TB-Profiler result

Run: SRR8692905
Summary

Run ID: SRR8692905

Sample name:

Date: 13-08-2023 20:12:59

Number of reads: NA

Percentage reads mapped: NA

Strain:

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rplC 801268 p.Cys154Arg missense_variant 0.78 linezolid
katG 2155501 p.Trp204* stop_gained 0.22 isoniazid
ddn 3987085 p.Gly81Asp missense_variant 0.14 delamanid
ethA 4326426 c.1047delT frameshift_variant 0.2 ethionamide, ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5064 c.-176C>A upstream_gene_variant 0.2
gyrB 5867 p.Asp210Tyr missense_variant 0.25
gyrB 6002 p.Gly255Cys missense_variant 0.17
gyrB 6067 c.828G>T synonymous_variant 0.2
gyrB 6082 p.Lys281Asn missense_variant 0.22
gyrB 6178 c.939C>T synonymous_variant 0.22
gyrB 6196 c.957C>G synonymous_variant 0.22
gyrB 6200 c.961_963delCGCinsAGG synonymous_variant 0.22
gyrB 6203 p.Ser322Ala missense_variant 0.22
gyrB 6214 c.975G>C synonymous_variant 0.2
gyrB 6215 p.Ser326Thr missense_variant 0.2
gyrB 6223 c.984G>C synonymous_variant 0.23
gyrB 6242 p.Arg335Lys missense_variant 0.23
gyrB 6250 c.1011A>G synonymous_variant 0.23
gyrB 6253 c.1014G>C synonymous_variant 0.23
gyrB 6265 c.1026C>T synonymous_variant 0.17
gyrB 6268 c.1029C>G synonymous_variant 0.18
gyrB 6280 c.1041T>C synonymous_variant 0.18
gyrB 6286 c.1047T>C synonymous_variant 0.17
gyrB 6292 c.1053G>T synonymous_variant 0.18
gyrB 6295 c.1056A>G synonymous_variant 0.18
gyrB 6298 c.1059C>T synonymous_variant 0.2
gyrA 6307 c.-995T>G upstream_gene_variant 0.27
gyrA 6310 c.-992G>C upstream_gene_variant 0.18
gyrB 6324 c.1086dupC frameshift_variant 0.18
gyrB 6328 c.1090delG frameshift_variant 0.18
gyrA 6331 c.-971A>G upstream_gene_variant 0.18
gyrA 6550 c.-752A>T upstream_gene_variant 0.17
gyrA 6551 c.-751T>C upstream_gene_variant 0.17
gyrA 6565 c.-737G>C upstream_gene_variant 0.17
gyrA 6571 c.-731T>C upstream_gene_variant 0.17
gyrA 6577 c.-725T>C upstream_gene_variant 0.23
gyrA 6583 c.-719G>C upstream_gene_variant 0.2
gyrA 6586 c.-716T>C upstream_gene_variant 0.2
gyrB 6590 p.Arg451Ser missense_variant 0.2
gyrA 6610 c.-692C>G upstream_gene_variant 0.12
gyrA 6613 c.-689A>G upstream_gene_variant 0.12
gyrA 6619 c.-683T>C upstream_gene_variant 0.12
gyrA 6637 c.-665T>G upstream_gene_variant 0.12
gyrA 6649 c.-653T>G upstream_gene_variant 0.12
gyrA 6655 c.-647T>C upstream_gene_variant 0.12
gyrA 6673 c.-629A>C upstream_gene_variant 0.17
gyrA 6676 c.-626T>G upstream_gene_variant 0.17
gyrB 6723 p.Arg495Leu missense_variant 0.5
gyrA 6832 c.-470C>A upstream_gene_variant 0.4
gyrA 6943 c.-359G>T upstream_gene_variant 0.33
gyrA 7165 c.-137C>A upstream_gene_variant 0.17
gyrB 7167 p.Ala643Asp missense_variant 0.25
gyrA 7362 p.Glu21Gln missense_variant 0.69
gyrA 7391 c.90C>T synonymous_variant 0.2
gyrA 7394 c.93T>C synonymous_variant 0.2
gyrA 7397 c.96G>C synonymous_variant 0.22
gyrA 7406 c.105G>C synonymous_variant 0.25
gyrA 7412 c.111C>G synonymous_variant 0.25
gyrA 7421 c.120G>C synonymous_variant 0.25
gyrA 7424 c.123G>T synonymous_variant 0.23
gyrA 7427 c.126G>C synonymous_variant 0.3
gyrA 7433 c.132G>C synonymous_variant 0.25
gyrA 7442 c.141G>C synonymous_variant 0.27
gyrA 7451 c.150C>G synonymous_variant 0.25
gyrA 7457 c.156T>C synonymous_variant 0.23
gyrA 7475 c.174A>C synonymous_variant 0.21
gyrA 7480 p.Phe60Tyr missense_variant 0.23
gyrA 7484 c.183T>C synonymous_variant 0.25
gyrA 7487 c.186C>G synonymous_variant 0.23
gyrA 7502 c.201C>T synonymous_variant 0.23
gyrA 7506 p.Ser69Gly missense_variant 0.23
gyrA 7520 c.219G>C synonymous_variant 0.18
gyrA 7585 p.Ser95Thr missense_variant 0.25
gyrA 7658 c.357A>G synonymous_variant 0.14
gyrA 7661 c.360C>T synonymous_variant 0.14
gyrA 7664 c.363T>C synonymous_variant 0.14
gyrA 7670 c.369A>G synonymous_variant 0.15
gyrA 7676 c.375G>C synonymous_variant 0.15
gyrA 7679 c.378G>C synonymous_variant 0.15
gyrA 7683 c.382_384delAGGinsCGC synonymous_variant 0.17
gyrA 7694 c.393A>G synonymous_variant 0.23
gyrA 7700 c.399G>T synonymous_variant 0.23
gyrA 7706 c.405C>T synonymous_variant 0.21
gyrA 7709 c.408G>A synonymous_variant 0.23
gyrA 7710 c.409T>C synonymous_variant 0.23
gyrA 7715 c.414G>C synonymous_variant 0.23
gyrA 7728 c.427_429delAGGinsCGT synonymous_variant 0.21
gyrA 7752 p.Asp151Asn missense_variant 0.33
gyrA 7763 c.462T>C synonymous_variant 0.38
gyrA 7769 c.468C>T synonymous_variant 0.43
gyrA 7775 c.474C>G synonymous_variant 0.33
gyrA 7778 c.477G>C synonymous_variant 0.33
gyrA 7784 c.483A>G synonymous_variant 0.33
gyrA 8021 c.720C>A synonymous_variant 0.33
gyrA 8486 c.1185T>C synonymous_variant 0.12
gyrA 8489 c.1188A>G synonymous_variant 0.12
gyrA 8504 c.1203G>C synonymous_variant 0.15
gyrA 8516 c.1215T>C synonymous_variant 0.14
gyrA 8520 c.1219C>T synonymous_variant 0.15
gyrA 8531 c.1230G>C synonymous_variant 0.15
gyrA 8536 p.Glu412Ala missense_variant 0.12
gyrA 8542 p.Val414Ala missense_variant 0.12
gyrA 8547 p.Ile416Val missense_variant 0.12
gyrA 8555 c.1254G>C synonymous_variant 0.13
gyrA 8557 p.Ala419Gly missense_variant 0.12
gyrA 8561 c.1260A>C synonymous_variant 0.12
gyrA 8567 p.Ile422Met missense_variant 0.12
gyrA 8603 c.1302A>C synonymous_variant 0.15
gyrA 8609 c.1308G>C synonymous_variant 0.14
gyrA 8649 p.Arg450Ser missense_variant 0.15
gyrA 8990 c.1689C>G synonymous_variant 0.12
gyrA 9050 p.Asp583Glu missense_variant 0.14
gyrA 9051 c.1750T>C synonymous_variant 0.14
gyrA 9056 c.1755C>G synonymous_variant 0.13
gyrA 9072 p.Ala591Ser missense_variant 0.17
gyrA 9086 c.1785C>T synonymous_variant 0.18
gyrA 9128 c.1827C>A synonymous_variant 0.22
gyrA 9218 c.1917C>T synonymous_variant 0.15
gyrA 9304 p.Gly668Asp missense_variant 0.27
gyrA 9596 c.2295G>C synonymous_variant 0.2
fgd1 490602 c.-181C>T upstream_gene_variant 0.2
fgd1 490906 p.Gln42Lys missense_variant 0.18
fgd1 490941 p.Phe53Leu missense_variant 0.18
fgd1 491002 p.Val74Leu missense_variant 0.13
fgd1 491491 p.Pro237Thr missense_variant 0.15
fgd1 491496 c.714C>T synonymous_variant 0.15
