TB-Profiler result

Run: ERR4817826
Summary

Run ID: ERR4817826

Sample name:

Date: 01-04-2023 15:12:56

Number of reads: 899797

Percentage reads mapped: 64.86

Strain: lineage4.5

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.17 rifampicin
rrs 1472362 n.517C>T non_coding_transcript_exon_variant 0.83 streptomycin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.18 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.43 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.42 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.4 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6207 p.Ala323Val missense_variant 0.14
gyrB 6255 p.Lys339Thr missense_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9680 c.2379G>A synonymous_variant 0.2
gyrA 9788 p.Asp829Glu missense_variant 1.0
mshA 575398 c.51T>C synonymous_variant 0.12
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoB 761102 c.1296A>G synonymous_variant 0.16
rpoB 761123 c.1317G>C synonymous_variant 0.12
rpoB 761126 c.1320G>C synonymous_variant 0.17
rpoB 761132 c.1326G>C synonymous_variant 0.15
rpoB 761133 c.1327T>C synonymous_variant 0.15
rpoB 761150 c.1344A>T synonymous_variant 0.16
rpoB 761159 c.1353G>C synonymous_variant 0.11
rpoB 761165 c.1359G>C synonymous_variant 0.1
rpoB 761442 p.Gly546Cys missense_variant 0.13
rpoB 762024 p.Val740Ile missense_variant 0.15
rpoB 762051 p.His749Tyr missense_variant 0.18
rpoB 762057 p.Ile751Val missense_variant 0.13
rpoB 762062 c.2256T>C synonymous_variant 0.13
rpoB 762065 c.2259T>C synonymous_variant 0.12
rpoB 762080 c.2274G>C synonymous_variant 0.13
rpoB 762085 p.Ala760Glu missense_variant 0.18
rpoB 762089 c.2283G>A synonymous_variant 0.17
rpoB 762185 c.2379G>C synonymous_variant 0.15
rpoB 762194 c.2388G>C synonymous_variant 0.23
rpoB 762200 c.2394C>T synonymous_variant 0.23
rpoB 762206 c.2400C>T synonymous_variant 0.15
rpoB 762212 c.2406G>C synonymous_variant 0.13
rpoB 762233 c.2427G>C synonymous_variant 0.16
rpoB 762236 c.2430G>C synonymous_variant 0.15
rpoB 762245 c.2439G>C synonymous_variant 0.12
rpoB 762254 c.2448T>C synonymous_variant 0.15
rpoB 762879 p.Met1025Leu missense_variant 0.19
rpoC 762902 c.-468C>T upstream_gene_variant 0.17
rpoC 762911 c.-459C>T upstream_gene_variant 0.18
rpoC 762917 c.-453C>T upstream_gene_variant 0.19
rpoC 762920 c.-450C>T upstream_gene_variant 0.19
rpoC 762929 c.-441G>T upstream_gene_variant 0.19
rpoC 762944 c.-426C>T upstream_gene_variant 0.19
rpoC 762956 c.-414G>C upstream_gene_variant 0.16
rpoC 762962 c.-408C>T upstream_gene_variant 0.17
rpoC 762989 c.-381G>C upstream_gene_variant 0.12
rpoC 763043 c.-327G>C upstream_gene_variant 0.11
rpoC 763053 c.-317T>C upstream_gene_variant 0.11
rpoC 763070 c.-300T>C upstream_gene_variant 0.12
rpoB 763077 p.Val1091Ser missense_variant 0.12
rpoC 763115 c.-255T>C upstream_gene_variant 0.2
rpoB 763119 p.Asn1105Asp missense_variant 0.13
rpoC 763127 c.-243G>C upstream_gene_variant 0.14
rpoC 764602 c.1233C>T synonymous_variant 0.17
rpoC 764605 c.1236G>T synonymous_variant 0.16
rpoC 764611 c.1242G>T synonymous_variant 0.16
rpoC 764632 c.1263T>C synonymous_variant 0.16
rpoC 764647 c.1278C>T synonymous_variant 0.19
rpoC 764650 c.1281G>T synonymous_variant 0.18
rpoC 764653 c.1284G>C synonymous_variant 0.18
rpoC 764656 c.1287C>T synonymous_variant 0.18
rpoC 764659 c.1290C>T synonymous_variant 0.12
rpoC 764662 c.1293G>C synonymous_variant 0.19
rpoC 764668 c.1299C>T synonymous_variant 0.14
rpoC 764677 c.1308C>A synonymous_variant 0.13
rpoC 764678 p.Lys437Gln missense_variant 0.2
rpoC 764681 p.Leu438Met missense_variant 0.24
rpoC 764692 c.1323C>T synonymous_variant 0.5
rpoC 764706 p.Leu446Gln missense_variant 0.44
rpoC 764731 c.1362G>C synonymous_variant 0.34
rpoC 764737 c.1368G>T synonymous_variant 0.34
rpoC 764746 c.1377G>T synonymous_variant 0.33
rpoC 764755 p.Asp462Glu missense_variant 0.34
rpoC 764758 c.1389C>G synonymous_variant 0.29
rpoC 764760 p.Asn464Ser missense_variant 0.29
rpoC 764764 c.1395T>C synonymous_variant 0.3
rpoC 764767 c.1398G>T synonymous_variant 0.29
rpoC 764776 c.1407C>T synonymous_variant 0.3
rpoC 764861 p.Leu498Val missense_variant 0.12
rpoC 765044 p.Met559Val missense_variant 0.1
rpoC 765297 p.Pro643Leu missense_variant 0.29
rpoC 766521 p.Gly1051Val missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776393 c.2088C>T synonymous_variant 0.15
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781751 c.192G>C synonymous_variant 0.15
rpsL 781754 c.195G>A synonymous_variant 0.15
rpsL 781766 c.207C>T synonymous_variant 0.27
rpsL 781772 c.213C>T synonymous_variant 0.23
rpsL 781796 p.Met79Ile missense_variant 0.39
rpsL 781802 c.243G>C synonymous_variant 0.38
rpsL 781805 c.246G>T synonymous_variant 0.26
rpsL 781811 c.252C>T synonymous_variant 0.35
rpsL 781814 c.255C>T synonymous_variant 0.35
rpsL 781817 c.258G>T synonymous_variant 0.35
rpsL 781829 c.270G>C synonymous_variant 0.29
rpsL 781832 c.273T>C synonymous_variant 0.33
rpsL 781838 c.279G>T synonymous_variant 0.25
fbiC 1303818 c.888C>T synonymous_variant 0.12
Rv1258c 1406852 c.488delT frameshift_variant 0.15
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 0.33
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.25
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.44
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.52
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.54
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.81
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.52
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.49
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.19
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.17
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.16
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.98
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.23
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.22
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.76
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.22
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.25
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.3
rrs 1472274 n.429A>G non_coding_transcript_exon_variant 0.12
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 1.0
