TB-Profiler result

Run: SRR069981
Summary

Run ID: SRR069981

Sample name:

Date: 02-04-2023 14:18:09

Number of reads: 1402019

Percentage reads mapped: 76.21

Strain: lineage2.2.2

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.98
lineage2.2.2 East-Asian (Beijing) Beijing-RD105/RD207 RD105;RD207 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrA 7570 p.Ala90Val missense_variant 0.89 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.17 streptomycin
katG 2155108 c.1002_1003dupGA frameshift_variant 0.95 isoniazid
kasA 2518310 p.Asp66Asn missense_variant 1.0 isoniazid
embB 4247448 p.His312Arg missense_variant 0.2 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6793 c.-509T>C upstream_gene_variant 0.13
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7391 c.90C>T synonymous_variant 0.22
gyrA 7394 c.93T>C synonymous_variant 0.2
gyrA 7427 c.126G>C synonymous_variant 0.18
gyrA 7517 c.216G>A synonymous_variant 0.13
gyrA 7523 c.222C>G synonymous_variant 0.14
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7760 c.459C>T synonymous_variant 0.18
gyrA 7763 c.462T>C synonymous_variant 0.24
gyrA 7799 c.498A>G synonymous_variant 0.19
gyrA 8198 c.897T>C synonymous_variant 0.16
gyrA 8294 c.993T>C synonymous_variant 0.14
gyrA 8324 c.1023T>C synonymous_variant 0.18
gyrA 8339 c.1038A>G synonymous_variant 0.18
gyrA 8351 c.1050C>T synonymous_variant 0.15
gyrA 8391 p.Tyr364His missense_variant 0.16
gyrA 8399 c.1098T>C synonymous_variant 0.2
gyrA 8420 c.1119T>C synonymous_variant 0.19
gyrA 8423 c.1122G>C synonymous_variant 0.15
gyrA 8636 c.1335A>C synonymous_variant 0.15
gyrA 8642 c.1341A>G synonymous_variant 0.16
gyrA 8829 c.1528T>C synonymous_variant 0.2
gyrA 8852 c.1551T>C synonymous_variant 0.14
gyrA 9164 c.1863G>C synonymous_variant 0.19
gyrA 9182 c.1881T>C synonymous_variant 0.2
gyrA 9191 c.1890G>C synonymous_variant 0.27
gyrA 9200 c.1899A>G synonymous_variant 0.28
gyrA 9204 p.Ser635Thr missense_variant 0.29
gyrA 9227 c.1926C>G synonymous_variant 0.23
gyrA 9230 c.1929T>C synonymous_variant 0.23
gyrA 9233 c.1932C>T synonymous_variant 0.21
gyrA 9242 c.1941A>C synonymous_variant 0.23
gyrA 9252 p.Val651Ile missense_variant 0.19
gyrA 9275 c.1974G>A synonymous_variant 0.13
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9383 c.2082T>C synonymous_variant 0.13
gyrA 9386 c.2085T>C synonymous_variant 0.13
gyrA 9665 c.2364A>G synonymous_variant 0.17
gyrA 9666 p.Arg789Gly missense_variant 0.19
gyrA 9674 c.2373T>C synonymous_variant 0.32
gyrA 9677 c.2376C>T synonymous_variant 0.29
gyrA 9701 c.2400T>C synonymous_variant 0.33
gyrA 9704 c.2403T>C synonymous_variant 0.32
gyrA 9708 c.2407T>C synonymous_variant 0.35
gyrA 9722 c.2421C>T synonymous_variant 0.23
gyrA 9734 c.2433A>G synonymous_variant 0.15
fgd1 490827 c.45C>T synonymous_variant 0.2
fgd1 490833 c.51G>C synonymous_variant 0.23
fgd1 490842 c.60C>G synonymous_variant 0.24
fgd1 490851 c.69A>C synonymous_variant 0.22
fgd1 491144 p.Ala121Asp missense_variant 0.14
fgd1 491583 c.801G>A synonymous_variant 0.26
fgd1 491595 c.813C>G synonymous_variant 0.22
fgd1 491601 c.819T>C synonymous_variant 0.18
fgd1 491610 c.828A>C synonymous_variant 0.19
fgd1 491616 c.834A>G synonymous_variant 0.14
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575821 c.474G>C synonymous_variant 0.38
mshA 575824 c.477T>G synonymous_variant 0.43
mshA 575864 c.517T>C synonymous_variant 0.22
mshA 575878 c.531A>G synonymous_variant 0.17
ccsA 620362 p.Ala158Thr missense_variant 0.17
ccsA 620367 c.477T>C synonymous_variant 0.18
ccsA 620373 c.483C>G synonymous_variant 0.13
ccsA 620385 c.495G>C synonymous_variant 0.18
ccsA 620388 c.498A>G synonymous_variant 0.21
ccsA 620412 c.522T>C synonymous_variant 0.21
ccsA 620415 c.525T>C synonymous_variant 0.17
ccsA 620619 c.729G>T synonymous_variant 0.15
ccsA 620787 c.897C>G synonymous_variant 0.2
ccsA 620809 c.919C>T synonymous_variant 0.22
rpoB 760181 c.375T>C synonymous_variant 0.15
rpoB 760184 c.378A>G synonymous_variant 0.15
rpoB 760223 c.417T>C synonymous_variant 0.19
rpoB 760235 c.429T>C synonymous_variant 0.2
rpoB 760253 c.447T>C synonymous_variant 0.19
rpoB 760418 c.612G>C synonymous_variant 0.22
rpoB 760424 c.618C>G synonymous_variant 0.22
rpoB 760430 c.624T>C synonymous_variant 0.23
rpoB 760475 c.669A>G synonymous_variant 0.21
rpoB 760522 p.Ser239Asn missense_variant 0.18
rpoB 760547 c.741G>C synonymous_variant 0.14
rpoB 760591 p.Val262Ala missense_variant 0.29
rpoB 760611 c.805T>C synonymous_variant 0.36
rpoB 760634 c.828T>C synonymous_variant 0.23
rpoB 760919 c.1113C>G synonymous_variant 0.16
rpoB 760934 c.1128C>T synonymous_variant 0.21
rpoB 760946 c.1140A>G synonymous_variant 0.23
rpoB 760970 c.1164G>C synonymous_variant 0.18
