TB-Profiler result

Run: ERR4820335
Summary

Run ID: ERR4820335

Sample name:

Date: 01-04-2023 16:37:28

Number of reads: 1995326

Percentage reads mapped: 80.5

Strain: lineage4.1.2.1

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.99
lineage4.1.2 Euro-American T;H None 0.99
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.78 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6361 c.-941G>A upstream_gene_variant 0.25
gyrA 6362 c.-940T>C upstream_gene_variant 0.25
gyrA 6376 c.-926G>A upstream_gene_variant 0.18
gyrA 6379 c.-923C>G upstream_gene_variant 0.16
gyrA 6382 c.-920A>G upstream_gene_variant 0.16
gyrA 6388 c.-914T>C upstream_gene_variant 0.15
gyrA 6403 c.-899T>C upstream_gene_variant 0.16
gyrB 7124 p.Ser629Thr missense_variant 0.14
gyrA 7129 c.-173T>C upstream_gene_variant 0.14
gyrA 7132 c.-170T>G upstream_gene_variant 0.14
gyrA 7141 c.-161T>C upstream_gene_variant 0.24
gyrA 7165 c.-137C>G upstream_gene_variant 0.19
gyrA 7178 c.-124T>C upstream_gene_variant 0.17
gyrA 7186 c.-116C>G upstream_gene_variant 0.15
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7406 c.105G>C synonymous_variant 0.14
gyrA 7427 c.126G>C synonymous_variant 0.14
gyrA 7451 c.150C>G synonymous_variant 0.13
gyrA 7457 c.156T>C synonymous_variant 0.2
gyrA 7475 c.174A>G synonymous_variant 0.14
gyrA 7480 p.Phe60Tyr missense_variant 0.15
gyrA 7484 c.183T>C synonymous_variant 0.16
gyrA 7514 c.213C>G synonymous_variant 0.23
gyrA 7523 c.222C>A synonymous_variant 0.23
gyrA 7532 c.231T>C synonymous_variant 0.22
gyrA 7541 c.240C>G synonymous_variant 0.22
gyrA 7547 c.246C>T synonymous_variant 0.21
gyrA 7562 c.261C>T synonymous_variant 0.14
gyrA 7571 c.270G>C synonymous_variant 0.15
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8588 c.1287G>A synonymous_variant 0.16
gyrA 8603 c.1302A>G synonymous_variant 0.17
gyrA 8619 c.1318T>C synonymous_variant 0.19
gyrA 8624 c.1323G>C synonymous_variant 0.21
gyrA 8636 c.1335A>C synonymous_variant 0.21
gyrA 8642 c.1341A>G synonymous_variant 0.21
gyrA 8762 c.1461G>C synonymous_variant 0.14
gyrA 8767 p.Arg489Lys missense_variant 0.14
gyrA 8780 p.Asp493Glu missense_variant 0.12
gyrA 8801 c.1500G>C synonymous_variant 0.2
gyrA 8807 c.1506C>T synonymous_variant 0.18
gyrA 8810 c.1509A>G synonymous_variant 0.2
gyrA 8816 c.1515C>G synonymous_variant 0.2
gyrA 8818 p.Ser506Asn missense_variant 0.2
gyrA 8828 c.1527T>C synonymous_variant 0.21
gyrA 8829 c.1528T>C synonymous_variant 0.24
gyrA 8852 c.1551T>C synonymous_variant 0.26
gyrA 8867 c.1566A>G synonymous_variant 0.22
gyrA 8870 c.1569G>C synonymous_variant 0.23
gyrA 8873 c.1572A>C synonymous_variant 0.23
gyrA 8891 c.1590G>A synonymous_variant 0.24
gyrA 8897 c.1596T>C synonymous_variant 0.23
gyrA 8903 c.1602T>C synonymous_variant 0.24
gyrA 8933 c.1632G>C synonymous_variant 0.19
gyrA 8946 c.1645T>C synonymous_variant 0.14
gyrA 9089 c.1788G>C synonymous_variant 0.16
gyrA 9104 c.1803C>G synonymous_variant 0.14
gyrA 9119 c.1818A>G synonymous_variant 0.15
gyrA 9122 c.1821C>A synonymous_variant 0.14
gyrA 9143 c.1842T>C synonymous_variant 0.16
gyrA 9153 p.Thr618Glu missense_variant 0.14
gyrA 9158 c.1857C>T synonymous_variant 0.16
gyrA 9161 c.1860C>G synonymous_variant 0.14
gyrA 9191 c.1890G>C synonymous_variant 0.14
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491313 c.531C>G synonymous_variant 0.13
fgd1 491591 p.Lys270Met missense_variant 0.91
fgd1 491620 p.Ile280Val missense_variant 0.12
mshA 575679 p.Asn111Ser missense_variant 0.96
mshA 575845 c.498C>T synonymous_variant 0.13
mshA 575884 c.537G>C synonymous_variant 0.2
