TB-Profiler result

Run: SRR13861447
Summary

Run ID: SRR13861447

Sample name:

Date: 03-04-2023 09:31:59

Number of reads: 646869

Percentage reads mapped: 10.79

Strain: lineage4.9

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761135 p.Leu443Phe missense_variant 0.15 rifampicin
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.15 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.84 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7541 c.240C>G synonymous_variant 0.13
gyrA 7637 c.336C>G synonymous_variant 0.13
gyrA 7730 p.Arg143Ser missense_variant 0.14
gyrA 7877 p.His192Gln missense_variant 0.94
gyrA 8852 c.1551T>C synonymous_variant 0.14
gyrA 8858 c.1557T>C synonymous_variant 0.16
gyrA 8867 c.1566A>G synonymous_variant 0.14
gyrA 8870 c.1569G>C synonymous_variant 0.14
gyrA 8873 c.1572A>C synonymous_variant 0.14
gyrA 8897 c.1596T>C synonymous_variant 0.16
gyrA 8915 c.1614A>G synonymous_variant 0.18
gyrA 8942 c.1641G>C synonymous_variant 0.12
mshA 576146 p.Val267Leu missense_variant 1.0
ccsA 620703 c.813G>C synonymous_variant 0.15
ccsA 620710 p.Val274Met missense_variant 0.15
ccsA 620734 c.844C>A synonymous_variant 0.14
ccsA 620739 c.849A>G synonymous_variant 0.14
ccsA 620745 c.855G>C synonymous_variant 0.14
ccsA 620748 c.858T>A synonymous_variant 0.14
ccsA 620778 c.888T>C synonymous_variant 0.17
ccsA 620784 c.894C>G synonymous_variant 0.17
ccsA 620787 c.897C>G synonymous_variant 0.17
rpoB 759647 c.-160T>C upstream_gene_variant 0.14
rpoB 759659 c.-148_-147insGA upstream_gene_variant 0.15
rpoB 759662 c.-145C>T upstream_gene_variant 0.15
rpoB 759683 c.-124T>C upstream_gene_variant 0.14
rpoB 759869 c.63C>T synonymous_variant 1.0
rpoB 760514 c.708C>T synonymous_variant 0.15
rpoB 760522 p.Ser239Asn missense_variant 0.16
rpoB 760934 c.1128C>T synonymous_variant 0.13
rpoB 760970 c.1164G>C synonymous_variant 0.14
rpoB 760982 c.1176G>C synonymous_variant 0.13
rpoB 760991 c.1185G>C synonymous_variant 0.14
rpoB 761015 c.1209G>C synonymous_variant 0.2
rpoB 761021 c.1215G>C synonymous_variant 0.23
rpoB 761027 c.1221A>G synonymous_variant 0.22
rpoB 761036 c.1230G>C synonymous_variant 0.21
rpoB 761037 c.1231T>C synonymous_variant 0.21
rpoB 761051 c.1245G>T synonymous_variant 0.15
rpoB 761054 c.1248G>C synonymous_variant 0.14
rpoB 761057 c.1251G>C synonymous_variant 0.14
rpoB 761060 c.1254C>G synonymous_variant 0.16
rpoB 761063 c.1257C>G synonymous_variant 0.17
rpoB 761094 c.1288C>T synonymous_variant 0.16
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.15
rpoB 761102 c.1296A>G synonymous_variant 0.15
rpoB 761150 c.1344A>C synonymous_variant 0.14
rpoC 763136 c.-234C>T upstream_gene_variant 0.15
rpoC 763148 c.-222G>C upstream_gene_variant 0.16
rpoC 763158 c.-212C>T upstream_gene_variant 0.17
rpoC 763782 p.Ser138* stop_gained 1.0
rpoC 764568 p.Lys400Thr missense_variant 0.95
rpoC 765412 c.2043T>C synonymous_variant 0.14
rpoC 765421 c.2052C>G synonymous_variant 0.14
rpoC 765451 c.2082C>G synonymous_variant 0.16
rpoC 765452 p.Ala695Ser missense_variant 0.16
rpoC 765478 c.2109T>C synonymous_variant 0.24
rpoC 765499 c.2130C>G synonymous_variant 0.18
rpoC 765508 c.2139C>G synonymous_variant 0.19
rpoC 765559 c.2190G>C synonymous_variant 0.14
rpoC 765578 c.2209C>T synonymous_variant 0.14
rpoC 765583 c.2214G>T synonymous_variant 0.16
rpoC 766384 c.3015A>G synonymous_variant 0.15
rpoC 766390 c.3021C>T synonymous_variant 0.14
rpoC 766408 c.3039C>T synonymous_variant 0.14
rpoC 766426 c.3057C>T synonymous_variant 0.22
rpoC 766447 c.3078T>C synonymous_variant 0.17
rpoC 766483 c.3114G>C synonymous_variant 0.17
rpoC 766484 p.Val1039Ile missense_variant 0.17
rpoC 766492 c.3123T>C synonymous_variant 0.17
rpoC 766495 c.3126C>T synonymous_variant 0.17
rpoC 766522 c.3153C>G synonymous_variant 0.16
rpoC 766528 c.3159T>C synonymous_variant 0.19
rpoC 766531 c.3162G>T synonymous_variant 0.19
rpoC 766543 c.3174C>T synonymous_variant 0.16
rpoC 766549 c.3180G>C synonymous_variant 0.16
mmpL5 777073 p.Lys470Glu missense_variant 1.0
mmpL5 777311 c.1170C>T synonymous_variant 1.0
mmpL5 778981 c.-501C>A upstream_gene_variant 0.95
rpsL 781736 c.177T>C synonymous_variant 0.15
rpsL 781832 c.273T>C synonymous_variant 0.17
rpsL 781841 c.282C>G synonymous_variant 0.18
rpsL 781859 c.300T>C synonymous_variant 0.18
rpsL 781898 c.339A>T synonymous_variant 0.15
rplC 800612 c.-197A>G upstream_gene_variant 0.23
rplC 800618 c.-191T>C upstream_gene_variant 0.23
rplC 800648 c.-161A>C upstream_gene_variant 0.25
rplC 800654 c.-155T>C upstream_gene_variant 0.24
rplC 800693 c.-116A>G upstream_gene_variant 0.13
rplC 800703 c.-106T>C upstream_gene_variant 0.16
rplC 800715 c.-94A>C upstream_gene_variant 0.16
rplC 800720 c.-89T>C upstream_gene_variant 0.16
