TB-Profiler result

Run: SRR13861305
Summary

Run ID: SRR13861305

Sample name:

Date: 03-04-2023 09:28:31

Number of reads: 1033699

Percentage reads mapped: 34.49

Strain: lineage4.9

Drug-resistance: Other

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.27 streptomycin
embB 4247448 p.His312Arg missense_variant 0.12 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 6307 c.-995T>G upstream_gene_variant 0.14
gyrA 6319 c.-983G>C upstream_gene_variant 0.14
gyrA 6325 c.-977C>G upstream_gene_variant 0.19
gyrA 6361 c.-941G>A upstream_gene_variant 0.15
gyrA 6362 c.-940T>C upstream_gene_variant 0.15
gyrA 6379 c.-923C>G upstream_gene_variant 0.17
gyrA 6382 c.-920A>G upstream_gene_variant 0.15
gyrA 6388 c.-914T>C upstream_gene_variant 0.15
gyrB 6455 p.Val406Ile missense_variant 0.12
gyrA 6700 c.-602T>C upstream_gene_variant 0.15
gyrA 6703 c.-599G>C upstream_gene_variant 0.16
gyrA 6706 c.-596G>A upstream_gene_variant 0.16
gyrA 6709 c.-593A>G upstream_gene_variant 0.15
gyrA 6727 c.-575G>T upstream_gene_variant 0.16
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.16
gyrA 6745 c.-557T>G upstream_gene_variant 0.18
gyrA 6760 c.-542G>C upstream_gene_variant 0.18
gyrA 6778 c.-524C>T upstream_gene_variant 0.17
gyrA 6793 c.-509T>C upstream_gene_variant 0.17
gyrB 6797 p.Gly520Thr missense_variant 0.17
gyrA 7466 c.165G>A synonymous_variant 0.14
gyrA 7469 c.168C>T synonymous_variant 0.14
gyrA 7480 p.Phe60Tyr missense_variant 0.14
gyrA 7490 c.189C>T synonymous_variant 0.14
gyrA 7541 c.240C>G synonymous_variant 0.15
gyrA 7626 c.325C>T synonymous_variant 0.15
gyrA 7637 c.336C>G synonymous_variant 0.15
gyrA 7649 c.348C>T synonymous_variant 0.19
gyrA 7652 c.351C>T synonymous_variant 0.19
gyrA 7658 c.357A>G synonymous_variant 0.22
gyrA 7664 c.363T>C synonymous_variant 0.21
gyrA 7670 c.369A>G synonymous_variant 0.18
gyrA 7676 c.375G>C synonymous_variant 0.18
gyrA 7683 c.382A>C synonymous_variant 0.18
gyrA 7694 c.393A>G synonymous_variant 0.17
gyrA 7697 c.396C>G synonymous_variant 0.19
gyrA 7710 c.409T>C synonymous_variant 0.28
gyrA 7715 c.414G>C synonymous_variant 0.31
gyrA 7728 c.427_429delAGGinsCGC synonymous_variant 0.3
gyrA 7760 c.459C>T synonymous_variant 0.27
gyrA 7763 c.462T>C synonymous_variant 0.26
gyrA 7799 c.498A>G synonymous_variant 0.24
gyrA 7835 c.534A>G synonymous_variant 0.22
gyrA 7838 c.537C>G synonymous_variant 0.22
gyrA 7859 c.558A>C synonymous_variant 0.15
gyrA 7862 c.561C>G synonymous_variant 0.17
gyrA 7865 c.564T>C synonymous_variant 0.14
gyrA 7919 p.Glu206Asp missense_variant 0.14
gyrA 8786 c.1485T>C synonymous_variant 0.15
gyrA 9566 c.2265C>T synonymous_variant 0.13
gyrA 9605 c.2304C>G synonymous_variant 0.21
gyrA 9611 p.Asp770Glu missense_variant 0.21
gyrA 9626 c.2325T>C synonymous_variant 0.23
gyrA 9629 c.2328C>G synonymous_variant 0.23
gyrA 9630 p.Val777Ile missense_variant 0.23
gyrA 9635 c.2334T>C synonymous_variant 0.23
gyrA 9644 c.2343T>C synonymous_variant 0.22
gyrA 9647 c.2346C>T synonymous_variant 0.21
gyrA 9650 c.2349G>C synonymous_variant 0.21
gyrA 9665 c.2364A>G synonymous_variant 0.21
gyrA 9666 p.Arg789Gly missense_variant 0.21
gyrA 9674 c.2373T>C synonymous_variant 0.2
gyrA 9677 c.2376C>T synonymous_variant 0.2
gyrA 9701 c.2400T>C synonymous_variant 0.16
fgd1 491181 c.399T>C synonymous_variant 0.16
fgd1 491191 p.Gly137Arg missense_variant 0.16
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.16