rpoB 760982 c.1176G>C synonymous_variant 0.15
rpoB 760985 c.1179G>C synonymous_variant 0.18
rpoB 760991 c.1185G>C synonymous_variant 0.18
rpoB 761222 c.1416G>C synonymous_variant 0.22
rpoB 761249 c.1443A>G synonymous_variant 0.17
rpoB 761255 c.1449T>G synonymous_variant 0.18
rpoB 761261 c.1455G>T synonymous_variant 0.14
rpoB 761297 c.1491C>T synonymous_variant 0.12
rpoB 761360 c.1554T>C synonymous_variant 0.17
rpoB 761362 p.Ser519Thr missense_variant 0.17
rpoB 761373 p.Val523His missense_variant 0.2
rpoB 761510 c.1704T>C synonymous_variant 0.2
rpoB 761531 c.1725C>G synonymous_variant 0.23
rpoB 761537 c.1731C>G synonymous_variant 0.21
rpoB 761570 c.1764T>C synonymous_variant 0.19
rpoB 761573 c.1767C>G synonymous_variant 0.18
rpoB 761579 c.1773G>C synonymous_variant 0.18
rpoB 761606 c.1800C>G synonymous_variant 0.32
rpoB 761612 c.1806G>C synonymous_variant 0.29
rpoB 761615 c.1809A>C synonymous_variant 0.27
rpoB 761636 c.1830G>T synonymous_variant 0.27
rpoB 761645 c.1839C>G synonymous_variant 0.24
rpoB 761648 c.1842T>C synonymous_variant 0.26
rpoB 761657 c.1851C>G synonymous_variant 0.23
rpoB 761675 c.1869G>C synonymous_variant 0.14
rpoB 762167 c.2361T>C synonymous_variant 0.15
rpoB 762176 c.2370T>C synonymous_variant 0.21
rpoB 762185 c.2379G>C synonymous_variant 0.22
rpoB 762218 c.2412T>G synonymous_variant 0.14
rpoB 762254 c.2448T>C synonymous_variant 0.23
rpoB 762284 c.2478G>C synonymous_variant 0.15
rpoB 762293 c.2487T>C synonymous_variant 0.13
rpoC 762533 c.-837T>C upstream_gene_variant 0.19
rpoC 762536 c.-834T>C upstream_gene_variant 0.19
rpoC 762537 c.-833T>C upstream_gene_variant 0.19
rpoC 762551 c.-819C>T upstream_gene_variant 0.24
rpoC 762581 c.-789T>C upstream_gene_variant 0.14
rpoC 762582 c.-788T>C upstream_gene_variant 0.14
rpoC 762857 c.-513C>G upstream_gene_variant 0.23
rpoC 762860 c.-510G>C upstream_gene_variant 0.2
rpoC 762863 c.-507T>C upstream_gene_variant 0.21
rpoC 762929 c.-441G>C upstream_gene_variant 0.15
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763226 c.-144A>G upstream_gene_variant 0.14
rpoC 763238 c.-132T>C upstream_gene_variant 0.13
rpoC 763402 c.33C>G synonymous_variant 0.19
rpoC 763411 c.42T>G synonymous_variant 0.18
rpoC 763414 c.45T>C synonymous_variant 0.18
rpoC 763441 c.72C>G synonymous_variant 0.13
rpoC 763444 c.75T>C synonymous_variant 0.13
rpoC 763456 c.87A>G synonymous_variant 0.19
rpoC 763468 c.99G>C synonymous_variant 0.17
rpoC 763486 c.117T>C synonymous_variant 0.18
rpoC 763528 c.159G>A synonymous_variant 0.26
rpoC 763546 c.177A>G synonymous_variant 0.2
rpoC 763570 c.201G>C synonymous_variant 0.29
rpoC 763594 c.225C>T synonymous_variant 0.18
rpoC 763633 c.264T>C synonymous_variant 0.22
rpoC 763636 c.267T>C synonymous_variant 0.23
rpoC 763642 c.273G>C synonymous_variant 0.17
rpoC 763658 c.289_291delCTTinsTTG synonymous_variant 0.23
rpoC 763675 c.306C>G synonymous_variant 0.14
rpoC 763732 c.363C>G synonymous_variant 0.13
rpoC 763735 c.366G>C synonymous_variant 0.14
rpoC 763744 c.375G>C synonymous_variant 0.15
rpoC 763765 c.396T>C synonymous_variant 0.19
rpoC 763768 c.399C>G synonymous_variant 0.19
rpoC 763780 c.411C>G synonymous_variant 0.18
rpoC 763783 c.414G>C synonymous_variant 0.18
rpoC 763801 c.432C>G synonymous_variant 0.16
rpoC 764005 c.636G>C synonymous_variant 0.17
rpoC 764011 c.642T>C synonymous_variant 0.17
rpoC 764024 c.655T>C synonymous_variant 0.18
rpoC 764040 p.Ser224Asn missense_variant 0.19
rpoC 764044 c.675T>C synonymous_variant 0.22
rpoC 764059 c.690G>C synonymous_variant 0.21
rpoC 764131 c.762T>C synonymous_variant 0.23
rpoC 764161 c.792G>C synonymous_variant 0.23
rpoC 764188 c.819A>G synonymous_variant 0.24
rpoC 764195 p.Ser276Gln missense_variant 0.18
rpoC 764203 c.834G>T synonymous_variant 0.2
rpoC 764206 c.837T>C synonymous_variant 0.24
rpoC 764257 c.888G>C synonymous_variant 0.21
rpoC 764266 c.897T>C synonymous_variant 0.27
rpoC 764269 c.900G>C synonymous_variant 0.25
rpoC 764282 c.913_915delTCGinsAGC synonymous_variant 0.23
rpoC 764365 c.996C>T synonymous_variant 0.2
rpoC 764405 c.1036A>C synonymous_variant 0.14
rpoC 764695 c.1326T>C synonymous_variant 0.18
rpoC 764716 c.1347G>C synonymous_variant 0.23
rpoC 764752 c.1383G>C synonymous_variant 0.16
rpoC 764764 c.1395T>C synonymous_variant 0.21
rpoC 764791 c.1422C>G synonymous_variant 0.17
rpoC 764809 c.1440C>T synonymous_variant 0.14
rpoC 764812 c.1443C>G synonymous_variant 0.17
rpoC 764815 c.1446A>G synonymous_variant 0.17
rpoC 764824 c.1455T>C synonymous_variant 0.13
rpoC 765383 p.Met672Leu missense_variant 0.16
rpoC 765404 p.Leu679Val missense_variant 0.19
rpoC 765409 c.2040T>C synonymous_variant 0.21
rpoC 765412 c.2043T>C synonymous_variant 0.24
