TB-Profiler result

Run: SRR6831950
Summary

Run ID: SRR6831950

Sample name:

Date: 04-04-2023 17:08:10

Number of reads: 2394279

Percentage reads mapped: 89.65

Strain: lineage4.3.3

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.3 Euro-American (LAM) mainly-LAM None 0.99
lineage4.3.3 Euro-American (LAM) LAM;T RD115 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
embB 4247448 p.His312Arg missense_variant 0.16 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6133 c.894G>C synonymous_variant 0.13
gyrB 6136 c.897G>A synonymous_variant 0.13
gyrB 6217 c.978G>C synonymous_variant 0.12
gyrB 6280 c.1041T>C synonymous_variant 0.15
gyrB 6295 c.1056A>G synonymous_variant 0.12
gyrA 7198 c.-104C>A upstream_gene_variant 0.12
gyrA 7216 c.-86G>C upstream_gene_variant 0.12
gyrA 7237 c.-65C>T upstream_gene_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7607 c.306C>G synonymous_variant 0.14
gyrA 7626 c.325C>T synonymous_variant 0.14
gyrA 7631 c.330G>C synonymous_variant 0.15
gyrA 7637 c.336C>G synonymous_variant 0.15
gyrA 7683 c.382A>C synonymous_variant 0.13
gyrA 7697 c.396C>G synonymous_variant 0.13
gyrA 7710 c.409T>C synonymous_variant 0.17
gyrA 7715 c.414G>C synonymous_variant 0.19
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.21
gyrA 7760 c.459C>T synonymous_variant 0.19
gyrA 7763 c.462T>C synonymous_variant 0.19
gyrA 7799 c.498A>G synonymous_variant 0.12
gyrA 7892 c.591G>C synonymous_variant 0.14
gyrA 7898 p.Asp199Glu missense_variant 0.15
gyrA 7919 p.Glu206Asp missense_variant 0.17
gyrA 7923 p.His208Tyr missense_variant 0.12
gyrA 8040 p.Gly247Ser missense_variant 1.0
gyrA 8069 c.768T>C synonymous_variant 0.15
gyrA 8078 c.777A>G synonymous_variant 0.16
gyrA 8090 c.789C>G synonymous_variant 0.16
gyrA 8111 c.810G>C synonymous_variant 0.16
gyrA 8225 c.924T>C synonymous_variant 0.14
gyrA 8237 c.936A>G synonymous_variant 0.14
gyrA 8253 p.Ile318Leu missense_variant 0.21
gyrA 8264 c.963T>C synonymous_variant 0.17
gyrA 8267 c.966G>C synonymous_variant 0.17
gyrA 8270 c.969G>C synonymous_variant 0.17
gyrA 8283 p.Ile328Leu missense_variant 0.14
gyrA 8288 c.987T>C synonymous_variant 0.19
gyrA 8294 c.993T>C synonymous_variant 0.19
gyrA 8324 c.1023T>C synonymous_variant 0.19
gyrA 8327 c.1026C>A synonymous_variant 0.19
gyrA 8339 c.1038A>G synonymous_variant 0.16
gyrA 8342 c.1041G>C synonymous_variant 0.15
gyrA 8366 c.1065G>C synonymous_variant 0.25
gyrA 8375 c.1074G>C synonymous_variant 0.25
gyrA 8391 p.Tyr364His missense_variant 0.3
gyrA 8399 c.1098T>C synonymous_variant 0.31
gyrA 8420 c.1119T>C synonymous_variant 0.29
gyrA 8423 c.1122G>C synonymous_variant 0.29
gyrA 8442 c.1141C>T synonymous_variant 0.34
gyrA 8453 c.1152A>C synonymous_variant 0.37
gyrA 8462 c.1161A>G synonymous_variant 0.28
gyrA 8471 c.1170T>C synonymous_variant 0.25
gyrA 8480 c.1179C>T synonymous_variant 0.19
gyrA 8486 c.1185T>C synonymous_variant 0.12
gyrA 8498 c.1197C>T synonymous_variant 0.24
gyrA 8504 c.1203G>C synonymous_variant 0.27
gyrA 8516 c.1215T>C synonymous_variant 0.28
gyrA 8519 c.1218A>C synonymous_variant 0.28
gyrA 8537 c.1236G>A synonymous_variant 0.3
gyrA 8546 c.1245T>C synonymous_variant 0.3
gyrA 8552 c.1251C>G synonymous_variant 0.29
gyrA 8556 p.Ala419Gln missense_variant 0.28
gyrA 8561 c.1260A>C synonymous_variant 0.28
gyrA 8562 c.1261C>T synonymous_variant 0.28
gyrA 8576 c.1275C>G synonymous_variant 0.28
gyrA 8597 c.1296C>G synonymous_variant 0.25
gyrA 8603 c.1302A>G synonymous_variant 0.17
gyrA 8672 c.1371A>G synonymous_variant 0.15
gyrA 8693 c.1392T>C synonymous_variant 0.13
gyrA 8699 c.1398A>G synonymous_variant 0.13
gyrA 8717 c.1416C>G synonymous_variant 0.13
