TB-Profiler result

Run: ERR4817131
Summary

Run ID: ERR4817131

Sample name:

Date: 01-04-2023 14:49:15

Number of reads: 202983

Percentage reads mapped: 47.61

Strain:

Drug-resistance: Pre-XDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrA 7572 p.Ser91Ala missense_variant 0.29 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
rpoB 761127 p.Ser441Ala missense_variant 0.3 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.59 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7547 c.246C>T synonymous_variant 0.25
gyrA 7559 c.258G>C synonymous_variant 0.25
gyrA 7571 c.270G>T synonymous_variant 0.25
gyrA 7584 p.Ser95Ala missense_variant 0.29
gyrA 7589 c.288G>C synonymous_variant 0.29
gyrA 7591 p.Val97Ala missense_variant 0.29
gyrA 7596 p.Met99Leu missense_variant 0.33
gyrA 7600 p.Ala100Val missense_variant 0.33
gyrA 7625 c.324G>C synonymous_variant 0.33
gyrA 7628 c.327G>C synonymous_variant 0.33
gyrA 7631 c.330G>C synonymous_variant 0.33
gyrA 7633 p.Asp111Ala missense_variant 0.33
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576751 p.Lys468Asn missense_variant 0.29
rpoB 761037 c.1231T>C synonymous_variant 0.29
rpoB 761051 c.1245G>C synonymous_variant 0.38
rpoB 761054 c.1248G>C synonymous_variant 0.38
rpoB 761057 c.1251G>C synonymous_variant 0.29
rpoB 761060 c.1254C>G synonymous_variant 0.38
rpoB 761084 c.1278C>A synonymous_variant 0.33
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.33
rpoB 761096 c.1290G>C synonymous_variant 0.38
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.38
rpoB 761102 c.1296A>G synonymous_variant 0.38
rpoB 761132 c.1326G>C synonymous_variant 0.3
rpoB 761133 c.1327T>C synonymous_variant 0.3
rpoB 761150 c.1344A>C synonymous_variant 0.17
rpoB 761159 c.1353G>C synonymous_variant 0.17
rpoB 761165 c.1359G>C synonymous_variant 0.17
rpoB 761174 c.1368T>C synonymous_variant 0.17
rpoB 762065 c.2259T>C synonymous_variant 0.22
rpoB 762071 p.Asp755Glu missense_variant 0.25
rpoB 762080 c.2274G>C synonymous_variant 0.29
rpoB 762085 p.Ala760Glu missense_variant 0.29
rpoB 762089 c.2283G>A synonymous_variant 0.29
rpoB 762092 c.2286G>A synonymous_variant 0.29
rpoB 762110 c.2304G>C synonymous_variant 0.33
rpoB 762114 p.Ile770Val missense_variant 0.33
rpoB 762122 p.Asp772Glu missense_variant 0.4
rpoB 762125 c.2319G>A synonymous_variant 0.33
rpoB 762126 p.Val774Ser missense_variant 0.33
rpoB 762143 c.2337T>C synonymous_variant 0.33
rpoB 762149 c.2343G>C synonymous_variant 0.33
rpoB 762156 p.Val784Ile missense_variant 0.33
rpoB 762181 p.Asp792Ala missense_variant 0.4
rpoB 762185 c.2379G>C synonymous_variant 0.5
rpoB 762191 c.2385C>T synonymous_variant 0.4
rpoB 762194 c.2388G>C synonymous_variant 0.6
rpoB 762218 c.2412T>C synonymous_variant 0.5
rpoB 762233 c.2427G>C synonymous_variant 0.4
rpoB 762245 c.2439G>C synonymous_variant 0.5
rpoB 762254 c.2448T>C synonymous_variant 0.5
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoB 762879 p.Met1025Leu missense_variant 0.31
rpoC 762887 c.-483G>C upstream_gene_variant 0.15
rpoC 762896 c.-474G>C upstream_gene_variant 0.14
rpoC 762902 c.-468C>T upstream_gene_variant 0.13
rpoC 762911 c.-459C>T upstream_gene_variant 0.12
rpoC 762917 c.-453C>T upstream_gene_variant 0.13
rpoC 762920 c.-450C>T upstream_gene_variant 0.13
rpoC 762929 c.-441G>C upstream_gene_variant 0.15
rpoC 762944 c.-426C>T upstream_gene_variant 0.15
rpoC 762956 c.-414G>T upstream_gene_variant 0.18
rpoC 762962 c.-408C>T upstream_gene_variant 0.2
rpoC 762980 c.-390T>C upstream_gene_variant 0.2
rpoC 762983 c.-387C>T upstream_gene_variant 0.22
rpoC 762989 c.-381G>C upstream_gene_variant 0.22
rpoC 762995 c.-375G>T upstream_gene_variant 0.22
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763578 p.Phe70Tyr missense_variant 0.25
rpoC 763642 c.273G>C synonymous_variant 0.25
rpoC 763648 c.279C>T synonymous_variant 0.33
rpoC 763657 p.Glu96Asp missense_variant 0.33
rpoC 763660 c.291T>G synonymous_variant 0.25
rpoC 763666 c.297G>C synonymous_variant 0.25
rpoC 763675 c.306C>G synonymous_variant 0.22
rpoC 763699 c.330G>T synonymous_variant 0.36
rpoC 763708 c.339G>C synonymous_variant 0.38
rpoC 763714 c.345G>C synonymous_variant 0.36
rpoC 763717 c.348T>C synonymous_variant 0.36
rpoC 763718 p.Leu117Val missense_variant 0.38
rpoC 763723 c.354G>C synonymous_variant 0.33
rpoC 763724 p.Asp119Asn missense_variant 0.36
rpoC 763729 c.360G>C synonymous_variant 0.4
rpoC 763732 c.363C>G synonymous_variant 0.4
rpoC 763735 c.366G>C synonymous_variant 0.44
rpoC 763744 c.375G>C synonymous_variant 0.4
rpoC 763751 p.Ile128Val missense_variant 0.4
rpoC 763772 p.Val135Met missense_variant 0.5
rpoC 764446 p.Asp359Glu missense_variant 0.29
rpoC 764455 c.1086G>C synonymous_variant 0.33
rpoC 764458 c.1089G>C synonymous_variant 0.33
rpoC 764461 c.1092A>G synonymous_variant 0.33
rpoC 764485 c.1116G>C synonymous_variant 0.75
rpoC 764491 c.1122G>T synonymous_variant 0.75
rpoC 764497 c.1128A>G synonymous_variant 0.75
rpoC 764503 c.1134G>T synonymous_variant 0.75