rpoC 765421 c.2052C>G synonymous_variant 0.25
rpoC 765451 c.2082C>G synonymous_variant 0.21
rpoC 765452 p.Ala695Ser missense_variant 0.21
rpoC 765478 c.2109T>C synonymous_variant 0.16
rpoC 765499 c.2130C>G synonymous_variant 0.15
rpoC 765508 c.2139C>G synonymous_variant 0.15
rpoC 765583 c.2214G>T synonymous_variant 0.17
rpoC 765613 p.His748Gln missense_variant 0.3
rpoC 765625 c.2256C>G synonymous_variant 0.23
rpoC 765628 c.2259G>C synonymous_variant 0.26
rpoC 765631 p.Asp754Glu missense_variant 0.27
rpoC 765658 c.2289C>T synonymous_variant 0.2
rpoC 765700 c.2331T>C synonymous_variant 0.25
rpoC 765734 c.2365T>C synonymous_variant 0.24
rpoC 765739 c.2370G>C synonymous_variant 0.23
rpoC 765751 c.2382C>G synonymous_variant 0.16
rpoC 765753 p.Asp795Ala missense_variant 0.16
rpoC 765826 c.2457T>C synonymous_variant 0.15
rpoC 765835 c.2466C>T synonymous_variant 0.19
rpoC 765883 c.2514C>G synonymous_variant 0.18
rpoC 765886 c.2517C>G synonymous_variant 0.17
rpoC 765892 c.2523T>C synonymous_variant 0.25
rpoC 765928 c.2559C>G synonymous_variant 0.27
rpoC 765967 c.2598C>T synonymous_variant 0.23
rpoC 765979 c.2610C>G synonymous_variant 0.25
rpoC 765982 c.2613C>T synonymous_variant 0.24
rpoC 765985 c.2616C>T synonymous_variant 0.24
rpoC 765994 c.2625A>T synonymous_variant 0.23
rpoC 766054 c.2685C>G synonymous_variant 0.14
rpoC 766069 c.2700G>A synonymous_variant 0.14
rpoC 766082 p.Ala905Gln missense_variant 0.14
rpoC 766096 c.2727G>C synonymous_variant 0.14
rpoC 766105 c.2736C>T synonymous_variant 0.19
rpoC 766129 c.2760C>G synonymous_variant 0.14
rpoC 766483 c.3114G>C synonymous_variant 0.14
rpoC 766484 p.Val1039Ile missense_variant 0.14
rpoC 766489 c.3120G>T synonymous_variant 0.17
rpoC 766492 c.3123T>C synonymous_variant 0.17
rpoC 766522 c.3153C>G synonymous_variant 0.19
rpoC 766528 c.3159T>C synonymous_variant 0.19
rpoC 766531 c.3162G>T synonymous_variant 0.19
rpoC 766543 c.3174C>T synonymous_variant 0.19
rpoC 766549 c.3180G>C synonymous_variant 0.29
rpoC 766573 c.3204T>C synonymous_variant 0.24
rpoC 766583 p.Gly1072Ser missense_variant 0.17
rpoC 766588 c.3219G>A synonymous_variant 0.15
rpoC 766591 c.3222A>G synonymous_variant 0.16
rpoC 766738 c.3369G>T synonymous_variant 0.15
rpoC 766750 c.3381C>G synonymous_variant 0.17
rpoC 766765 c.3396A>C synonymous_variant 0.14
rpoC 766804 c.3435A>G synonymous_variant 0.28
rpoC 767035 c.3666G>T synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776120 c.2361C>T synonymous_variant 0.14
mmpL5 776129 c.2352C>G synonymous_variant 0.12
mmpL5 776132 c.2349A>G synonymous_variant 0.17
mmpL5 776693 c.1788C>G synonymous_variant 0.14
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781571 c.12C>T synonymous_variant 0.17
rpsL 781608 p.Ser17Gly missense_variant 0.26
rpsL 781631 c.72G>C synonymous_variant 0.34
rpsL 781649 c.90T>C synonymous_variant 0.26
rpsL 781655 c.96T>C synonymous_variant 0.26
rpsL 781682 c.123T>C synonymous_variant 0.21
rpsL 781793 c.234G>C synonymous_variant 0.29
rpsL 781832 c.273T>C synonymous_variant 0.29
rpsL 781841 c.282C>G synonymous_variant 0.26
rpsL 781859 c.300T>C synonymous_variant 0.2
rpsL 781868 c.309T>C synonymous_variant 0.17
rpsL 781871 c.312G>C synonymous_variant 0.21
rpsL 781892 c.333A>G synonymous_variant 0.18
rpsL 781898 c.339A>T synonymous_variant 0.2
rpsL 781916 c.357T>C synonymous_variant 0.21
rpsL 781929 p.Gly124Ser missense_variant 0.32
rplC 800612 c.-197A>G upstream_gene_variant 0.19
rplC 800618 c.-191T>C upstream_gene_variant 0.16
rplC 800648 c.-161A>C upstream_gene_variant 0.17
rplC 800693 c.-116A>G upstream_gene_variant 0.14
rplC 800738 c.-71T>C upstream_gene_variant 0.14
rplC 800771 c.-38C>T upstream_gene_variant 0.14
rplC 800814 c.6A>G synonymous_variant 0.14
rplC 800817 c.9A>T synonymous_variant 0.14
rplC 800844 c.36T>C synonymous_variant 0.16
rplC 800865 c.57A>G synonymous_variant 0.19
rplC 800867 p.Ser20Asn missense_variant 0.19
rplC 800874 c.66A>G synonymous_variant 0.18
rplC 800877 c.69A>C synonymous_variant 0.17
rplC 800880 c.72A>G synonymous_variant 0.18
rplC 800889 c.81C>G synonymous_variant 0.14
rplC 800907 c.99C>G synonymous_variant 0.17
rplC 800916 c.108A>G synonymous_variant 0.14
rplC 800940 c.132C>G synonymous_variant 0.13
rplC 800946 c.138T>C synonymous_variant 0.15
rplC 800949 c.141T>C synonymous_variant 0.13
rplC 800955 c.147C>G synonymous_variant 0.14
fbiC 1303911 c.981G>C synonymous_variant 0.24
fbiC 1303914 c.984C>G synonymous_variant 0.13
fbiC 1303920 c.990C>G synonymous_variant 0.14
fbiC 1303923 c.993C>T synonymous_variant 0.14
fbiC 1304545 p.Val539Thr missense_variant 0.14
fbiC 1304559 p.Glu543Asp missense_variant 0.16
fbiC 1304568 c.1638T>C synonymous_variant 0.17
fbiC 1304574 c.1644C>G synonymous_variant 0.23
