TB-Profiler result

Run: ERR4819017
Summary

Run ID: ERR4819017

Sample name:

Date: 01-04-2023 15:52:45

Number of reads: 733198

Percentage reads mapped: 41.99

Strain: lineage3

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.15 rifampicin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.13 streptomycin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.74 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.3 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.19 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 7024 c.1787delA frameshift_variant 0.18
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8392 p.Tyr364Cys missense_variant 0.14
gyrA 8405 p.His368Gln missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 761084 c.1278C>A synonymous_variant 0.17
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.15
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.14
rpoB 761102 c.1296A>G synonymous_variant 0.18
rpoB 761557 p.Ala584Gly missense_variant 0.11
rpoB 761567 p.Met587Ile missense_variant 0.11
rpoB 761570 c.1764T>C synonymous_variant 0.11
rpoB 762143 c.2337T>C synonymous_variant 0.12
rpoB 762149 c.2343G>C synonymous_variant 0.13
rpoB 762156 p.Val784Ile missense_variant 0.14
rpoB 762167 c.2361T>C synonymous_variant 0.12
rpoB 762176 c.2370T>C synonymous_variant 0.13
rpoB 762177 p.Arg791Thr missense_variant 0.13
rpoB 762181 p.Asp792Ala missense_variant 0.13
rpoB 762185 c.2379G>C synonymous_variant 0.19
rpoB 762194 c.2388G>C synonymous_variant 0.17
rpoB 762200 c.2394C>T synonymous_variant 0.2
rpoB 762218 c.2412T>C synonymous_variant 0.12
rpoC 762434 c.-936T>G upstream_gene_variant 0.95
rpoB 762879 p.Met1025Leu missense_variant 0.2
rpoC 762902 c.-468C>T upstream_gene_variant 0.36
rpoC 762911 c.-459C>T upstream_gene_variant 0.41
rpoC 762917 c.-453C>T upstream_gene_variant 0.38
rpoC 762920 c.-450C>T upstream_gene_variant 0.36
rpoC 762929 c.-441G>T upstream_gene_variant 0.38
rpoC 762944 c.-426C>T upstream_gene_variant 0.32
rpoC 762956 c.-414G>C upstream_gene_variant 0.18
rpoC 762962 c.-408C>T upstream_gene_variant 0.24
rpoC 762983 c.-387C>T upstream_gene_variant 0.17
rpoC 762989 c.-381G>C upstream_gene_variant 0.16
rpoC 762995 c.-375G>T upstream_gene_variant 0.13
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763053 c.-317T>C upstream_gene_variant 0.12
rpoC 763070 c.-300T>C upstream_gene_variant 0.14
rpoB 763077 p.Val1091Thr missense_variant 0.18
rpoC 763103 c.-267G>C upstream_gene_variant 0.18
rpoC 763115 c.-255T>C upstream_gene_variant 0.18
rpoB 763119 p.Asn1105Asp missense_variant 0.18
rpoC 763370 p.Val1Met missense_variant 0.13
rpoC 763528 c.159G>A synonymous_variant 0.12
rpoC 763531 c.162G>C synonymous_variant 0.12
rpoC 763534 c.165T>C synonymous_variant 0.13
rpoC 763546 c.177A>G synonymous_variant 0.15
rpoC 763550 p.Tyr61Ala missense_variant 0.13
rpoC 763570 c.201G>C synonymous_variant 0.15
rpoC 763578 p.Phe70Tyr missense_variant 0.17
rpoC 763647 p.Gly93Ala missense_variant 0.14
rpoC 763655 p.Glu96Lys missense_variant 0.2
rpoC 763660 c.291T>C synonymous_variant 0.13
rpoC 763666 c.297G>T synonymous_variant 0.13
rpoC 763669 c.300C>G synonymous_variant 0.12
rpoC 763696 c.327T>C synonymous_variant 0.14
rpoC 763699 c.330G>T synonymous_variant 0.27
rpoC 763708 c.339G>C synonymous_variant 0.29
rpoC 763714 c.345G>C synonymous_variant 0.29
rpoC 763717 c.348T>C synonymous_variant 0.28
rpoC 763718 p.Leu117Val missense_variant 0.16
rpoC 763723 c.354G>C synonymous_variant 0.24
rpoC 763724 p.Asp119Asn missense_variant 0.24
rpoC 763729 c.360G>C synonymous_variant 0.24
rpoC 763732 c.363C>G synonymous_variant 0.18
rpoC 763735 c.366G>C synonymous_variant 0.17
rpoC 763751 p.Ile128Val missense_variant 0.2
rpoC 763772 p.Val135Met missense_variant 0.17
rpoC 764321 p.Pro318Thr missense_variant 0.17
rpoC 764485 c.1116G>C synonymous_variant 0.22
rpoC 764491 c.1122G>T synonymous_variant 0.17
rpoC 764503 c.1134G>T synonymous_variant 0.18
rpoC 764509 c.1140G>C synonymous_variant 0.29
rpoC 764512 c.1143G>C synonymous_variant 0.19
rpoC 764521 c.1152T>C synonymous_variant 0.25
rpoC 764536 c.1167G>C synonymous_variant 0.25
rpoC 764543 p.Thr392Ala missense_variant 0.18
rpoC 764566 c.1197C>G synonymous_variant 0.17
rpoC 764581 c.1212T>C synonymous_variant 0.12
rpoC 764582 p.Leu405Met missense_variant 0.12
rpoC 764602 c.1233C>T synonymous_variant 0.17
rpoC 764605 c.1236G>T synonymous_variant 0.21
rpoC 764611 c.1242G>C synonymous_variant 0.17
rpoC 764623 c.1254C>G synonymous_variant 0.12
rpoC 764632 c.1263T>C synonymous_variant 0.24
rpoC 764635 c.1266C>G synonymous_variant 0.12
rpoC 764647 c.1278C>T synonymous_variant 0.11
rpoC 764650 c.1281G>T synonymous_variant 0.14
rpoC 764653 c.1284G>C synonymous_variant 0.2
rpoC 764656 c.1287C>T synonymous_variant 0.12
rpoC 764692 c.1323C>T synonymous_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 775675 p.Trp936Arg missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpR5 779342 p.Ala118Val missense_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781706 c.147T>G synonymous_variant 0.14
rpsL 781751 c.192G>C synonymous_variant 0.18
rpsL 781754 c.195G>A synonymous_variant 0.15
rpsL 781760 c.201T>C synonymous_variant 0.27
rpsL 781766 c.207C>T synonymous_variant 0.3
rpsL 781772 c.213C>T synonymous_variant 0.22
rpsL 781796 p.Met79Ile missense_variant 0.4
rpsL 781802 c.243G>C synonymous_variant 0.42
rpsL 781805 c.246G>T synonymous_variant 0.32
rpsL 781811 c.252C>T synonymous_variant 0.44
rpsL 781814 c.255C>T synonymous_variant 0.42
rpsL 781817 c.258G>T synonymous_variant 0.42
rpsL 781829 c.270G>C synonymous_variant 0.29
rpsL 781832 c.273T>C synonymous_variant 0.44
rpsL 781835 c.276T>C synonymous_variant 0.17
rpsL 781838 c.279G>T synonymous_variant 0.25
rpsL 781841 c.282C>T synonymous_variant 0.19
rpsL 781851 p.Ile98Val missense_variant 0.18
fbiC 1305215 p.Ser762Asn missense_variant 1.0
embR 1416934 c.414G>A synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.29
rrs 1472078 n.233C>T non_coding_transcript_exon_variant 0.29