rpoC 764509 c.1140G>C synonymous_variant 0.67
rpoC 764512 c.1143G>C synonymous_variant 0.75
rpoC 764521 c.1152T>C synonymous_variant 0.78
rpoC 764524 c.1155C>T synonymous_variant 0.4
rpoC 764530 c.1161C>T synonymous_variant 0.45
rpoC 764536 c.1167G>C synonymous_variant 0.6
rpoC 764543 p.Thr392Ala missense_variant 0.56
rpoC 764548 c.1179G>T synonymous_variant 0.43
rpoC 764566 c.1197C>G synonymous_variant 0.55
rpoC 764573 p.Leu402Ile missense_variant 0.55
rpoC 764578 c.1209C>G synonymous_variant 0.6
rpoC 764581 c.1212T>C synonymous_variant 0.6
rpoC 764582 p.Leu405Met missense_variant 0.6
rpoC 764602 c.1233C>T synonymous_variant 0.7
rpoC 764605 c.1236G>T synonymous_variant 0.7
rpoC 764611 c.1242G>T synonymous_variant 0.67
rpoC 764632 c.1263T>C synonymous_variant 0.4
rpoC 764647 c.1278C>T synonymous_variant 0.4
rpoC 764650 c.1281G>T synonymous_variant 0.4
rpoC 764653 c.1284G>C synonymous_variant 0.4
rpoC 764656 c.1287C>T synonymous_variant 0.4
rpoC 764662 c.1293G>C synonymous_variant 0.5
rpoC 764677 c.1308C>G synonymous_variant 0.6
rpoC 764678 p.Lys437Gln missense_variant 0.6
rpoC 764706 p.Leu446Gln missense_variant 0.86
rpoC 764713 c.1344G>C synonymous_variant 0.83
rpoC 764731 c.1362G>C synonymous_variant 0.83
rpoC 764737 c.1368G>C synonymous_variant 0.83
rpoC 764746 c.1377G>C synonymous_variant 0.83
rpoC 764752 c.1383G>T synonymous_variant 0.83
rpoC 764755 p.Asp462Glu missense_variant 0.8
rpoC 764756 p.Leu463Lys missense_variant 0.8
rpoC 764762 p.His465Tyr missense_variant 0.8
rpoC 764774 p.Ile469Val missense_variant 0.67
rpoC 764780 p.Ser471Ala missense_variant 0.67
rpoC 764793 p.Met475Lys missense_variant 0.67
rpoC 764797 c.1428G>C synonymous_variant 0.67
rpoC 764813 p.Gln482Glu missense_variant 0.6
rpoC 764824 c.1455T>C synonymous_variant 0.5
rpoC 764827 c.1458G>C synonymous_variant 0.33
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776829 p.His551Pro missense_variant 0.25
mmpL5 777156 p.Arg442Gln missense_variant 0.25
mmpL5 777226 p.Asn419Tyr missense_variant 0.33
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406613 p.Glu243Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.3
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.5
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.55
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.15
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.8
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.14
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.12
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.81
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.82
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.83
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.98
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.78
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.66
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.23
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.65
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.47
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.67
rrs 1472279 n.434T>G non_coding_transcript_exon_variant 0.17
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.67
rrs 1472289 n.444T>G non_coding_transcript_exon_variant 0.67
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.67
rrs 1472295 n.451_466delAGGTCCGGGTTCTCTC non_coding_transcript_exon_variant 1.0
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.67
rrs 1472325 n.480G>C non_coding_transcript_exon_variant 0.67
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.67
rrs 1472338 n.493A>C non_coding_transcript_exon_variant 0.67
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.67
rrs 1472379 n.534T>G non_coding_transcript_exon_variant 0.4
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.4
rrs 1472389 n.544G>A non_coding_transcript_exon_variant 0.4
rrs 1472498 n.653C>A non_coding_transcript_exon_variant 0.83
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.88
rrs 1472513 n.668T>C non_coding_transcript_exon_variant 0.12
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.72
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.74
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.73
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.76
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.8
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.78
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.85
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.85
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.85
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.98
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.85
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.82
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.2
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.23
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.91
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.86
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.56