fbiC 1304580 c.1650T>C synonymous_variant 0.25
fbiC 1304613 c.1683T>C synonymous_variant 0.17
fbiC 1304628 c.1698G>C synonymous_variant 0.15
fbiC 1304916 c.1986T>C synonymous_variant 0.29
fbiC 1304925 c.1995G>C synonymous_variant 0.29
fbiC 1304928 c.1998T>C synonymous_variant 0.25
fbiC 1304934 c.2004C>G synonymous_variant 0.26
fbiC 1304937 c.2007G>C synonymous_variant 0.25
fbiC 1304940 c.2010A>G synonymous_variant 0.29
fbiC 1304946 c.2016G>C synonymous_variant 0.36
fbiC 1304958 c.2028T>G synonymous_variant 0.35
fbiC 1304991 c.2061G>C synonymous_variant 0.26
fbiC 1304994 c.2064A>G synonymous_variant 0.28
fbiC 1304995 c.2065T>C synonymous_variant 0.28
fbiC 1305006 c.2076A>G synonymous_variant 0.26
atpE 1461189 c.145C>T synonymous_variant 0.18
atpE 1461194 c.150C>T synonymous_variant 0.2
atpE 1461197 c.153A>G synonymous_variant 0.14
atpE 1461219 c.175T>C synonymous_variant 0.27
atpE 1461224 c.180T>C synonymous_variant 0.28
atpE 1461233 c.189A>G synonymous_variant 0.27
atpE 1461254 c.210T>C synonymous_variant 0.21
atpE 1461275 c.231T>C synonymous_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.14
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.16
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.17
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.16
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.17
rrs 1472044 n.199G>C non_coding_transcript_exon_variant 0.14
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.15
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.15
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.28
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.27
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.38
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.28
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.2
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.2
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.18
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.17
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.21
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.3
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.33
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.35
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.14
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.17
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.17
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.18
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.13
rrl 1474051 n.394T>C non_coding_transcript_exon_variant 0.18
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.18
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.23
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.25
rrl 1474104 n.447G>A non_coding_transcript_exon_variant 0.24
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.23
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.23
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.35
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.26
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.26
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.36
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.33
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.26
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.24
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.16
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.19
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.2
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.22
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.21
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.21
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.2
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.17
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.16
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.17
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.35
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.35
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.24
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.19
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.18
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.14
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.26
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.17
rrl 1476025 n.2368G>T non_coding_transcript_exon_variant 0.18
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.16
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.15
rrl 1476033 n.2376T>C non_coding_transcript_exon_variant 0.15
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.15
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.19
