TB-Profiler result

Run: SRR13861304
Summary

Run ID: SRR13861304

Sample name:

Date: 03-04-2023 09:28:34

Number of reads: 576527

Percentage reads mapped: 19.24

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.33 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.83 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5149 c.-91G>C upstream_gene_variant 1.0
gyrB 7090 p.Asp617Glu missense_variant 1.0
gyrA 7658 c.357A>G synonymous_variant 0.17
gyrA 7664 c.363T>C synonymous_variant 0.17
gyrA 7670 c.369A>G synonymous_variant 0.17
gyrA 7676 c.375G>C synonymous_variant 0.15
gyrA 7694 c.393A>G synonymous_variant 0.14
gyrA 7697 c.396C>G synonymous_variant 0.13
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.21
gyrA 7763 c.462T>C synonymous_variant 0.17
gyrA 7799 c.498A>G synonymous_variant 0.19
gyrA 7835 c.534A>G synonymous_variant 0.18
gyrA 7838 c.537C>G synonymous_variant 0.14
gyrA 7859 c.558A>C synonymous_variant 0.14
gyrA 7862 c.561C>G synonymous_variant 0.19
gyrA 7865 c.564T>C synonymous_variant 0.15
gyrA 7883 c.582G>C synonymous_variant 0.15
gyrA 7884 p.Arg195Gly missense_variant 0.16
gyrA 7892 c.591G>C synonymous_variant 0.16
gyrA 8024 c.723T>C synonymous_variant 0.12
gyrA 8036 c.735A>G synonymous_variant 0.18
gyrA 8039 c.738T>C synonymous_variant 0.16
gyrA 8048 c.747C>T synonymous_variant 0.17
gyrA 8054 c.753T>C synonymous_variant 0.15
gyrA 8057 c.756A>G synonymous_variant 0.16
gyrA 8069 c.768T>C synonymous_variant 0.15
gyrA 8078 c.777A>G synonymous_variant 0.14
gyrA 8090 c.789C>G synonymous_variant 0.15
gyrA 8096 c.795T>C synonymous_variant 0.15
gyrA 8099 c.798T>C synonymous_variant 0.15
gyrA 8111 c.810G>C synonymous_variant 0.21
gyrA 8156 c.855T>C synonymous_variant 0.21
gyrA 8168 c.867A>G synonymous_variant 0.2
gyrA 8174 c.873C>G synonymous_variant 0.2
gyrA 8177 c.876A>C synonymous_variant 0.2
gyrA 8198 c.897T>C synonymous_variant 0.16
gyrA 8204 c.903C>T synonymous_variant 0.18
gyrA 8207 c.906T>C synonymous_variant 0.17
gyrA 8216 c.915G>A synonymous_variant 0.17
gyrA 8219 c.918T>C synonymous_variant 0.16
gyrA 8225 c.924T>C synonymous_variant 0.18
gyrA 8264 c.963T>C synonymous_variant 0.12
gyrA 8267 c.966G>C synonymous_variant 0.12
gyrA 8270 c.969G>C synonymous_variant 0.13
gyrA 8366 c.1065G>C synonymous_variant 0.17
gyrA 8375 c.1074G>C synonymous_variant 0.15
gyrA 8436 p.Tyr379Asn missense_variant 0.91
gyrA 9275 c.1974G>A synonymous_variant 0.18
gyrA 9278 c.1977G>C synonymous_variant 0.17
gyrA 9281 c.1980C>G synonymous_variant 0.17
gyrA 9284 c.1983T>C synonymous_variant 0.17
gyrA 9291 c.1990C>T synonymous_variant 0.17
gyrA 9296 c.1995T>C synonymous_variant 0.16
gyrA 9305 c.2004C>G synonymous_variant 0.16
gyrA 9311 c.2010C>T synonymous_variant 0.17
gyrA 9323 c.2022C>G synonymous_variant 0.16
gyrA 9345 c.2044A>C synonymous_variant 0.14
fgd1 491701 p.His307Asn missense_variant 1.0
mshA 575734 c.387T>G synonymous_variant 0.14
mshA 575737 c.390T>C synonymous_variant 0.14
mshA 575746 c.399C>G synonymous_variant 0.15
mshA 575752 c.405G>A synonymous_variant 0.15
ccsA 619765 c.-126G>A upstream_gene_variant 1.0
ccsA 620349 c.459A>G synonymous_variant 0.12
rpoB 761222 c.1416G>C synonymous_variant 0.15
rpoC 762443 c.-927G>C upstream_gene_variant 0.14
rpoC 762470 c.-900G>C upstream_gene_variant 0.18
rpoB 762489 p.Val895His missense_variant 0.15
rpoC 762989 c.-381G>C upstream_gene_variant 0.15
rpoC 762995 c.-375G>T upstream_gene_variant 0.16
rpoC 763835 p.Ala156Thr missense_variant 0.13
rpoC 763945 c.576T>C synonymous_variant 0.16
rpoC 763960 c.591T>C synonymous_variant 0.15
rpoC 763967 p.Gly200Ser missense_variant 0.15
rpoC 764431 c.1062G>C synonymous_variant 0.14
rpoC 764434 c.1065A>G synonymous_variant 0.14
rpoC 764446 c.1077T>C synonymous_variant 0.16
rpoC 764449 c.1080G>C synonymous_variant 0.17
rpoC 764455 c.1086G>C synonymous_variant 0.17
rpoC 764458 c.1089G>C synonymous_variant 0.18
rpoC 764461 c.1092A>G synonymous_variant 0.19
rpoC 764497 c.1128A>G synonymous_variant 0.16
rpoC 764521 c.1152T>C synonymous_variant 0.15
rpoC 764530 c.1161C>G synonymous_variant 0.16
rpoC 764560 c.1191T>C synonymous_variant 0.14
rpoC 764566 c.1197C>G synonymous_variant 0.13
rpoC 765541 c.2172C>G synonymous_variant 0.13
rpoC 765553 c.2184C>T synonymous_variant 0.14
