TB-Profiler result

Run: SRR6964650
Summary

Run ID: SRR6964650

Sample name:

Date: 04-04-2023 18:20:31

Number of reads: 1128377

Percentage reads mapped: 96.52

Strain: lineage3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 766582 c.3213C>A synonymous_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304212 p.Val428Ile missense_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.24
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.24
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.24
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.24
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.25
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.28
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.22
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.11
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.1
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.12
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.17
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.17
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.19
rrs 1473226 n.1381C>G non_coding_transcript_exon_variant 0.21
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.11
rrl 1474166 n.509G>T non_coding_transcript_exon_variant 0.18
rrl 1474167 n.510T>C non_coding_transcript_exon_variant 0.18
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.3
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.3
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.27
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 0.21
rrl 1474218 n.561T>G non_coding_transcript_exon_variant 0.1
rrl 1474488 n.831G>A non_coding_transcript_exon_variant 0.19
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.19
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.19
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.2
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.2
rrl 1474516 n.859C>T non_coding_transcript_exon_variant 0.2
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.19
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.19
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.18
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.19
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.19
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.24
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.27
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.12
rrl 1476374 n.2717T>G non_coding_transcript_exon_variant 0.11
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.12
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.23
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.25
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.16
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ahpC 2726129 c.-64G>A upstream_gene_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
alr 3841473 c.-53G>A upstream_gene_variant 1.0
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245197 p.Ile655Met missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0