TB-Profiler result

Run: SRR1791899
Summary

Run ID: SRR1791899

Sample name:

Date: 03-04-2023 18:33:56

Number of reads: 141200

Percentage reads mapped: 24.94

Strain: La1.8.1

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
La1 M.bovis None None 1.0
La1.8 M.bovis None None 1.0
La1.8.1 M.bovis None None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
tlyA 1918255 c.319delC frameshift_variant 0.33 capreomycin
katG 2154109 p.Trp668* stop_gained 0.4 isoniazid
katG 2155751 p.Gly121Cys missense_variant 0.2 isoniazid
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
gid 4408094 p.Gly37* stop_gained 0.22 streptomycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5104 c.-136C>A upstream_gene_variant 0.33
gyrB 5419 c.180T>C synonymous_variant 0.11
gyrB 5462 p.Val75Ile missense_variant 0.13
gyrB 5731 c.492C>A synonymous_variant 0.29
gyrB 5752 c.513G>A synonymous_variant 1.0
gyrB 5951 p.Ala238Pro missense_variant 1.0
gyrB 6005 p.Gly256Cys missense_variant 0.14
gyrB 6343 p.Glu368Asp missense_variant 0.22
gyrA 6406 c.-896C>T upstream_gene_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7668 p.Pro123Thr missense_variant 0.17
gyrA 7770 p.Asp157Asn missense_variant 0.14
gyrA 8285 c.984C>T synonymous_variant 1.0
gyrA 8696 c.1395G>T synonymous_variant 0.33
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9217 p.Asp639Ala missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9761 c.2460A>G synonymous_variant 0.5
fgd1 490669 c.-114C>T upstream_gene_variant 0.22
fgd1 490936 p.Pro52Ser missense_variant 0.33
fgd1 491121 c.339A>G synonymous_variant 0.18
fgd1 491677 p.Gln299Lys missense_variant 0.29
fgd1 491742 c.960T>C synonymous_variant 1.0
ccsA 620632 p.Ala248Ser missense_variant 0.4
rpoB 759741 c.-66C>T upstream_gene_variant 0.25
rpoB 760185 p.Leu127Val missense_variant 0.2
rpoB 760369 p.Ser188Tyr missense_variant 0.29
rpoB 761082 p.Gly426Cys missense_variant 0.15
rpoB 761459 c.1653G>T synonymous_variant 0.33
rpoB 762199 p.Gly798Asp missense_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763649 p.His94Asn missense_variant 0.4
rpoC 764029 p.Glu220Asp missense_variant 0.15
rpoC 764875 c.1506C>T synonymous_variant 0.22
rpoC 766730 p.Val1121Met missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776293 p.Ala730Thr missense_variant 0.25
mmpL5 776339 c.2142C>T synonymous_variant 0.22
mmpL5 776496 p.Leu662Pro missense_variant 0.14
mmpL5 778392 p.Thr30Asn missense_variant 0.22
mmpR5 779399 p.Arg137Gln missense_variant 0.22
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800685 c.-124A>G upstream_gene_variant 0.25
rplC 801079 p.Ala91Ser missense_variant 0.29
rplC 801318 p.Met170Ile missense_variant 0.17
fbiC 1302885 c.-46G>A upstream_gene_variant 0.33
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
fbiC 1302937 p.Gln3Lys missense_variant 0.29
fbiC 1302956 p.Ser9Tyr missense_variant 0.33
fbiC 1303133 p.Ala68Glu missense_variant 0.29
fbiC 1303734 c.804C>T synonymous_variant 0.18
fbiC 1303738 p.Arg270Cys missense_variant 0.22
fbiC 1304519 p.Ala530Glu missense_variant 0.4
fbiC 1304565 c.1635C>A synonymous_variant 0.5
Rv1258c 1406099 c.1242C>A synonymous_variant 0.2
Rv1258c 1406415 p.Pro309Gln missense_variant 0.17
Rv1258c 1406484 p.Pro286His missense_variant 0.25
atpE 1460900 c.-145T>C upstream_gene_variant 0.12
atpE 1461191 c.147G>A synonymous_variant 0.29
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472063 n.218C>T non_coding_transcript_exon_variant 0.18
rrs 1472094 n.249T>A non_coding_transcript_exon_variant 0.25
rrs 1472102 n.257G>A non_coding_transcript_exon_variant 0.4
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.4
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.4
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.4
rrs 1472122 n.277G>A non_coding_transcript_exon_variant 0.45
rrs 1472127 n.282C>T non_coding_transcript_exon_variant 0.43
rrs 1472129 n.284G>C non_coding_transcript_exon_variant 0.43
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.45
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.46
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.54
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.54
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.42
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.27
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.15
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.15
rrs 1472222 n.377G>A non_coding_transcript_exon_variant 0.14