rpoC 765556 c.2187G>C synonymous_variant 0.14
rpoC 765559 c.2190G>C synonymous_variant 0.14
rpoC 765578 c.2209C>T synonymous_variant 0.13
rpoC 766933 c.3564A>G synonymous_variant 0.15
rpoC 766945 c.3576A>G synonymous_variant 0.15
rpoC 766963 c.3594T>C synonymous_variant 0.16
rpoC 766978 c.3609C>G synonymous_variant 0.17
rpoC 766996 c.3627C>T synonymous_variant 0.15
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.15
rpoC 767014 c.3645G>C synonymous_variant 0.15
rpoC 767033 p.Ser1222Thr missense_variant 0.14
rpoC 767059 c.3690T>G synonymous_variant 0.23
rpoC 767062 c.3693C>A synonymous_variant 0.24
rpoC 767074 c.3705T>C synonymous_variant 0.24
rpoC 767098 c.3729T>C synonymous_variant 0.22
rpoC 767119 c.3750A>G synonymous_variant 0.19
rpoC 767134 c.3765C>G synonymous_variant 0.21
rpoC 767158 c.3789T>C synonymous_variant 0.19
rpoC 767167 c.3798C>G synonymous_variant 0.19
rpoC 767180 p.Ala1271Gln missense_variant 0.17
mmpL5 775867 p.Arg872Gly missense_variant 0.95
mmpL5 776710 p.Cys591Ser missense_variant 1.0
mmpL5 777625 p.Gln286Lys missense_variant 1.0
mmpS5 778811 p.Phe32Ser missense_variant 1.0
rpsL 781631 c.72G>C synonymous_variant 0.14
rpsL 781655 c.96T>C synonymous_variant 0.18
rpsL 781682 c.123T>C synonymous_variant 0.2
rpsL 781715 c.156T>C synonymous_variant 0.22
rpsL 781728 c.169T>C synonymous_variant 0.22
rpsL 781736 c.177T>C synonymous_variant 0.18
rpsL 781751 c.192G>C synonymous_variant 0.18
rpsL 781754 c.195G>C synonymous_variant 0.19
rpsL 781760 c.201T>C synonymous_variant 0.19
rpsL 781793 c.234G>C synonymous_variant 0.2
rpsL 781832 c.273T>C synonymous_variant 0.17
rpsL 781841 c.282C>G synonymous_variant 0.25
rpsL 781859 c.300T>C synonymous_variant 0.33
rpsL 781868 c.309T>C synonymous_variant 0.23
rpsL 781871 c.312G>C synonymous_variant 0.23
rpsL 781892 c.333A>G synonymous_variant 0.25
rpsL 781898 c.339A>T synonymous_variant 0.25
rpsL 781916 c.357T>C synonymous_variant 0.23
rpsL 781929 p.Gly124Ser missense_variant 0.14
rplC 800648 c.-161A>C upstream_gene_variant 0.16
fbiC 1305303 c.2373T>C synonymous_variant 0.14
fbiC 1305311 p.Arg794Gln missense_variant 0.14
fbiC 1305331 p.Glu801Asn missense_variant 0.15
fbiC 1305336 c.2406T>C synonymous_variant 0.15
embR 1416901 c.447G>C synonymous_variant 1.0
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.18
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.18
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.25
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.27
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.21
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.21
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.21
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.21
rrs 1472044 n.199G>C non_coding_transcript_exon_variant 0.25
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.19
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.24
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.28
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.15
rrs 1472101 n.256G>A non_coding_transcript_exon_variant 0.29
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.29
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.57
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.66
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.55
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.7
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.7
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.67
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.7
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.72
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.69
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.68
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.7
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.71
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.7
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.72
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.72
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.71
rrs 1472230 n.385C>T non_coding_transcript_exon_variant 0.29
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.68
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.68
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.67