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.62
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.62
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.67
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.26
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.38
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.38
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.54
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.6
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.65
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.65
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.23
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.59
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.22
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.64
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.6
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.15
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.97
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.16
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.66
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.66
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.17
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.33
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.29
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.79
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.79
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.5
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.32
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.44
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.5
rrs 1472673 n.828T>A non_coding_transcript_exon_variant 0.5
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.67
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.6
rrs 1472681 n.837_838delTT non_coding_transcript_exon_variant 0.67
rrs 1472687 n.843dupT non_coding_transcript_exon_variant 0.57
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.46
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.23
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.39
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.35
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.6
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.36
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.41
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.43
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.42
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.42
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.55
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.42
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.45
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.91
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.37
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.25
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.91
rrs 1472875 n.1030T>C non_coding_transcript_exon_variant 0.4
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.95
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.82
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.14
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.81
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.95
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.96
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.98
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.82
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.83
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.95
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.95
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.93
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.93
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.93
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.14
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.14
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.93
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.9
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.89
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.78
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.88
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.89
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.89
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.66
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.88
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.21
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.27
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.95
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.94
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.33
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.34
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.38
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.87
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.87
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.19
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.6
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.78
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.25
rrs 1473293 n.1449delA non_coding_transcript_exon_variant 0.11
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.17
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.74
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.61
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.77
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.6
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.89
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.8
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.2
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.92
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.83
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.83
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.12
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.93
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.2
rrl 1474275 n.618T>C non_coding_transcript_exon_variant 1.0
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 1.0
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0