gyrA 8720 c.1419G>A synonymous_variant 0.13
gyrA 8729 c.1428T>C synonymous_variant 0.14
gyrA 8732 c.1431G>C synonymous_variant 0.13
gyrA 8735 c.1434C>T synonymous_variant 0.15
gyrA 8747 c.1446A>G synonymous_variant 0.14
gyrA 8829 c.1528T>C synonymous_variant 0.14
gyrA 8939 c.1638T>C synonymous_variant 0.13
gyrA 8942 c.1641G>C synonymous_variant 0.13
gyrA 8945 c.1644G>C synonymous_variant 0.12
gyrA 8948 p.Leu549Phe missense_variant 0.14
gyrA 8951 c.1650G>A synonymous_variant 0.12
gyrA 8966 c.1665C>G synonymous_variant 0.16
gyrA 8967 p.Ala556Arg missense_variant 0.16
gyrA 8987 c.1686C>G synonymous_variant 0.16
gyrA 8990 c.1689C>G synonymous_variant 0.15
gyrA 8996 c.1695T>C synonymous_variant 0.16
gyrA 8998 p.Leu566Trp missense_variant 0.18
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491191 p.Gly137Arg missense_variant 0.14
fgd1 491196 c.414A>G synonymous_variant 0.15
fgd1 491202 c.420G>C synonymous_variant 0.15
fgd1 491203 p.Gln141Glu missense_variant 0.15
fgd1 491212 p.Ser144Arg missense_variant 0.13
fgd1 491217 c.435T>C synonymous_variant 0.14
fgd1 491532 c.750G>T synonymous_variant 0.12
fgd1 491542 c.760T>C synonymous_variant 0.14
fgd1 491547 c.765A>C synonymous_variant 0.13
fgd1 491550 c.768T>C synonymous_variant 0.12
ccsA 620703 c.813G>C synonymous_variant 0.12
ccsA 620710 p.Val274Met missense_variant 0.12
ccsA 620721 c.831G>C synonymous_variant 0.12
ccsA 620730 c.840C>T synonymous_variant 0.12
ccsA 620733 c.843G>C synonymous_variant 0.12
ccsA 620734 c.844C>A synonymous_variant 0.12
ccsA 620739 c.849A>G synonymous_variant 0.12
ccsA 620748 c.858T>A synonymous_variant 0.12
rpoB 760181 c.375T>C synonymous_variant 0.12
rpoB 760196 c.390C>G synonymous_variant 0.13
rpoB 760283 c.477G>C synonymous_variant 0.15
rpoB 760328 c.522G>C synonymous_variant 0.14
rpoB 760331 c.525G>C synonymous_variant 0.13
rpoB 760340 c.534G>C synonymous_variant 0.14
rpoB 760406 c.600G>C synonymous_variant 0.12
rpoB 760418 c.612G>C synonymous_variant 0.12
rpoB 760424 c.618C>G synonymous_variant 0.12
rpoB 760430 c.624T>C synonymous_variant 0.16
rpoB 760475 c.669A>G synonymous_variant 0.16
rpoB 760481 c.675G>C synonymous_variant 0.17
rpoB 760484 c.678A>G synonymous_variant 0.16
rpoB 760886 c.1080A>G synonymous_variant 0.21
rpoB 760919 c.1113C>G synonymous_variant 0.2
rpoB 760925 c.1119T>C synonymous_variant 0.21
rpoB 760928 c.1122G>C synonymous_variant 0.21
rpoB 760934 c.1128C>T synonymous_variant 0.19
rpoB 760946 c.1140A>G synonymous_variant 0.19
rpoB 760970 c.1164G>C synonymous_variant 0.16
rpoB 761150 c.1344A>C synonymous_variant 0.17
rpoB 761165 c.1359G>C synonymous_variant 0.17
rpoB 761168 c.1362C>G synonymous_variant 0.18
rpoB 761171 c.1365C>T synonymous_variant 0.17
rpoB 761180 c.1374A>C synonymous_variant 0.15
rpoB 761183 c.1377T>G synonymous_variant 0.16
rpoB 761189 c.1383T>G synonymous_variant 0.19
rpoB 761222 c.1416G>C synonymous_variant 0.18
rpoB 761249 c.1443A>G synonymous_variant 0.15
rpoB 761255 c.1449T>G synonymous_variant 0.14
rpoB 761261 c.1455G>T synonymous_variant 0.16
rpoB 761327 c.1521A>G synonymous_variant 0.18
rpoB 761360 c.1554T>C synonymous_variant 0.13
rpoB 762148 c.2343G>C synonymous_variant 0.12
rpoC 763028 c.-342T>C upstream_gene_variant 0.23
rpoC 763031 c.-339T>G upstream_gene_variant 0.23
rpoC 763034 c.-336C>G upstream_gene_variant 0.23
rpoC 763040 c.-330C>G upstream_gene_variant 0.26
rpoC 763070 c.-300T>C upstream_gene_variant 0.27
rpoC 763076 c.-294C>G upstream_gene_variant 0.27
rpoC 763085 c.-285C>G upstream_gene_variant 0.32
rpoC 763115 c.-255T>C upstream_gene_variant 0.25
rpoC 763148 c.-222G>C upstream_gene_variant 0.19
rpoC 763158 c.-212C>T upstream_gene_variant 0.16
