TB-Profiler result

Run: ERR4820107
Summary

Run ID: ERR4820107

Sample name:

Date: 01-04-2023 16:29:19

Number of reads: 527249

Percentage reads mapped: 38.91

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1 Indo-Oceanic EAI RD239 0.99
lineage1.2.1.2 Indo-Oceanic NA RD239 0.97
lineage1.2.1.2.1 Indo-Oceanic NA RD239 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.31 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.83 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.19 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8452 p.Ala384Val missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9260 c.1959G>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575368 c.21T>C synonymous_variant 1.0
rpoB 761102 c.1296A>G synonymous_variant 0.36
rpoB 761132 c.1326G>T synonymous_variant 0.23
rpoB 761133 c.1327T>C synonymous_variant 0.29
rpoB 761150 c.1344A>C synonymous_variant 0.21
rpoB 761154 c.1348_1350delTCGinsAGC synonymous_variant 0.21
rpoB 761159 c.1353G>C synonymous_variant 0.14
rpoB 761165 c.1359G>C synonymous_variant 0.2
rpoB 761180 c.1374A>C synonymous_variant 0.15
rpoB 761189 c.1383T>C synonymous_variant 0.18
rpoB 762017 p.Glu737Asp missense_variant 0.13
rpoB 762024 p.Val740Met missense_variant 0.13
rpoB 762053 c.2247T>C synonymous_variant 0.14
rpoB 762057 p.Ile751Val missense_variant 0.13
rpoB 762110 c.2304G>C synonymous_variant 0.16
rpoB 762114 p.Ile770Val missense_variant 0.17
rpoB 762143 c.2337T>C synonymous_variant 0.17
rpoB 762149 c.2343G>C synonymous_variant 0.19
rpoB 762156 p.Val784Ile missense_variant 0.15
rpoB 762167 c.2361T>C synonymous_variant 0.23
rpoB 762194 c.2388G>C synonymous_variant 0.12
rpoC 762887 c.-483G>C upstream_gene_variant 0.13
rpoC 762899 c.-471G>C upstream_gene_variant 0.12
rpoC 762920 c.-450C>T upstream_gene_variant 0.14
rpoC 762929 c.-441G>C upstream_gene_variant 0.12
rpoC 762938 c.-432G>C upstream_gene_variant 0.18
rpoC 762980 c.-390T>C upstream_gene_variant 0.2
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763053 c.-317T>C upstream_gene_variant 0.29
rpoC 763067 c.-303C>G upstream_gene_variant 0.22
rpoC 763070 c.-300T>C upstream_gene_variant 0.22
rpoB 763077 p.Val1091Thr missense_variant 0.25
rpoC 763103 c.-267G>C upstream_gene_variant 0.18
rpoC 763109 c.-261C>T upstream_gene_variant 0.2
rpoC 763115 c.-255T>C upstream_gene_variant 0.2
rpoB 763119 p.Asn1105Asp missense_variant 0.2
rpoC 763127 c.-243G>C upstream_gene_variant 0.22
rpoC 763133 c.-237G>C upstream_gene_variant 0.22
rpoC 763504 c.135C>A synonymous_variant 0.15
rpoC 763507 c.138G>C synonymous_variant 0.15
rpoC 763528 c.159G>C synonymous_variant 0.27
rpoC 763531 c.162G>C synonymous_variant 1.0
rpoC 763534 c.165T>C synonymous_variant 0.21
rpoC 763537 c.168C>G synonymous_variant 0.23
rpoC 763546 c.177A>G synonymous_variant 0.27
rpoC 763550 p.Tyr61Ala missense_variant 0.33
rpoC 763570 c.201G>C synonymous_variant 0.23
rpoC 763578 p.Phe70Tyr missense_variant 0.21
rpoC 763585 c.216C>G synonymous_variant 0.14
rpoC 763598 p.Arg77Ser missense_variant 0.15
rpoC 763699 c.330G>T synonymous_variant 0.19
rpoC 763708 c.339G>C synonymous_variant 0.18
rpoC 763714 c.345G>C synonymous_variant 0.19
rpoC 763717 c.348T>C synonymous_variant 0.19
rpoC 763718 p.Leu117Val missense_variant 0.12
rpoC 763723 c.354G>C synonymous_variant 0.18
rpoC 763724 p.Asp119Asn missense_variant 0.18
rpoC 763729 c.360G>C synonymous_variant 0.19
rpoC 763732 c.363C>G synonymous_variant 0.19
rpoC 763735 c.366G>C synonymous_variant 0.19
rpoC 763751 p.Ile128Val missense_variant 0.17
rpoC 763772 p.Val135Met missense_variant 0.17
rpoC 763884 p.Ala172Val missense_variant 1.0
rpoC 763886 c.517C>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpS5 779505 c.-600A>C upstream_gene_variant 0.14
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406312 c.1029T>C synonymous_variant 1.0
embR 1416278 p.Ile357Thr missense_variant 0.25
embR 1417019 p.Cys110Tyr missense_variant 1.0
atpE 1460907 c.-138T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.5
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.57
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.59
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.79
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.76
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.94
rrs 1472150 n.305T>G non_coding_transcript_exon_variant 0.9
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.3
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.67
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.48
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.44
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.3
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.87
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.32
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.47
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 1.0
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 1.0
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 1.0
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 1.0
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 1.0
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 1.0
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.75
rrs 1472506 n.661A>G non_coding_transcript_exon_variant 0.13
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.65
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.24
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.63
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.61
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.77
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.81
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.84
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.83
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.8
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.84
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.72
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.67
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.45
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.96
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.99
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.17
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.83
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.84
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.56
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.25
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.75
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.71
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.71
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.83
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.82
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.15
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.79
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.82
