TB-Profiler result

Run: ERR4820266
Summary

Run ID: ERR4820266

Sample name:

Date: 01-04-2023 16:35:00

Number of reads: 394169

Percentage reads mapped: 76.29

Strain: lineage3

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.38 rifampicin
rpoB 761196 p.Leu464Met missense_variant 0.29 rifampicin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.12 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6707 p.Lys490Glu missense_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7823 c.522G>A synonymous_variant 0.18
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 576060 p.Val238Asp missense_variant 0.5
ccsA 620468 p.Ser193Asn missense_variant 0.2
ccsA 620532 c.642T>G synonymous_variant 0.33
ccsA 620694 c.804C>A synonymous_variant 0.4
rpoB 759615 c.-192A>C upstream_gene_variant 0.5
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 759859 p.Pro18Gln missense_variant 0.18
rpoB 760636 p.Pro277Leu missense_variant 0.2
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.25
rpoB 761102 c.1296A>G synonymous_variant 0.29
rpoB 761123 c.1317G>C synonymous_variant 0.25
rpoB 761126 c.1320G>C synonymous_variant 0.25
rpoB 761132 c.1326G>C synonymous_variant 0.25
rpoB 761133 c.1327T>C synonymous_variant 0.38
rpoB 761150 c.1344A>T synonymous_variant 0.29
rpoB 761165 c.1359G>C synonymous_variant 0.33
rpoB 761186 p.Glu460Asp missense_variant 0.29
rpoB 761195 c.1389G>C synonymous_variant 0.29
rpoB 761201 c.1395G>A synonymous_variant 0.29
rpoB 761207 c.1401C>A synonymous_variant 0.25
rpoB 761213 c.1407G>C synonymous_variant 0.25
rpoB 761219 c.1413G>C synonymous_variant 0.25
rpoB 761231 c.1425C>T synonymous_variant 0.33
rpoB 761234 c.1428G>T synonymous_variant 0.33
rpoB 762099 p.Arg765Cys missense_variant 0.22
rpoC 762434 c.-936T>G upstream_gene_variant 0.88
rpoC 762983 c.-387C>T upstream_gene_variant 0.12
rpoC 762989 c.-381G>C upstream_gene_variant 0.12
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763038 p.Thr1078Ala missense_variant 0.11
rpoC 763053 c.-317T>C upstream_gene_variant 0.11
rpoC 763070 c.-300T>C upstream_gene_variant 0.12
rpoB 763078 p.Val1091Ala missense_variant 0.12
rpoC 763103 c.-267G>C upstream_gene_variant 0.13
rpoC 763507 c.138G>C synonymous_variant 0.18
rpoC 763528 c.159G>C synonymous_variant 0.21
rpoC 763531 c.162G>C synonymous_variant 0.21
rpoC 763534 c.165T>C synonymous_variant 0.21
rpoC 763537 c.168C>G synonymous_variant 0.2
rpoC 763546 c.177A>G synonymous_variant 0.19
rpoC 763550 p.Tyr61Ala missense_variant 0.2
rpoC 763570 c.201G>C synonymous_variant 0.12
rpoC 763578 p.Phe70Tyr missense_variant 0.14
rpoC 763642 c.273G>C synonymous_variant 0.19
rpoC 763657 p.Glu96Asp missense_variant 0.11
rpoC 763660 c.291T>C synonymous_variant 0.12
rpoC 763675 c.306C>G synonymous_variant 0.11
rpoC 763708 c.339G>C synonymous_variant 0.11
rpoC 763713 c.345G>C synonymous_variant 0.12
rpoC 763723 c.354G>C synonymous_variant 0.11
rpoC 763729 c.360G>C synonymous_variant 0.12
rpoC 763732 c.363C>G synonymous_variant 0.12
rpoC 763735 c.366G>C synonymous_variant 0.18
rpoC 763744 c.375G>C synonymous_variant 0.13
rpoC 763751 p.Ile128Val missense_variant 0.2
rpoC 763772 p.Val135Met missense_variant 0.15
rpoC 763781 p.Ser138Glu missense_variant 0.13
rpoC 764566 c.1197C>G synonymous_variant 0.15
rpoC 764573 p.Leu402Ile missense_variant 0.15
rpoC 764578 c.1209C>G synonymous_variant 0.15
rpoC 764581 c.1212T>C synonymous_variant 0.14
rpoC 764582 p.Leu405Met missense_variant 0.14
rpoC 764593 c.1224C>T synonymous_variant 0.29
rpoC 764602 c.1233C>T synonymous_variant 0.35
rpoC 764605 c.1236G>T synonymous_variant 0.42
rpoC 764611 c.1242G>T synonymous_variant 0.42
rpoC 764632 c.1263T>A synonymous_variant 0.43
rpoC 764647 c.1278C>T synonymous_variant 0.41
rpoC 764650 c.1281G>T synonymous_variant 0.42
rpoC 764653 c.1284G>C synonymous_variant 0.42
rpoC 764656 c.1287C>G synonymous_variant 0.41
rpoC 764662 c.1293G>C synonymous_variant 0.39
rpoC 764677 c.1308C>G synonymous_variant 0.35
rpoC 764678 p.Lys437Gln missense_variant 0.32
rpoC 764683 c.1314G>C synonymous_variant 0.32
rpoC 764692 c.1323C>T synonymous_variant 0.32
rpoC 764706 p.Leu446Gln missense_variant 0.28
rpoC 764731 c.1362G>C synonymous_variant 0.22
rpoC 764737 c.1368G>C synonymous_variant 0.16
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776758 p.Asp575Asn missense_variant 0.22
mmpL5 776984 c.1496delT frameshift_variant 0.15
mmpL5 777482 c.999G>A synonymous_variant 0.22
mmpR5 778448 c.-542G>A upstream_gene_variant 0.33
mmpR5 779247 c.262delG frameshift_variant 0.12
mmpS5 779679 c.-774G>A upstream_gene_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781490 c.-70C>T upstream_gene_variant 0.13
rplC 800753 c.-56C>A upstream_gene_variant 0.25
fbiC 1303016 p.Val29Gly missense_variant 0.33
Rv1258c 1406102 c.1239G>A synonymous_variant 0.15
Rv1258c 1407224 c.116delG frameshift_variant 0.2
embR 1417314 p.Asp12His missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471740 n.-106A>G upstream_gene_variant 0.22
rrs 1471762 n.-84C>T upstream_gene_variant 0.33
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.67
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.71
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.89
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.82
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.88
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.82
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.98
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.82
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.8
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.18
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.67
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.85
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.82
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 1.0
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 1.0
rrs 1472290 n.445C>T non_coding_transcript_exon_variant 1.0