fgd1 491503 p.Leu241Ala missense_variant 0.17
fgd1 491508 c.726A>G synonymous_variant 0.17
fgd1 491509 c.727T>C synonymous_variant 0.17
fgd1 491512 p.Asn244Glu missense_variant 0.17
fgd1 491526 c.744T>C synonymous_variant 0.15
fgd1 491542 c.760T>C synonymous_variant 0.13
fgd1 491547 c.765A>C synonymous_variant 0.13
fgd1 491550 c.768T>C synonymous_variant 0.14
fgd1 491563 p.Ser261Cys missense_variant 0.13
fgd1 491601 c.819T>C synonymous_variant 0.12
fgd1 491610 c.828A>C synonymous_variant 0.13
mshA 575316 c.-32C>A upstream_gene_variant 0.13
mshA 575478 p.Pro44Leu missense_variant 0.2
mshA 575596 c.249C>A synonymous_variant 0.25
ccsA 619763 c.-128C>A upstream_gene_variant 0.18
ccsA 620374 p.Pro162Thr missense_variant 0.29
ccsA 620583 c.693G>T synonymous_variant 0.25
ccsA 620588 p.Thr233Met missense_variant 0.22
rpoB 760198 p.Ala131Asp missense_variant 0.12
rpoB 760361 c.555T>C synonymous_variant 0.17
rpoB 760368 p.Ser188Ala missense_variant 0.22
rpoB 760376 p.Asp190Glu missense_variant 0.25
rpoB 760380 p.Thr192Asp missense_variant 0.25
rpoB 760400 c.594G>C synonymous_variant 0.22
rpoB 760407 p.Ser201Gly missense_variant 0.22
rpoB 760415 c.609C>T synonymous_variant 0.33
rpoB 760424 c.618C>G synonymous_variant 0.25
rpoB 760430 c.624T>C synonymous_variant 0.25
rpoB 760457 c.651C>T synonymous_variant 0.38
rpoB 760475 c.669A>G synonymous_variant 0.3
rpoB 760481 c.675G>T synonymous_variant 0.3
rpoB 760484 c.678A>G synonymous_variant 0.3
rpoB 760502 c.696C>G synonymous_variant 0.25
rpoB 760508 c.702G>C synonymous_variant 0.18
rpoB 760511 c.705G>C synonymous_variant 0.18
rpoB 760522 p.Ser239Asn missense_variant 0.18
rpoB 760532 c.726T>C synonymous_variant 0.18
rpoB 760535 c.729C>G synonymous_variant 0.18
rpoB 760541 c.735G>C synonymous_variant 0.25
rpoB 760547 c.741G>C synonymous_variant 0.25
rpoB 760561 c.757_758delCG frameshift_variant 0.2
rpoB 760567 p.Ser254Trp missense_variant 0.17
rpoB 760568 c.762_763insGC frameshift_variant 0.18
rpoB 760591 p.Val262Ala missense_variant 0.15
rpoB 760796 c.990A>G synonymous_variant 0.19
rpoB 760805 c.999G>C synonymous_variant 0.18
rpoB 760808 c.1002C>G synonymous_variant 0.18
rpoB 760811 c.1005C>G synonymous_variant 0.18
rpoB 760817 c.1011A>G synonymous_variant 0.18
rpoB 760820 c.1014T>C synonymous_variant 0.18
rpoB 760826 c.1020C>G synonymous_variant 0.19
rpoB 760830 c.1024T>C synonymous_variant 0.22
rpoB 760841 c.1035T>C synonymous_variant 0.28
rpoB 760858 p.Val351Ala missense_variant 0.28
rpoB 760862 c.1056G>C synonymous_variant 0.28
rpoB 760877 c.1071G>T synonymous_variant 0.31
rpoB 760880 c.1074G>C synonymous_variant 0.31
rpoB 760883 c.1077G>C synonymous_variant 0.31
rpoB 760886 c.1080A>G synonymous_variant 0.31
rpoB 760887 p.Thr361Val missense_variant 0.31
rpoB 760910 c.1104C>T synonymous_variant 0.33
rpoB 760919 c.1113C>T synonymous_variant 0.33
rpoB 760925 c.1119T>C synonymous_variant 0.31
rpoB 760928 c.1122G>C synonymous_variant 0.31
rpoB 760946 c.1140A>G synonymous_variant 0.17
rpoB 760965 p.Met387Leu missense_variant 0.17
rpoB 760970 c.1164G>C synonymous_variant 0.17
rpoB 760973 c.1167G>C synonymous_variant 0.17
rpoB 760977 p.Glu391* stop_gained 0.17
rpoB 760981 p.Arg392Leu missense_variant 0.2
rpoB 760989 c.1183C>A synonymous_variant 0.22
rpoB 760992 p.Glu396* stop_gained 0.25
rpoB 761132 c.1326G>T synonymous_variant 0.5
rpoB 761133 c.1327T>C synonymous_variant 0.5
rpoB 761147 c.1341C>T synonymous_variant 0.44
rpoB 761150 c.1344A>T synonymous_variant 0.4
rpoB 761165 c.1359G>C synonymous_variant 0.4
rpoB 761180 c.1374A>C synonymous_variant 0.4
rpoB 761189 c.1383T>C synonymous_variant 0.4
rpoB 761195 c.1389G>C synonymous_variant 0.4
rpoB 761198 c.1392G>T synonymous_variant 0.4
rpoB 761217 p.Pro471Ser missense_variant 0.33
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 0.33
rpoB 761249 c.1443A>G synonymous_variant 0.33
rpoB 761261 c.1455G>C synonymous_variant 0.29
rpoB 761300 c.1494G>C synonymous_variant 0.4
rpoB 761318 c.1512G>C synonymous_variant 0.4
rpoB 761327 c.1521A>G synonymous_variant 0.33
rpoB 761345 c.1539G>C synonymous_variant 0.29
rpoB 761346 p.Val514Ile missense_variant 0.29
rpoB 761355 p.Val517Gln missense_variant 0.29
rpoB 761360 c.1554T>C synonymous_variant 0.29
rpoB 761362 p.Ser519Thr missense_variant 0.29
rpoB 761367 p.Glu521Gln missense_variant 0.29
rpoB 761374 p.Val523Asp missense_variant 0.33
rpoB 761384 c.1578C>A synonymous_variant 0.33
rpoB 761403 p.His533Asn missense_variant 0.29
rpoB 761482 p.Ala559Val missense_variant 0.18
rpoB 761529 p.Val575Phe missense_variant 0.18
rpoB 762020 p.Glu738Asp missense_variant 0.13
rpoB 762053 c.2247T>C synonymous_variant 0.12
rpoB 762065 c.2259T>C synonymous_variant 0.17
rpoB 762083 c.2277T>C synonymous_variant 0.15
rpoB 762086 c.2280G>C synonymous_variant 0.15
rpoB 762101 c.2295C>G synonymous_variant 0.16
rpoB 762131 c.2325C>G synonymous_variant 0.12
rpoB 762137 c.2331C>T synonymous_variant 0.12
rpoB 762140 c.2334G>C synonymous_variant 0.12
rpoB 762143 c.2337T>C synonymous_variant 0.12
rpoB 762149 c.2343G>C synonymous_variant 0.12
rpoB 762156 p.Val784Ile missense_variant 0.17
rpoB 762167 c.2361T>C synonymous_variant 0.17
rpoB 762176 c.2370T>C synonymous_variant 0.17
rpoB 762185 c.2379G>C synonymous_variant 0.19
rpoB 762233 c.2427G>T synonymous_variant 0.15
rpoB 762955 p.Pro1050Gln missense_variant 0.22
rpoC 763031 c.-339T>C upstream_gene_variant 0.27
rpoC 763052 c.-318G>T upstream_gene_variant 0.2
rpoB 763244 p.Asp1146Glu missense_variant 0.22
rpoC 763411 c.42T>C synonymous_variant 0.15
rpoC 763414 c.45T>G synonymous_variant 0.15
rpoC 763423 p.Glu18Asp missense_variant 0.17
rpoC 763430 c.61_63delAGGinsCGC synonymous_variant 0.15
rpoC 763433 p.Gln22Asn missense_variant 0.15
rpoC 763443 p.Tyr25Phe missense_variant 0.2
rpoC 763456 c.87A>G synonymous_variant 0.21
rpoC 763468 c.99G>C synonymous_variant 0.21
rpoC 763486 c.117T>C synonymous_variant 0.19
rpoC 763495 c.126G>A synonymous_variant 0.19
