Run ID: SRR7070469
Sample name:
Date: 2024-05-20T09:29:35.333187
Number of reads: 1449955
Percentage reads mapped: 78.49
Median coverage: 44.5
Strain: lineage4.3.1.1
Spoligotype:
Drug-resistance: Other
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage4.3 | Euro-American (LAM) | None | 1.0 |
lineage4.3.1 | Euro-American (LAM) | None | 1.0 |
lineage4 | Euro-American | None | 1.0 |
lineage4.3.1.1 | Euro-American (LAM) | None | 1.0 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | rrs | n.888G>A | Uncertain significance | Mutation from literature |
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|---|---|---|---|---|---|---|
rrs | 1472733 | n.888G>A | non_coding_transcript_exon_variant | 0.56 | streptomycin | Uncertain significance | Mutation from literature |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
rpoC | 764995 | c.1626C>G | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1471660 | n.-186G>A | upstream_gene_variant | 1.0 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472108 | n.263C>T | non_coding_transcript_exon_variant | 0.38 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472122 | n.277G>T | non_coding_transcript_exon_variant | 0.4 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472123 | n.278A>T | non_coding_transcript_exon_variant | 0.4 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472124 | n.279C>T | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1472150 | n.305T>A | non_coding_transcript_exon_variant | 0.48 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
rrs | 1472155 | n.310C>T | non_coding_transcript_exon_variant | 0.38 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472160 | n.315C>T | non_coding_transcript_exon_variant | 0.54 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472225 | n.380C>A | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
rrs | 1472251 | n.406G>A | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
rrs | 1472530 | n.685G>A | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472537 | n.692C>T | non_coding_transcript_exon_variant | 0.65 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472544 | n.699C>A | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472545 | n.700A>T | non_coding_transcript_exon_variant | 0.71 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472549 | n.704G>A | non_coding_transcript_exon_variant | 0.28 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472566 | n.721G>A | non_coding_transcript_exon_variant | 0.68 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472571 | n.726G>C | non_coding_transcript_exon_variant | 0.68 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472579 | n.734G>T | non_coding_transcript_exon_variant | 0.69 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472581 | n.736A>T | non_coding_transcript_exon_variant | 0.89 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
rrs | 1472584 | n.739A>T | non_coding_transcript_exon_variant | 0.21 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472598 | n.753A>C | non_coding_transcript_exon_variant | 0.7 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472599 | n.754G>T | non_coding_transcript_exon_variant | 0.7 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472616 | n.771G>A | non_coding_transcript_exon_variant | 0.72 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472655 | n.810G>A | non_coding_transcript_exon_variant | 0.77 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472658 | n.813G>A | non_coding_transcript_exon_variant | 0.77 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472661 | n.816A>G | non_coding_transcript_exon_variant | 0.83 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472670 | n.825G>T | non_coding_transcript_exon_variant | 0.75 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472673 | n.828T>G | non_coding_transcript_exon_variant | 0.78 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472675 | n.830T>C | non_coding_transcript_exon_variant | 0.84 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | ||||||
capreomycin | Uncertain significance | |||||
rrs | 1472677 | n.832C>T | non_coding_transcript_exon_variant | 0.84 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472681 | n.837_838delTT | non_coding_transcript_exon_variant | 0.83 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472687 | n.842_843insC | non_coding_transcript_exon_variant | 0.83 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472690 | n.845C>A | non_coding_transcript_exon_variant | 0.83 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472697 | n.852T>A | non_coding_transcript_exon_variant | 0.83 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1472713 | n.868T>C | non_coding_transcript_exon_variant | 0.79 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472716 | n.871C>T | non_coding_transcript_exon_variant | 0.68 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472742 | n.897C>T | non_coding_transcript_exon_variant | 0.56 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472744 | n.899A>G | non_coding_transcript_exon_variant | 0.55 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472790 | n.945T>C | non_coding_transcript_exon_variant | 0.58 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472895 | n.1050C>T | non_coding_transcript_exon_variant | 0.47 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472954 | n.1109T>C | non_coding_transcript_exon_variant | 0.52 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472956 | n.1111T>C | non_coding_transcript_exon_variant | 0.52 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472957 | n.1112C>T | non_coding_transcript_exon_variant | 0.57 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472973 | n.1128A>G | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1472990 | n.1145A>G | non_coding_transcript_exon_variant | 0.42 | kanamycin | Not assoc w R |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Not assoc w R | |||||