mshA 575887 c.540G>C synonymous_variant 0.21
mshA 575893 c.546C>G synonymous_variant 0.21
mshA 575896 c.549G>C synonymous_variant 0.2
mshA 575908 c.561A>G synonymous_variant 0.16
mshA 575917 p.Asp190Glu missense_variant 0.17
mshA 575920 c.573C>G synonymous_variant 0.16
mshA 575924 p.Gly193Ser missense_variant 0.16
ccsA 619699 c.-192G>C upstream_gene_variant 0.13
rpoB 760112 c.306T>C synonymous_variant 0.14
rpoB 760115 c.309C>T synonymous_variant 0.86
rpoB 760118 c.312T>G synonymous_variant 0.14
rpoB 760121 c.315T>C synonymous_variant 0.14
rpoB 760130 p.Asp108Glu missense_variant 0.14
rpoB 760139 c.333A>G synonymous_variant 0.13
rpoB 760142 c.336C>G synonymous_variant 0.14
rpoB 760283 c.477G>C synonymous_variant 0.17
rpoB 760298 c.492G>C synonymous_variant 0.17
rpoB 760307 c.501T>C synonymous_variant 0.13
rpoB 760310 c.504G>C synonymous_variant 0.13
rpoB 760328 c.522G>C synonymous_variant 0.17
rpoB 760331 c.525G>C synonymous_variant 0.17
rpoB 760340 c.534G>T synonymous_variant 0.18
rpoB 760406 c.600G>C synonymous_variant 0.15
rpoB 760412 c.606C>G synonymous_variant 0.17
rpoB 760655 c.849A>G synonymous_variant 0.13
rpoB 760661 c.855A>C synonymous_variant 0.15
rpoB 760718 c.912C>T synonymous_variant 0.17
rpoB 760724 c.918T>C synonymous_variant 0.17
rpoB 760730 c.924T>C synonymous_variant 0.16
rpoB 760751 c.945G>C synonymous_variant 0.14
rpoB 760925 c.1119T>C synonymous_variant 0.13
rpoB 760928 c.1122G>C synonymous_variant 0.14
rpoB 760931 c.1125C>G synonymous_variant 0.13
rpoB 760934 c.1128C>T synonymous_variant 0.14
rpoB 760946 c.1140A>G synonymous_variant 0.24
rpoB 760982 c.1176G>C synonymous_variant 0.31
rpoB 760985 c.1179G>C synonymous_variant 0.24
rpoB 760991 c.1185G>C synonymous_variant 0.23
rpoB 761006 c.1200C>G synonymous_variant 0.18
rpoB 761015 c.1209G>C synonymous_variant 0.18
rpoB 761021 c.1215G>C synonymous_variant 0.17
rpoB 761027 c.1221A>G synonymous_variant 0.15
rpoB 761036 c.1230G>C synonymous_variant 0.15
rpoB 761037 c.1231T>C synonymous_variant 0.16
rpoB 761180 c.1374A>C synonymous_variant 0.14
rpoB 761189 c.1383T>C synonymous_variant 0.19
rpoB 761195 c.1389G>C synonymous_variant 0.16
rpoB 761207 c.1401C>T synonymous_variant 0.2
rpoB 761213 c.1407G>C synonymous_variant 0.25
rpoB 761219 c.1413G>C synonymous_variant 0.23
rpoB 761249 c.1443A>G synonymous_variant 0.26
rpoB 761255 c.1449T>G synonymous_variant 0.2
rpoB 761261 c.1455G>T synonymous_variant 0.27
rpoB 761306 c.1500C>G synonymous_variant 0.17
rpoB 761312 c.1506G>C synonymous_variant 0.18
rpoB 761570 c.1764T>C synonymous_variant 0.13
rpoB 761573 c.1767C>G synonymous_variant 0.13
rpoB 761579 c.1773G>C synonymous_variant 0.16
rpoB 761588 c.1782C>T synonymous_variant 0.17
rpoB 761606 c.1800C>G synonymous_variant 0.18
rpoB 761612 c.1806G>C synonymous_variant 0.18
rpoB 761615 c.1809A>C synonymous_variant 0.19
rpoB 761636 c.1830G>T synonymous_variant 0.21
rpoB 761657 c.1851C>G synonymous_variant 0.13
rpoB 761885 c.2079T>C synonymous_variant 0.15
rpoB 761906 c.2100C>G synonymous_variant 0.14
rpoB 761909 c.2103T>C synonymous_variant 0.13
rpoB 761912 c.2106T>C synonymous_variant 0.14
rpoB 761915 p.Asp703Glu missense_variant 0.14
rpoB 761916 p.Asp704Asn missense_variant 0.15
rpoB 761948 c.2142G>C synonymous_variant 0.15
rpoB 762008 c.2202C>T synonymous_variant 0.36
rpoB 762014 c.2208C>T synonymous_variant 0.37
rpoB 762017 c.2211A>G synonymous_variant 0.35
rpoB 762053 c.2247T>C synonymous_variant 0.23
rpoB 762062 c.2256T>C synonymous_variant 0.19
rpoB 762065 c.2259T>C synonymous_variant 0.19
rpoB 762083 c.2277T>C synonymous_variant 0.14