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.42
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.61
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.64
rrs 1472686 n.841G>T non_coding_transcript_exon_variant 0.22
rrs 1472687 n.842_843insC non_coding_transcript_exon_variant 0.94
rrs 1472687 n.843dupT non_coding_transcript_exon_variant 0.94
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.88
rrs 1472690 n.845C>T non_coding_transcript_exon_variant 0.76
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.33
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.56
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.22
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.62
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.38
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.57
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.57
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.57
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.58
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.49
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.46
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.43
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.89
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.2
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.38
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.97
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.36
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.41
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.36
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.9
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.79
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.16
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.94
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.96
rrs 1472974 n.1129A>G non_coding_transcript_exon_variant 0.17
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.38
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.16
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.34
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.93
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.39
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.42
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.93
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.89
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.92
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.91
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.48
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.64
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.96
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.95
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.97
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.86
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.97
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.95
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.97
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.32
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.93
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.75
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.15
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.61
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.95
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.15
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.14
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.95
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.75
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.75
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.8
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.9
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.89
rrs 1473262 n.1417T>C non_coding_transcript_exon_variant 0.15
rrs 1473270 n.1425G>C non_coding_transcript_exon_variant 0.13
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.95
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.76
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.94
rrs 1473314 n.1469A>G non_coding_transcript_exon_variant 0.12
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.94
rrl 1473384 n.-274A>G upstream_gene_variant 0.82
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 0.67
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.89
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.88
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.64
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.73
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.8
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.88
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.36
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.36
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.5
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.62
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.5
