TB-Profiler result

Run: SRR3742667
Summary

Run ID: SRR3742667

Sample name:

Date: 04-04-2023 05:39:55

Number of reads: 24260

Percentage reads mapped: 0.27

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoB 762878 p.Ile1024Met missense_variant 1.0
rpoB 762879 p.Met1025Leu missense_variant 1.0
rpoB 762909 p.Ile1035Leu missense_variant 1.0
rpoC 762917 c.-453C>G upstream_gene_variant 1.0
rpoC 762920 c.-450C>G upstream_gene_variant 1.0
rpoC 762923 c.-447C>G upstream_gene_variant 1.0
rpoC 762929 c.-441G>T upstream_gene_variant 1.0
rpoB 762939 p.Met1045Leu missense_variant 1.0
rpoB 762942 p.Ile1046Val missense_variant 1.0
rpoC 762953 c.-417G>A upstream_gene_variant 1.0
rpoC 762965 c.-405T>C upstream_gene_variant 1.0
rpoC 762989 c.-381G>T upstream_gene_variant 1.0
rpoB 762990 p.Phe1062Leu missense_variant 1.0
rpoC 762995 c.-375G>C upstream_gene_variant 1.0
rpoB 763005 p.Cys1067Val missense_variant 1.0
rpoC 763013 c.-357C>T upstream_gene_variant 1.0
rpoB 763014 p.Met1070Leu missense_variant 1.0
rpoB 763017 p.Gln1071Glu missense_variant 1.0
rpoC 763028 c.-342T>C upstream_gene_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763050 p.Leu1082Met missense_variant 1.0
rpoC 763053 c.-317T>C upstream_gene_variant 1.0
rpoC 764377 c.1008C>G synonymous_variant 1.0
rpoC 764383 c.1014C>G synonymous_variant 1.0
rpoC 764387 c.1018T>C synonymous_variant 1.0
rpoC 764398 c.1029G>C synonymous_variant 1.0
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 1.0
rpoC 764419 c.1050C>G synonymous_variant 1.0
rpoC 764446 p.Asp359Glu missense_variant 1.0
rpoC 764450 p.Gly361Arg missense_variant 1.0
rpoC 764461 p.Glu364Asp missense_variant 1.0
rpoC 764566 c.1197C>G synonymous_variant 1.0
rpoC 764575 c.1206T>G synonymous_variant 1.0
rpoC 764578 c.1209C>G synonymous_variant 1.0
rpoC 764581 c.1212T>C synonymous_variant 1.0
rpoC 764582 p.Leu405Met missense_variant 1.0
rpoC 764611 c.1242G>T synonymous_variant 1.0
rpoC 764632 c.1263T>C synonymous_variant 1.0
rpoC 764635 c.1266C>G synonymous_variant 1.0
rpoC 764640 p.Tyr424Phe missense_variant 1.0
rpoC 764650 c.1281G>C synonymous_variant 1.0
rpoC 764663 p.Val432Thr missense_variant 1.0
rpoC 764668 c.1299C>G synonymous_variant 1.0
rpoC 764672 p.Gln435Glu missense_variant 1.0
rpoC 764677 c.1308C>G synonymous_variant 1.0
rpoC 764695 c.1326T>C synonymous_variant 1.0
rpoC 764701 c.1332C>G synonymous_variant 1.0
rpoC 764705 p.Leu446Lys missense_variant 1.0
rrs 1471876 n.31G>A non_coding_transcript_exon_variant 1.0
rrs 1471878 n.33C>T non_coding_transcript_exon_variant 1.0
rrs 1471892 n.47G>A non_coding_transcript_exon_variant 1.0
rrs 1472101 n.256G>A non_coding_transcript_exon_variant 0.75
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.8
rrs 1472108 n.263C>A non_coding_transcript_exon_variant 0.88
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 1.0
rrs 1472128 n.283G>C non_coding_transcript_exon_variant 1.0
rrs 1472129 n.284G>T non_coding_transcript_exon_variant 1.0
rrs 1472135 n.290C>G non_coding_transcript_exon_variant 0.92
rrs 1472138 n.293C>T non_coding_transcript_exon_variant 0.92
rrs 1472147 n.302G>A non_coding_transcript_exon_variant 0.92
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.92
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.92
rrs 1472153 n.308G>C non_coding_transcript_exon_variant 0.92
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.94
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.54
rrs 1472213 n.368G>A non_coding_transcript_exon_variant 0.7
rrs 1472214 n.369C>G non_coding_transcript_exon_variant 0.9
rrs 1472235 n.390G>C non_coding_transcript_exon_variant 0.89
rrs 1472236 n.391C>T non_coding_transcript_exon_variant 0.78
rrs 1472240 n.395G>C non_coding_transcript_exon_variant 1.0
rrs 1472242 n.397C>T non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472252 n.407G>T non_coding_transcript_exon_variant 1.0
rrs 1472253 n.408G>C non_coding_transcript_exon_variant 1.0
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 1.0
rrs 1472266 n.421C>A non_coding_transcript_exon_variant 1.0
rrs 1472277 n.432C>G non_coding_transcript_exon_variant 1.0
rrs 1472278 n.433C>A non_coding_transcript_exon_variant 1.0
rrs 1472338 n.493A>C non_coding_transcript_exon_variant 0.89
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472349 n.504A>C non_coding_transcript_exon_variant 1.0
rrs 1472374 n.529T>G non_coding_transcript_exon_variant 1.0
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.75
rrs 1472382 n.537G>T non_coding_transcript_exon_variant 0.73
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 1.0
rrs 1472391 n.546C>T non_coding_transcript_exon_variant 1.0
rrs 1472412 n.567A>C non_coding_transcript_exon_variant 1.0
rrs 1472415 n.570T>A non_coding_transcript_exon_variant 1.0
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 1.0
rrs 1472544 n.699C>T non_coding_transcript_exon_variant 0.9
rrs 1472545 n.700A>C non_coding_transcript_exon_variant 0.9
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.96
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.96
rrs 1472574 n.729T>A non_coding_transcript_exon_variant 0.96
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.96
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.96
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.96
rrs 1472583 n.738T>A non_coding_transcript_exon_variant 0.96
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.96
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.96
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.96
