TB-Profiler result

Run: SRR7645856
Summary

Run ID: SRR7645856

Sample name:

Date: 04-04-2023 19:55:13

Number of reads: 3774774

Percentage reads mapped: 67.21

Strain: lineage4.4.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.4 Euro-American S;T None 1.0
lineage4.4.1 Euro-American (S-type) S;T None 1.0
lineage4.4.1.1 Euro-American S;Orphans None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1302887 c.-44T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.11
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.25
rrs 1472108 n.263C>A non_coding_transcript_exon_variant 0.25
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.36
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 0.34
rrs 1472129 n.284G>T non_coding_transcript_exon_variant 0.36
rrs 1472135 n.290C>G non_coding_transcript_exon_variant 0.39
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.37
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.39
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.4
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.4
rrs 1472153 n.308G>C non_coding_transcript_exon_variant 0.41
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.46
rrs 1472707 n.862A>G non_coding_transcript_exon_variant 0.17
rrs 1472708 n.863T>A non_coding_transcript_exon_variant 0.16
rrs 1472715 n.870C>G non_coding_transcript_exon_variant 0.22
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 0.22
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.51
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.52
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.51
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.54
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.52
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.22
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.22
rrs 1473139 n.1294T>C non_coding_transcript_exon_variant 0.13
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.16
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.19
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.36
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.37
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.36
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.36
rrs 1473198 n.1354delC non_coding_transcript_exon_variant 0.37
rrs 1473202 n.1357C>T non_coding_transcript_exon_variant 0.36
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.38
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.37
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.4
rrl 1476356 n.2699C>A non_coding_transcript_exon_variant 0.51
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.52
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.51
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.51
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.53
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.55
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.55
rrl 1476383 n.2726T>G non_coding_transcript_exon_variant 0.55
rrl 1476384 n.2727G>T non_coding_transcript_exon_variant 0.55
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.67
rrl 1476411 n.2754G>T non_coding_transcript_exon_variant 0.68
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.69
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.65
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.66
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.62
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.62
rrl 1476463 n.2806C>A non_coding_transcript_exon_variant 0.57
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.57
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.33
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.14
rrl 1476588 n.2931A>G non_coding_transcript_exon_variant 0.13
rrl 1476595 n.2938C>A non_coding_transcript_exon_variant 0.13
rrl 1476602 n.2945G>T non_coding_transcript_exon_variant 0.13
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.12
rrl 1476611 n.2954T>C non_coding_transcript_exon_variant 0.13
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 0.13
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.13
rrl 1476621 n.2964C>T non_coding_transcript_exon_variant 0.13
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.12
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.12
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102990 p.Val18Ala missense_variant 1.0
PPE35 2169840 p.Gly258Asp missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448608 c.105G>A synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612665 p.Val151Ala missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407965 p.Ala80Thr missense_variant 1.0