TB-Profiler result

Run: ERR2513830
Summary

Run ID: ERR2513830

Sample name:

Date: 31-03-2023 19:55:55

Number of reads: 515925

Percentage reads mapped: 66.13

Strain: lineage4.8

Drug-resistance: RR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.44 rifampicin
rpoB 761196 p.Leu464Met missense_variant 0.11 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 0.96 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.54 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8296 p.Tyr332Ser missense_variant 0.11
rpoB 759974 p.Glu56Asp missense_variant 0.12
rpoB 760325 c.519G>A synonymous_variant 0.11
rpoB 760940 c.1134G>T synonymous_variant 0.14
rpoB 761012 p.Asp402Glu missense_variant 0.12
rpoB 761013 p.Val403Thr missense_variant 0.12
rpoB 761018 p.Glu404Asp missense_variant 0.12
rpoB 761019 p.Ala405Ser missense_variant 0.12
rpoB 761027 c.1221A>G synonymous_variant 0.18
rpoB 761030 c.1224G>C synonymous_variant 0.25
rpoB 761037 c.1231T>C synonymous_variant 0.36
rpoB 761051 c.1245G>C synonymous_variant 0.38
rpoB 761054 c.1248G>C synonymous_variant 0.38
rpoB 761057 c.1251G>C synonymous_variant 0.38
rpoB 761060 c.1254C>G synonymous_variant 0.38
rpoB 761084 c.1278C>A synonymous_variant 0.42
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.42
rpoB 761096 c.1290G>C synonymous_variant 0.38
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.4
rpoB 761102 c.1296A>G synonymous_variant 0.42
rpoB 761132 c.1326G>C synonymous_variant 0.43
rpoB 761133 c.1327T>C synonymous_variant 0.43
rpoB 761150 c.1344A>T synonymous_variant 0.38
rpoB 761159 c.1353G>C synonymous_variant 0.38
rpoB 761165 c.1359G>C synonymous_variant 0.33
rpoB 761180 c.1374A>C synonymous_variant 0.2
rpoB 761186 p.Glu460Asp missense_variant 0.2
rpoB 761189 c.1383T>C synonymous_variant 0.11
rpoB 761192 c.1386C>G synonymous_variant 0.11
rpoB 761195 c.1389G>C synonymous_variant 0.11
rpoB 761201 c.1395G>A synonymous_variant 0.12
rpoB 761204 c.1398C>T synonymous_variant 0.12
rpoB 761207 c.1401C>A synonymous_variant 0.12
rpoB 761213 c.1407G>C synonymous_variant 0.12
rpoB 761219 c.1413G>C synonymous_variant 0.12
rpoC 762452 c.-918G>T upstream_gene_variant 0.11
rpoC 762926 c.-444C>G upstream_gene_variant 0.11
rpoC 762929 c.-441G>C upstream_gene_variant 0.11
rpoC 762947 c.-423C>G upstream_gene_variant 0.12
rpoC 762971 c.-399G>C upstream_gene_variant 0.19
rpoC 762980 c.-390T>C upstream_gene_variant 0.19
rpoB 763317 c.3513delT frameshift_variant 0.13
rpoC 763657 p.Glu96Asp missense_variant 0.13
rpoC 763666 c.297G>C synonymous_variant 0.19
rpoC 763675 c.306C>G synonymous_variant 0.12
rpoC 763699 c.330G>T synonymous_variant 0.17
rpoC 763708 c.339G>C synonymous_variant 0.12
rpoC 763714 c.345G>C synonymous_variant 0.18
rpoC 763717 c.348T>C synonymous_variant 0.13
rpoC 763718 p.Leu117Val missense_variant 0.13
rpoC 763723 c.354G>C synonymous_variant 0.13
rpoC 763724 p.Asp119Asn missense_variant 0.13
rpoC 763729 c.360G>C synonymous_variant 0.13
rpoC 763744 c.375G>C synonymous_variant 0.17
rpoC 763751 p.Ile128Val missense_variant 0.16
rpoC 763772 p.Val135Met missense_variant 0.15
rpoC 764632 c.1263T>C synonymous_variant 0.13
rpoC 764650 c.1281G>T synonymous_variant 0.12
rpoC 764662 c.1293G>C synonymous_variant 0.13
rpoC 764706 p.Leu446Gln missense_variant 0.14
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpS5 778790 p.Val39Ala missense_variant 0.11
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303670 p.Asp247Gly missense_variant 0.13
fbiC 1304688 c.1758C>T synonymous_variant 0.12
Rv1258c 1406471 c.870C>T synonymous_variant 0.12
Rv1258c 1406663 c.678C>T synonymous_variant 0.13
embR 1416534 p.Gly272Ser missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.25
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.53
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.53
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.74
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.68
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.74
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.74
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.8
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.78
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.74
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.82
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.88
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.45
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.45
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 1.0
rrs 1472498 n.653C>A non_coding_transcript_exon_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.8
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.21
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.75
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.75
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.75
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.75
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.77
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.77
rrs 1472549 n.704G>A non_coding_transcript_exon_variant 0.21
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.72
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.79
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.54
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.74
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.23
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 1.0
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.22
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.78
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.78
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.67
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.37
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 1.0
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 1.0
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.57
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.43
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.57
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.34
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 0.95
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.93
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.9
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.83
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.38
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.56
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.35
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.55
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.44
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.57
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.54
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.52
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.52
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.53
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.47
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.5
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 1.0
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.25
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.5
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 1.0
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.67
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.89
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.8
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.15
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.91
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.83
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.22
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.23
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.91
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.63
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.64
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.97
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.98
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.96
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.78
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.79
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.94
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.87
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.95
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.21
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.67
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.93
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.93
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.93
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.9
