Run ID: SRR21732954
Sample name:
Date: 18-01-2024 14:45:11
Number of reads: 6017
Percentage reads mapped: 42.57
Strain: lineage4.9
Drug-resistance: Sensitive
| Drug | Resistance | Supporting mutations |
|---|---|---|
| Rifampicin | ||
| Isoniazid | ||
| Ethambutol | ||
| Pyrazinamide | ||
| Streptomycin | ||
| Fluoroquinolones | ||
| Moxifloxacin | ||
| Ofloxacin | ||
| Levofloxacin | ||
| Ciprofloxacin | ||
| Aminoglycosides | ||
| Amikacin | ||
| Capreomycin | ||
| Kanamycin | ||
| Cycloserine | ||
| Ethionamide | ||
| Clofazimine | ||
| Para-aminosalicylic_acid | ||
| Delamanid | ||
| Bedaquiline | ||
| Linezolid |
| Lineage | Family | Main Spoligotype | RDs | Frequency |
|---|---|---|---|---|
| lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
| lineage4.9 | Euro-American (H37Rv-like) | T1 | None | 0.98 |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction |
|---|---|---|---|---|
| rpoB | 760919 | c.1113C>G | synonymous_variant | 1.0 |
| rpoB | 760925 | c.1119T>C | synonymous_variant | 1.0 |
| rpoB | 760928 | c.1122G>C | synonymous_variant | 0.92 |
| rpoB | 760934 | c.1128C>T | synonymous_variant | 1.0 |
| rpoB | 760946 | c.1140A>G | synonymous_variant | 1.0 |
| rpoB | 760970 | c.1164G>C | synonymous_variant | 1.0 |
| rpoB | 760982 | c.1176G>C | synonymous_variant | 1.0 |
| rpoB | 760985 | c.1179G>C | synonymous_variant | 1.0 |
| rpoB | 760991 | c.1185G>C | synonymous_variant | 1.0 |
| rpoB | 761537 | c.1731C>G | synonymous_variant | 1.0 |
| rpoB | 761570 | c.1764T>C | synonymous_variant | 1.0 |
| rpoB | 761573 | c.1767C>G | synonymous_variant | 1.0 |
| rpoB | 761579 | c.1773G>C | synonymous_variant | 1.0 |
| rpoB | 761606 | c.1800C>G | synonymous_variant | 1.0 |
| rpoB | 761612 | c.1806G>C | synonymous_variant | 1.0 |
| rpoB | 761615 | c.1809A>C | synonymous_variant | 1.0 |
| rpoB | 761636 | c.1830G>T | synonymous_variant | 1.0 |
| rpoB | 761645 | c.1839C>G | synonymous_variant | 1.0 |
| rpoB | 761648 | c.1842T>C | synonymous_variant | 1.0 |
| rpoB | 761657 | c.1851C>G | synonymous_variant | 1.0 |
| rpoC | 764011 | c.642T>C | synonymous_variant | 1.0 |
| rpoC | 764024 | c.655T>C | synonymous_variant | 1.0 |
| rpoC | 764040 | p.Ser224Asn | missense_variant | 1.0 |
| rpoC | 764044 | c.675T>C | synonymous_variant | 1.0 |
| rpoC | 764059 | c.690G>C | synonymous_variant | 1.0 |
| rpoC | 764083 | c.714A>G | synonymous_variant | 1.0 |
| rpoC | 764098 | c.729A>G | synonymous_variant | 1.0 |
| rpoC | 764101 | c.732C>G | synonymous_variant | 1.0 |
| rpoC | 764110 | c.741C>T | synonymous_variant | 1.0 |
| rpoC | 764131 | c.762T>C | synonymous_variant | 1.0 |
| rpoC | 764161 | c.792G>C | synonymous_variant | 1.0 |
| rpoC | 764365 | c.996C>T | synonymous_variant | 1.0 |
| rpoC | 764380 | c.1011G>C | synonymous_variant | 1.0 |
| rpoC | 764381 | c.1012_1013delTCinsAG | synonymous_variant | 1.0 |
| rpoC | 764387 | c.1018_1020delTTGinsCTC | synonymous_variant | 1.0 |
| rpoC | 764405 | c.1036A>C | synonymous_variant | 1.0 |
| rpoC | 764431 | c.1062G>C | synonymous_variant | 1.0 |
| rpoC | 764434 | c.1065A>G | synonymous_variant | 1.0 |
| rpoC | 764446 | c.1077T>C | synonymous_variant | 1.0 |
| rpoC | 764449 | c.1080G>C | synonymous_variant | 1.0 |
| rpoC | 764452 | c.1083T>C | synonymous_variant | 1.0 |
| rpoC | 764458 | c.1089G>C | synonymous_variant | 1.0 |
