TB-Profiler result

Run: SRR5818404
Summary

Run ID: SRR5818404

Sample name:

Date: 04-04-2023 11:24:14

Number of reads: 807737

Percentage reads mapped: 99.7

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.26 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rrs 1472119 n.274G>A non_coding_transcript_exon_variant 0.24
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.91
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.9
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.85
rrs 1472282 n.437T>G non_coding_transcript_exon_variant 0.14
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.12
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.2
rrs 1472332 n.487A>G non_coding_transcript_exon_variant 0.19
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.19
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.25
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.33
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.54
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.56
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.31
rrs 1472416 n.571C>T non_coding_transcript_exon_variant 0.53
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.52
rrs 1472427 n.582T>G non_coding_transcript_exon_variant 0.32
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.43
rrs 1472436 n.591G>T non_coding_transcript_exon_variant 0.43
rrs 1472437 n.592T>G non_coding_transcript_exon_variant 0.44
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.45
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.45
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.45
rrs 1472450 n.605A>C non_coding_transcript_exon_variant 0.45
rrs 1472451 n.606C>T non_coding_transcript_exon_variant 0.46
rrs 1472462 n.617T>G non_coding_transcript_exon_variant 0.47
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.48
rrs 1472473 n.628G>T non_coding_transcript_exon_variant 0.47
rrs 1472474 n.629C>G non_coding_transcript_exon_variant 0.47
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.48
rrs 1472484 n.639A>T non_coding_transcript_exon_variant 0.33
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.32
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.66
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.52
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.52
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.71
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.34
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.36
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.75
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.68
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.51
rrs 1472597 n.752G>A non_coding_transcript_exon_variant 0.36
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.36
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.44
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.71
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.67
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.33
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.56
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.34
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.59
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.12
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.14
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.14
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.14
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.17
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.16
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.14
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.14
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.12
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.16
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 1.0
rrl 1474199 n.542G>A non_coding_transcript_exon_variant 1.0
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 1.0
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.15
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.15
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.15
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.3
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.2
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.3
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.21
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.18
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.25
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.3
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.15
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.36
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.22
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.31
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.29
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.29
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.19
tlyA 1917972 c.33A>G synonymous_variant 1.0
ahpC 2726184 c.-9A>C upstream_gene_variant 0.5