rplC 800723 c.-86C>G upstream_gene_variant 0.17
rplC 800738 c.-71T>C upstream_gene_variant 0.15
rplC 800771 c.-38C>T upstream_gene_variant 0.14
rplC 801436 p.Ser210Arg missense_variant 0.97
fbiC 1303686 c.756C>G synonymous_variant 1.0
fbiC 1304634 c.1704C>G synonymous_variant 0.12
fbiC 1304691 c.1761G>C synonymous_variant 0.18
fbiC 1304694 c.1764A>C synonymous_variant 0.18
fbiC 1304703 c.1773C>G synonymous_variant 0.19
fbiC 1304715 c.1785G>C synonymous_variant 0.19
fbiC 1304757 c.1827A>G synonymous_variant 0.12
fbiC 1304808 c.1878C>G synonymous_variant 0.17
fbiC 1304811 c.1881C>G synonymous_variant 0.17
fbiC 1305297 c.2367G>C synonymous_variant 0.13
fbiC 1305303 c.2373T>C synonymous_variant 0.13
fbiC 1305311 p.Arg794Gln missense_variant 0.13
fbiC 1305331 p.Glu801Lys missense_variant 0.19
fbiC 1305336 c.2406T>C synonymous_variant 0.12
fbiC 1305381 c.2451G>C synonymous_variant 0.13
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.18
rrs 1472101 n.256G>A non_coding_transcript_exon_variant 0.36
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.35
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.58
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.7
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.51
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.74
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.74
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.75
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.74
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.74
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.75
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.76
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.77
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.75
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.76
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.77
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.76
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.76
rrs 1472230 n.385C>T non_coding_transcript_exon_variant 0.18
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.75
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.75
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.73
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.64
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.62
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.52
rrs 1472262 n.417C>T non_coding_transcript_exon_variant 0.49
rrs 1472269 n.424G>A non_coding_transcript_exon_variant 0.28
rrs 1472271 n.426T>C non_coding_transcript_exon_variant 0.29
rrs 1472277 n.432C>A non_coding_transcript_exon_variant 0.18
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.29
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.57
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.83
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.83
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.85
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.85
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.84
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.84
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.84
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.84
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.84
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.84
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.84
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.83
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.85
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.85
rrs 1472605 n.760G>C non_coding_transcript_exon_variant 0.15
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.89
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.9
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.9
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.88
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.87
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.87
rrs 1472669 n.824_825insTAGG non_coding_transcript_exon_variant 0.88
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.86
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.86
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.85
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.85
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.84
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.85
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.66
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.52
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.48
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.48
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.5
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.48
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.5