rpoC 764017 c.648G>T synonymous_variant 0.25
rpoC 764096 p.Glu243* stop_gained 0.21
rpoC 764320 c.951C>T synonymous_variant 0.21
rpoC 764353 c.984G>T synonymous_variant 0.2
rpoC 764365 c.996C>T synonymous_variant 0.29
rpoC 764371 c.1002G>C synonymous_variant 0.15
rpoC 764377 c.1008C>G synonymous_variant 0.23
rpoC 764380 c.1011G>C synonymous_variant 0.23
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.25
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.25
rpoC 764410 c.1041G>C synonymous_variant 0.23
rpoC 764431 c.1062G>C synonymous_variant 0.27
rpoC 764434 c.1065A>G synonymous_variant 0.27
rpoC 764435 c.1066_1068delAGGinsCGA synonymous_variant 0.25
rpoC 764452 c.1083T>C synonymous_variant 0.24
rpoC 764458 c.1089G>C synonymous_variant 0.25
rpoC 764461 c.1092A>G synonymous_variant 0.2
rpoC 764485 c.1116G>C synonymous_variant 0.14
rpoC 764491 c.1122G>T synonymous_variant 0.14
rpoC 764497 c.1128A>G synonymous_variant 0.13
rpoC 764500 c.1131C>G synonymous_variant 0.13
rpoC 764521 c.1152T>C synonymous_variant 0.13
rpoC 764746 c.1377G>T synonymous_variant 0.17
rpoC 764752 c.1383G>C synonymous_variant 0.15
rpoC 764758 c.1389C>G synonymous_variant 0.17
rpoC 764764 c.1395T>C synonymous_variant 0.16
rpoC 764800 c.1431G>A synonymous_variant 0.14
rpoC 764803 c.1434C>T synonymous_variant 0.15
rpoC 764809 c.1440C>T synonymous_variant 0.19
rpoC 764815 c.1446A>G synonymous_variant 0.19
rpoC 764827 c.1458G>C synonymous_variant 0.2
rpoC 764858 c.1489T>C synonymous_variant 0.15
rpoC 764960 p.Ala531Ser missense_variant 0.29
rpoC 765800 p.Phe811Leu missense_variant 0.33
rpoC 765811 c.2442T>C synonymous_variant 0.38
rpoC 765814 c.2445A>C synonymous_variant 0.38
rpoC 765820 c.2451G>C synonymous_variant 0.38
rpoC 765823 c.2454C>G synonymous_variant 0.38
rpoC 765826 c.2457T>C synonymous_variant 0.44
rpoC 765835 c.2466C>T synonymous_variant 0.56
rpoC 765861 p.Phe831Tyr missense_variant 0.67
rpoC 765875 p.Val836Ile missense_variant 0.75
rpoC 765886 c.2517C>G synonymous_variant 0.75
rpoC 765892 c.2523T>C synonymous_variant 0.86
rpoC 765898 c.2529C>T synonymous_variant 0.86
rpoC 765934 c.2565C>T synonymous_variant 0.5
rpoC 765937 c.2568T>C synonymous_variant 0.33
rpoC 765940 c.2571A>T synonymous_variant 0.33
rpoC 765946 c.2577C>T synonymous_variant 0.27
rpoC 765947 c.2578T>C synonymous_variant 0.25
rpoC 765952 c.2583G>C synonymous_variant 0.27
rpoC 765962 c.2593T>C synonymous_variant 0.27
rpoC 765967 c.2598C>T synonymous_variant 0.27
rpoC 766618 c.3249G>T synonymous_variant 0.17
rpoC 766659 p.Arg1097Leu missense_variant 0.17
rpoC 766690 c.3321G>C synonymous_variant 0.14
rpoC 766702 c.3333G>C synonymous_variant 0.17
rpoC 766711 c.3342C>T synonymous_variant 0.15
rpoC 766712 p.Ser1115Ala missense_variant 0.15
rpoC 766720 c.3351C>T synonymous_variant 0.15
rpoC 766726 c.3357T>C synonymous_variant 0.13
rpoC 766750 c.3381C>G synonymous_variant 0.14
rpoC 766765 c.3396A>C synonymous_variant 0.15
rpoC 766771 c.3402G>C synonymous_variant 0.15
rpoC 766774 c.3405T>C synonymous_variant 0.14
rpoC 766775 c.3406_3408delCGCinsAGG synonymous_variant 0.14
rpoC 767035 c.3666G>C synonymous_variant 0.29
rpoC 767098 c.3729T>C synonymous_variant 0.25
rpoC 767104 c.3735C>G synonymous_variant 0.25
rpoC 767106 p.Asn1246Met missense_variant 0.25
rpoC 767119 c.3750A>G synonymous_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 0.5
mmpL5 775687 p.Leu932Ile missense_variant 0.2
mmpL5 775718 c.2763C>A synonymous_variant 0.2
mmpL5 775856 c.2625T>C synonymous_variant 0.2
mmpL5 775865 c.2616T>C synonymous_variant 0.2
mmpL5 775885 p.Ile866Leu missense_variant 0.25
mmpL5 775886 c.2595A>T synonymous_variant 0.18
mmpL5 775889 c.2592C>G synonymous_variant 0.14
mmpL5 775892 c.2589C>T synonymous_variant 0.14
mmpL5 775907 p.Leu858Met missense_variant 0.18
mmpL5 775915 p.Ala856Ser missense_variant 0.29
mmpL5 775916 c.2565T>C synonymous_variant 0.33
mmpL5 775921 p.Leu854Val missense_variant 0.14
mmpL5 775949 c.2532G>C synonymous_variant 0.19
mmpL5 775955 p.Ile842Val missense_variant 0.29
mmpL5 775961 c.2520C>G synonymous_variant 0.33
mmpL5 775972 p.Ala837Pro missense_variant 0.18
mmpL5 775975 c.2506T>C synonymous_variant 0.19
mmpL5 775981 p.Leu834Met missense_variant 0.33
mmpL5 775991 c.2490G>A synonymous_variant 0.24
mmpL5 775994 p.Ile829Met missense_variant 0.12
mmpL5 775997 c.2484T>C synonymous_variant 0.35
mmpL5 776000 p.Leu827Ile missense_variant 0.27
mmpL5 776009 c.2472A>G synonymous_variant 0.25
mmpL5 776036 c.2445G>C synonymous_variant 0.15
mmpL5 776564 c.1917C>A synonymous_variant 0.15
mmpL5 776576 c.1905C>A synonymous_variant 0.18
mmpL5 776805 p.Gly559Val missense_variant 0.22
mmpL5 777256 p.Pro409Ala missense_variant 0.13
mmpL5 778321 p.Glu54* stop_gained 0.2
mmpL5 778504 c.-24G>T upstream_gene_variant 0.29
mmpR5 779059 p.Gly24Cys missense_variant 0.14
mmpR5 779098 p.Gly37Cys missense_variant 0.22
mmpR5 779109 p.Leu40Phe missense_variant 0.25
mmpR5 779437 p.Val150Phe missense_variant 0.17
mmpS5 779567 c.-664_-662delGCGinsTCT upstream_gene_variant 0.17
rpsL 781381 c.-179C>A upstream_gene_variant 0.29
rpsL 781395 c.-165T>C upstream_gene_variant 0.43
rpsL 781623 p.Ala22Thr missense_variant 0.17
rpsL 781652 c.93T>C synonymous_variant 0.14
rpsL 781658 c.99A>G synonymous_variant 0.13
rpsL 781682 c.123T>C synonymous_variant 0.14
rpsL 781715 c.156T>C synonymous_variant 0.12
rpsL 781728 c.169T>C synonymous_variant 0.13
rpsL 781735 p.Ser59Thr missense_variant 0.13
rpsL 781737 p.Gln60Gly missense_variant 0.14
rpsL 781742 c.183C>T synonymous_variant 0.14
rpsL 781751 c.192G>C synonymous_variant 0.14
rpsL 781754 c.195G>C synonymous_variant 0.14
rpsL 781760 c.201T>C synonymous_variant 0.15
rpsL 781769 c.210G>A synonymous_variant 0.17
rpsL 781787 p.Glu76Asp missense_variant 0.13
rpsL 781829 c.270G>C synonymous_variant 0.13
rpsL 781832 c.273T>G synonymous_variant 0.13
rpsL 781916 c.357T>G synonymous_variant 0.15
rpsL 781929 p.Gly124Ser missense_variant 0.14