rpoB 762086 c.2280G>C synonymous_variant 0.14
rpoB 762101 c.2295C>G synonymous_variant 0.14
rpoB 762114 p.Ile770Val missense_variant 0.14
rpoB 762143 c.2337T>C synonymous_variant 0.14
rpoB 762149 c.2343G>C synonymous_variant 0.14
rpoB 762167 c.2361T>C synonymous_variant 0.19
rpoB 762176 c.2370T>C synonymous_variant 0.15
rpoB 762185 c.2379G>C synonymous_variant 0.14
rpoB 762206 c.2400C>G synonymous_variant 0.15
rpoB 762233 c.2427G>C synonymous_variant 0.18
rpoB 762293 c.2487T>C synonymous_variant 0.16
rpoC 762929 c.-441G>C upstream_gene_variant 0.12
rpoC 762989 c.-381G>C upstream_gene_variant 0.17
rpoC 762995 c.-375G>T upstream_gene_variant 0.19
rpoC 763013 c.-357C>G upstream_gene_variant 0.21
rpoC 763025 c.-345C>T upstream_gene_variant 0.2
rpoC 763028 c.-342T>C upstream_gene_variant 0.15
rpoC 763031 c.-339T>G upstream_gene_variant 0.15
rpoC 763040 c.-330C>G upstream_gene_variant 0.13
rpoC 763085 c.-285C>G upstream_gene_variant 0.12
rpoC 763456 c.87A>G synonymous_variant 0.14
rpoC 763486 c.117T>G synonymous_variant 0.2
rpoC 763528 c.159G>A synonymous_variant 0.28
rpoC 763546 c.177A>G synonymous_variant 0.42
rpoC 763570 c.201G>C synonymous_variant 0.21
rpoC 763573 c.204G>C synonymous_variant 0.26
rpoC 763594 c.225C>T synonymous_variant 0.19
rpoC 763603 c.234C>T synonymous_variant 0.17
rpoC 763636 c.267T>C synonymous_variant 0.18
rpoC 763660 c.291T>G synonymous_variant 0.15
rpoC 763675 c.306C>G synonymous_variant 0.12
rpoC 763872 p.Gly168Ala missense_variant 0.13
rpoC 764040 p.Ser224Thr missense_variant 0.14
rpoC 764044 c.675T>C synonymous_variant 0.15
rpoC 764059 c.690G>T synonymous_variant 0.17
rpoC 764083 c.714A>G synonymous_variant 0.18
rpoC 764098 c.729A>G synonymous_variant 0.12
rpoC 764112 p.Tyr248Phe missense_variant 0.12
rpoC 764116 c.747C>T synonymous_variant 0.13
rpoC 764140 c.771C>T synonymous_variant 0.15
rpoC 764560 c.1191T>C synonymous_variant 0.13
rpoC 764566 c.1197C>G synonymous_variant 0.14
rpoC 764575 c.1206T>G synonymous_variant 0.14
rpoC 764764 c.1395T>C synonymous_variant 0.14
rpoC 765150 p.Gly594Glu missense_variant 0.97
rpoC 765292 c.1923G>C synonymous_variant 0.12
rpoC 765298 c.1929G>C synonymous_variant 0.13
rpoC 765346 c.1977C>G synonymous_variant 0.14
rpoC 765349 c.1980T>C synonymous_variant 0.13
rpoC 765352 c.1983G>C synonymous_variant 0.13
rpoC 765404 p.Leu679Val missense_variant 0.22
rpoC 765409 c.2040T>C synonymous_variant 0.21
rpoC 765421 c.2052C>G synonymous_variant 0.24
rpoC 765499 c.2130C>G synonymous_variant 0.13
rpoC 765529 c.2160C>T synonymous_variant 0.15
rpoC 765541 c.2172C>G synonymous_variant 0.13
rpoC 765553 c.2184C>T synonymous_variant 0.15
rpoC 765556 c.2187G>C synonymous_variant 0.15
rpoC 765559 c.2190G>C synonymous_variant 0.15
rpoC 765580 c.2211G>C synonymous_variant 0.21
rpoC 765625 c.2256C>G synonymous_variant 0.14
rpoC 765631 p.Asp754Glu missense_variant 0.12
rpoC 765967 c.2598C>T synonymous_variant 0.19
rpoC 765982 c.2613C>G synonymous_variant 0.18
rpoC 765994 c.2625A>T synonymous_variant 0.19
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.15
rpoC 766021 c.2652G>C synonymous_variant 0.16
rpoC 766027 c.2658G>C synonymous_variant 0.16
rpoC 766030 c.2661C>G synonymous_variant 0.15
rpoC 766043 p.Gln892Glu missense_variant 0.16
rpoC 766083 p.Ala905Glu missense_variant 0.12
rpoC 766096 c.2727G>C synonymous_variant 0.15
rpoC 766426 c.3057C>T synonymous_variant 0.12
rpoC 766447 c.3078T>C synonymous_variant 0.16
rpoC 766462 c.3093G>C synonymous_variant 0.16
rpoC 766738 c.3369G>C synonymous_variant 0.14
rpoC 766765 c.3396A>C synonymous_variant 0.17