rrl 1474285 n.630_631delTC non_coding_transcript_exon_variant 0.67
rrl 1474294 n.637C>T non_coding_transcript_exon_variant 0.67
rrl 1474295 n.638C>T non_coding_transcript_exon_variant 0.67
rrl 1474296 n.640_650delCTCCGGAGGAG non_coding_transcript_exon_variant 0.67
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.57
rrl 1474326 n.669T>A non_coding_transcript_exon_variant 0.71
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.62
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.71
rrl 1474353 n.696A>G non_coding_transcript_exon_variant 0.75
rrl 1474355 n.698A>G non_coding_transcript_exon_variant 0.62
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.75
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.33
rrl 1474466 n.809G>A non_coding_transcript_exon_variant 0.4
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 0.4
rrl 1474487 n.830G>T non_coding_transcript_exon_variant 0.25
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.62
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.88
rrl 1474496 n.839C>G non_coding_transcript_exon_variant 0.25
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.25
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.88
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.86
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.29
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.29
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.86
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.57
rrl 1474517 n.860C>G non_coding_transcript_exon_variant 0.29
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.5
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.5
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.75
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.5
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.5
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.22
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.17
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.83
rrl 1474637 n.980C>G non_coding_transcript_exon_variant 0.75
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.75
rrl 1474643 n.986A>G non_coding_transcript_exon_variant 0.83
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.88
rrl 1474672 n.1015C>T non_coding_transcript_exon_variant 0.88
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 1.0
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 1.0
rrl 1474687 n.1030C>T non_coding_transcript_exon_variant 0.2
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.8
rrl 1474706 n.1049G>A non_coding_transcript_exon_variant 0.62
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>A non_coding_transcript_exon_variant 1.0
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 1.0
rrl 1474832 n.1175A>T non_coding_transcript_exon_variant 0.81
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.93
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.83
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.8
rrl 1475187 n.1530C>T non_coding_transcript_exon_variant 1.0
rrl 1475188 n.1531C>G non_coding_transcript_exon_variant 1.0
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.67
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.5
rrl 1475751 n.2094C>T non_coding_transcript_exon_variant 1.0
rrl 1475752 n.2095C>T non_coding_transcript_exon_variant 0.75
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.75
rrl 1475758 n.2101A>G non_coding_transcript_exon_variant 0.75
rrl 1475760 n.2103C>T non_coding_transcript_exon_variant 0.75
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 1.0
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 1.0
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 1.0
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 1.0
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.75
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.75
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.4
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.2
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.36
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.18
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.27
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.89
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.78
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.22
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.22
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.67
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.67
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 0.4
rrl 1476164 n.2507A>T non_coding_transcript_exon_variant 0.4
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.4
rrl 1476194 n.2537A>T non_coding_transcript_exon_variant 0.5
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.67
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.67
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.67
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.25
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.57
