Run ID: 5178fad0-746a-4886-af30-f38a773ea5c0
Sample name:
Date: 18-03-2024 14:05:32
Number of reads: 28677052
Percentage reads mapped: 78.06
Median coverage: 330
Strain: lineage6.3.1
Spoligotype:
Drug-resistance: Other
| Lineage | Family | RDs | Frequency |
|---|---|---|---|
| lineage6 | West-Africa 2 | RD702 | 1.0 |
| lineage6.3 | West-Africa 2 | RD702 | 1.0 |
| lineage6.3.1 | West-Africa 2 | RD702 | 1.0 |
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | rrs | n.888G>A | Uncertain significance | |
| amikacin | ||||
| kanamycin | ||||
| capreomycin | ||||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|---|---|---|---|---|---|---|
| rrs | 1472733 | n.888G>A | non_coding_transcript_exon_variant | 0.59 | streptomycin | Uncertain significance |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrB | 6446 | p.Ala403Ser | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9143 | c.1842T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| fgd1 | 491668 | p.Lys296Glu | missense_variant | 1.0 | delamanid | Uncertain significance |
| fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | delamanid | |
| mshA | 576108 | p.Ala254Gly | missense_variant | 0.24 | ethionamide | Uncertain significance |
| isoniazid | ||||||
| rpoB | 760969 | p.Ser388Leu | missense_variant | 1.0 | rifampicin | Uncertain significance |
| rpoB | 761723 | p.Glu639Asp | missense_variant | 0.99 | rifampicin | Uncertain significance |
| rpoC | 763031 | c.-339T>C | upstream_gene_variant | 0.99 | rifampicin | |
| mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| mmpL5 | 776100 | p.Thr794Ile | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
| fbiC | 1302899 | c.-32A>G | upstream_gene_variant | 1.0 | delamanid | Uncertain significance |
| Rv1258c | 1406363 | c.978A>G | synonymous_variant | 1.0 | streptomycin | |
| pyrazinamide | ||||||
| isoniazid | ||||||
| atpE | 1461251 | c.207G>T | synonymous_variant | 1.0 | bedaquiline | |
| rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471896 | n.51T>C | non_coding_transcript_exon_variant | 0.26 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471900 | n.55C>T | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1471911 | n.66C>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472137 | n.292G>A | non_coding_transcript_exon_variant | 0.21 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472151 | n.306C>T | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472172 | n.327T>C | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472203 | n.358G>A | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472378 | n.533G>T | non_coding_transcript_exon_variant | 0.27 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472379 | n.534T>C | non_coding_transcript_exon_variant | 0.28 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472380 | n.535G>C | non_coding_transcript_exon_variant | 0.28 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472396 | n.551A>T | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472400 | n.555C>T | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472517 | n.672T>A | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472518 | n.673G>T | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472537 | n.692C>T | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472544 | n.699C>A | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472545 | n.700A>T | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472566 | n.721G>A | non_coding_transcript_exon_variant | 0.51 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472571 | n.726G>C | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472579 | n.734G>C | non_coding_transcript_exon_variant | 0.35 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472580 | n.735C>T | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472581 | n.736A>T | non_coding_transcript_exon_variant | 0.34 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472598 | n.753A>C | non_coding_transcript_exon_variant | 0.39 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472599 | n.754G>T | non_coding_transcript_exon_variant | 0.39 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.52 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472655 | n.810G>A | non_coding_transcript_exon_variant | 0.3 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472658 | n.813G>A | non_coding_transcript_exon_variant | 0.24 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472697 | n.852T>C | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472716 | n.871C>T | non_coding_transcript_exon_variant | 0.34 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472744 | n.899A>G | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472781 | n.936C>T | non_coding_transcript_exon_variant | 0.72 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472793 | n.948A>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472803 | n.958T>A | non_coding_transcript_exon_variant | 0.56 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472824 | n.979T>A | non_coding_transcript_exon_variant | 0.23 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472827 | n.982G>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472828 | n.983T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.46 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.47 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473053 | n.1208T>A | non_coding_transcript_exon_variant | 0.47 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.45 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473062 | n.1217T>A | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473068 | n.1223A>G | non_coding_transcript_exon_variant | 0.3 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473081 | n.1236C>T | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473177 | n.1332G>A | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473192 | n.1347A>G | non_coding_transcript_exon_variant | 0.47 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473199 | n.1356delA | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473205 | n.1360T>C | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | Uncertain significance | |||||
| rrs | 1473327 | n.1482A>G | non_coding_transcript_exon_variant | 0.11 | linezolid | |
| kanamycin | Uncertain significance | |||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473328 | n.1483C>T | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1473352 | n.1507C>T | non_coding_transcript_exon_variant | 0.4 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1474218 | n.561T>A | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1474228 | n.571T>C | non_coding_transcript_exon_variant | 0.41 | linezolid | |
| rrl | 1474249 | n.592G>T | non_coding_transcript_exon_variant | 0.36 | linezolid | |
| rrl | 1474252 | n.595T>A | non_coding_transcript_exon_variant | 0.33 | linezolid | |
| rrl | 1475552 | n.1895G>C | non_coding_transcript_exon_variant | 0.15 | linezolid | |
| rrl | 1475574 | n.1917C>A | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| rrl | 1475704 | n.2047C>T | non_coding_transcript_exon_variant | 0.1 | linezolid | |
| rrl | 1475713 | n.2056C>G | non_coding_transcript_exon_variant | 0.18 | linezolid | |
| rrl | 1475716 | n.2059A>G | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475717 | n.2060C>G | non_coding_transcript_exon_variant | 0.19 | linezolid | |
| rrl | 1475783 | n.2126T>G | non_coding_transcript_exon_variant | 0.25 | linezolid | |
| rrl | 1475803 | n.2146T>C | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| rrl | 1475804 | n.2147G>C | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| rrl | 1475816 | n.2159C>G | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| rrl | 1475817 | n.2160A>G | non_coding_transcript_exon_variant | 0.54 | linezolid | |
| rrl | 1475858 | n.2201T>C | non_coding_transcript_exon_variant | 0.35 | linezolid | |
| rrl | 1475866 | n.2209T>A | non_coding_transcript_exon_variant | 0.3 | linezolid | |
| rrl | 1475874 | n.2217C>T | non_coding_transcript_exon_variant | 0.16 | linezolid | |
| rrl | 1476135 | n.2478T>C | non_coding_transcript_exon_variant | 0.12 | linezolid | |
| rrl | 1476141 | n.2484A>G | non_coding_transcript_exon_variant | 0.26 | linezolid | |
| rrl | 1476153 | n.2496T>C | non_coding_transcript_exon_variant | 0.32 | linezolid | |
| rrl | 1476165 | n.2508T>G | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| rrl | 1476225 | n.2568T>G | non_coding_transcript_exon_variant | 0.29 | linezolid | |
| rrl | 1476227 | n.2570C>T | non_coding_transcript_exon_variant | 0.3 | linezolid | |
| rrl | 1476229 | n.2572C>T | non_coding_transcript_exon_variant | 0.31 | linezolid | |
| rrl | 1476250 | n.2593C>G | non_coding_transcript_exon_variant | 0.63 | linezolid | |
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1476257 | n.2600G>C | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.65 | linezolid | Uncertain significance |
