TB-Profiler result

Run: SRR13861153
Summary

Run ID: SRR13861153

Sample name:

Date: 03-04-2023 09:24:51

Number of reads: 1123950

Percentage reads mapped: 37.5

Strain: lineage4.9

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
embB 4247448 p.His312Arg missense_variant 0.15 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6280 c.1041T>C synonymous_variant 0.24
gyrB 6286 c.1047T>C synonymous_variant 0.24
gyrB 6292 c.1053G>C synonymous_variant 0.22
gyrB 6295 c.1056A>G synonymous_variant 0.21
gyrB 6298 c.1059C>T synonymous_variant 0.21
gyrB 6299 c.1060C>T synonymous_variant 0.22
gyrA 6307 c.-995T>G upstream_gene_variant 0.22
gyrA 6319 c.-983G>C upstream_gene_variant 0.2
gyrA 6325 c.-977C>G upstream_gene_variant 0.2
gyrA 6361 c.-941G>A upstream_gene_variant 0.14
gyrA 6379 c.-923C>G upstream_gene_variant 0.15
gyrA 6388 c.-914T>C upstream_gene_variant 0.15
gyrA 7799 c.498A>G synonymous_variant 0.17
gyrA 7835 c.534A>G synonymous_variant 0.15
gyrA 7838 c.537C>G synonymous_variant 0.16
gyrA 8069 c.768T>C synonymous_variant 0.15
gyrA 8111 c.810G>C synonymous_variant 0.17
gyrA 8156 c.855T>C synonymous_variant 0.16
gyrA 8168 c.867A>G synonymous_variant 0.18
gyrA 8174 c.873C>G synonymous_variant 0.18
gyrA 8177 c.876A>C synonymous_variant 0.2
gyrA 8198 c.897T>C synonymous_variant 0.22
gyrA 8204 c.903C>T synonymous_variant 0.22
gyrA 8207 c.906T>C synonymous_variant 0.22
gyrA 8216 c.915G>A synonymous_variant 0.21
gyrA 8219 c.918T>C synonymous_variant 0.2
gyrA 8225 c.924T>C synonymous_variant 0.19
gyrA 8234 c.933T>G synonymous_variant 0.19
gyrA 8235 c.934_936delTTAinsCTG synonymous_variant 0.18
gyrA 8253 p.Ile318Leu missense_variant 0.2
gyrA 8264 c.963T>C synonymous_variant 0.18
gyrA 8267 c.966G>C synonymous_variant 0.18
gyrA 8270 c.969G>C synonymous_variant 0.19
gyrA 8283 p.Ile328Leu missense_variant 0.16
gyrA 8288 c.987T>C synonymous_variant 0.16
gyrA 8294 c.993T>C synonymous_variant 0.16
gyrA 8324 c.1023T>C synonymous_variant 0.16
gyrA 8987 c.1686C>G synonymous_variant 0.15
gyrA 8990 c.1689C>G synonymous_variant 0.14
gyrA 9252 p.Val651Ile missense_variant 0.13
gyrA 9275 c.1974G>A synonymous_variant 0.16
gyrA 9278 c.1977G>C synonymous_variant 0.15
gyrA 9281 c.1980C>G synonymous_variant 0.14
gyrA 9291 c.1990C>T synonymous_variant 0.15
gyrA 9296 c.1995T>C synonymous_variant 0.14
fgd1 491043 c.261T>A synonymous_variant 0.18
fgd1 491049 c.267T>C synonymous_variant 0.16
fgd1 491063 p.Gly94Ala missense_variant 0.17
fgd1 491077 p.Asn99Gly missense_variant 0.17
fgd1 491082 c.300T>C synonymous_variant 0.17
fgd1 491083 p.Val101Ile missense_variant 0.14
fgd1 491091 c.309T>C synonymous_variant 0.17
fgd1 491094 c.312C>G synonymous_variant 0.16
fgd1 491106 c.324T>C synonymous_variant 0.16
fgd1 491121 c.339A>G synonymous_variant 0.21
fgd1 491137 p.Glu119Gln missense_variant 0.2
fgd1 491144 p.Ala121Glu missense_variant 0.2
fgd1 491166 c.384G>C synonymous_variant 0.17
fgd1 491181 c.399T>C synonymous_variant 0.14
mshA 575623 c.276C>G synonymous_variant 0.16
mshA 575638 c.291T>C synonymous_variant 0.15
mshA 575641 c.294A>G synonymous_variant 0.15
mshA 575648 p.Val101Gln missense_variant 0.17
mshA 575659 c.312A>G synonymous_variant 0.22
mshA 575665 c.318G>C synonymous_variant 0.26
mshA 575689 c.342G>C synonymous_variant 0.19
mshA 575695 c.348C>G synonymous_variant 0.19
mshA 575704 c.357T>C synonymous_variant 0.17
mshA 575705 c.358T>C synonymous_variant 0.17
mshA 575713 c.366G>A synonymous_variant 0.18
mshA 575719 c.372C>T synonymous_variant 0.19
mshA 575734 c.387T>G synonymous_variant 0.18
mshA 575737 c.390T>C synonymous_variant 0.19
