TB-Profiler result

Run: ERR2509886
Summary

Run ID: ERR2509886

Sample name:

Date: 31-03-2023 18:32:56

Number of reads: 408496

Percentage reads mapped: 61.54

Strain: lineage3

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.25 rifampicin
rpoB 761196 p.Leu464Met missense_variant 0.12 rifampicin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.13 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.33 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 761027 c.1221A>G synonymous_variant 0.12
rpoB 761030 c.1224G>C synonymous_variant 0.16
rpoB 761037 c.1231T>C synonymous_variant 0.24
rpoB 761051 c.1245G>C synonymous_variant 0.19
rpoB 761054 c.1248G>C synonymous_variant 0.18
rpoB 761057 c.1251G>C synonymous_variant 0.18
rpoB 761060 c.1254C>G synonymous_variant 0.18
rpoB 761084 c.1278C>A synonymous_variant 0.15
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.19
rpoB 761096 c.1290G>C synonymous_variant 0.19
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.2
rpoB 761102 c.1296A>G synonymous_variant 0.25
rpoB 761123 c.1317G>C synonymous_variant 0.12
rpoB 761126 c.1320G>C synonymous_variant 0.17
rpoB 761132 c.1326G>C synonymous_variant 0.22
rpoB 761133 c.1327T>C synonymous_variant 0.25
rpoB 761150 c.1344A>T synonymous_variant 0.17
rpoB 761159 c.1353G>C synonymous_variant 0.22
rpoB 761165 c.1359G>C synonymous_variant 0.22
rpoB 761180 c.1374A>C synonymous_variant 0.13
rpoB 761186 p.Glu460Asp missense_variant 0.13
rpoB 761195 c.1389G>C synonymous_variant 0.12
rpoB 761954 c.2148C>T synonymous_variant 1.0
rpoB 762134 c.2328C>T synonymous_variant 0.14
rpoB 762143 c.2337T>C synonymous_variant 0.25
rpoB 762149 c.2343G>C synonymous_variant 0.25
rpoB 762156 p.Val784Ile missense_variant 0.21
rpoB 762167 c.2361T>C synonymous_variant 0.15
rpoB 762176 c.2370T>C synonymous_variant 0.22
rpoB 762177 p.Arg791Thr missense_variant 0.22
rpoB 762181 p.Asp792Ala missense_variant 0.22
rpoB 762185 c.2379G>C synonymous_variant 0.22
rpoB 762194 c.2388G>C synonymous_variant 0.24
rpoB 762200 c.2394C>T synonymous_variant 0.19
rpoB 762218 c.2412T>C synonymous_variant 0.19
rpoB 762233 c.2427G>C synonymous_variant 0.25
rpoB 762234 p.Pro810Ser missense_variant 0.25
rpoB 762239 c.2433G>A synonymous_variant 0.25
rpoB 762245 c.2439G>C synonymous_variant 0.36
rpoB 762248 c.2442G>C synonymous_variant 0.18
rpoB 762254 c.2448T>C synonymous_variant 0.4
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763043 c.-327G>C upstream_gene_variant 0.17
rpoC 763053 c.-317T>C upstream_gene_variant 0.14
rpoC 763067 c.-303C>G upstream_gene_variant 0.13
rpoC 763070 c.-300T>C upstream_gene_variant 0.13
rpoB 763077 p.Val1091Thr missense_variant 0.14
rpoC 763103 c.-267G>C upstream_gene_variant 0.14
rpoC 763109 c.-261C>T upstream_gene_variant 0.13
rpoC 763115 c.-255T>C upstream_gene_variant 0.14
rpoB 763119 p.Asn1105Asp missense_variant 0.15
rpoC 763127 c.-243G>C upstream_gene_variant 0.13
rpoC 763133 c.-237G>C upstream_gene_variant 0.14
rpoC 763148 c.-222G>C upstream_gene_variant 0.12
rpoC 763492 c.123G>C synonymous_variant 0.18
rpoC 763528 c.159G>C synonymous_variant 0.2
rpoC 763531 c.162G>C synonymous_variant 0.27
rpoC 763534 c.165T>C synonymous_variant 0.18
rpoC 763546 c.177A>G synonymous_variant 0.23
rpoC 763550 p.Tyr61Ala missense_variant 0.23
rpoC 763570 c.201G>C synonymous_variant 0.31
rpoC 763578 p.Phe70Tyr missense_variant 0.36
rpoC 763606 c.237C>A synonymous_variant 0.18
rpoC 763615 c.246G>C synonymous_variant 0.23
rpoC 763618 c.249C>T synonymous_variant 0.14
rpoC 763622 p.Ala85Ser missense_variant 0.27
rpoC 763633 c.264T>C synonymous_variant 0.2
rpoC 763636 c.267T>C synonymous_variant 0.14
rpoC 763642 c.273G>C synonymous_variant 0.38
rpoC 763647 p.Gly93Ala missense_variant 0.12
rpoC 763655 p.Glu96Asn missense_variant 0.11
rpoC 763660 c.291T>G synonymous_variant 0.33
rpoC 763666 c.297G>C synonymous_variant 0.35
rpoC 763675 c.306C>G synonymous_variant 0.32
rpoC 763699 c.330G>T synonymous_variant 0.4
rpoC 763708 c.339G>C synonymous_variant 0.44
rpoC 763714 c.345G>C synonymous_variant 0.38
rpoC 763717 c.348T>C synonymous_variant 0.38
rpoC 763718 p.Leu117Val missense_variant 0.31
rpoC 763723 c.354G>C synonymous_variant 0.38
rpoC 763724 p.Asp119Asn missense_variant 0.38
rpoC 763729 c.360G>C synonymous_variant 0.38
rpoC 763732 c.363C>G synonymous_variant 0.38
rpoC 763735 c.366G>C synonymous_variant 0.38
rpoC 763744 c.375G>C synonymous_variant 0.36
rpoC 763751 p.Ile128Val missense_variant 0.46
rpoC 763772 p.Val135Met missense_variant 0.4
rpoC 763781 p.Ser138Glu missense_variant 0.36
rpoC 764485 c.1116G>C synonymous_variant 0.38
rpoC 764491 c.1122G>T synonymous_variant 0.36
rpoC 764497 c.1128A>G synonymous_variant 0.42
rpoC 764498 p.Ser377Ala missense_variant 0.15
rpoC 764503 c.1134G>T synonymous_variant 0.27
rpoC 764509 c.1140G>C synonymous_variant 0.42
rpoC 764512 c.1143G>C synonymous_variant 0.29
rpoC 764521 c.1152T>C synonymous_variant 0.29
rpoC 764530 c.1161C>T synonymous_variant 0.24
rpoC 764536 c.1167G>C synonymous_variant 0.32
rpoC 764539 c.1170C>G synonymous_variant 0.14
rpoC 764543 p.Thr392Ala missense_variant 0.27
rpoC 764548 c.1179G>C synonymous_variant 0.35
rpoC 764566 c.1197C>G synonymous_variant 0.29
rpoC 764572 c.1203G>C synonymous_variant 0.13
rpoC 764573 p.Leu402Ile missense_variant 0.35
rpoC 764578 c.1209C>G synonymous_variant 0.35
rpoC 764581 c.1212T>C synonymous_variant 0.43
rpoC 764582 p.Leu405Met missense_variant 0.43
rpoC 764593 c.1224C>T synonymous_variant 0.35
rpoC 764602 c.1233C>T synonymous_variant 0.24
rpoC 764605 c.1236G>T synonymous_variant 0.46
rpoC 764611 c.1242G>T synonymous_variant 0.44
rpoC 764620 c.1251G>C synonymous_variant 0.2
rpoC 764623 c.1254C>G synonymous_variant 0.12
rpoC 764626 c.1257C>T synonymous_variant 0.25
rpoC 764632 c.1263T>C synonymous_variant 0.33
rpoC 764647 c.1278C>T synonymous_variant 0.27
