TB-Profiler result

Run: ERR4821747
Summary

Run ID: ERR4821747

Sample name:

Date: 01-04-2023 17:25:52

Number of reads: 189973

Percentage reads mapped: 4.15

Strain: lineage4.9;lineage4.2.1

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.96
lineage4.2.1 Euro-American (TUR) H3;H4 None 0.08
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 1.0 rifampicin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.86 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 1.0 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155693 p.Ser140Asn missense_variant 0.75 isoniazid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 8923 p.Gly541Val missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575953 c.606G>A synonymous_variant 0.67
rpoB 760208 p.Ile134Met missense_variant 1.0
rpoB 760212 p.Asn136His missense_variant 1.0
rpoB 760215 p.Asn137Gln missense_variant 1.0
rpoB 760234 p.Ser143Thr missense_variant 1.0
rpoB 760244 c.438G>C synonymous_variant 1.0
rpoB 760253 c.447T>C synonymous_variant 1.0
rpoB 760263 p.Met153Leu missense_variant 1.0
rpoB 760266 p.Met154Gln missense_variant 1.0
rpoB 760274 p.Glu156Asp missense_variant 1.0
rpoB 760298 c.492G>C synonymous_variant 1.0
rpoB 760997 c.1191G>C synonymous_variant 1.0
rpoB 761006 c.1200C>G synonymous_variant 1.0
rpoB 761013 p.Val403Ile missense_variant 1.0
rpoB 761027 c.1221A>G synonymous_variant 1.0
rpoB 761036 c.1230G>C synonymous_variant 1.0
rpoB 761037 c.1231T>C synonymous_variant 1.0
rpoB 761046 p.Ile414Val missense_variant 1.0
rpoB 761051 c.1245G>T synonymous_variant 1.0
rpoB 761054 c.1248G>C synonymous_variant 1.0
rpoB 761057 c.1251G>C synonymous_variant 1.0
rpoB 761060 c.1254C>G synonymous_variant 1.0
rpoB 761063 c.1257C>G synonymous_variant 1.0
rpoB 761084 c.1278C>A synonymous_variant 1.0
rpoB 761088 c.1282_1284delAGCinsTCG synonymous_variant 1.0
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 1.0
rpoB 761102 c.1296A>G synonymous_variant 1.0
rpoB 761126 c.1320G>C synonymous_variant 1.0
rpoB 761132 c.1326G>T synonymous_variant 1.0
rpoB 761133 c.1327T>C synonymous_variant 1.0
rpoB 761147 c.1341C>T synonymous_variant 1.0
rpoB 761150 c.1344A>T synonymous_variant 1.0
rpoB 761165 c.1359G>C synonymous_variant 1.0
rpoB 761180 c.1374A>G synonymous_variant 0.75
rpoB 761189 c.1383T>C synonymous_variant 0.75
rpoB 761195 c.1389G>C synonymous_variant 0.6
rpoB 761196 p.Leu464Val missense_variant 0.6
rpoB 761207 c.1401C>T synonymous_variant 0.6
rpoB 761213 c.1407G>C synonymous_variant 0.5
rpoB 761219 c.1413G>C synonymous_variant 0.43
rpoB 762879 p.Met1025Leu missense_variant 0.89
rpoC 762896 c.-474G>C upstream_gene_variant 0.94
rpoC 762917 c.-453C>G upstream_gene_variant 0.98
rpoC 762929 c.-441G>T upstream_gene_variant 0.94
rpoC 762947 c.-423C>G upstream_gene_variant 0.95
rpoC 762962 c.-408C>T upstream_gene_variant 0.95
rpoC 762980 c.-390T>C upstream_gene_variant 0.93
rpoC 762989 c.-381G>C upstream_gene_variant 0.9
rpoC 762995 c.-375G>T upstream_gene_variant 0.88
rpoC 763028 c.-342T>C upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 1.0
rpoC 763052 c.-318G>C upstream_gene_variant 1.0
rpoC 763053 c.-317_-315delTTGinsCTC upstream_gene_variant 1.0
rpoC 763058 c.-312C>G upstream_gene_variant 1.0
rpoC 763070 c.-300T>C upstream_gene_variant 1.0
rpoB 763075 p.Thr1090Ile missense_variant 1.0
rpoB 763077 p.Val1091Leu missense_variant 1.0
rpoC 763115 c.-255T>C upstream_gene_variant 0.97
rpoB 763126 p.Pro1107Gln missense_variant 0.96
rpoC 763133 c.-237G>C upstream_gene_variant 0.95
rpoC 763136 c.-234C>T upstream_gene_variant 0.95
rpoC 763148 c.-222G>C upstream_gene_variant 0.93
rpoC 763443 p.Tyr25Phe missense_variant 1.0
rpoC 763456 c.87A>G synonymous_variant 1.0
rpoC 763462 c.93G>C synonymous_variant 1.0
rpoC 763483 c.114G>C synonymous_variant 1.0
rpoC 763486 c.117T>G synonymous_variant 0.95
rpoC 763492 c.123G>C synonymous_variant 0.95
rpoC 763504 c.135C>T synonymous_variant 0.96
rpoC 763511 p.Cys48Gly missense_variant 0.95
rpoC 763517 p.Lys50Gln missense_variant 0.96
rpoC 763528 c.159G>A synonymous_variant 0.96
rpoC 763531 c.162G>C synonymous_variant 0.96