mshA 575746 c.399C>G synonymous_variant 0.22
mshA 575752 c.405G>A synonymous_variant 0.21
mshA 575767 c.420G>A synonymous_variant 0.19
mshA 575771 p.Val142Ser missense_variant 0.19
mshA 575779 c.432A>G synonymous_variant 0.18
ccsA 620257 p.Ile123Val missense_variant 0.14
ccsA 620269 p.Val127Ile missense_variant 0.14
ccsA 620283 c.393T>C synonymous_variant 0.13
ccsA 620288 p.Arg133Gln missense_variant 0.14
ccsA 620661 c.771C>G synonymous_variant 0.16
ccsA 620703 c.813G>C synonymous_variant 0.21
ccsA 620710 p.Val274Ile missense_variant 0.2
ccsA 620718 c.828G>C synonymous_variant 0.2
ccsA 620721 c.831G>C synonymous_variant 0.2
ccsA 620730 c.840C>T synonymous_variant 0.2
ccsA 620733 c.843G>C synonymous_variant 0.2
ccsA 620734 c.844C>A synonymous_variant 0.2
ccsA 620739 c.849A>G synonymous_variant 0.2
ccsA 620745 c.855G>C synonymous_variant 0.19
ccsA 620748 c.858T>A synonymous_variant 0.18
ccsA 620778 c.888T>C synonymous_variant 0.18
ccsA 620784 c.894C>G synonymous_variant 0.17
ccsA 620787 c.897C>G synonymous_variant 0.16
rpoB 760181 c.375T>C synonymous_variant 0.15
rpoB 760184 c.378A>G synonymous_variant 0.15
rpoB 760196 c.390C>G synonymous_variant 0.16
rpoB 760223 c.417T>C synonymous_variant 0.18
rpoB 760235 c.429T>C synonymous_variant 0.17
rpoB 760283 c.477G>C synonymous_variant 0.21
rpoB 760307 c.501T>C synonymous_variant 0.18
rpoB 760328 c.522G>C synonymous_variant 0.18
rpoB 760331 c.525G>C synonymous_variant 0.17
rpoB 760337 c.531C>G synonymous_variant 0.18
rpoB 760340 c.534G>C synonymous_variant 0.17
rpoB 760361 c.555T>C synonymous_variant 0.17
rpoB 760376 p.Asp190Glu missense_variant 0.14
rpoB 760406 c.600G>C synonymous_variant 0.17
rpoB 760418 c.612G>C synonymous_variant 0.17
rpoB 760475 c.669A>G synonymous_variant 0.19
rpoB 760481 c.675G>C synonymous_variant 0.19
rpoB 760484 c.678A>G synonymous_variant 0.21
rpoB 760514 c.708C>T synonymous_variant 0.19
rpoB 760522 p.Ser239Asn missense_variant 0.2
rpoB 760532 c.726T>C synonymous_variant 0.18
rpoB 760533 p.Val243Thr missense_variant 0.18
rpoB 760547 c.741G>C synonymous_variant 0.16
rpoB 760563 p.Arg253Met missense_variant 0.15
rpoB 760919 c.1113C>G synonymous_variant 0.17
rpoB 760925 c.1119T>C synonymous_variant 0.18
rpoB 760928 c.1122G>C synonymous_variant 0.16
rpoB 760934 c.1128C>T synonymous_variant 0.18
rpoB 760946 c.1140A>G synonymous_variant 0.17
rpoB 760982 c.1176G>C synonymous_variant 0.15
rpoB 760985 c.1179G>C synonymous_variant 0.15
rpoB 761015 c.1209G>C synonymous_variant 0.17
rpoB 761021 c.1215G>C synonymous_variant 0.17
rpoB 761362 p.Ser519Thr missense_variant 0.15
rpoB 761612 c.1806G>C synonymous_variant 0.14
rpoB 761657 c.1851C>G synonymous_variant 0.18
rpoB 761675 c.1869G>C synonymous_variant 0.16
rpoB 761687 c.1881C>T synonymous_variant 0.14
rpoB 761778 p.Asn658Asp missense_variant 0.14
rpoB 761847 p.Cys681Ser missense_variant 0.13
rpoB 761858 c.2052G>C synonymous_variant 0.15
rpoB 761873 c.2067A>G synonymous_variant 0.15
rpoB 761885 c.2079T>C synonymous_variant 0.16
rpoB 761891 c.2085G>C synonymous_variant 0.18
rpoB 761906 c.2100C>G synonymous_variant 0.16
rpoB 761909 c.2103T>C synonymous_variant 0.16
rpoB 761912 c.2106T>C synonymous_variant 0.16
rpoB 761915 p.Asp703Glu missense_variant 0.16
rpoB 761916 p.Asp704Asn missense_variant 0.15
rpoB 761948 c.2142G>C synonymous_variant 0.14
rpoB 762008 c.2202C>G synonymous_variant 0.14
rpoB 762014 c.2208C>T synonymous_variant 0.14
rpoB 762027 c.2221_2223delCTCinsTTG synonymous_variant 0.14
rpoB 762065 c.2259T>C synonymous_variant 0.14
rpoB 762083 c.2277T>C synonymous_variant 0.15
rpoB 762086 c.2280G>C synonymous_variant 0.15