fgd1 491232 c.450T>C synonymous_variant 0.2
fgd1 491241 p.Asp153Glu missense_variant 0.18
fgd1 491244 c.462T>C synonymous_variant 0.16
fgd1 491259 c.477T>C synonymous_variant 0.15
fgd1 491296 p.Val172Ile missense_variant 0.14
fgd1 491301 c.519C>T synonymous_variant 0.13
rpoB 760121 c.315T>C synonymous_variant 0.14
rpoB 760139 c.333A>G synonymous_variant 0.14
rpoB 760142 c.336C>G synonymous_variant 0.14
rpoB 760181 c.375T>C synonymous_variant 0.14
rpoB 760184 c.378A>G synonymous_variant 0.15
rpoB 760196 c.390C>G synonymous_variant 0.16
rpoB 760340 c.534G>C synonymous_variant 0.16
rpoB 760361 c.555T>C synonymous_variant 0.18
rpoB 760728 p.Tyr308Asn missense_variant 0.92
rpoB 760985 c.1179G>C synonymous_variant 0.16
rpoB 760991 c.1185G>C synonymous_variant 0.16
rpoB 761015 c.1209G>C synonymous_variant 0.16
rpoB 761021 c.1215G>C synonymous_variant 0.16
rpoB 761027 c.1221A>G synonymous_variant 0.15
rpoB 761094 c.1288C>T synonymous_variant 0.14
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.14
rpoB 761102 c.1296A>G synonymous_variant 0.17
rpoB 761133 c.1327T>C synonymous_variant 0.15
rpoB 761150 c.1344A>C synonymous_variant 0.15
rpoB 761222 c.1416G>C synonymous_variant 0.18
rpoB 761249 c.1443A>G synonymous_variant 0.15
rpoB 761261 c.1455G>T synonymous_variant 0.15
rpoB 761570 c.1764T>C synonymous_variant 0.14
rpoB 761579 c.1773G>C synonymous_variant 0.16
rpoB 761606 c.1800C>G synonymous_variant 0.18
rpoB 761612 c.1806G>C synonymous_variant 0.15
rpoB 761615 c.1809A>C synonymous_variant 0.14
rpoB 761648 c.1842T>C synonymous_variant 0.16
rpoB 761657 c.1851C>G synonymous_variant 0.16
rpoB 761675 c.1869G>C synonymous_variant 0.15
rpoB 761687 c.1881C>T synonymous_variant 0.15
rpoB 761690 c.1884G>C synonymous_variant 0.16
rpoB 761732 c.1926C>G synonymous_variant 0.19
rpoB 761735 c.1929C>G synonymous_variant 0.17
rpoB 761747 c.1941G>C synonymous_variant 0.19
rpoB 761750 c.1944G>C synonymous_variant 0.19
rpoB 761765 c.1959T>C synonymous_variant 0.2
rpoB 761772 p.His656Ala missense_variant 0.23
rpoB 761778 p.Asn658Asp missense_variant 0.21
rpoB 761791 p.Arg662His missense_variant 0.15
rpoB 761813 c.2007T>C synonymous_variant 0.14
rpoB 761815 p.Ala670Glu missense_variant 0.14
rpoB 761834 c.2028T>C synonymous_variant 0.16
rpoB 761847 p.Cys681Ser missense_variant 0.17
rpoB 761852 c.2046C>G synonymous_variant 0.2
rpoB 761858 c.2052G>C synonymous_variant 0.23
rpoB 761864 c.2058G>C synonymous_variant 0.26
rpoB 761873 c.2067A>G synonymous_variant 0.22
rpoB 761885 c.2079T>C synonymous_variant 0.22
rpoB 761891 c.2085G>C synonymous_variant 0.19
rpoB 761906 c.2100C>G synonymous_variant 0.19
rpoB 761909 c.2103T>C synonymous_variant 0.19
rpoB 761912 c.2106T>C synonymous_variant 0.19
rpoB 761915 p.Asp703Glu missense_variant 0.19
rpoB 761916 p.Asp704Asn missense_variant 0.19
rpoB 761948 c.2142G>C synonymous_variant 0.18
rpoB 761954 c.2148C>G synonymous_variant 0.19
rpoB 761999 c.2193G>C synonymous_variant 0.16
rpoB 762254 c.2448T>C synonymous_variant 0.14
rpoB 762266 c.2460T>C synonymous_variant 0.15
rpoB 762284 c.2478G>C synonymous_variant 0.17
rpoB 762293 c.2487T>C synonymous_variant 0.16
rpoB 762317 c.2511A>G synonymous_variant 0.17
rpoB 762329 c.2523G>C synonymous_variant 0.15
rpoB 762338 c.2532T>C synonymous_variant 0.15
rpoB 762347 c.2541T>C synonymous_variant 0.15
rpoC 762929 c.-441G>C upstream_gene_variant 0.14
