TB-Profiler result

Run: SRR13861556
Summary

Run ID: SRR13861556

Sample name:

Date: 03-04-2023 09:34:46

Number of reads: 545768

Percentage reads mapped: 13.66

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.27 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.89 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6169 c.930C>G synonymous_variant 0.17
gyrB 6190 c.951A>G synonymous_variant 0.2
gyrB 6209 c.970C>T synonymous_variant 0.18
gyrB 6214 c.975G>C synonymous_variant 0.18
gyrB 6217 c.978G>C synonymous_variant 0.18
gyrB 6223 c.984G>C synonymous_variant 0.17
gyrB 6242 p.Arg335Lys missense_variant 0.17
gyrB 6250 c.1011A>G synonymous_variant 0.17
gyrB 6253 c.1014G>C synonymous_variant 0.17
gyrB 6280 c.1041T>C synonymous_variant 0.17
gyrA 7694 c.393A>G synonymous_variant 0.15
gyrA 7697 c.396C>G synonymous_variant 0.14
gyrA 7710 c.409T>C synonymous_variant 0.15
gyrA 7715 c.414G>C synonymous_variant 0.14
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.14
gyrA 7760 c.459C>T synonymous_variant 0.14
gyrA 7763 c.462T>C synonymous_variant 0.19
gyrA 7837 p.Gly179Val missense_variant 0.96
gyrA 8069 c.768T>C synonymous_variant 0.13
gyrA 8078 c.777A>G synonymous_variant 0.12
gyrA 8090 c.789C>G synonymous_variant 0.18
gyrA 8096 c.795T>C synonymous_variant 0.17
gyrA 8099 c.798T>C synonymous_variant 0.21
gyrA 8111 c.810G>C synonymous_variant 0.21
gyrA 8168 c.867A>G synonymous_variant 0.15
gyrA 8174 c.873C>G synonymous_variant 0.14
gyrA 8177 c.876A>C synonymous_variant 0.14
gyrA 8198 c.897T>C synonymous_variant 0.14
gyrA 8204 c.903C>T synonymous_variant 0.19
gyrA 8207 c.906T>C synonymous_variant 0.15
gyrA 8216 c.915G>A synonymous_variant 0.16
gyrA 8219 c.918T>C synonymous_variant 0.21
gyrA 8225 c.924T>C synonymous_variant 0.17
gyrA 8234 c.933T>G synonymous_variant 0.12
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.12
gyrA 8253 p.Ile318Leu missense_variant 0.18
gyrA 8264 c.963T>C synonymous_variant 0.18
gyrA 8267 c.966G>C synonymous_variant 0.13
gyrA 8270 c.969G>C synonymous_variant 0.18
gyrA 8283 p.Ile328Leu missense_variant 0.17
gyrA 8288 c.987T>C synonymous_variant 0.17
gyrA 8294 c.993T>C synonymous_variant 0.15
gyrA 8324 c.1023T>C synonymous_variant 0.18
gyrA 8339 c.1038A>G synonymous_variant 0.17
gyrA 8756 c.1455A>G synonymous_variant 0.16
gyrA 8762 c.1461G>C synonymous_variant 0.17
gyrA 8765 p.Asp488Glu missense_variant 0.17
gyrA 8767 p.Arg489Lys missense_variant 0.17
gyrA 8852 c.1551T>C synonymous_variant 0.18
gyrA 8858 c.1557T>C synonymous_variant 0.17
gyrA 8867 c.1566A>G synonymous_variant 0.17
gyrA 8870 c.1569G>C synonymous_variant 0.17
gyrA 8873 c.1572A>C synonymous_variant 0.17
gyrA 9182 c.1881T>C synonymous_variant 0.14
gyrA 9191 c.1890G>C synonymous_variant 0.13
gyrA 9200 c.1899A>G synonymous_variant 0.15
gyrA 9204 p.Ser635Thr missense_variant 0.17
gyrA 9227 c.1926C>G synonymous_variant 0.22
gyrA 9230 c.1929T>C synonymous_variant 0.22
gyrA 9242 c.1941A>C synonymous_variant 0.22
gyrA 9252 p.Val651Ile missense_variant 0.2
gyrA 9275 c.1974G>A synonymous_variant 0.18
gyrA 9278 c.1977G>C synonymous_variant 0.18
gyrA 9281 c.1980C>G synonymous_variant 0.17
gyrA 9284 c.1983T>C synonymous_variant 0.15
gyrA 9291 c.1990C>T synonymous_variant 0.15
gyrA 9304 p.Gly668Glu missense_variant 0.14
gyrA 9311 c.2010C>T synonymous_variant 0.14
gyrA 9335 c.2034G>C synonymous_variant 0.13
gyrA 9345 c.2044A>C synonymous_variant 0.14
rpoB 760070 c.264T>G synonymous_variant 0.15
rpoB 760088 c.282C>G synonymous_variant 0.12
rpoB 760181 c.375T>C synonymous_variant 0.18
rpoB 760184 c.378A>G synonymous_variant 0.17
rpoB 760196 c.390C>G synonymous_variant 0.14
rpoB 761327 c.1521A>G synonymous_variant 0.15
rpoB 761362 p.Ser519Thr missense_variant 0.12
rpoB 761414 c.1608A>G synonymous_variant 0.15
rpoB 761423 c.1617T>C synonymous_variant 0.15
rpoB 761864 c.2058G>C synonymous_variant 0.13
rpoB 762008 c.2202C>G synonymous_variant 0.12
rpoB 762257 c.2451C>G synonymous_variant 0.96
rpoC 764644 c.1275G>C synonymous_variant 0.19
rpoC 764650 c.1281G>T synonymous_variant 0.19
rpoC 765970 c.2601C>T synonymous_variant 0.12
rpoC 765979 c.2610C>G synonymous_variant 0.13
rpoC 765985 c.2616C>T synonymous_variant 0.13
rpoC 765994 c.2625A>T synonymous_variant 0.19
rpoC 766009 c.2640G>C synonymous_variant 0.18
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.17
rpoC 766021 c.2652G>C synonymous_variant 0.19
rpoC 766043 p.Gln892Glu missense_variant 0.15
rpoC 766054 c.2685C>G synonymous_variant 0.15
rpoC 766069 c.2700G>A synonymous_variant 0.14
rpoC 766082 p.Ala905Gln missense_variant 0.18
rpoC 766096 c.2727G>C synonymous_variant 0.14
rpoC 766105 c.2736C>T synonymous_variant 0.14
rpoC 766129 c.2760C>G synonymous_variant 0.13
mmpL5 777730 p.Gly251Arg missense_variant 1.0
rpsL 781682 c.123T>C synonymous_variant 0.12
rpsL 781715 c.156T>C synonymous_variant 0.16
rpsL 781728 c.169T>C synonymous_variant 0.15
rpsL 781736 c.177T>C synonymous_variant 0.14