| rpoC | 764461 | c.1092A>G | synonymous_variant | 1.0 |
| rpoC | 764497 | c.1128A>G | synonymous_variant | 1.0 |
| rpoC | 764503 | c.1134G>C | synonymous_variant | 1.0 |
| rpoC | 764521 | c.1152T>C | synonymous_variant | 1.0 |
| rpoC | 764536 | c.1167G>C | synonymous_variant | 1.0 |
| rpoC | 764539 | c.1170C>G | synonymous_variant | 1.0 |
| rpoC | 764695 | c.1326T>C | synonymous_variant | 1.0 |
| rpoC | 764716 | c.1347G>C | synonymous_variant | 1.0 |
| rpoC | 764752 | c.1383G>C | synonymous_variant | 1.0 |
| rpoC | 764764 | c.1395T>C | synonymous_variant | 1.0 |
| rpoC | 764791 | c.1422C>G | synonymous_variant | 1.0 |
| rpoC | 764809 | c.1440C>T | synonymous_variant | 1.0 |
| rpoC | 764812 | c.1443C>G | synonymous_variant | 1.0 |
| rpoC | 764815 | c.1446A>G | synonymous_variant | 1.0 |
| rpoC | 764824 | c.1455T>C | synonymous_variant | 1.0 |
| rpoC | 764830 | c.1461C>G | synonymous_variant | 1.0 |
| rpoC | 766645 | c.3276A>G | synonymous_variant | 1.0 |
| rpoC | 766651 | c.3282T>C | synonymous_variant | 1.0 |
| rpoC | 766657 | c.3288A>G | synonymous_variant | 1.0 |
| rpoC | 766672 | c.3303T>C | synonymous_variant | 1.0 |
| rpoC | 766726 | c.3357T>C | synonymous_variant | 1.0 |
| rpoC | 766738 | c.3369G>T | synonymous_variant | 1.0 |
| rpoC | 766750 | c.3381C>G | synonymous_variant | 1.0 |
| rpoC | 766765 | c.3396A>C | synonymous_variant | 1.0 |
| rpoC | 766774 | c.3405T>C | synonymous_variant | 1.0 |
| rpoC | 766804 | c.3435A>G | synonymous_variant | 1.0 |
| rpoC | 766861 | c.3492G>C | synonymous_variant | 1.0 |
| rpoC | 766864 | c.3495G>C | synonymous_variant | 1.0 |
| rpsL | 781736 | c.177T>C | synonymous_variant | 1.0 |
| rpsL | 781793 | c.234G>C | synonymous_variant | 1.0 |
| rpsL | 781832 | c.273T>C | synonymous_variant | 1.0 |
| rpsL | 781841 | c.282C>G | synonymous_variant | 1.0 |
| rpsL | 781859 | c.300T>C | synonymous_variant | 1.0 |
| rpsL | 781868 | c.309T>C | synonymous_variant | 1.0 |
| rpsL | 781871 | c.312G>C | synonymous_variant | 1.0 |
| rpsL | 781892 | c.333A>G | synonymous_variant | 1.0 |
| rpsL | 781898 | c.339A>T | synonymous_variant | 1.0 |
| rpsL | 781916 | c.357T>C | synonymous_variant | 1.0 |
| rpsL | 781929 | p.Gly124Ser | missense_variant | 1.0 |
| rpsA | 1833811 | c.270G>C | synonymous_variant | 1.0 |
| rpsA | 1833838 | c.297G>C | synonymous_variant | 1.0 |
| rpsA | 1833841 | c.300C>G | synonymous_variant | 1.0 |
| rpsA | 1833847 | c.306C>G | synonymous_variant | 1.0 |
| rpsA | 1833856 | c.315A>G | synonymous_variant | 1.0 |
| rpsA | 1833862 | c.321G>T | synonymous_variant | 1.0 |
| rpsA | 1833874 | c.333T>C | synonymous_variant | 1.0 |
| rpsA | 1833928 | c.387G>C | synonymous_variant | 0.98 |
| rpsA | 1833940 | c.399C>G | synonymous_variant | 1.0 |
| rpsA | 1833970 | c.429G>C | synonymous_variant | 1.0 |
| rpsA | 1833979 | c.438T>C | synonymous_variant | 1.0 |
| rpsA | 1834000 | c.459G>C | synonymous_variant | 1.0 |
| rpsA | 1834015 | c.474G>C | synonymous_variant | 1.0 |
| rpsA | 1834021 | c.480C>T | synonymous_variant | 1.0 |
| rpsA | 1834222 | c.681T>C | synonymous_variant | 1.0 |
| rpsA | 1834225 | c.684C>G | synonymous_variant | 1.0 |
| rpsA | 1834240 | c.699T>C | synonymous_variant | 1.0 |
| rpsA | 1834249 | c.708T>C | synonymous_variant | 1.0 |
| rpsA | 1834261 | c.720A>C | synonymous_variant | 1.0 |
