TB-Profiler result

Run: ERR2229336
Summary

Run ID: ERR2229336

Sample name:

Date: 31-03-2023 17:01:58

Number of reads: 613223

Percentage reads mapped: 37.21

Strain: lineage4.8

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.94 streptomycin
panD 4043931 p.Met117Ile missense_variant 0.15 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5903 p.Val222Leu missense_variant 0.14
gyrA 6478 c.-824G>A upstream_gene_variant 0.17
gyrB 7256 p.Leu673Met missense_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7500 p.Asp67Tyr missense_variant 0.12
gyrA 7640 c.339G>A synonymous_variant 0.13
gyrA 8326 p.Gly342Val missense_variant 0.12
gyrA 8352 p.Gly351Trp missense_variant 0.15
gyrA 8777 c.1476C>T synonymous_variant 0.12
gyrA 9000 p.Ile567Val missense_variant 0.1
gyrA 9719 c.2418G>C synonymous_variant 0.2
fgd1 491683 p.Val301Leu missense_variant 0.18
mshA 575734 c.387T>C synonymous_variant 0.11
mshA 575971 p.Asp208Glu missense_variant 0.15
ccsA 620122 c.232C>A synonymous_variant 0.14
rpoB 759979 p.Leu58Pro missense_variant 0.11
rpoB 760444 p.Arg213Leu missense_variant 0.17
rpoB 761536 p.Pro577His missense_variant 0.17
rpoB 762146 p.Glu780Asp missense_variant 0.13
rpoC 763852 c.483C>G synonymous_variant 0.17
rpoC 764227 c.858G>T synonymous_variant 0.12
rpoC 764869 c.1500C>A synonymous_variant 0.15
rpoC 765219 p.Glu617Gly missense_variant 0.14
rpoC 765477 p.Arg703Leu missense_variant 0.12
rpoC 766229 p.Ala954Thr missense_variant 0.2
rpoC 766388 p.Gly1007Cys missense_variant 0.13
rpoC 766631 p.Val1088Met missense_variant 0.33
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776470 p.Glu671* stop_gained 0.14
mmpL5 777810 p.Arg224Gln missense_variant 0.12
mmpR5 778313 c.-677G>T upstream_gene_variant 0.2
mmpL5 778348 p.Val45Ile missense_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781523 c.-37A>G upstream_gene_variant 0.11
rpsL 781681 p.Thr41Asn missense_variant 0.2
rplC 800635 c.-174G>T upstream_gene_variant 0.13
rplC 801128 p.Ala107Asp missense_variant 0.22
fbiC 1302763 c.-168G>T upstream_gene_variant 0.18
fbiC 1303305 c.375C>A synonymous_variant 0.22
fbiC 1303516 p.Met196Val missense_variant 0.25
fbiC 1303646 p.Ala239Glu missense_variant 0.18
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1304132 p.Ala401Gly missense_variant 0.22
fbiC 1304894 p.Gly655Asp missense_variant 0.14
fbiC 1304916 c.1986T>C synonymous_variant 0.18
Rv1258c 1407103 p.Ala80Ser missense_variant 0.5
Rv1258c 1407200 c.141G>T synonymous_variant 0.2
Rv1258c 1407423 c.-83G>A upstream_gene_variant 0.18
embR 1416769 c.579G>A synonymous_variant 0.25
embR 1417215 p.Asn45Asp missense_variant 0.11
embR 1417446 c.-99G>C upstream_gene_variant 0.33
atpE 1461072 p.Leu10Ile missense_variant 0.15
atpE 1461219 c.175T>C synonymous_variant 0.13
atpE 1461264 p.Phe74Leu missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471878 n.33C>T non_coding_transcript_exon_variant 0.29
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.29
rrs 1471900 n.55C>T non_coding_transcript_exon_variant 0.29
rrs 1472101 n.256G>A non_coding_transcript_exon_variant 0.5
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.5
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.94
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 1.0
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 1.0
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.92
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.95
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.95
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.95
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.96
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.96
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.93
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.93
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.91
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.92
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.92
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.84
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.81
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.8
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.79
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.56
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.5
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.38
rrs 1472262 n.417C>T non_coding_transcript_exon_variant 0.31
rrs 1472269 n.424G>A non_coding_transcript_exon_variant 0.27
rrs 1472271 n.426T>C non_coding_transcript_exon_variant 0.27
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.46
rrs 1472378 n.533G>T non_coding_transcript_exon_variant 0.5
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.5
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.5
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.5
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.33
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.36
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.69
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.69
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.72
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.72
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.72
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.72
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.71
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.65
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.65
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.71
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.71
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.73
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.73
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.75
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.76
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.76
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.5
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.33
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.33