rpoC 762989 c.-381G>C upstream_gene_variant 0.14
rpoC 763456 c.87A>G synonymous_variant 0.17
rpoC 763468 c.99G>C synonymous_variant 0.19
rpoC 763486 c.117T>C synonymous_variant 0.18
rpoC 763528 c.159G>A synonymous_variant 0.24
rpoC 763546 c.177A>G synonymous_variant 0.24
rpoC 763570 c.201G>C synonymous_variant 0.26
rpoC 763594 c.225C>T synonymous_variant 0.31
rpoC 763633 c.264T>C synonymous_variant 0.29
rpoC 763636 c.267T>C synonymous_variant 0.27
rpoC 763642 c.273G>C synonymous_variant 0.26
rpoC 763658 c.289_291delCTTinsTTG synonymous_variant 0.19
rpoC 763675 c.306C>G synonymous_variant 0.21
rpoC 763696 c.327T>C synonymous_variant 0.2
rpoC 763702 c.333C>G synonymous_variant 0.2
rpoC 763708 c.339G>A synonymous_variant 0.19
rpoC 763709 c.340C>T synonymous_variant 0.19
rpoC 763714 c.345G>C synonymous_variant 0.18
rpoC 763717 c.348T>C synonymous_variant 0.18
rpoC 763723 c.354G>C synonymous_variant 0.2
rpoC 763732 c.363C>G synonymous_variant 0.19
rpoC 763735 c.366G>C synonymous_variant 0.19
rpoC 763744 c.375G>C synonymous_variant 0.16
rpoC 763765 c.396T>C synonymous_variant 0.14
rpoC 763768 c.399C>G synonymous_variant 0.14
rpoC 763928 p.Glu187* stop_gained 0.9
rpoC 764131 c.762T>C synonymous_variant 0.19
rpoC 764161 c.792G>C synonymous_variant 0.16
rpoC 764188 c.819A>G synonymous_variant 0.17
rpoC 764195 p.Ser276Gln missense_variant 0.14
rpoC 764203 c.834G>T synonymous_variant 0.15
rpoC 764206 c.837T>C synonymous_variant 0.14
rpoC 764626 c.1257C>T synonymous_variant 0.21
rpoC 764632 c.1263T>C synonymous_variant 0.2
rpoC 764644 c.1275G>C synonymous_variant 0.17
rpoC 764650 c.1281G>T synonymous_variant 0.17
rpoC 764714 c.1345C>T synonymous_variant 0.21
rpoC 764720 c.1351C>T synonymous_variant 0.19
rpoC 764752 c.1383G>C synonymous_variant 0.16
rpoC 764764 c.1395T>C synonymous_variant 0.19
rpoC 764791 c.1422C>G synonymous_variant 0.18
rpoC 764809 c.1440C>T synonymous_variant 0.18
rpoC 764812 c.1443C>G synonymous_variant 0.18
rpoC 764815 c.1446A>G synonymous_variant 0.18
rpoC 764824 c.1455T>C synonymous_variant 0.19
rpoC 764830 c.1461C>G synonymous_variant 0.19
rpoC 764858 c.1489T>C synonymous_variant 0.17
rpoC 764872 c.1503A>G synonymous_variant 0.16
rpoC 764893 c.1524T>C synonymous_variant 0.2
rpoC 764911 c.1542A>G synonymous_variant 0.23
rpoC 764923 c.1554A>G synonymous_variant 0.19
rpoC 764932 c.1563C>A synonymous_variant 0.2
rpoC 764968 c.1599T>C synonymous_variant 0.2
rpoC 764995 c.1626C>G synonymous_variant 0.22
rpoC 765007 c.1638T>G synonymous_variant 0.21
rpoC 765019 c.1650A>G synonymous_variant 0.17
rpoC 765022 c.1653G>C synonymous_variant 0.17
rpoC 765404 p.Leu679Val missense_variant 0.16
rpoC 765478 c.2109T>C synonymous_variant 0.19
rpoC 765499 c.2130C>G synonymous_variant 0.15
rpoC 765541 c.2172C>G synonymous_variant 0.16
rpoC 765578 c.2209C>T synonymous_variant 0.16
rpoC 765583 c.2214G>T synonymous_variant 0.16
rpoC 765613 p.His748Gln missense_variant 0.17
rpoC 765625 c.2256C>G synonymous_variant 0.15
rpoC 765628 c.2259G>C synonymous_variant 0.15
rpoC 765631 p.Asp754Glu missense_variant 0.15
rpoC 765658 c.2289C>T synonymous_variant 0.22
rpoC 765700 c.2331T>C synonymous_variant 0.26
rpoC 765734 c.2365T>C synonymous_variant 0.26
rpoC 765739 c.2370G>C synonymous_variant 0.25
rpoC 765751 c.2382C>G synonymous_variant 0.26
rpoC 765753 p.Asp795Ala missense_variant 0.26
rpoC 765772 c.2403C>G synonymous_variant 0.29
rpoC 765784 c.2415C>G synonymous_variant 0.28
