TB-Profiler

Lineage	Family	RDs	Frequency
lineage4	Euro-American	None	0.99
lineage4.9	Euro-American (H37Rv-like)	None	0.99

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence	Comment
rrs	1472307	n.462C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance	Mutation from literature

Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance

Gene	Chromosome position	Mutation	Type	Estimated fraction	Drugs	Confidence
rpoB	763070	c.3264T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763085	c.3279C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763115	c.3309T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoB	763136	c.3330C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763546	c.177A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763570	c.201G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763573	c.204G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	763603	c.234C>T	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766861	c.3492G>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766864	c.3495G>C	synonymous_variant	1.0	rifampicin
rpoC	766867	c.3498C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	766885	c.3516G>A	synonymous_variant	1.0	rifampicin
rpoC	766894	c.3525T>C	synonymous_variant	1.0	rifampicin
rpoC	766900	c.3531T>C	synonymous_variant	1.0	rifampicin
rpoC	767119	c.3750A>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767134	c.3765C>A	synonymous_variant	1.0	rifampicin
rpoC	767158	c.3789T>C	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpoC	767180	p.Ala1271Gln	missense_variant	1.0	rifampicin
rpoC	767191	c.3822C>G	synonymous_variant	1.0	rifampicin	Not assoc w R - Interim
rpsL	781700	c.141G>C	synonymous_variant	1.0	streptomycin
rpsL	781703	c.144G>T	synonymous_variant	1.0	streptomycin
rpsL	781715	c.156T>C	synonymous_variant	1.0	streptomycin
rpsL	781728	c.169T>C	synonymous_variant	1.0	streptomycin
rpsL	781736	c.177T>C	synonymous_variant	1.0	streptomycin
rpsL	781742	c.183C>T	synonymous_variant	1.0	streptomycin
rpsL	781748	c.189C>G	synonymous_variant	1.0	streptomycin
rpsL	781754	c.195G>C	synonymous_variant	1.0	streptomycin
rpsL	781760	c.201T>C	synonymous_variant	1.0	streptomycin
rpsL	781772	c.213C>A	synonymous_variant	1.0	streptomycin
rrs	1472061	n.216A>T	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472075	n.230A>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472108	n.263C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472300	n.455C>T	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1472969	n.1124A>G	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472970	n.1125C>G	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472977	n.1132G>C	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1472978	n.1133T>C	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473105	n.1260G>A	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473123	n.1278delAinsTT	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin
					capreomycin
					amikacin
rrs	1473145	n.1300C>T	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473166	n.1321G>A	non_coding_transcript_exon_variant	1.0	streptomycin	Uncertain significance
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrs	1473290	n.1445C>T	non_coding_transcript_exon_variant	1.0	streptomycin
					kanamycin	Uncertain significance
					capreomycin	Uncertain significance
					amikacin	Uncertain significance
rrl	1473417	n.-241C>T	upstream_gene_variant	0.9	capreomycin
rrl	1473417	n.-241C>T	upstream_gene_variant	0.9	linezolid
rrl	1473419	n.-239T>C	upstream_gene_variant	0.9	capreomycin
rrl	1473419	n.-239T>C	upstream_gene_variant	0.9	linezolid
rrl	1473420	n.-238A>G	upstream_gene_variant	0.9	capreomycin
rrl	1473420	n.-238A>G	upstream_gene_variant	0.9	linezolid
rrl	1473421	n.-237G>A	upstream_gene_variant	0.9	capreomycin
rrl	1473421	n.-237G>A	upstream_gene_variant	0.9	linezolid
rrl	1473756	n.99G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473756	n.99G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473758	n.101G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473806	n.149C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473877	n.220G>A	non_coding_transcript_exon_variant	0.95	capreomycin
rrl	1473877	n.220G>A	non_coding_transcript_exon_variant	0.95	linezolid
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	0.94	capreomycin	Uncertain significance
rrl	1473898	n.241C>T	non_coding_transcript_exon_variant	0.94	linezolid	Uncertain significance
rrl	1473899	n.242A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1473899	n.242A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1473995	n.338G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1473995	n.338G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474001	n.344C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Not assoc w R
rrl	1474001	n.344C>T	non_coding_transcript_exon_variant	1.0	linezolid	Not assoc w R
rrl	1474009	n.352A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474009	n.352A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474012	n.355C>T	non_coding_transcript_exon_variant	0.94	capreomycin
rrl	1474012	n.355C>T	non_coding_transcript_exon_variant	0.94	linezolid
rrl	1474093	n.436G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474093	n.436G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474099	n.442G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474099	n.442G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474103	n.446A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474140	n.483C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474151	n.494C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474181	n.524C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474249	n.592G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474291	n.635_649delTTCCTCTCCGGAGGA	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474291	n.635_649delTTCCTCTCCGGAGGA	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474308	n.651G>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474308	n.651G>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474310	n.653T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474356	n.699T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474356	n.699T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474362	n.705A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474376	n.719T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474376	n.719T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474639	n.982G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474639	n.982G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474794	n.1137C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474812	n.1155G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1474823	n.1166C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474823	n.1166C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474831	n.1174A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1474831	n.1174A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474904	n.1247G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474904	n.1247G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474956	n.1299C>T	non_coding_transcript_exon_variant	0.87	capreomycin
