TB-Profiler result

Run: SRR5818428
Summary

Run ID: SRR5818428

Sample name:

Date: 04-04-2023 11:27:15

Number of reads: 534773

Percentage reads mapped: 98.13

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
rrs 1471940 n.95G>A non_coding_transcript_exon_variant 0.19
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.24
rrs 1472151 n.306C>A non_coding_transcript_exon_variant 0.31
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.38
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.37
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.24
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.5
rrs 1472282 n.437T>G non_coding_transcript_exon_variant 0.17
rrs 1472284 n.439C>T non_coding_transcript_exon_variant 0.17
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.27
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.23
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.27
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.27
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.19
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.28
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.27
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.24
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.24
rrs 1472330 n.485G>T non_coding_transcript_exon_variant 0.23
rrs 1472332 n.487A>G non_coding_transcript_exon_variant 0.19
rrs 1472333 n.488G>A non_coding_transcript_exon_variant 0.19
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.2
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.51
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.14
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.19
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.24
rrs 1472422 n.577T>C non_coding_transcript_exon_variant 0.14
rrs 1472435 n.590T>C non_coding_transcript_exon_variant 0.66
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 0.65
rrs 1472439 n.594C>T non_coding_transcript_exon_variant 0.53
rrs 1472447 n.602C>T non_coding_transcript_exon_variant 0.53
rrs 1472448 n.603T>C non_coding_transcript_exon_variant 0.65
rrs 1472449 n.604C>T non_coding_transcript_exon_variant 0.24
rrs 1472450 n.605A>G non_coding_transcript_exon_variant 0.61
rrs 1472451 n.606C>G non_coding_transcript_exon_variant 0.62
rrs 1472461 n.616G>C non_coding_transcript_exon_variant 0.55
rrs 1472462 n.617T>C non_coding_transcript_exon_variant 0.63
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 0.72
rrs 1472471 n.626G>A non_coding_transcript_exon_variant 0.58
rrs 1472476 n.631A>G non_coding_transcript_exon_variant 0.14
rrs 1472489 n.644A>T non_coding_transcript_exon_variant 0.66
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.78
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.17
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.79
rrs 1472504 n.659A>T non_coding_transcript_exon_variant 0.2
rrs 1472505 n.660G>A non_coding_transcript_exon_variant 0.2
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.16
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.13
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.15
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.17
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.15
rrl 1476535 n.2878G>A non_coding_transcript_exon_variant 0.16
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.17
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.17
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 0.13
rrl 1476624 n.2967T>A non_coding_transcript_exon_variant 0.19
inhA 1674896 p.Met232Thr missense_variant 0.67
tlyA 1917972 c.33A>G synonymous_variant 1.0
pncA 2288942 c.300C>G synonymous_variant 0.15
ahpC 2726184 c.-9A>C upstream_gene_variant 0.36
embB 4247646 p.Glu378Ala missense_variant 0.45
ethA 4326148 c.1326G>T synonymous_variant 0.27
ethA 4326388 c.1086C>T synonymous_variant 0.25
ethA 4326439 p.Asn345Lys missense_variant 0.25
ethA 4326764 p.Ala237Val missense_variant 0.23
gid 4407588 c.615A>G synonymous_variant 0.9
gid 4407742 p.Arg154Pro missense_variant 0.53
gid 4407873 c.330G>T synonymous_variant 0.53