TB-Profiler result

Run: ERR6198317
Summary

Run ID: ERR6198317

Sample name:

Date: 02-04-2023 01:50:50

Number of reads: 1385489

Percentage reads mapped: 84.96

Strain: La1.2

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
La1 M.bovis None None 0.99
La1.2 M.bovis None None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
pncA 2289073 p.His57Asp missense_variant 1.0 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5752 c.513G>A synonymous_variant 1.0
gyrB 6214 c.975G>C synonymous_variant 0.14
gyrB 6238 c.999G>A synonymous_variant 0.16
gyrB 6242 c.1003_1005delCGCinsAGG synonymous_variant 0.16
gyrB 6259 p.Asp340Glu missense_variant 0.14
gyrA 6406 c.-896C>T upstream_gene_variant 1.0
gyrB 6446 p.Ala403Ser missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 0.98
gyrA 7601 c.300C>G synonymous_variant 0.15
gyrA 7619 c.318C>G synonymous_variant 0.15
gyrA 7622 c.321C>T synonymous_variant 0.15
gyrA 7628 c.327G>C synonymous_variant 0.14
gyrA 7631 c.330G>C synonymous_variant 0.14
gyrA 7652 c.351C>T synonymous_variant 0.14
gyrA 7658 c.357A>C synonymous_variant 0.15
gyrA 7763 c.462T>G synonymous_variant 0.18
gyrA 7770 p.Asp157His missense_variant 0.19
gyrA 7821 c.520C>T synonymous_variant 0.95
gyrA 8285 c.984C>T synonymous_variant 1.0
gyrA 8516 c.1215T>C synonymous_variant 0.15
gyrA 8519 c.1218A>G synonymous_variant 0.16
gyrA 8537 c.1236G>A synonymous_variant 0.14
gyrA 8540 c.1239C>G synonymous_variant 0.15
gyrA 8561 c.1260A>G synonymous_variant 0.19
gyrA 8571 c.1270C>T synonymous_variant 0.21
gyrA 8603 c.1302A>G synonymous_variant 0.24
gyrA 8619 c.1318T>C synonymous_variant 0.28
gyrA 8624 c.1323G>C synonymous_variant 0.27
gyrA 8636 c.1335A>C synonymous_variant 0.32
gyrA 8642 c.1341A>G synonymous_variant 0.3
gyrA 8672 c.1371A>G synonymous_variant 0.3
gyrA 8693 c.1392T>C synonymous_variant 0.32
gyrA 8705 c.1404C>T synonymous_variant 0.26
gyrA 8706 c.1405C>T synonymous_variant 0.18
gyrA 8711 c.1410A>C synonymous_variant 0.18
gyrA 8714 c.1413A>G synonymous_variant 0.18
gyrA 8723 c.1422G>C synonymous_variant 0.18
gyrA 8741 c.1440C>T synonymous_variant 0.95
gyrA 9119 c.1818A>G synonymous_variant 0.15
gyrA 9137 c.1836C>T synonymous_variant 0.16
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9146 c.1845C>T synonymous_variant 0.16
gyrA 9153 p.Thr618Glu missense_variant 0.15
gyrA 9164 c.1863G>A synonymous_variant 0.15
gyrA 9182 c.1881T>C synonymous_variant 0.14
gyrA 9191 c.1890G>C synonymous_variant 0.14
gyrA 9197 c.1896G>C synonymous_variant 0.16
gyrA 9200 c.1899A>G synonymous_variant 0.16
gyrA 9204 p.Ser635Thr missense_variant 0.17
gyrA 9276 c.1975C>T synonymous_variant 0.14
gyrA 9284 c.1983T>C synonymous_variant 0.17
gyrA 9296 c.1995T>C synonymous_variant 0.15
gyrA 9300 p.Ala667Ser missense_variant 0.17
gyrA 9304 p.Gly668Glu missense_variant 1.0
gyrA 9323 c.2022C>G synonymous_variant 0.17
gyrA 9335 c.2034G>C synonymous_variant 0.16
gyrA 9345 c.2044A>C synonymous_variant 0.16
gyrA 9377 c.2076A>G synonymous_variant 0.19
gyrA 9383 c.2082T>A synonymous_variant 0.18
gyrA 9386 c.2085T>C synonymous_variant 0.18
gyrA 9395 c.2094G>C synonymous_variant 0.19
gyrA 9398 c.2097T>C synonymous_variant 0.18
gyrA 9666 p.Arg789Cys missense_variant 0.14
fgd1 491091 c.309T>G synonymous_variant 0.15
fgd1 491097 c.315G>C synonymous_variant 0.14
fgd1 491106 c.324T>A synonymous_variant 0.17
fgd1 491113 c.331C>T synonymous_variant 0.22
fgd1 491121 c.339A>G synonymous_variant 0.22
fgd1 491133 c.351A>C synonymous_variant 0.27
fgd1 491144 p.Ala121Asp missense_variant 0.29
fgd1 491166 c.384G>C synonymous_variant 0.26
fgd1 491178 c.396G>A synonymous_variant 0.22
fgd1 491181 c.399T>C synonymous_variant 0.22
fgd1 491191 p.Gly137Arg missense_variant 0.21
fgd1 491194 c.412_414delCTAinsTTG synonymous_variant 0.2
fgd1 491203 p.Gln141Glu missense_variant 0.19
fgd1 491206 c.424C>T synonymous_variant 0.19
fgd1 491212 p.Ser144Arg missense_variant 0.18