rpoC 765796 c.2427C>T synonymous_variant 0.24
rpoC 765811 c.2442T>C synonymous_variant 0.19
rpoC 765814 c.2445A>G synonymous_variant 0.23
rpoC 765826 c.2457T>C synonymous_variant 0.26
rpoC 765835 c.2466C>T synonymous_variant 0.24
rpoC 765883 c.2514C>G synonymous_variant 0.21
rpoC 765886 c.2517C>G synonymous_variant 0.22
rpoC 765892 c.2523T>C synonymous_variant 0.24
rpoC 765928 c.2559C>G synonymous_variant 0.21
rpoC 765967 c.2598C>T synonymous_variant 0.19
rpoC 765970 c.2601C>T synonymous_variant 0.17
rpoC 765979 c.2610C>G synonymous_variant 0.18
rpoC 765982 c.2613C>T synonymous_variant 0.18
rpoC 765985 c.2616C>T synonymous_variant 0.17
rpoC 765994 c.2625A>T synonymous_variant 0.18
rpoC 766009 c.2640G>C synonymous_variant 0.16
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.16
rpoC 766021 c.2652G>C synonymous_variant 0.18
rpoC 766155 p.Ala929Val missense_variant 0.95
rpoC 766381 c.3012C>T synonymous_variant 0.15
rpoC 766384 c.3015A>G synonymous_variant 0.16
rpoC 766390 c.3021C>T synonymous_variant 0.19
rpoC 766408 c.3039C>T synonymous_variant 0.21
rpoC 766426 c.3057C>T synonymous_variant 0.26
rpoC 766447 c.3078T>C synonymous_variant 0.27
rpoC 766483 c.3114G>C synonymous_variant 0.26
rpoC 766484 p.Val1039Ile missense_variant 0.26
rpoC 766492 c.3123T>C synonymous_variant 0.26
rpoC 766495 c.3126C>T synonymous_variant 0.28
rpoC 766522 c.3153C>G synonymous_variant 0.26
rpoC 766528 c.3159T>C synonymous_variant 0.28
rpoC 766531 c.3162G>T synonymous_variant 0.27
rpoC 766543 c.3174C>T synonymous_variant 0.25
rpoC 766549 c.3180G>C synonymous_variant 0.23
rpoC 766609 p.Ile1080Met missense_variant 0.15
rpoC 766630 c.3261G>C synonymous_variant 0.17
rpoC 766645 c.3276A>G synonymous_variant 0.19
rpoC 766651 c.3282T>C synonymous_variant 0.19
rpoC 766657 c.3288A>G synonymous_variant 0.2
rpoC 766672 c.3303T>C synonymous_variant 0.19
rpoC 766726 c.3357T>C synonymous_variant 0.15
rpoC 766738 c.3369G>T synonymous_variant 0.16
rpoC 766750 c.3381C>G synonymous_variant 0.19
rpoC 766765 c.3396A>C synonymous_variant 0.17
rpoC 766774 c.3405T>C synonymous_variant 0.21
rpoC 766801 c.3432C>A synonymous_variant 0.17
rpoC 766804 c.3435A>G synonymous_variant 0.17
rpoC 766843 c.3474T>C synonymous_variant 0.21
rpoC 766861 c.3492G>C synonymous_variant 0.19
rpoC 766864 c.3495G>C synonymous_variant 0.19
rpoC 766894 c.3525T>C synonymous_variant 0.17
rpoC 766895 c.3526T>C synonymous_variant 0.17
rpoC 766900 c.3531T>C synonymous_variant 0.15
rpoC 766933 c.3564A>G synonymous_variant 0.16
rpoC 766963 c.3594T>C synonymous_variant 0.14
rpoC 766978 c.3609C>G synonymous_variant 0.14
mmpL5 777185 c.1296G>T synonymous_variant 1.0
rpsL 781682 c.123T>C synonymous_variant 0.15
rpsL 781715 c.156T>C synonymous_variant 0.19
rpsL 781728 c.169T>C synonymous_variant 0.2
rpsL 781736 c.177T>C synonymous_variant 0.2
rpsL 781751 c.192G>C synonymous_variant 0.19
rpsL 781754 c.195G>C synonymous_variant 0.18
rpsL 781760 c.201T>C synonymous_variant 0.2
rpsL 781793 c.234G>C synonymous_variant 0.19
rpsL 781832 c.273T>C synonymous_variant 0.17
rpsL 781841 c.282C>G synonymous_variant 0.17
rpsL 781868 c.309T>C synonymous_variant 0.17
rpsL 781871 c.312G>C synonymous_variant 0.17
rpsL 781892 c.333A>G synonymous_variant 0.18
rpsL 781898 c.339A>T synonymous_variant 0.18
rpsL 781916 c.357T>C synonymous_variant 0.16
rpsL 781929 p.Gly124Ser missense_variant 0.18