rpoC 766774 c.3405T>C synonymous_variant 0.14
rpoC 766801 c.3432C>G synonymous_variant 0.15
rpoC 766804 c.3435A>G synonymous_variant 0.16
rpoC 766876 c.3507C>T synonymous_variant 0.13
rpoC 766882 c.3513C>T synonymous_variant 0.18
rpoC 766894 c.3525T>C synonymous_variant 0.17
rpoC 766895 c.3526T>C synonymous_variant 0.19
rpoC 766900 c.3531T>C synonymous_variant 0.19
rpoC 766933 c.3564A>G synonymous_variant 0.21
rpoC 766945 c.3576A>G synonymous_variant 0.17
rpoC 766963 c.3594T>C synonymous_variant 0.16
rpoC 766972 c.3603G>C synonymous_variant 0.15
rpoC 766996 c.3627C>T synonymous_variant 0.16
rpoC 767009 p.Ser1214Thr missense_variant 0.12
rpoC 767014 c.3645G>C synonymous_variant 0.14
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.14
rpoC 767059 c.3690T>G synonymous_variant 0.16
rpoC 767062 c.3693C>A synonymous_variant 0.16
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781628 c.69T>C synonymous_variant 0.15
rpsL 781631 c.72G>C synonymous_variant 0.15
rpsL 781649 c.90T>C synonymous_variant 0.15
rpsL 781655 c.96T>C synonymous_variant 0.15
rpsL 781760 c.201T>C synonymous_variant 0.13
rpsL 781808 c.249C>T synonymous_variant 0.14
rpsL 781811 c.252C>T synonymous_variant 0.2
rpsL 781838 c.279G>C synonymous_variant 0.15
rpsL 781841 c.282C>G synonymous_variant 0.15
rpsL 781877 c.318T>C synonymous_variant 0.15
rpsL 781892 c.333A>G synonymous_variant 0.16
rplC 800648 c.-161A>T upstream_gene_variant 0.13
rplC 800693 c.-116A>G upstream_gene_variant 0.16
rplC 800720 c.-89T>C upstream_gene_variant 0.13
fbiC 1303846 p.Phe306Val missense_variant 0.14
fbiC 1303854 c.924T>C synonymous_variant 0.13
fbiC 1304778 c.1848T>C synonymous_variant 0.15
fbiC 1304784 c.1854T>C synonymous_variant 0.13
fbiC 1304787 c.1857T>G synonymous_variant 0.12
fbiC 1304808 c.1878C>G synonymous_variant 0.19
fbiC 1304811 c.1881C>G synonymous_variant 0.2
fbiC 1304817 c.1887T>C synonymous_variant 0.26
fbiC 1304829 c.1899T>C synonymous_variant 0.33
fbiC 1304832 c.1902C>T synonymous_variant 0.32
fbiC 1304856 c.1926C>G synonymous_variant 0.55
fbiC 1304862 c.1932G>A synonymous_variant 0.24
fbiC 1304869 c.1939C>T synonymous_variant 0.21
fbiC 1304875 p.Ile649Val missense_variant 0.22
fbiC 1304883 p.Glu651Asp missense_variant 0.22
fbiC 1304891 p.Ile654Thr missense_variant 0.2
fbiC 1304893 p.Gly655Ser missense_variant 0.2
fbiC 1304910 c.1980G>C synonymous_variant 0.13
fbiC 1304916 c.1986T>C synonymous_variant 0.14
fbiC 1304928 c.1998T>C synonymous_variant 0.15
fbiC 1304937 c.2007G>C synonymous_variant 0.14
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.13
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.13
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.19
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.13
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.25
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.29
rrs 1472108 n.263C>A non_coding_transcript_exon_variant 0.4
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.15
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.15
rrs 1472130 n.285G>A non_coding_transcript_exon_variant 0.15
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.15
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.38
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.15
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.14
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.33
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.4
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.5
rrs 1472507 n.662C>G non_coding_transcript_exon_variant 0.4