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.19
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.2
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.16
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.17
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.17
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.23
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.14
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.22
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.24
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.35
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.31
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.35
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.2
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.2
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.19
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.23
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.29
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.26
rrl 1476725 n.3068C>T non_coding_transcript_exon_variant 0.26
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.26
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.41
rrl 1476755 n.3098G>A non_coding_transcript_exon_variant 0.38
rrl 1476759 n.3102T>C non_coding_transcript_exon_variant 0.35
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.25
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.25
rrl 1476790 n.3134dupC non_coding_transcript_exon_variant 0.13
inhA 1674205 p.Thr2Ala missense_variant 0.14
inhA 1674231 c.30T>C synonymous_variant 0.19
inhA 1674237 c.36T>C synonymous_variant 0.16
inhA 1674239 p.Ser13Thr missense_variant 0.17
inhA 1674243 c.42A>G synonymous_variant 0.16
inhA 1674321 c.120G>C synonymous_variant 0.14
inhA 1674342 c.141T>C synonymous_variant 0.2
inhA 1674352 p.Thr51Val missense_variant 0.2
inhA 1674368 p.Ala56Glu missense_variant 0.13
inhA 1674537 c.336C>G synonymous_variant 0.14
inhA 1674654 c.453G>C synonymous_variant 0.16
inhA 1674693 c.492C>G synonymous_variant 0.16
rpsA 1833554 p.Thr5Ala missense_variant 0.14
rpsA 1833568 c.27G>C synonymous_variant 0.24
rpsA 1833589 c.48A>T synonymous_variant 0.2
rpsA 1833595 c.54T>C synonymous_variant 0.19
rpsA 1833619 c.78A>C synonymous_variant 0.18
rpsA 1833724 c.183C>G synonymous_variant 0.17
rpsA 1833727 c.186G>C synonymous_variant 0.16
rpsA 1833742 c.201A>G synonymous_variant 0.19
rpsA 1833745 c.204G>C synonymous_variant 0.2
rpsA 1833787 c.246C>G synonymous_variant 0.22
rpsA 1833790 c.249T>A synonymous_variant 0.17
rpsA 1833799 c.258C>G synonymous_variant 0.18
rpsA 1833928 c.387G>C synonymous_variant 0.19
rpsA 1833940 c.399C>G synonymous_variant 0.23
rpsA 1833970 c.429G>C synonymous_variant 0.23
rpsA 1833979 c.438T>C synonymous_variant 0.19
rpsA 1834000 c.459G>C synonymous_variant 0.21
rpsA 1834015 c.474G>C synonymous_variant 0.16
rpsA 1834021 c.480C>T synonymous_variant 0.17
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.21
rpsA 1834102 c.561T>C synonymous_variant 0.19
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834186 c.645C>G synonymous_variant 0.15
rpsA 1834189 c.648G>C synonymous_variant 0.16
rpsA 1834195 c.654G>C synonymous_variant 0.15
rpsA 1834225 c.684C>G synonymous_variant 0.18
rpsA 1834240 c.699T>C synonymous_variant 0.15
rpsA 1834249 c.708T>C synonymous_variant 0.15
rpsA 1834261 c.720A>C synonymous_variant 0.24
rpsA 1834264 c.723G>C synonymous_variant 0.24
rpsA 1834297 c.756C>G synonymous_variant 0.4
rpsA 1834303 c.762T>G synonymous_variant 0.38
rpsA 1834306 c.765T>C synonymous_variant 0.38
rpsA 1834348 c.807T>C synonymous_variant 0.35
rpsA 1834366 c.825A>G synonymous_variant 0.32
rpsA 1834375 c.834G>A synonymous_variant 0.28
rpsA 1834396 c.855G>C synonymous_variant 0.3
rpsA 1834411 c.870T>C synonymous_variant 0.27
rpsA 1834417 c.876G>C synonymous_variant 0.25
rpsA 1834423 c.882G>C synonymous_variant 0.31
rpsA 1834435 c.894G>C synonymous_variant 0.24
rpsA 1834451 c.910T>C synonymous_variant 0.14
rpsA 1834498 c.957C>T synonymous_variant 0.14
rpsA 1834528 c.987T>C synonymous_variant 0.21
rpsA 1834546 c.1005T>C synonymous_variant 0.22
rpsA 1834555 c.1014T>C synonymous_variant 0.24
rpsA 1834558 c.1017C>G synonymous_variant 0.26
rpsA 1834609 c.1068T>C synonymous_variant 0.17
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.16
rpsA 1834633 c.1092A>G synonymous_variant 0.19
rpsA 1834639 c.1098T>C synonymous_variant 0.26
rpsA 1834666 c.1125G>C synonymous_variant 0.3
rpsA 1834669 c.1128G>C synonymous_variant 0.34
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.23
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918008 c.69C>A synonymous_variant 0.18