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.33
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.42
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.61
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.26
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.28
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.33
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.36
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.38
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.99
rrs 1472155 n.310C>T non_coding_transcript_exon_variant 0.35
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.32
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.67
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.3
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.96
rrs 1472258 n.413A>G non_coding_transcript_exon_variant 0.14
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.15
rrs 1472285 n.440A>G non_coding_transcript_exon_variant 1.0
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 1.0
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.57
rrs 1472496 n.651T>A non_coding_transcript_exon_variant 0.6
rrs 1472498 n.653C>A non_coding_transcript_exon_variant 0.71
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.71
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.77
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.74
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.73
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.83
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.84
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.85
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.85
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.85
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.87
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.6
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.79
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.24
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.98
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.85
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.85
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.32
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.88
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.85
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.47
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.39
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.48
rrs 1472670 n.825G>T non_coding_transcript_exon_variant 0.48
rrs 1472673 n.828T>A non_coding_transcript_exon_variant 0.75
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.8
rrs 1472674 n.829T>G non_coding_transcript_exon_variant 0.19
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.85
rrs 1472677 n.832C>T non_coding_transcript_exon_variant 0.85
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.72
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.54
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.67
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.29
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.67
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.72
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.72
rrs 1472755 n.910G>A non_coding_transcript_exon_variant 0.18
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.71
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.3
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.67
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.68
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.91
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.17
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.52
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.86
rrs 1472840 n.995A>G non_coding_transcript_exon_variant 0.33
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.4
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.87
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.59
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.24
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.59
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.89
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.92
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.88
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.97
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.63
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.6
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.97
rrs 1472992 n.1147A>G non_coding_transcript_exon_variant 0.21
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.25
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.96
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.94
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.94
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.95
rrs 1473080 n.1235C>T non_coding_transcript_exon_variant 0.12
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.95
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.87
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.48
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.75
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.92
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.93
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.92
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.71
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.85
rrs 1473122 n.1278A>T non_coding_transcript_exon_variant 0.18
rrs 1473130 n.1285G>A non_coding_transcript_exon_variant 0.22
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.85
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.13
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.82
rrs 1473172 n.1327T>G non_coding_transcript_exon_variant 0.33
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.42
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.45
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.9
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.93
rrs 1473270 n.1425G>A non_coding_transcript_exon_variant 0.27