rpoB 762101 c.2295C>G synonymous_variant 0.17
rpoB 762185 c.2379G>C synonymous_variant 0.15
rpoB 762218 c.2412T>G synonymous_variant 0.16
rpoC 762443 c.-927G>C upstream_gene_variant 0.16
rpoC 762470 c.-900G>C upstream_gene_variant 0.18
rpoB 762489 p.Val895Gln missense_variant 0.18
rpoC 762551 c.-819C>T upstream_gene_variant 0.15
rpoC 762989 c.-381G>C upstream_gene_variant 0.17
rpoC 762995 c.-375G>T upstream_gene_variant 0.17
rpoC 763028 c.-342T>C upstream_gene_variant 0.16
rpoC 763031 c.-339T>G upstream_gene_variant 0.16
rpoC 763034 c.-336C>G upstream_gene_variant 0.17
rpoC 763040 c.-330C>G upstream_gene_variant 0.18
rpoC 763070 c.-300T>C upstream_gene_variant 0.15
rpoC 763115 c.-255T>C upstream_gene_variant 0.18
rpoC 763136 c.-234C>T upstream_gene_variant 0.16
rpoC 763158 c.-212C>T upstream_gene_variant 0.14
rpoC 763486 c.117T>C synonymous_variant 0.14
rpoC 763528 c.159G>A synonymous_variant 0.14
rpoC 763570 c.201G>C synonymous_variant 0.17
rpoC 763594 c.225C>T synonymous_variant 0.18
rpoC 763633 c.264T>C synonymous_variant 0.18
rpoC 763636 c.267T>C synonymous_variant 0.17
rpoC 763642 c.273G>C synonymous_variant 0.18
rpoC 763658 c.289_291delCTTinsTTG synonymous_variant 0.15
rpoC 763675 c.306C>G synonymous_variant 0.15
rpoC 763696 c.327T>C synonymous_variant 0.16
rpoC 763702 c.333C>G synonymous_variant 0.16
rpoC 763732 c.363C>G synonymous_variant 0.15
rpoC 763735 c.366G>C synonymous_variant 0.14
rpoC 763744 c.375G>C synonymous_variant 0.14
rpoC 763765 c.396T>C synonymous_variant 0.16
rpoC 763768 c.399C>G synonymous_variant 0.16
rpoC 763780 c.411C>G synonymous_variant 0.16
rpoC 763783 c.414G>C synonymous_variant 0.16
rpoC 763801 c.432C>G synonymous_variant 0.15
rpoC 763807 c.438T>C synonymous_variant 0.15
rpoC 763819 c.450G>C synonymous_variant 0.17
rpoC 763831 c.462A>G synonymous_variant 0.15
rpoC 763835 p.Ala156Met missense_variant 0.15
rpoC 764389 p.Leu340Phe missense_variant 0.14
rpoC 764431 c.1062G>C synonymous_variant 0.17
rpoC 764434 c.1065A>G synonymous_variant 0.18
rpoC 764446 c.1077T>C synonymous_variant 0.16
rpoC 764449 c.1080G>C synonymous_variant 0.17
rpoC 764455 c.1086G>C synonymous_variant 0.15
rpoC 764458 c.1089G>C synonymous_variant 0.15
rpoC 764644 c.1275G>C synonymous_variant 0.15
rpoC 764650 c.1281G>T synonymous_variant 0.15
rpoC 764752 c.1383G>C synonymous_variant 0.13
rpoC 764791 c.1422C>G synonymous_variant 0.14
rpoC 765499 c.2130C>G synonymous_variant 0.14
rpoC 765508 c.2139C>G synonymous_variant 0.16
rpoC 765541 c.2172C>G synonymous_variant 0.15
rpoC 765553 c.2184C>T synonymous_variant 0.14
rpoC 765556 c.2187G>C synonymous_variant 0.14
rpoC 765613 p.His748Gln missense_variant 0.17
rpoC 765625 c.2256C>G synonymous_variant 0.18
rpoC 765628 c.2259G>C synonymous_variant 0.18
rpoC 765631 p.Asp754Glu missense_variant 0.18
rpoC 765700 c.2331T>C synonymous_variant 0.15
rpoC 765734 c.2365T>C synonymous_variant 0.17
rpoC 765739 c.2370G>C synonymous_variant 0.18
rpoC 765772 c.2403C>G synonymous_variant 0.17
rpoC 765784 c.2415C>G synonymous_variant 0.16
rpoC 765796 c.2427C>T synonymous_variant 0.14
rpoC 765811 c.2442T>C synonymous_variant 0.18
rpoC 765814 c.2445A>G synonymous_variant 0.18
rpoC 765826 c.2457T>C synonymous_variant 0.22
rpoC 765835 c.2466C>T synonymous_variant 0.22
rpoC 765883 c.2514C>G synonymous_variant 0.22
rpoC 765886 c.2517C>G synonymous_variant 0.2
rpoC 765892 c.2523T>C synonymous_variant 0.21
rpoC 765928 c.2559C>G synonymous_variant 0.18
rpoC 765967 c.2598C>T synonymous_variant 0.13
rpoC 765970 c.2601C>T synonymous_variant 0.13
rpoC 766010 p.Ser881Thr missense_variant 0.12
rpoC 766408 c.3039C>T synonymous_variant 0.13
