synonymous_variant 0.14
mmpL5 775937 c.2544G>C synonymous_variant 0.14
rpsL 781409 c.-151T>A upstream_gene_variant 1.0
rpsL 781841 c.282C>G synonymous_variant 0.13
rplC 800612 c.-197A>G upstream_gene_variant 0.24
rplC 800618 c.-191T>C upstream_gene_variant 0.24
rplC 800648 c.-161A>C upstream_gene_variant 0.29
rplC 800654 c.-155T>C upstream_gene_variant 0.23
rplC 800693 c.-116A>G upstream_gene_variant 0.21
rplC 800703 c.-106T>C upstream_gene_variant 0.27
rplC 800715 c.-94A>C upstream_gene_variant 0.22
rplC 800720 c.-89T>C upstream_gene_variant 0.23
rplC 800723 c.-86C>G upstream_gene_variant 0.22
rplC 800738 c.-71T>C upstream_gene_variant 0.22
rplC 800747 c.-62C>G upstream_gene_variant 0.24
rplC 800771 c.-38C>T upstream_gene_variant 0.25
rplC 800814 c.6A>G synonymous_variant 0.25
rplC 800817 c.9A>T synonymous_variant 0.23
rplC 800844 c.36T>C synonymous_variant 0.29
rplC 800865 c.57A>G synonymous_variant 0.12
rplC 800867 p.Ser20Asn missense_variant 0.12
rplC 800889 c.81C>G synonymous_variant 0.17
fbiC 1302873 c.-58A>T upstream_gene_variant 1.0
fbiC 1303575 c.645G>C synonymous_variant 0.2
fbiC 1303584 c.654C>G synonymous_variant 0.2
fbiC 1303590 c.660A>G synonymous_variant 0.2
fbiC 1303602 c.672A>G synonymous_variant 0.16
fbiC 1303605 c.675C>G synonymous_variant 0.15
fbiC 1303608 c.678G>A synonymous_variant 0.15
fbiC 1303611 c.681G>C synonymous_variant 0.15
fbiC 1303614 c.684C>T synonymous_variant 0.15
fbiC 1303617 c.687C>G synonymous_variant 0.15
fbiC 1303632 c.702T>G synonymous_variant 0.14
fbiC 1303638 c.708A>G synonymous_variant 0.14
fbiC 1303674 c.744C>G synonymous_variant 0.16
fbiC 1303686 c.756C>G synonymous_variant 0.19
fbiC 1303695 c.765T>C synonymous_variant 0.19
fbiC 1303708 c.778T>C synonymous_variant 0.19
fbiC 1303728 c.798G>A synonymous_variant 0.13
fbiC 1303730 p.Leu267Pro missense_variant 0.13
fbiC 1303737 c.807G>A synonymous_variant 0.13
fbiC 1305231 c.2301C>G synonymous_variant 0.12
fbiC 1305237 c.2307A>G synonymous_variant 0.12
fbiC 1305240 c.2310T>C synonymous_variant 0.12
fbiC 1305244 c.2314T>C synonymous_variant 0.12
rrs 1471874 n.29A>C non_coding_transcript_exon_variant 0.96
rrs 1472101 n.256G>A non_coding_transcript_exon_variant 0.23
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.23
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.41
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.58
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.59
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.65
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.65
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.65
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.66
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.66
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.65
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.63
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.63
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.62
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.63
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.61
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.61
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.6
rrs 1472230 n.385C>T non_coding_transcript_exon_variant 0.23
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.62
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.62
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.61
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.52
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.47
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.34
rrs 1472262 n.417C>T non_coding_transcript_exon_variant 0.38
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.33
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.67
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.66
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.67
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.67
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.67
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.66
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.65
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.64
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.64
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.65
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.65
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.66