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.55
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 0.47
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.36
rrs 1472262 n.417C>T non_coding_transcript_exon_variant 0.32
rrs 1472269 n.424G>A non_coding_transcript_exon_variant 0.15
rrs 1472271 n.426T>C non_coding_transcript_exon_variant 0.15
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.24
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.4
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.7
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.7
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.68
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.7
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.7
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.7
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.73
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.75
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.79
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.77
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.79
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.77
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.73
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.73
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.81
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.83
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.87
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.85
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.85
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.86
rrs 1472669 n.824_825insTAGG non_coding_transcript_exon_variant 0.88
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.88
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.87
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.84
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.84
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.83
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.83
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.53
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.38
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.34
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.36
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.38
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.39
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.38
rrs 1473260 n.1415G>T non_coding_transcript_exon_variant 0.38
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.39
rrs 1473281 n.1436C>A non_coding_transcript_exon_variant 0.39
rrs 1473282 n.1437C>G non_coding_transcript_exon_variant 0.37
rrs 1473288 n.1443C>A non_coding_transcript_exon_variant 0.43
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.43
rrs 1473291 n.1446G>T non_coding_transcript_exon_variant 0.39
rrs 1473296 n.1451G>C non_coding_transcript_exon_variant 0.39
rrs 1473297 n.1452G>T non_coding_transcript_exon_variant 0.39
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.39
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.39
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.4
rrs 1473352 n.1507C>T non_coding_transcript_exon_variant 0.43
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.25
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.26
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.27
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.24
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.23
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.23
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.2
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.21
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.17
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.19
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.19
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.19
rrl 1474051 n.394T>C non_coding_transcript_exon_variant 0.14
rrl 1474054 n.397T>C non_coding_transcript_exon_variant 0.14
rrl 1474056 n.399T>C non_coding_transcript_exon_variant 0.14
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.16
rrl 1474466 n.810delA non_coding_transcript_exon_variant 1.0
rrl 1475224 n.1567T>C non_coding_transcript_exon_variant 1.0