| rrl | 1476280 | n.2623A>C | non_coding_transcript_exon_variant | 0.37 | linezolid | |
| rrl | 1476332 | n.2675G>C | non_coding_transcript_exon_variant | 0.22 | linezolid | |
| rrl | 1476338 | n.2681C>T | non_coding_transcript_exon_variant | 0.28 | linezolid | Uncertain significance |
| rrl | 1476353 | n.2696G>T | non_coding_transcript_exon_variant | 0.42 | linezolid | |
| rrl | 1476358 | n.2701T>C | non_coding_transcript_exon_variant | 0.49 | linezolid | |
| rrl | 1476369 | n.2712C>T | non_coding_transcript_exon_variant | 0.5 | linezolid | |
| rrl | 1476372 | n.2715T>C | non_coding_transcript_exon_variant | 0.53 | linezolid | |
| rrl | 1476382 | n.2725A>G | non_coding_transcript_exon_variant | 0.57 | linezolid | |
| rrl | 1476383 | n.2726T>A | non_coding_transcript_exon_variant | 0.57 | linezolid | |
| rrl | 1476425 | n.2768G>T | non_coding_transcript_exon_variant | 0.64 | linezolid | |
| rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.62 | linezolid | |
| rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 0.65 | linezolid | |
| rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.67 | linezolid | |
| rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.43 | linezolid | |
| rrl | 1476514 | n.2857C>T | non_coding_transcript_exon_variant | 0.17 | linezolid | |
| inhA | 1674434 | p.Val78Ala | missense_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | |
| ndh | 2102022 | p.Lys341Glu | missense_variant | 1.0 | ethionamide | |
| isoniazid | Uncertain significance | |||||
| ndh | 2102694 | p.Val117Ile | missense_variant | 1.0 | ethionamide | Uncertain significance |
| isoniazid | Uncertain significance | |||||
| katG | 2154724 | p.Arg463Leu | missense_variant | 1.0 | isoniazid | Uncertain significance |
| katG | 2155503 | c.609C>T | synonymous_variant | 1.0 | isoniazid | |
| PPE35 | 2167926 | p.Leu896Ser | missense_variant | 0.99 | pyrazinamide | Uncertain significance |
| Rv1979c | 2222308 | p.Asp286Gly | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| Rv1979c | 2222852 | p.Ala105Thr | missense_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Uncertain significance |
| bedaquiline | Uncertain significance | |||||
| kasA | 2518132 | c.18C>T | synonymous_variant | 1.0 | isoniazid | |
| ald | 3086728 | c.-92C>T | upstream_gene_variant | 1.0 | cycloserine | |
| ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
| ald | 3086958 | p.Asp47Tyr | missense_variant | 1.0 | cycloserine | |
| ald | 3087084 | c.266delA | frameshift_variant | 1.0 | cycloserine | |
| Rv3083 | 3449781 | c.1278G>A | synonymous_variant | 1.0 | ethionamide | |
| fprA | 3473996 | c.-11_-10insA | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| fprA | 3474911 | p.Val302Gly | missense_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| fprA | 3475159 | p.Asn385Asp | missense_variant | 1.0 | capreomycin | Uncertain significance |
| amikacin | Uncertain significance | |||||
| rpoA | 3877696 | p.Thr271Ile | missense_variant | 1.0 | rifampicin | Uncertain significance |
| clpC1 | 4040489 | c.216G>A | synonymous_variant | 1.0 | pyrazinamide | |
| embC | 4240671 | p.Thr270Ile | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embC | 4241843 | p.Leu661Ile | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 | ethambutol | |
| embA | 4244220 | c.988C>T | synonymous_variant | 1.0 | ethambutol | |
| embA | 4244379 | p.Pro383Ser | missense_variant | 1.0 | ethambutol | Uncertain significance |
| embB | 4246864 | c.351C>T | synonymous_variant | 1.0 | ethambutol | |
| embB | 4247646 | p.Glu378Ala | missense_variant | 1.0 | ethambutol | Uncertain significance |
| aftB | 4268477 | c.360C>T | synonymous_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| aftB | 4269351 | c.-515C>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| ubiA | 4269387 | p.Glu149Asp | missense_variant | 1.0 | ethambutol | Uncertain significance |
| aftB | 4269522 | c.-686C>T | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| aftB | 4269606 | c.-770T>C | upstream_gene_variant | 1.0 | capreomycin | |
| amikacin | ||||||
| ethA | 4326465 | p.Ile337Val | missense_variant | 1.0 | ethionamide | Uncertain significance |
| whiB6 | 4338176 | p.Ala116Thr | missense_variant | 0.11 | streptomycin | |
| capreomycin | ||||||
| amikacin | ||||||
| whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
| capreomycin | Uncertain significance | |||||
| amikacin | Uncertain significance | |||||
| gid | 4407588 | c.615A>G | synonymous_variant | 1.0 | streptomycin |