rrs | 1472992 | n.1147A>G | non_coding_transcript_exon_variant | 0.42 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1473005 | n.1160C>T | non_coding_transcript_exon_variant | 0.61 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1473035 | n.1190G>A | non_coding_transcript_exon_variant | 0.62 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473055 | n.1210C>T | non_coding_transcript_exon_variant | 0.5 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473056 | n.1211A>T | non_coding_transcript_exon_variant | 0.67 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473066 | n.1221A>G | non_coding_transcript_exon_variant | 0.61 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473172 | n.1327T>G | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473173 | n.1328C>T | non_coding_transcript_exon_variant | 0.44 | kanamycin | Uncertain significance |
amikacin | Not assoc w R | |||||
streptomycin | Not assoc w R | |||||
capreomycin | Not assoc w R | |||||
rrs | 1473288 | n.1443C>G | non_coding_transcript_exon_variant | 0.25 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrs | 1473293 | n.1449delA | non_coding_transcript_exon_variant | 0.26 | kanamycin | |
amikacin | ||||||
streptomycin | ||||||
capreomycin | ||||||
rrs | 1473316 | n.1471C>T | non_coding_transcript_exon_variant | 0.3 | kanamycin | Uncertain significance |
amikacin | Uncertain significance | |||||
streptomycin | Uncertain significance | |||||
capreomycin | Uncertain significance | |||||
rrl | 1474722 | n.1065T>C | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1474734 | n.1077G>T | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474749 | n.1092C>T | non_coding_transcript_exon_variant | 0.85 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474753 | n.1097delC | non_coding_transcript_exon_variant | 0.82 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474760 | n.1103A>G | non_coding_transcript_exon_variant | 0.64 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474779 | n.1122G>A | non_coding_transcript_exon_variant | 0.65 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474780 | n.1123C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474782 | n.1125G>A | non_coding_transcript_exon_variant | 0.61 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1474790 | n.1133C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474794 | n.1137C>T | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474801 | n.1144G>A | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474802 | n.1145T>C | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474823 | n.1166C>G | non_coding_transcript_exon_variant | 1.0 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474831 | n.1174A>T | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474837 | n.1180A>G | non_coding_transcript_exon_variant | 0.53 | capreomycin | |
linezolid | ||||||
rrl | 1474864 | n.1207C>T | non_coding_transcript_exon_variant | 0.91 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1475754 | n.2097G>A | non_coding_transcript_exon_variant | 0.6 | capreomycin | |
linezolid | ||||||
rrl | 1475881 | n.2224T>C | non_coding_transcript_exon_variant | 0.44 | capreomycin | |
linezolid | ||||||
rrl | 1475883 | n.2226A>C | non_coding_transcript_exon_variant | 0.77 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475892 | n.2235A>G | non_coding_transcript_exon_variant | 0.46 | capreomycin | |
linezolid | ||||||
rrl | 1475897 | n.2240T>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475898 | n.2241A>G | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475899 | n.2242G>A | non_coding_transcript_exon_variant | 0.71 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475900 | n.2243A>G | non_coding_transcript_exon_variant | 0.43 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475906 | n.2249C>T | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475916 | n.2259C>G | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475938 | n.2281C>A | non_coding_transcript_exon_variant | 0.58 | capreomycin | |
linezolid | ||||||
