TB-Profiler result

Run: ERR4815909
Summary

Run ID: ERR4815909

Sample name:

Date: 01-04-2023 14:08:08

Number of reads: 2786542

Percentage reads mapped: 86.37

Strain: lineage4.8

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
gyrA 7572 p.Ser91Ala missense_variant 0.15 ofloxacin, moxifloxacin, levofloxacin, fluoroquinolones, ciprofloxacin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.21 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6170 p.His311Thr missense_variant 0.14
gyrB 6175 c.936G>A synonymous_variant 0.18
gyrB 6183 p.Thr315Met missense_variant 0.18
gyrB 6190 c.951A>G synonymous_variant 0.2
gyrB 6204 p.Ser322Thr missense_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7547 c.246C>T synonymous_variant 0.14
gyrA 7559 c.258G>C synonymous_variant 0.14
gyrA 7571 c.270G>C synonymous_variant 0.14
gyrA 7584 p.Ser95Ala missense_variant 0.2
gyrA 7589 c.288G>C synonymous_variant 0.23
gyrA 7591 p.Val97Ala missense_variant 0.23
gyrA 7596 p.Met99Leu missense_variant 0.23
gyrA 7600 p.Ala100Val missense_variant 0.18
gyrA 7625 c.324G>C synonymous_variant 0.13
gyrA 8752 p.Ala484Val missense_variant 0.13
gyrA 8933 c.1632G>A synonymous_variant 1.0
gyrA 9152 p.Tyr617* stop_gained 0.14
gyrA 9806 c.2505G>A synonymous_variant 0.12
rpoB 760010 c.204C>T synonymous_variant 0.12
rpoB 760208 p.Ile134Met missense_variant 0.13
rpoB 760746 p.Leu314Phe missense_variant 0.15
rpoB 762024 p.Val740Ile missense_variant 0.23
rpoB 762029 c.2223C>G synonymous_variant 0.13
rpoB 762050 c.2244G>A synonymous_variant 0.17
rpoB 762051 p.His749Tyr missense_variant 0.31
rpoB 762057 p.Ile751Val missense_variant 0.33
rpoB 762062 c.2256T>C synonymous_variant 0.33
rpoB 762065 c.2259T>C synonymous_variant 0.33
rpoB 762071 p.Asp755Glu missense_variant 0.29
rpoB 762080 c.2274G>C synonymous_variant 0.23
rpoB 762085 p.Ala760Glu missense_variant 0.2
rpoB 762089 c.2283G>A synonymous_variant 0.2
rpoB 762092 c.2286G>A synonymous_variant 0.19
rpoB 762185 c.2379G>C synonymous_variant 0.15
rpoB 762194 c.2388G>C synonymous_variant 0.21
rpoB 762200 c.2394C>T synonymous_variant 0.15
rpoB 762218 c.2412T>C synonymous_variant 0.14
rpoB 762233 c.2427G>C synonymous_variant 0.21
rpoB 762234 p.Pro810Ser missense_variant 0.2
rpoB 762245 c.2439G>C synonymous_variant 0.19
rpoB 762247 p.Leu814Pro missense_variant 0.12
rpoB 762254 c.2448T>C synonymous_variant 0.18
rpoB 762642 p.Val946Ile missense_variant 0.14
rpoB 762879 p.Met1025Leu missense_variant 0.21
rpoC 762887 c.-483G>C upstream_gene_variant 0.13
rpoC 762896 c.-474G>C upstream_gene_variant 0.12
rpoC 762899 c.-471G>C upstream_gene_variant 0.11
rpoC 762929 c.-441G>T upstream_gene_variant 0.35
rpoC 762938 c.-432G>C upstream_gene_variant 0.22
rpoC 762956 c.-414G>C upstream_gene_variant 0.15
rpoC 762980 c.-390T>C upstream_gene_variant 0.14
rpoC 762983 c.-387C>G upstream_gene_variant 0.15
rpoC 762989 c.-381G>C upstream_gene_variant 0.18
rpoC 762995 c.-375G>C upstream_gene_variant 0.17
rpoB 763005 p.Cys1067Gly missense_variant 0.15
rpoC 763031 c.-339T>C upstream_gene_variant 0.2
rpoB 763038 p.Thr1078Ala missense_variant 0.33
rpoC 763043 c.-327G>C upstream_gene_variant 0.41
rpoC 763053 c.-317T>C upstream_gene_variant 0.43
rpoC 763070 c.-300T>C upstream_gene_variant 0.53
rpoB 763077 p.Val1091Thr missense_variant 0.5
rpoC 763103 c.-267G>C upstream_gene_variant 0.47
rpoC 763115 c.-255T>C upstream_gene_variant 0.29
rpoB 763119 p.Asn1105Asp missense_variant 0.29
rpoC 763127 c.-243G>C upstream_gene_variant 0.2
rpoC 763133 c.-237G>C upstream_gene_variant 0.2
rpoC 763642 c.273G>C synonymous_variant 0.14
rpoC 763648 c.279C>T synonymous_variant 0.14
rpoC 763657 p.Glu96Asp missense_variant 0.14
rpoC 763660 c.291T>G synonymous_variant 0.15
rpoC 763663 c.294C>T synonymous_variant 0.14
rpoC 763666 c.297G>C synonymous_variant 0.21
rpoC 763675 c.306C>G synonymous_variant 0.24
rpoC 763699 c.330G>T synonymous_variant 0.41
rpoC 763708 c.339G>C synonymous_variant 0.33
rpoC 763714 c.345G>C synonymous_variant 0.31
rpoC 763717 c.348T>C synonymous_variant 0.28
rpoC 763718 p.Leu117Val missense_variant 0.29
rpoC 763723 c.354G>C synonymous_variant 0.28
rpoC 763724 p.Asp119Asn missense_variant 0.28
rpoC 763729 c.360G>C synonymous_variant 0.3
rpoC 763732 c.363C>G synonymous_variant 0.33
rpoC 763735 c.366G>C synonymous_variant 0.35
rpoC 763744 c.375G>C synonymous_variant 0.37
rpoC 763751 p.Ile128Val missense_variant 0.37
rpoC 763772 p.Val135Met missense_variant 0.17
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.15
rpoC 764410 c.1041G>C synonymous_variant 0.12
rpoC 764424 p.Asn352Thr missense_variant 0.14
rpoC 764428 c.1059G>A synonymous_variant 0.14
rpoC 764431 c.1062G>C synonymous_variant 0.14
rpoC 764434 c.1065A>G synonymous_variant 0.14
rpoC 764435 c.1066_1068delAGGinsCGC synonymous_variant 0.14
rpoC 764441 p.Ile358Leu missense_variant 0.17
rpoC 764446 p.Asp359Glu missense_variant 0.17
rpoC 764455 c.1086G>C synonymous_variant 0.19
rpoC 764458 c.1089G>C synonymous_variant 0.19
rpoC 764461 c.1092A>G synonymous_variant 0.21
rpoC 764485 c.1116G>C synonymous_variant 0.23
rpoC 764491 c.1122G>T synonymous_variant 0.17
rpoC 764497 c.1128A>G synonymous_variant 0.1
rpoC 764503 c.1134G>T synonymous_variant 0.19
rpoC 764509 c.1140G>C synonymous_variant 0.24
rpoC 764512 c.1143G>C synonymous_variant 0.19
rpoC 764530 c.1161C>T synonymous_variant 0.12
rpoC 764536 c.1167G>C synonymous_variant 0.19
rpoC 764543 p.Thr392Ala missense_variant 0.17
rpoC 764548 c.1179G>C synonymous_variant 0.2
rpoC 764551 c.1182G>C synonymous_variant 0.18
rpoC 764573 p.Leu402Ile missense_variant 0.17
rpoC 764578 c.1209C>G synonymous_variant 0.17
rpoC 764581 c.1212T>C synonymous_variant 0.17
rpoC 764582 p.Leu405Met missense_variant 0.17
rpoC 764602 c.1233C>T synonymous_variant 0.23
rpoC 764605 c.1236G>T synonymous_variant 0.22