rpoC 763166 c.-204A>G upstream_gene_variant 0.12
rpoC 763169 c.-201A>G upstream_gene_variant 0.13
rpoC 763402 c.33C>G synonymous_variant 0.25
rpoC 763411 c.42T>G synonymous_variant 0.27
rpoC 763414 c.45T>C synonymous_variant 0.27
rpoC 763441 c.72C>G synonymous_variant 0.32
rpoC 763444 c.75T>C synonymous_variant 0.32
rpoC 763456 c.87A>G synonymous_variant 0.29
rpoC 763468 c.99G>C synonymous_variant 0.29
rpoC 763546 c.177A>G synonymous_variant 0.15
rpoC 763570 c.201G>C synonymous_variant 0.17
rpoC 763594 c.225C>T synonymous_variant 0.17
rpoC 763696 c.327T>C synonymous_variant 0.23
rpoC 763702 c.333C>G synonymous_variant 0.23
rpoC 763708 c.339G>A synonymous_variant 0.23
rpoC 763709 c.340C>T synonymous_variant 0.23
rpoC 763714 c.345G>C synonymous_variant 0.25
rpoC 763717 c.348T>C synonymous_variant 0.26
rpoC 763723 c.354G>C synonymous_variant 0.3
rpoC 763732 c.363C>G synonymous_variant 0.37
rpoC 763735 c.366G>C synonymous_variant 0.35
rpoC 763744 c.375G>C synonymous_variant 0.35
rpoC 763765 c.396T>C synonymous_variant 0.37
rpoC 763768 c.399C>G synonymous_variant 0.35
rpoC 763780 c.411C>G synonymous_variant 0.31
rpoC 763783 c.414G>C synonymous_variant 0.29
rpoC 763801 c.432C>G synonymous_variant 0.25
rpoC 763807 c.438T>C synonymous_variant 0.24
rpoC 763819 c.450G>C synonymous_variant 0.23
rpoC 763831 c.462A>G synonymous_variant 0.14
rpoC 763836 p.Ala156Val missense_variant 0.12
rpoC 763858 c.489A>G synonymous_variant 0.14
rpoC 763872 p.Gly168Ala missense_variant 0.12
rpoC 763876 p.Glu169Asp missense_variant 0.12
rpoC 763879 c.510A>G synonymous_variant 0.12
rpoC 763891 c.522G>C synonymous_variant 0.12
rpoC 764005 c.636G>C synonymous_variant 0.12
rpoC 764011 c.642T>C synonymous_variant 0.12
rpoC 764024 c.655T>C synonymous_variant 0.15
rpoC 764044 c.675T>C synonymous_variant 0.18
rpoC 764059 c.690G>C synonymous_variant 0.17
rpoC 764083 c.714A>G synonymous_variant 0.21
rpoC 764098 c.729A>G synonymous_variant 0.25
rpoC 764101 c.732C>G synonymous_variant 0.24
rpoC 764131 c.762T>C synonymous_variant 0.25
rpoC 764161 c.792G>C synonymous_variant 0.19
rpoC 764188 c.819A>G synonymous_variant 0.18
rpoC 764195 p.Ser276Gln missense_variant 0.16
rpoC 764203 c.834G>T synonymous_variant 0.16
rpoC 764206 c.837T>C synonymous_variant 0.15
rpoC 764257 c.888G>C synonymous_variant 0.38
rpoC 764266 c.897T>C synonymous_variant 0.32
rpoC 764269 c.900G>C synonymous_variant 0.32
rpoC 764278 c.909A>G synonymous_variant 0.29
rpoC 764282 c.913_915delTCGinsAGC synonymous_variant 0.28
rpoC 764320 c.951C>G synonymous_variant 0.17
rpoC 764431 c.1062G>C synonymous_variant 0.12
rpoC 764446 c.1077T>C synonymous_variant 0.13
rpoC 764893 c.1524T>C synonymous_variant 0.17
rpoC 764911 c.1542A>G synonymous_variant 0.18
rpoC 764923 c.1554A>G synonymous_variant 0.19
rpoC 764932 c.1563C>A synonymous_variant 0.21
rpoC 764968 c.1599T>C synonymous_variant 0.22
rpoC 764995 c.1626C>G synonymous_variant 0.93
rpoC 765007 c.1638T>G synonymous_variant 0.13
rpoC 765073 c.1704G>C synonymous_variant 0.15
rpoC 765076 c.1707A>G synonymous_variant 0.15
rpoC 765079 c.1710T>G synonymous_variant 0.15
rpoC 765082 c.1713G>C synonymous_variant 0.14
rpoC 765085 c.1716T>G synonymous_variant 0.14
rpoC 765089 c.1720T>C synonymous_variant 0.14
rpoC 765103 c.1734G>A synonymous_variant 0.14
rpoC 765287 c.1918C>T synonymous_variant 0.15
rpoC 765292 c.1923G>T synonymous_variant 0.12
rpoC 765478 c.2109T>C synonymous_variant 0.2
rpoC 765499 c.2130C>G synonymous_variant 0.18
rpoC 765508 c.2139C>G synonymous_variant 0.17
rpoC 765613 p.His748Gln missense_variant 0.16
rpoC 765625 c.2256C>G synonymous_variant 0.18