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.18
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.18
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 0.17
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.16
rrl 1475369 n.1712G>C non_coding_transcript_exon_variant 0.17
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.2
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.18
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.18
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.19
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.15
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.19
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.17
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.68
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.73
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.84
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.83
rrl 1476263 n.2606C>T non_coding_transcript_exon_variant 0.16
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.82
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.81
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.82
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.81
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.82
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.83
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.83
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.83
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.83
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.82
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.82
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.84
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.85
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.86
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.92
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.93
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.94
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.94
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.94
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.94
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.75
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.94
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.95
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.95
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.95
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.96
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.95
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.92
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.86
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.84
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.83
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.84
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.84
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.83
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.82
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.82
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.82
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.82
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.83
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.8
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.8
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.8
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.78
rrl 1476589 n.2932G>A non_coding_transcript_exon_variant 0.25
rrl 1476595 n.2938C>G non_coding_transcript_exon_variant 0.32
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.17
inhA 1673589 c.-613A>G upstream_gene_variant 0.12
fabG1 1673598 p.Lys53Asn missense_variant 0.12
rpsA 1833724 c.183C>G synonymous_variant 0.14
PPE35 2170487 c.126T>A synonymous_variant 1.0
Rv1979c 2221853 p.Phe438Ile missense_variant 1.0
kasA 2518413 p.Ser100Asn missense_variant 0.17
kasA 2518421 p.Val103Leu missense_variant 0.17
kasA 2518426 c.312T>C synonymous_variant 0.15
kasA 2518429 c.315A>C synonymous_variant 0.15
kasA 2518439 p.Ala109Ser missense_variant 0.15
kasA 2518444 c.330T>C synonymous_variant 0.15
kasA 2518447 c.333T>G synonymous_variant 0.18
kasA 2518450 c.336C>G synonymous_variant 0.18
