TB-Profiler result

Run: ERR736818
Summary

Run ID: ERR736818

Sample name:

Date: 02-04-2023 04:19:05

Number of reads: 4101233

Percentage reads mapped: 72.01

Strain: lineage4.3.3

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.3 Euro-American (LAM) LAM;T RD115 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.11
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 0.11
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.14
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.15
rrs 1472697 n.852T>G non_coding_transcript_exon_variant 0.2
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.31
rrs 1472708 n.863T>A non_coding_transcript_exon_variant 0.43
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.64
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.64
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.62
rrs 1472786 n.941C>T non_coding_transcript_exon_variant 0.61
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.57
rrs 1472803 n.958T>C non_coding_transcript_exon_variant 0.47
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.15
rrs 1473147 n.1302G>C non_coding_transcript_exon_variant 0.21
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.24
rrs 1473150 n.1305T>G non_coding_transcript_exon_variant 0.25
rrs 1473161 n.1316A>C non_coding_transcript_exon_variant 0.28
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.27
rrs 1473164 n.1319C>G non_coding_transcript_exon_variant 0.21
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.38
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.26
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.26
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.26
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.26
rrs 1473262 n.1417T>A non_coding_transcript_exon_variant 0.26
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.12
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.16
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.19
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.19
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.2
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.2
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.17
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.16
rrl 1475869 n.2212C>T non_coding_transcript_exon_variant 0.17
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 1.0
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.31
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.34
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.34
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.36
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.38
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.38
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.38
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.37
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.4
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.5
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.51
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.51
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.63
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.64
rrl 1476353 n.2696G>A non_coding_transcript_exon_variant 0.63
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.61
rrl 1476359 n.2702C>T non_coding_transcript_exon_variant 0.62
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.68
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.68
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.69
rrl 1476411 n.2754G>A non_coding_transcript_exon_variant 0.69
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.68
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.66
rrl 1476463 n.2806C>T non_coding_transcript_exon_variant 0.57
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.56
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.54
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.52
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.35
rrl 1476513 n.2856G>A non_coding_transcript_exon_variant 0.17
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.16
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.14
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.12
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.11
rrl 1476565 n.2908G>A non_coding_transcript_exon_variant 0.18
rrl 1476566 n.2909A>G non_coding_transcript_exon_variant 0.18
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.18
rrl 1476577 n.2920T>A non_coding_transcript_exon_variant 0.23
rrl 1476578 n.2921C>A non_coding_transcript_exon_variant 0.23
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.22
rrl 1476592 n.2935G>A non_coding_transcript_exon_variant 0.23
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.23
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.23
rrl 1476605 n.2948C>T non_coding_transcript_exon_variant 0.24
rrl 1476608 n.2951C>A non_coding_transcript_exon_variant 0.22
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 0.23
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.25
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.24
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.24
rrl 1476637 n.2980C>A non_coding_transcript_exon_variant 0.25
inhA 1674748 p.Gly183Ser missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 1.0
Rv2752c 3065824 p.Pro123Leu missense_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245083 c.1851A>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0