rpsL 781933 c.374G>A splice_region_variant&stop_retained_variant 0.15
rplC 800612 c.-197A>G upstream_gene_variant 0.36
rplC 800618 c.-191T>C upstream_gene_variant 0.33
rplC 800633 c.-176T>C upstream_gene_variant 0.5
rplC 800639 c.-170C>T upstream_gene_variant 0.5
rplC 800645 c.-164C>G upstream_gene_variant 0.62
rplC 800648 c.-161A>C upstream_gene_variant 0.62
rplC 800651 c.-158G>C upstream_gene_variant 0.62
rplC 800678 c.-131C>T upstream_gene_variant 0.27
rplC 800723 c.-86C>A upstream_gene_variant 0.18
rplC 800777 c.-32C>T upstream_gene_variant 0.17
rplC 800935 p.Glu43* stop_gained 0.18
rplC 801252 c.444G>A synonymous_variant 0.25
fbiC 1303064 p.Ala45Asp missense_variant 0.17
fbiC 1303178 p.Ala83Glu missense_variant 0.17
fbiC 1303350 p.Cys140* stop_gained 0.29
fbiC 1303518 p.Met196Ile missense_variant 0.17
fbiC 1303651 p.Arg241Trp missense_variant 0.25
fbiC 1303690 p.Pro254Thr missense_variant 0.17
fbiC 1303710 p.Leu260Phe missense_variant 0.25
fbiC 1305369 p.Glu813Asp missense_variant 0.18
Rv1258c 1406441 p.Leu300Phe missense_variant 0.25
Rv1258c 1406561 c.780G>T synonymous_variant 0.14
Rv1258c 1406659 p.Leu228Ile missense_variant 0.12
Rv1258c 1406686 p.Val219Ile missense_variant 0.54
Rv1258c 1406760 c.580_581insC frameshift_variant 0.2
Rv1258c 1407013 p.Ala110Ser missense_variant 0.4
Rv1258c 1407420 c.-80C>A upstream_gene_variant 0.2
embR 1417176 p.Ala58Ser missense_variant 0.17
embR 1417430 c.-83C>A upstream_gene_variant 0.2
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471866 n.21C>T non_coding_transcript_exon_variant 0.29
rrs 1471922 n.78delT non_coding_transcript_exon_variant 0.22
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.22
rrs 1471931 n.87delA non_coding_transcript_exon_variant 0.25
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.25
rrs 1471979 n.134T>C non_coding_transcript_exon_variant 0.2
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.36
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 0.3
rrs 1472023 n.178G>T non_coding_transcript_exon_variant 0.3
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 0.33
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.33
rrs 1472033 n.188A>C non_coding_transcript_exon_variant 0.33
rrs 1472035 n.190G>T non_coding_transcript_exon_variant 0.33
rrs 1472040 n.195T>G non_coding_transcript_exon_variant 0.36
rrs 1472043 n.198T>G non_coding_transcript_exon_variant 0.33
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.33
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.33
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.42
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.42
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.62
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.25
rrs 1472380 n.535G>C non_coding_transcript_exon_variant 0.29
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 0.46
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 0.4
rrs 1472463 n.618G>T non_coding_transcript_exon_variant 0.14
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.43
rrs 1472471 n.626G>T non_coding_transcript_exon_variant 0.15
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.5
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.69
rrs 1472826 n.981G>T non_coding_transcript_exon_variant 0.17
rrs 1472847 n.1002G>C non_coding_transcript_exon_variant 0.18
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.18
rrs 1472849 n.1004C>G non_coding_transcript_exon_variant 0.18
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.18
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.22
rrs 1472858 n.1013G>T non_coding_transcript_exon_variant 0.22
rrs 1472859 n.1014G>C non_coding_transcript_exon_variant 0.22
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.22
rrs 1473000 n.1155G>T non_coding_transcript_exon_variant 0.2
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.64
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.6
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.6
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.47
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.56
rrl 1473717 n.60G>A non_coding_transcript_exon_variant 0.29
rrl 1473731 n.74T>A non_coding_transcript_exon_variant 0.25
rrl 1473736 n.79C>T non_coding_transcript_exon_variant 0.22
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.4
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.42
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.42
rrl 1473779 n.122G>T non_coding_transcript_exon_variant 0.25
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.54
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.58
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.64
rrl 1473816 n.159C>G non_coding_transcript_exon_variant 0.64
rrl 1473828 n.171G>C non_coding_transcript_exon_variant 0.64
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 0.64
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 0.64
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 0.64
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.56
rrl 1473887 n.230T>A non_coding_transcript_exon_variant 0.44
rrl 1473888 n.231T>A non_coding_transcript_exon_variant 0.44
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.33
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.33
rrl 1474116 n.459G>T non_coding_transcript_exon_variant 0.5
rrl 1474135 n.478G>A non_coding_transcript_exon_variant 0.25
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.33
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.33
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.33
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.33
rrl 1474183 n.526T>C non_coding_transcript_exon_variant 0.33
rrl 1474185 n.528G>A non_coding_transcript_exon_variant 0.33
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.5
rrl 1474299 n.642C>A non_coding_transcript_exon_variant 0.67
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 0.22