rpoC 764611 c.1242G>T synonymous_variant 0.25
rpoC 764632 c.1263T>A synonymous_variant 0.21
rpoC 764647 c.1278C>T synonymous_variant 0.3
rpoC 764650 c.1281G>T synonymous_variant 0.22
rpoC 764653 c.1284G>C synonymous_variant 0.2
rpoC 764656 c.1287C>G synonymous_variant 0.13
rpoC 764662 c.1293G>C synonymous_variant 0.2
rpoC 764677 c.1308C>G synonymous_variant 0.17
rpoC 764678 p.Lys437Gln missense_variant 0.2
rpoC 764706 p.Leu446Gln missense_variant 0.12
rpoC 764713 c.1344G>C synonymous_variant 0.12
rpoC 766033 c.2664G>A synonymous_variant 0.14
rpoC 766135 c.2766G>T synonymous_variant 0.17
rpoC 766530 p.Arg1054Gln missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781751 c.192G>C synonymous_variant 0.15
rpsL 781760 c.201T>C synonymous_variant 0.14
rpsL 781766 c.207C>T synonymous_variant 0.22
rpsL 781796 p.Met79Ile missense_variant 0.21
rpsL 781802 c.243G>C synonymous_variant 0.21
rpsL 781811 c.252C>T synonymous_variant 0.18
rpsL 781814 c.255C>T synonymous_variant 0.18
rpsL 781817 c.258G>T synonymous_variant 0.18
rpsL 781832 c.273T>C synonymous_variant 0.18
rplC 800669 c.-140G>A upstream_gene_variant 0.13
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1304852 p.Gly641Ala missense_variant 0.13
fbiC 1305001 p.Ile691Val missense_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471839 n.-7G>A upstream_gene_variant 0.33
rrs 1471853 n.8T>C non_coding_transcript_exon_variant 0.22
rrs 1471917 n.72G>C non_coding_transcript_exon_variant 0.14
rrs 1472068 n.223T>G non_coding_transcript_exon_variant 0.5
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.67
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.75
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 1.0
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.23
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.89
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.89
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.89
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.81
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.81
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.24
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.78
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 1.0
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 1.0
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.52
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.76
rrs 1472279 n.434T>G non_coding_transcript_exon_variant 0.3
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 0.4
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 1.0
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.67
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.67
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.9
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.91
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.95
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.95
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.96
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.95
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.8
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.94
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.19
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 1.0
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.76
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.76
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.76
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 1.0
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 1.0
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.67
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.89
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.18
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.21
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.23
rrs 1472779 n.934G>A non_coding_transcript_exon_variant 0.12
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.21
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.66
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.32
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.41
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 1.0
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.5
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.23
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 1.0
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.95
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.94
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 1.0
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.99
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.71
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.97
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.86
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.83
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 1.0
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.99
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 1.0
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 1.0
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.63
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.8
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 1.0
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 1.0
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.96
rrs 1473101 n.1256C>T non_coding_transcript_exon_variant 0.48
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.48
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.92
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.92
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.12
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.74
rrs 1473122 n.1281delA non_coding_transcript_exon_variant 0.62
rrs 1473122 n.1278A>T non_coding_transcript_exon_variant 0.84