rplC 801156 c.348T>A synonymous_variant 0.12
rplC 801222 c.414T>C synonymous_variant 0.14
rplC 801228 c.420T>C synonymous_variant 0.14
rplC 801249 c.441T>G synonymous_variant 0.16
rplC 801255 c.447C>T synonymous_variant 0.16
rplC 801267 c.459A>C synonymous_variant 0.17
rplC 801270 c.462T>C synonymous_variant 0.17
rplC 801276 c.468G>C synonymous_variant 0.21
rplC 801279 c.471G>C synonymous_variant 0.16
rplC 801282 c.474G>C synonymous_variant 0.17
rplC 801324 c.516T>C synonymous_variant 0.12
fbiC 1304628 c.1698G>C synonymous_variant 0.18
fbiC 1304634 c.1704C>G synonymous_variant 0.16
fbiC 1304640 c.1710A>C synonymous_variant 0.15
fbiC 1304646 c.1716T>C synonymous_variant 0.16
fbiC 1304658 c.1728C>G synonymous_variant 0.14
fbiC 1304671 p.Val581Thr missense_variant 0.15
fbiC 1304675 p.Gly582Glu missense_variant 0.14
fbiC 1304691 c.1761G>C synonymous_variant 0.14
fbiC 1304703 c.1773C>G synonymous_variant 0.14
fbiC 1304715 c.1785G>C synonymous_variant 0.18
fbiC 1304724 c.1794A>G synonymous_variant 0.15
fbiC 1304727 c.1797A>G synonymous_variant 0.15
fbiC 1304742 c.1812T>C synonymous_variant 0.16
fbiC 1304748 c.1818T>C synonymous_variant 0.17
fbiC 1304816 p.His629Arg missense_variant 0.95
fbiC 1304869 p.Leu647Met missense_variant 1.0
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.21
rrs 1472101 n.256G>A non_coding_transcript_exon_variant 0.44
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.44
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.64
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.72
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.66
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.76
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.76
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.77
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.77
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.77
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.79
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.81
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.81
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.8
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.8
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.8
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.81
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.77
rrs 1472230 n.385C>T non_coding_transcript_exon_variant 0.2
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.76
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.77
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.74
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.66
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.57
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.5
rrs 1472262 n.417C>T non_coding_transcript_exon_variant 0.46
rrs 1472269 n.424G>A non_coding_transcript_exon_variant 0.27
rrs 1472271 n.426T>C non_coding_transcript_exon_variant 0.27
rrs 1472277 n.432C>A non_coding_transcript_exon_variant 0.14
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.27
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.45
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.75
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.76
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.78
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.79
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.79
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.79
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.77
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.8
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.8
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.8
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.78
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.82
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.81
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.81
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.86
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.88
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.89
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.88
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.86
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.87
rrs 1472669 n.824_825insTAGG non_coding_transcript_exon_variant 0.88
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.87
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.88
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.89
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.88
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.88
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.88
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.72
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.14
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.13
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.13