rpoC 763532 p.Thr55Ser missense_variant 0.96
rpoC 763546 c.177A>G synonymous_variant 0.96
rpoC 763550 p.Tyr61Ala missense_variant 0.93
rpoC 763570 c.201G>C synonymous_variant 0.88
rpoC 763573 c.204G>C synonymous_variant 0.88
rpoC 763589 p.Ile74Val missense_variant 0.94
rpoC 763609 c.240C>G synonymous_variant 0.88
rpoC 763614 c.246_251delGACCCG disruptive_inframe_deletion 0.67
rpoC 763622 p.Ala85Thr missense_variant 0.67
rpoC 763627 c.258_259insAGCTCC conservative_inframe_insertion 0.67
rpoC 763630 c.261G>C synonymous_variant 0.67
rpoC 763633 c.264T>C synonymous_variant 0.67
rpoC 763636 c.267T>C synonymous_variant 0.67
rpoC 763642 c.273G>C synonymous_variant 0.78
rpoC 763660 c.291T>C synonymous_variant 0.92
rpoC 763696 c.327T>C synonymous_variant 0.93
rpoC 763699 c.330G>C synonymous_variant 0.93
rpoC 763708 c.339G>C synonymous_variant 0.93
rpoC 763709 c.340C>T synonymous_variant 0.93
rpoC 763714 c.345G>C synonymous_variant 0.93
rpoC 763717 c.348T>C synonymous_variant 0.93
rpoC 763723 c.354G>C synonymous_variant 0.93
rpoC 763727 p.Leu120Met missense_variant 0.93
rpoC 763732 c.363C>G synonymous_variant 0.93
rpoC 763744 c.375G>C synonymous_variant 0.89
rpoC 763751 p.Ile128Val missense_variant 0.91
rpoC 763765 c.396T>C synonymous_variant 0.79
rpoC 763772 p.Val135Met missense_variant 0.5
rpoC 764344 c.975C>T synonymous_variant 1.0
rpoC 764353 c.984G>C synonymous_variant 1.0
rpoC 764371 c.1002G>C synonymous_variant 1.0
rpoC 764380 c.1011G>C synonymous_variant 1.0
rpoC 764381 c.1012_1013delTCinsAG synonymous_variant 1.0
rpoC 764387 c.1018T>C synonymous_variant 1.0
rpoC 764398 c.1029G>C synonymous_variant 0.8
rpoC 764404 c.1035C>T synonymous_variant 0.8
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.8
rpoC 764582 p.Leu405Met missense_variant 0.88
rpoC 764587 c.1218C>G synonymous_variant 0.89
rpoC 764593 c.1224C>T synonymous_variant 0.95
rpoC 764602 c.1233C>T synonymous_variant 0.97
rpoC 764611 c.1242G>T synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 0.98
rpoC 764650 c.1281G>T synonymous_variant 0.99
rpoC 764660 p.Val431Ile missense_variant 0.99
rpoC 764692 c.1323C>T synonymous_variant 0.96
rpoC 764706 p.Leu446Gln missense_variant 0.95
rpoC 764713 c.1344G>C synonymous_variant 0.94
rpoC 764740 p.Met457Ile missense_variant 0.7
rpoC 764746 c.1377G>C synonymous_variant 0.62
rpoC 764750 p.Val461Ile missense_variant 0.5
rpoC 765376 c.2007C>T synonymous_variant 0.67
mmpL5 776638 p.Glu615Lys missense_variant 0.67
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781407 c.-153C>A upstream_gene_variant 0.67
rpsL 781751 c.192G>C synonymous_variant 0.83
rpsL 781754 c.195G>C synonymous_variant 0.92
rpsL 781760 c.201T>C synonymous_variant 0.89
rpsL 781794 p.Met79Leu missense_variant 0.9
rpsL 781814 c.255C>T synonymous_variant 0.96
rpsL 781817 c.258G>T synonymous_variant 0.96
rpsL 781829 c.270G>C synonymous_variant 0.96
rpsL 781832 c.273T>C synonymous_variant 0.96
rpsL 781841 c.282C>T synonymous_variant 0.95
rpsL 781851 p.Ile98Val missense_variant 0.83
rplC 800672 c.-137G>C upstream_gene_variant 0.67
rplC 800693 c.-116A>C upstream_gene_variant 0.67
rplC 800702 c.-107G>C upstream_gene_variant 0.67
rplC 800703 c.-106_-104delTTGinsCTC upstream_gene_variant 0.67
rplC 800720 c.-89T>C upstream_gene_variant 0.55
rplC 800723 c.-86C>G upstream_gene_variant 0.5
rplC 800729 c.-80G>C upstream_gene_variant 0.55
rplC 800733 c.-76A>G upstream_gene_variant 0.55
rplC 800738 c.-71T>C upstream_gene_variant 0.55
rplC 800742 c.-67G>T upstream_gene_variant 0.55
rplC 800747 c.-62C>G upstream_gene_variant 0.55
rplC 800753 c.-56C>T upstream_gene_variant 0.38
rplC 800754 c.-55A>C upstream_gene_variant 0.38
embR 1417524 c.-177G>T upstream_gene_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.8
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.8
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.8
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.8
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.8
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.86
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472284 n.439C>T non_coding_transcript_exon_variant 1.0