fgd1 491232 c.450T>C synonymous_variant 0.26
fgd1 491241 p.Asp153Glu missense_variant 0.26
fgd1 491244 c.462T>C synonymous_variant 0.26
fgd1 491250 c.468G>C synonymous_variant 0.26
fgd1 491259 c.477T>C synonymous_variant 0.27
fgd1 491313 c.531C>G synonymous_variant 0.22
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 576616 c.1269G>C synonymous_variant 0.22
ccsA 619709 c.-182T>G upstream_gene_variant 0.19
ccsA 620412 c.522T>C synonymous_variant 0.15
ccsA 620415 c.525T>C synonymous_variant 0.15
ccsA 620433 c.543C>G synonymous_variant 0.18
ccsA 620436 c.546T>C synonymous_variant 0.19
ccsA 620439 c.549T>C synonymous_variant 0.18
ccsA 620748 c.858T>C synonymous_variant 0.15
ccsA 620760 c.870C>G synonymous_variant 0.14
ccsA 620766 c.876C>G synonymous_variant 0.14
rpoB 760118 c.312T>C synonymous_variant 0.14
rpoB 760130 p.Asp108Glu missense_variant 0.15
rpoB 760139 c.333A>G synonymous_variant 0.14
rpoB 760142 c.336C>G synonymous_variant 0.15
rpoB 760751 c.945G>C synonymous_variant 0.14
rpoB 760763 c.957C>T synonymous_variant 0.16
rpoB 760769 c.963C>G synonymous_variant 0.16
rpoB 760793 c.987A>G synonymous_variant 0.21
rpoB 760805 c.999G>C synonymous_variant 0.28
rpoB 760817 c.1011A>G synonymous_variant 0.17
rpoB 760820 c.1014T>C synonymous_variant 0.17
rpoB 760826 c.1020C>T synonymous_variant 0.21
rpoB 760830 c.1024T>C synonymous_variant 0.32
rpoB 760841 c.1035T>C synonymous_variant 0.32
rpoB 760845 p.Thr347Ala missense_variant 0.33
rpoB 760859 c.1053T>C synonymous_variant 0.26
rpoB 760865 c.1059C>T synonymous_variant 0.26
rpoB 760869 p.Val355Ile missense_variant 0.21
rpoB 760913 c.1107C>T synonymous_variant 0.25
rpoB 760917 c.1111_1113delCGCinsAGG synonymous_variant 0.27
rpoB 760928 c.1122G>C synonymous_variant 0.3
rpoB 760938 c.1132C>T synonymous_variant 0.29
rpoB 760946 c.1140A>G synonymous_variant 0.24
rpoB 760970 c.1164G>C synonymous_variant 0.21
rpoB 760985 c.1179G>C synonymous_variant 0.16
rpoB 760991 c.1185G>C synonymous_variant 0.15
rpoB 761006 c.1200C>G synonymous_variant 0.16
rpoB 761015 c.1209G>C synonymous_variant 0.19
rpoB 761027 c.1221A>G synonymous_variant 0.18
rpoB 761037 c.1231T>C synonymous_variant 0.2
rpoB 761150 c.1344A>G synonymous_variant 0.17
rpoB 761612 c.1806G>C synonymous_variant 0.14
rpoB 761615 c.1809A>C synonymous_variant 0.16
rpoB 762176 c.2370T>C synonymous_variant 0.17
rpoB 762233 c.2427G>C synonymous_variant 0.14
rpoB 762254 c.2448T>G synonymous_variant 0.17
rpoB 762257 c.2451C>G synonymous_variant 0.16
rpoB 762284 c.2478G>C synonymous_variant 0.17
rpoB 762317 c.2511A>G synonymous_variant 0.17
rpoB 762329 c.2523G>C synonymous_variant 0.15
rpoB 762362 p.Glu852Asp missense_variant 0.15
rpoB 762369 c.2563T>C synonymous_variant 0.16
rpoC 762803 c.-567C>T upstream_gene_variant 0.92
rpoC 762827 c.-543G>C upstream_gene_variant 0.15
rpoC 762836 c.-534C>T upstream_gene_variant 0.25
rpoC 762857 c.-513C>G upstream_gene_variant 0.26
rpoC 762863 c.-507T>G upstream_gene_variant 0.3
rpoB 762868 p.Tyr1021Phe missense_variant 0.26
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763070 c.-300T>C upstream_gene_variant 0.14
rpoC 763085 c.-285C>G upstream_gene_variant 0.15
rpoC 763570 c.201G>C synonymous_variant 0.15
rpoC 763573 c.204G>C synonymous_variant 0.16
rpoC 763900 c.531G>C synonymous_variant 0.17
rpoC 763945 c.576T>C synonymous_variant 0.29
rpoC 763948 c.579G>C synonymous_variant 0.3
rpoC 763951 c.582G>C synonymous_variant 0.3
rpoC 763960 c.591T>G synonymous_variant 0.29
rpoC 763969 c.600C>T synonymous_variant 0.3
rpoC 763978 c.609C>G synonymous_variant 0.28
rpoC 763991 p.Ile208Leu missense_variant 0.24
rpoC 764002 c.633C>G synonymous_variant 0.31
rpoC 764005 c.636G>C synonymous_variant 0.3
rpoC 764024 c.655T>C synonymous_variant 0.3
rpoC 764044 c.675T>C synonymous_variant 0.26
rpoC 764059 c.690G>C synonymous_variant 0.24
rpoC 764116 c.747C>T synonymous_variant 0.19
rpoC 764119 c.750G>A synonymous_variant 0.19
rpoC 764161 c.792G>C synonymous_variant 0.15