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.73
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.95
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.93
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.91
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.94
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.98
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.98
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.97
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 1.0
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.94
rrs 1473293 n.1449delA non_coding_transcript_exon_variant 0.8
rrs 1473293 n.1449A>G non_coding_transcript_exon_variant 0.88
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.85
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.93
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.91
rrl 1473384 n.-274A>G upstream_gene_variant 0.33
rrl 1473580 n.-78G>T upstream_gene_variant 0.14
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 1.0
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 1.0
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 1.0
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 1.0
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 1.0
rrl 1474200 n.545delT non_coding_transcript_exon_variant 1.0
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.15
rrl 1474275 n.618T>C non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.5
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.5
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.5
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.23
rrl 1474628 n.971C>T non_coding_transcript_exon_variant 0.31
rrl 1474634 n.977T>C non_coding_transcript_exon_variant 0.5
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 1.0
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.67
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 0.5
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 1.0
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 0.4
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.57
rrl 1474774 n.1117A>G non_coding_transcript_exon_variant 0.5
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.75
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.67
rrl 1474802 n.1145T>C non_coding_transcript_exon_variant 0.67
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 1.0
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.4
rrl 1474904 n.1247G>T non_coding_transcript_exon_variant 0.5
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.5
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.5
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 1.0
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 1.0
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 1.0
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 1.0
rrl 1475172 n.1515A>G non_coding_transcript_exon_variant 1.0
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 0.5
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.67
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.38
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.11
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.76
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.71
rrl 1475892 n.2235A>G non_coding_transcript_exon_variant 0.18
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.36
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.67
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.67
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.29
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.5
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.67
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.5
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.67
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.67
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 1.0
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.5
rrl 1476229 n.2572C>G non_coding_transcript_exon_variant 1.0
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 1.0
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.71
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 1.0
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.67
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 1.0
rrl 1476336 n.2679C>T non_coding_transcript_exon_variant 0.19
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.89
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.87
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.9
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.89
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.89
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.87
rrl 1476501 n.2844C>T non_coding_transcript_exon_variant 0.17
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.7
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.8
rpsA 1834234 c.693G>C synonymous_variant 0.22
rpsA 1834240 c.699T>C synonymous_variant 0.2
rpsA 1834246 c.705G>T synonymous_variant 0.3
rpsA 1834249 c.708T>C synonymous_variant 0.34
rpsA 1834261 c.720A>G synonymous_variant 0.36
rpsA 1834264 c.723G>C synonymous_variant 0.37
rpsA 1834294 c.753G>C synonymous_variant 0.41
rpsA 1834298 p.Gln253Glu missense_variant 0.37
rpsA 1834306 c.765T>C synonymous_variant 0.29
rpsA 1834307 p.Asp256Gln missense_variant 0.29
rpsA 1834312 c.771G>A synonymous_variant 0.11
rpsA 1834327 c.786G>T synonymous_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 0.99
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
clpC1 4038160 c.2545T>C stop_lost&splice_region_variant 0.11
clpC1 4038177 p.Pro843Gln missense_variant 0.13
clpC1 4039691 c.1014G>C synonymous_variant 0.14
clpC1 4039880 p.Glu275Asp missense_variant 0.11
clpC1 4040057 c.648C>T synonymous_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0