rrs 1472571 n.726G>A non_coding_transcript_exon_variant 0.67
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.67
rrs 1472606 n.761C>G non_coding_transcript_exon_variant 1.0
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 1.0
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 1.0
rrs 1472645 n.800G>C non_coding_transcript_exon_variant 1.0
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 1.0
rrs 1472660 n.815T>A non_coding_transcript_exon_variant 1.0
rrs 1472666 n.821G>T non_coding_transcript_exon_variant 1.0
rrs 1472694 n.849C>A non_coding_transcript_exon_variant 1.0
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 1.0
rrs 1472714 n.869A>T non_coding_transcript_exon_variant 1.0
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.75
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.75
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.75
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 1.0
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 1.0
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 1.0
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 1.0
rrs 1472982 n.1137G>A non_coding_transcript_exon_variant 1.0
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 1.0
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 1.0
rrs 1472993 n.1148G>T non_coding_transcript_exon_variant 1.0
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 1.0
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 1.0
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 1.0
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 1.0
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 1.0
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 1.0
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 1.0
rrs 1473134 n.1289T>C non_coding_transcript_exon_variant 1.0
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0
rrs 1473147 n.1302G>A non_coding_transcript_exon_variant 1.0
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.71
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.78
rrs 1473226 n.1381C>T non_coding_transcript_exon_variant 0.8
rrs 1473269 n.1424C>T non_coding_transcript_exon_variant 1.0
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0
rrs 1473291 n.1446_1447insT non_coding_transcript_exon_variant 1.0
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 1.0
rrs 1473320 n.1475G>A non_coding_transcript_exon_variant 1.0
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 1.0
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 1.0
rrl 1474351 n.694G>C non_coding_transcript_exon_variant 1.0
rrl 1474354 n.697C>T non_coding_transcript_exon_variant 1.0
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 1.0
rrl 1474359 n.702C>G non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 1.0
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 1.0
rrl 1474496 n.839C>A non_coding_transcript_exon_variant 1.0
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 1.0
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 1.0
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 1.0
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 1.0
rrl 1474601 n.944C>T non_coding_transcript_exon_variant 1.0
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 1.0
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.67
rrl 1475751 n.2094C>G non_coding_transcript_exon_variant 1.0
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 1.0
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 1.0
rrl 1475777 n.2120A>C non_coding_transcript_exon_variant 1.0
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 1.0
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 1.0
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 1.0
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.5
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.5
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.5
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rrl 1476413 n.2756A>G non_coding_transcript_exon_variant 0.29
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rpsA 1833931 c.390C>G synonymous_variant 0.67