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 1.0
rrs 1472295 n.450A>C non_coding_transcript_exon_variant 1.0
rrs 1472298 n.453_454insCCTGC non_coding_transcript_exon_variant 1.0
rrs 1472314 n.469A>G non_coding_transcript_exon_variant 1.0
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 1.0
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 1.0
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 1.0
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 1.0
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 1.0
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.67
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.33
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.33
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.33
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.5
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.33
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.33
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.33
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.5
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.25
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.25
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.18
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.71
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 1.0
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.93
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 1.0
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 1.0
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.82
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.92
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.84
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.95
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 1.0
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 1.0
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 1.0
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.11
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.81
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.11
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 1.0
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.92
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.89
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 1.0
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.79
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.78
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.97
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.97
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.97
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.95
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.64
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.64
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.95
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.86
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.94
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.86
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.95
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.95
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.95
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.26
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.85
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.67
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.63
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.9
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.9
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.73
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.81
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.85
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.74
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.72
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.21
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.93
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.7
rrs 1473283 n.1438T>C non_coding_transcript_exon_variant 0.19
rrs 1473284 n.1439A>T non_coding_transcript_exon_variant 0.19
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.7
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.92
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.19
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.19
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.93
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.19
rrl 1473384 n.-274A>G upstream_gene_variant 0.6
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.8
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.75
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.8
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.8
rrl 1474387 n.730C>T non_coding_transcript_exon_variant 0.75
rrl 1474393 n.736A>G non_coding_transcript_exon_variant 0.67
rrl 1474402 n.745T>C non_coding_transcript_exon_variant 0.67
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 1.0
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.75
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.83
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.83
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.86
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.86
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.8
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.8
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.8
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.8
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.8
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 0.5
rrl 1475754 n.2097G>A non_coding_transcript_exon_variant 0.5
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.5
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.5
rrl 1475774 n.2117C>T non_coding_transcript_exon_variant 0.5
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.5
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.13