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.29
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.29
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.71
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.71
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.29
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476263 n.2606C>A non_coding_transcript_exon_variant 0.29
rrl 1476267 n.2610G>T non_coding_transcript_exon_variant 0.57
rrl 1476276 n.2619C>A non_coding_transcript_exon_variant 0.5
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.33
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.67
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.5
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476297 n.2640C>G non_coding_transcript_exon_variant 0.67
rrl 1476298 n.2641C>G non_coding_transcript_exon_variant 0.5
rrl 1476300 n.2643G>T non_coding_transcript_exon_variant 0.75
rrl 1476301 n.2644A>T non_coding_transcript_exon_variant 1.0
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.5
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.5
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.23
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.97
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.99
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.9
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.69
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.86
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.95
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.74
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.86
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.73
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.64
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.18
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.17
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.7
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.55
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.82
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.82
rrl 1476542 n.2885T>C non_coding_transcript_exon_variant 0.18
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.25
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.2
rrl 1476580 n.2923G>A non_coding_transcript_exon_variant 0.2
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.29
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.29
rpsA 1833668 p.Ile43Val missense_variant 0.29
rpsA 1833676 c.135A>G synonymous_variant 0.2
rpsA 1833685 c.144G>C synonymous_variant 0.25
rpsA 1833694 c.153G>C synonymous_variant 0.25
rpsA 1834195 c.654G>C synonymous_variant 0.33
rpsA 1834201 c.660C>T synonymous_variant 0.29
rpsA 1834207 c.666C>T synonymous_variant 0.29
rpsA 1834210 c.669C>T synonymous_variant 0.29
rpsA 1834213 c.672G>C synonymous_variant 0.29
rpsA 1834219 c.678C>T synonymous_variant 0.29
rpsA 1834222 c.681T>C synonymous_variant 0.29
rpsA 1834228 c.687C>T synonymous_variant 0.29
rpsA 1834231 c.690T>G synonymous_variant 0.29
rpsA 1834234 c.693G>C synonymous_variant 0.33
rpsA 1834240 c.699T>C synonymous_variant 0.33
rpsA 1834246 c.705G>T synonymous_variant 0.4
rpsA 1834249 c.708T>C synonymous_variant 0.4
rpsA 1834258 c.717G>A synonymous_variant 0.33
rpsA 1834261 c.720A>G synonymous_variant 0.58
rpsA 1834264 c.723G>C synonymous_variant 0.45
rpsA 1834285 c.744G>C synonymous_variant 0.12
rpsA 1834288 c.747C>A synonymous_variant 0.12
rpsA 1834294 c.753G>C synonymous_variant 0.5
rpsA 1834298 p.Gln253Glu missense_variant 0.5
rpsA 1834306 c.765T>C synonymous_variant 0.36
rpsA 1834307 p.Asp256Gln missense_variant 0.43
rpsA 1834312 c.771G>A synonymous_variant 0.43
rpsA 1834327 c.786G>T synonymous_variant 0.23
rpsA 1834345 c.804C>T synonymous_variant 0.17
rpsA 1834348 c.807T>C synonymous_variant 0.18
rpsA 1834354 c.813G>C synonymous_variant 0.22
rpsA 1834357 c.816T>C synonymous_variant 0.22
rpsA 1834360 c.819G>C synonymous_variant 0.2
rpsA 1834361 c.820T>C synonymous_variant 0.2
rpsA 1834375 c.834G>C synonymous_variant 0.18
rpsA 1834378 c.837T>C synonymous_variant 0.18
rpsA 1834387 c.846C>T synonymous_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155144 p.Asn323Ser missense_variant 0.2
Rv1979c 2222732 c.432delT frameshift_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.33
pepQ 2860260 c.159G>T synonymous_variant 0.29
Rv2752c 3065764 p.Tyr143Phe missense_variant 0.33
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339273 c.156T>G synonymous_variant 0.2
Rv3083 3449182 p.Ser227Thr missense_variant 0.4
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474303 c.297C>T synonymous_variant 0.33
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242959 c.-274C>T upstream_gene_variant 0.25
embA 4245090 p.Gly620Cys missense_variant 0.33
embB 4249195 c.2682C>A synonymous_variant 1.0
aftB 4268129 c.708T>C synonymous_variant 0.17
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4408175 p.Ala10Pro missense_variant 1.0