rpoC 766426 c.3057C>T synonymous_variant 0.14
rpoC 766522 c.3153C>G synonymous_variant 0.14
rpoC 766528 c.3159T>C synonymous_variant 0.15
rpoC 766531 c.3162G>T synonymous_variant 0.15
rpoC 766543 c.3174C>T synonymous_variant 0.12
rpoC 766549 c.3180G>C synonymous_variant 0.15
rpoC 766645 c.3276A>G synonymous_variant 0.16
rpoC 766738 c.3369G>T synonymous_variant 0.14
rpoC 766963 c.3594T>C synonymous_variant 0.17
rpoC 766978 c.3609C>G synonymous_variant 0.16
rpoC 767009 p.Ser1214Thr missense_variant 0.13
rpoC 767059 c.3690T>G synonymous_variant 0.16
rpoC 767062 c.3693C>A synonymous_variant 0.15
rpoC 767074 c.3705T>C synonymous_variant 0.14
rpoC 767158 c.3789T>C synonymous_variant 0.14
rpsL 781631 c.72G>C synonymous_variant 0.15
rpsL 781649 c.90T>C synonymous_variant 0.14
rpsL 781655 c.96T>C synonymous_variant 0.16
rpsL 781682 c.123T>C synonymous_variant 0.19
rpsL 781728 c.169T>C synonymous_variant 0.15
rpsL 781736 c.177T>C synonymous_variant 0.15
rpsL 781751 c.192G>C synonymous_variant 0.17
rpsL 781754 c.195G>C synonymous_variant 0.18
rpsL 781760 c.201T>C synonymous_variant 0.18
rpsL 781793 c.234G>C synonymous_variant 0.17
rpsL 781859 c.300T>C synonymous_variant 0.16
rpsL 781868 c.309T>C synonymous_variant 0.15
rpsL 781898 c.339A>T synonymous_variant 0.15
rpsL 781929 p.Gly124Ser missense_variant 0.15
rplC 800844 c.36T>C synonymous_variant 0.15
rplC 800865 c.57A>G synonymous_variant 0.2
rplC 800867 p.Ser20Asn missense_variant 0.23
rplC 800874 c.66A>G synonymous_variant 0.21
rplC 800877 c.69A>C synonymous_variant 0.2
rplC 800880 c.72A>G synonymous_variant 0.22
rplC 800889 c.81C>G synonymous_variant 0.2
rplC 800907 c.99C>G synonymous_variant 0.16
rplC 800916 c.108A>G synonymous_variant 0.16
rplC 800937 c.129A>G synonymous_variant 0.15
rplC 800939 p.Arg44His missense_variant 0.14
rplC 800946 c.138T>C synonymous_variant 0.15
rplC 800949 c.141T>C synonymous_variant 0.15
rplC 800955 c.147C>G synonymous_variant 0.15
rplC 800967 c.159C>G synonymous_variant 0.15
rplC 800970 c.162T>C synonymous_variant 0.15
fbiC 1303632 c.702T>G synonymous_variant 0.16
fbiC 1303638 c.708A>G synonymous_variant 0.16
fbiC 1303686 c.756C>G synonymous_variant 0.21
fbiC 1303695 c.765T>C synonymous_variant 0.18
fbiC 1303708 c.778T>C synonymous_variant 0.16
fbiC 1303728 c.798G>A synonymous_variant 0.16
fbiC 1303730 p.Leu267Pro missense_variant 0.16
fbiC 1303732 p.Ser268Ala missense_variant 0.15
fbiC 1303737 c.807G>A synonymous_variant 0.15
fbiC 1303818 c.888C>G synonymous_variant 0.13
fbiC 1303911 c.981G>C synonymous_variant 0.22
fbiC 1303914 c.984C>G synonymous_variant 0.22
fbiC 1303920 c.990C>G synonymous_variant 0.21
fbiC 1303923 c.993C>T synonymous_variant 0.21
fbiC 1303929 c.999G>C synonymous_variant 0.21
fbiC 1303947 c.1017T>C synonymous_variant 0.19
fbiC 1303948 p.Gly340Arg missense_variant 0.19
fbiC 1303969 p.Val347Ile missense_variant 0.19
fbiC 1303973 p.Gly348Ala missense_variant 0.17
fbiC 1303995 c.1065C>T synonymous_variant 0.15
fbiC 1304001 c.1071C>G synonymous_variant 0.15
fbiC 1304034 c.1104A>G synonymous_variant 0.18
fbiC 1304040 c.1110C>G synonymous_variant 0.17
fbiC 1304715 c.1785G>C synonymous_variant 0.17
fbiC 1304724 c.1794A>G synonymous_variant 0.16
fbiC 1304727 c.1797A>G synonymous_variant 0.16
fbiC 1304742 c.1812T>C synonymous_variant 0.15
fbiC 1304748 c.1818T>C synonymous_variant 0.16
fbiC 1304754 c.1824G>A synonymous_variant 0.16
fbiC 1304757 c.1827A>G synonymous_variant 0.17
fbiC 1304817 c.1887T>C synonymous_variant 0.15
fbiC 1304829 c.1899T>C synonymous_variant 0.15
fbiC 1304856 c.1926C>G synonymous_variant 0.15