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.14
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.13
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.13
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.33
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.4
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.54
rrs 1472537 n.692C>T non_coding_transcript_exon_variant 0.54
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.3
rrs 1472543 n.699_700delCA non_coding_transcript_exon_variant 0.62
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.73
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.73
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.69
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.68
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.68
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.72
rrs 1472591 n.746G>A non_coding_transcript_exon_variant 0.76
rrs 1472598 n.753A>C non_coding_transcript_exon_variant 0.76
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.79
rrs 1472655 n.810G>A non_coding_transcript_exon_variant 0.8
rrs 1472658 n.813G>A non_coding_transcript_exon_variant 0.8
rrs 1472661 n.816A>G non_coding_transcript_exon_variant 0.8
rrs 1472665 n.820G>A non_coding_transcript_exon_variant 0.8
rrs 1472669 n.824_825insTAGA non_coding_transcript_exon_variant 0.82
rrs 1472678 n.833T>G non_coding_transcript_exon_variant 0.81
rrs 1472679 n.834T>C non_coding_transcript_exon_variant 0.78
rrs 1472682 n.839_843delGGGAT non_coding_transcript_exon_variant 0.81
rrs 1472689 n.844C>T non_coding_transcript_exon_variant 0.81
rrs 1472690 n.845C>A non_coding_transcript_exon_variant 0.82
rrs 1472695 n.850C>T non_coding_transcript_exon_variant 0.82
rrs 1472697 n.852T>A non_coding_transcript_exon_variant 0.8
rrs 1472700 n.855C>T non_coding_transcript_exon_variant 0.81
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.84
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.83
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.82
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.8
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.73
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.7
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.62
rrs 1472827 n.982G>T non_coding_transcript_exon_variant 0.58
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.58
rrs 1472836 n.991G>C non_coding_transcript_exon_variant 0.38
rrs 1472838 n.993A>T non_coding_transcript_exon_variant 0.38
rrs 1472840 n.995A>T non_coding_transcript_exon_variant 0.43
rrs 1472842 n.997G>A non_coding_transcript_exon_variant 0.39
rrs 1472844 n.999C>A non_coding_transcript_exon_variant 0.39
rrs 1472845 n.1000G>A non_coding_transcript_exon_variant 0.39
rrs 1472860 n.1015C>G non_coding_transcript_exon_variant 0.38
rrs 1472861 n.1016G>C non_coding_transcript_exon_variant 0.38
rrs 1472872 n.1027G>A non_coding_transcript_exon_variant 0.35
rrs 1472873 n.1028C>G non_coding_transcript_exon_variant 0.35
rrs 1472875 n.1030T>A non_coding_transcript_exon_variant 0.36
rrs 1472877 n.1032T>A non_coding_transcript_exon_variant 0.36
rrs 1472880 n.1035_1036insA non_coding_transcript_exon_variant 0.38
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.44
rrs 1472953 n.1108_1109insA non_coding_transcript_exon_variant 0.16
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.16
rrs 1472958 n.1114delT non_coding_transcript_exon_variant 0.16
rrs 1472967 n.1122G>T non_coding_transcript_exon_variant 0.18
rrs 1472969 n.1125_1126delCG non_coding_transcript_exon_variant 0.18
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.18
rrs 1472975 n.1130T>A non_coding_transcript_exon_variant 0.18
rrs 1472977 n.1132G>T non_coding_transcript_exon_variant 0.19
rrs 1472982 n.1137G>C non_coding_transcript_exon_variant 0.2
rrs 1473002 n.1157G>T non_coding_transcript_exon_variant 0.24
rrs 1473004 n.1159T>A non_coding_transcript_exon_variant 0.24
rrs 1473008 n.1163C>A non_coding_transcript_exon_variant 0.24
rrs 1473009 n.1164T>C non_coding_transcript_exon_variant 0.24
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.5
rrs 1473053 n.1208T>A non_coding_transcript_exon_variant 0.58
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.58
rrs 1473062 n.1217T>A non_coding_transcript_exon_variant 0.58
rrs 1473068 n.1223A>G non_coding_transcript_exon_variant 0.61
rrs 1473080 n.1235C>A non_coding_transcript_exon_variant 0.65
