TB-Profiler result

Run: SRR7898221
Summary

Run ID: SRR7898221

Sample name:

Date: 15-08-2022 11:46:38

Number of reads: 4531910

Percentage reads mapped: 86.68

Strain: lineage1.1.2

Drug-resistance: MDR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1 Indo-Oceanic EAI RD239 0.99
lineage1.1 Indo-Oceanic EAI3;EAI4;EAI5;EAI6 RD239 0.97
lineage1.1.2 Indo-Oceanic EAI3;EAI5 RD239 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 0.98 rifampicin
fabG1 1673425 c.-15C>T upstream_gene_variant 1.0 isoniazid, ethionamide
eis 2715342 c.-10G>A upstream_gene_variant 1.0 kanamycin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 0.98
gyrB 6124 c.885C>T synonymous_variant 0.97
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7841 c.540C>G synonymous_variant 0.12
gyrA 7847 c.546G>T synonymous_variant 0.14
gyrA 8283 p.Ile328Leu missense_variant 0.13
gyrA 8324 c.1023T>C synonymous_variant 0.13
gyrA 8452 p.Ala384Val missense_variant 0.95
gyrA 8486 c.1185T>C synonymous_variant 0.13
gyrA 8489 c.1188A>G synonymous_variant 0.14
gyrA 8516 c.1215T>C synonymous_variant 0.14
gyrA 8537 c.1236G>A synonymous_variant 0.14
gyrA 8540 c.1239C>G synonymous_variant 0.13
gyrA 8546 c.1245T>C synonymous_variant 0.15
gyrA 8552 c.1251C>A synonymous_variant 0.15
gyrA 8555 c.1254G>C synonymous_variant 0.14
gyrA 8561 c.1260A>C synonymous_variant 0.13
gyrA 8603 c.1302A>C synonymous_variant 0.15
gyrA 8609 c.1308G>C synonymous_variant 0.15
gyrA 8619 c.1318T>C synonymous_variant 0.15
gyrA 8636 c.1335A>C synonymous_variant 0.15
gyrA 8642 c.1341A>G synonymous_variant 0.14
gyrA 8672 c.1371A>G synonymous_variant 0.14
gyrA 8678 c.1377G>A synonymous_variant 0.16
gyrA 8903 c.1602T>C synonymous_variant 0.14
gyrA 8933 c.1632G>A synonymous_variant 0.14
gyrA 9047 c.1746C>T synonymous_variant 0.95
gyrA 9143 c.1842T>C synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9443 c.2142G>A synonymous_variant 1.0
fgd1 491583 c.801G>A synonymous_variant 0.14
fgd1 491589 c.807G>A synonymous_variant 0.16
fgd1 491742 c.960T>C synonymous_variant 1.0
mshA 575935 c.588G>A synonymous_variant 0.16
mshA 575944 c.597T>G synonymous_variant 0.15
mshA 575953 c.606G>C synonymous_variant 0.13
mshA 576000 p.Asp218Ala missense_variant 0.91
rpoB 760106 c.300G>T synonymous_variant 0.13
rpoB 760118 c.312T>C synonymous_variant 0.14
rpoB 760196 c.390C>G synonymous_variant 0.14
rpoB 760235 c.429T>C synonymous_variant 0.13
rpoB 760424 c.618C>G synonymous_variant 0.13
rpoB 760430 c.624T>C synonymous_variant 0.15
rpoB 760434 p.Val210Ile missense_variant 0.15
rpoB 760475 c.669A>G synonymous_variant 0.14
rpoB 760490 c.684C>T synonymous_variant 0.89
rpoB 760591 p.Val262Ala missense_variant 0.14
rpoB 760611 c.805T>C synonymous_variant 0.17
rpoB 760661 c.855A>C synonymous_variant 0.14
rpoB 760670 c.864G>C synonymous_variant 0.15
rpoB 760674 c.868T>C synonymous_variant 0.14
rpoB 760679 c.873A>G synonymous_variant 0.15
rpoB 760683 c.877T>C synonymous_variant 0.16
rpoB 760716 c.910_912delCGCinsAGG synonymous_variant 0.19
rpoB 760727 c.921C>T synonymous_variant 0.18
rpoB 760730 c.924T>C synonymous_variant 0.16
rpoB 760757 c.951T>C synonymous_variant 0.13
rpoB 760769 c.963C>G synonymous_variant 0.13
rpoB 760946 c.1140A>G synonymous_variant 0.16
rpoB 760970 c.1164G>C synonymous_variant 0.14
rpoB 760971 c.1165_1167delCGGinsAGA synonymous_variant 0.14
rpoB 760982 c.1176G>C synonymous_variant 0.17
rpoB 760985 c.1179G>C synonymous_variant 0.17
rpoB 760991 c.1185G>C synonymous_variant 0.18
rpoB 761006 c.1200C>T synonymous_variant 0.17
rpoB 761537 c.1731C>G synonymous_variant 0.15