fbiC 1304893 p.Gly655Ser missense_variant 0.14
fbiC 1305297 c.2367G>C synonymous_variant 0.15
fbiC 1305300 c.2370A>G synonymous_variant 0.16
fbiC 1305303 c.2373T>C synonymous_variant 0.16
fbiC 1305311 p.Arg794Gln missense_variant 0.17
fbiC 1305331 p.Glu801Asn missense_variant 0.17
fbiC 1305336 c.2406T>C synonymous_variant 0.16
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.24
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.24
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.25
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.26
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.16
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.16
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.15
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.15
rrl 1473937 n.280C>T non_coding_transcript_exon_variant 0.18
rrl 1473944 n.287G>A non_coding_transcript_exon_variant 0.17
rrl 1473945 n.288T>C non_coding_transcript_exon_variant 0.17
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.16
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.15
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.15
rrl 1474104 n.447G>A non_coding_transcript_exon_variant 0.15
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.14
rrl 1474112 n.455T>A non_coding_transcript_exon_variant 0.14
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.18
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.17
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.13
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.16
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.2
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.2
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.19
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.19
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.17
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.17
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.17
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.14
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.14
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.14
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.16
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.15
rrl 1475273 n.1616T>A non_coding_transcript_exon_variant 0.14
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.14
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.16
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.16
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.14
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.15
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.21
rpsA 1833851 p.Lys104Gln missense_variant 0.95
rpsA 1834348 c.807T>C synonymous_variant 0.16
rpsA 1834498 c.957C>T synonymous_variant 0.16
rpsA 1834528 c.987T>C synonymous_variant 0.16
rpsA 1834546 c.1005T>C synonymous_variant 0.15
rpsA 1834555 c.1014T>C synonymous_variant 0.15
rpsA 1834558 c.1017C>G synonymous_variant 0.17
rpsA 1834606 c.1065C>G synonymous_variant 0.14
rpsA 1834609 c.1068T>C synonymous_variant 0.15
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.15
rpsA 1834732 c.1191T>C synonymous_variant 0.19
rpsA 1834733 p.Ala398Pro missense_variant 0.19
rpsA 1834753 c.1212T>C synonymous_variant 0.19
rpsA 1834765 c.1224A>G synonymous_variant 0.2
rpsA 1834780 c.1239A>G synonymous_variant 0.2
rpsA 1834786 c.1245A>G synonymous_variant 0.19
rpsA 1834789 c.1248T>C synonymous_variant 0.17
rpsA 1834792 c.1251G>C synonymous_variant 0.15
Rv1979c 2223241 c.-77C>G upstream_gene_variant 1.0
pncA 2289811 c.-570C>T upstream_gene_variant 1.0