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.27
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.27
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.25
rrl 1474498 n.841G>A non_coding_transcript_exon_variant 0.23
rrl 1474505 n.848C>T non_coding_transcript_exon_variant 0.25
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.27
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.27
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.27
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.42
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.45
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.47
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.47
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.47
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 0.53
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.56
rrl 1474753 n.1096A>G non_coding_transcript_exon_variant 0.54
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.57
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.57
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.64
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.69
rrl 1475108 n.1451C>G non_coding_transcript_exon_variant 0.67
rrl 1475343 n.1686A>G non_coding_transcript_exon_variant 0.62
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.5
rrl 1475358 n.1701T>C non_coding_transcript_exon_variant 0.5
rrl 1475363 n.1706C>T non_coding_transcript_exon_variant 0.55
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.55
rrl 1475374 n.1717G>T non_coding_transcript_exon_variant 0.18
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 0.5
rrl 1475381 n.1724G>T non_coding_transcript_exon_variant 0.5
rrl 1475382 n.1725A>C non_coding_transcript_exon_variant 0.5
rrl 1475395 n.1738T>G non_coding_transcript_exon_variant 0.56
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 0.56
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 0.56
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.59
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.5
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.55
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.62
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.65
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.58
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.58
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.55
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.52
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.52
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 0.44
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.25
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 0.53
rrl 1475759 n.2102C>T non_coding_transcript_exon_variant 0.53
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.62
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.62
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.62
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.57
rrl 1475775 n.2118G>A non_coding_transcript_exon_variant 0.57
rrl 1475819 n.2162C>A non_coding_transcript_exon_variant 0.17
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.54
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 0.5
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 0.5
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 0.46
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 0.46
rrl 1476034 n.2377C>G non_coding_transcript_exon_variant 0.46
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 0.46
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 0.55
rrl 1476045 n.2388G>T non_coding_transcript_exon_variant 0.55
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 0.55
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 0.55
rrl 1476056 n.2399G>A non_coding_transcript_exon_variant 0.55
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 0.27
rrl 1476095 n.2438C>T non_coding_transcript_exon_variant 0.3
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 0.27
rrl 1476105 n.2448G>A non_coding_transcript_exon_variant 0.27
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 0.27
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 0.27
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.33
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.33
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.5
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.5
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.53
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 0.73
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 0.73
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.67
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.64
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.67
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.67
rrl 1476370 n.2713C>A non_coding_transcript_exon_variant 0.14
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.71
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.69
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.55
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.38
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.38
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 0.25
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 0.18
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.2
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.18
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.18
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.18
rrl 1476711 n.3054G>A non_coding_transcript_exon_variant 0.2
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.2
rrl 1476719 n.3062C>T non_coding_transcript_exon_variant 0.2
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.2
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.18
rrl 1476731 n.3074G>A non_coding_transcript_exon_variant 0.15
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.14