kasA 2518459 c.345T>C synonymous_variant 0.18
kasA 2518462 c.348A>C synonymous_variant 0.18
kasA 2518468 c.354A>T synonymous_variant 0.21
kasA 2518475 c.361A>C synonymous_variant 0.21
kasA 2518480 c.366T>C synonymous_variant 0.21
kasA 2518483 c.369C>G synonymous_variant 0.21
kasA 2518504 c.390T>C synonymous_variant 0.23
kasA 2518506 p.Ala131Glu missense_variant 0.23
kasA 2518513 c.399C>G synonymous_variant 0.25
kasA 2518519 c.405G>C synonymous_variant 0.29
kasA 2518528 c.414C>G synonymous_variant 0.25
kasA 2518540 c.426T>G synonymous_variant 0.28
kasA 2518561 c.447T>C synonymous_variant 0.21
kasA 2518567 c.453G>C synonymous_variant 0.21
kasA 2518570 c.456G>C synonymous_variant 0.21
kasA 2518574 p.Ile154Val missense_variant 0.23
kasA 2518588 c.474T>C synonymous_variant 0.36
kasA 2518591 c.477G>C synonymous_variant 0.33
kasA 2518609 p.Met165Ile missense_variant 0.29
kasA 2518621 c.507G>A synonymous_variant 0.33
kasA 2518642 c.528A>G synonymous_variant 0.29
kasA 2518663 c.549T>C synonymous_variant 0.26
kasA 2518672 c.558G>C synonymous_variant 0.24
kasA 2518687 c.573C>T synonymous_variant 0.17
kasA 2518696 c.582C>G synonymous_variant 0.17
kasA 2518702 c.588C>T synonymous_variant 0.15
ribD 2987369 c.531G>A synonymous_variant 1.0
thyA 3073872 p.Ile200Met missense_variant 0.14
thyA 3073878 c.594G>A synonymous_variant 0.14
thyA 3073892 c.580T>C synonymous_variant 0.15
thyA 3073893 c.579C>G synonymous_variant 0.15
thyA 3073925 c.547T>C synonymous_variant 0.19
thyA 3073926 c.546G>C synonymous_variant 0.2
thyA 3073929 c.543T>C synonymous_variant 0.19
thyA 3073953 c.519T>C synonymous_variant 0.27
thyA 3073975 p.Arg166Pro missense_variant 0.76
thyA 3073977 c.495A>G synonymous_variant 0.24
thyA 3073989 c.483T>C synonymous_variant 0.24
thyA 3074001 c.471C>G synonymous_variant 0.25
thyA 3074004 c.468T>C synonymous_variant 0.23
thyA 3074010 c.462C>G synonymous_variant 0.31
thyA 3074031 c.441T>C synonymous_variant 0.25
thyA 3074037 c.435C>G synonymous_variant 0.25
thyA 3074056 p.Glu139Pro missense_variant 0.21
thyA 3074061 c.411A>G synonymous_variant 0.21
thyA 3074076 c.396C>G synonymous_variant 0.25
thyA 3074097 c.375C>G synonymous_variant 0.18
thyA 3074100 c.372T>C synonymous_variant 0.2
thyA 3074106 c.366T>C synonymous_variant 0.2
Rv3236c 3612013 c.1104A>T synonymous_variant 1.0
Rv3236c 3612032 p.Met362Arg missense_variant 1.0
fbiB 3642560 c.1026T>C synonymous_variant 0.17
fbiB 3642566 c.1032A>G synonymous_variant 0.16
fbiB 3642581 c.1047A>C synonymous_variant 0.17
fbiB 3642593 c.1059G>C synonymous_variant 0.15
fbiB 3642602 c.1068A>C synonymous_variant 0.2
fbiB 3642605 c.1071A>G synonymous_variant 0.2
fbiB 3642614 c.1080C>T synonymous_variant 0.26
fbiB 3642620 c.1086T>C synonymous_variant 0.26
fbiB 3642656 c.1122G>C synonymous_variant 0.23
fbiB 3642659 c.1125C>G synonymous_variant 0.23
fbiB 3642662 c.1128C>G synonymous_variant 0.23
fbiB 3642668 c.1134A>C synonymous_variant 0.24
fbiB 3642677 c.1143A>G synonymous_variant 0.23
fbiB 3642680 c.1146A>G synonymous_variant 0.23
fbiB 3642684 c.1150T>C synonymous_variant 0.23
fbiB 3642694 p.Ala387Gly missense_variant 0.18
fbiB 3642696 c.1162C>T synonymous_variant 0.19
fbiB 3642701 c.1167C>G synonymous_variant 0.19
fbiB 3642710 c.1176G>C synonymous_variant 0.19
fbiB 3642719 c.1185T>C synonymous_variant 0.2
fbiB 3642734 c.1200G>C synonymous_variant 0.2
fbiB 3642743 c.1209T>C synonymous_variant 0.2
rpoA 3878022 c.486T>C synonymous_variant 0.12
rpoA 3878031 c.477T>C synonymous_variant 0.17
rpoA 3878040 c.468T>C synonymous_variant 0.2
rpoA 3878046 c.462T>C synonymous_variant 0.18
rpoA 3878049 c.459G>C synonymous_variant 0.19
rpoA 3878055 c.453A>G synonymous_variant 0.21
rpoA 3878061 c.447G>C synonymous_variant 0.24
rpoA 3878067 c.441C>G synonymous_variant 0.21
rpoA 3878070 c.438T>C synonymous_variant 0.21
rpoA 3878082 c.426T>C synonymous_variant 0.2
rpoA 3878094 c.414C>G synonymous_variant 0.15
rpoA 3878100 c.408C>G synonymous_variant 0.16
rpoA 3878103 c.405A>G synonymous_variant 0.17
rpoA 3878106 c.402G>C synonymous_variant 0.17
rpoA 3878118 c.390T>C synonymous_variant 0.17
rpoA 3878141 p.Met123Leu missense_variant 0.17
rpoA 3878142 p.Gly122Glu missense_variant 0.16
clpC1 4038398 c.2307G>T synonymous_variant 0.21
clpC1 4038403 c.2302T>C synonymous_variant 0.17
