TB-Profiler result

Run: ERR1198988
Summary

Run ID: ERR1198988

Sample name:

Date: 15-08-2022 10:05:24

Number of reads: 2240439

Percentage reads mapped: 14.63

Strain: lineage4.6.1.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.1 Euro-American (Uganda) T2 RD724 1.0
lineage4.6.1.1 Euro-American T2-Uganda RD724 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7539 p.Thr80Ala missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9286 p.Ala662Val missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 762836 c.-534C>G upstream_gene_variant 0.21
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416232 p.Cys372Gly missense_variant 0.1
embR 1416259 c.1089G>C synonymous_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.76
rrs 1471900 n.55C>T non_coding_transcript_exon_variant 0.71
rrs 1471914 n.69A>G non_coding_transcript_exon_variant 0.21
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.43
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.63
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.67
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.81
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.88
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.98
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.75
rrs 1472210 n.365A>T non_coding_transcript_exon_variant 0.56
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.48
rrs 1472222 n.377G>A non_coding_transcript_exon_variant 0.22
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.43
rrs 1472378 n.533G>T non_coding_transcript_exon_variant 0.72
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.72
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.68
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.42
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.55
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.79
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.54
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.43
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.41
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.24
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.87
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.77
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.61
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.22
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.71
rrs 1472953 n.1108G>A non_coding_transcript_exon_variant 0.28
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.11
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.19
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.23
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.19
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.3
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.26
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.26
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 0.15
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.66
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.79
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.83
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.55
rrl 1474275 n.618T>A non_coding_transcript_exon_variant 0.11
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.52
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.76
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.78
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.56
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.2
rrl 1475363 n.1706C>A non_coding_transcript_exon_variant 0.18
rrl 1475550 n.1893A>C non_coding_transcript_exon_variant 0.16
rrl 1475552 n.1895G>T non_coding_transcript_exon_variant 0.16
rrl 1475554 n.1897T>C non_coding_transcript_exon_variant 0.15
rrl 1475574 n.1917C>G non_coding_transcript_exon_variant 0.27
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.38
rrl 1475707 n.2050T>A non_coding_transcript_exon_variant 0.4
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.41
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.41
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.47
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.48
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.5
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.72
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.73
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.75
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.67
rrl 1476135 n.2478T>C non_coding_transcript_exon_variant 0.16
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.42
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.59
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.62
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.45
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 0.54
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.84
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.87
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.68
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.26
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.71
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.98
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.98
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.98
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.96
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.89
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.54
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 0.26
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.17
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.37
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.49
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.46
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.44
rrl 1476595 n.2938C>A non_coding_transcript_exon_variant 0.22
fabG1 1673299 c.-141T>C upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.26
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568631 p.Val17Phe missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
ethA 4328329 c.-856C>G upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0