TB-Profiler result

Run: ERR4769512
Summary

Run ID: ERR4769512

Sample name:

Date: 01-04-2023 06:43:10

Number of reads: 9785

Percentage reads mapped: 0.42

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 761036 c.1230G>C synonymous_variant 0.67
rpoB 761037 c.1231T>C synonymous_variant 0.67
rpoB 761051 c.1245G>C synonymous_variant 0.67
rpoB 761054 c.1248G>C synonymous_variant 0.67
rpoB 761057 c.1251G>C synonymous_variant 0.67
rpoB 761060 c.1254C>G synonymous_variant 0.67
rpoB 761084 c.1278C>A synonymous_variant 0.67
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.67
rpoB 761096 c.1290G>C synonymous_variant 0.67
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.67
rpoB 761102 c.1296A>G synonymous_variant 0.67
rpoB 761126 c.1320G>C synonymous_variant 0.67
rpoB 761133 c.1327T>C synonymous_variant 0.5
rpoC 762452 c.-918G>C upstream_gene_variant 1.0
rpoC 762455 c.-915C>T upstream_gene_variant 1.0
rpoC 762467 c.-903C>T upstream_gene_variant 1.0
rpoB 762489 p.Val895Thr missense_variant 1.0
rpoC 762497 c.-873C>T upstream_gene_variant 1.0
rpoB 762507 p.Leu901Met missense_variant 1.0
rpoB 762510 p.Ala902Pro missense_variant 1.0
rpoC 762521 c.-849C>G upstream_gene_variant 1.0
rpoC 762548 c.-822C>T upstream_gene_variant 1.0
rpoC 762551 c.-819C>T upstream_gene_variant 1.0
rpoC 762560 c.-810A>T upstream_gene_variant 1.0
rpoC 762563 c.-807G>T upstream_gene_variant 1.0
rpoC 762569 c.-801C>T upstream_gene_variant 1.0
rpoC 762575 c.-795C>G upstream_gene_variant 1.0
rpoC 764344 c.975C>G synonymous_variant 1.0
rpoC 764353 c.984G>C synonymous_variant 1.0
rpoC 764365 c.996C>T synonymous_variant 1.0
rpoC 764371 c.1002G>C synonymous_variant 1.0
rrs 1472085 n.240C>G non_coding_transcript_exon_variant 1.0
rrs 1472086 n.241T>C non_coding_transcript_exon_variant 1.0
rrs 1472089 n.244C>T non_coding_transcript_exon_variant 1.0
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 1.0
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 1.0
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 1.0
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 1.0
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 1.0
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 1.0
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 1.0
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 1.0
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 1.0
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 1.0
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 1.0
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 1.0
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472253 n.408G>T non_coding_transcript_exon_variant 1.0
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 1.0
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 1.0
rrs 1472282 n.437T>G non_coding_transcript_exon_variant 1.0
rrs 1472338 n.493A>C non_coding_transcript_exon_variant 1.0
rrs 1472339 n.494C>A non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472518 n.673G>A non_coding_transcript_exon_variant 1.0
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 1.0
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 1.0
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 1.0
rrs 1472544 n.699C>T non_coding_transcript_exon_variant 1.0
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 1.0
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 1.0
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 1.0
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 1.0
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 1.0
rrs 1472579 n.734G>A non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 1.0
rrs 1472582 n.737G>A non_coding_transcript_exon_variant 1.0
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 1.0
rrs 1472599 n.754G>A non_coding_transcript_exon_variant 1.0
rrs 1472600 n.755C>T non_coding_transcript_exon_variant 1.0
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 1.0
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.98
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.98
rrs 1472659 n.814G>A non_coding_transcript_exon_variant 0.98
rrs 1472687 n.842_843insCC non_coding_transcript_exon_variant 0.97
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.97
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.97
rrs 1472705 n.860G>A non_coding_transcript_exon_variant 0.97
rrs 1472708 n.863T>A non_coding_transcript_exon_variant 0.97
rrs 1472715 n.870C>T non_coding_transcript_exon_variant 0.97
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.97
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.97
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.97
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.97
rrs 1472779 n.934G>A non_coding_transcript_exon_variant 1.0
rrs 1472956 n.1111T>G non_coding_transcript_exon_variant 0.92
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 1.0
rrs 1472958 n.1113A>T non_coding_transcript_exon_variant 0.92
rrs 1472959 n.1114T>A non_coding_transcript_exon_variant 0.92
rrs 1472965 n.1120C>T non_coding_transcript_exon_variant 0.92
rrs 1472967 n.1122G>C non_coding_transcript_exon_variant 0.92
rrs 1472969 n.1125_1126delCG non_coding_transcript_exon_variant 1.0
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.92
rrs 1472975 n.1130T>A non_coding_transcript_exon_variant 0.92
rrs 1472977 n.1132G>T non_coding_transcript_exon_variant 0.92
rrs 1472980 n.1135G>A non_coding_transcript_exon_variant 0.92
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.92
rrs 1472987 n.1142G>T non_coding_transcript_exon_variant 0.92
rrs 1472988 n.1143T>A non_coding_transcript_exon_variant 0.92
rrs 1472990 n.1145A>C non_coding_transcript_exon_variant 0.92
rrs 1473001 n.1156G>C non_coding_transcript_exon_variant 0.96
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.93
rrs 1473009 n.1164T>G non_coding_transcript_exon_variant 0.93
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.94
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.94
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.88