rpsA 1833934 c.393C>T synonymous_variant 0.67
rpsA 1833955 c.414G>C synonymous_variant 0.75
rpsA 1833959 p.Leu140Val missense_variant 0.75
rpsA 1833970 c.429G>C synonymous_variant 0.75
rpsA 1833976 c.435C>T synonymous_variant 0.75
rpsA 1833979 c.438T>C synonymous_variant 0.75
rpsA 1833991 c.450C>A synonymous_variant 0.75
rpsA 1833997 c.456G>C synonymous_variant 0.67
rpsA 1833998 p.Val153Ile missense_variant 0.67
rpsA 1834004 p.Met155Leu missense_variant 0.67
rpsA 1834012 c.471G>C synonymous_variant 0.67
rpsA 1834015 c.474G>C synonymous_variant 1.0
rpsA 1834040 p.Lys167Gln missense_variant 1.0
rpsA 1834046 p.Ile169Leu missense_variant 1.0
rpsA 1834061 p.Ile174Leu missense_variant 1.0
rpsA 1834069 c.528G>C synonymous_variant 1.0
rpsA 1834093 c.552G>C synonymous_variant 0.67
rpsA 1834099 c.558C>G synonymous_variant 0.67
rpsA 1834102 c.561T>C synonymous_variant 0.67
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102514 p.Gly177Trp missense_variant 0.5
katG 2155643 p.Lys157Gln missense_variant 0.75
katG 2155674 c.438G>C synonymous_variant 0.86
katG 2155689 c.421_423delTTGinsCTC synonymous_variant 0.75
katG 2155695 p.Ala139Val missense_variant 0.75
katG 2155704 c.408C>G synonymous_variant 0.75
katG 2155716 c.396T>G synonymous_variant 0.75
katG 2155728 c.384G>C synonymous_variant 0.75
katG 2155880 p.Arg78Trp missense_variant 0.67
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289368 c.-127G>T upstream_gene_variant 0.67
Rv2752c 3066009 c.183G>T synonymous_variant 1.0
thyA 3073923 p.Leu183Phe missense_variant 1.0
ald 3086742 c.-78A>C upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449336 p.Gly278Asp missense_variant 0.67
alr 3840580 p.Val281Phe missense_variant 0.67
rpoA 3877920 c.588G>C synonymous_variant 1.0
rpoA 3877929 p.Ile193Val missense_variant 0.67
rpoA 3877932 c.576G>C synonymous_variant 0.67
rpoA 3878680 c.-173C>T upstream_gene_variant 1.0
clpC1 4038755 c.1950G>C synonymous_variant 0.75
clpC1 4038764 c.1941C>G synonymous_variant 0.75
clpC1 4038773 c.1932T>C synonymous_variant 1.0
clpC1 4038776 p.Glu643Asp missense_variant 1.0
clpC1 4038794 p.Ser637Leu missense_variant 1.0
clpC1 4038801 p.Tyr635Phe missense_variant 1.0
clpC1 4038803 p.Ile634Val missense_variant 1.0
clpC1 4038806 p.Glu633Asp missense_variant 1.0
clpC1 4038809 p.Gln632Pro missense_variant 1.0
clpC1 4038838 c.1867C>T synonymous_variant 1.0
clpC1 4039979 c.726C>G synonymous_variant 1.0
clpC1 4039994 p.Glu237Asp missense_variant 1.0
clpC1 4040000 p.His235Lys missense_variant 1.0
clpC1 4040009 c.696C>G synonymous_variant 1.0
clpC1 4040018 c.687G>C synonymous_variant 1.0
clpC1 4040021 c.684A>C synonymous_variant 1.0
clpC1 4040024 c.681A>G synonymous_variant 1.0
clpC1 4040030 c.675C>G synonymous_variant 1.0
clpC1 4040033 c.672G>C synonymous_variant 1.0
clpC1 4040036 c.669C>G synonymous_variant 1.0
clpC1 4040042 c.663C>A synonymous_variant 1.0
clpC1 4040057 c.648C>T synonymous_variant 1.0
clpC1 4040063 c.642G>C synonymous_variant 1.0
clpC1 4040066 c.639G>C synonymous_variant 0.88
clpC1 4040069 c.636G>C synonymous_variant 0.88
clpC1 4040083 p.Thr208Ser missense_variant 0.57
clpC1 4040087 c.618G>C synonymous_variant 0.5
clpC1 4040090 c.615T>G synonymous_variant 0.5
clpC1 4040096 p.Val203Ile missense_variant 0.5
clpC1 4040105 c.600C>G synonymous_variant 0.44
clpC1 4040108 c.597G>C synonymous_variant 0.44
clpC1 4040129 c.576C>G synonymous_variant 0.4
clpC1 4040618 c.87C>T synonymous_variant 1.0
clpC1 4040643 p.Arg21Lys missense_variant 0.5
clpC1 4040645 c.60C>G synonymous_variant 0.5
clpC1 4040657 c.48T>C synonymous_variant 0.5
embC 4240183 c.321A>G synonymous_variant 0.33
embC 4240204 c.342T>C synonymous_variant 0.33
embC 4240210 c.348C>G synonymous_variant 0.33
embC 4240216 c.354T>C synonymous_variant 0.33
embC 4240228 c.367_370delCTGC frameshift_variant 0.33
embC 4240234 p.Gln124His missense_variant 0.33
embC 4240236 c.374_375insTGCC frameshift_variant 0.4
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245556 c.2327delG frameshift_variant 0.5
ubiA 4269919 c.-86T>C upstream_gene_variant 1.0