TB-Profiler result

Run: SRR5818612
Summary

Run ID: SRR5818612

Sample name:

Date: 04-04-2023 11:39:15

Number of reads: 2727713

Percentage reads mapped: 86.35

Strain: lineage4.2.2.2

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.2 Euro-American H;T;LAM None 1.0
lineage4.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
lineage4.2.2.2 Euro-American (Ural) T;LAM7-TUR None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.22 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8688 p.Ala463Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576077 c.730C>T synonymous_variant 0.99
rpoB 761489 c.1683G>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.15
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.17
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.17
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.18
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.24
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.24
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.19
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.28
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.28
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.28
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.16
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.36
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.33
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.32
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.23
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.12
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.23
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.21
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.23
rrs 1472687 n.843dupT non_coding_transcript_exon_variant 0.13
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.26
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.24
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.26
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.25
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.17
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.17
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.13
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.15
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.15
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.15
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.17
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.14
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.11
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.12
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.13
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.12
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.14
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.14
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.13
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.17
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.16
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.17
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.18
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.16
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.11
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.14
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.21
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.1
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.18
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.11
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.17
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.11
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.14
rrl 1475686 n.2029C>G non_coding_transcript_exon_variant 0.16
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.15
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.17
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.15
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.12
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.21
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.16
rrl 1475764 n.2107A>G non_coding_transcript_exon_variant 0.12
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.13
rrl 1475767 n.2110G>T non_coding_transcript_exon_variant 0.14
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.26
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.15
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.14
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.2
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.21
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.13
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.12
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.17
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.18
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.18
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.18
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.15
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.17
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.23
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.26
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.24
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.3
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.26
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.23
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.24
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.23
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.24
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.2
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 0.12
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.21
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.22
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.22
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.25
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.33
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.36
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.34
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.37
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.37
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.36
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.36
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.35
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.34
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.42
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.37
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.13
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.32
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3066280 c.-89C>T upstream_gene_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0