pncA 2289994 c.-753A>C upstream_gene_variant 1.0
kasA 2518301 p.His63Asp missense_variant 1.0
kasA 2518672 c.558G>C synonymous_variant 0.15
kasA 2519095 c.981C>G synonymous_variant 0.15
kasA 2519104 c.990T>A synonymous_variant 0.15
kasA 2519108 p.Asp332Gln missense_variant 0.15
kasA 2519111 p.Gln333Glu missense_variant 0.14
kasA 2519125 c.1011C>T synonymous_variant 0.14
kasA 2519146 c.1032C>A synonymous_variant 0.14
kasA 2519167 c.1053T>C synonymous_variant 0.14
kasA 2519173 c.1059C>G synonymous_variant 0.14
kasA 2519176 c.1062G>A synonymous_variant 0.14
kasA 2519197 c.1083G>C synonymous_variant 0.16
pepQ 2859859 p.Ala187Glu missense_variant 1.0
Rv2752c 3064886 p.Ala436Pro missense_variant 0.97
Rv2752c 3065258 p.Met312Val missense_variant 1.0
Rv2752c 3066002 p.Met64Leu missense_variant 0.18
thyX 3067376 c.570G>C synonymous_variant 0.15
thyX 3067445 c.501C>G synonymous_variant 0.17
thyX 3067451 c.495G>A synonymous_variant 0.15
thyX 3067457 c.489C>G synonymous_variant 0.15
thyX 3067463 p.Ile161Val missense_variant 0.16
thyX 3067466 c.480G>C synonymous_variant 0.16
thyX 3067493 c.453A>G synonymous_variant 0.17
thyX 3067500 p.Lys149Arg missense_variant 0.16
thyX 3067515 p.Ser144Thr missense_variant 0.17
thyX 3067531 p.Ala139Thr missense_variant 0.12
thyX 3067619 c.327A>C synonymous_variant 0.15
thyX 3067718 c.228C>G synonymous_variant 0.17
thyX 3067721 c.225T>C synonymous_variant 0.17
thyX 3067724 c.222G>A synonymous_variant 0.18
thyX 3067727 c.219A>C synonymous_variant 0.18
thyX 3067739 c.207T>C synonymous_variant 0.18
thyX 3067742 c.204A>C synonymous_variant 0.18
thyX 3067761 p.Arg62Lys missense_variant 0.15
thyX 3067765 p.Leu61Ile missense_variant 0.15
thyX 3067781 c.165C>G synonymous_variant 0.17
thyX 3067787 c.159G>A synonymous_variant 0.18
thyX 3067793 c.153T>C synonymous_variant 0.18
thyX 3067799 c.147G>A synonymous_variant 0.17
thyX 3067802 c.144C>G synonymous_variant 0.17
thyX 3067814 c.132T>C synonymous_variant 0.17
thyX 3067826 c.120C>G synonymous_variant 0.17
thyX 3067850 c.96A>C synonymous_variant 0.15
thyA 3073925 c.547T>C synonymous_variant 0.2
thyA 3073926 c.546G>C synonymous_variant 0.19
thyA 3073929 c.543T>C synonymous_variant 0.19
thyA 3073953 c.519T>C synonymous_variant 0.16
thyA 3073977 c.495A>G synonymous_variant 0.2
thyA 3073989 c.483T>C synonymous_variant 0.19
thyA 3074001 c.471C>G synonymous_variant 0.17
thyA 3074004 c.468T>C synonymous_variant 0.18
thyA 3074010 c.462C>G synonymous_variant 0.19
thyA 3074031 c.441T>C synonymous_variant 0.17
thyA 3074037 c.435C>G synonymous_variant 0.17
thyA 3074056 p.Glu139Ala missense_variant 0.16
Rv3083 3449104 p.Pro201Ala missense_variant 1.0
Rv3236c 3612337 c.779delG frameshift_variant 1.0
fbiB 3641723 c.189T>C synonymous_variant 1.0
rpoA 3877740 c.768G>T synonymous_variant 0.87
rpoA 3877743 c.765T>C synonymous_variant 0.15
rpoA 3877839 c.669G>C synonymous_variant 0.15
rpoA 3877857 c.651G>A synonymous_variant 0.17
rpoA 3877866 c.642G>C synonymous_variant 0.16
rpoA 3877872 c.636C>T synonymous_variant 0.14
rpoA 3877986 c.522G>C synonymous_variant 0.17
rpoA 3877989 c.519A>G synonymous_variant 0.18
rpoA 3878001 c.507A>G synonymous_variant 0.17
rpoA 3878025 c.483C>T synonymous_variant 0.15
rpoA 3878028 c.480G>C synonymous_variant 0.15
rpoA 3878031 c.477T>C synonymous_variant 0.15
rpoA 3878040 c.468T>C synonymous_variant 0.17
rpoA 3878046 c.462T>C synonymous_variant 0.16
rpoA 3878049 c.459G>C synonymous_variant 0.22
rpoA 3878055 c.453A>G synonymous_variant 0.22
rpoA 3878061 c.447G>C synonymous_variant 0.24
rpoA 3878067 c.441C>G synonymous_variant 0.22
rpoA 3878070 c.438T>C synonymous_variant 0.22