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.33
rrs 1472669 n.824_825insTAGG non_coding_transcript_exon_variant 0.45
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.56
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.56
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.75
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.88
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.93
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.93
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.93
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.92
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.87
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.83
rrs 1472880 n.1035_1036insA non_coding_transcript_exon_variant 0.17
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.71
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.38
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.25
rrs 1473008 n.1164delT non_coding_transcript_exon_variant 0.25
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.42
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.57
rrs 1473191 n.1346C>T non_coding_transcript_exon_variant 0.77
rrs 1473206 n.1361G>A non_coding_transcript_exon_variant 0.89
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.84
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.8
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.8
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.8
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.8
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.73
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.73
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.63
rrs 1473281 n.1436C>A non_coding_transcript_exon_variant 0.56
rrs 1473282 n.1437C>G non_coding_transcript_exon_variant 0.56
rrs 1473288 n.1443C>A non_coding_transcript_exon_variant 0.53
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.59
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.59
rrs 1473296 n.1451G>C non_coding_transcript_exon_variant 0.56
rrs 1473297 n.1452G>T non_coding_transcript_exon_variant 0.56
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.56
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.61
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.61
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.78
rrl 1473479 n.-178delC upstream_gene_variant 0.22
rrl 1473697 n.40C>A non_coding_transcript_exon_variant 0.25
rrl 1473800 n.143G>T non_coding_transcript_exon_variant 0.25
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474283 n.626A>T non_coding_transcript_exon_variant 0.13
rrl 1474694 n.1037C>A non_coding_transcript_exon_variant 0.25
rrl 1474839 n.1182C>T non_coding_transcript_exon_variant 0.47
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.53
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.5
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.5
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.56
rrl 1474892 n.1235G>A non_coding_transcript_exon_variant 0.25
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.17
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.17
rrl 1474903 n.1246T>A non_coding_transcript_exon_variant 0.17
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.17
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 0.15
rrl 1474920 n.1263G>C non_coding_transcript_exon_variant 0.16
rrl 1475552 n.1895G>C non_coding_transcript_exon_variant 0.67
rrl 1475574 n.1917C>A non_coding_transcript_exon_variant 0.4
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.44
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.44
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.59
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.59
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.59
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.59
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.35
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.35
rrl 1475874 n.2217C>T non_coding_transcript_exon_variant 0.12
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.4
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.29
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.4
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.4
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.5
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.17
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.8
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.75
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.3
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.85
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.85
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.85
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.83
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.83
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.83
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.78
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.67
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.82
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.82
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.78
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.78
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.78
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.81
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.81
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.81
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.92
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.97
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.99
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.97
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.96
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.96
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.96
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.95
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.94