ndh 2101924 c.1119T>G synonymous_variant 0.15
ndh 2101939 c.1104A>C synonymous_variant 0.17
ndh 2101960 c.1083A>G synonymous_variant 0.19
ndh 2101966 c.1077T>G synonymous_variant 0.16
ndh 2101972 c.1071G>C synonymous_variant 0.16
ndh 2101978 p.Asn355Asp missense_variant 0.18
ndh 2101988 p.Ala352Gly missense_variant 0.2
ndh 2102009 p.Ser345Asn missense_variant 0.16
ndh 2102026 c.1017G>C synonymous_variant 0.13
ndh 2102242 c.801G>A synonymous_variant 0.16
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155590 c.522A>G synonymous_variant 0.16
katG 2155614 p.Val166Ile missense_variant 0.16
katG 2155617 c.495T>C synonymous_variant 0.16
katG 2155632 c.480A>C synonymous_variant 0.28
katG 2155637 p.Leu159Ile missense_variant 0.28
katG 2155641 p.Lys157Asn missense_variant 0.26
katG 2155677 c.435C>G synonymous_variant 0.36
katG 2155680 c.432G>C synonymous_variant 0.31
katG 2155696 p.Ala139Val missense_variant 0.13
katG 2155716 c.396T>C synonymous_variant 0.13
katG 2155719 c.393G>C synonymous_variant 0.12
katG 2155722 c.390G>C synonymous_variant 0.12
katG 2155740 p.Gly124Gln missense_variant 0.14
katG 2155747 p.Ala122Gly missense_variant 0.17
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 0.95
kasA 2517974 c.-141T>C upstream_gene_variant 0.24
kasA 2517989 c.-126T>C upstream_gene_variant 0.23
kasA 2517992 c.-123C>G upstream_gene_variant 0.17
kasA 2518504 c.390T>C synonymous_variant 0.13
kasA 2518506 p.Ala131Glu missense_variant 0.12
kasA 2518519 c.405G>C synonymous_variant 0.2
kasA 2518528 c.414C>G synonymous_variant 0.21
kasA 2518540 c.426T>G synonymous_variant 0.17
kasA 2518663 c.549T>C synonymous_variant 0.17
kasA 2518672 c.558G>C synonymous_variant 0.17
kasA 2518696 c.582C>G synonymous_variant 0.2
kasA 2518702 c.588C>T synonymous_variant 0.18
kasA 2518768 c.654C>G synonymous_variant 0.21
kasA 2518783 c.669T>C synonymous_variant 0.22
kasA 2518792 c.678C>G synonymous_variant 0.21
kasA 2518795 c.681C>G synonymous_variant 0.15
kasA 2518822 c.708C>G synonymous_variant 0.21
kasA 2518825 c.711T>C synonymous_variant 0.22
kasA 2519027 p.Ile305Val missense_variant 0.12
kasA 2519053 c.939G>C synonymous_variant 0.18
kasA 2519062 c.948T>G synonymous_variant 0.18
kasA 2519068 c.954C>T synonymous_variant 0.25
kasA 2519072 p.Ala320Thr missense_variant 0.25
kasA 2519077 c.963G>C synonymous_variant 0.22
kasA 2519146 c.1032C>A synonymous_variant 0.13
kasA 2519167 c.1053T>C synonymous_variant 0.19
kasA 2519173 c.1059C>G synonymous_variant 0.19
kasA 2519176 c.1062G>A synonymous_variant 0.19
ahpC 2726372 c.180G>C synonymous_variant 0.17
ahpC 2726378 c.186T>C synonymous_variant 0.2
ahpC 2726391 p.Ala67Thr missense_variant 0.12
ahpC 2726657 c.465A>C synonymous_variant 0.14
folC 2746468 c.1131G>T synonymous_variant 0.17
folC 2747059 c.540T>C synonymous_variant 0.14
folC 2747065 c.534C>G synonymous_variant 0.14
folC 2747086 c.513A>C synonymous_variant 0.15
folC 2747089 c.510G>C synonymous_variant 0.19
folC 2747355 p.Val82Ile missense_variant 0.24
folC 2747359 c.240C>G synonymous_variant 0.23
folC 2747362 c.237G>C synonymous_variant 0.22
folC 2747578 c.21C>A synonymous_variant 0.22
Rv2752c 3064815 c.1377T>C synonymous_variant 0.25
Rv2752c 3064831 p.Ala454Asp missense_variant 0.29
Rv2752c 3064835 p.Ile453Val missense_variant 0.29
Rv2752c 3064838 c.1354T>C synonymous_variant 0.31
Rv2752c 3064860 c.1332G>C synonymous_variant 0.24
Rv2752c 3064872 c.1320T>G synonymous_variant 0.16
Rv2752c 3065064 c.1128G>C synonymous_variant 0.17
Rv2752c 3065073 c.1119C>G synonymous_variant 0.17
Rv2752c 3066066 c.126T>C synonymous_variant 0.16
Rv2752c 3066075 c.117A>G synonymous_variant 0.27
Rv2752c 3066087 c.105A>G synonymous_variant 0.28
Rv2752c 3066118 p.Asn25Ser missense_variant 0.22
thyX 3067610 p.Lys112Asn missense_variant 0.23
thyX 3067613 c.333G>A synonymous_variant 0.25
thyX 3067619 c.327A>C synonymous_variant 0.32
thyX 3067640 c.306G>C synonymous_variant 0.32
thyX 3067643 c.303C>T synonymous_variant 0.3
thyX 3067652 c.294T>C synonymous_variant 0.37
thyX 3067661 c.285C>G synonymous_variant 0.33
thyX 3067682 c.264G>C synonymous_variant 0.17
thyX 3067739 c.207T>C synonymous_variant 0.14
thyX 3067787 c.159G>A synonymous_variant 0.12
thyX 3067793 c.153T>C synonymous_variant 0.12
thyX 3067814 c.132T>C synonymous_variant 0.17
thyX 3067826 c.120C>G synonymous_variant 0.19
thyX 3067850 c.96A>C synonymous_variant 0.16
thyA 3073812 c.660C>G synonymous_variant 0.21
thyA 3073824 c.648A>C synonymous_variant 0.19
thyA 3073827 c.645A>G synonymous_variant 0.17
thyA 3073863 c.609T>C synonymous_variant 0.2
thyA 3073872 p.Ile200Val missense_variant 0.21
thyA 3073878 c.594G>A synonymous_variant 0.24
thyA 3073892 c.580T>C synonymous_variant 0.3