rrl 1475866 n.2209T>A non_coding_transcript_exon_variant 0.15
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.71
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 1.0
rrl 1475892 n.2235A>G non_coding_transcript_exon_variant 0.29
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.29
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.4
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 1.0
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.67
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.4
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 1.0
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.69
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.86
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 1.0
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.83
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 1.0
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 1.0
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.67
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.33
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.83
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.83
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 1.0
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.33
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.67
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.67
inhA 1673816 c.-386G>A upstream_gene_variant 1.0
rpsA 1834195 c.654G>C synonymous_variant 0.2
rpsA 1834228 c.687C>T synonymous_variant 0.31
rpsA 1834234 c.693G>C synonymous_variant 0.33
rpsA 1834240 c.699T>C synonymous_variant 0.3
rpsA 1834246 c.705G>T synonymous_variant 0.38
rpsA 1834249 c.708T>C synonymous_variant 0.43
rpsA 1834261 c.720A>G synonymous_variant 0.53
rpsA 1834264 c.723G>C synonymous_variant 0.56
rpsA 1834294 c.753G>C synonymous_variant 0.78
rpsA 1834298 p.Gln253Glu missense_variant 0.74
rpsA 1834306 c.765T>C synonymous_variant 0.74
rpsA 1834307 p.Asp256Gln missense_variant 0.74
rpsA 1834312 c.771G>A synonymous_variant 0.74
rpsA 1834327 c.786G>T synonymous_variant 0.7
rpsA 1834345 c.804C>T synonymous_variant 0.55
rpsA 1834348 c.807T>C synonymous_variant 0.55
rpsA 1834354 c.813G>C synonymous_variant 0.48
rpsA 1834357 c.816T>C synonymous_variant 0.45
rpsA 1834360 c.819G>C synonymous_variant 0.45
rpsA 1834361 c.820T>C synonymous_variant 0.45
rpsA 1834366 c.825A>G synonymous_variant 0.45
rpsA 1834375 c.834G>C synonymous_variant 0.43
rpsA 1834378 c.837T>G synonymous_variant 0.43
rpsA 1834387 c.846C>T synonymous_variant 0.38
rpsA 1834394 c.853_854insA frameshift_variant 0.26
rpsA 1834398 c.858delC frameshift_variant 0.22
rpsA 1834411 c.870T>C synonymous_variant 0.2
tlyA 1917764 c.-176C>T upstream_gene_variant 0.2
tlyA 1917824 c.-116C>T upstream_gene_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918683 c.744C>T synonymous_variant 0.25
ndh 2102970 p.Gly25Ser missense_variant 0.25
katG 2154146 p.Asp656Asn missense_variant 0.15
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155964 p.Gln50Lys missense_variant 0.12
PPE35 2167745 p.Thr956Arg missense_variant 0.13
PPE35 2167865 c.2748G>C synonymous_variant 0.29
PPE35 2167868 c.2745A>C synonymous_variant 0.25
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168019 p.Thr865Ile missense_variant 1.0
PPE35 2168763 p.Thr617Ile missense_variant 0.25
PPE35 2169269 c.1344A>G synonymous_variant 0.25
PPE35 2169272 c.1341C>G synonymous_variant 0.25
PPE35 2169278 c.1335T>C synonymous_variant 0.2
PPE35 2169281 c.1332T>G synonymous_variant 0.2
PPE35 2169441 p.Ala391Gly missense_variant 0.22
PPE35 2169447 p.Phe389Thr missense_variant 0.22
PPE35 2170472 c.141G>A synonymous_variant 0.22
PPE35 2170574 c.39C>G synonymous_variant 0.12
PPE35 2170577 c.36G>A synonymous_variant 0.12
Rv1979c 2222088 p.Leu359Phe missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
pncA 2289634 c.-393A>G upstream_gene_variant 0.25
kasA 2518864 c.750G>C synonymous_variant 0.13
eis 2714474 p.Thr287Ala missense_variant 0.12
ahpC 2725981 c.-212T>C upstream_gene_variant 0.25
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ahpC 2726758 p.Glu189Val missense_variant 0.29
folC 2747052 p.Ala183Thr missense_variant 0.18
folC 2747158 c.441G>T synonymous_variant 0.14
pepQ 2859660 c.759G>A synonymous_variant 0.29
pepQ 2860252 p.Thr56Ile missense_variant 0.13
ribD 2987537 c.699G>A synonymous_variant 0.11
Rv2752c 3066258 c.-67G>A upstream_gene_variant 0.2
thyX 3067987 c.-42C>T upstream_gene_variant 1.0
thyX 3068093 c.-148A>C upstream_gene_variant 0.29
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3086841 p.Glu8Lys missense_variant 0.2
fbiD 3339468 c.351G>A synonymous_variant 0.2
fbiD 3339498 c.381G>A synonymous_variant 0.2
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474143 p.Trp46Tyr missense_variant 0.17
fprA 3474459 c.453A>C synonymous_variant 0.15
fprA 3474790 p.Pro262Ser missense_variant 0.2
rpoA 3877839 c.669G>A synonymous_variant 0.12
clpC1 4038440 c.2265C>A synonymous_variant 0.18
clpC1 4039049 c.1656C>T synonymous_variant 0.22
clpC1 4039774 p.Lys311Glu missense_variant 0.4
clpC1 4039827 p.Val293Asp missense_variant 0.29
embC 4239964 c.102G>A synonymous_variant 0.22
embC 4240235 p.Arg125Trp missense_variant 0.17
embC 4240571 p.Gly237Trp missense_variant 0.17
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242454 c.-779G>A upstream_gene_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4246200 p.Gln990* stop_gained 0.2
embB 4246536 p.Arg8His missense_variant 0.14
embB 4246585 c.72C>T synonymous_variant 0.18
embB 4248963 p.Ala817Val missense_variant 0.5
embB 4249323 p.Ala937Glu missense_variant 0.22
aftB 4268198 c.639C>T synonymous_variant 0.15
ethA 4326582 p.Asn298Asp missense_variant 0.14
ethA 4327364 p.Lys37Thr missense_variant 0.15
ethA 4328318 c.-845G>A upstream_gene_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338719 c.-198T>C upstream_gene_variant 0.12
gid 4407588 c.615A>G synonymous_variant 1.0