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 0.5
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 0.5
rrs 1473255 n.1410A>G non_coding_transcript_exon_variant 0.5
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.5
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.5
rrs 1473265 n.1420C>T non_coding_transcript_exon_variant 0.5
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 1.0
rrs 1473311 n.1466G>A non_coding_transcript_exon_variant 0.67
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.67
rrs 1473317 n.1472G>A non_coding_transcript_exon_variant 0.67
rrs 1473327 n.1482A>G non_coding_transcript_exon_variant 0.75
rrs 1473328 n.1483C>T non_coding_transcript_exon_variant 0.75
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 1.0
rrl 1473757 n.100T>G non_coding_transcript_exon_variant 1.0
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 1.0
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 1.0
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 1.0
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 1.0
rrl 1473833 n.176_177insT non_coding_transcript_exon_variant 1.0
rrl 1473844 n.187C>T non_coding_transcript_exon_variant 1.0
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.94
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.94
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.89
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.94
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.94
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 1.0
rrl 1475775 n.2118G>C non_coding_transcript_exon_variant 1.0
rrl 1475776 n.2119G>A non_coding_transcript_exon_variant 0.94
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.95
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.89
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.95
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.95
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.95
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.95
rrl 1475843 n.2186G>A non_coding_transcript_exon_variant 0.95
rrl 1475853 n.2196C>T non_coding_transcript_exon_variant 0.93
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 1.0
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 1.0
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0
rrl 1476099 n.2442A>G non_coding_transcript_exon_variant 1.0
rrl 1476103 n.2446C>A non_coding_transcript_exon_variant 1.0
rrl 1476105 n.2450delA non_coding_transcript_exon_variant 1.0
rrl 1476110 n.2453G>T non_coding_transcript_exon_variant 1.0
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 1.0
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 1.0
rrl 1476300 n.2643G>A non_coding_transcript_exon_variant 1.0
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 1.0
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.6
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.95
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.96
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.98
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.97
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.99
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.99
rrl 1476425 n.2768G>A non_coding_transcript_exon_variant 0.99
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.99
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.99
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.99
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.99
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.99
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 1.0
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 1.0
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.99
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.98
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.99
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.99
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.99
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.99
rrl 1476572 n.2915G>T non_coding_transcript_exon_variant 0.99
rrl 1476595 n.2938C>A non_coding_transcript_exon_variant 0.98
rrl 1476602 n.2945G>T non_coding_transcript_exon_variant 0.97
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 1.0
rrl 1476614 n.2957A>G non_coding_transcript_exon_variant 1.0
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 1.0
rrl 1476621 n.2964C>T non_coding_transcript_exon_variant 0.83
rrl 1476625 n.2968C>A non_coding_transcript_exon_variant 0.75
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 1.0
rrl 1476637 n.2980C>A non_coding_transcript_exon_variant 0.75
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 1.0
rpsA 1834249 c.708T>C synonymous_variant 1.0
rpsA 1834663 c.1122C>T synonymous_variant 1.0
rpsA 1834667 p.Ala376Ser missense_variant 1.0
rpsA 1834678 c.1137C>T synonymous_variant 1.0
rpsA 1834690 c.1149T>C synonymous_variant 1.0
rpsA 1834733 p.Ala398Pro missense_variant 1.0
rpsA 1834738 c.1197A>G synonymous_variant 1.0
rpsA 1834753 c.1212T>C synonymous_variant 1.0
rpsA 1834759 c.1218A>C synonymous_variant 1.0
rpsA 1834765 p.Glu408Asp missense_variant 1.0
rpsA 1834776 p.Ala412Glu missense_variant 1.0
rpsA 1834780 c.1239A>G synonymous_variant 1.0
rpsA 1834788 p.Ala416Gly missense_variant 1.0
rpsA 1834792 c.1251G>C synonymous_variant 1.0
clpC1 4040291 c.414G>C synonymous_variant 1.0
clpC1 4040303 c.402G>C synonymous_variant 1.0
clpC1 4040310 p.Thr132Asn missense_variant 1.0
clpC1 4040312 c.393G>C synonymous_variant 1.0
clpC1 4040315 p.Glu130Asp missense_variant 1.0
clpC1 4040324 c.381G>C synonymous_variant 1.0
clpC1 4040345 c.360C>G synonymous_variant 1.0
clpC1 4040348 c.357G>C synonymous_variant 1.0
clpC1 4040354 c.351A>G synonymous_variant 1.0
clpC1 4040357 c.348T>C synonymous_variant 1.0
clpC1 4040363 c.342A>C synonymous_variant 1.0
clpC1 4040369 c.336C>G synonymous_variant 1.0
clpC1 4040375 c.330G>C synonymous_variant 1.0
clpC1 4040380 c.325T>C synonymous_variant 1.0
clpC1 4040387 c.318A>G synonymous_variant 1.0
clpC1 4040393 c.312G>C synonymous_variant 1.0