rpoC 764278 c.909A>G synonymous_variant 0.14
rpoC 764317 c.948C>G synonymous_variant 0.29
rpoC 764320 c.951C>G synonymous_variant 0.29
rpoC 764326 c.957G>C synonymous_variant 0.31
rpoC 764344 c.975C>T synonymous_variant 0.33
rpoC 764365 c.996C>T synonymous_variant 0.31
rpoC 764387 c.1018T>C synonymous_variant 0.19
rpoC 764392 c.1023C>T synonymous_variant 0.14
rpoC 764405 c.1036_1038delAGGinsCGC synonymous_variant 0.21
rpoC 764410 c.1041G>C synonymous_variant 0.16
rpoC 764428 c.1059G>C synonymous_variant 0.19
rpoC 764431 c.1062G>C synonymous_variant 0.16
rpoC 764434 c.1065A>G synonymous_variant 0.16
rpoC 764446 c.1077T>C synonymous_variant 0.15
rpoC 764458 c.1089G>C synonymous_variant 0.14
rpoC 764497 c.1128A>G synonymous_variant 0.14
rpoC 764500 c.1131C>G synonymous_variant 0.16
rpoC 764503 c.1134G>C synonymous_variant 0.17
rpoC 764521 c.1152T>C synonymous_variant 0.27
rpoC 764524 c.1155C>A synonymous_variant 0.27
rpoC 764536 c.1167G>C synonymous_variant 0.22
rpoC 764539 c.1170C>G synonymous_variant 0.29
rpoC 764566 c.1197C>G synonymous_variant 0.28
rpoC 764575 c.1206T>G synonymous_variant 0.21
rpoC 764576 c.1207_1208delTCinsAG synonymous_variant 0.21
rpoC 764593 c.1224C>T synonymous_variant 0.24
rpoC 764611 c.1242G>C synonymous_variant 0.23
rpoC 764626 c.1257C>T synonymous_variant 0.23
rpoC 764911 c.1542A>G synonymous_variant 0.18
rpoC 764932 c.1563C>G synonymous_variant 0.2
rpoC 764948 c.1579T>C synonymous_variant 0.17
rpoC 764968 c.1599T>C synonymous_variant 0.17
rpoC 764995 c.1626C>G synonymous_variant 0.19
rpoC 765007 c.1638T>G synonymous_variant 0.16
rpoC 765008 c.1639T>C synonymous_variant 0.17
rpoC 765016 c.1647C>G synonymous_variant 0.15
rpoC 765019 c.1650A>G synonymous_variant 0.15
rpoC 765352 c.1983G>C synonymous_variant 0.14
rpoC 765383 p.Met672Leu missense_variant 0.21
rpoC 765398 c.2029C>T synonymous_variant 0.23
rpoC 765404 p.Leu679Val missense_variant 0.21
rpoC 765409 c.2040T>C synonymous_variant 0.2
rpoC 765412 c.2043T>C synonymous_variant 0.23
rpoC 765421 c.2052C>G synonymous_variant 0.24
rpoC 765451 c.2082C>T synonymous_variant 0.29
rpoC 765469 c.2100G>C synonymous_variant 0.25
rpoC 765478 c.2109T>C synonymous_variant 0.28
rpoC 765499 c.2130C>G synonymous_variant 0.24
rpoC 765508 c.2139C>G synonymous_variant 0.25
rpoC 765517 c.2148C>G synonymous_variant 0.24
rpoC 765529 c.2160C>T synonymous_variant 0.24
rpoC 765541 c.2172C>G synonymous_variant 0.17
rpoC 765553 c.2184C>T synonymous_variant 0.22
rpoC 765556 c.2187G>C synonymous_variant 0.24
rpoC 765562 c.2193G>C synonymous_variant 0.24
rpoC 765578 c.2209C>T synonymous_variant 0.24
rpoC 765589 c.2220G>C synonymous_variant 0.23
rpoC 765613 p.His748Gln missense_variant 0.18
rpoC 765625 c.2256C>G synonymous_variant 0.16
rpoC 765628 c.2259G>C synonymous_variant 0.17
rpoC 765631 p.Asp754Glu missense_variant 0.19
rpoC 765688 c.2319G>A synonymous_variant 0.14
rpoC 766363 c.2994G>C synonymous_variant 0.14
rpoC 766426 c.3057C>T synonymous_variant 0.15
rpoC 766774 c.3405T>C synonymous_variant 0.21
rpoC 766795 c.3426C>T synonymous_variant 0.23
rpoC 766804 c.3435A>G synonymous_variant 0.27
rpoC 766843 c.3474T>C synonymous_variant 0.35
rpoC 766861 c.3492G>T synonymous_variant 0.37
rpoC 766864 c.3495G>C synonymous_variant 0.33
rpoC 766883 p.Ser1172Ala missense_variant 0.39
rpoC 766894 c.3525T>C synonymous_variant 0.38
rpoC 766895 c.3526T>C synonymous_variant 0.38
rpoC 766900 c.3531T>C synonymous_variant 0.36
rpoC 766903 c.3534C>T synonymous_variant 0.38
rpoC 766918 c.3549C>T synonymous_variant 0.43
rpoC 766933 c.3564A>G synonymous_variant 0.38
rpoC 766963 c.3594T>C synonymous_variant 0.35
rpoC 766972 c.3603G>C synonymous_variant 0.25
rpoC 766996 c.3627C>T synonymous_variant 0.18
rpoC 767023 c.3654C>T synonymous_variant 0.26
rpoC 767032 c.3663G>C synonymous_variant 0.29
rpoC 767059 c.3690T>G synonymous_variant 0.18
rpoC 767062 c.3693C>A synonymous_variant 0.17