rrs 1473091 n.1246G>A non_coding_transcript_exon_variant 0.72
rrs 1473097 n.1252G>A non_coding_transcript_exon_variant 0.64
rrs 1473099 n.1254T>G non_coding_transcript_exon_variant 0.64
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.75
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.9
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.9
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.9
rrs 1473126 n.1282delG non_coding_transcript_exon_variant 0.82
rrs 1473131 n.1286G>T non_coding_transcript_exon_variant 0.82
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.82
rrs 1473147 n.1302G>T non_coding_transcript_exon_variant 0.82
rrs 1473148 n.1303G>A non_coding_transcript_exon_variant 0.82
rrs 1473150 n.1305T>G non_coding_transcript_exon_variant 0.82
rrs 1473161 n.1316A>C non_coding_transcript_exon_variant 0.82
rrs 1473163 n.1318C>T non_coding_transcript_exon_variant 0.82
rrs 1473164 n.1319C>A non_coding_transcript_exon_variant 0.82
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.82
rrs 1473172 n.1327T>C non_coding_transcript_exon_variant 0.82
rrs 1473173 n.1328C>T non_coding_transcript_exon_variant 0.82
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.82
rrs 1473192 n.1347A>G non_coding_transcript_exon_variant 0.69
rrs 1473205 n.1360T>C non_coding_transcript_exon_variant 0.69
rrl 1473480 n.-178C>A upstream_gene_variant 0.25
rrl 1474669 n.1012G>A non_coding_transcript_exon_variant 0.17
rrl 1474747 n.1090C>A non_coding_transcript_exon_variant 0.36
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.44
rrl 1474758 n.1101G>A non_coding_transcript_exon_variant 0.44
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.62
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.71
rrl 1474790 n.1133C>T non_coding_transcript_exon_variant 0.62
rrl 1474794 n.1137C>A non_coding_transcript_exon_variant 0.62
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.62
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.71
rrl 1474804 n.1147C>T non_coding_transcript_exon_variant 0.71
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.76
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.76
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.75
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.75
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.75
rrl 1474839 n.1182C>T non_coding_transcript_exon_variant 0.76
rrl 1474844 n.1187G>T non_coding_transcript_exon_variant 0.76
rrl 1474866 n.1209C>A non_coding_transcript_exon_variant 0.75
rrl 1474869 n.1212G>T non_coding_transcript_exon_variant 0.76
rrl 1474892 n.1235G>A non_coding_transcript_exon_variant 0.55
rrl 1474896 n.1239A>G non_coding_transcript_exon_variant 0.55
rrl 1474902 n.1245T>C non_coding_transcript_exon_variant 0.55
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.55
rrl 1474913 n.1256T>A non_coding_transcript_exon_variant 0.5
rrl 1474920 n.1263G>C non_coding_transcript_exon_variant 0.5
rrl 1475574 n.1917C>A non_coding_transcript_exon_variant 0.25
rrl 1475875 n.2218G>T non_coding_transcript_exon_variant 0.17
rrl 1476034 n.2377C>A non_coding_transcript_exon_variant 0.17
rrl 1476109 n.2452C>T non_coding_transcript_exon_variant 0.29
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 0.38
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 0.44
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.65
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.65
rrl 1476195 n.2538C>A non_coding_transcript_exon_variant 0.65
rrl 1476196 n.2539C>A non_coding_transcript_exon_variant 0.65
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.65
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.65
rrl 1476204 n.2547C>A non_coding_transcript_exon_variant 0.65
rrl 1476210 n.2553G>T non_coding_transcript_exon_variant 0.69
rrl 1476211 n.2554G>T non_coding_transcript_exon_variant 0.69
rrl 1476212 n.2555T>C non_coding_transcript_exon_variant 0.69
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.69
rrl 1476215 n.2558C>A non_coding_transcript_exon_variant 0.73
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.81
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.81
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.86
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.94
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.94
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.94
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 0.88