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.51
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.51
rrs 1473281 n.1436C>A non_coding_transcript_exon_variant 0.52
rrs 1473282 n.1437C>G non_coding_transcript_exon_variant 0.52
rrs 1473288 n.1443C>A non_coding_transcript_exon_variant 0.53
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.56
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.53
rrs 1473296 n.1451G>C non_coding_transcript_exon_variant 0.53
rrs 1473297 n.1452G>T non_coding_transcript_exon_variant 0.53
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.53
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.6
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.59
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.57
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.17
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.17
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.23
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.8
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.84
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.88
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.89
rrl 1476263 n.2606C>T non_coding_transcript_exon_variant 0.19
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.89
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.89
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.88
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.89
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.9
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.9
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.91
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.91
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.91
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.9
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.9
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.91
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.91
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.91
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.95
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.97
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.97
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.97
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.97
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.96
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.77
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.96
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.96
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.96
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.96
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.97
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.95
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.92
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.9
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.87
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.87
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.89
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.89
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.89
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.89
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.89
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.89
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.89
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.87
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.85
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.86
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.86
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.86
rrl 1476595 n.2938C>G non_coding_transcript_exon_variant 0.17
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.21
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.23
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.27
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.14
inhA 1674376 p.Pro59Ser missense_variant 0.95
rpsA 1833619 c.78A>C synonymous_variant 0.14
tlyA 1917844 c.-96C>A upstream_gene_variant 0.96
tlyA 1918260 p.His107Gln missense_variant 1.0
katG 2154461 p.Ala551Pro missense_variant 1.0
Rv1979c 2222535 c.630C>G synonymous_variant 1.0
kasA 2518608 p.Met165Thr missense_variant 0.89
eis 2714211 c.1122G>A synonymous_variant 1.0
ahpC 2726250 p.Gly20Arg missense_variant 0.95
thyX 3067787 c.159G>A synonymous_variant 0.17
thyX 3067793 c.153T>C synonymous_variant 0.18
thyX 3067799 c.147G>A synonymous_variant 0.2
thyX 3067802 c.144C>G synonymous_variant 0.2
thyX 3067814 c.132T>C synonymous_variant 0.14
thyX 3067826 c.120C>G synonymous_variant 0.14
thyX 3067850 c.96A>C synonymous_variant 0.14