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.64
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.63
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.71
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.74
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.79
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.77
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.73
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.73
rrs 1472669 n.824_825insTAGG non_coding_transcript_exon_variant 0.75
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.73
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.72
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.74
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.74
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.77
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.77
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.51
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.28
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.26
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.26
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.26
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.27
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.27
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.27
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.26
rrs 1473281 n.1436C>A non_coding_transcript_exon_variant 0.25
rrs 1473282 n.1437C>G non_coding_transcript_exon_variant 0.24
rrs 1473288 n.1443C>A non_coding_transcript_exon_variant 0.26
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.3
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.25
rrs 1473296 n.1451G>C non_coding_transcript_exon_variant 0.26
rrs 1473297 n.1452G>T non_coding_transcript_exon_variant 0.28
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.29
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.27
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.27
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.31
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.21
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.17
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.18
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.15
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.15
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.17
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.18
rrl 1474051 n.394T>C non_coding_transcript_exon_variant 0.17
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.14
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.17
rrl 1474104 n.447G>A non_coding_transcript_exon_variant 0.16
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.18
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.15
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.16
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.17
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.16
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.12
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.12
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.12
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.12
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.29
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.77
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.81
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.88
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.89
rrl 1476263 n.2606C>T non_coding_transcript_exon_variant 0.17
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.88
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.86
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.87
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.86
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.87
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.87
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.86
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.86
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.85
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.85
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.85
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.86
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.86
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.86
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.93