rrl 1474383 n.726G>T non_coding_transcript_exon_variant 0.67
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0
rrl 1474406 n.749T>A non_coding_transcript_exon_variant 0.67
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 1.0
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 1.0
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 1.0
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 1.0
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.67
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 0.67
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.8
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.33
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.33
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.33
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.33
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.67
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.67
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.67
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.6
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.8
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 0.8
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.8
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 1.0
rrl 1475715 n.2058G>C non_coding_transcript_exon_variant 0.4
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.4
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.4
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.29
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.29
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.29
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.67
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.71
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.36
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.25
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.75
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.75
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.75
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.75
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.33
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.75
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.5
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.5
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.18
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.4
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.57
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.57
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.43
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.57
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.15
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.46
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.54
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.43
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.62
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.62
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.67
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.75
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.67
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.53
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.91
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.96
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.94
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.89
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.82
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.82
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.76
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.76
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.17
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.64
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.7
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.7
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.67
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.67
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.67
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.67
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.67
inhA 1674862 p.Gly221Ser missense_variant 0.22
rpsA 1833700 c.159C>T synonymous_variant 0.15
rpsA 1833721 c.180A>G synonymous_variant 0.12
rpsA 1833727 c.186G>C synonymous_variant 0.17
rpsA 1833732 p.Pro64Leu missense_variant 0.16
rpsA 1833736 c.195C>T synonymous_variant 0.14
rpsA 1833742 c.201A>G synonymous_variant 0.14
rpsA 1834210 c.669C>T synonymous_variant 0.15
rpsA 1834213 c.672G>A synonymous_variant 0.15
rpsA 1834219 c.678C>G synonymous_variant 0.14
rpsA 1834222 c.681T>C synonymous_variant 0.14
rpsA 1834225 c.684C>G synonymous_variant 0.15
rpsA 1834228 c.687C>T synonymous_variant 0.15
rpsA 1834231 c.690T>C synonymous_variant 0.15
rpsA 1834246 c.705G>T synonymous_variant 0.12
rpsA 1834249 c.708T>C synonymous_variant 0.21
rpsA 1834252 c.711C>T synonymous_variant 0.11
rpsA 1834261 c.720A>G synonymous_variant 0.21
rpsA 1834264 c.723G>C synonymous_variant 0.21
rpsA 1834294 c.753G>C synonymous_variant 0.11
rpsA 1834298 p.Gln253Glu missense_variant 0.16
rpsA 1834607 p.Arg356Cys missense_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2168145 p.Pro823Gln missense_variant 0.12
PPE35 2170394 c.219G>A synonymous_variant 1.0
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2221722 c.1443C>T synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289500 c.-260delG upstream_gene_variant 0.17
folC 2746586 p.Arg338Leu missense_variant 0.14
folC 2747370 p.Ser77Pro missense_variant 0.11
Rv3083 3448569 c.66C>T synonymous_variant 0.14
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612577 c.540G>A synonymous_variant 0.12
Rv3236c 3612965 c.151delG frameshift_variant 0.11
rpoA 3878438 p.Glu24Lys missense_variant 0.12
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
clpC1 4038318 p.Pro796Leu missense_variant 1.0
clpC1 4039607 p.Tyr366* stop_gained 0.2
clpC1 4040632 p.His25Tyr missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244703 p.Pro491Ser missense_variant 0.11
aftB 4267192 p.Gly549Ser missense_variant 0.13
ethR 4327249 c.-300G>A upstream_gene_variant 0.12
gid 4408372 c.-170G>A upstream_gene_variant 0.14