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.6
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.5
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.82
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.93
rrs 1472544 n.699C>A non_coding_transcript_exon_variant 0.91
rrs 1472545 n.700A>T non_coding_transcript_exon_variant 0.95
rrs 1472566 n.721G>A non_coding_transcript_exon_variant 0.93
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.9
rrs 1472579 n.734G>C non_coding_transcript_exon_variant 0.9
rrs 1472580 n.735C>T non_coding_transcript_exon_variant 0.87
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.93
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.93
rrs 1472599 n.754G>T non_coding_transcript_exon_variant 0.93
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.95
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.67
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.27
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.86
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.87
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.79
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.82
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.15
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.83
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.16
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.81
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.76
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.86
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.6
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.8
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.75
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.3
rrs 1472954 n.1109T>C non_coding_transcript_exon_variant 0.2
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.3
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.65
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.58
rrs 1472958 n.1113A>G non_coding_transcript_exon_variant 0.2
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.5
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.69
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.47
rrs 1472988 n.1143T>C non_coding_transcript_exon_variant 0.13
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.47
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.73
rrs 1473005 n.1160C>T non_coding_transcript_exon_variant 0.22
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.81
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.73
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.73
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.75
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.64
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.4
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.56
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.38
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.62
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.62
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.62
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.44
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.58
rrs 1473123 n.1278A>T non_coding_transcript_exon_variant 0.33
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.69
rrs 1473147 n.1302G>T non_coding_transcript_exon_variant 0.18
rrs 1473148 n.1303G>T non_coding_transcript_exon_variant 0.22
rrs 1473150 n.1305T>G non_coding_transcript_exon_variant 0.18
rrs 1473161 n.1316A>C non_coding_transcript_exon_variant 0.18
