TB-Profiler result

Run: ERR9285816
Summary

Run ID: ERR9285816

Sample name:

Date: 02-04-2023 11:40:57

Number of reads: 3768696

Percentage reads mapped: 58.98

Strain: lineage4.3.3

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3 Euro-American (LAM) mainly-LAM None 1.0
lineage4.3.3 Euro-American (LAM) LAM;T RD115 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 575909 p.Leu188Val missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.19
rpoC 764995 c.1626C>G synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.16
rrs 1472117 n.272A>T non_coding_transcript_exon_variant 0.18
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.18
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.18
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.19
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.2
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.2
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.2
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.23
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.21
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.21
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.21
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.21
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.21
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.18
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.17
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.16
rrs 1472518 n.673G>C non_coding_transcript_exon_variant 0.13
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.26
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.26
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.25
rrs 1472544 n.699C>G non_coding_transcript_exon_variant 0.25
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.25
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.27
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.26
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.26
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.26
rrs 1472574 n.729T>C non_coding_transcript_exon_variant 0.26
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.25
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.25
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.26
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.3
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.41
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.38
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.37
rrs 1472669 n.824_825insTAG non_coding_transcript_exon_variant 0.28
rrs 1472677 n.832C>G non_coding_transcript_exon_variant 0.27
rrs 1472678 n.833T>A non_coding_transcript_exon_variant 0.27
rrs 1472679 n.834_835insAC non_coding_transcript_exon_variant 0.28
rrs 1472684 n.841_846delGATCCG non_coding_transcript_exon_variant 0.28
rrs 1472697 n.852T>A non_coding_transcript_exon_variant 0.27
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.27
rrs 1472705 n.860G>A non_coding_transcript_exon_variant 0.26
rrs 1472708 n.863T>G non_coding_transcript_exon_variant 0.26
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.26
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.26
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.26
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.25
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.25
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.22
rrs 1472958 n.1114delT non_coding_transcript_exon_variant 0.38
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.13
rrs 1472975 n.1130T>A non_coding_transcript_exon_variant 0.37
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.37
rrs 1472983 n.1138A>C non_coding_transcript_exon_variant 0.38
rrs 1472986 n.1142delG non_coding_transcript_exon_variant 0.39
rrs 1472990 n.1146delG non_coding_transcript_exon_variant 0.38
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.42
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.43
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.44
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.43
rrs 1473020 n.1175T>C non_coding_transcript_exon_variant 0.44
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.45
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.4
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.32
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.29
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.18
rrs 1473070 n.1225G>A non_coding_transcript_exon_variant 0.14
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.12
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.11
rrl 1474830 n.1173A>C non_coding_transcript_exon_variant 0.1
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.1
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.11
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.1
rrl 1475696 n.2039T>C non_coding_transcript_exon_variant 0.13
rrl 1475703 n.2046A>G non_coding_transcript_exon_variant 0.17
rrl 1475707 n.2050T>A non_coding_transcript_exon_variant 0.2
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.24
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.27
rrl 1475759 n.2102C>G non_coding_transcript_exon_variant 0.25
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.26
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.26
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.24
rrl 1475782 n.2125T>C non_coding_transcript_exon_variant 0.24
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 0.24
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.24
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.24
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.27
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.28
rrl 1475843 n.2186G>A non_coding_transcript_exon_variant 0.21
rrl 1475849 n.2192G>A non_coding_transcript_exon_variant 0.18
rrl 1475853 n.2196C>T non_coding_transcript_exon_variant 0.12
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.13
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.13
rrl 1476229 n.2572C>A non_coding_transcript_exon_variant 0.12
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 0.28
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.33
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.37
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.39
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.36
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.35
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.36
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.35
rrl 1476297 n.2640C>A non_coding_transcript_exon_variant 0.35
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.35
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.35
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.35
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.36
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.45
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 0.49
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.55
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.56
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.57
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.55
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.54
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.48
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.47
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.47
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.46
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.42
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518919 p.Gly269Ser missense_variant 1.0
eis 2714504 p.His277Tyr missense_variant 1.0
thyA 3073868 p.Thr202Ala missense_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.48
whiB6 4338367 p.Leu52Gln missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0