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.19
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.14
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.52
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.52
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.52
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.52
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.5
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.5
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.54
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.56
rrs 1473281 n.1436C>A non_coding_transcript_exon_variant 0.56
rrs 1473282 n.1437C>G non_coding_transcript_exon_variant 0.56
rrs 1473288 n.1443C>A non_coding_transcript_exon_variant 0.6
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.55
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.52
rrs 1473296 n.1451G>C non_coding_transcript_exon_variant 0.52
rrs 1473297 n.1452G>T non_coding_transcript_exon_variant 0.52
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.5
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.54
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.54
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.5
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.24
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.2
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.16
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.12
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.19
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.17
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.18
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.18
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.17
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.17
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.29
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.84
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.88
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.89
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.89
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.87
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.88
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.88
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.88
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.88
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.89
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.9
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.9
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.9
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.9
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.9
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.9
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.9
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.91
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.94
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.95
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.96
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.96
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.96
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.95
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.77
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.95
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.95
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.96
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.96
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.95
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.95
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.91
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.86
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.83
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.85
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.85
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.84
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.84
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.83
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.83
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.83
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.83
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.84
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.81
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.81
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.82
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.81
rrl 1476595 n.2938C>G non_coding_transcript_exon_variant 0.27
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.17
inhA 1674561 c.360C>T synonymous_variant 0.13
inhA 1674582 c.381T>C synonymous_variant 0.12
rpsA 1833787 c.246C>G synonymous_variant 0.16
rpsA 1833790 c.249T>A synonymous_variant 0.16
rpsA 1833799 c.258C>G synonymous_variant 0.19
rpsA 1833838 c.297G>C synonymous_variant 0.12