rpoB 761601 p.Ala599Thr missense_variant 0.33
rpoB 761636 c.1830G>T synonymous_variant 0.13
rpoB 761648 c.1842T>C synonymous_variant 0.12
rpoB 761948 c.2142G>C synonymous_variant 0.12
rpoB 761954 c.2148C>G synonymous_variant 0.12
rpoB 762284 c.2478G>C synonymous_variant 0.14
rpoB 762317 c.2511A>G synonymous_variant 0.12
rpoB 762329 c.2523G>C synonymous_variant 0.13
rpoC 762410 c.-960T>C upstream_gene_variant 0.14
rpoC 762416 c.-954A>G upstream_gene_variant 0.15
rpoC 762425 c.-945C>T upstream_gene_variant 0.15
rpoC 762434 c.-936T>C upstream_gene_variant 0.14
rpoC 762470 c.-900G>C upstream_gene_variant 0.17
rpoC 762491 c.-879T>C upstream_gene_variant 0.15
rpoB 762510 p.Ala902Pro missense_variant 0.18
rpoC 762533 c.-837T>C upstream_gene_variant 0.15
rpoC 762536 c.-834T>C upstream_gene_variant 0.15
rpoC 762537 c.-833T>C upstream_gene_variant 0.15
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763570 c.201G>C synonymous_variant 0.13
rpoC 763573 c.204G>C synonymous_variant 0.14
rpoC 763630 c.261G>T synonymous_variant 0.15
rpoC 763633 c.264T>C synonymous_variant 0.14
rpoC 763636 c.267T>C synonymous_variant 0.15
rpoC 763660 c.291T>G synonymous_variant 0.14
rpoC 763884 p.Ala172Val missense_variant 0.97
rpoC 763886 c.517C>A synonymous_variant 0.97
rpoC 764218 c.849C>T synonymous_variant 0.13
rpoC 764236 c.867G>A synonymous_variant 0.21
rpoC 764248 c.879C>G synonymous_variant 0.21
rpoC 764260 c.891G>A synonymous_variant 0.23
rpoC 764266 c.897T>C synonymous_variant 0.23
rpoC 764272 c.903G>T synonymous_variant 0.2
rpoC 764278 c.909A>G synonymous_variant 0.16
rpoC 764317 c.948C>G synonymous_variant 0.19
rpoC 764326 c.957G>C synonymous_variant 0.17
rpoC 764353 c.984G>C synonymous_variant 0.16
rpoC 764365 c.996C>T synonymous_variant 0.2
rpoC 764632 c.1263T>C synonymous_variant 0.13
rpoC 764668 c.1299C>T synonymous_variant 0.14
rpoC 764752 c.1383G>C synonymous_variant 0.13
rpoC 764791 c.1422C>A synonymous_variant 0.15
rpoC 764809 c.1440C>T synonymous_variant 0.16
rpoC 764815 c.1446A>G synonymous_variant 0.14
rpoC 764824 c.1455T>C synonymous_variant 0.16
rpoC 764872 c.1503A>G synonymous_variant 0.16
rpoC 764893 c.1524T>C synonymous_variant 0.22
rpoC 764932 c.1563C>G synonymous_variant 0.19
rpoC 764953 c.1584G>C synonymous_variant 0.15
rpoC 764968 c.1599T>C synonymous_variant 0.12
rpoC 765171 p.Pro601Leu missense_variant 1.0
rpoC 765404 c.2035C>T synonymous_variant 0.14
rpoC 765421 c.2052C>G synonymous_variant 0.13
rpoC 765454 c.2085C>G synonymous_variant 0.15
rpoC 765688 c.2319G>C synonymous_variant 0.17
rpoC 765689 c.2320C>T synonymous_variant 0.17
rpoC 765700 c.2331T>C synonymous_variant 0.15
rpoC 765734 c.2365T>C synonymous_variant 0.15
rpoC 765742 c.2373G>A synonymous_variant 0.14
rpoC 765772 c.2403C>G synonymous_variant 0.14
rpoC 765877 c.2508C>G synonymous_variant 0.16
rpoC 765883 c.2514C>G synonymous_variant 0.15
rpoC 765886 c.2517C>G synonymous_variant 0.15
rpoC 765892 c.2523T>C synonymous_variant 0.15
rpoC 766043 p.Gln892Glu missense_variant 0.14
rpoC 766054 c.2685C>T synonymous_variant 0.13
rpoC 766082 p.Ala905Gln missense_variant 0.14
rpoC 766312 c.2943T>G synonymous_variant 0.12
rpoC 766357 c.2988C>T synonymous_variant 0.16
rpoC 766366 c.2997C>G synonymous_variant 0.15
rpoC 766381 c.3012C>T synonymous_variant 0.14
rpoC 766384 c.3015A>G synonymous_variant 0.13
rpoC 766483 c.3114G>C synonymous_variant 0.13
rpoC 766486 c.3117A>C synonymous_variant 0.14
rpoC 766492 c.3123T>C synonymous_variant 0.14
rpoC 766607 p.Ile1080Leu missense_variant 0.14
rpoC 766630 c.3261G>C synonymous_variant 0.14