rpoC 767065 c.3696G>C synonymous_variant 0.17
rpoC 767095 c.3726C>T synonymous_variant 0.17
rpoC 767098 c.3729T>C synonymous_variant 0.16
rpoC 767119 c.3750A>G synonymous_variant 0.16
rpoC 767134 c.3765C>A synonymous_variant 0.15
rpoC 767191 c.3822C>G synonymous_variant 0.15
rpoC 767206 c.3837C>G synonymous_variant 0.18
rpoC 767209 c.3840T>C synonymous_variant 0.15
rpoC 767212 c.3843G>C synonymous_variant 0.18
rpoC 767221 c.3852C>G synonymous_variant 0.16
rpoC 767230 c.3861G>C synonymous_variant 0.17
rpoC 767233 c.3864T>C synonymous_variant 0.18
rpoC 767263 c.3894T>C synonymous_variant 0.14
rpoC 767264 p.Ala1299Gln missense_variant 0.14
rpoC 767302 c.3933C>G synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781595 c.36T>C synonymous_variant 0.14
rpsL 781664 c.105C>T synonymous_variant 0.18
rpsL 781682 c.123T>C synonymous_variant 0.15
rpsL 781718 c.159C>G synonymous_variant 0.19
rpsL 781728 c.169T>C synonymous_variant 0.15
rpsL 781736 c.177T>C synonymous_variant 0.15
rpsL 781808 c.249C>T synonymous_variant 0.16
fbiC 1302899 c.-32A>G upstream_gene_variant 1.0
fbiC 1303671 c.741C>T synonymous_variant 0.14
fbiC 1303674 c.744C>G synonymous_variant 0.22
fbiC 1303681 c.751T>C synonymous_variant 0.21
fbiC 1303689 c.759T>C synonymous_variant 0.22
fbiC 1303695 c.765T>C synonymous_variant 0.2
fbiC 1303704 c.774T>C synonymous_variant 0.25
fbiC 1303705 p.Leu259Met missense_variant 0.25
fbiC 1303708 c.778T>C synonymous_variant 0.25
fbiC 1303731 c.801A>G synonymous_variant 0.23
fbiC 1303732 p.Ser268Thr missense_variant 0.23
fbiC 1303737 c.807G>A synonymous_variant 0.21
fbiC 1303740 c.810C>T synonymous_variant 0.22
fbiC 1303746 p.Asp272Glu missense_variant 0.18
fbiC 1303749 c.819G>C synonymous_variant 0.17
fbiC 1303752 c.822A>G synonymous_variant 0.19
fbiC 1303755 c.825T>C synonymous_variant 0.19
fbiC 1303788 c.858T>C synonymous_variant 0.17
fbiC 1303789 p.Ile287Val missense_variant 0.16
fbiC 1303846 p.Phe306Val missense_variant 0.27
fbiC 1303854 c.924T>C synonymous_variant 0.28
fbiC 1303857 c.927C>G synonymous_variant 0.28
fbiC 1303860 c.930A>G synonymous_variant 0.27
fbiC 1303866 p.Glu312Asp missense_variant 0.26
fbiC 1303869 c.939T>C synonymous_variant 0.26
fbiC 1303875 c.945G>C synonymous_variant 0.25
fbiC 1303878 c.948G>A synonymous_variant 0.25
fbiC 1303884 c.954T>G synonymous_variant 0.25
fbiC 1303890 c.960G>C synonymous_variant 0.25
fbiC 1303893 c.963G>C synonymous_variant 0.27
fbiC 1303905 c.975G>C synonymous_variant 0.26
fbiC 1303911 c.981G>C synonymous_variant 0.27
fbiC 1303935 c.1005G>C synonymous_variant 0.28
fbiC 1303947 c.1017T>C synonymous_variant 0.25
fbiC 1303948 p.Gly340Arg missense_variant 0.24
fbiC 1303956 c.1026A>G synonymous_variant 0.23
fbiC 1303961 p.Arg344Leu missense_variant 0.25
fbiC 1303971 c.1041T>C synonymous_variant 0.23
fbiC 1303998 c.1068T>C synonymous_variant 0.15
fbiC 1304007 c.1077G>T synonymous_variant 0.14
fbiC 1304019 c.1089C>T synonymous_variant 0.19
fbiC 1304022 c.1092T>C synonymous_variant 0.17
fbiC 1304040 c.1110C>G synonymous_variant 0.19
fbiC 1304856 c.1926C>G synonymous_variant 0.15
fbiC 1304893 p.Gly655Ser missense_variant 0.19
fbiC 1304916 c.1986T>C synonymous_variant 0.15
fbiC 1304919 c.1989C>G synonymous_variant 0.22
fbiC 1304928 c.1998T>C synonymous_variant 0.17
fbiC 1304931 c.2001C>G synonymous_variant 0.22
fbiC 1304934 c.2004C>A synonymous_variant 0.17
fbiC 1304937 c.2007G>C synonymous_variant 0.17
fbiC 1304940 c.2010A>G synonymous_variant 0.16
fbiC 1304952 c.2022C>T synonymous_variant 0.15
fbiC 1304955 c.2025G>A synonymous_variant 0.17
fbiC 1304958 c.2028T>G synonymous_variant 0.15
fbiC 1304991 c.2061G>C synonymous_variant 0.21
fbiC 1304994 c.2064A>G synonymous_variant 0.17
fbiC 1304995 p.Leu689Glu missense_variant 0.17
fbiC 1305006 p.Glu692Asp missense_variant 0.19
fbiC 1305015 c.2085G>C synonymous_variant 0.17
fbiC 1305021 c.2091C>G synonymous_variant 0.15
fbiC 1305033 c.2103T>C synonymous_variant 0.14