rpoC 764650 c.1281G>T synonymous_variant 0.33
rpoC 764653 c.1284G>C synonymous_variant 0.36
rpoC 764656 c.1287C>T synonymous_variant 0.25
rpoC 764662 c.1293G>C synonymous_variant 0.38
rpoC 764677 c.1308C>G synonymous_variant 0.26
rpoC 764678 p.Lys437Gln missense_variant 0.26
rpoC 764683 c.1314G>C synonymous_variant 0.2
rpoC 764692 c.1323C>T synonymous_variant 0.28
rpoC 764706 p.Leu446Gln missense_variant 0.27
rpoC 764731 c.1362G>C synonymous_variant 0.14
rpoC 764737 c.1368G>C synonymous_variant 0.14
rpoC 764746 c.1377G>C synonymous_variant 0.16
rpoC 764749 c.1380G>C synonymous_variant 0.11
rpoC 764764 c.1395T>C synonymous_variant 0.11
rpoC 765967 c.2598C>T synonymous_variant 0.12
rpoC 765988 c.2619G>C synonymous_variant 0.14
rpoC 765991 c.2622C>G synonymous_variant 0.14
rpoC 765994 c.2625A>T synonymous_variant 0.14
rpoC 766003 c.2634G>C synonymous_variant 0.11
rpoC 766009 c.2640G>C synonymous_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpS5 778970 c.-65A>G upstream_gene_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781832 c.273T>C synonymous_variant 0.11
rpsL 781835 c.276T>C synonymous_variant 0.11
fbiC 1305067 p.Val713Met missense_variant 0.12
atpE 1461086 c.42A>G synonymous_variant 0.33
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.13
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.14
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.34
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.37
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.39
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.41
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.54
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.5
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.42
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.22
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.24
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.33
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.12
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.15
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.17
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.16
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.3
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.25
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.24
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.24
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.28
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.33
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.21
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.12
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.42
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.38
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.35
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.25
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.2
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.42
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.29
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.23
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.25
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.17
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.22
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.29
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.3
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.22
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.29
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.15
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.38
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.25
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.38
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.34
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.34
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.35
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.11
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.22
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.21
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.15
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.2
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.22
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.32
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.27
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.43
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.35
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.38
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.14
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.15
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.11
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.54
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.36
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.47
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.74
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.64
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.69
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.75
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.51
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.55
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.6
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.63
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.64
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.3
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.35
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.67
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.69
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.69
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.14
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.66
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.53
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.47