rpoC 766666 c.3297C>G synonymous_variant 0.17
rpoC 766672 c.3303T>C synonymous_variant 0.17
rpoC 766726 c.3357T>C synonymous_variant 0.2
rpoC 766735 c.3366G>T synonymous_variant 0.22
rpoC 766738 c.3369G>C synonymous_variant 0.18
rpoC 766747 c.3378C>G synonymous_variant 0.19
rpoC 766750 c.3381C>G synonymous_variant 0.19
rpoC 766765 c.3396A>C synonymous_variant 0.16
rpoC 766804 c.3435A>G synonymous_variant 0.15
rpoC 766843 c.3474T>C synonymous_variant 0.14
rpoC 766933 c.3564A>G synonymous_variant 0.12
rpoC 766945 c.3576A>G synonymous_variant 0.14
rpoC 766963 c.3594T>C synonymous_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776395 p.Phe696Leu missense_variant 1.0
mmpS5 778740 p.Val56Met missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781841 c.282C>G synonymous_variant 0.13
fbiC 1304991 c.2061G>C synonymous_variant 0.15
fbiC 1304994 c.2064A>G synonymous_variant 0.14
fbiC 1304995 p.Leu689Met missense_variant 0.14
fbiC 1305006 c.2076A>G synonymous_variant 0.15
fbiC 1305021 c.2091C>G synonymous_variant 0.13
fbiC 1305195 c.2265T>C synonymous_variant 0.16
fbiC 1305201 c.2271G>T synonymous_variant 0.16
fbiC 1305210 c.2280G>A synonymous_variant 0.14
fbiC 1305215 p.Ser762Thr missense_variant 0.13
fbiC 1305219 c.2289T>C synonymous_variant 0.13
embR 1417019 p.Cys110Tyr missense_variant 1.0
atpE 1460882 c.-163T>C upstream_gene_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.19
rrs 1471984 n.139T>A non_coding_transcript_exon_variant 0.21
rrl 1474083 n.426C>T non_coding_transcript_exon_variant 0.2
rrl 1474093 n.436G>A non_coding_transcript_exon_variant 0.2
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.17
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.2
rrl 1474111 n.454T>C non_coding_transcript_exon_variant 0.24
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.19
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.19
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.2
rrl 1474673 n.1016T>C non_coding_transcript_exon_variant 0.16
rrl 1474717 n.1060A>T non_coding_transcript_exon_variant 0.16
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.28
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.29
rrl 1474831 n.1174A>G non_coding_transcript_exon_variant 0.21
rrl 1475028 n.1371G>T non_coding_transcript_exon_variant 0.15
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.18
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.17
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.14
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.14
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.19
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.15
rrl 1475430 n.1773T>C non_coding_transcript_exon_variant 0.15
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 0.14
rrl 1475532 n.1875A>G non_coding_transcript_exon_variant 0.19
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.15
rrl 1475617 n.1960C>G non_coding_transcript_exon_variant 0.18
rrl 1475620 n.1964delT non_coding_transcript_exon_variant 0.18
rrl 1475625 n.1968G>C non_coding_transcript_exon_variant 0.18
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.16
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.12
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.16
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.17
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.18
rrl 1476106 n.2449A>G non_coding_transcript_exon_variant 0.23
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.3
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.29
rrl 1476251 n.2594T>C non_coding_transcript_exon_variant 0.16