Rv1258c 1406663 c.678C>T synonymous_variant 1.0
atpE 1460855 c.-190T>C upstream_gene_variant 0.13
atpE 1461185 c.141G>C synonymous_variant 0.16
atpE 1461197 c.153A>G synonymous_variant 0.16
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 0.15
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.17
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.17
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.17
rrs 1471969 n.124T>C non_coding_transcript_exon_variant 0.24
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.24
rrs 1472030 n.185G>T non_coding_transcript_exon_variant 0.23
rrs 1472031 n.186G>T non_coding_transcript_exon_variant 0.23
rrs 1472033 n.188A>G non_coding_transcript_exon_variant 0.24
rrs 1472034 n.189T>C non_coding_transcript_exon_variant 0.24
rrs 1472040 n.195T>C non_coding_transcript_exon_variant 0.24
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 0.2
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 0.19
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 0.23
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.18
rrl 1473752 n.95G>T non_coding_transcript_exon_variant 0.22
rrl 1473756 n.99G>T non_coding_transcript_exon_variant 0.23
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.23
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.31
rrl 1473813 n.156C>T non_coding_transcript_exon_variant 0.24
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.42
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.32
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.35
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.35
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.25
rrl 1473974 n.317T>A non_coding_transcript_exon_variant 0.23
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.17
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.17
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.16
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.16
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.15
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.14
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.15
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.18
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.18
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.17
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.17
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.16
rrl 1474952 n.1296_1300delCATCC non_coding_transcript_exon_variant 0.18
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.18
rrl 1474962 n.1305T>C non_coding_transcript_exon_variant 0.19
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.19
rrl 1474964 n.1307T>A non_coding_transcript_exon_variant 0.19
rrl 1474967 n.1311_1315delGGGTG non_coding_transcript_exon_variant 0.23
rrl 1474991 n.1334T>C non_coding_transcript_exon_variant 0.29
rrl 1474995 n.1338T>G non_coding_transcript_exon_variant 0.31
rrl 1475005 n.1348C>T non_coding_transcript_exon_variant 0.36
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.38
rrl 1475027 n.1370G>T non_coding_transcript_exon_variant 0.36
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 0.36
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.24
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.28
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.17
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.19
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.16
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.22
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.24
rrl 1475436 n.1779C>T non_coding_transcript_exon_variant 0.23
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.2
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.25
rrl 1475619 n.1962C>T non_coding_transcript_exon_variant 0.24
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.23
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.23