rrs 1473163 n.1318C>A non_coding_transcript_exon_variant 0.25
rrs 1473164 n.1319C>A non_coding_transcript_exon_variant 0.2
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.6
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.18
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.23
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.19
rrs 1473199 n.1356delA non_coding_transcript_exon_variant 0.18
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.22
rrs 1473221 n.1376C>T non_coding_transcript_exon_variant 0.17
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.25
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.25
rrs 1473276 n.1431A>C non_coding_transcript_exon_variant 0.21
rrs 1473277 n.1432G>A non_coding_transcript_exon_variant 0.21
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.36
rrl 1473668 n.11C>T non_coding_transcript_exon_variant 0.14
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.5
rrl 1474228 n.571T>C non_coding_transcript_exon_variant 0.5
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.5
rrl 1474252 n.595T>A non_coding_transcript_exon_variant 0.5
rrl 1474254 n.597C>A non_coding_transcript_exon_variant 0.5
rrl 1474275 n.618T>C non_coding_transcript_exon_variant 0.67
rrl 1474448 n.791T>C non_coding_transcript_exon_variant 1.0
rrl 1474467 n.810A>G non_coding_transcript_exon_variant 1.0
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.6
rrl 1474495 n.838G>A non_coding_transcript_exon_variant 0.5
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 0.5
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 0.5
rrl 1474508 n.851C>T non_coding_transcript_exon_variant 0.6
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.67
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.67
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.67
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.6
rrl 1474774 n.1117A>G non_coding_transcript_exon_variant 1.0
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 1.0
rrl 1474824 n.1167A>G non_coding_transcript_exon_variant 1.0
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 1.0
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 1.0
rrl 1475900 n.2243A>G non_coding_transcript_exon_variant 0.22
rrl 1475902 n.2245T>C non_coding_transcript_exon_variant 0.22
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.22
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 0.2
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 0.18
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.22
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.4
rrl 1476227 n.2570C>T non_coding_transcript_exon_variant 0.4
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.5
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.5
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.67
rrl 1476252 n.2595T>A non_coding_transcript_exon_variant 0.4
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.5
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 1.0
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.4
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.47
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.58
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.68
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.53
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.38
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.29
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.3
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.4
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.33