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.71
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.66
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.54
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.55
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.56
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.66
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.58
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.63
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.51
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.47
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.48
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.6
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.12
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.57
rrl 1473384 n.-274A>G upstream_gene_variant 0.26
rrl 1473534 n.-124T>A upstream_gene_variant 0.12
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.23
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.15
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.17
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.21
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.24
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.21
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.24
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.12
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.24
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.15
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.14
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.21
rrl 1474921 n.1264C>T non_coding_transcript_exon_variant 0.14
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.22
rrl 1475713 n.2056C>T non_coding_transcript_exon_variant 0.2
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.25
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 0.13
rrl 1475757 n.2101_2104delACCC non_coding_transcript_exon_variant 0.3
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.26
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.14
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.22
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.22
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.26
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.17
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.26
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.26
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.18
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.18
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.15
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.14
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.14
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.11
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.11
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.12
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.66
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.69
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.56
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.48
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.57
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.45
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.3
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.22
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.2
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.12
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.16
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.16
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.19
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.12
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.12
fabG1 1673800 p.Gln121Lys missense_variant 0.14
rpsA 1833874 c.333T>C synonymous_variant 0.17
rpsA 1833884 p.Thr115Asp missense_variant 0.16
rpsA 1833893 p.Ala118Lys missense_variant 0.16
rpsA 1833896 p.Leu119Ile missense_variant 0.17
rpsA 1833905 p.Lys122Glu missense_variant 0.22
rpsA 1833912 p.Glu124Gly missense_variant 0.21
rpsA 1833915 p.Ala125Val missense_variant 0.21
rpsA 1833920 p.Lys127Glu missense_variant 0.17
rpsA 1833928 c.387G>C synonymous_variant 0.21
rpsA 1833949 c.408T>C synonymous_variant 0.19
rpsA 1833955 c.414G>C synonymous_variant 0.24
rpsA 1833961 c.420C>G synonymous_variant 0.17
rpsA 1833970 c.429G>C synonymous_variant 0.22
rpsA 1833979 c.438T>C synonymous_variant 0.23
rpsA 1833985 c.444G>C synonymous_variant 0.11
rpsA 1833988 c.447C>G synonymous_variant 0.11
rpsA 1833994 c.453G>C synonymous_variant 0.12
rpsA 1833997 c.456G>C synonymous_variant 0.12
rpsA 1834012 c.471G>C synonymous_variant 0.24
rpsA 1834024 c.483G>C synonymous_variant 0.14
rpsA 1834040 p.Lys167Gln missense_variant 0.14
rpsA 1834046 p.Ile169Leu missense_variant 0.13
rpsA 1834264 c.723G>C synonymous_variant 0.13
rpsA 1834294 c.753G>C synonymous_variant 0.11
rpsA 1834298 p.Gln253Glu missense_variant 0.11
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170082 c.531T>G synonymous_variant 0.4
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
eis 2715193 p.Val47Glu missense_variant 0.15
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
pepQ 2859578 p.Ile281Leu missense_variant 0.15
Rv2752c 3065602 p.Asp197Gly missense_variant 0.18
thyA 3073756 p.Phe239Ser missense_variant 0.17
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449883 p.Trp460* stop_gained 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474809 p.Val268Ala missense_variant 0.15
Rv3236c 3612835 c.282T>G synonymous_variant 0.29
alr 3841473 c.-53G>A upstream_gene_variant 1.0
ddn 3986878 c.36delG frameshift_variant 1.0
embC 4240648 c.786C>T synonymous_variant 0.25
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245927 p.Thr899Ala missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407775 p.Asp143Gly missense_variant 1.0