clpC1 4038419 c.2286T>C synonymous_variant 0.17
clpC1 4038434 c.2271G>C synonymous_variant 0.15
clpC1 4039430 c.1275T>C synonymous_variant 0.17
clpC1 4039442 c.1263A>G synonymous_variant 0.18
clpC1 4039448 c.1257A>G synonymous_variant 0.17
clpC1 4039454 c.1251A>G synonymous_variant 0.17
clpC1 4039463 c.1242C>G synonymous_variant 0.16
clpC1 4039466 c.1239T>C synonymous_variant 0.15
clpC1 4039469 c.1236T>C synonymous_variant 0.16
clpC1 4039481 c.1224T>G synonymous_variant 0.16
clpC1 4039484 c.1221T>G synonymous_variant 0.15
clpC1 4039517 c.1188C>G synonymous_variant 0.15
clpC1 4039524 p.Phe394Tyr missense_variant 0.19
clpC1 4039526 c.1179G>C synonymous_variant 0.18
clpC1 4039547 c.1158C>G synonymous_variant 0.21
clpC1 4039553 c.1152C>G synonymous_variant 0.25
clpC1 4039562 c.1143C>G synonymous_variant 0.17
clpC1 4039565 c.1140G>C synonymous_variant 0.17
clpC1 4039576 p.Ala377Ser missense_variant 0.16
clpC1 4039577 c.1128T>C synonymous_variant 0.16
clpC1 4039586 c.1119G>C synonymous_variant 0.16
clpC1 4039610 c.1095G>C synonymous_variant 0.14
clpC1 4039616 c.1089G>C synonymous_variant 0.15
clpC1 4039724 c.981A>G synonymous_variant 0.17
clpC1 4039748 c.957G>C synonymous_variant 0.16
clpC1 4039751 c.954A>G synonymous_variant 0.15
clpC1 4039757 c.948A>G synonymous_variant 0.17
clpC1 4039760 c.945T>C synonymous_variant 0.17
clpC1 4039766 c.939T>C synonymous_variant 0.17
clpC1 4039769 c.936C>G synonymous_variant 0.17
clpC1 4039778 c.927A>G synonymous_variant 0.18
clpC1 4039781 c.924G>C synonymous_variant 0.23
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.17
clpC1 4039793 c.912C>G synonymous_variant 0.17
clpC1 4039817 c.888A>T synonymous_variant 0.17
clpC1 4039820 c.885T>G synonymous_variant 0.17
clpC1 4039831 c.874T>C synonymous_variant 0.14
clpC1 4039832 c.873C>G synonymous_variant 0.14
clpC1 4039850 c.855T>C synonymous_variant 0.17
clpC1 4039865 c.840T>C synonymous_variant 0.17
clpC1 4039898 c.807C>G synonymous_variant 0.17
clpC1 4039904 c.801A>G synonymous_variant 0.17
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.17
clpC1 4039931 c.774T>C synonymous_variant 0.17
clpC1 4039946 c.759A>T synonymous_variant 0.16
clpC1 4039952 c.753T>C synonymous_variant 0.16
clpC1 4039958 c.747G>C synonymous_variant 0.15
clpC1 4039979 c.726C>G synonymous_variant 0.16
clpC1 4039996 p.Glu237Gln missense_variant 0.13
clpC1 4040546 c.159G>C synonymous_variant 0.14
clpC1 4040551 c.154T>C synonymous_variant 0.14
embC 4240425 p.Arg188Pro missense_variant 1.0
embC 4240477 c.615C>A synonymous_variant 1.0
embC 4240780 c.918T>C synonymous_variant 0.14
embC 4240783 c.921G>C synonymous_variant 0.12
embC 4240789 c.927T>C synonymous_variant 0.12
embC 4240819 c.957A>G synonymous_variant 0.15
embC 4241023 c.1161T>G synonymous_variant 0.17
embC 4241026 c.1164C>G synonymous_variant 0.15
embC 4241035 c.1173G>A synonymous_variant 0.18
embC 4241050 c.1188T>G synonymous_variant 0.18
embC 4241104 c.1242G>A synonymous_variant 0.17
embC 4241107 c.1245G>C synonymous_variant 0.17
embC 4241137 c.1275G>C synonymous_variant 0.15
embC 4241140 c.1278A>G synonymous_variant 0.15
embC 4241141 p.Ile427Val missense_variant 0.15
embC 4241158 c.1296T>C synonymous_variant 0.14
embC 4241161 c.1299C>G synonymous_variant 0.14
embC 4241162 c.1300T>C synonymous_variant 0.13
embC 4241233 c.1371G>C synonymous_variant 0.13
embA 4244214 p.Ala328Ser missense_variant 1.0
embA 4244849 c.1617C>G synonymous_variant 1.0
embA 4245038 c.1806C>T synonymous_variant 0.16
embA 4245056 c.1824C>G synonymous_variant 0.17
embA 4245077 c.1845G>C synonymous_variant 0.14
embB 4245807 c.-707_-705delTTAinsCTG upstream_gene_variant 0.18
embA 4245820 p.Ser863Thr missense_variant 0.17
embB 4245830 c.-684G>C upstream_gene_variant 0.15
embB 4245845 c.-669T>G upstream_gene_variant 0.17
embB 4245848 c.-666C>G upstream_gene_variant 0.17
embB 4247198 p.Thr229Pro missense_variant 1.0
embB 4247381 p.Trp290Arg missense_variant 0.96
embB 4249483 c.2970C>G synonymous_variant 0.12
embB 4249486 c.2973T>G synonymous_variant 0.12
embB 4249487 c.2974T>C synonymous_variant 0.12
aftB 4268115 p.Leu241Arg missense_variant 1.0
aftB 4268696 c.141G>A synonymous_variant 1.0
ethA 4326298 c.1176G>A synonymous_variant 1.0
whiB6 4338567 c.-46C>A upstream_gene_variant 1.0