rrl 1476741 n.3084G>T non_coding_transcript_exon_variant 0.15
rrl 1476743 n.3086A>C non_coding_transcript_exon_variant 0.13
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.12
rrl 1476758 n.3101G>T non_coding_transcript_exon_variant 0.15
rrl 1476770 n.3113T>C non_coding_transcript_exon_variant 0.14
rrl 1476771 n.3114G>A non_coding_transcript_exon_variant 0.14
fabG1 1673192 c.-248C>A upstream_gene_variant 0.13
fabG1 1673282 c.-158C>A upstream_gene_variant 0.17
fabG1 1673533 p.Ala32Ser missense_variant 0.36
fabG1 1673659 p.Ala74Ser missense_variant 0.15
rpsA 1833413 c.-129G>T upstream_gene_variant 0.18
rpsA 1833928 c.387G>C synonymous_variant 0.15
rpsA 1833970 c.429G>C synonymous_variant 0.2
rpsA 1833976 c.435C>T synonymous_variant 0.19
rpsA 1833979 c.438T>C synonymous_variant 0.19
rpsA 1833991 c.450C>A synonymous_variant 0.2
rpsA 1834000 c.459G>C synonymous_variant 0.2
rpsA 1834012 c.471G>C synonymous_variant 0.2
rpsA 1834015 c.474G>C synonymous_variant 0.2
rpsA 1834021 c.480C>T synonymous_variant 0.2
rpsA 1834030 c.489C>G synonymous_variant 0.2
rpsA 1834177 c.636A>C synonymous_variant 0.21
rpsA 1834199 p.Val220Leu missense_variant 0.14
rpsA 1834294 c.753G>C synonymous_variant 0.12
rpsA 1834303 c.762T>C synonymous_variant 0.12
rpsA 1834306 c.765T>C synonymous_variant 0.12
rpsA 1834348 c.807T>C synonymous_variant 0.27
rpsA 1834361 c.820T>C synonymous_variant 0.31
rpsA 1834366 c.825A>G synonymous_variant 0.31
rpsA 1834387 c.846C>T synonymous_variant 0.33
rpsA 1834396 c.855G>C synonymous_variant 0.33
rpsA 1834411 c.870T>C synonymous_variant 0.36
rpsA 1834417 c.876G>C synonymous_variant 0.33
rpsA 1834423 c.882G>C synonymous_variant 0.33
rpsA 1834451 c.910T>C synonymous_variant 0.3
rpsA 1834456 c.915T>G synonymous_variant 0.3
rpsA 1834468 c.927A>G synonymous_variant 0.36
rpsA 1834489 c.948T>C synonymous_variant 0.27
rpsA 1834513 c.972C>G synonymous_variant 0.2
rpsA 1834520 p.Ala327Ser missense_variant 0.25
rpsA 1834528 c.987T>C synonymous_variant 0.25
rpsA 1834540 c.999G>C synonymous_variant 0.25
rpsA 1834543 c.1002C>G synonymous_variant 0.25
rpsA 1834546 c.1005T>C synonymous_variant 0.25
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.17
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.17
rpsA 1834565 p.Asp342Tyr missense_variant 0.17
rpsA 1834606 c.1065C>T synonymous_variant 0.14
rpsA 1834666 c.1125G>C synonymous_variant 0.12
rpsA 1834690 c.1149T>C synonymous_variant 0.12
rpsA 1834700 p.Gln387Ala missense_variant 0.14
rpsA 1834705 c.1164C>G synonymous_variant 0.14
rpsA 1834732 c.1191T>C synonymous_variant 0.19
rpsA 1834738 p.Glu399Asp missense_variant 0.2
rpsA 1834753 c.1212T>C synonymous_variant 0.23
rpsA 1834759 c.1218A>C synonymous_variant 0.23
rpsA 1834765 p.Glu408Asp missense_variant 0.21
rpsA 1834775 p.Ala412Thr missense_variant 0.2
rpsA 1834786 c.1245A>G synonymous_variant 0.12
rpsA 1834789 c.1248T>C synonymous_variant 0.13
rpsA 1834835 p.Met432Leu missense_variant 0.15
rpsA 1834922 p.Gly461Cys missense_variant 0.15
rpsA 1834930 c.1389A>G synonymous_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 0.38
tlyA 1918027 p.Gly30Cys missense_variant 0.13
ndh 2102062 p.Glu327Asp missense_variant 0.23
ndh 2102083 c.960G>T synonymous_variant 0.14
ndh 2102244 c.799C>A synonymous_variant 0.13
ndh 2102392 c.651C>A synonymous_variant 0.17
ndh 2102686 c.357G>T synonymous_variant 0.15
katG 2154402 c.1710C>A synonymous_variant 0.13
katG 2156049 c.63C>A synonymous_variant 0.15
katG 2156216 c.-105C>A upstream_gene_variant 0.15
katG 2156363 c.-252C>A upstream_gene_variant 0.15
katG 2156527 c.-416C>A upstream_gene_variant 0.14
katG 2156552 c.-441C>A upstream_gene_variant 0.18
katG 2156560 c.-449C>A upstream_gene_variant 0.18
PPE35 2167666 p.Gln983Lys missense_variant 0.13
PPE35 2168677 p.Leu646Ile missense_variant 0.29
PPE35 2169587 c.1026G>C synonymous_variant 0.14
PPE35 2169604 p.Gly337Cys missense_variant 0.13
PPE35 2170033 p.Gly194Ser missense_variant 0.33
PPE35 2170619 c.-7G>T upstream_gene_variant 0.15
Rv1979c 2221748 c.1417C>A synonymous_variant 0.15
Rv1979c 2222249 p.Val306Phe missense_variant 0.13
Rv1979c 2222515 p.Thr217Lys missense_variant 0.18
Rv1979c 2222672 p.Thr165Ala missense_variant 0.18
Rv1979c 2222683 p.Trp161Leu missense_variant 0.17
Rv1979c 2222805 c.360G>T synonymous_variant 0.18
Rv1979c 2222837 p.Ala110Ser missense_variant 0.15
kasA 2517941 c.-174C>G upstream_gene_variant 0.17
kasA 2518198 p.Asp28Glu missense_variant 0.29
kasA 2518559 p.Gly149Cys missense_variant 0.17
kasA 2519095 c.981C>G synonymous_variant 0.22
kasA 2519105 p.Cys331Val missense_variant 0.2
kasA 2519110 p.Asp332Glu missense_variant 0.17
kasA 2519113 p.Gln333His missense_variant 0.17
kasA 2519137 c.1023T>G synonymous_variant 0.17
kasA 2519140 c.1026G>C synonymous_variant 0.17
kasA 2519164 c.1050C>G synonymous_variant 0.15
kasA 2519170 c.1056G>C synonymous_variant 0.15
kasA 2519173 c.1059C>G synonymous_variant 0.15
kasA 2519180 p.Val356Ile missense_variant 0.17
kasA 2519185 c.1071C>G synonymous_variant 0.17
kasA 2519195 p.Thr361Ala missense_variant 0.15
kasA 2519198 c.1084C>T synonymous_variant 0.15
kasA 2519203 c.1089C>T synonymous_variant 0.17
kasA 2519364 c.1250G>T stop_lost&splice_region_variant 0.33
eis 2714645 p.Arg230Ser missense_variant 0.22
eis 2714846 p.Val163Ile missense_variant 0.13
ahpC 2726687 c.495C>A synonymous_variant 0.18
folC 2746998 p.His201Asn missense_variant 0.29
pepQ 2859875 p.Asp182Tyr missense_variant 0.2
pepQ 2860368 c.51C>T synonymous_variant 0.29
ribD 2986950 p.Gly38Cys missense_variant 0.22
ribD 2986963 p.Arg42Leu missense_variant 0.22
ribD 2987246 c.408C>A synonymous_variant 0.18
ribD 2987388 p.Ala184Ser missense_variant 0.15
ribD 2987524 p.Thr229Lys missense_variant 0.14
Rv2752c 3064581 c.1611C>A synonymous_variant 0.25
Rv2752c 3065745 c.447C>A synonymous_variant 0.18
Rv2752c 3066099 p.Met31Ile missense_variant 0.33
ald 3086645 c.-175C>A upstream_gene_variant 0.25