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 1.0
rrs 1472706 n.861C>G non_coding_transcript_exon_variant 0.5
rrs 1472707 n.862A>G non_coding_transcript_exon_variant 0.5
rrs 1472708 n.863T>A non_coding_transcript_exon_variant 0.5
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.33
rrs 1472715 n.870C>G non_coding_transcript_exon_variant 1.0
rrs 1472716 n.871C>A non_coding_transcript_exon_variant 1.0
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.31
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.33
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.67
rrs 1472754 n.909G>T non_coding_transcript_exon_variant 0.32
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 1.0
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 1.0
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.66
rrs 1472812 n.967A>C non_coding_transcript_exon_variant 0.7
rrs 1472827 n.982G>C non_coding_transcript_exon_variant 1.0
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 1.0
rrs 1472887 n.1042G>C non_coding_transcript_exon_variant 1.0
rrs 1472923 n.1078G>C non_coding_transcript_exon_variant 1.0
rrs 1472934 n.1089C>G non_coding_transcript_exon_variant 1.0
rrs 1473044 n.1199C>G non_coding_transcript_exon_variant 1.0
rrs 1473051 n.1206T>C non_coding_transcript_exon_variant 1.0
rrs 1473053 n.1208T>G non_coding_transcript_exon_variant 1.0
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 1.0
rrs 1473130 n.1285G>T non_coding_transcript_exon_variant 1.0
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 1.0
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 1.0
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 1.0
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 1.0
rrs 1473193 n.1348G>T non_coding_transcript_exon_variant 0.73
rrs 1473195 n.1350T>A non_coding_transcript_exon_variant 0.72
rrs 1473248 n.1403G>A non_coding_transcript_exon_variant 1.0
rrs 1473249 n.1404T>C non_coding_transcript_exon_variant 1.0
rrl 1474584 n.927C>G non_coding_transcript_exon_variant 1.0
rrl 1475499 n.1842C>G non_coding_transcript_exon_variant 0.88
rrl 1475522 n.1865A>C non_coding_transcript_exon_variant 0.9
rrl 1475526 n.1869C>T non_coding_transcript_exon_variant 1.0
rrl 1475528 n.1871T>G non_coding_transcript_exon_variant 0.9
rrl 1475538 n.1881T>C non_coding_transcript_exon_variant 1.0
rrl 1475539 n.1882A>T non_coding_transcript_exon_variant 1.0
rrl 1475540 n.1883C>T non_coding_transcript_exon_variant 1.0
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0
rrl 1475550 n.1893A>C non_coding_transcript_exon_variant 1.0
rrl 1475553 n.1896G>C non_coding_transcript_exon_variant 1.0
rrl 1475555 n.1898T>G non_coding_transcript_exon_variant 1.0
rrl 1475564 n.1907C>A non_coding_transcript_exon_variant 1.0
rrl 1475574 n.1917C>G non_coding_transcript_exon_variant 1.0
rrl 1475575 n.1918C>T non_coding_transcript_exon_variant 1.0
rrl 1475576 n.1919C>A non_coding_transcript_exon_variant 1.0
rrl 1475777 n.2120A>C non_coding_transcript_exon_variant 1.0
rrl 1475783 n.2126T>G non_coding_transcript_exon_variant 1.0
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 1.0
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 1.0
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 1.0
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 1.0
rrl 1475876 n.2220_2221delCT non_coding_transcript_exon_variant 1.0
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 1.0
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.83
rrl 1476160 n.2503T>C non_coding_transcript_exon_variant 0.83
rrl 1476164 n.2507A>C non_coding_transcript_exon_variant 0.83
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 0.83
rrl 1476238 n.2581T>C non_coding_transcript_exon_variant 0.9
rrl 1476246 n.2589G>A non_coding_transcript_exon_variant 1.0
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 1.0
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.98
rrl 1476266 n.2609G>A non_coding_transcript_exon_variant 0.99
rrl 1476279 n.2622G>C non_coding_transcript_exon_variant 0.99
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.99
rrl 1476281 n.2624T>A non_coding_transcript_exon_variant 1.0
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.99
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.99
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.99
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.99
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.99
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 1.0
rrl 1476338 n.2681C>T non_coding_transcript_exon_variant 1.0
rrl 1476356 n.2699C>G non_coding_transcript_exon_variant 1.0
rrl 1476357 n.2700T>A non_coding_transcript_exon_variant 1.0
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 1.0
rrl 1476384 n.2727G>C non_coding_transcript_exon_variant 1.0
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 1.0
rrl 1476411 n.2754G>T non_coding_transcript_exon_variant 1.0
rrl 1476442 n.2785T>A non_coding_transcript_exon_variant 0.98
rrl 1476443 n.2786G>T non_coding_transcript_exon_variant 0.98
rrl 1476455 n.2798C>A non_coding_transcript_exon_variant 0.97
rrl 1476456 n.2799A>T non_coding_transcript_exon_variant 0.98
rrl 1476463 n.2806C>A non_coding_transcript_exon_variant 0.99
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 1.0
rrl 1476470 n.2813C>T non_coding_transcript_exon_variant 0.71
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476512 n.2855C>T non_coding_transcript_exon_variant 1.0
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 1.0