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.84
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.75
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.92
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.9
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.78
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.78
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.71
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.78
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.84
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.85
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.73
rrs 1473293 n.1449delA non_coding_transcript_exon_variant 0.67
rrs 1473293 n.1449A>G non_coding_transcript_exon_variant 0.52
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.7
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.85
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.87
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.14
rrl 1473384 n.-274A>G upstream_gene_variant 0.53
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 1.0
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 1.0
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 1.0
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.5
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.5
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.5
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.5
rrl 1474497 n.840G>T non_coding_transcript_exon_variant 0.43
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.57
rrl 1474503 n.846G>A non_coding_transcript_exon_variant 0.43
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.57
rrl 1474506 n.849C>A non_coding_transcript_exon_variant 0.5
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.5
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.57
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.43
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.29
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.29
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.29
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.29
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.29
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.29
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.8
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.8
rrl 1474634 n.977T>G non_coding_transcript_exon_variant 0.8
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 0.8
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 1.0
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.4
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.6
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.88
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.25
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 1.0
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 1.0
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 1.0
rrl 1475764 n.2107A>G non_coding_transcript_exon_variant 1.0
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 1.0
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 1.0
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.4
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.67
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.67
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.4
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.6
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.6
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.4
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.4
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.5
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 1.0
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.67
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 0.67
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.67
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.67
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.5
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.5
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.5
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.75
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.94
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.95
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.84
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.84
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.94
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.65
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.85
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.81
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.76
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.18
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.31
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.62
rrl 1476524 n.2867C>T non_coding_transcript_exon_variant 0.73
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.82
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.22
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 0.11
rrl 1476531 n.2874T>C non_coding_transcript_exon_variant 0.11
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.65
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.11
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.72
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.72
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.56
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.17
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.27
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.15
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.38
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.38
fabG1 1673350 c.-90T>A upstream_gene_variant 0.17
rpsA 1833936 p.Glu132Gly missense_variant 0.11
rpsA 1834294 c.753G>C synonymous_variant 0.19
rpsA 1834298 p.Gln253Glu missense_variant 0.19
rpsA 1834303 c.762T>C synonymous_variant 0.11
rpsA 1834306 c.765T>C synonymous_variant 0.19
rpsA 1834307 p.Asp256Gln missense_variant 0.19
rpsA 1834327 c.786G>T synonymous_variant 0.21
rpsA 1834345 c.804C>T synonymous_variant 0.16
rpsA 1834348 c.807T>C synonymous_variant 0.17
rpsA 1834354 c.813G>C synonymous_variant 0.16
rpsA 1834357 c.816T>C synonymous_variant 0.13
rpsA 1834360 c.819G>C synonymous_variant 0.13
rpsA 1834361 c.820T>C synonymous_variant 0.16
rpsA 1834366 c.825A>G synonymous_variant 0.14
rpsA 1834375 c.834G>C synonymous_variant 0.19
rpsA 1834378 c.837T>C synonymous_variant 0.18
rpsA 1834387 c.846C>T synonymous_variant 0.17
rpsA 1834411 c.870T>C synonymous_variant 0.16
rpsA 1834417 c.876G>C synonymous_variant 0.13
rpsA 1834427 p.Ile296Val missense_variant 0.12
rpsA 1834435 c.894G>C synonymous_variant 0.12
rpsA 1834451 c.910T>C synonymous_variant 0.12
tlyA 1917972 c.33A>G synonymous_variant 0.91
ndh 2101876 c.1167C>A synonymous_variant 0.11
ndh 2102367 p.Ala226Pro missense_variant 0.12
ndh 2102368 c.675C>T synonymous_variant 0.12
ndh 2102860 c.183G>A synonymous_variant 0.15
katG 2154910 p.Pro401Leu missense_variant 0.12
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289808 c.-567C>T upstream_gene_variant 1.0
kasA 2519119 c.1008_1009dupGT frameshift_variant 0.33
ahpC 2726395 p.Phe68Ser missense_variant 0.11
Rv2752c 3065756 p.Val146Ile missense_variant 0.15
ald 3086796 c.-24C>T upstream_gene_variant 1.0
fbiD 3339404 p.Ile96Thr missense_variant 0.22
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
alr 3841506 c.-86A>C upstream_gene_variant 0.22
clpC1 4038838 p.Leu623Met missense_variant 0.12
clpC1 4039921 p.Arg262Ser missense_variant 0.13
clpC1 4040315 c.390G>A synonymous_variant 0.12
clpC1 4040318 c.387C>T synonymous_variant 0.12
clpC1 4040324 c.381G>C synonymous_variant 0.12
clpC1 4040336 c.369G>C synonymous_variant 0.11
clpC1 4040342 c.363C>T synonymous_variant 0.11
clpC1 4040345 c.360C>G synonymous_variant 0.11
clpC1 4040348 c.357G>T synonymous_variant 0.12
clpC1 4040351 c.354C>G synonymous_variant 0.12
clpC1 4040354 c.351A>G synonymous_variant 0.12
clpC1 4040363 c.342A>C synonymous_variant 0.11
clpC1 4040369 c.336C>G synonymous_variant 0.11
clpC1 4040380 c.325T>C synonymous_variant 0.11
clpC1 4040381 c.324T>C synonymous_variant 0.11
panD 4044281 c.1A>G start_lost 0.12
embC 4239973 c.111T>G synonymous_variant 0.3
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4267760 c.1077C>T synonymous_variant 0.14
ubiA 4269029 p.Gly269Ser missense_variant 0.13
ethA 4326186 p.Pro430Thr missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408252 c.-50A>G upstream_gene_variant 0.2
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0