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.23
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.22
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.18
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.17
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.27
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.19
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.21
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.23
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.23
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.22
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.24
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.24
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.17
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.17
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.27
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.27
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.33
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.3
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.3
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.31
rrl 1476716 n.3059A>C non_coding_transcript_exon_variant 0.26
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.29
rrl 1476726 n.3069A>G non_coding_transcript_exon_variant 0.25
rrl 1476732 n.3075T>C non_coding_transcript_exon_variant 0.16
rrl 1476746 n.3089T>C non_coding_transcript_exon_variant 0.17
fabG1 1673553 p.Asp38Glu missense_variant 0.21
inhA 1674486 c.285T>C synonymous_variant 0.18
inhA 1674489 c.288G>C synonymous_variant 0.16
inhA 1674542 p.Ala114Glu missense_variant 0.19
inhA 1674549 c.348G>C synonymous_variant 0.2
inhA 1674624 c.423A>T synonymous_variant 0.25
inhA 1674627 c.426T>G synonymous_variant 0.25
inhA 1674654 c.453G>C synonymous_variant 0.15
rpsA 1833422 c.-120G>T upstream_gene_variant 1.0
rpsA 1833610 c.69C>T synonymous_variant 0.17
rpsA 1833661 c.120A>G synonymous_variant 0.21
rpsA 1833664 c.123C>G synonymous_variant 0.21
rpsA 1833667 c.126C>G synonymous_variant 0.2
rpsA 1833721 c.180A>G synonymous_variant 0.17
rpsA 1833727 c.186G>C synonymous_variant 0.17
rpsA 1833742 c.201A>G synonymous_variant 0.24
rpsA 1833745 c.204G>C synonymous_variant 0.22
rpsA 1833760 c.219C>T synonymous_variant 0.2
rpsA 1833771 p.Asn77Ser missense_variant 0.18
rpsA 1833793 c.252C>T synonymous_variant 0.18
rpsA 1833808 c.267G>T synonymous_variant 0.17
rpsA 1833811 c.270G>T synonymous_variant 0.17
rpsA 1833838 c.297G>C synonymous_variant 0.17
rpsA 1833841 c.300C>G synonymous_variant 0.17
rpsA 1833847 c.306C>G synonymous_variant 0.21
rpsA 1833856 c.315A>G synonymous_variant 0.26
rpsA 1833874 c.333T>C synonymous_variant 0.2
rpsA 1833940 c.399C>G synonymous_variant 0.15
rpsA 1834859 p.Ala440Thr missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102106 p.Gly313Arg missense_variant 1.0
ndh 2103173 c.-132delG upstream_gene_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155503 c.609C>T synonymous_variant 1.0
katG 2156025 c.87C>A synonymous_variant 1.0
katG 2156465 c.-354C>T upstream_gene_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2168011 p.Ser868Arg missense_variant 1.0
PPE35 2168814 c.1798dupA frameshift_variant 1.0
PPE35 2170047 p.Leu189Pro missense_variant 0.2
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2518174 c.60A>G synonymous_variant 0.13
kasA 2518183 c.69G>A synonymous_variant 0.13
kasA 2518190 p.Ser26Ala missense_variant 0.16
kasA 2518220 c.106C>T synonymous_variant 0.18
kasA 2518248 p.Ala45Val missense_variant 0.17
pepQ 2860159 p.Ala87Gly missense_variant 0.4
Rv2752c 3064831 p.Ala454Ser missense_variant 0.15
Rv2752c 3064838 c.1354T>C synonymous_variant 0.19
Rv2752c 3064839 c.1353C>G synonymous_variant 0.19
Rv2752c 3064860 c.1332G>C synonymous_variant 0.16
Rv2752c 3065048 c.1144C>T synonymous_variant 0.19
Rv2752c 3065055 c.1137T>C synonymous_variant 0.23
Rv2752c 3065085 c.1105_1107delAGGinsCGC synonymous_variant 0.19