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.91
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.88
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.53
rrs 1473293 n.1449delA non_coding_transcript_exon_variant 0.52
rrs 1473300 n.1455C>T non_coding_transcript_exon_variant 0.54
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.91
rrs 1473301 n.1456T>G non_coding_transcript_exon_variant 0.94
rrs 1473305 n.1460G>T non_coding_transcript_exon_variant 0.22
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.85
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.14
rrl 1473384 n.-274A>G upstream_gene_variant 0.43
rrl 1474130 n.473C>T non_coding_transcript_exon_variant 0.5
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.5
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.6
rrl 1474164 n.507C>T non_coding_transcript_exon_variant 0.5
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.18
rrl 1474181 n.524C>A non_coding_transcript_exon_variant 0.79
rrl 1474182 n.525C>G non_coding_transcript_exon_variant 0.12
rrl 1474183 n.526T>G non_coding_transcript_exon_variant 0.12
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.75
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.12
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.89
rrl 1474199 n.542G>C non_coding_transcript_exon_variant 0.82
rrl 1474200 n.545delT non_coding_transcript_exon_variant 0.94
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 1.0
rrl 1474269 n.612C>T non_coding_transcript_exon_variant 0.67
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.67
rrl 1474272 n.615C>T non_coding_transcript_exon_variant 0.67
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.67
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 0.75
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.91
rrl 1474492 n.835A>G non_coding_transcript_exon_variant 0.27
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.64
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.91
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.91
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.73
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.92
rrl 1474520 n.863A>T non_coding_transcript_exon_variant 0.25
rrl 1474525 n.868A>G non_coding_transcript_exon_variant 0.2
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.87
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.2
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 1.0
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.25
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.92
rrl 1474615 n.958A>T non_coding_transcript_exon_variant 0.18
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.62
rrl 1474636 n.979A>C non_coding_transcript_exon_variant 0.75
rrl 1474636 n.979A>G non_coding_transcript_exon_variant 0.67
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.38
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.67
rrl 1474638 n.981C>T non_coding_transcript_exon_variant 0.67
rrl 1474652 n.995T>G non_coding_transcript_exon_variant 0.22
rrl 1474658 n.1001A>G non_coding_transcript_exon_variant 0.57
rrl 1474663 n.1006C>T non_coding_transcript_exon_variant 0.67
rrl 1474666 n.1009T>G non_coding_transcript_exon_variant 0.33
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.5
rrl 1474677 n.1020A>G non_coding_transcript_exon_variant 0.5
rrl 1474687 n.1030C>G non_coding_transcript_exon_variant 0.33
rrl 1474692 n.1035G>A non_coding_transcript_exon_variant 0.33
rrl 1474734 n.1077G>C non_coding_transcript_exon_variant 0.8
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.91
rrl 1474774 n.1117A>G non_coding_transcript_exon_variant 0.17
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.11
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474798 n.1141C>G non_coding_transcript_exon_variant 0.11
rrl 1474800 n.1143T>C non_coding_transcript_exon_variant 0.11
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.3
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 0.75
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.14
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.89
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.86
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.78
rrl 1474832 n.1175A>G non_coding_transcript_exon_variant 0.17
rrl 1474837 n.1180A>G non_coding_transcript_exon_variant 0.18
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 1.0
rrl 1474883 n.1226T>C non_coding_transcript_exon_variant 0.33
rrl 1474901 n.1244A>G non_coding_transcript_exon_variant 0.25
rrl 1474903 n.1246T>C non_coding_transcript_exon_variant 0.6
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.4
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.4
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 1.0
rrl 1475769 n.2112T>C non_coding_transcript_exon_variant 1.0
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.67
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 0.44
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.62
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.92
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.8
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.64
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.82
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.82
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.55
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.67
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.4
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.6
rrl 1475945 n.2288C>A non_coding_transcript_exon_variant 0.29
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.33
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.5
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.4
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.5
rrl 1475997 n.2340A>T non_coding_transcript_exon_variant 0.4
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 0.4
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.4