rplC 800612 c.-197A>G upstream_gene_variant 0.23
rplC 800618 c.-191T>C upstream_gene_variant 0.24
rplC 800648 c.-161A>C upstream_gene_variant 0.26
rplC 800654 c.-155T>C upstream_gene_variant 0.26
rplC 800693 c.-116A>G upstream_gene_variant 0.24
rplC 800703 c.-106T>C upstream_gene_variant 0.19
rplC 800715 c.-94A>C upstream_gene_variant 0.19
rplC 800720 c.-89T>C upstream_gene_variant 0.2
rplC 800723 c.-86C>G upstream_gene_variant 0.18
rplC 800738 c.-71T>C upstream_gene_variant 0.16
rplC 800747 c.-62C>G upstream_gene_variant 0.18
rplC 800771 c.-38C>T upstream_gene_variant 0.2
rplC 800814 c.6A>G synonymous_variant 0.18
rplC 800817 c.9A>T synonymous_variant 0.19
rplC 800844 c.36T>C synonymous_variant 0.17
rplC 800865 c.57A>G synonymous_variant 0.16
rplC 800867 p.Ser20Asn missense_variant 0.17
rplC 800874 c.66A>G synonymous_variant 0.17
rplC 800877 c.69A>C synonymous_variant 0.17
rplC 800880 c.72A>G synonymous_variant 0.17
rplC 800889 c.81C>G synonymous_variant 0.16
rplC 800939 p.Arg44His missense_variant 0.13
rplC 800982 c.174C>T synonymous_variant 0.14
fbiC 1302932 p.Val1Gly missense_variant 1.0
fbiC 1303151 p.Gly74Asp missense_variant 1.0
fbiC 1304811 c.1881C>G synonymous_variant 0.14
fbiC 1304817 c.1887T>C synonymous_variant 0.14
fbiC 1304832 c.1902C>G synonymous_variant 0.15
fbiC 1304872 c.1942_1944delAGCinsTCG synonymous_variant 0.15
fbiC 1304877 c.1947T>C synonymous_variant 0.15
fbiC 1304878 c.1948_1950delCGCinsAGG synonymous_variant 0.15
fbiC 1304893 p.Gly655Arg missense_variant 0.18
fbiC 1304925 c.1995G>C synonymous_variant 0.15
fbiC 1304928 c.1998T>C synonymous_variant 0.16
fbiC 1304934 c.2004C>G synonymous_variant 0.15
fbiC 1305298 p.Lys790Gln missense_variant 0.95
Rv1258c 1406311 c.1030C>T synonymous_variant 1.0
atpE 1461132 p.Val30Ile missense_variant 0.14
atpE 1461149 c.105T>G synonymous_variant 0.17
atpE 1461150 p.Ile36Val missense_variant 0.17
atpE 1461159 p.Val39Ile missense_variant 0.16
atpE 1461185 c.141G>C synonymous_variant 0.16
atpE 1461189 c.145C>T synonymous_variant 0.17
atpE 1461194 c.150C>T synonymous_variant 0.15
atpE 1461197 c.153A>G synonymous_variant 0.15
atpE 1461219 c.175T>C synonymous_variant 0.15
atpE 1461224 c.180T>C synonymous_variant 0.14
atpE 1461233 c.189A>G synonymous_variant 0.15
rrs 1472028 n.183A>T non_coding_transcript_exon_variant 0.14
rrs 1472030 n.185G>A non_coding_transcript_exon_variant 0.14
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.15
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.14
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.15
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.14
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.12
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.19
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.17
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.15
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.15
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.16
inhA 1674507 c.306G>C synonymous_variant 0.18
inhA 1674537 c.336C>G synonymous_variant 0.17
inhA 1674542 p.Ala114Glu missense_variant 0.18
inhA 1674549 c.348G>C synonymous_variant 0.17
inhA 1674555 c.354G>A synonymous_variant 0.17
inhA 1674561 c.360C>T synonymous_variant 0.17
inhA 1674564 c.363C>T synonymous_variant 0.17
inhA 1674582 c.381T>C synonymous_variant 0.18
inhA 1674585 c.384T>C synonymous_variant 0.17
inhA 1674589 p.Met130Leu missense_variant 0.19