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.81
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.81
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.18
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.79
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.81
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.96
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.16
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.62
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.94
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.85
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.12
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.32
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.12
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.75
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.52
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.36
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.86
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.86
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.36
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.3
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.93
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.46
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.46
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.91
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.81
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.9
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.91
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.29
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.95
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.14
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.7
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.74
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.42
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.22
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.94
rrs 1473109 n.1264T>C non_coding_transcript_exon_variant 0.22
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.94
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.94
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.2
rrs 1473116 n.1271A>G non_coding_transcript_exon_variant 0.15
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.86
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.72
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.46
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.74
rrs 1473147 n.1302G>T non_coding_transcript_exon_variant 0.17
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.29
rrs 1473150 n.1305T>G non_coding_transcript_exon_variant 0.17
rrs 1473161 n.1316A>C non_coding_transcript_exon_variant 0.21
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.3
rrs 1473164 n.1319C>A non_coding_transcript_exon_variant 0.2
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.73
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.33
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.46
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.29
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.34
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.31
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.33
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.4
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.25
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.26
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.84
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.26
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.94
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.31
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.13
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.8
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.57
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.5
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.67
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.75
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.33
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.8
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 1.0
rrl 1474163 n.506C>T non_coding_transcript_exon_variant 0.67
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.67
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 1.0
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.83
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0
rrl 1474393 n.736A>G non_coding_transcript_exon_variant 1.0
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 1.0
rrl 1474406 n.749T>C non_coding_transcript_exon_variant 0.67
rrl 1474437 n.781_782delAA non_coding_transcript_exon_variant 1.0
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 0.75
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.89
rrl 1474492 n.835A>G non_coding_transcript_exon_variant 0.22
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.8
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.9
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.9
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.9
rrl 1474520 n.863A>T non_coding_transcript_exon_variant 0.2
rrl 1474525 n.868A>G non_coding_transcript_exon_variant 0.18
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.73
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.2
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.17
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.17
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.25
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.8
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.5
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.67
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.67
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 0.4
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.6
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.4
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.5
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.5
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.6
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.29
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.22
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.89
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.83
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.75
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.33
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.33
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.4
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 1.0
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 1.0
rrl 1475172 n.1515A>G non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 1.0
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.25