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.62
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.22
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.7
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.7
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.5
rrl 1476207 n.2550T>C non_coding_transcript_exon_variant 0.22
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.67
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.62
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.38
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.5
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.53
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.53
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.12
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.81
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.81
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.12
rrl 1476253 n.2596A>G non_coding_transcript_exon_variant 0.12
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.12
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.81
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.94
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.69
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.33
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.57
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.92
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.92
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.91
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.86
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.72
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.75
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.75
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.73
rrl 1476513 n.2856G>T non_coding_transcript_exon_variant 0.59
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.62
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.17
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.27
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.5
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.67
rrl 1476528 n.2871A>G non_coding_transcript_exon_variant 0.15
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.55
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.38
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.42
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.31
rrl 1476548 n.2891T>C non_coding_transcript_exon_variant 0.15
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.33
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.17
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.75
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.75
rrl 1476594 n.2937C>A non_coding_transcript_exon_variant 0.33
rrl 1476600 n.2943A>C non_coding_transcript_exon_variant 0.5
rrl 1476603 n.2946G>T non_coding_transcript_exon_variant 0.33
rrl 1476607 n.2950C>T non_coding_transcript_exon_variant 0.27
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.82
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.82
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.58
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.75
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.62
rrl 1476628 n.2971T>G non_coding_transcript_exon_variant 0.57
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.55
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.3
rrl 1476633 n.2976A>G non_coding_transcript_exon_variant 0.4
rrl 1476664 n.3007T>A non_coding_transcript_exon_variant 0.43
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.57
inhA 1673568 c.-634C>A upstream_gene_variant 0.2
rpsA 1833679 c.138G>C synonymous_variant 0.1
rpsA 1833694 c.153G>C synonymous_variant 0.11
rpsA 1833721 c.180A>G synonymous_variant 0.2
rpsA 1833727 c.186G>C synonymous_variant 0.14
rpsA 1833732 p.Pro64Leu missense_variant 0.18
rpsA 1833736 c.195C>T synonymous_variant 0.18
rpsA 1833742 c.201A>G synonymous_variant 0.17
rpsA 1833949 c.408T>C synonymous_variant 0.12
rpsA 1833952 c.411C>T synonymous_variant 0.12
rpsA 1833955 c.414G>C synonymous_variant 0.12
rpsA 1833961 c.420C>G synonymous_variant 0.12
rpsA 1833970 c.429G>C synonymous_variant 0.17
rpsA 1833979 c.438T>C synonymous_variant 0.18
rpsA 1833991 c.450C>A synonymous_variant 0.11
rpsA 1833994 c.453G>C synonymous_variant 0.19
rpsA 1834015 c.474G>C synonymous_variant 0.12
rpsA 1834195 c.654G>C synonymous_variant 0.2
rpsA 1834219 c.678C>G synonymous_variant 0.14
rpsA 1834222 c.681T>C synonymous_variant 0.14
rpsA 1834225 c.684C>G synonymous_variant 0.13
rpsA 1834228 c.687C>T synonymous_variant 0.26
rpsA 1834231 c.690T>C synonymous_variant 0.13
rpsA 1834234 c.693G>C synonymous_variant 0.17
rpsA 1834240 c.699T>C synonymous_variant 0.17
rpsA 1834246 c.705G>T synonymous_variant 0.27
rpsA 1834249 c.708T>C synonymous_variant 0.33
rpsA 1834261 c.720A>G synonymous_variant 0.41
rpsA 1834264 c.723G>C synonymous_variant 0.41
rpsA 1834285 c.744G>C synonymous_variant 0.11
rpsA 1834294 c.753G>C synonymous_variant 0.29
rpsA 1834298 p.Gln253Glu missense_variant 0.31
rpsA 1834306 c.765T>C synonymous_variant 0.31
rpsA 1834307 p.Asp256Gln missense_variant 0.25
rpsA 1834312 c.771G>A synonymous_variant 0.25
rpsA 1834327 c.786G>T synonymous_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154206 p.Ala636Thr missense_variant 0.12
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
kasA 2519057 p.Thr315Ser missense_variant 0.18
kasA 2519062 c.948T>G synonymous_variant 0.22
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
folC 2746268 p.Thr444Ile missense_variant 1.0
pepQ 2859624 c.795G>A synonymous_variant 0.92
pepQ 2860207 p.Leu71Arg missense_variant 0.12
Rv2752c 3065361 c.831C>A synonymous_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568847 c.-168G>T upstream_gene_variant 0.12
fbiB 3640671 c.-864T>C upstream_gene_variant 1.0
clpC1 4039638 p.Ile356Thr missense_variant 0.14
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246563 p.Leu17Trp missense_variant 0.1
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0