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.96
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.96
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.95
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.95
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.94
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.73
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.94
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.94
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.94
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.94
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.93
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.91
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.85
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.79
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.77
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.78
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.78
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.78
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.78
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.78
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.79
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.79
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.78
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.78
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.73
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.74
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.73
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.68
rrl 1476595 n.2938C>G non_coding_transcript_exon_variant 0.16
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.13
inhA 1674756 c.555T>C synonymous_variant 0.15
inhA 1674771 c.570C>G synonymous_variant 0.14
inhA 1674774 c.573A>G synonymous_variant 0.14
inhA 1674780 c.579T>G synonymous_variant 0.18
inhA 1674786 c.585G>C synonymous_variant 0.15
inhA 1674799 p.Ser200Ala missense_variant 0.14
inhA 1674803 p.Ala201Gly missense_variant 0.13
inhA 1674816 c.615T>C synonymous_variant 0.14
inhA 1674818 p.Ala206Val missense_variant 0.13
rpsA 1833811 c.270G>C synonymous_variant 0.14
rpsA 1833838 c.297G>C synonymous_variant 0.14
rpsA 1833841 c.300C>G synonymous_variant 0.14
rpsA 1833847 c.306C>G synonymous_variant 0.14
rpsA 1833874 c.333T>C synonymous_variant 0.17
rpsA 1833940 c.399C>G synonymous_variant 0.2
rpsA 1833979 c.438T>C synonymous_variant 0.14
rpsA 1834000 c.459G>C synonymous_variant 0.17
rpsA 1834015 c.474G>C synonymous_variant 0.17
rpsA 1834021 c.480C>T synonymous_variant 0.14
ndh 2102559 p.Ser162Arg missense_variant 0.17
ndh 2102566 c.477A>G synonymous_variant 0.17
ndh 2102572 c.471A>G synonymous_variant 0.18
ndh 2102575 c.468G>A synonymous_variant 0.18
ndh 2102581 c.462T>G synonymous_variant 0.17
ndh 2102589 c.454T>C synonymous_variant 0.17
ndh 2102590 c.453A>C synonymous_variant 0.16
ndh 2102593 c.450C>G synonymous_variant 0.15
ndh 2102596 c.447C>G synonymous_variant 0.15
ndh 2102599 c.444T>C synonymous_variant 0.15
ndh 2102604 p.Leu147Val missense_variant 0.15
ndh 2102608 c.433_435delTTGinsCTC synonymous_variant 0.17
ndh 2102635 c.408C>G synonymous_variant 0.14
ndh 2102638 c.405A>G synonymous_variant 0.13
katG 2154654 p.Ser486Arg missense_variant 1.0
katG 2154882 c.1230G>A synonymous_variant 1.0
katG 2155857 c.255C>A synonymous_variant 1.0
PPE35 2170198 p.Ala139Ser missense_variant 1.0
pncA 2290069 c.-828C>T upstream_gene_variant 1.0
kasA 2518714 c.600A>C synonymous_variant 0.14
kasA 2518717 c.603C>T synonymous_variant 0.14
kasA 2518723 p.Glu203Asp missense_variant 0.14
kasA 2518732 c.618C>G synonymous_variant 0.14
eis 2714922 c.411G>A synonymous_variant 1.0
thyA 3074067 c.405C>G synonymous_variant 0.96
alr 3840223 c.1198A>C synonymous_variant 0.96
alr 3840711 p.Ser237Leu missense_variant 1.0
rpoA 3877953 c.555G>A synonymous_variant 0.16
rpoA 3877962 c.546G>T synonymous_variant 0.13
rpoA 3877986 c.522G>C synonymous_variant 0.14
rpoA 3877989 c.519A>G synonymous_variant 0.18
rpoA 3878001 c.507A>G synonymous_variant 0.21
rpoA 3878031 c.477T>C synonymous_variant 0.13
rpoA 3878040 c.468T>C synonymous_variant 0.17
rpoA 3878046 c.462T>C synonymous_variant 0.16
rpoA 3878049 c.459G>C synonymous_variant 0.17
rpoA 3878055 c.453A>G synonymous_variant 0.18
rpoA 3878061 c.447G>C synonymous_variant 0.19
rpoA 3878067 c.441C>G synonymous_variant 0.19