inhA 1674624 c.423A>C synonymous_variant 0.14
inhA 1674627 c.426T>G synonymous_variant 0.15
inhA 1674630 c.429C>G synonymous_variant 0.15
inhA 1674743 p.Lys181Thr missense_variant 0.15
rpsA 1833541 c.-1T>C upstream_gene_variant 0.14
rpsA 1833589 c.48A>T synonymous_variant 0.14
rpsA 1833595 c.54T>C synonymous_variant 0.18
rpsA 1833619 c.78A>C synonymous_variant 0.24
rpsA 1833661 c.120A>G synonymous_variant 0.21
rpsA 1833667 c.126C>G synonymous_variant 0.18
rpsA 1833724 c.183C>G synonymous_variant 0.18
rpsA 1833727 c.186G>C synonymous_variant 0.19
rpsA 1833742 c.201A>G synonymous_variant 0.2
rpsA 1833745 c.204G>C synonymous_variant 0.17
rpsA 1833787 c.246C>G synonymous_variant 0.19
rpsA 1833790 c.249T>A synonymous_variant 0.19
rpsA 1833799 c.258C>G synonymous_variant 0.19
rpsA 1833811 c.270G>C synonymous_variant 0.15
rpsA 1833874 c.333T>C synonymous_variant 0.17
rpsA 1833940 c.399C>G synonymous_variant 0.16
rpsA 1833970 c.429G>C synonymous_variant 0.16
rpsA 1833979 c.438T>C synonymous_variant 0.16
rpsA 1834000 c.459G>C synonymous_variant 0.15
rpsA 1834015 c.474G>C synonymous_variant 0.17
rpsA 1834021 c.480C>T synonymous_variant 0.14
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 0.16
rpsA 1834102 c.561T>C synonymous_variant 0.14
rpsA 1834275 p.Ile245Thr missense_variant 1.0
rpsA 1834546 c.1005T>C synonymous_variant 0.16
rpsA 1834555 c.1014T>C synonymous_variant 0.15
rpsA 1834606 c.1065C>G synonymous_variant 0.15
rpsA 1834609 c.1068T>C synonymous_variant 0.19
rpsA 1834622 c.1081_1083delTCGinsAGC synonymous_variant 0.17
rpsA 1834633 c.1092A>G synonymous_variant 0.24
rpsA 1834639 c.1098T>C synonymous_variant 0.24
rpsA 1834666 c.1125G>C synonymous_variant 0.23
rpsA 1834669 c.1128G>C synonymous_variant 0.23
rpsA 1834688 c.1147_1149delAGTinsTCC synonymous_variant 0.2
rpsA 1834732 c.1191T>C synonymous_variant 0.24
rpsA 1834733 p.Ala398Pro missense_variant 0.25
rpsA 1834753 c.1212T>C synonymous_variant 0.24
rpsA 1834765 c.1224A>G synonymous_variant 0.21
rpsA 1834792 c.1251G>C synonymous_variant 0.14
tlyA 1917936 c.-4C>A upstream_gene_variant 1.0
ndh 2101676 p.Ala456Val missense_variant 1.0
pncA 2289356 c.-115G>T upstream_gene_variant 1.0
kasA 2518234 p.Glu40Asp missense_variant 1.0
ahpC 2726638 p.Ala149Val missense_variant 0.14
ahpC 2726657 c.465A>C synonymous_variant 0.14
Rv2752c 3064837 p.Leu452Trp missense_variant 0.97
thyX 3067304 c.642A>G synonymous_variant 0.15
thyX 3067316 c.630A>G synonymous_variant 0.14
thyX 3067325 c.621A>G synonymous_variant 0.15
thyX 3067355 c.591A>C synonymous_variant 0.14
thyX 3067367 c.579G>C synonymous_variant 0.2
thyX 3067376 c.570G>C synonymous_variant 0.18
thyX 3067391 c.555G>C synonymous_variant 0.18
thyX 3067394 c.552G>C synonymous_variant 0.19
thyX 3067412 c.534C>G synonymous_variant 0.22
thyX 3067439 c.507A>G synonymous_variant 0.19
thyX 3067445 c.501C>G synonymous_variant 0.17
thyX 3067451 c.495G>A synonymous_variant 0.17
thyX 3067457 c.489C>G synonymous_variant 0.15
thyX 3067465 p.Ile161Val missense_variant 0.15
thyX 3067466 c.480G>C synonymous_variant 0.15
thyA 3073839 c.633T>C synonymous_variant 0.14
thyA 3073872 p.Ile200Val missense_variant 0.18
thyA 3073878 c.594G>A synonymous_variant 0.17
thyA 3073892 c.580T>C synonymous_variant 0.19
thyA 3073893 c.579C>G synonymous_variant 0.19
thyA 3073925 c.547T>C synonymous_variant 0.2
thyA 3073926 c.546G>C synonymous_variant 0.21
