Run ID: 7eccd9e7-f25a-4f55-98c7-9afb76970df1
Sample name:
Date: 31-10-2023 04:55:17
Number of reads: 710162
Percentage reads mapped: 92.96
Median coverage: 0
Strain:
Spoligotype:
Drug-resistance: Sensitive
| Lineage | Family | RDs | Frequency |
|---|
| Drug | Resistance | Supporting mutations | WHO confidence | Comment |
|---|---|---|---|---|
| rifampicin | ||||
| isoniazid | ||||
| ethambutol | ||||
| pyrazinamide | ||||
| moxifloxacin | ||||
| levofloxacin | ||||
| bedaquiline | ||||
| delamanid | ||||
| pretomanid | ||||
| linezolid | ||||
| streptomycin | ||||
| amikacin | ||||
| kanamycin | ||||
| capreomycin | ||||
| clofazimine | ||||
| ethionamide | ||||
| para-aminosalicylic_acid | ||||
| cycloserine |
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
|---|
| Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
|---|---|---|---|---|---|---|
| gyrA | 6622 | c.-680C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6634 | c.-668T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6637 | c.-665T>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6640 | c.-662A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6643 | c.-659A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6649 | c.-653T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6655 | c.-647T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6670 | c.-632G>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6673 | c.-629A>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6676 | c.-626T>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6680 | c.-622C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6700 | c.-602T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6703 | c.-599G>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6709 | c.-593A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6712 | c.-590G>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6728 | c.-574_-572delCTAinsTTG | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6745 | c.-557T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6760 | c.-542G>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6769 | c.-533C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6775 | c.-527G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6787 | c.-515G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6820 | c.-482C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6838 | c.-464C>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6841 | c.-461T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6844 | c.-458T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6853 | c.-449A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6856 | c.-446T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6859 | c.-443T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6862 | c.-440C>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6866 | c.-436C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6889 | c.-413G>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6898 | c.-404G>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6904 | c.-398C>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6919 | c.-383T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6925 | c.-377T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6931 | c.-371A>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6934 | c.-368A>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6941 | c.-361C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6952 | c.-350C>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6955 | c.-347G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6982 | c.-320A>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 6991 | c.-311C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7000 | c.-302C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7006 | c.-296T>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7007 | c.-295C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7018 | c.-284G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7081 | c.-221T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7090 | c.-212C>T | upstream_gene_variant | 0.9 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7093 | c.-209T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7099 | c.-203G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7108 | c.-194G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7120 | c.-182T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7123 | c.-179C>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7129 | c.-173T>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7132 | c.-170T>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7135 | c.-167G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7136 | c.-166T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7147 | c.-155G>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7151 | c.-151C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7165 | c.-137C>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrB | 7172 | p.Asp645Asn | missense_variant | 0.14 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7178 | c.-124T>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7198 | c.-104C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7207 | c.-95C>G | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7210 | c.-92C>T | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7213 | c.-89G>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7216 | c.-86G>C | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7219 | c.-83C>A | upstream_gene_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7391 | c.90C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7394 | c.93T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7406 | c.105G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7421 | c.120G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7430 | c.129G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7442 | c.141G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7451 | c.150C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7457 | c.156T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7460 | c.159C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7463 | c.162G>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7469 | c.168C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7472 | c.171T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7475 | c.174A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7480 | p.Phe60Tyr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7484 | c.183T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7487 | c.186C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7490 | c.189C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7496 | c.195C>T | synonymous_variant | 0.99 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7502 | c.201C>T | synonymous_variant | 0.99 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7523 | c.222C>A | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7532 | c.231T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7541 | c.240C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7556 | c.255C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | Uncertain significance | |||||