ald 3086679 c.-141C>A upstream_gene_variant 0.22
ald 3087165 p.Ala116Ser missense_variant 0.4
ald 3087497 p.Glu226Asp missense_variant 0.2
fbiD 3339062 c.-56G>A upstream_gene_variant 0.25
fbiD 3339139 p.Gly8Cys missense_variant 0.17
Rv3083 3448709 p.Trp69Leu missense_variant 0.25
Rv3083 3448768 p.Ala89Ser missense_variant 0.2
Rv3083 3448783 p.Val94Phe missense_variant 0.18
Rv3083 3448838 p.Arg112Leu missense_variant 0.2
Rv3083 3448963 p.Pro154Thr missense_variant 0.22
Rv3083 3449216 p.Trp238Leu missense_variant 0.19
Rv3083 3449301 c.798G>T synonymous_variant 0.14
Rv3083 3449961 c.1458C>T synonymous_variant 0.15
fprA 3474379 p.Ala125Thr missense_variant 0.33
whiB7 3568803 c.-124G>T upstream_gene_variant 0.17
whiB7 3568810 c.-131G>T upstream_gene_variant 0.15
Rv3236c 3612813 p.Thr102Ala missense_variant 0.2
fbiA 3640721 p.Pro60Gln missense_variant 0.18
fbiA 3640853 p.Leu104Pro missense_variant 0.25
fbiA 3640999 p.His153Asn missense_variant 0.14
fbiA 3641425 p.His295Tyr missense_variant 0.33
fbiB 3641765 c.231G>T synonymous_variant 0.2
fbiB 3641769 p.Glu79* stop_gained 0.2
fbiB 3641834 c.300G>T synonymous_variant 0.17
fbiB 3641969 c.435C>A synonymous_variant 0.14
fbiB 3641996 c.462C>T synonymous_variant 0.13
fbiB 3642292 p.Arg253Leu missense_variant 0.15
fbiB 3642600 p.Gly356* stop_gained 0.2
fbiB 3642667 p.Gly378Val missense_variant 0.29
alr 3840913 p.Ala170Ser missense_variant 0.18
rpoA 3877686 c.822A>G synonymous_variant 0.12
rpoA 3877743 c.765T>C synonymous_variant 0.14
rpoA 3877749 c.759C>T synonymous_variant 0.15
rpoA 3877764 c.744C>G synonymous_variant 0.15
rpoA 3877770 c.738A>G synonymous_variant 0.14
rpoA 3877773 c.735G>C synonymous_variant 0.17
rpoA 3877776 c.732T>C synonymous_variant 0.17
rpoA 3877785 c.723C>G synonymous_variant 0.14
rpoA 3877803 c.705G>C synonymous_variant 0.12
rpoA 3877808 p.Ile234Val missense_variant 0.12
rpoA 3877818 c.690A>G synonymous_variant 0.14
rpoA 3877836 c.672A>G synonymous_variant 0.18
rpoA 3877839 c.669G>T synonymous_variant 0.18
rpoA 3877856 c.652T>C synonymous_variant 0.25
rpoA 3877860 c.648C>T synonymous_variant 0.27
rpoA 3877875 c.633T>C synonymous_variant 0.3
rpoA 3877881 c.627G>C synonymous_variant 0.22
rpoA 3877887 c.621G>C synonymous_variant 0.25
rpoA 3877893 c.615C>T synonymous_variant 0.25
rpoA 3877905 c.603A>G synonymous_variant 0.25
rpoA 3877908 c.600T>C synonymous_variant 0.22
rpoA 3877920 c.588G>C synonymous_variant 0.25
rpoA 3877926 c.582G>C synonymous_variant 0.2
rpoA 3877962 c.546G>C synonymous_variant 0.2
rpoA 3877971 p.Asp179Glu missense_variant 0.17
rpoA 3877983 c.525C>G synonymous_variant 0.18
rpoA 3878106 c.402G>C synonymous_variant 0.12
rpoA 3878118 c.390T>C synonymous_variant 0.13
rpoA 3878130 c.378C>G synonymous_variant 0.12
rpoA 3878145 p.Pro121Gln missense_variant 0.14
rpoA 3878157 c.351C>G synonymous_variant 0.18
rpoA 3878160 c.348C>G synonymous_variant 0.24
rpoA 3878163 c.345C>T synonymous_variant 0.19
rpoA 3878184 c.324C>T synonymous_variant 0.18
rpoA 3878193 c.315T>C synonymous_variant 0.12
rpoA 3878197 p.Glu104Ala missense_variant 0.12
rpoA 3878205 c.303T>C synonymous_variant 0.12
rpoA 3878217 c.291A>G synonymous_variant 0.12
rpoA 3878502 c.6G>T synonymous_variant 0.18
rpoA 3878605 c.-98G>T upstream_gene_variant 0.29
ddn 3986934 p.Arg31Cys missense_variant 0.22
ddn 3987013 p.Gly57Asp missense_variant 0.2
ddn 3987099 p.Pro86Thr missense_variant 0.15
clpC1 4038181 p.Gly842Cys missense_variant 0.13
clpC1 4038605 c.2100G>A synonymous_variant 0.14
clpC1 4038613 p.Asn698His missense_variant 0.14
clpC1 4038614 c.2091C>T synonymous_variant 0.15
clpC1 4038620 p.Gln695Leu missense_variant 0.15
clpC1 4038623 c.2082A>G synonymous_variant 0.15
clpC1 4038640 p.Asp689Asn missense_variant 0.14
clpC1 4038647 c.2058T>C synonymous_variant 0.15
clpC1 4038650 c.2055C>T synonymous_variant 0.15
clpC1 4038671 c.2034T>G synonymous_variant 0.15
clpC1 4038677 p.Pro676Ala missense_variant 0.15
clpC1 4038683 c.2022T>C synonymous_variant 0.14
clpC1 4038704 c.2001T>C synonymous_variant 0.15
clpC1 4038707 c.1998C>G synonymous_variant 0.15
clpC1 4038710 c.1995G>C synonymous_variant 0.15
clpC1 4038713 c.1992T>C synonymous_variant 0.15
clpC1 4038755 c.1950G>C synonymous_variant 0.14
clpC1 4038773 c.1932T>C synonymous_variant 0.25
clpC1 4038779 c.1926C>G synonymous_variant 0.23
clpC1 4038782 c.1923G>C synonymous_variant 0.25
clpC1 4038790 c.1915C>T synonymous_variant 0.25
clpC1 4038795 p.Ser637Thr missense_variant 0.23
clpC1 4038812 c.1893T>C synonymous_variant 0.31
clpC1 4038815 c.1890G>T synonymous_variant 0.31
clpC1 4038830 c.1875C>T synonymous_variant 0.28
clpC1 4038836 c.1869G>C synonymous_variant 0.29
clpC1 4038845 c.1858_1860delTCGinsAGC synonymous_variant 0.24
clpC1 4038860 c.1845G>C synonymous_variant 0.25
clpC1 4038878 c.1827A>G synonymous_variant 0.3
clpC1 4038881 c.1824C>G synonymous_variant 0.3
clpC1 4038890 c.1815G>A synonymous_variant 0.33
clpC1 4038905 c.1800A>C synonymous_variant 0.33
clpC1 4038908 c.1797C>G synonymous_variant 0.36
clpC1 4038911 c.1794G>T synonymous_variant 0.36
clpC1 4038914 c.1791G>C synonymous_variant 0.36
clpC1 4038917 c.1788C>T synonymous_variant 0.36
clpC1 4038923 c.1782A>G synonymous_variant 0.36
clpC1 4038953 c.1752A>G synonymous_variant 0.27
clpC1 4038956 c.1749T>C synonymous_variant 0.3
clpC1 4038965 c.1740T>C synonymous_variant 0.33
clpC1 4038971 c.1734T>C synonymous_variant 0.22
clpC1 4038974 c.1731T>C synonymous_variant 0.22
clpC1 4038980 c.1725C>T synonymous_variant 0.33
clpC1 4038989 c.1716T>C synonymous_variant 0.33
clpC1 4038997 c.1708T>C synonymous_variant 0.38
clpC1 4039001 p.Asn568Ala missense_variant 0.33
clpC1 4039022 c.1683A>G synonymous_variant 0.29
clpC1 4039112 c.1593C>G synonymous_variant 0.14
clpC1 4039118 c.1587C>G synonymous_variant 0.15
clpC1 4039121 c.1584T>C synonymous_variant 0.17
clpC1 4039409 c.1296T>C synonymous_variant 0.13
clpC1 4039412 c.1293T>G synonymous_variant 0.12