rpoA 3878082 c.426T>C synonymous_variant 0.24
rpoA 3878094 c.414C>G synonymous_variant 0.24
rpoA 3878100 c.408C>G synonymous_variant 0.26
rpoA 3878103 c.405A>G synonymous_variant 0.23
rpoA 3878106 c.402G>C synonymous_variant 0.23
rpoA 3878118 c.390T>C synonymous_variant 0.23
rpoA 3878141 p.Met123Leu missense_variant 0.2
rpoA 3878142 p.Gly122Glu missense_variant 0.2
rpoA 3878169 c.339G>C synonymous_variant 0.2
rpoA 3878184 c.324C>T synonymous_variant 0.2
rpoA 3878187 c.321C>G synonymous_variant 0.19
rpoA 3878193 c.315T>C synonymous_variant 0.18
rpoA 3878202 c.306G>C synonymous_variant 0.15
rpoA 3878217 c.291A>G synonymous_variant 0.18
rpoA 3878220 c.288C>T synonymous_variant 0.16
rpoA 3878284 p.Glu75Ala missense_variant 0.14
clpC1 4038356 c.2349T>C synonymous_variant 0.14
clpC1 4038368 c.2337T>C synonymous_variant 0.16
clpC1 4038388 c.2317T>C synonymous_variant 0.14
clpC1 4038398 c.2307G>T synonymous_variant 0.15
clpC1 4038419 c.2286T>C synonymous_variant 0.16
clpC1 4038434 c.2271G>C synonymous_variant 0.16
clpC1 4038461 p.Ala748Asp missense_variant 0.14
clpC1 4038498 p.Ser736Thr missense_variant 0.17
clpC1 4038530 p.Glu725Asp missense_variant 0.21
clpC1 4038536 c.2169C>T synonymous_variant 0.19
clpC1 4038596 c.2109A>G synonymous_variant 0.23
clpC1 4038611 c.2094C>T synonymous_variant 0.2
clpC1 4038623 c.2082A>G synonymous_variant 0.2
clpC1 4038640 p.Asp689Asn missense_variant 0.21
clpC1 4038653 c.2052C>T synonymous_variant 0.14
clpC1 4038661 p.Ser682Thr missense_variant 0.14
clpC1 4038662 c.2043T>C synonymous_variant 0.15
clpC1 4038671 c.2034T>C synonymous_variant 0.16
clpC1 4038695 c.2010C>G synonymous_variant 0.14
clpC1 4038773 c.1932T>C synonymous_variant 0.16
clpC1 4038790 c.1915C>T synonymous_variant 0.16
clpC1 4038812 c.1893T>C synonymous_variant 0.15
clpC1 4038815 c.1890G>T synonymous_variant 0.18
clpC1 4038908 c.1797C>G synonymous_variant 0.16
clpC1 4038914 c.1791G>C synonymous_variant 0.15
clpC1 4038932 c.1773G>C synonymous_variant 0.16
clpC1 4038953 c.1752A>G synonymous_variant 0.15
clpC1 4038956 c.1749T>C synonymous_variant 0.14
clpC1 4038965 c.1740T>C synonymous_variant 0.15
clpC1 4038971 c.1734T>C synonymous_variant 0.14
clpC1 4038974 c.1731T>C synonymous_variant 0.14
clpC1 4038989 c.1716T>C synonymous_variant 0.15
clpC1 4039208 c.1497C>G synonymous_variant 0.17
clpC1 4039226 c.1479T>C synonymous_variant 0.15
clpC1 4039268 c.1437C>G synonymous_variant 0.16
clpC1 4039274 c.1431G>C synonymous_variant 0.16
clpC1 4039286 c.1419T>C synonymous_variant 0.17
clpC1 4039289 c.1416T>C synonymous_variant 0.16
clpC1 4039295 c.1410A>C synonymous_variant 0.16
clpC1 4039298 c.1407T>C synonymous_variant 0.16
clpC1 4039319 c.1386T>C synonymous_variant 0.19
clpC1 4039322 c.1383T>C synonymous_variant 0.19
clpC1 4039328 c.1377A>G synonymous_variant 0.17
clpC1 4039334 c.1371G>C synonymous_variant 0.16
clpC1 4039338 p.Thr456Lys missense_variant 0.14
clpC1 4039388 c.1317C>A synonymous_variant 0.13
clpC1 4039430 c.1275T>C synonymous_variant 0.17
clpC1 4039442 c.1263A>G synonymous_variant 0.17
clpC1 4039448 c.1257A>G synonymous_variant 0.17
clpC1 4039454 c.1251A>G synonymous_variant 0.18
clpC1 4039463 c.1242C>G synonymous_variant 0.18
clpC1 4039466 c.1239T>C synonymous_variant 0.18
clpC1 4039469 c.1236T>C synonymous_variant 0.19
clpC1 4039481 c.1224T>G synonymous_variant 0.23
clpC1 4039484 c.1221T>G synonymous_variant 0.22
clpC1 4039517 c.1188C>G synonymous_variant 0.19
clpC1 4039524 p.Phe394Tyr missense_variant 0.21
clpC1 4039526 c.1179G>C synonymous_variant 0.21
clpC1 4039547 c.1158C>G synonymous_variant 0.22
