TB-Profiler result

Run: SRR6785268
Summary

Run ID: SRR6785268

Sample name:

Date: 04-04-2023 15:41:10

Number of reads: 2567898

Percentage reads mapped: 82.12

Strain: lineage4.2.1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.99
lineage4.2 Euro-American H;T;LAM None 0.95
lineage4.2.1 Euro-American (TUR) H3;H4 None 0.97
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6238 c.999G>A synonymous_variant 0.2
gyrB 6242 p.Arg335Asn missense_variant 0.2
gyrB 6250 c.1011A>G synonymous_variant 0.19
gyrB 6256 c.1017G>A synonymous_variant 0.2
gyrB 6268 c.1029C>G synonymous_variant 0.18
gyrB 6280 c.1041T>C synonymous_variant 0.18
gyrB 6286 c.1047T>C synonymous_variant 0.17
gyrB 6289 c.1050C>T synonymous_variant 0.17
gyrB 6292 c.1053G>C synonymous_variant 0.17
gyrA 6307 c.-995T>G upstream_gene_variant 0.18
gyrA 6362 c.-940T>C upstream_gene_variant 0.18
gyrA 6379 c.-923C>G upstream_gene_variant 0.13
gyrA 6670 c.-632G>C upstream_gene_variant 0.15
gyrA 6673 c.-629A>C upstream_gene_variant 0.15
gyrA 6676 c.-626T>G upstream_gene_variant 0.15
gyrA 6700 c.-602T>C upstream_gene_variant 0.16
gyrA 6703 c.-599G>C upstream_gene_variant 0.17
gyrA 6709 c.-593A>G upstream_gene_variant 0.17
gyrA 6712 c.-590G>C upstream_gene_variant 0.17
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7394 c.93T>C synonymous_variant 0.13
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 490905 c.123T>C synonymous_variant 0.14
fgd1 490911 c.129T>G synonymous_variant 0.13
fgd1 490917 c.135C>G synonymous_variant 0.13
fgd1 491001 c.219G>C synonymous_variant 0.15
fgd1 491007 c.225G>C synonymous_variant 0.16
fgd1 491013 c.231C>G synonymous_variant 0.17
fgd1 491043 c.261T>G synonymous_variant 0.15
fgd1 491049 c.267T>C synonymous_variant 0.14
fgd1 491247 c.465C>T synonymous_variant 0.89
fgd1 491535 c.753G>C synonymous_variant 0.16
fgd1 491542 c.760T>C synonymous_variant 0.17
fgd1 491547 c.765A>C synonymous_variant 0.16
fgd1 491550 c.768T>C synonymous_variant 0.15
fgd1 491553 c.771G>A synonymous_variant 0.17
fgd1 491601 c.819T>C synonymous_variant 0.17
fgd1 491610 c.828A>G synonymous_variant 0.18
fgd1 491616 c.834A>G synonymous_variant 0.18
fgd1 491620 p.Ile280Val missense_variant 0.17
fgd1 491643 c.861G>A synonymous_variant 0.16
fgd1 491646 c.864G>C synonymous_variant 0.17
fgd1 491649 c.867C>T synonymous_variant 0.18
fgd1 491658 c.876A>G synonymous_variant 0.17
fgd1 491661 c.879C>G synonymous_variant 0.17
fgd1 491673 c.891A>C synonymous_variant 0.17
fgd1 491676 c.894T>C synonymous_variant 0.15
fgd1 491742 c.960T>C synonymous_variant 0.15
mshA 575746 c.399C>G synonymous_variant 0.13
mshA 575770 c.423G>A synonymous_variant 0.16
mshA 575771 p.Val142Ser missense_variant 0.16
mshA 575779 c.432A>G synonymous_variant 0.21
mshA 575782 c.435G>C synonymous_variant 0.2
mshA 575812 c.465C>T synonymous_variant 0.15
mshA 575821 c.474G>C synonymous_variant 0.17
mshA 575824 c.477T>G synonymous_variant 0.17
mshA 575830 c.483C>G synonymous_variant 0.16
mshA 575833 c.486C>G synonymous_variant 0.14
mshA 575845 c.498C>T synonymous_variant 0.14
mshA 575884 c.537G>C synonymous_variant 0.18
mshA 575887 c.540G>C synonymous_variant 0.18
mshA 575893 c.546C>G synonymous_variant 0.18
mshA 575896 c.549G>C synonymous_variant 0.17
mshA 575908 c.561A>G synonymous_variant 0.19
mshA 575917 p.Asp190Glu missense_variant 0.16
mshA 575920 c.573C>G synonymous_variant 0.16
mshA 576108 p.Ala254Gly missense_variant 0.2
ccsA 620340 c.450C>G synonymous_variant 0.14
ccsA 620346 c.456C>G synonymous_variant 0.19
ccsA 620362 p.Ala158Thr missense_variant 0.17
ccsA 620367 c.477T>C synonymous_variant 0.19
ccsA 620373 c.483C>G synonymous_variant 0.19
ccsA 620376 c.486G>C synonymous_variant 0.18
ccsA 620385 c.495G>C synonymous_variant 0.18
ccsA 620388 c.498A>G synonymous_variant 0.17
ccsA 620389 c.499C>T synonymous_variant 0.17