rrl 1475754 n.2097G>A non_coding_transcript_exon_variant 0.38
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.38
rrl 1475772 n.2115A>C non_coding_transcript_exon_variant 0.38
rrl 1475774 n.2117C>T non_coding_transcript_exon_variant 0.38
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 1.0
rrl 1475879 n.2222T>C non_coding_transcript_exon_variant 0.14
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.57
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.91
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.54
rrl 1475892 n.2235A>C non_coding_transcript_exon_variant 0.4
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.25
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.5
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.5
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.62
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.25
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.25
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.75
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.75
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 1.0
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.67
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 1.0
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 1.0
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.29
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.43
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.5
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 1.0
rrl 1476187 n.2530T>C non_coding_transcript_exon_variant 0.57
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.25
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.75
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.5
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.38
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.75
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.57
rrl 1476357 n.2700T>C non_coding_transcript_exon_variant 0.5
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.86
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.16
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.79
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.18
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.67
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.45
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.63
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.78
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.73
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.5
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.5
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.5
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.67
rrl 1476535 n.2878G>A non_coding_transcript_exon_variant 0.25
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.29
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.43
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.43
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.43
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.4
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.7
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.43
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.86
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.86
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.43
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 1.0
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 1.0
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.8
rrl 1476645 n.2988A>G non_coding_transcript_exon_variant 0.5
rrl 1476664 n.3007T>A non_coding_transcript_exon_variant 0.67
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.67
inhA 1674162 c.-40C>T upstream_gene_variant 1.0
rpsA 1833727 c.186G>C synonymous_variant 0.15
rpsA 1833732 p.Pro64Leu missense_variant 0.14
rpsA 1833736 c.195C>T synonymous_variant 0.15
rpsA 1833742 c.201A>G synonymous_variant 0.14
rpsA 1833770 p.Asn77Asp missense_variant 0.17
rpsA 1833776 p.Val79Ile missense_variant 0.15
rpsA 1833781 c.240T>C synonymous_variant 0.15
rpsA 1833790 c.249T>C synonymous_variant 0.15
rpsA 1833797 p.Val86Ile missense_variant 0.17
rpsA 1833994 c.453G>C synonymous_variant 0.11
rpsA 1834000 c.459G>C synonymous_variant 0.11
rpsA 1834012 c.471G>C synonymous_variant 0.2
rpsA 1834034 p.Ile165Val missense_variant 0.2
rpsA 1834040 p.Lys167Arg missense_variant 0.13
rpsA 1834046 p.Ile169Leu missense_variant 0.21
rpsA 1834054 c.513C>G synonymous_variant 0.13
rpsA 1834069 c.528G>C synonymous_variant 0.15
rpsA 1834195 c.654G>C synonymous_variant 0.12
rpsA 1834210 c.669C>T synonymous_variant 0.14
rpsA 1834219 c.678C>G synonymous_variant 0.14
rpsA 1834222 c.681T>C synonymous_variant 0.14
rpsA 1834225 c.684C>G synonymous_variant 0.23
rpsA 1834228 c.687C>T synonymous_variant 0.15
rpsA 1834246 c.705G>T synonymous_variant 0.14
rpsA 1834249 c.708T>C synonymous_variant 0.15
rpsA 1834261 c.720A>G synonymous_variant 0.15
rpsA 1834264 c.723G>C synonymous_variant 0.14
rpsA 1834411 c.870T>C synonymous_variant 0.18
rpsA 1834417 c.876G>C synonymous_variant 0.22
rpsA 1834423 c.882G>C synonymous_variant 0.2
rpsA 1834427 p.Ile296Val missense_variant 0.2
rpsA 1834435 c.894G>C synonymous_variant 0.27
rpsA 1834451 c.910_912delTTGinsCTC synonymous_variant 0.25
rpsA 1834456 c.915T>C synonymous_variant 0.25
rpsA 1834459 c.918G>C synonymous_variant 0.25
rpsA 1834465 c.924T>C synonymous_variant 0.25
rpsA 1834468 c.927A>G synonymous_variant 0.25
rpsA 1834489 c.948T>C synonymous_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918704 c.765A>G synonymous_variant 0.2
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2290226 c.-985T>C upstream_gene_variant 0.18
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2519048 p.Gly312Ser missense_variant 1.0
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
folC 2746167 p.Ala478Ser missense_variant 0.15
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087470 c.651T>C synonymous_variant 0.2
fbiD 3339417 c.300A>G synonymous_variant 1.0
Rv3083 3448714 p.Asp71His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
whiB7 3568488 c.191delG frameshift_variant 1.0
fbiB 3640557 c.-978T>C upstream_gene_variant 1.0
fbiB 3642441 p.Pro303Ser missense_variant 0.2
rpoA 3878108 p.Leu134Met missense_variant 0.29
clpC1 4038835 p.Phe624Leu missense_variant 0.13
clpC1 4040517 p.Val63Ala missense_variant 1.0
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241042 p.Asn394Asp missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243580 c.348G>A synonymous_variant 1.0
embA 4244420 c.1188G>C synonymous_variant 1.0
embA 4245969 p.Pro913Ser missense_variant 1.0
embB 4247578 c.1065G>A synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ubiA 4269864 c.-32delG upstream_gene_variant 1.0
whiB6 4338361 p.Arg54Gln missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0