thyA 3073893 c.579C>G synonymous_variant 0.32
thyA 3073902 c.570C>G synonymous_variant 0.31
thyA 3073925 c.547T>C synonymous_variant 0.15
thyA 3073926 c.546G>C synonymous_variant 0.15
thyA 3073929 c.543T>C synonymous_variant 0.18
thyA 3073953 c.519T>C synonymous_variant 0.16
thyA 3073977 c.495A>G synonymous_variant 0.2
thyA 3073989 c.483T>C synonymous_variant 0.21
thyA 3074001 c.471C>G synonymous_variant 0.17
thyA 3074004 c.468T>C synonymous_variant 0.19
thyA 3074010 c.462C>G synonymous_variant 0.18
thyA 3074031 c.441T>C synonymous_variant 0.2
thyA 3074037 c.435C>G synonymous_variant 0.17
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339040 c.-78T>C upstream_gene_variant 1.0
fprA 3473809 c.-198G>C upstream_gene_variant 0.19
fprA 3473812 c.-195G>A upstream_gene_variant 0.18
fprA 3473836 c.-171C>A upstream_gene_variant 0.21
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
fbiA 3640347 c.-196A>G upstream_gene_variant 0.18
alr 3840248 c.1173C>G synonymous_variant 0.13
rpoA 3877515 c.993G>C synonymous_variant 0.14
rpoA 3877553 p.Glu319Gln missense_variant 0.19
rpoA 3877557 c.951C>G synonymous_variant 0.2
rpoA 3877587 c.921A>G synonymous_variant 0.3
rpoA 3877613 p.Ile299Val missense_variant 0.38
rpoA 3877638 c.870T>C synonymous_variant 0.27
rpoA 3877656 c.852T>C synonymous_variant 0.26
rpoA 3877668 c.840A>G synonymous_variant 0.14
rpoA 3877905 c.603A>G synonymous_variant 0.13
rpoA 3877962 c.546G>T synonymous_variant 0.33
rpoA 3877986 c.522G>C synonymous_variant 0.32
rpoA 3877989 c.519A>G synonymous_variant 0.3
rpoA 3878001 c.507A>G synonymous_variant 0.3
rpoA 3878082 c.426T>C synonymous_variant 0.19
rpoA 3878094 c.414C>G synonymous_variant 0.17
rpoA 3878100 c.408C>G synonymous_variant 0.15
rpoA 3878103 c.405A>G synonymous_variant 0.15
rpoA 3878106 c.402G>C synonymous_variant 0.16
rpoA 3878118 c.390T>C synonymous_variant 0.17
rpoA 3878217 c.291A>G synonymous_variant 0.18
rpoA 3878220 c.288C>T synonymous_variant 0.14
rpoA 3878271 c.237T>C synonymous_variant 0.19
rpoA 3878284 p.Glu75Ala missense_variant 0.16
rpoA 3878292 c.216T>C synonymous_variant 0.18
rpoA 3878298 c.210A>G synonymous_variant 0.19
rpoA 3878304 c.204G>C synonymous_variant 0.13
rpoA 3878313 c.195G>C synonymous_variant 0.19
rpoA 3878376 c.132G>C synonymous_variant 0.17
rpoA 3878385 c.123C>G synonymous_variant 0.25
rpoA 3878391 c.117T>C synonymous_variant 0.16
rpoA 3878396 c.112C>T synonymous_variant 0.15
clpC1 4038271 p.Pro812Ala missense_variant 0.23
clpC1 4038272 p.Gly811Ser missense_variant 0.25
clpC1 4038278 c.2427T>C synonymous_variant 0.23
clpC1 4038293 c.2412G>C synonymous_variant 0.27
clpC1 4038302 c.2403C>G synonymous_variant 0.19
clpC1 4038308 p.Val799Ile missense_variant 0.17
clpC1 4038317 c.2388G>C synonymous_variant 0.19
clpC1 4038347 c.2358G>C synonymous_variant 0.18
clpC1 4038359 c.2346A>G synonymous_variant 0.17
clpC1 4038368 c.2337T>C synonymous_variant 0.19
clpC1 4038461 c.2244G>C synonymous_variant 0.12
clpC1 4038498 p.Ser736Thr missense_variant 0.18
clpC1 4038530 p.Glu725Asp missense_variant 0.15
clpC1 4038536 c.2169C>T synonymous_variant 0.2
clpC1 4038596 c.2109A>G synonymous_variant 0.2
clpC1 4038611 c.2094C>T synonymous_variant 0.12
clpC1 4038640 p.Asp689Asn missense_variant 0.17
clpC1 4038740 c.1965G>C synonymous_variant 0.2
clpC1 4038755 c.1950G>C synonymous_variant 0.25
clpC1 4038773 c.1932T>C synonymous_variant 0.35
clpC1 4038782 c.1923G>C synonymous_variant 0.33
clpC1 4038790 c.1915C>T synonymous_variant 0.37
clpC1 4038812 c.1893T>C synonymous_variant 0.25
clpC1 4038815 c.1890G>T synonymous_variant 0.25
clpC1 4038851 c.1854G>A synonymous_variant 0.22
clpC1 4038878 c.1827A>G synonymous_variant 0.25
clpC1 4038908 c.1797C>G synonymous_variant 0.16
clpC1 4038914 c.1791G>C synonymous_variant 0.14
clpC1 4039022 c.1683A>G synonymous_variant 0.15
clpC1 4039025 c.1680C>T synonymous_variant 0.81
clpC1 4039073 c.1632C>G synonymous_variant 0.14
clpC1 4039364 c.1341C>G synonymous_variant 0.12
clpC1 4039463 c.1242C>G synonymous_variant 0.15
clpC1 4039469 c.1236T>C synonymous_variant 0.16
clpC1 4039481 c.1224T>G synonymous_variant 0.16
clpC1 4039484 c.1221T>G synonymous_variant 0.16
clpC1 4039517 c.1188C>G synonymous_variant 0.14
clpC1 4039547 c.1158C>G synonymous_variant 0.14
clpC1 4039553 c.1152C>G synonymous_variant 0.14
clpC1 4039562 c.1143C>G synonymous_variant 0.12
clpC1 4039565 c.1140G>C synonymous_variant 0.14
clpC1 4039576 p.Ala377Ser missense_variant 0.14
clpC1 4039577 c.1128T>C synonymous_variant 0.14
clpC1 4039586 c.1119G>C synonymous_variant 0.17
clpC1 4039610 c.1095G>C synonymous_variant 0.21
clpC1 4039616 c.1089G>C synonymous_variant 0.18
clpC1 4039622 c.1083C>G synonymous_variant 0.22