rrl 1476256 n.2599A>C non_coding_transcript_exon_variant 0.19
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.18
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.18
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.15
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.16
rrl 1476711 n.3054G>A non_coding_transcript_exon_variant 0.14
rrl 1476719 n.3062C>T non_coding_transcript_exon_variant 0.14
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 0.14
rpsA 1833541 c.-1T>C upstream_gene_variant 0.13
rpsA 1833554 p.Thr5Ala missense_variant 0.14
rpsA 1833557 p.Val6Ile missense_variant 0.14
rpsA 1833595 c.54T>C synonymous_variant 0.13
rpsA 1833742 c.201A>G synonymous_variant 0.16
rpsA 1833745 c.204G>C synonymous_variant 0.16
rpsA 1833790 c.249T>C synonymous_variant 0.13
rpsA 1833793 c.252C>T synonymous_variant 0.13
rpsA 1833802 c.261A>G synonymous_variant 0.14
rpsA 1833811 c.270G>C synonymous_variant 0.15
rpsA 1833874 c.333T>C synonymous_variant 0.13
rpsA 1834051 c.510G>A synonymous_variant 0.15
rpsA 1834099 c.558C>G synonymous_variant 0.14
rpsA 1834102 c.561T>G synonymous_variant 0.13
rpsA 1834105 c.564C>G synonymous_variant 0.13
rpsA 1834336 c.795C>G synonymous_variant 0.12
rpsA 1834348 c.807T>C synonymous_variant 0.17
rpsA 1834366 c.825A>G synonymous_variant 0.18
rpsA 1834378 c.837T>C synonymous_variant 0.21
rpsA 1834411 c.870T>G synonymous_variant 0.23
rpsA 1834423 c.882G>C synonymous_variant 0.25
rpsA 1834450 c.909G>A synonymous_variant 0.23
rpsA 1834451 c.910T>C synonymous_variant 0.24
rpsA 1834465 c.924T>C synonymous_variant 0.18
rpsA 1834468 c.927A>G synonymous_variant 0.19
rpsA 1834489 c.948T>C synonymous_variant 0.14
rpsA 1834495 c.954G>A synonymous_variant 0.16
rpsA 1834522 c.981C>T synonymous_variant 0.16
rpsA 1834528 c.987T>G synonymous_variant 0.15
rpsA 1834546 c.1005T>C synonymous_variant 0.15
rpsA 1834555 c.1014T>C synonymous_variant 0.14
rpsA 1834556 p.Ala339Thr missense_variant 0.15
rpsA 1834598 c.1057C>T synonymous_variant 0.17
rpsA 1834609 c.1068T>C synonymous_variant 0.2
rpsA 1834624 c.1083G>C synonymous_variant 0.22
rpsA 1834633 c.1092A>G synonymous_variant 0.21
rpsA 1834639 c.1098T>C synonymous_variant 0.17
rpsA 1834660 c.1119C>T synonymous_variant 0.18
rpsA 1834669 c.1128G>C synonymous_variant 0.21
rpsA 1834687 c.1146C>T synonymous_variant 0.18
rpsA 1834720 c.1179C>G synonymous_variant 0.18
rpsA 1834732 c.1191T>C synonymous_variant 0.14
rpsA 1834733 p.Ala398Pro missense_variant 0.13
rpsA 1834753 c.1212T>G synonymous_variant 0.14
rpsA 1834774 c.1233C>T synonymous_variant 0.18
rpsA 1834780 c.1239A>G synonymous_variant 0.16
rpsA 1834786 c.1245A>G synonymous_variant 0.13
rpsA 1834789 c.1248T>C synonymous_variant 0.14
rpsA 1834792 c.1251G>C synonymous_variant 0.13
rpsA 1834798 c.1257C>G synonymous_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2167983 p.Gly877Asp missense_variant 1.0
Rv1979c 2222308 p.Asp286Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 1.0
kasA 2518705 c.591T>C synonymous_variant 0.13
kasA 2518714 c.600A>C synonymous_variant 0.13
kasA 2518756 c.642G>C synonymous_variant 0.14
kasA 2518783 c.669T>C synonymous_variant 0.13
kasA 2518789 c.675G>T synonymous_variant 0.15
kasA 2518795 c.681C>G synonymous_variant 0.18
kasA 2518798 c.684G>T synonymous_variant 0.17
kasA 2518825 c.711T>C synonymous_variant 0.16
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
folC 2746420 c.1179A>G synonymous_variant 0.15
folC 2746426 c.1173G>C synonymous_variant 0.16
folC 2746429 c.1170C>A synonymous_variant 0.15
folC 2746644 p.Arg319Ser missense_variant 1.0