clpC1 4039553 c.1152C>G synonymous_variant 0.26
clpC1 4039562 c.1143C>G synonymous_variant 0.25
clpC1 4039565 c.1140G>C synonymous_variant 0.24
clpC1 4039576 p.Ala377Ser missense_variant 0.2
clpC1 4039577 c.1128T>C synonymous_variant 0.2
clpC1 4039586 c.1119G>C synonymous_variant 0.21
clpC1 4039610 c.1095G>C synonymous_variant 0.18
clpC1 4039616 c.1089G>C synonymous_variant 0.17
clpC1 4039622 c.1083C>G synonymous_variant 0.15
clpC1 4039898 c.807C>G synonymous_variant 0.17
clpC1 4039904 c.801A>G synonymous_variant 0.19
clpC1 4039928 c.775_777delAGCinsTCG synonymous_variant 0.19
clpC1 4039931 c.774T>C synonymous_variant 0.19
clpC1 4039946 c.759A>T synonymous_variant 0.22
clpC1 4039952 c.753T>C synonymous_variant 0.23
clpC1 4039958 c.747G>C synonymous_variant 0.25
clpC1 4039979 c.726C>G synonymous_variant 0.27
clpC1 4039996 p.Glu237Gln missense_variant 0.24
clpC1 4040021 c.684A>C synonymous_variant 0.27
clpC1 4040024 c.681A>G synonymous_variant 0.27
clpC1 4040033 c.672G>C synonymous_variant 0.24
clpC1 4040036 c.669C>G synonymous_variant 0.26
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.2
clpC1 4040093 c.612C>G synonymous_variant 0.21
clpC1 4040105 c.600C>G synonymous_variant 0.23
clpC1 4040363 c.342A>C synonymous_variant 0.14
clpC1 4040369 c.336C>G synonymous_variant 0.16
clpC1 4040387 c.318A>G synonymous_variant 0.14
clpC1 4040393 c.312G>C synonymous_variant 0.14
embC 4240216 c.354T>C synonymous_variant 0.15
embC 4240229 p.Leu123Met missense_variant 0.14
embC 4240233 p.Gln124Leu missense_variant 0.14
embC 4240632 p.Met257Thr missense_variant 0.15
embC 4240645 c.783G>C synonymous_variant 0.17
embC 4240654 c.792C>T synonymous_variant 0.18
embC 4240657 c.795G>C synonymous_variant 0.18
embC 4240671 p.Thr270Ile missense_variant 0.15
embC 4241005 c.1143G>T synonymous_variant 0.93
embC 4241081 c.1220delT frameshift_variant 0.88
embC 4242746 p.Pro962Ser missense_variant 1.0
embA 4243969 p.Val246Ala missense_variant 1.0
embB 4247437 c.924A>G synonymous_variant 0.15
embB 4248118 c.1605T>C synonymous_variant 0.22
embB 4248127 c.1614G>C synonymous_variant 0.2
embB 4248133 c.1620C>G synonymous_variant 0.17
embB 4248142 c.1629T>C synonymous_variant 0.16
embB 4248143 c.1630T>C synonymous_variant 0.16
embB 4248157 c.1644A>G synonymous_variant 0.16
embB 4248206 p.Ser565Gly missense_variant 0.18
embB 4248220 c.1707A>G synonymous_variant 0.19
embB 4248241 c.1728C>T synonymous_variant 0.21
embB 4249469 p.Leu986Met missense_variant 0.14
embB 4249483 c.2970C>G synonymous_variant 0.16
embB 4249486 c.2973T>G synonymous_variant 0.15
embB 4249487 c.2974T>C synonymous_variant 0.15
embB 4249521 p.Ala1003Val missense_variant 0.18
embB 4249525 c.3012T>C synonymous_variant 0.18
embB 4249528 c.3015C>G synonymous_variant 0.18
embB 4249529 p.Ile1006Val missense_variant 0.18
embB 4249532 p.Ala1007Thr missense_variant 0.17
embB 4249537 c.3024A>G synonymous_variant 0.19
embB 4249543 c.3030G>C synonymous_variant 0.19
embB 4249558 c.3045A>C synonymous_variant 0.2
embB 4249564 c.3051C>T synonymous_variant 0.2
embB 4249568 p.Ser1019Thr missense_variant 0.2
embB 4249573 c.3060T>C synonymous_variant 0.18
embB 4249580 p.Leu1023Met missense_variant 0.18
embB 4249594 c.3081G>C synonymous_variant 0.16
aftB 4269183 c.-347T>C upstream_gene_variant 0.15
ubiA 4269220 p.Ala205Lys missense_variant 0.16
aftB 4269222 c.-386T>G upstream_gene_variant 0.16
aftB 4269225 c.-389C>G upstream_gene_variant 0.16
aftB 4269231 c.-395C>G upstream_gene_variant 0.16
aftB 4269234 c.-398A>G upstream_gene_variant 0.16
ubiA 4269243 p.His197Gln missense_variant 0.15
ubiA 4269271 p.Val188Ala missense_variant 0.15