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 0.88
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 0.88
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 0.88
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.88
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 0.88
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 0.88
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.88
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.88
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.88
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.91
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.86
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.86
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.87
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.88
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.88
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.9
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.91
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.91
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.91
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.95
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.94
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.87
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.85
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.85
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.85
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.85
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.85
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.85
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.85
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.85
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.85
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.85
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.88
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.88
rrl 1476573 n.2916A>C non_coding_transcript_exon_variant 0.95
rrl 1476577 n.2920T>G non_coding_transcript_exon_variant 0.95
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.83
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.67
rrl 1476596 n.2939C>T non_coding_transcript_exon_variant 0.6
rrl 1476601 n.2944G>A non_coding_transcript_exon_variant 0.5
fabG1 1673960 p.Ala174Glu missense_variant 0.18
fabG1 1674040 p.Gly201Trp missense_variant 0.2
fabG1 1674043 p.Ala202Thr missense_variant 0.2
fabG1 1674053 p.Phe205Ser missense_variant 0.2
inhA 1674284 p.Val28Glu missense_variant 0.2
inhA 1674403 c.203delA frameshift_variant 0.18
inhA 1674424 p.Ala75Ser missense_variant 0.2
inhA 1674447 c.250delG frameshift_variant 0.25
inhA 1674863 p.Gly221Asp missense_variant 0.5
rpsA 1833559 c.18C>A synonymous_variant 0.29
rpsA 1834935 p.Ala465Val missense_variant 0.29
tlyA 1917771 c.-169G>T upstream_gene_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918150 p.Val71Phe missense_variant 0.33
ndh 2101803 p.Leu414Met missense_variant 0.22
ndh 2102045 p.Ala333Glu missense_variant 0.5
ndh 2102081 p.Gly321Asp missense_variant 0.67
ndh 2102107 c.936C>A synonymous_variant 0.4
ndh 2102139 c.904C>A synonymous_variant 0.25
ndh 2102193 p.Arg284Trp missense_variant 1.0
ndh 2102308 c.735G>T synonymous_variant 0.4
ndh 2103173 c.-132delG upstream_gene_variant 1.0
katG 2154457 p.Ile552Thr missense_variant 0.22
katG 2154540 c.1572C>A synonymous_variant 0.15
katG 2154596 p.Glu506* stop_gained 0.2
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155275 c.837C>A synonymous_variant 0.67
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156025 c.87C>A synonymous_variant 1.0
katG 2156201 c.-90G>T upstream_gene_variant 0.18
katG 2156481 c.-370G>T upstream_gene_variant 0.25
katG 2156565 c.-454C>T upstream_gene_variant 0.4
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168011 p.Ser868Arg missense_variant 1.0
PPE35 2168319 p.Thr765Ile missense_variant 1.0
PPE35 2168814 c.1798dupA frameshift_variant 1.0
PPE35 2170113 p.Ala167Glu missense_variant 0.25
PPE35 2170595 p.Leu6Phe missense_variant 0.25
Rv1979c 2222034 c.1131G>T synonymous_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2288900 c.342G>T synonymous_variant 0.29
pncA 2289294 c.-53G>T upstream_gene_variant 0.2
pncA 2289330 c.-89G>T upstream_gene_variant 0.17
pncA 2289651 c.-410T>C upstream_gene_variant 0.22
kasA 2518038 c.-77G>T upstream_gene_variant 0.2