thyA 3073953 c.519T>C synonymous_variant 0.12
fprA 3473843 c.-164C>G upstream_gene_variant 0.12
fprA 3473848 c.-159C>G upstream_gene_variant 0.12
fprA 3473932 c.-75G>A upstream_gene_variant 1.0
Rv3236c 3612518 p.Tyr200Ser missense_variant 1.0
fbiB 3641684 p.Ser50Arg missense_variant 1.0
rpoA 3877704 c.804G>T synonymous_variant 0.2
rpoA 3877743 c.765T>C synonymous_variant 0.23
rpoA 3877764 c.744C>G synonymous_variant 0.21
rpoA 3877770 c.738A>G synonymous_variant 0.22
rpoA 3877776 c.732T>C synonymous_variant 0.22
rpoA 3877782 c.726T>C synonymous_variant 0.24
rpoA 3877818 c.690A>G synonymous_variant 0.25
rpoA 3877839 c.669G>C synonymous_variant 0.25
rpoA 3877857 c.651G>A synonymous_variant 0.15
rpoA 3877866 c.642G>C synonymous_variant 0.14
rpoA 3877872 c.636C>T synonymous_variant 0.18
rpoA 3877875 c.633T>G synonymous_variant 0.18
rpoA 3877899 p.Ser203Thr missense_variant 0.18
rpoA 3877905 c.603A>G synonymous_variant 0.17
rpoA 3877908 p.Asn200Ser missense_variant 0.17
rpoA 3877962 c.546G>T synonymous_variant 0.17
rpoA 3878141 p.Met123Leu missense_variant 0.2
rpoA 3878142 p.Gly122Glu missense_variant 0.2
rpoA 3878184 c.324C>T synonymous_variant 0.25
rpoA 3878187 c.321C>G synonymous_variant 0.25
rpoA 3878193 c.315T>C synonymous_variant 0.23
rpoA 3878199 c.309T>C synonymous_variant 0.23
rpoA 3878202 c.306G>C synonymous_variant 0.23
rpoA 3878217 c.291A>G synonymous_variant 0.21
rpoA 3878220 c.288C>T synonymous_variant 0.21
rpoA 3878271 c.237T>C synonymous_variant 0.14
rpoA 3878284 p.Glu75Ala missense_variant 0.14
rpoA 3878292 c.216T>C synonymous_variant 0.2
rpoA 3878298 c.210A>G synonymous_variant 0.2
rpoA 3878304 c.204G>C synonymous_variant 0.2
rpoA 3878313 c.195G>C synonymous_variant 0.23
rpoA 3878322 c.186A>G synonymous_variant 0.19
rpoA 3878331 c.177A>G synonymous_variant 0.2
rpoA 3878334 c.174T>C synonymous_variant 0.14
rpoA 3878337 c.171T>C synonymous_variant 0.14
rpoA 3878364 c.144A>G synonymous_variant 0.19
rpoA 3878367 c.141C>G synonymous_variant 0.18
rpoA 3878370 c.138T>C synonymous_variant 0.18
rpoA 3878376 c.132G>C synonymous_variant 0.18
rpoA 3878385 c.123C>G synonymous_variant 0.18
clpC1 4038403 c.2302T>C synonymous_variant 0.14
clpC1 4038434 c.2271G>C synonymous_variant 0.17
clpC1 4038444 p.Ala754Lys missense_variant 0.19
clpC1 4038446 c.2259T>C synonymous_variant 0.18
clpC1 4038452 c.2253G>C synonymous_variant 0.17
clpC1 4038461 p.Ala748Asp missense_variant 0.19
clpC1 4038498 p.Ser736Thr missense_variant 0.13
clpC1 4038914 c.1791G>C synonymous_variant 0.14
clpC1 4038923 c.1782A>G synonymous_variant 0.13
clpC1 4038932 c.1773G>C synonymous_variant 0.17
clpC1 4038989 c.1716T>C synonymous_variant 0.12
clpC1 4039022 c.1683A>G synonymous_variant 0.15
clpC1 4039073 c.1632C>G synonymous_variant 0.19
clpC1 4039097 c.1608G>C synonymous_variant 0.13
clpC1 4039103 c.1602T>C synonymous_variant 0.15
clpC1 4039106 c.1599G>C synonymous_variant 0.14
clpC1 4039121 c.1584T>C synonymous_variant 0.14
clpC1 4039946 c.759A>T synonymous_variant 0.17
clpC1 4039952 c.753T>C synonymous_variant 0.14
clpC1 4039958 c.747G>C synonymous_variant 0.14
clpC1 4039996 p.Glu237Gln missense_variant 0.18
clpC1 4040021 c.684A>C synonymous_variant 0.19
clpC1 4040024 c.681A>G synonymous_variant 0.19
clpC1 4040033 c.672G>C synonymous_variant 0.19
clpC1 4040036 c.669C>G synonymous_variant 0.19
embC 4240183 c.321A>G synonymous_variant 0.13
embC 4240204 c.342T>C synonymous_variant 0.15
embC 4240210 c.348C>G synonymous_variant 0.15
embC 4240216 c.354T>C synonymous_variant 0.15
embC 4240231 c.369G>C synonymous_variant 0.15
embC 4240232 p.Gln124Val missense_variant 0.15
embC 4240258 c.396T>G synonymous_variant 0.15
embC 4240263 p.Val134Ala missense_variant 0.91
embC 4240920 p.Leu353Pro missense_variant 1.0
embC 4241504 p.Val548Met missense_variant 0.95
embA 4244228 c.996A>G synonymous_variant 0.13
embA 4244233 p.Ala334Gly missense_variant 0.12
embA 4244267 c.1035G>C synonymous_variant 0.18
embA 4244276 c.1044A>C synonymous_variant 0.17
embA 4244284 p.Pro351Arg missense_variant 0.18
embA 4244298 p.Ser356Ala missense_variant 0.21
embA 4244309 c.1077C>G synonymous_variant 0.21
embA 4244312 c.1080T>G synonymous_variant 0.21
embA 4244315 c.1083G>C synonymous_variant 0.2
embA 4244324 c.1092T>G synonymous_variant 0.22
embA 4244327 c.1095T>C synonymous_variant 0.22
embA 4244337 p.Leu369Val missense_variant 0.21
embA 4244340 p.Ser370Ala missense_variant 0.22
embA 4244366 c.1134C>G synonymous_variant 0.16
embA 4244372 c.1140T>G synonymous_variant 0.16
embB 4245587 c.-927G>C upstream_gene_variant 0.13
embB 4248000 p.Asp496Val missense_variant 0.95
aftB 4267580 c.1257G>C synonymous_variant 0.12
aftB 4268715 p.Leu41Pro missense_variant 1.0
ethR 4327704 p.Lys52Asn missense_variant 1.0