thyA 3073929 c.543T>C synonymous_variant 0.23
thyA 3073953 c.519T>C synonymous_variant 0.16
thyA 3073989 c.483T>C synonymous_variant 0.15
thyA 3074004 c.468T>C synonymous_variant 0.14
thyA 3074031 c.441T>C synonymous_variant 0.14
thyA 3074097 c.375C>G synonymous_variant 0.19
thyA 3074100 c.372T>C synonymous_variant 0.16
thyA 3074106 c.366T>C synonymous_variant 0.17
thyA 3074117 c.355C>T synonymous_variant 0.16
thyA 3074120 c.352T>C synonymous_variant 0.15
thyA 3074130 c.342G>C synonymous_variant 0.15
Rv3083 3449643 p.Asn380Lys missense_variant 1.0
fprA 3474752 p.Ile249Ser missense_variant 1.0
fprA 3475315 p.His437Asn missense_variant 1.0
Rv3236c 3611967 p.Ser384Pro missense_variant 1.0
fbiB 3642581 c.1047A>C synonymous_variant 0.24
fbiB 3642593 c.1059G>C synonymous_variant 0.25
fbiB 3642602 c.1068A>C synonymous_variant 0.24
fbiB 3642605 c.1071A>G synonymous_variant 0.25
fbiB 3642614 c.1080C>T synonymous_variant 0.24
fbiB 3642620 c.1086T>C synonymous_variant 0.27
fbiB 3642656 c.1122G>C synonymous_variant 0.25
fbiB 3642659 c.1125C>G synonymous_variant 0.24
fbiB 3642662 c.1128C>G synonymous_variant 0.21
fbiB 3642668 c.1134A>C synonymous_variant 0.24
fbiB 3642677 c.1143A>G synonymous_variant 0.24
fbiB 3642680 c.1146A>G synonymous_variant 0.27
fbiB 3642684 c.1150T>C synonymous_variant 0.24
fbiB 3642694 p.Ala387Gly missense_variant 0.23
fbiB 3642696 c.1162C>T synonymous_variant 0.24
fbiB 3642701 c.1167C>G synonymous_variant 0.23
fbiB 3642710 c.1176G>C synonymous_variant 0.21
fbiB 3642719 c.1185T>C synonymous_variant 0.17
rpoA 3877743 c.765T>C synonymous_variant 0.19
rpoA 3877756 p.Ile251Thr missense_variant 0.84
rpoA 3877764 c.744C>G synonymous_variant 0.15
rpoA 3877770 c.738A>G synonymous_variant 0.15
rpoA 3877776 c.732T>C synonymous_variant 0.15
rpoA 3877818 c.690A>G synonymous_variant 0.16
rpoA 3877839 c.669G>C synonymous_variant 0.17
rpoA 3877857 c.651G>A synonymous_variant 0.22
rpoA 3877866 c.642G>C synonymous_variant 0.21
rpoA 3877872 c.636C>T synonymous_variant 0.24
rpoA 3877875 c.633T>G synonymous_variant 0.19
rpoA 3877899 p.Ser203Thr missense_variant 0.22
rpoA 3877905 c.603A>G synonymous_variant 0.21
rpoA 3877908 p.Asn200Ser missense_variant 0.21
rpoA 3877953 c.555G>A synonymous_variant 0.21
rpoA 3877962 c.546G>T synonymous_variant 0.21
rpoA 3877986 c.522G>C synonymous_variant 0.24
rpoA 3877989 c.519A>G synonymous_variant 0.23
rpoA 3878001 c.507A>G synonymous_variant 0.17
rpoA 3878065 p.Pro148Arg missense_variant 0.88
ddn 3986648 c.-196C>G upstream_gene_variant 0.17
ddn 3986655 c.-189A>T upstream_gene_variant 0.18
ddn 3986660 c.-184C>T upstream_gene_variant 0.17
ddn 3986665 c.-179G>C upstream_gene_variant 0.17
ddn 3986667 c.-177_-176delCTinsAC upstream_gene_variant 0.17
ddn 3986681 c.-163C>G upstream_gene_variant 0.18
ddn 3986696 c.-148G>T upstream_gene_variant 0.13
ddn 3986977 p.Pro45Arg missense_variant 1.0
clpC1 4038368 c.2337T>C synonymous_variant 0.14
clpC1 4038398 c.2307G>T synonymous_variant 0.16
clpC1 4038403 c.2302T>C synonymous_variant 0.19
clpC1 4038419 c.2286T>C synonymous_variant 0.17
clpC1 4038434 c.2271G>C synonymous_variant 0.17
clpC1 4038444 p.Ala754Lys missense_variant 0.18
clpC1 4038446 c.2259T>C synonymous_variant 0.18
clpC1 4038452 c.2253G>C synonymous_variant 0.18
clpC1 4038461 p.Ala748Asp missense_variant 0.17
clpC1 4038782 c.1923G>C synonymous_variant 0.14
clpC1 4039388 c.1317C>A synonymous_variant 0.14