rpoC 765628 c.2259G>C synonymous_variant 0.18
rpoC 765631 p.Asp754Glu missense_variant 0.18
rpoC 765658 c.2289C>T synonymous_variant 0.19
rpoC 765928 c.2559C>G synonymous_variant 0.17
rpoC 765967 c.2598C>T synonymous_variant 0.2
rpoC 765979 c.2610C>G synonymous_variant 0.19
rpoC 765982 c.2613C>T synonymous_variant 0.17
rpoC 765985 c.2616C>T synonymous_variant 0.19
rpoC 765994 c.2625A>T synonymous_variant 0.18
rpoC 766043 p.Gln892Glu missense_variant 0.12
rpoC 766069 c.2700G>A synonymous_variant 0.14
rpoC 766444 c.3075C>G synonymous_variant 0.14
rpoC 766447 c.3078T>C synonymous_variant 0.14
rpoC 766726 c.3357T>C synonymous_variant 0.13
rpoC 766738 c.3369G>T synonymous_variant 0.15
rpoC 766750 c.3381C>G synonymous_variant 0.14
rpoC 766765 c.3396A>C synonymous_variant 0.12
rpoC 766774 c.3405T>C synonymous_variant 0.17
rpoC 766918 c.3549C>T synonymous_variant 0.13
rpoC 766963 c.3594T>C synonymous_variant 0.14
rpoC 766972 c.3603G>C synonymous_variant 0.14
rpoC 766996 c.3627C>T synonymous_variant 0.17
rpoC 767009 c.3640_3642delTCGinsAGC synonymous_variant 0.17
rpoC 767014 c.3645G>C synonymous_variant 0.17
rpoC 767033 c.3664_3666delTCGinsAGT synonymous_variant 0.15
rpoC 767062 c.3693C>A synonymous_variant 0.12
rpoC 767074 c.3705T>C synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781760 c.201T>C synonymous_variant 0.14
rpsL 781793 c.234G>C synonymous_variant 0.14
rpsL 781832 c.273T>C synonymous_variant 0.17
rpsL 781841 c.282C>G synonymous_variant 0.2
rpsL 781859 c.300T>C synonymous_variant 0.15
rpsL 781868 c.309T>C synonymous_variant 0.16
rpsL 781871 c.312G>C synonymous_variant 0.12
rpsL 781892 c.333A>G synonymous_variant 0.17
rpsL 781898 c.339A>T synonymous_variant 0.2
rpsL 781916 c.357T>C synonymous_variant 0.21
rpsL 781929 p.Gly124Ser missense_variant 0.13
rplC 800747 c.-62C>G upstream_gene_variant 0.17
rplC 800771 c.-38C>T upstream_gene_variant 0.26
rplC 800814 c.6A>G synonymous_variant 0.2
rplC 800817 c.9A>T synonymous_variant 0.2
rplC 800844 c.36T>C synonymous_variant 0.15
fbiC 1303095 c.165G>A synonymous_variant 0.96
fbiC 1303534 p.Ser202Ala missense_variant 0.12
fbiC 1303914 c.984C>G synonymous_variant 0.12
fbiC 1303929 c.999G>C synonymous_variant 0.14
fbiC 1303947 c.1017T>C synonymous_variant 0.13
fbiC 1303948 p.Gly340Arg missense_variant 0.13
fbiC 1303969 p.Val347Ile missense_variant 0.17
fbiC 1303973 p.Gly348Ala missense_variant 0.17
fbiC 1303981 p.Val351Ile missense_variant 0.17
fbiC 1303995 c.1065C>T synonymous_variant 0.19
atpE 1461152 c.108C>T synonymous_variant 0.16
atpE 1461159 p.Val39Ile missense_variant 0.16
atpE 1461185 c.141G>C synonymous_variant 0.22
atpE 1461189 c.145C>T synonymous_variant 0.21
atpE 1461194 c.150C>T synonymous_variant 0.18
atpE 1461197 c.153A>G synonymous_variant 0.16
atpE 1461219 c.175T>C synonymous_variant 0.16
atpE 1461224 c.180T>C synonymous_variant 0.17
atpE 1461233 c.189A>G synonymous_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.18
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.16
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.16
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.16
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.15
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.15
rrs 1472031 n.186G>A non_coding_transcript_exon_variant 0.15
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.17
rrs 1472044 n.199G>C non_coding_transcript_exon_variant 0.22
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.17
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.15
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.13
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.13