clpC1 4039685 c.1020C>T synonymous_variant 0.15
clpC1 4039898 c.807C>G synonymous_variant 0.13
clpC1 4039904 c.801A>G synonymous_variant 0.19
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.17
clpC1 4039931 c.774T>C synonymous_variant 0.2
clpC1 4039946 c.759A>T synonymous_variant 0.18
clpC1 4039952 c.753T>C synonymous_variant 0.17
clpC1 4039958 c.747G>C synonymous_variant 0.22
clpC1 4039996 p.Glu237Gln missense_variant 0.18
clpC1 4040021 c.684A>C synonymous_variant 0.23
clpC1 4040024 c.681A>G synonymous_variant 0.2
clpC1 4040033 c.672G>C synonymous_variant 0.23
clpC1 4040036 c.669C>G synonymous_variant 0.23
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.14
clpC1 4040093 c.612C>G synonymous_variant 0.14
clpC1 4040105 c.600C>G synonymous_variant 0.19
clpC1 4040354 c.351A>G synonymous_variant 0.17
clpC1 4040363 c.342A>C synonymous_variant 0.18
clpC1 4040369 c.336C>G synonymous_variant 0.16
clpC1 4040459 c.246C>G synonymous_variant 0.17
clpC1 4040477 c.228G>A synonymous_variant 0.17
clpC1 4040480 c.225T>C synonymous_variant 0.15
panD 4044150 c.132A>G synonymous_variant 0.12
panD 4044162 c.120A>G synonymous_variant 0.15
panD 4044165 c.117G>C synonymous_variant 0.17
panD 4044188 c.94T>C synonymous_variant 0.15
embC 4240258 c.396T>G synonymous_variant 0.14
embC 4240388 p.Asn176His missense_variant 0.18
embC 4240632 p.Met257Thr missense_variant 0.18
embC 4240642 c.780G>C synonymous_variant 0.25
embC 4240645 c.783G>C synonymous_variant 0.23
embC 4240657 c.795G>C synonymous_variant 0.36
embC 4240671 p.Thr270Ile missense_variant 0.17
embC 4240726 c.864G>C synonymous_variant 0.17
embC 4240780 c.918T>C synonymous_variant 0.22
embC 4240783 c.921G>C synonymous_variant 0.19
embC 4240789 c.927T>C synonymous_variant 0.17
embC 4240819 c.957A>G synonymous_variant 0.16
embC 4240825 c.963G>A synonymous_variant 0.15
embC 4240831 c.969T>G synonymous_variant 0.15
embC 4241443 c.1581C>G synonymous_variant 0.21
embA 4242427 c.-806A>C upstream_gene_variant 0.3
embC 4242428 p.Ala856Ser missense_variant 0.3
embC 4242434 p.Val858Ile missense_variant 0.27
embC 4242449 p.Met863His missense_variant 0.17
embA 4242460 c.-773G>C upstream_gene_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4244525 c.1293G>A synonymous_variant 0.18
embA 4245077 c.1845G>C synonymous_variant 0.17
embA 4245083 c.1851A>C synonymous_variant 0.19
embA 4245089 c.1857G>C synonymous_variant 0.18
embA 4245092 c.1860C>G synonymous_variant 0.2
embA 4245101 c.1869G>C synonymous_variant 0.17
embA 4245137 c.1905T>C synonymous_variant 0.17
embA 4245149 c.1917C>G synonymous_variant 0.17
embB 4247401 c.888T>C synonymous_variant 0.14
embB 4247437 c.924A>G synonymous_variant 0.15
embB 4247440 c.927C>G synonymous_variant 0.19
embB 4247464 c.951C>G synonymous_variant 0.14
embB 4247470 c.957T>C synonymous_variant 0.15
embB 4247491 c.978G>C synonymous_variant 0.2
embB 4247497 c.984T>C synonymous_variant 0.18
embB 4247500 c.987C>G synonymous_variant 0.18
embB 4247776 c.1263G>T synonymous_variant 0.18
embB 4247800 c.1287A>C synonymous_variant 0.14
embB 4247806 c.1293G>C synonymous_variant 0.13
embB 4247951 p.Ser480Ala missense_variant 0.17
embB 4247956 c.1443G>C synonymous_variant 0.15
embB 4247974 c.1461C>G synonymous_variant 0.21
embB 4247977 c.1464C>G synonymous_variant 0.23
embB 4247986 c.1473C>G synonymous_variant 0.2
embB 4248007 c.1494C>G synonymous_variant 0.15
embB 4248011 p.Ser500Ala missense_variant 0.15
embB 4248118 c.1605T>C synonymous_variant 0.14
embB 4248142 c.1629T>C synonymous_variant 0.16
embB 4248143 c.1630T>C synonymous_variant 0.16
embB 4248206 p.Ser565Gly missense_variant 0.14
embB 4248220 c.1707A>G synonymous_variant 0.21
embB 4248241 c.1728C>T synonymous_variant 0.19
embB 4248265 c.1752C>T synonymous_variant 0.18
embB 4248266 c.1753C>T synonymous_variant 0.17
embB 4248277 c.1764G>C synonymous_variant 0.17
embB 4248902 p.Thr797Pro missense_variant 1.0
embB 4249381 c.2868A>G synonymous_variant 0.14
embB 4249423 p.Asp970Glu missense_variant 0.12
embB 4249424 p.Leu971Met missense_variant 0.13
embB 4249432 c.2919A>G synonymous_variant 0.13
aftB 4267556 c.1281G>C synonymous_variant 0.27
aftB 4267571 c.1266T>C synonymous_variant 0.27
aftB 4267580 c.1257G>C synonymous_variant 0.27
aftB 4267607 c.1230G>A synonymous_variant 0.29
aftB 4267619 c.1218C>G synonymous_variant 0.19
aftB 4267625 c.1212T>C synonymous_variant 0.14
aftB 4267634 p.Arg401His missense_variant 0.14
aftB 4267637 c.1200C>G synonymous_variant 0.17
aftB 4267647 p.Asp397Gly missense_variant 0.83
aftB 4267649 c.1188T>C synonymous_variant 0.17
aftB 4267688 c.1149G>T synonymous_variant 0.14
ubiA 4269828 c.4_5dupAG frameshift_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 1.0