| rpoA | 3877613 | p.Ile299Val | missense_variant | 1.0 |
| rpoA | 3877638 | c.870T>C | synonymous_variant | 1.0 |
| rpoA | 3877656 | c.852T>C | synonymous_variant | 1.0 |
| rpoA | 3877668 | c.840A>G | synonymous_variant | 1.0 |
| rpoA | 3877677 | p.Ala277Ser | missense_variant | 1.0 |
| rpoA | 3877680 | c.828G>C | synonymous_variant | 1.0 |
| rpoA | 3877686 | c.822A>G | synonymous_variant | 1.0 |
| rpoA | 3877692 | c.816G>C | synonymous_variant | 1.0 |
| rpoA | 3877704 | c.804G>T | synonymous_variant | 0.95 |
| rpoA | 3877743 | c.765T>C | synonymous_variant | 1.0 |
| rpoA | 3877764 | c.744C>G | synonymous_variant | 1.0 |
| rpoA | 3877770 | c.738A>G | synonymous_variant | 1.0 |
| rpoA | 3877776 | c.732T>C | synonymous_variant | 1.0 |
| rpoA | 3877782 | c.726T>C | synonymous_variant | 1.0 |
| rpoA | 3877818 | c.690A>G | synonymous_variant | 1.0 |
| rpoA | 3877839 | c.669G>C | synonymous_variant | 1.0 |
| rpoA | 3877857 | c.651G>A | synonymous_variant | 1.0 |
| rpoA | 3877866 | c.642G>C | synonymous_variant | 1.0 |
| clpC1 | 4038596 | c.2109A>G | synonymous_variant | 1.0 |
| clpC1 | 4038623 | c.2082A>G | synonymous_variant | 1.0 |
| clpC1 | 4038640 | p.Asp689Asn | missense_variant | 1.0 |
| clpC1 | 4038653 | c.2052C>T | synonymous_variant | 1.0 |
| clpC1 | 4038658 | p.Lys683Gln | missense_variant | 1.0 |
| clpC1 | 4038661 | p.Ser682Thr | missense_variant | 1.0 |
| clpC1 | 4038662 | c.2043T>C | synonymous_variant | 1.0 |
| clpC1 | 4038671 | c.2034T>C | synonymous_variant | 1.0 |
| clpC1 | 4038683 | c.2022T>C | synonymous_variant | 1.0 |
| clpC1 | 4038695 | c.2010C>G | synonymous_variant | 1.0 |
| clpC1 | 4038701 | c.2004G>C | synonymous_variant | 1.0 |
| clpC1 | 4038704 | c.2001T>C | synonymous_variant | 1.0 |
| clpC1 | 4038707 | c.1998C>G | synonymous_variant | 1.0 |
| clpC1 | 4038710 | c.1995G>C | synonymous_variant | 1.0 |
| clpC1 | 4038713 | c.1992T>C | synonymous_variant | 1.0 |
| clpC1 | 4038740 | c.1965G>C | synonymous_variant | 1.0 |
| clpC1 | 4038755 | c.1950G>C | synonymous_variant | 1.0 |
| clpC1 | 4038773 | c.1932T>C | synonymous_variant | 1.0 |
| clpC1 | 4038782 | c.1923G>C | synonymous_variant | 1.0 |
| clpC1 | 4038790 | c.1915C>T | synonymous_variant | 1.0 |
| clpC1 | 4038812 | c.1893T>C | synonymous_variant | 1.0 |
| clpC1 | 4038815 | c.1890G>T | synonymous_variant | 0.97 |
| clpC1 | 4038878 | c.1827A>G | synonymous_variant | 1.0 |
| clpC1 | 4038908 | c.1797C>G | synonymous_variant | 1.0 |
| clpC1 | 4038914 | c.1791G>C | synonymous_variant | 1.0 |
| clpC1 | 4038923 | c.1782A>G | synonymous_variant | 1.0 |
| clpC1 | 4038932 | c.1773G>C | synonymous_variant | 1.0 |
| clpC1 | 4039142 | c.1563A>G | synonymous_variant | 1.0 |
| clpC1 | 4039145 | c.1560G>C | synonymous_variant | 1.0 |
| clpC1 | 4039169 | p.Glu512Asp | missense_variant | 1.0 |
| clpC1 | 4039172 | c.1533A>G | synonymous_variant | 1.0 |
| clpC1 | 4039178 | c.1527G>C | synonymous_variant | 1.0 |
| clpC1 | 4039183 | c.1522T>C | synonymous_variant | 1.0 |
| clpC1 | 4039187 | c.1518G>C | synonymous_variant | 1.0 |
| clpC1 | 4039190 | c.1515C>G | synonymous_variant | 1.0 |
| clpC1 | 4039208 | c.1497C>G | synonymous_variant | 1.0 |
| clpC1 | 4039226 | c.1479T>C | synonymous_variant | 1.0 |
| clpC1 | 4039268 | c.1437C>G | synonymous_variant | 1.0 |
| clpC1 | 4039274 | c.1431G>C | synonymous_variant | 1.0 |