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.13
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.28
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.28
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.18
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.18
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.18
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.18
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.31
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.35
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.25
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.21
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.16
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.16
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.15
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.14
rrl 1474823 n.1166C>T non_coding_transcript_exon_variant 0.15
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.15
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.12
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.15
rrl 1474959 n.1302C>T non_coding_transcript_exon_variant 0.16
rrl 1474962 n.1306delG non_coding_transcript_exon_variant 0.16
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.24
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 0.18
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.16
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.14
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.18
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.24
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.2
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.18
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.19
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.2
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.23
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.17
rrl 1475271 n.1614A>C non_coding_transcript_exon_variant 0.14
rrl 1475273 n.1616T>A non_coding_transcript_exon_variant 0.14
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.14
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.14
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.14
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.13
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.13
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.18
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.21
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.16
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.16
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.13
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.21
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.19
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.2
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.19
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.14
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.14
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.14
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.14
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.15
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.17
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.21
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.22
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.24
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.22
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.2
inhA 1673574 c.-628C>G upstream_gene_variant 0.13
inhA 1674285 c.84A>G synonymous_variant 0.12
inhA 1674295 p.Gln32Ala missense_variant 0.17
inhA 1674300 c.99C>G synonymous_variant 0.18
inhA 1674303 c.102C>G synonymous_variant 0.17
inhA 1674307 c.106C>T synonymous_variant 0.17
inhA 1674315 c.114C>G synonymous_variant 0.26
inhA 1674321 c.120G>C synonymous_variant 0.3
inhA 1674342 c.141T>C synonymous_variant 0.21
inhA 1674352 p.Thr51Val missense_variant 0.18
inhA 1674368 p.Ala56Glu missense_variant 0.13
inhA 1674379 c.178C>T synonymous_variant 0.14
inhA 1674486 c.285T>C synonymous_variant 0.12
inhA 1674507 c.306G>C synonymous_variant 0.16
inhA 1674537 c.336C>G synonymous_variant 0.21
inhA 1674542 p.Ala114Glu missense_variant 0.22
inhA 1674549 c.348G>C synonymous_variant 0.15
inhA 1674555 c.354G>A synonymous_variant 0.13
inhA 1674582 c.381T>C synonymous_variant 0.17
inhA 1674585 c.384T>C synonymous_variant 0.21
inhA 1674589 p.Met130Leu missense_variant 0.19
inhA 1674624 c.423A>C synonymous_variant 0.18
inhA 1674627 c.426T>G synonymous_variant 0.21
inhA 1674630 c.429C>G synonymous_variant 0.21
inhA 1674636 c.435C>G synonymous_variant 0.19
inhA 1674639 c.438C>T synonymous_variant 0.18
inhA 1674654 c.453G>C synonymous_variant 0.18
rpsA 1833787 c.246C>G synonymous_variant 0.12
rpsA 1833790 c.249T>A synonymous_variant 0.12
rpsA 1833799 c.258C>G synonymous_variant 0.14
rpsA 1833811 c.270G>C synonymous_variant 0.14
rpsA 1834474 c.933C>G synonymous_variant 0.12
rpsA 1834836 p.Met432Thr missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102050 c.993T>C synonymous_variant 0.12
ndh 2102053 c.990G>C synonymous_variant 0.13
ndh 2102059 c.984T>C synonymous_variant 0.16
ndh 2102065 c.978G>C synonymous_variant 0.16
ndh 2102068 c.975T>C synonymous_variant 0.14
ndh 2102076 p.Met323Leu missense_variant 0.14
ndh 2102077 c.966T>C synonymous_variant 0.15
ndh 2102083 p.Val320Ile missense_variant 0.14
ndh 2102218 c.825C>G synonymous_variant 0.12
ndh 2102233 c.810G>A synonymous_variant 0.13
ndh 2102242 c.801G>A synonymous_variant 0.19
katG 2156196 c.-85C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518468 c.354A>T synonymous_variant 0.15
kasA 2518475 c.361A>C synonymous_variant 0.15
kasA 2518480 c.366T>C synonymous_variant 0.15
kasA 2518483 c.369C>G synonymous_variant 0.14
kasA 2518504 c.390T>C synonymous_variant 0.16
kasA 2518506 p.Ala131Glu missense_variant 0.15
kasA 2518519 c.405G>C synonymous_variant 0.24
kasA 2518528 c.414C>G synonymous_variant 0.22
kasA 2518540 c.426T>G synonymous_variant 0.21
kasA 2518561 c.447T>C synonymous_variant 0.21
kasA 2518567 c.453G>C synonymous_variant 0.12
kasA 2518570 c.456G>C synonymous_variant 0.12
kasA 2518588 c.474T>C synonymous_variant 0.13
kasA 2518591 c.477G>C synonymous_variant 0.13
kasA 2518696 c.582C>G synonymous_variant 0.12
kasA 2518702 c.588C>T synonymous_variant 0.12
kasA 2518714 c.600A>C synonymous_variant 0.13
kasA 2518717 c.603C>T synonymous_variant 0.14
kasA 2518732 c.618C>G synonymous_variant 0.18
kasA 2518741 c.627G>C synonymous_variant 0.17
kasA 2518747 c.633C>G synonymous_variant 0.17
kasA 2518768 c.654C>G synonymous_variant 0.16
kasA 2518919 p.Gly269Ser missense_variant 0.94
kasA 2519008 c.894C>T synonymous_variant 0.13
ahpC 2726638 p.Ala149Val missense_variant 0.12
ahpC 2726657 c.465A>C synonymous_variant 0.12
ahpC 2726681 c.489A>G synonymous_variant 0.13
ahpC 2726687 c.495C>G synonymous_variant 0.13
ahpC 2726690 c.498C>T synonymous_variant 0.12
folC 2746340 p.Ala420Val missense_variant 1.0
folC 2746594 c.1005T>C synonymous_variant 0.12
folC 2746597 c.1002C>A synonymous_variant 0.12
Rv2752c 3066118 p.Asn25Ser missense_variant 0.14
thyX 3067694 c.252G>C synonymous_variant 0.16
thyA 3073824 c.648A>C synonymous_variant 0.12
thyA 3073839 c.633T>C synonymous_variant 0.14
thyA 3073863 c.609T>C synonymous_variant 0.19