clpC1 4039391 c.1314T>G synonymous_variant 0.15
clpC1 4039409 c.1296T>C synonymous_variant 0.21
clpC1 4039412 c.1293T>G synonymous_variant 0.2
clpC1 4039430 c.1275T>C synonymous_variant 0.21
clpC1 4039442 c.1263A>G synonymous_variant 0.24
clpC1 4039448 c.1257A>G synonymous_variant 0.23
clpC1 4039454 c.1251A>G synonymous_variant 0.21
clpC1 4039463 c.1242C>G synonymous_variant 0.18
clpC1 4039466 c.1239T>C synonymous_variant 0.18
clpC1 4039469 c.1236T>C synonymous_variant 0.18
clpC1 4039481 c.1224T>G synonymous_variant 0.2
clpC1 4039484 c.1221T>G synonymous_variant 0.2
clpC1 4039517 c.1188C>G synonymous_variant 0.22
clpC1 4039524 p.Phe394Tyr missense_variant 0.21
clpC1 4039526 c.1179G>C synonymous_variant 0.21
clpC1 4039547 c.1158C>G synonymous_variant 0.15
clpC1 4039553 c.1152C>G synonymous_variant 0.15
clpC1 4039562 c.1143C>G synonymous_variant 0.17
clpC1 4039565 c.1140G>C synonymous_variant 0.2
clpC1 4039576 p.Ala377Ser missense_variant 0.18
clpC1 4039577 c.1128T>C synonymous_variant 0.17
clpC1 4039586 c.1119G>C synonymous_variant 0.19
clpC1 4039610 c.1095G>C synonymous_variant 0.21
clpC1 4039616 c.1089G>C synonymous_variant 0.18
clpC1 4039622 c.1083C>G synonymous_variant 0.17
clpC1 4039682 c.1023C>G synonymous_variant 0.15
clpC1 4039685 c.1020C>T synonymous_variant 0.15
clpC1 4039694 c.1011G>C synonymous_variant 0.15
clpC1 4040273 c.432T>C synonymous_variant 0.14
clpC1 4040354 c.351A>G synonymous_variant 0.17
clpC1 4040363 c.342A>C synonymous_variant 0.17
clpC1 4040369 c.336C>G synonymous_variant 0.18
clpC1 4040380 c.325T>C synonymous_variant 0.2
clpC1 4040381 c.324T>C synonymous_variant 0.2
clpC1 4040387 c.318A>G synonymous_variant 0.2
clpC1 4040393 c.312G>C synonymous_variant 0.18
clpC1 4040411 c.294T>C synonymous_variant 0.16
clpC1 4040538 p.Leu56Arg missense_variant 0.92
embC 4240123 c.261C>G synonymous_variant 0.14
embC 4240687 c.825C>G synonymous_variant 0.15
embC 4240693 c.831T>C synonymous_variant 0.16
embC 4240706 p.Val282Thr missense_variant 0.15
embC 4240726 c.864G>C synonymous_variant 0.17
embC 4240819 c.957A>G synonymous_variant 0.15
embC 4240825 c.963G>A synonymous_variant 0.17
embC 4240831 c.969T>G synonymous_variant 0.16
embC 4240880 p.Ala340Thr missense_variant 0.13
embC 4241035 c.1173G>A synonymous_variant 0.13
embC 4241689 c.1827G>C synonymous_variant 0.16
embC 4241691 p.Gly610Ala missense_variant 0.15
embC 4241695 c.1833T>G synonymous_variant 0.15
embC 4241707 c.1845G>C synonymous_variant 0.14
embC 4241746 c.1884C>T synonymous_variant 0.14
embC 4241747 p.Val629Leu missense_variant 0.14
embC 4241770 c.1908T>C synonymous_variant 0.15
embC 4241791 c.1929G>C synonymous_variant 0.15
embA 4245342 p.Ser704Pro missense_variant 1.0
embB 4245764 c.-750G>C upstream_gene_variant 0.16
embA 4245771 p.Asn847Ser missense_variant 0.17
embB 4245807 c.-707_-705delTTAinsCTG upstream_gene_variant 0.19
embA 4245820 p.Ser863Thr missense_variant 0.17
embB 4245830 c.-684G>C upstream_gene_variant 0.18
embB 4245845 c.-669T>G upstream_gene_variant 0.15
embB 4245848 c.-666C>G upstream_gene_variant 0.15
embB 4247317 c.804G>C synonymous_variant 0.13
embB 4247326 c.813A>G synonymous_variant 0.14
embB 4247328 p.Ser272Asn missense_variant 0.14
embB 4247338 c.825C>G synonymous_variant 0.17
embB 4248711 c.2198_2199insT frameshift_variant 1.0
aftB 4267498 p.Glu447Lys missense_variant 0.97
aftB 4268559 p.Leu93Gln missense_variant 1.0