inhA 1673961 c.-241A>C upstream_gene_variant 0.14
rpsA 1833554 p.Thr5Ala missense_variant 0.15
rpsA 1833568 c.27G>C synonymous_variant 0.15
rpsA 1833589 c.48A>T synonymous_variant 0.17
rpsA 1833595 c.54T>C synonymous_variant 0.16
rpsA 1833721 c.180A>G synonymous_variant 0.16
rpsA 1833724 c.183C>G synonymous_variant 0.17
rpsA 1833727 c.186G>C synonymous_variant 0.2
rpsA 1833742 c.201A>G synonymous_variant 0.17
rpsA 1833745 c.204G>C synonymous_variant 0.17
rpsA 1833748 c.207C>G synonymous_variant 0.17
rpsA 1833787 c.246C>G synonymous_variant 0.2
rpsA 1833790 c.249T>C synonymous_variant 0.18
rpsA 1833802 c.261A>G synonymous_variant 0.16
rpsA 1833811 c.270G>T synonymous_variant 0.17
rpsA 1833847 c.306C>G synonymous_variant 0.13
rpsA 1833874 c.333T>C synonymous_variant 0.14
rpsA 1833886 c.345C>G synonymous_variant 0.14
rpsA 1833928 c.387G>C synonymous_variant 0.15
rpsA 1834210 c.669C>T synonymous_variant 0.13
rpsA 1834222 c.681T>C synonymous_variant 0.15
rpsA 1834609 c.1068T>C synonymous_variant 0.2
rpsA 1834618 c.1077G>C synonymous_variant 0.18
rpsA 1834633 c.1092A>G synonymous_variant 0.17
rpsA 1834639 c.1098T>C synonymous_variant 0.17
rpsA 1834654 p.Glu371Asp missense_variant 0.15
rpsA 1834775 p.Ala412Thr missense_variant 0.14
rpsA 1834780 c.1239A>G synonymous_variant 0.14
rpsA 1834786 c.1245A>G synonymous_variant 0.14
rpsA 1834789 c.1248T>C synonymous_variant 0.14
rpsA 1834792 c.1251G>C synonymous_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2517950 c.-165C>G upstream_gene_variant 0.17
kasA 2517989 c.-126T>C upstream_gene_variant 0.15
kasA 2517993 c.-122G>T upstream_gene_variant 0.14
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
kasA 2518480 c.366T>C synonymous_variant 0.16
kasA 2518483 c.369C>G synonymous_variant 0.15
kasA 2518504 c.390T>C synonymous_variant 0.18
kasA 2518506 p.Ala131Glu missense_variant 0.19
kasA 2518519 c.405G>C synonymous_variant 0.18
kasA 2518528 c.414C>G synonymous_variant 0.27
kasA 2518540 c.426T>C synonymous_variant 0.26
kasA 2518561 c.447T>C synonymous_variant 0.18
kasA 2518567 c.453G>C synonymous_variant 0.17
kasA 2518570 c.456G>C synonymous_variant 0.17
kasA 2518574 p.Ile154Val missense_variant 0.16
kasA 2518579 c.465T>C synonymous_variant 0.15
kasA 2518609 p.Met165Ile missense_variant 0.13
kasA 2518744 c.630C>T synonymous_variant 0.15
kasA 2518747 c.633C>G synonymous_variant 0.15
kasA 2518768 c.654C>T synonymous_variant 0.24
kasA 2518777 c.663C>T synonymous_variant 0.24
kasA 2518783 c.669T>C synonymous_variant 0.23
kasA 2518789 c.675G>C synonymous_variant 0.21
kasA 2518792 c.678C>A synonymous_variant 0.2
kasA 2518795 c.681C>G synonymous_variant 0.21
kasA 2518825 c.711T>C synonymous_variant 0.16
Rv2752c 3065946 p.Gly82Ala missense_variant 0.17
Rv2752c 3065955 c.235_237delTTGinsCTC synonymous_variant 0.13
Rv2752c 3065979 c.213T>C synonymous_variant 0.14
thyX 3067391 c.555G>C synonymous_variant 0.13
thyX 3067394 c.552G>C synonymous_variant 0.13
thyX 3067457 c.489C>G synonymous_variant 0.13
thyX 3067465 p.Ile161Val missense_variant 0.12
thyX 3067691 p.Ile85Met missense_variant 0.14
thyX 3067694 c.252G>C synonymous_variant 0.13
thyX 3067718 c.228C>G synonymous_variant 0.16
thyX 3067721 c.225T>C synonymous_variant 0.14
thyX 3067814 c.132T>C synonymous_variant 0.13
thyX 3067850 c.96A>C synonymous_variant 0.2
thyX 3067869 p.Thr26Ser missense_variant 0.23
thyX 3067874 c.72C>G synonymous_variant 0.22
thyX 3067883 c.63C>G synonymous_variant 0.23
thyX 3067886 c.60A>C synonymous_variant 0.21
thyX 3067889 c.57C>G synonymous_variant 0.22
thyX 3067898 p.Asp16Glu missense_variant 0.18