| levofloxacin | Uncertain significance | |||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7595 | c.294C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7601 | c.300C>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7619 | c.318C>T | synonymous_variant | 0.99 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7622 | c.321C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7631 | c.330G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7637 | c.336C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7652 | c.351C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7658 | c.357A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7664 | c.363T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7667 | c.366C>T | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7683 | c.382_384delAGGinsCGC | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7694 | c.393A>G | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7710 | c.409T>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7715 | c.414G>C | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| gyrA | 7728 | c.427_429delAGGinsCGT | synonymous_variant | 1.0 | fluoroquinolones | |
| moxifloxacin | ||||||
| levofloxacin | ||||||
| ciprofloxacin | ||||||
| ofloxacin | ||||||
| rrs | 1472119 | n.274G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472307 | n.462C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | ||||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472969 | n.1124A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472970 | n.1125C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472977 | n.1132G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrs | 1472978 | n.1133T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| kanamycin | ||||||
| capreomycin | ||||||
| amikacin | Uncertain significance | |||||
| aminoglycosides | ||||||
| streptomycin | ||||||
| rrl | 1473403 | n.-255C>T | upstream_gene_variant | 0.99 | linezolid | |
| rrl | 1473417 | n.-241C>T | upstream_gene_variant | 1.0 | linezolid | |
| rrl | 1473419 | n.-239T>C | upstream_gene_variant | 0.99 | linezolid | |
| rrl | 1473421 | n.-237G>A | upstream_gene_variant | 0.97 | linezolid | |
| rrl | 1475988 | n.2331A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476035 | n.2378G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476086 | n.2429G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476089 | n.2432T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476095 | n.2438C>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476115 | n.2458T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476117 | n.2460G>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476214 | n.2557G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476251 | n.2594T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476297 | n.2640C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476299 | n.2642C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | Uncertain significance |
| rrl | 1476529 | n.2872A>G | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476580 | n.2923G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| rrl | 1476619 | n.2962C>T | non_coding_transcript_exon_variant | 1.0 | linezolid | |
| inhA | 1674443 | p.Ala81Val | missense_variant | 0.5 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674450 | c.249G>T | synonymous_variant | 0.42 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674453 | c.252G>C | synonymous_variant | 0.42 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674471 | c.270G>C | synonymous_variant | 0.78 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674477 | c.276G>C | synonymous_variant | 0.78 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674480 | c.279T>C | synonymous_variant | 0.78 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674486 | c.285T>C | synonymous_variant | 0.79 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674489 | c.288G>C | synonymous_variant | 0.78 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674501 | c.300G>A | synonymous_variant | 0.78 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674503 | p.Thr101Ser | missense_variant | 0.79 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674513 | c.312C>T | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674542 | p.Ala114Glu | missense_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674546 | c.345T>C | synonymous_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674558 | c.357C>T | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674570 | c.369G>C | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674576 | c.375T>C | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674579 | c.378G>C | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674582 | c.381T>C | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674594 | c.393C>A | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674609 | c.408G>C | synonymous_variant | 0.93 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674618 | c.417C>T | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674620 | p.Pro140Arg | missense_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674624 | c.423A>T | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674627 | c.426T>C | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674702 | c.501G>A | synonymous_variant | 0.85 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674703 | c.502T>C | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674718 | c.517_519delAGGinsCGC | synonymous_variant | 0.87 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674729 | c.528G>C | synonymous_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674741 | c.540C>T | synonymous_variant | 0.91 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674756 | c.555T>C | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674762 | c.561T>C | synonymous_variant | 0.88 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674774 | c.573A>C | synonymous_variant | 0.87 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674777 | c.576C>G | synonymous_variant | 0.87 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674780 | c.579T>G | synonymous_variant | 0.86 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674799 | p.Ser200Ala | missense_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674804 | c.603G>A | synonymous_variant | 0.89 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674822 | c.621C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674840 | c.639C>G | synonymous_variant | 1.0 | ethionamide | |
| isoniazid | ||||||
| inhA | 1674870 | c.669T>C | synonymous_variant | 0.9 | ethionamide | |
| isoniazid | ||||||
| eis | 2715320 | c.13C>T | synonymous_variant | 0.12 | kanamycin | |
| amikacin | ||||||
| ethA | 4326145 | p.Leu443Ile | missense_variant | 0.99 | ethionamide | |
| ethA | 4326163 | c.1311T>C | synonymous_variant | 0.99 | ethionamide | |
| ethA | 4326166 | c.1308A>G | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326169 | c.1305C>T | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326184 | c.1290C>G | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326190 | c.1284G>A | synonymous_variant | 0.99 | ethionamide | |
| ethA | 4326193 | c.1281A>G | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326202 | p.Ser424Pro | missense_variant | 1.0 | ethionamide | |
| ethA | 4326205 | c.1269C>T | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326211 | p.Arg421His | missense_variant | 1.0 | ethionamide | |
| ethA | 4326218 | p.Val419Ala | missense_variant | 1.0 | ethionamide | |
| ethA | 4326220 | p.Val418Met | missense_variant | 1.0 | ethionamide | |
| ethA | 4326226 | c.1248C>G | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326238 | c.1236C>T | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326242 | p.Asp411Ala | missense_variant | 1.0 | ethionamide | |
| ethA | 4326253 | c.1221T>C | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326258 | c.1216T>C | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326261 | p.Leu405Val | missense_variant | 1.0 | ethionamide | |
| ethA | 4326262 | c.1212C>T | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326265 | c.1209T>C | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326271 | c.1203T>C | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326298 | c.1176G>C | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326304 | c.1170C>G | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326322 | c.1152T>C | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326331 | c.1143C>G | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326337 | c.1137C>T | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326343 | c.1131C>T | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326346 | c.1128C>G | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326352 | c.1122T>G | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326380 | p.Thr365Lys | missense_variant | 1.0 | ethionamide | |
| ethA | 4326387 | p.Ile363Leu | missense_variant | 0.99 | ethionamide | |
| ethA | 4326388 | c.1086C>T | synonymous_variant | 0.95 | ethionamide | |
| ethA | 4326436 | c.1038G>A | synonymous_variant | 0.91 | ethionamide | |
| ethA | 4326439 | c.1035C>T | synonymous_variant | 0.99 | ethionamide | |
| ethA | 4326445 | c.1029G>T | synonymous_variant | 0.99 | ethionamide | |
| ethA | 4326451 | c.1023A>G | synonymous_variant | 0.99 | ethionamide | |
| ethA | 4326457 | p.Ile339Val | missense_variant | 0.99 | ethionamide | |
| ethA | 4326469 | c.1005T>C | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326475 | c.999G>T | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326481 | c.993C>T | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326484 | c.990T>A | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326487 | c.987A>C | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326490 | c.984C>T | synonymous_variant | 0.99 | ethionamide | |
| ethA | 4326507 | p.Thr323Ala | missense_variant | 1.0 | ethionamide | |
| ethA | 4326508 | p.Ala322Pro | missense_variant | 1.0 | ethionamide | |
| ethA | 4326514 | c.960C>T | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326520 | p.Glu318Asp | missense_variant | 1.0 | ethionamide | |
| ethA | 4326523 | c.951T>C | synonymous_variant | 1.0 | ethionamide | |
| ethA | 4326535 | c.939G>C | synonymous_variant | 1.0 | ethionamide | |
| ethR | 4326556 | c.-993A>G | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326565 | c.-984C>A | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326591 | c.-958A>G | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326598 | c.-951T>C | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326610 | c.-939G>C | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326613 | c.-936G>A | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326628 | c.-921G>A | upstream_gene_variant | 0.99 | ethionamide | |
| ethR | 4326637 | c.-912T>G | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326640 | c.-909C>T | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326649 | c.-900C>A | upstream_gene_variant | 0.99 | ethionamide | |
| ethR | 4326652 | c.-897C>T | upstream_gene_variant | 0.99 | ethionamide | |
| ethR | 4326658 | c.-891T>C | upstream_gene_variant | 0.98 | ethionamide | |
| ethR | 4326661 | c.-888C>T | upstream_gene_variant | 0.99 | ethionamide | |
| ethR | 4326675 | c.-874G>A | upstream_gene_variant | 0.47 | ethionamide | |
| ethA | 4326678 | p.Ser266Gly | missense_variant | 1.0 | ethionamide | |
| ethA | 4326681 | p.Leu265Met | missense_variant | 0.99 | ethionamide | |
| ethR | 4326691 | c.-858C>G | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326697 | c.-852G>C | upstream_gene_variant | 1.0 | ethionamide | |
| ethR | 4326703 | c.-846T>C | upstream_gene_variant | 0.98 | ethionamide | |
| ethA | 4326721 | p.Ser251Gly | missense_variant | 0.99 | ethionamide | |
| ethR | 4326730 | c.-819G>C | upstream_gene_variant | 1.0 | ethionamide |