clpC1 4039415 p.Glu430Asp missense_variant 0.12
clpC1 4039430 c.1275T>C synonymous_variant 0.12
clpC1 4039442 c.1263A>G synonymous_variant 0.12
clpC1 4039517 c.1188C>G synonymous_variant 0.17
clpC1 4039553 c.1152C>G synonymous_variant 0.14
clpC1 4039556 c.1149G>C synonymous_variant 0.14
clpC1 4039565 c.1140G>C synonymous_variant 0.13
clpC1 4039570 p.Met379Leu missense_variant 0.13
clpC1 4039571 c.1134G>C synonymous_variant 0.13
clpC1 4039575 p.Ala377Gly missense_variant 0.13
clpC1 4039577 c.1128T>C synonymous_variant 0.13
clpC1 4039586 c.1119G>C synonymous_variant 0.14
clpC1 4039593 p.Arg371Leu missense_variant 0.13
clpC1 4039598 c.1107C>T synonymous_variant 0.14
clpC1 4039610 c.1095G>T synonymous_variant 0.12
clpC1 4039616 c.1089G>C synonymous_variant 0.12
clpC1 4039622 c.1083C>T synonymous_variant 0.14
clpC1 4039640 c.1065C>G synonymous_variant 0.19
clpC1 4039649 c.1056G>C synonymous_variant 0.14
clpC1 4039652 c.1053G>C synonymous_variant 0.18
clpC1 4039694 c.1011G>C synonymous_variant 0.14
clpC1 4039718 c.987C>G synonymous_variant 0.29
clpC1 4039724 c.981A>G synonymous_variant 0.31
clpC1 4039733 c.972G>C synonymous_variant 0.38
clpC1 4039751 c.954A>G synonymous_variant 0.38
clpC1 4039757 c.948A>G synonymous_variant 0.4
clpC1 4039760 c.945T>C synonymous_variant 0.38
clpC1 4039766 c.939T>C synonymous_variant 0.38
clpC1 4039769 c.936C>G synonymous_variant 0.38
clpC1 4039775 c.930G>C synonymous_variant 0.35
clpC1 4039778 c.927A>G synonymous_variant 0.35
clpC1 4039787 c.916_918delTCGinsAGC synonymous_variant 0.38
clpC1 4039808 p.Glu299Asp missense_variant 0.15
clpC1 4039817 c.888A>T synonymous_variant 0.46
clpC1 4039820 c.885T>C synonymous_variant 0.46
clpC1 4039823 c.882T>A synonymous_variant 0.46
clpC1 4039831 c.874T>C synonymous_variant 0.46
clpC1 4039832 c.873C>G synonymous_variant 0.46
clpC1 4039850 c.855T>C synonymous_variant 0.43
clpC1 4039865 c.840T>C synonymous_variant 0.36
clpC1 4039898 c.807C>G synonymous_variant 0.18
clpC1 4039931 c.774T>C synonymous_variant 0.31
clpC1 4039934 c.771G>C synonymous_variant 0.31
clpC1 4039937 c.768G>C synonymous_variant 0.31
clpC1 4039946 c.759A>C synonymous_variant 0.36
clpC1 4039949 c.756G>C synonymous_variant 0.36
clpC1 4039952 c.753T>C synonymous_variant 0.31
clpC1 4039979 c.726C>G synonymous_variant 0.33
clpC1 4039991 c.714G>C synonymous_variant 0.27
clpC1 4040015 c.690G>C synonymous_variant 0.28
clpC1 4040021 c.684A>C synonymous_variant 0.28
clpC1 4040024 c.681A>G synonymous_variant 0.31
clpC1 4040030 c.675C>G synonymous_variant 0.28
clpC1 4040033 c.672G>C synonymous_variant 0.28
clpC1 4040042 c.663C>T synonymous_variant 0.29
clpC1 4040057 c.648C>T synonymous_variant 0.25
clpC1 4040087 c.618G>C synonymous_variant 0.17
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.17
clpC1 4040093 c.612C>T synonymous_variant 0.17
clpC1 4040195 c.510G>C synonymous_variant 0.22
clpC1 4040200 c.505T>C synonymous_variant 0.22
clpC1 4040201 c.504C>A synonymous_variant 0.22
clpC1 4040204 c.501G>C synonymous_variant 0.22
clpC1 4040207 c.498T>G synonymous_variant 0.25
clpC1 4040213 p.Ser164Asn missense_variant 0.25
clpC1 4040228 c.477G>C synonymous_variant 0.22
clpC1 4040237 c.468C>T synonymous_variant 0.22
clpC1 4040246 c.459C>A synonymous_variant 0.25
clpC1 4040249 c.456A>G synonymous_variant 0.25
clpC1 4040258 c.447G>A synonymous_variant 0.25
clpC1 4040267 c.438A>G synonymous_variant 0.25
clpC1 4040341 p.Gln122Lys missense_variant 0.33
clpC1 4040411 c.294T>C synonymous_variant 0.17
clpC1 4040426 c.279T>C synonymous_variant 0.15
clpC1 4040431 c.274T>C synonymous_variant 0.14
clpC1 4040433 c.271_272delAGinsTC synonymous_variant 0.13
clpC1 4040435 c.270G>C synonymous_variant 0.13
clpC1 4040438 c.267G>A synonymous_variant 0.14
clpC1 4040450 c.255A>G synonymous_variant 0.17
clpC1 4040459 c.246C>G synonymous_variant 0.15
clpC1 4040462 c.243C>T synonymous_variant 0.14
clpC1 4040465 c.240T>C synonymous_variant 0.14
clpC1 4040471 c.234T>C synonymous_variant 0.14
clpC1 4040480 c.225T>C synonymous_variant 0.14
clpC1 4040522 c.183T>C synonymous_variant 0.19
clpC1 4040531 c.174T>C synonymous_variant 0.19
clpC1 4040537 c.168G>C synonymous_variant 0.2
clpC1 4040540 c.165G>C synonymous_variant 0.2
clpC1 4040590 p.His39Asn missense_variant 0.2
clpC1 4040636 c.69C>A synonymous_variant 0.22
panD 4044225 p.Asp19Glu missense_variant 0.15
embC 4240822 c.960C>A synonymous_variant 0.15
embC 4240826 p.Ala322Ser missense_variant 0.15
embC 4240868 p.His336Asn missense_variant 0.22
embC 4240941 p.Ser360Ile missense_variant 0.18
embA 4242751 c.-482G>T upstream_gene_variant 0.25
embA 4243373 p.Gln47His missense_variant 0.2
embA 4243471 p.Ala80Asp missense_variant 0.25
embA 4243568 c.336C>T synonymous_variant 0.29
embA 4243721 c.489G>T synonymous_variant 0.22
embA 4244083 p.Ala284Asp missense_variant 0.22
embA 4245280 p.Arg683Leu missense_variant 0.13
embA 4246411 c.3181delC frameshift_variant 0.33
embA 4246483 p.Trp1084Leu missense_variant 0.22
embB 4246623 p.Gly37Val missense_variant 0.17
embB 4246762 c.249G>T synonymous_variant 0.14
embB 4247183 p.Gly224Trp missense_variant 0.18
embB 4248469 p.Tyr652* stop_gained 0.15
embB 4249594 c.3081G>A synonymous_variant 0.13
embB 4249625 p.Gly1038Trp missense_variant 0.14
aftB 4267882 p.Gly319Ser missense_variant 0.15
aftB 4268064 p.Ser258* stop_gained 0.2
aftB 4268440 p.Asp133His missense_variant 0.2
aftB 4268481 p.Pro119Leu missense_variant 0.2
aftB 4268630 c.207G>T synonymous_variant 0.29
aftB 4269234 c.-398A>G upstream_gene_variant 0.33
aftB 4269459 c.-623G>T upstream_gene_variant 0.15
ubiA 4269634 p.Ser67* stop_gained 0.22
ethA 4326068 p.Arg469Leu missense_variant 0.15
ethA 4326167 p.Pro436Gln missense_variant 0.2
ethA 4326325 c.1149G>T synonymous_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 0.32
whiB6 4338648 c.-127A>T upstream_gene_variant 0.17
gid 4407588 c.615A>G synonymous_variant 0.12
gid 4408357 c.-155C>A upstream_gene_variant 0.15