rrl | 1476225 | n.2568T>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476227 | n.2570C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1476229 | n.2572C>T | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476245 | n.2588C>T | non_coding_transcript_exon_variant | 0.27 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476250 | n.2593C>G | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476257 | n.2600G>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476260 | n.2603A>G | non_coding_transcript_exon_variant | 0.83 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476280 | n.2623A>C | non_coding_transcript_exon_variant | 0.6 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476293 | n.2636C>T | non_coding_transcript_exon_variant | 0.74 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476294 | n.2637A>G | non_coding_transcript_exon_variant | 0.83 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476295 | n.2638C>G | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476296 | n.2639C>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476301 | n.2644A>T | non_coding_transcript_exon_variant | 0.78 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476302 | n.2645G>A | non_coding_transcript_exon_variant | 0.75 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476311 | n.2654G>C | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476312 | n.2655T>C | non_coding_transcript_exon_variant | 0.79 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476313 | n.2656G>A | non_coding_transcript_exon_variant | 0.81 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476332 | n.2675G>C | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476338 | n.2681C>T | non_coding_transcript_exon_variant | 0.57 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476353 | n.2696G>T | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476357 | n.2700T>A | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1476358 | n.2701T>C | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476359 | n.2702C>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1476369 | n.2712C>T | non_coding_transcript_exon_variant | 0.58 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476372 | n.2715T>C | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476382 | n.2725A>G | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476383 | n.2726T>A | non_coding_transcript_exon_variant | 0.53 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476425 | n.2768G>T | non_coding_transcript_exon_variant | 0.61 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476428 | n.2771C>T | non_coding_transcript_exon_variant | 0.76 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476429 | n.2772A>C | non_coding_transcript_exon_variant | 0.73 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476466 | n.2809C>T | non_coding_transcript_exon_variant | 0.31 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476481 | n.2824T>C | non_coding_transcript_exon_variant | 0.86 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476506 | n.2849T>C | non_coding_transcript_exon_variant | 0.66 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476513 | n.2856G>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
rrl | 1476515 | n.2858C>T | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476517 | n.2860C>T | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476523 | n.2866T>C | non_coding_transcript_exon_variant | 0.32 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476524 | n.2867C>A | non_coding_transcript_exon_variant | 0.54 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476525 | n.2868A>G | non_coding_transcript_exon_variant | 0.56 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476530 | n.2873C>T | non_coding_transcript_exon_variant | 0.24 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476536 | n.2879G>A | non_coding_transcript_exon_variant | 0.46 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476538 | n.2881A>G | non_coding_transcript_exon_variant | 0.5 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476539 | n.2882A>G | non_coding_transcript_exon_variant | 0.35 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476540 | n.2883C>G | non_coding_transcript_exon_variant | 0.36 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476542 | n.2885T>C | non_coding_transcript_exon_variant | 0.33 | capreomycin | |
linezolid | ||||||
rrl | 1476567 | n.2910C>T | non_coding_transcript_exon_variant | 0.62 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.44 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476585 | n.2928A>G | non_coding_transcript_exon_variant | 0.4 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>A | non_coding_transcript_exon_variant | 0.36 | capreomycin | |
linezolid | ||||||
rrl | 1476603 | n.2946G>T | non_coding_transcript_exon_variant | 0.38 | capreomycin | |
linezolid | ||||||
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
thyX | 3067966 | c.-21G>A | upstream_gene_variant | 1.0 | para-aminosalicylic_acid | |
thyA | 3073868 | p.Thr202Ala | missense_variant | 1.0 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
whiB7 | 3569065 | c.-386T>C | upstream_gene_variant | 1.0 | streptomycin | Uncertain significance |
amikacin | Uncertain significance | |||||
kanamycin | Uncertain significance | |||||
lpqB | 3623609 | c.1302G>T | synonymous_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | rifampicin | Not assoc w R |
bedaquiline | Uncertain significance | |||||
clpC1 | 4038287 | c.2418C>T | synonymous_variant | 1.0 | pyrazinamide | Not assoc w R |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
gid | 4408156 | p.Leu16Arg | missense_variant | 1.0 | streptomycin | Not assoc w R |