TB-Profiler result

Run: ERR11465829
Summary

Run ID: ERR11465829

Sample name:

Date: 10-01-2024 04:26:45

Number of reads: 1635650

Percentage reads mapped: 99.62

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575761 c.414C>T synonymous_variant 1.0
rpoB 759814 p.Asp3Gly missense_variant 1.0
rpoC 763495 c.126G>A synonymous_variant 0.19
rpoC 763504 c.135C>G synonymous_variant 0.12
rpoC 763507 c.138G>C synonymous_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781502 c.-58G>T upstream_gene_variant 1.0
rpsL 781793 c.234G>C synonymous_variant 0.17
rpsL 781796 p.Met79Ile missense_variant 0.16
rpsL 781802 c.243G>C synonymous_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.12
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.14
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.14
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.14
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.14
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.18
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.13
rrs 1472793 n.948A>C non_coding_transcript_exon_variant 0.13
rrs 1472803 n.958T>C non_coding_transcript_exon_variant 0.16
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.22
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.17
rrs 1473062 n.1217T>G non_coding_transcript_exon_variant 0.15
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.14
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.24
rrs 1473091 n.1246G>A non_coding_transcript_exon_variant 0.23
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.15
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.13
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.14
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.17
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.16
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.19
rrl 1474662 n.1005C>G non_coding_transcript_exon_variant 0.13
rrl 1474676 n.1019T>C non_coding_transcript_exon_variant 0.16
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.16
rrl 1474688 n.1031G>C non_coding_transcript_exon_variant 0.16
rrl 1474690 n.1033C>T non_coding_transcript_exon_variant 0.16
rrl 1474722 n.1065T>C non_coding_transcript_exon_variant 0.13
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.23
rrl 1474736 n.1079C>T non_coding_transcript_exon_variant 0.23
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.14
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.16
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.12
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.21
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.15
rrl 1474896 n.1239A>T non_coding_transcript_exon_variant 0.23
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.19
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.19
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.22
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.11
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.11
rrl 1475883 n.2226A>G non_coding_transcript_exon_variant 0.25
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.13
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.14
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.14
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.17
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.12
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.13
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.14
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.25
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.24
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.24
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.15
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.15
rpsA 1833952 c.411C>T synonymous_variant 0.12
rpsA 1833955 c.414G>C synonymous_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv2752c 3065873 p.Phe107Val missense_variant 1.0
clpC1 4040063 c.642G>C synonymous_variant 0.19
whiB6 4338595 c.-75delG upstream_gene_variant 1.0