rpsA 1833862 c.321G>T synonymous_variant 0.12
rpsA 1833874 c.333T>C synonymous_variant 0.15
rpsA 1833928 c.387G>C synonymous_variant 0.21
rpsA 1833940 c.399C>G synonymous_variant 0.17
rpsA 1833970 c.429G>C synonymous_variant 0.17
rpsA 1833979 c.438T>C synonymous_variant 0.18
rpsA 1834000 c.459G>C synonymous_variant 0.19
rpsA 1834015 c.474G>C synonymous_variant 0.18
rpsA 1834021 c.480C>T synonymous_variant 0.17
rpsA 1834780 c.1239A>G synonymous_variant 0.14
tlyA 1918527 c.588G>T synonymous_variant 1.0
ndh 2102259 p.Ser262Ala missense_variant 1.0
ndh 2102557 c.485delG frameshift_variant 1.0
katG 2155701 c.411C>T synonymous_variant 0.14
katG 2155704 c.408C>G synonymous_variant 0.13
katG 2156260 c.-149C>A upstream_gene_variant 1.0
PPE35 2169123 p.Thr497Ile missense_variant 1.0
folC 2747355 p.Val82Ile missense_variant 0.15
folC 2747359 c.240C>G synonymous_variant 0.14
folC 2747362 c.237G>C synonymous_variant 0.14
Rv2752c 3066145 p.Leu16Ser missense_variant 0.92
thyX 3067316 c.630A>G synonymous_variant 0.15
thyX 3067325 c.621A>G synonymous_variant 0.14
thyX 3067355 c.591A>C synonymous_variant 0.25
thyX 3067367 c.579G>C synonymous_variant 0.21
thyX 3067376 c.570G>C synonymous_variant 0.27
thyX 3067391 c.555G>C synonymous_variant 0.22
thyX 3067394 c.552G>C synonymous_variant 0.24
thyX 3067412 c.534C>G synonymous_variant 0.24
thyX 3067439 c.507A>G synonymous_variant 0.21
thyX 3067445 c.501C>G synonymous_variant 0.21
thyX 3067451 c.495G>A synonymous_variant 0.21
thyX 3067457 c.489C>G synonymous_variant 0.19
thyX 3067465 p.Ile161Val missense_variant 0.14
thyX 3067466 c.480G>C synonymous_variant 0.14
thyX 3067470 p.Asn159Ser missense_variant 0.15
Rv3236c 3612326 p.Thr264Ile missense_variant 1.0
Rv3236c 3612504 p.His205Tyr missense_variant 1.0
Rv3236c 3612779 p.Leu113* stop_gained 1.0
fbiB 3640821 c.-714G>C upstream_gene_variant 1.0
rpoA 3878169 c.339G>C synonymous_variant 0.13
rpoA 3878184 c.324C>T synonymous_variant 0.13
rpoA 3878187 c.321C>G synonymous_variant 0.13
rpoA 3878193 c.315T>C synonymous_variant 0.15
rpoA 3878199 c.309T>C synonymous_variant 0.15
rpoA 3878271 c.237T>C synonymous_variant 0.13
rpoA 3878284 p.Glu75Ala missense_variant 0.16
rpoA 3878381 p.Leu43Met missense_variant 0.88
rpoA 3878543 c.-36G>C upstream_gene_variant 1.0
clpC1 4038596 c.2109A>G synonymous_variant 0.15
clpC1 4038683 c.2022T>C synonymous_variant 0.14
clpC1 4038695 c.2010C>G synonymous_variant 0.14
clpC1 4038740 c.1965G>C synonymous_variant 0.16
clpC1 4038748 p.Arg653Cys missense_variant 0.15
clpC1 4038755 c.1950G>C synonymous_variant 0.14
clpC1 4038773 c.1932T>C synonymous_variant 0.14
clpC1 4038782 c.1923G>C synonymous_variant 0.14
clpC1 4038923 c.1782A>G synonymous_variant 0.18
clpC1 4038974 c.1731T>C synonymous_variant 0.14
clpC1 4038989 c.1716T>C synonymous_variant 0.18
clpC1 4039526 c.1179G>C synonymous_variant 0.18
clpC1 4039622 c.1083C>G synonymous_variant 0.15
clpC1 4039694 c.1011G>C synonymous_variant 0.13
clpC1 4039724 c.981A>G synonymous_variant 0.16
clpC1 4039748 c.957G>C synonymous_variant 0.16
clpC1 4039751 c.954A>G synonymous_variant 0.17
clpC1 4039757 c.948A>G synonymous_variant 0.17
clpC1 4039760 c.945T>C synonymous_variant 0.16
clpC1 4039766 c.939T>C synonymous_variant 0.17
clpC1 4040354 c.351A>G synonymous_variant 0.17
clpC1 4040363 c.342A>C synonymous_variant 0.15
clpC1 4040369 c.336C>G synonymous_variant 0.17
clpC1 4040380 c.325T>C synonymous_variant 0.17
clpC1 4040381 c.324T>C synonymous_variant 0.17
clpC1 4040387 c.318A>G synonymous_variant 0.15
clpC1 4040411 c.294T>C synonymous_variant 0.13
clpC1 4040423 c.282A>G synonymous_variant 0.13
clpC1 4040426 c.279T>C synonymous_variant 0.13
clpC1 4040431 c.274T>C synonymous_variant 0.13
clpC1 4040441 c.264C>G synonymous_variant 0.13
embC 4240536 c.678delC frameshift_variant 1.0
embB 4248007 c.1494C>G synonymous_variant 0.15
embB 4248011 p.Ser500Ala missense_variant 0.17
embB 4248035 p.Val508Ile missense_variant 0.2
embB 4248041 p.Ala510Thr missense_variant 0.2
embB 4248044 p.Lys511Ala missense_variant 0.2
embB 4248052 c.1539G>A synonymous_variant 0.21
embB 4248055 c.1542G>C synonymous_variant 0.21
embB 4248064 c.1551G>C synonymous_variant 0.24
embB 4248070 c.1557T>C synonymous_variant 0.27
embB 4248085 c.1572T>C synonymous_variant 0.32
embB 4248097 c.1584C>G synonymous_variant 0.35
embB 4248118 c.1605T>C synonymous_variant 0.3
embB 4248127 c.1614G>C synonymous_variant 0.32
embB 4248133 c.1620C>G synonymous_variant 0.35
embB 4248142 c.1629T>C synonymous_variant 0.32
embB 4248143 c.1630T>C synonymous_variant 0.32
embB 4248157 c.1644A>G synonymous_variant 0.33
embB 4248206 p.Ser565Gly missense_variant 0.4
embB 4248220 c.1707A>G synonymous_variant 0.25
embB 4248241 c.1728C>T synonymous_variant 0.27
embB 4248265 c.1752C>T synonymous_variant 0.18
embB 4248266 c.1753C>T synonymous_variant 0.18
embB 4248277 c.1764G>C synonymous_variant 0.19
embB 4248562 c.2049G>C synonymous_variant 1.0