TB-Profiler result

Run: SRR6981999
Summary

Run ID: SRR6981999

Sample name:

Date: 04-04-2023 18:24:30

Number of reads: 1681034

Percentage reads mapped: 91.21

Strain: lineage2.2.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.98
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.99
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.97
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 0.97
mshA 575907 p.Ala187Val missense_variant 0.98
ccsA 620625 p.Ile245Met missense_variant 0.97
rpoC 763031 c.-339T>C upstream_gene_variant 0.94
rpoC 764692 c.1323C>T synonymous_variant 0.12
rpoC 764701 c.1332C>G synonymous_variant 0.12
rpoC 764713 c.1344G>T synonymous_variant 0.12
rpoC 764719 c.1350G>A synonymous_variant 0.12
rpoC 766500 p.Ala1044Val missense_variant 0.94
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.98
mmpL5 776182 p.Asp767Asn missense_variant 0.96
mmpS5 779615 c.-710C>G upstream_gene_variant 0.99
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406760 c.580_581insC frameshift_variant 0.99
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.12
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.12
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 0.12
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.12
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.12
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.12
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.12
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 0.12
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.12
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.12
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.13
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.13
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 0.11
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.12
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.12
rrl 1475062 n.1405A>T non_coding_transcript_exon_variant 0.12
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.14
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.14
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.14
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.17
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.2
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.21
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 0.21
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.21
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.21
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 0.21
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.21
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.21
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.12
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 0.12
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.12
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.13
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.15
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.16
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.15
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.16
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.15
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.14
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.13
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.12
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.13
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.15
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.13
rpsA 1833749 p.Ile70Leu missense_variant 0.91
rpsA 1834015 c.474G>C synonymous_variant 0.11
rpsA 1834021 c.480C>T synonymous_variant 0.11
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834361 c.820T>C synonymous_variant 0.12
rpsA 1834366 c.825A>G synonymous_variant 0.12
rpsA 1834396 c.855G>C synonymous_variant 0.13
rpsA 1834411 c.870T>C synonymous_variant 0.12
rpsA 1834423 c.882G>T synonymous_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.97
PPE35 2167926 p.Leu896Ser missense_variant 0.96
Rv1979c 2222645 p.Leu174Phe missense_variant 0.92
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714526 c.805_806delAC frameshift_variant 0.94
ribD 2987583 p.Gly249Ser missense_variant 0.94
Rv2752c 3065711 p.Gly161Ser missense_variant 0.96
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 0.98
embB 4249547 p.Phe1012Leu missense_variant 0.93
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.99
gid 4407927 p.Glu92Asp missense_variant 0.99