rrl	1474956	n.1299C>T	non_coding_transcript_exon_variant	0.87	linezolid
rrl	1474961	n.1304T>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474961	n.1304T>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474963	n.1306G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474963	n.1306G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474964	n.1307T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1474964	n.1307T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1474970	n.1313G>A	non_coding_transcript_exon_variant	0.93	capreomycin
rrl	1474970	n.1313G>A	non_coding_transcript_exon_variant	0.93	linezolid
rrl	1475006	n.1349A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475006	n.1349A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475013	n.1356G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475013	n.1356G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475088	n.1431A>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475088	n.1431A>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475199	n.1542G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475206	n.1549C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475209	n.1552G>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475209	n.1552G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475213	n.1556C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475213	n.1556C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475249	n.1592T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475249	n.1592T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475252	n.1595C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475252	n.1595C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475266	n.1609T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475266	n.1609T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475275	n.1618C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475275	n.1618C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475276	n.1619T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475276	n.1619T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475291	n.1634A>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475291	n.1634A>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475313	n.1656G>A	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475313	n.1656G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475315	n.1658A>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475355	n.1698C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475369	n.1712G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475369	n.1712G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475402	n.1745C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475402	n.1745C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475419	n.1762C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475483	n.1826C>T	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475505	n.1848G>A	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475526	n.1869C>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475599	n.1942A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475599	n.1942A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1475608	n.1951T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475638	n.1981C>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475638	n.1981C>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475642	n.1985T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475642	n.1985T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475657	n.2000A>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475657	n.2000A>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475659	n.2002G>T	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475659	n.2002G>T	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475761	n.2104_2106delCGCinsGT	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475761	n.2104_2106delCGCinsGT	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475765	n.2111delG	non_coding_transcript_exon_variant	0.96	capreomycin
rrl	1475765	n.2111delG	non_coding_transcript_exon_variant	0.96	linezolid
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1475881	n.2224T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.9	capreomycin	Not assoc w R
rrl	1475988	n.2331A>G	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1476031	n.2374C>T	non_coding_transcript_exon_variant	0.9	capreomycin
rrl	1476031	n.2374C>T	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.9	capreomycin
rrl	1476032	n.2375C>A	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476033	n.2376T>C	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476033	n.2376T>C	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476034	n.2377C>A	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476034	n.2377C>A	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476045	n.2388G>T	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476045	n.2388G>T	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.9	capreomycin
rrl	1476047	n.2390G>T	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476048	n.2391G>A	non_coding_transcript_exon_variant	0.9	capreomycin
rrl	1476048	n.2391G>A	non_coding_transcript_exon_variant	0.9	linezolid
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	0.9	capreomycin	Uncertain significance
rrl	1476049	n.2392C>T	non_coding_transcript_exon_variant	0.9	linezolid	Uncertain significance
rrl	1476086	n.2429G>A	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476086	n.2429G>A	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476089	n.2432T>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476089	n.2432T>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476095	n.2438C>G	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476095	n.2438C>G	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476105	n.2448_2449delGAinsT	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476105	n.2448_2449delGAinsT	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476115	n.2458T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476117	n.2460G>C	non_coding_transcript_exon_variant	1.0	capreomycin
rrl	1476117	n.2460G>C	non_coding_transcript_exon_variant	1.0	linezolid
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476224	n.2567A>G	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	1.0	capreomycin	Uncertain significance
rrl	1476281	n.2624T>C	non_coding_transcript_exon_variant	1.0	linezolid	Uncertain significance
rpsA	1833838	c.297G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833841	c.300C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833847	c.306C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833856	c.315A>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833874	c.333T>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833886	c.345C>G	synonymous_variant	1.0	pyrazinamide
rpsA	1833928	c.387G>C	synonymous_variant	1.0	pyrazinamide
rpsA	1833940	c.399C>G	synonymous_variant	1.0	pyrazinamide

Drug	Resistance	Supporting mutations	WHO confidence	Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin	rrs	n.462C>T	Uncertain significance	Mutation from literature
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid

TB-Profiler result