Rv2752c 3065088 c.1104A>C synonymous_variant 0.19
Rv2752c 3065097 c.1095C>T synonymous_variant 0.18
Rv2752c 3065100 c.1092C>G synonymous_variant 0.18
Rv2752c 3065109 c.1081_1083delAGAinsCGC synonymous_variant 0.15
Rv2752c 3065142 c.1050A>C synonymous_variant 0.14
Rv2752c 3065146 p.Phe349Tyr missense_variant 0.15
Rv2752c 3065183 p.Ser337Ala missense_variant 0.14
Rv2752c 3065268 c.924A>G synonymous_variant 0.18
Rv2752c 3065288 c.904T>C synonymous_variant 0.14
Rv2752c 3065295 p.Gln299Arg missense_variant 0.14
Rv2752c 3065298 p.Asp298Glu missense_variant 0.14
Rv2752c 3065306 p.Ala296Pro missense_variant 0.14
Rv2752c 3065311 p.Thr294Met missense_variant 0.14
Rv2752c 3065313 c.879A>G synonymous_variant 0.14
Rv2752c 3065323 p.Ala290Gly missense_variant 0.14
Rv2752c 3065334 p.Leu286Val missense_variant 0.13
Rv2752c 3065355 c.837A>G synonymous_variant 0.13
thyX 3067430 c.516C>G synonymous_variant 0.14
thyX 3067433 c.513C>G synonymous_variant 0.14
thyX 3067676 c.270C>G synonymous_variant 0.13
thyX 3067681 p.Cys89Arg missense_variant 0.17
thyX 3067691 c.255C>T synonymous_variant 0.17
thyX 3067694 c.252G>C synonymous_variant 0.15
thyX 3067721 c.225T>C synonymous_variant 0.15
thyX 3067781 c.165C>G synonymous_variant 0.2
thyX 3067786 p.Thr54Ala missense_variant 0.79
thyX 3067799 c.147G>A synonymous_variant 0.2
thyX 3067802 c.144C>G synonymous_variant 0.19
ald 3086728 c.-92C>T upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087084 c.266delA frameshift_variant 1.0
fbiD 3339154 p.Ile13Leu missense_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.8
Rv3083 3448745 p.Ile81Ser missense_variant 1.0
Rv3083 3448783 p.Val94Ile missense_variant 1.0
fprA 3473809 c.-198G>C upstream_gene_variant 0.19
fprA 3473812 c.-195G>A upstream_gene_variant 0.19
fprA 3473843 c.-164C>G upstream_gene_variant 0.17
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474427 p.Val141Ile missense_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
whiB7 3568425 c.255T>G synonymous_variant 0.2
rpoA 3877587 c.921A>G synonymous_variant 0.19
rpoA 3877613 p.Ile299Val missense_variant 0.21
rpoA 3878058 c.450G>C synonymous_variant 0.15
rpoA 3878070 c.438T>C synonymous_variant 0.14
rpoA 3878073 c.435C>T synonymous_variant 0.15
rpoA 3878103 c.405A>G synonymous_variant 0.16
rpoA 3878106 c.402G>C synonymous_variant 0.17
rpoA 3878118 c.390T>C synonymous_variant 0.14
rpoA 3878143 p.Gly122Asp missense_variant 0.16
rpoA 3878157 c.351C>G synonymous_variant 0.19
rpoA 3878163 c.345C>T synonymous_variant 0.16
rpoA 3878169 c.339G>C synonymous_variant 0.19
rpoA 3878175 c.333G>C synonymous_variant 0.15
rpoA 3878217 c.291A>G synonymous_variant 0.19
rpoA 3878364 c.144A>C synonymous_variant 0.17
rpoA 3878385 c.123C>G synonymous_variant 0.17
rpoA 3878388 c.120C>G synonymous_variant 0.17
rpoA 3878391 c.117T>C synonymous_variant 0.17
rpoA 3878394 c.114G>C synonymous_variant 0.17
rpoA 3878415 c.93C>T synonymous_variant 0.21
rpoA 3878424 c.84G>T synonymous_variant 0.2
rpoA 3878433 c.75G>C synonymous_variant 0.23
rpoA 3878436 c.72A>G synonymous_variant 0.24
rpoA 3878442 c.66G>C synonymous_variant 0.22
rpoA 3878451 c.57C>G synonymous_variant 0.17
rpoA 3878454 c.54A>C synonymous_variant 0.17
rpoA 3878458 p.Asn17Ser missense_variant 0.17
rpoA 3878472 p.Asp12Glu missense_variant 0.17
rpoA 3878478 c.30C>G synonymous_variant 0.18
rpoA 3878484 c.24C>A synonymous_variant 0.2
rpoA 3878630 c.-124delC upstream_gene_variant 1.0
clpC1 4038403 c.2302T>C synonymous_variant 1.0
clpC1 4038499 p.Ser736Gly missense_variant 0.15
clpC1 4038519 p.Arg729Gln missense_variant 0.15
clpC1 4038521 c.2184C>T synonymous_variant 0.15
clpC1 4038530 p.Glu725Asp missense_variant 0.16
clpC1 4038533 p.Arg724Lys missense_variant 0.16
clpC1 4038596 c.2109A>G synonymous_variant 0.19
clpC1 4038683 c.2022T>G synonymous_variant 0.15
clpC1 4038749 c.1956C>A synonymous_variant 0.17
clpC1 4038755 c.1950G>C synonymous_variant 0.17