thyX 3067935 p.Thr4Ile missense_variant 0.14
thyA 3073953 c.519T>C synonymous_variant 0.15
thyA 3073956 c.516G>C synonymous_variant 0.15
thyA 3073959 c.513T>C synonymous_variant 0.14
thyA 3073977 c.495A>G synonymous_variant 0.17
thyA 3073989 c.483T>C synonymous_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473809 c.-198G>C upstream_gene_variant 0.13
fprA 3473812 c.-195G>A upstream_gene_variant 0.16
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiA 3640612 p.Gly24Ser missense_variant 1.0
rpoA 3877553 p.Glu319Gln missense_variant 0.15
rpoA 3877571 p.Pro313Ala missense_variant 0.17
rpoA 3877587 c.921A>G synonymous_variant 0.14
rpoA 3877613 p.Ile299Val missense_variant 0.14
rpoA 3877679 p.Ala277Ser missense_variant 0.16
rpoA 3877686 c.822A>G synonymous_variant 0.14
rpoA 3877692 c.816G>C synonymous_variant 0.16
rpoA 3877704 c.804G>C synonymous_variant 0.15
rpoA 3878082 c.426T>G synonymous_variant 0.12
rpoA 3878346 c.162T>C synonymous_variant 0.13
rpoA 3878388 c.120C>G synonymous_variant 0.14
rpoA 3878391 c.117T>C synonymous_variant 0.14
rpoA 3878415 c.93C>T synonymous_variant 0.14
ddn 3987001 p.Gly53Asp missense_variant 1.0
clpC1 4039169 p.Glu512Asp missense_variant 0.13
clpC1 4039172 c.1533A>G synonymous_variant 0.13
clpC1 4039178 c.1527G>C synonymous_variant 0.14
clpC1 4039186 c.1519C>T synonymous_variant 0.15
clpC1 4039226 c.1479T>C synonymous_variant 0.16
clpC1 4039229 c.1476C>G synonymous_variant 0.16
clpC1 4039274 c.1431G>C synonymous_variant 0.14
clpC1 4039430 c.1275T>C synonymous_variant 0.16
clpC1 4039442 c.1263A>G synonymous_variant 0.14
clpC1 4039454 c.1251A>G synonymous_variant 0.15
clpC1 4039463 c.1242C>G synonymous_variant 0.21
clpC1 4039466 c.1239T>C synonymous_variant 0.17
clpC1 4039469 c.1236T>C synonymous_variant 0.18
clpC1 4039480 c.1225C>A synonymous_variant 0.15
clpC1 4039481 c.1224T>G synonymous_variant 0.15
clpC1 4039517 c.1188C>G synonymous_variant 0.15
clpC1 4039661 c.1044T>G synonymous_variant 0.15
clpC1 4039664 c.1041G>C synonymous_variant 0.15
clpC1 4039724 c.981A>G synonymous_variant 0.16
clpC1 4040171 c.534C>G synonymous_variant 0.12
clpC1 4040246 c.459C>G synonymous_variant 0.16
clpC1 4040249 c.456A>G synonymous_variant 0.16
clpC1 4040267 c.438A>G synonymous_variant 0.15
clpC1 4040277 c.427_428delTCinsAG synonymous_variant 0.13
embC 4241146 c.1284C>G synonymous_variant 0.13
embC 4241158 c.1296T>C synonymous_variant 0.13
embC 4241161 c.1299C>G synonymous_variant 0.13
embC 4241162 c.1300T>C synonymous_variant 0.13
embC 4241170 c.1308G>C synonymous_variant 0.15
embC 4241203 c.1341T>C synonymous_variant 0.15
embC 4241206 c.1344G>C synonymous_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.85
embA 4242820 c.-413G>C upstream_gene_variant 0.15
embA 4245083 c.1851A>C synonymous_variant 0.15
embA 4245089 c.1857G>C synonymous_variant 0.16
embA 4245092 c.1860C>G synonymous_variant 0.15
embA 4245101 c.1869G>C synonymous_variant 0.16
embB 4247539 c.1026T>C synonymous_variant 0.13
embB 4248097 c.1584C>G synonymous_variant 0.14
embB 4248130 c.1617G>C synonymous_variant 0.17
embB 4248133 c.1620C>G synonymous_variant 0.16
embB 4248139 c.1626C>G synonymous_variant 0.16
embB 4248142 c.1629T>C synonymous_variant 0.16
embB 4248143 c.1630T>C synonymous_variant 0.16
embB 4248157 c.1644A>G synonymous_variant 0.15
embB 4248373 c.1860C>G synonymous_variant 0.14
embB 4248386 c.1873C>A synonymous_variant 0.15
embB 4248407 p.Leu632Val missense_variant 0.13
embB 4248457 c.1944T>C synonymous_variant 0.19
whiB6 4338595 c.-75delG upstream_gene_variant 1.0