thyA 3073868 p.Thr202Ala missense_variant 0.8
thyA 3073872 p.Ile200Val missense_variant 0.2
thyA 3073878 c.594G>A synonymous_variant 0.22
thyA 3073902 c.570C>G synonymous_variant 0.15
thyA 3073953 c.519T>C synonymous_variant 0.16
thyA 3073989 c.483T>C synonymous_variant 0.17
thyA 3074001 c.471C>G synonymous_variant 0.19
thyA 3074004 c.468T>C synonymous_variant 0.19
thyA 3074010 c.462C>G synonymous_variant 0.19
thyA 3074172 c.300G>C synonymous_variant 0.15
thyA 3074175 c.297A>G synonymous_variant 0.13
thyA 3074199 c.273G>A synonymous_variant 0.16
thyA 3074205 p.Glu89Asp missense_variant 0.17
thyA 3074214 c.258T>C synonymous_variant 0.17
thyA 3074217 c.255T>C synonymous_variant 0.21
thyA 3074349 c.123T>C synonymous_variant 0.12
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3475036 p.Val344Thr missense_variant 0.16
fprA 3475047 c.1041A>G synonymous_variant 0.15
fprA 3475048 p.Ile348Val missense_variant 0.14
fprA 3475051 p.Asn349Glu missense_variant 0.14
rpoA 3877638 c.870T>C synonymous_variant 0.13
rpoA 3877656 c.852T>C synonymous_variant 0.12
rpoA 3877692 c.816G>C synonymous_variant 0.14
rpoA 3877704 c.804G>T synonymous_variant 0.12
rpoA 3877857 c.651G>A synonymous_variant 0.16
rpoA 3877866 c.642G>C synonymous_variant 0.16
rpoA 3877872 c.636C>T synonymous_variant 0.16
rpoA 3877875 c.633T>G synonymous_variant 0.16
rpoA 3877908 c.600T>C synonymous_variant 0.14
rpoA 3877989 c.519A>G synonymous_variant 0.14
rpoA 3878001 c.507A>G synonymous_variant 0.12
rpoA 3878049 c.459G>C synonymous_variant 0.12
rpoA 3878055 c.453A>G synonymous_variant 0.15
rpoA 3878061 c.447G>C synonymous_variant 0.15
rpoA 3878070 c.438T>C synonymous_variant 0.12
rpoA 3878082 c.426T>C synonymous_variant 0.16
rpoA 3878094 c.414C>G synonymous_variant 0.17
rpoA 3878100 c.408C>G synonymous_variant 0.18
rpoA 3878103 c.405A>G synonymous_variant 0.14
rpoA 3878106 c.402G>C synonymous_variant 0.14
rpoA 3878118 c.390T>C synonymous_variant 0.15
rpoA 3878141 p.Met123Leu missense_variant 0.2
rpoA 3878142 p.Gly122Glu missense_variant 0.21
rpoA 3878169 c.339G>C synonymous_variant 0.21
rpoA 3878184 c.324C>T synonymous_variant 0.18
rpoA 3878187 c.321C>G synonymous_variant 0.18
rpoA 3878193 c.315T>C synonymous_variant 0.18
rpoA 3878199 c.309T>C synonymous_variant 0.16
rpoA 3878202 c.306G>C synonymous_variant 0.16
rpoA 3878217 c.291A>G synonymous_variant 0.14
rpoA 3878220 c.288C>T synonymous_variant 0.13
rpoA 3878271 c.237T>C synonymous_variant 0.15
rpoA 3878284 p.Glu75Ala missense_variant 0.15
rpoA 3878292 c.216T>C synonymous_variant 0.13
rpoA 3878304 c.204G>C synonymous_variant 0.16
rpoA 3878313 c.195G>C synonymous_variant 0.15
rpoA 3878322 c.186A>G synonymous_variant 0.17
rpoA 3878337 c.171T>C synonymous_variant 0.13
rpoA 3878346 c.162T>C synonymous_variant 0.17
rpoA 3878376 c.132G>C synonymous_variant 0.14
rpoA 3878385 c.123C>G synonymous_variant 0.13
rpoA 3878396 c.112C>T synonymous_variant 0.14
clpC1 4038212 c.2493T>C synonymous_variant 0.14
clpC1 4038271 p.Pro812Ala missense_variant 0.17
clpC1 4038272 p.Gly811Ser missense_variant 0.17
clpC1 4038278 c.2427T>C synonymous_variant 0.18
clpC1 4038287 c.2418C>T synonymous_variant 0.87
clpC1 4038293 c.2412G>C synonymous_variant 0.17
clpC1 4038302 c.2403C>G synonymous_variant 0.16
clpC1 4038498 p.Ser736Thr missense_variant 0.17
clpC1 4038740 c.1965G>C synonymous_variant 0.13
clpC1 4038755 c.1950G>C synonymous_variant 0.17
clpC1 4038773 c.1932T>C synonymous_variant 0.17
clpC1 4038782 c.1923G>C synonymous_variant 0.23
clpC1 4038790 c.1915C>T synonymous_variant 0.2
clpC1 4038812 c.1893T>C synonymous_variant 0.22
clpC1 4038815 c.1890G>T synonymous_variant 0.22