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.94
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.94
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.88
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.89
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.77
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.64
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.59
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.59
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.59
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.59
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.63
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.65
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.65
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.65
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.72
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.76
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.76
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.74
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.71
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.56
rrl 1476708 n.3051C>G non_coding_transcript_exon_variant 0.4
fabG1 1673380 c.-60C>G upstream_gene_variant 0.15
fabG1 1673786 p.Ala116Glu missense_variant 0.12
inhA 1674586 p.Ser129Pro missense_variant 0.17
inhA 1674838 p.Ala213Thr missense_variant 0.15
rpsA 1834910 c.1373delA frameshift_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918088 p.Thr50Asn missense_variant 0.23
ndh 2102211 p.Ala278Thr missense_variant 0.15
ndh 2102617 p.Asp142Glu missense_variant 0.33
ndh 2103024 p.Pro7Thr missense_variant 0.22
katG 2154867 c.1245G>T synonymous_variant 0.13
katG 2156091 c.21C>A synonymous_variant 0.15
katG 2156109 c.3G>A synonymous_variant 0.15
PPE35 2168696 c.1917C>A synonymous_variant 0.22
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2170620 c.-8G>C upstream_gene_variant 0.17
PPE35 2170775 c.-163T>C upstream_gene_variant 0.17
PPE35 2170786 c.-174G>T upstream_gene_variant 0.14
Rv1979c 2222750 p.Leu139Met missense_variant 0.15
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289910 c.-669C>A upstream_gene_variant 0.17
pncA 2290014 c.-773T>C upstream_gene_variant 0.17
kasA 2517948 c.-167C>A upstream_gene_variant 0.12
kasA 2519167 c.1053T>C synonymous_variant 0.12
kasA 2519171 p.Leu353Val missense_variant 0.12
kasA 2519280 p.Pro389Leu missense_variant 0.15
eis 2714885 p.His150Asn missense_variant 0.18
eis 2715280 p.Leu18Pro missense_variant 0.14
ahpC 2726630 p.Phe146Leu missense_variant 0.29
folC 2746435 c.1164C>T synonymous_variant 0.13
folC 2747273 p.Ser109* stop_gained 0.14
pepQ 2859678 c.741A>C synonymous_variant 0.15
pepQ 2859936 c.483C>A synonymous_variant 0.12
pepQ 2860600 c.-182A>C upstream_gene_variant 0.18
ribD 2986757 c.-82C>A upstream_gene_variant 0.17
ribD 2987037 p.Asp67Tyr missense_variant 0.25
Rv2752c 3067144 c.-953G>A upstream_gene_variant 0.33
thyX 3068046 c.-101G>T upstream_gene_variant 0.13
thyA 3074161 p.Pro104Leu missense_variant 0.15
thyA 3074199 c.273G>T synonymous_variant 0.17
thyA 3074297 p.Leu59Met missense_variant 0.2
ald 3086656 c.-164A>T upstream_gene_variant 0.5
ald 3087542 c.723G>T synonymous_variant 0.17
ald 3087632 p.Gln271His missense_variant 0.18
fbiD 3339120 c.3G>T start_lost 0.25
fbiD 3339637 p.Gly174Cys missense_variant 0.14
fbiD 3339738 c.621C>A synonymous_variant 0.15
fbiD 3339742 c.625C>A synonymous_variant 0.15
fprA 3473818 c.-188delA upstream_gene_variant 0.13
fprA 3474991 p.Thr329Ala missense_variant 0.15
Rv3236c 3612145 c.972G>C synonymous_variant 0.12
Rv3236c 3612165 p.Val318Leu missense_variant 0.17
Rv3236c 3612196 c.921C>A synonymous_variant 0.25
Rv3236c 3612462 p.Leu219Met missense_variant 0.17
Rv3236c 3613298 c.-182G>A upstream_gene_variant 0.23
fbiB 3640620 c.-915C>A upstream_gene_variant 0.15
fbiA 3641062 p.Val174Met missense_variant 0.17
fbiA 3641093 p.Ser184Ile missense_variant 0.17
fbiB 3641811 c.277T>C synonymous_variant 0.13
alr 3840461 c.960G>T synonymous_variant 0.33
alr 3840627 p.Ala265Asp missense_variant 0.18
alr 3841261 p.Glu54Lys missense_variant 0.14
rpoA 3878036 p.Glu158* stop_gained 0.14
ddn 3986851 p.Lys3Arg missense_variant 0.17
ddn 3986946 p.Glu35* stop_gained 0.13
ddn 3987286 p.Val148Ala missense_variant 0.11
clpC1 4038394 p.Arg771Ser missense_variant 0.14
clpC1 4039568 p.Met379Ile missense_variant 0.18
clpC1 4040358 p.Gly116Val missense_variant 0.22
panD 4044327 c.-46G>A upstream_gene_variant 0.18
embC 4240697 p.Ala279Ser missense_variant 0.18
embC 4240806 p.Arg315Leu missense_variant 0.15
embC 4241054 p.Pro398Thr missense_variant 0.18
embC 4241411 p.Ile517Leu missense_variant 0.13
embC 4242128 c.2266C>T synonymous_variant 0.2
embC 4242366 p.Ser835Tyr missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243776 p.Gln182Lys missense_variant 0.12
embA 4244184 p.Ser318Leu missense_variant 0.12
embA 4244538 p.Ala436Ser missense_variant 0.15
embA 4245056 c.1824C>A synonymous_variant 0.14
embA 4245188 c.1956G>T synonymous_variant 0.15
embA 4246218 p.His996Asn missense_variant 0.22
embB 4246544 p.Thr11Pro missense_variant 0.43
embB 4247108 p.Gly199Trp missense_variant 0.13
embB 4247821 c.1308T>C synonymous_variant 0.13
embB 4247970 c.1458dupC frameshift_variant 0.12
embB 4247987 p.Val492Leu missense_variant 0.13
embB 4249049 p.Gly846Cys missense_variant 0.33
embB 4249124 p.Gly871Trp missense_variant 0.15
embB 4249265 p.Pro918Ser missense_variant 0.14
embB 4249333 c.2820C>A synonymous_variant 0.15
aftB 4267085 c.1752G>T synonymous_variant 0.22
aftB 4267290 p.Ala516Val missense_variant 0.18
aftB 4267406 p.Lys477Asn missense_variant 0.12
aftB 4267428 p.Ser470* stop_gained 0.17
aftB 4267987 p.Arg284Ser missense_variant 0.5
aftB 4268039 c.798G>T synonymous_variant 0.12
aftB 4268049 p.Pro263Leu missense_variant 0.12
aftB 4268203 p.Leu212Met missense_variant 0.29
ethA 4327532 c.-59G>T upstream_gene_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0