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2518147 c.33C>T synonymous_variant 0.22
kasA 2519161 c.1047G>A synonymous_variant 1.0
eis 2714829 c.504C>A synonymous_variant 0.15
eis 2715029 p.Ala102Ser missense_variant 0.17
eis 2715113 p.Glu74Lys missense_variant 0.4
eis 2715125 p.Thr70Ala missense_variant 1.0
folC 2746825 c.774G>T synonymous_variant 0.29
folC 2746879 p.Lys240Asn missense_variant 0.33
folC 2747440 p.Leu53Phe missense_variant 0.5
folC 2747658 c.-60C>T upstream_gene_variant 0.25
folC 2747749 c.-151C>A upstream_gene_variant 0.18
pepQ 2859605 p.Gly272Trp missense_variant 0.29
pepQ 2859924 c.495G>A synonymous_variant 0.67
pepQ 2860605 c.-187C>A upstream_gene_variant 0.2
ribD 2986891 c.54delC frameshift_variant 0.22
ribD 2986994 c.156C>A synonymous_variant 0.33
ribD 2987332 p.Cys165Phe missense_variant 0.5
Rv2752c 3065101 p.Thr364Ser missense_variant 0.25
Rv2752c 3065982 c.210G>A synonymous_variant 0.33
thyX 3067787 p.Lys53Asn missense_variant 0.22
thyA 3074188 p.Gly95Val missense_variant 0.33
ald 3086693 c.-127G>T upstream_gene_variant 0.15
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086777 c.-43A>G upstream_gene_variant 0.15
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
ald 3087382 p.Asn188Ser missense_variant 0.22
ald 3087653 c.834A>G synonymous_variant 0.4
fbiD 3339093 c.-25G>A upstream_gene_variant 0.5
fbiD 3339273 c.156T>G synonymous_variant 0.4
Rv3083 3448589 p.Asp29Val missense_variant 0.67
Rv3083 3448783 p.Val94Ile missense_variant 1.0
Rv3083 3449195 p.Gly231Val missense_variant 0.29
Rv3083 3449840 p.Arg446Leu missense_variant 0.14
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474002 c.-5C>A upstream_gene_variant 0.18
fprA 3474036 c.30C>A synonymous_variant 0.18
fprA 3474038 p.Ser11Phe missense_variant 0.18
fprA 3474427 p.Val141Ile missense_variant 1.0
fprA 3475078 p.Gly358Arg missense_variant 0.33
fprA 3475159 p.Asn385Asp missense_variant 1.0
fprA 3475251 c.1245G>A synonymous_variant 0.2
fprA 3475329 c.1323G>T synonymous_variant 0.25
Rv3236c 3613181 c.-65C>A upstream_gene_variant 0.17
fbiA 3640421 c.-122C>A upstream_gene_variant 0.17
fbiB 3640998 c.-537C>A upstream_gene_variant 0.2
fbiB 3641160 c.-375C>T upstream_gene_variant 0.25
fbiA 3641222 p.Pro227His missense_variant 0.29
fbiB 3641304 c.-231C>A upstream_gene_variant 0.29
fbiA 3641406 p.Trp288Cys missense_variant 0.22
fbiB 3641609 c.75C>T synonymous_variant 0.2
fbiB 3642287 c.753G>T synonymous_variant 0.67
fbiB 3642681 p.Ala383Ser missense_variant 0.5
alr 3841226 c.195C>A synonymous_variant 0.5
alr 3841366 p.Gly19Ser missense_variant 0.25
alr 3841437 c.-17G>T upstream_gene_variant 0.2
rpoA 3878058 c.450G>A synonymous_variant 0.22
ddn 3987033 p.Leu64Ile missense_variant 0.4
clpC1 4038403 c.2302T>C synonymous_variant 1.0
clpC1 4038408 p.Pro766Gln missense_variant 0.22
clpC1 4038474 p.Ser744Ile missense_variant 0.25
clpC1 4038479 c.2226C>A synonymous_variant 0.25
clpC1 4038560 c.2145C>T synonymous_variant 0.29
clpC1 4040173 p.Leu178Ile missense_variant 0.17
clpC1 4040557 p.Glu50* stop_gained 0.15
panD 4043927 p.His119Asn missense_variant 0.4
embC 4239704 c.-159C>A upstream_gene_variant 0.18
embC 4239726 c.-137G>T upstream_gene_variant 0.17
embC 4239761 c.-102C>T upstream_gene_variant 0.18
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242970 c.-263C>T upstream_gene_variant 1.0
embA 4243746 p.Gly172Ser missense_variant 0.67
embA 4244220 c.988C>T synonymous_variant 1.0
embA 4244944 p.Ala571Asp missense_variant 0.67
embB 4246551 p.Asn13Ser missense_variant 1.0
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247277 p.Pro255Gln missense_variant 0.17
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4248564 p.Ala684Asp missense_variant 0.33
aftB 4267337 c.1500C>T synonymous_variant 0.25
aftB 4267427 c.1410G>C synonymous_variant 0.25
aftB 4267438 p.Arg467Trp missense_variant 0.25
aftB 4267815 p.Ala341Glu missense_variant 0.33
aftB 4267858 p.Ile327Val missense_variant 1.0
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
ethA 4326632 p.His281Leu missense_variant 0.25
ethA 4327178 p.Arg99Pro missense_variant 0.25
ethR 4328194 p.Arg216Cys missense_variant 0.2
ethA 4328261 c.-788C>A upstream_gene_variant 0.2
ethA 4328314 c.-841G>T upstream_gene_variant 0.2
whiB6 4338276 c.246C>A synonymous_variant 0.5
whiB6 4338528 c.-7A>G upstream_gene_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4408127 c.76T>C synonymous_variant 0.22