clpC1 4038908 c.1797C>G synonymous_variant 0.16
clpC1 4038914 c.1791G>C synonymous_variant 0.13
clpC1 4038968 c.1737G>A synonymous_variant 0.92
clpC1 4039448 c.1257A>G synonymous_variant 0.13
clpC1 4039454 c.1251A>G synonymous_variant 0.14
clpC1 4039553 c.1152C>G synonymous_variant 0.13
clpC1 4039562 c.1143C>G synonymous_variant 0.17
clpC1 4039576 p.Ala377Ser missense_variant 0.16
clpC1 4039577 c.1128T>C synonymous_variant 0.16
clpC1 4039586 c.1119G>C synonymous_variant 0.18
clpC1 4039610 c.1095G>C synonymous_variant 0.17
clpC1 4039616 c.1089G>C synonymous_variant 0.17
clpC1 4039622 c.1083C>G synonymous_variant 0.16
clpC1 4039817 c.888A>T synonymous_variant 0.13
clpC1 4039820 c.885T>G synonymous_variant 0.13
clpC1 4039831 c.874T>C synonymous_variant 0.15
clpC1 4039832 c.873C>G synonymous_variant 0.14
clpC1 4039850 c.855T>C synonymous_variant 0.14
clpC1 4039865 c.840T>C synonymous_variant 0.12
clpC1 4040354 c.351A>G synonymous_variant 0.21
clpC1 4040363 c.342A>C synonymous_variant 0.17
clpC1 4040369 c.336C>G synonymous_variant 0.15
clpC1 4040480 c.225T>C synonymous_variant 0.12
panD 4044478 c.-197G>A upstream_gene_variant 0.12
embC 4240979 p.Thr373Gln missense_variant 0.14
embC 4240983 p.Ser374Asn missense_variant 0.13
embC 4240990 c.1128A>G synonymous_variant 0.13
embC 4240996 c.1134G>C synonymous_variant 0.14
embC 4241017 c.1155T>C synonymous_variant 0.17
embC 4241023 c.1161T>G synonymous_variant 0.15
embC 4241026 c.1164C>G synonymous_variant 0.15
embC 4241035 c.1173G>A synonymous_variant 0.13
embC 4241050 c.1188T>G synonymous_variant 0.17
embC 4241086 c.1224G>C synonymous_variant 0.22
embC 4241104 c.1242G>A synonymous_variant 0.24
embC 4241107 c.1245G>C synonymous_variant 0.21
embC 4241137 c.1275G>C synonymous_variant 0.19
embC 4241140 c.1278A>G synonymous_variant 0.16
embC 4241141 p.Ile427Val missense_variant 0.16
embC 4241158 c.1296T>C synonymous_variant 0.13
embC 4241161 c.1299C>G synonymous_variant 0.13
embC 4241509 c.1647A>G synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4245149 c.1917C>G synonymous_variant 0.13
embA 4245182 c.1950T>C synonymous_variant 0.12
embB 4247437 c.924A>G synonymous_variant 0.16
embB 4247440 c.927C>G synonymous_variant 0.17
embB 4247464 c.951C>G synonymous_variant 0.16
embB 4247470 c.957T>C synonymous_variant 0.17
embB 4247491 c.978G>C synonymous_variant 0.16
embB 4247497 c.984T>C synonymous_variant 0.15
embB 4247500 c.987C>G synonymous_variant 0.15
embB 4247512 c.999T>C synonymous_variant 0.15
embB 4247536 c.1023C>G synonymous_variant 0.15
embB 4247554 c.1041T>C synonymous_variant 0.14
embB 4247566 c.1053C>G synonymous_variant 0.14
embB 4247567 c.1054C>T synonymous_variant 0.15
embB 4247572 c.1059A>G synonymous_variant 0.14
embB 4247579 p.Ala356Phe missense_variant 0.15
embB 4248035 p.Val508Ile missense_variant 0.14
embB 4248041 p.Ala510Thr missense_variant 0.15
embB 4248044 p.Lys511Ala missense_variant 0.16
embB 4248052 c.1539G>A synonymous_variant 0.15
embB 4248055 c.1542G>C synonymous_variant 0.14
embB 4248064 c.1551G>C synonymous_variant 0.17
embB 4248070 c.1557T>C synonymous_variant 0.16
embB 4248085 c.1572T>C synonymous_variant 0.16
embB 4248097 c.1584C>G synonymous_variant 0.14
embB 4248127 c.1614G>C synonymous_variant 0.13
embB 4248133 c.1620C>G synonymous_variant 0.16
embB 4248142 c.1629T>C synonymous_variant 0.16
embB 4248143 c.1630T>C synonymous_variant 0.15
embB 4248157 c.1644A>G synonymous_variant 0.13
embB 4248206 p.Ser565Gly missense_variant 0.13
embB 4248220 c.1707A>G synonymous_variant 0.16
embB 4249469 p.Leu986Met missense_variant 0.13
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408156 p.Leu16Arg missense_variant 1.0