clpC1 4038764 c.1941C>G synonymous_variant 0.18
clpC1 4038773 c.1932T>C synonymous_variant 0.16
clpC1 4038782 c.1923G>C synonymous_variant 0.14
clpC1 4038790 c.1915C>T synonymous_variant 0.17
clpC1 4038812 c.1893T>C synonymous_variant 0.15
clpC1 4038815 c.1890G>C synonymous_variant 0.16
clpC1 4038878 c.1827A>G synonymous_variant 0.21
clpC1 4038890 c.1815G>A synonymous_variant 0.21
clpC1 4038908 c.1797C>G synonymous_variant 0.18
clpC1 4038914 c.1791G>C synonymous_variant 0.18
clpC1 4038917 c.1788C>T synonymous_variant 0.18
clpC1 4038923 c.1782A>G synonymous_variant 0.24
clpC1 4038953 c.1752A>G synonymous_variant 0.25
clpC1 4038956 c.1749T>C synonymous_variant 0.29
clpC1 4038965 c.1740T>C synonymous_variant 0.22
clpC1 4038971 c.1734T>C synonymous_variant 0.18
clpC1 4038974 c.1731T>C synonymous_variant 0.18
clpC1 4038989 c.1716T>C synonymous_variant 0.2
clpC1 4038997 c.1708T>C synonymous_variant 0.19
clpC1 4039280 c.1425G>A synonymous_variant 0.16
clpC1 4039286 c.1419T>C synonymous_variant 0.21
clpC1 4039292 c.1413C>T synonymous_variant 0.21
clpC1 4039298 c.1407T>C synonymous_variant 0.21
clpC1 4039319 c.1386T>C synonymous_variant 0.17
clpC1 4039322 c.1383T>A synonymous_variant 0.19
clpC1 4039337 c.1368A>T synonymous_variant 0.15
clpC1 4039346 c.1359G>C synonymous_variant 0.16
clpC1 4039355 c.1350G>C synonymous_variant 0.17
clpC1 4039364 c.1341C>G synonymous_variant 0.15
clpC1 4039391 c.1314T>C synonymous_variant 0.15
clpC1 4039439 c.1266C>T synonymous_variant 0.17
clpC1 4039442 c.1263A>G synonymous_variant 0.17
clpC1 4039454 c.1251A>G synonymous_variant 0.22
clpC1 4039466 c.1239T>C synonymous_variant 0.21
clpC1 4039469 c.1236T>C synonymous_variant 0.22
clpC1 4039481 c.1224T>C synonymous_variant 0.22
clpC1 4039484 c.1221T>C synonymous_variant 0.21
clpC1 4039487 c.1218G>C synonymous_variant 0.21
clpC1 4039517 c.1188C>G synonymous_variant 0.15
clpC1 4039586 c.1119G>C synonymous_variant 0.19
clpC1 4039610 c.1095G>C synonymous_variant 0.2
clpC1 4039616 c.1089G>C synonymous_variant 0.21
clpC1 4039622 c.1083C>T synonymous_variant 0.2
clpC1 4040033 c.672G>C synonymous_variant 0.2
clpC1 4040090 c.613_615delTCTinsAGC synonymous_variant 0.18
clpC1 4040093 c.612C>G synonymous_variant 0.17
clpC1 4040105 c.600C>G synonymous_variant 0.18
clpC1 4040108 c.597G>C synonymous_variant 0.18
clpC1 4040126 c.579C>T synonymous_variant 0.15
clpC1 4040387 c.318A>G synonymous_variant 0.15
clpC1 4040393 c.312G>C synonymous_variant 0.16
clpC1 4040411 c.294T>C synonymous_variant 0.18
clpC1 4040423 c.282A>G synonymous_variant 0.18
clpC1 4040426 c.279T>C synonymous_variant 0.17
clpC1 4040431 c.274T>C synonymous_variant 0.15
clpC1 4040444 c.261C>T synonymous_variant 0.16
clpC1 4040450 c.255A>G synonymous_variant 0.16
clpC1 4040459 c.246C>G synonymous_variant 0.18
clpC1 4040462 c.243C>G synonymous_variant 0.16
clpC1 4040465 c.240T>C synonymous_variant 0.16
clpC1 4040471 c.234T>C synonymous_variant 0.16
clpC1 4040477 c.228G>A synonymous_variant 0.19
clpC1 4040480 c.225T>G synonymous_variant 0.19
embC 4240409 p.Pro183Ala missense_variant 0.31
embC 4240412 p.Leu184Val missense_variant 0.22
embC 4240671 p.Thr270Ile missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242970 c.-263C>T upstream_gene_variant 1.0
embA 4244220 c.988C>T synonymous_variant 1.0
embA 4245222 p.Tyr664Gln missense_variant 0.14
embB 4246551 p.Asn13Ser missense_variant 1.0
embB 4246864 c.351C>T synonymous_variant 1.0
embB 4247016 p.Ser168Trp missense_variant 0.28
embB 4247173 c.660G>A synonymous_variant 1.0
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4248328 c.1815G>C synonymous_variant 0.19
embB 4249487 c.2974T>C synonymous_variant 0.17
embB 4249498 c.2985G>C synonymous_variant 0.16
aftB 4267858 p.Ile327Val missense_variant 1.0
ubiA 4269209 p.Ser209Ala missense_variant 0.13
ubiA 4269243 p.His197Gln missense_variant 0.14
aftB 4269351 c.-515C>T upstream_gene_variant 1.0
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0