Rv2752c 3064632 c.1560C>T synonymous_variant 0.98
Rv2752c 3065305 p.Ala296Val missense_variant 0.98
Rv2752c 3065901 c.291A>G synonymous_variant 0.13
Rv2752c 3065910 c.282C>G synonymous_variant 0.17
Rv2752c 3065916 c.276T>C synonymous_variant 0.18
Rv2752c 3065919 c.273G>C synonymous_variant 0.19
Rv2752c 3065947 p.Gly82Ala missense_variant 0.13
Rv2752c 3065949 c.243C>T synonymous_variant 0.14
Rv2752c 3065955 c.235_237delTTGinsCTC synonymous_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3448714 p.Asp71His missense_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474597 c.591C>A synonymous_variant 1.0
fprA 3475159 p.Asn385Asp missense_variant 1.0
rpoA 3877494 p.Glu338Asp missense_variant 0.12
rpoA 3877503 c.1005G>C synonymous_variant 0.13
rpoA 3877506 c.1002C>T synonymous_variant 0.13
rpoA 3877515 c.993G>C synonymous_variant 0.13
rpoA 3877557 c.951C>G synonymous_variant 0.16
rpoA 3877587 c.921A>G synonymous_variant 0.16
rpoA 3877593 c.915C>T synonymous_variant 0.13
rpoA 3877596 c.912G>C synonymous_variant 0.13
rpoA 3877650 c.858C>T synonymous_variant 0.13
rpoA 3877656 c.852T>C synonymous_variant 0.16
rpoA 3877668 c.840A>G synonymous_variant 0.18
rpoA 3877679 p.Ala277Ser missense_variant 0.16
rpoA 3877683 c.825G>T synonymous_variant 0.16
rpoA 3877686 c.822A>G synonymous_variant 0.16
rpoA 3877692 c.816G>C synonymous_variant 0.18
rpoA 3877704 c.804G>C synonymous_variant 0.16
rpoA 3878355 c.153C>G synonymous_variant 0.12
rpoA 3878364 c.144A>C synonymous_variant 0.13
rpoA 3878367 c.141C>T synonymous_variant 0.14
rpoA 3878370 c.138T>C synonymous_variant 0.14
rpoA 3878385 c.123C>G synonymous_variant 0.14
ddn 3987057 p.Arg72Trp missense_variant 0.97
clpC1 4038658 p.Lys683Gln missense_variant 0.18
clpC1 4038661 p.Ser682Thr missense_variant 0.16
clpC1 4038662 c.2043T>C synonymous_variant 0.16
clpC1 4038671 c.2034T>C synonymous_variant 0.17
clpC1 4038683 c.2022T>G synonymous_variant 0.21
clpC1 4038695 c.2010C>G synonymous_variant 0.21
clpC1 4038701 c.2004G>T synonymous_variant 0.23
clpC1 4038704 c.2001T>C synonymous_variant 0.22
clpC1 4038713 c.1992T>C synonymous_variant 0.25
clpC1 4038908 c.1797C>G synonymous_variant 0.2
clpC1 4038914 c.1791G>C synonymous_variant 0.18
clpC1 4038917 c.1788C>T synonymous_variant 0.19
clpC1 4038923 c.1780_1782delCTAinsTTG synonymous_variant 0.21
clpC1 4038953 c.1752A>G synonymous_variant 0.14
clpC1 4038956 c.1749T>C synonymous_variant 0.15
clpC1 4038965 c.1740T>C synonymous_variant 0.19
clpC1 4038971 c.1734T>C synonymous_variant 0.15
clpC1 4039217 c.1488G>A synonymous_variant 0.14
clpC1 4039243 c.1462C>T synonymous_variant 0.15
clpC1 4039661 c.1044T>G synonymous_variant 0.16
clpC1 4039664 c.1041G>C synonymous_variant 0.16
clpC1 4040165 c.540G>C synonymous_variant 0.13
clpC1 4040171 c.534C>G synonymous_variant 0.14
clpC1 4040180 c.525C>G synonymous_variant 0.15
clpC1 4040201 c.504C>A synonymous_variant 0.15
clpC1 4040315 c.390G>A synonymous_variant 0.16
clpC1 4040517 p.Val63Ala missense_variant 0.89
embC 4240671 p.Thr270Ile missense_variant 1.0
embC 4241042 p.Asn394Asp missense_variant 0.91
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243848 p.Val206Met missense_variant 1.0
embA 4245969 p.Pro913Ser missense_variant 0.98
embB 4247646 p.Glu378Ala missense_variant 1.0
embB 4247991 p.Val493Ala missense_variant 0.98
ubiA 4269387 p.Glu149Asp missense_variant 1.0
aftB 4269606 c.-770T>C upstream_gene_variant 0.96
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407873 c.330G>T synonymous_variant 1.0
gid 4408094 p.Gly37Arg missense_variant 0.99