rpoA 3878070 c.438T>C synonymous_variant 0.19
rpoA 3878082 c.426T>C synonymous_variant 0.24
rpoA 3878094 c.414C>G synonymous_variant 0.15
rpoA 3878100 c.408C>G synonymous_variant 0.15
rpoA 3878103 c.405A>G synonymous_variant 0.14
rpoA 3878106 c.402G>C synonymous_variant 0.14
rpoA 3878118 c.390T>C synonymous_variant 0.23
rpoA 3878141 p.Met123Leu missense_variant 0.17
rpoA 3878142 p.Gly122Glu missense_variant 0.17
rpoA 3878169 c.339G>C synonymous_variant 0.15
rpoA 3878184 c.324C>T synonymous_variant 0.18
rpoA 3878187 c.321C>G synonymous_variant 0.17
rpoA 3878193 c.315T>C synonymous_variant 0.17
rpoA 3878199 c.309T>C synonymous_variant 0.17
rpoA 3878202 c.306G>C synonymous_variant 0.17
rpoA 3878217 c.291A>G synonymous_variant 0.16
rpoA 3878220 c.288C>T synonymous_variant 0.2
clpC1 4038398 c.2307G>T synonymous_variant 0.12
clpC1 4038419 c.2286T>C synonymous_variant 0.14
clpC1 4038989 c.1716T>C synonymous_variant 0.17
clpC1 4039073 c.1632C>G synonymous_variant 0.17
clpC1 4039085 c.1620A>G synonymous_variant 0.18
clpC1 4039090 c.1615C>T synonymous_variant 0.18
clpC1 4039097 c.1608G>C synonymous_variant 0.16
clpC1 4039103 c.1602T>C synonymous_variant 0.17
clpC1 4039106 c.1599G>C synonymous_variant 0.17
clpC1 4039112 c.1593C>G synonymous_variant 0.17
clpC1 4039121 c.1584T>C synonymous_variant 0.18
clpC1 4039124 c.1581C>G synonymous_variant 0.18
clpC1 4039142 c.1563A>G synonymous_variant 0.17
clpC1 4039145 c.1560G>C synonymous_variant 0.18
clpC1 4039169 p.Glu512Asp missense_variant 0.17
clpC1 4039172 c.1533A>G synonymous_variant 0.17
clpC1 4039178 c.1527G>C synonymous_variant 0.17
clpC1 4039183 c.1522T>C synonymous_variant 0.17
clpC1 4039187 c.1518G>C synonymous_variant 0.14
clpC1 4039190 c.1515C>G synonymous_variant 0.15
clpC1 4039208 c.1497C>G synonymous_variant 0.14
clpC1 4039226 c.1479T>C synonymous_variant 0.15
clpC1 4039268 c.1437C>G synonymous_variant 0.18
clpC1 4039274 c.1431G>C synonymous_variant 0.22
clpC1 4039286 c.1419T>C synonymous_variant 0.23
clpC1 4039289 c.1416T>C synonymous_variant 0.14
clpC1 4039295 c.1410A>C synonymous_variant 0.15
clpC1 4039319 c.1386T>C synonymous_variant 0.17
clpC1 4039322 c.1383T>C synonymous_variant 0.17
clpC1 4039328 c.1377A>G synonymous_variant 0.16
clpC1 4039334 c.1371G>C synonymous_variant 0.16
clpC1 4039337 p.Thr456Gln missense_variant 0.16
clpC1 4039388 c.1317C>A synonymous_variant 0.18
clpC1 4039391 c.1314T>G synonymous_variant 0.18
clpC1 4039409 c.1296T>C synonymous_variant 0.17
clpC1 4039412 c.1293T>G synonymous_variant 0.17
clpC1 4039430 c.1275T>C synonymous_variant 0.12
clpC1 4039648 p.Glu353Gln missense_variant 1.0
clpC1 4040168 c.537G>C synonymous_variant 0.15
clpC1 4040201 c.504C>G synonymous_variant 0.14
clpC1 4040213 c.490_492delTCTinsAGC synonymous_variant 0.14
clpC1 4040225 c.480A>C synonymous_variant 0.15
clpC1 4040228 c.477G>C synonymous_variant 0.15
clpC1 4040234 c.471C>G synonymous_variant 0.17
clpC1 4040237 c.468C>T synonymous_variant 0.16
clpC1 4040249 c.456A>G synonymous_variant 0.16
clpC1 4040273 c.432T>C synonymous_variant 0.16
clpC1 4040354 c.351A>G synonymous_variant 0.2
clpC1 4040363 c.342A>C synonymous_variant 0.18
clpC1 4040369 c.336C>G synonymous_variant 0.18
clpC1 4040380 c.325T>C synonymous_variant 0.19
clpC1 4040381 c.324T>C synonymous_variant 0.19
clpC1 4040387 c.318A>G synonymous_variant 0.2
clpC1 4040393 c.312G>C synonymous_variant 0.22
clpC1 4040411 c.294T>C synonymous_variant 0.21
clpC1 4040423 c.282A>G synonymous_variant 0.17
clpC1 4040426 c.279T>C synonymous_variant 0.17
clpC1 4040441 c.264C>G synonymous_variant 0.14
clpC1 4040444 c.261C>G synonymous_variant 0.14
clpC1 4040459 c.246C>G synonymous_variant 0.14
clpC1 4040465 c.240T>C synonymous_variant 0.16
embC 4242023 p.Val721Leu missense_variant 1.0
embA 4245071 c.1839G>A synonymous_variant 0.89
embB 4248070 c.1557T>C synonymous_variant 0.14
embB 4248085 c.1572T>C synonymous_variant 0.15
embB 4248097 c.1584C>G synonymous_variant 0.16
embB 4248142 c.1629T>C synonymous_variant 0.14
embB 4248143 c.1630T>C synonymous_variant 0.14
embB 4248206 p.Ser565Gly missense_variant 0.17
embB 4248220 c.1707A>G synonymous_variant 0.19
embB 4248241 c.1728C>T synonymous_variant 0.17
embB 4248265 c.1752C>T synonymous_variant 0.18
embB 4248266 c.1753C>T synonymous_variant 0.18
embB 4248277 c.1764G>C synonymous_variant 0.2
embB 4248304 c.1791G>T synonymous_variant 0.17
ethA 4327364 p.Lys37Arg missense_variant 1.0