ccsA 620412 c.522T>C synonymous_variant 0.17
ccsA 620415 c.525T>C synonymous_variant 0.16
ccsA 620421 c.531G>C synonymous_variant 0.13
ccsA 620424 c.534G>C synonymous_variant 0.18
ccsA 620433 c.543C>G synonymous_variant 0.17
ccsA 620682 c.792G>A synonymous_variant 0.14
ccsA 620688 c.798G>C synonymous_variant 0.14
rpoB 760235 c.429T>C synonymous_variant 0.14
rpoB 760283 c.477G>C synonymous_variant 0.21
rpoB 760298 c.492G>C synonymous_variant 0.19
rpoB 760307 c.501T>C synonymous_variant 0.19
rpoB 760310 c.504G>C synonymous_variant 0.19
rpoB 760328 c.522G>C synonymous_variant 0.19
rpoB 760331 c.525G>C synonymous_variant 0.2
rpoB 760340 c.534G>T synonymous_variant 0.21
rpoB 760361 c.555T>C synonymous_variant 0.15
rpoB 760370 c.564C>G synonymous_variant 0.14
rpoB 760376 p.Asp190Glu missense_variant 0.15
rpoB 760380 p.Thr192Leu missense_variant 0.15
rpoB 760406 c.600G>C synonymous_variant 0.13
rpoB 760475 c.669A>G synonymous_variant 0.17
rpoB 760481 c.675G>C synonymous_variant 0.16
rpoB 760484 c.678A>G synonymous_variant 0.15
rpoB 760522 p.Ser239Asn missense_variant 0.16
rpoB 760541 c.735G>C synonymous_variant 0.14
rpoB 760547 c.741G>C synonymous_variant 0.15
rpoB 760563 p.Arg253Met missense_variant 0.15
rpoB 760591 p.Val262Ala missense_variant 0.15
rpoB 760718 c.912C>T synonymous_variant 0.14
rpoB 760724 c.918T>C synonymous_variant 0.14
rpoB 761006 c.1200C>G synonymous_variant 0.13
rpoB 761015 c.1209G>C synonymous_variant 0.15
rpoB 761021 c.1215G>C synonymous_variant 0.14
rpoB 761027 c.1221A>G synonymous_variant 0.14
rpoB 761102 c.1296A>G synonymous_variant 0.2
rpoB 761129 c.1323G>C synonymous_variant 0.14
rpoB 761132 c.1326G>T synonymous_variant 0.14
rpoB 761133 c.1327T>C synonymous_variant 0.15
rpoB 761150 c.1344A>C synonymous_variant 0.17
rpoB 761153 c.1347G>C synonymous_variant 0.16
rpoB 761165 c.1359G>C synonymous_variant 0.13
rpoB 761180 c.1374A>C synonymous_variant 0.14
rpoB 761189 c.1383T>C synonymous_variant 0.17
rpoB 761195 c.1389G>C synonymous_variant 0.18
rpoB 761207 c.1401C>T synonymous_variant 0.17
rpoB 761213 c.1407G>C synonymous_variant 0.15
rpoB 761219 c.1413G>C synonymous_variant 0.16
rpoB 761408 c.1602G>C synonymous_variant 0.15
rpoB 761477 c.1671C>G synonymous_variant 0.14
rpoB 761510 c.1704T>C synonymous_variant 0.15
rpoB 761570 c.1764T>C synonymous_variant 0.14
rpoB 761573 c.1767C>G synonymous_variant 0.14
rpoB 761579 c.1773G>C synonymous_variant 0.14
rpoB 761588 c.1782C>T synonymous_variant 0.14
rpoB 761765 c.1959T>C synonymous_variant 0.14
rpoB 761772 p.His656Ala missense_variant 0.15
rpoB 761778 p.Asn658Asp missense_variant 0.15
rpoB 761791 p.Arg662His missense_variant 0.14
rpoB 762083 c.2277T>C synonymous_variant 0.14
rpoB 762086 c.2280G>C synonymous_variant 0.13
rpoB 762317 c.2511A>G synonymous_variant 0.15
rpoB 762329 c.2523G>C synonymous_variant 0.14
rpoC 762929 c.-441G>C upstream_gene_variant 0.14
rpoC 762989 c.-381G>C upstream_gene_variant 0.17
rpoC 762995 c.-375G>T upstream_gene_variant 0.17
rpoC 763013 c.-357C>G upstream_gene_variant 0.2
rpoC 763025 c.-345C>T upstream_gene_variant 0.2
rpoC 763028 c.-342T>C upstream_gene_variant 0.21
rpoC 763031 c.-339T>G upstream_gene_variant 0.22
rpoC 763034 c.-336C>G upstream_gene_variant 0.2
rpoC 763040 c.-330C>G upstream_gene_variant 0.21
rpoC 763070 c.-300T>C upstream_gene_variant 0.19
rpoC 763085 c.-285C>G upstream_gene_variant 0.19
rpoC 763115 c.-255T>C upstream_gene_variant 0.14
rpoC 763136 c.-234C>T upstream_gene_variant 0.14
rpoC 763148 c.-222G>C upstream_gene_variant 0.14
rpoC 763402 c.33C>G synonymous_variant 0.16
rpoC 763411 c.42T>G synonymous_variant 0.18
rpoC 763414 c.45T>C synonymous_variant 0.18
rpoC 763441 c.72C>T synonymous_variant 0.18
rpoC 763444 c.75T>C synonymous_variant 0.19
rpoC 763456 c.87A>G synonymous_variant 0.19
rpoC 763486 c.117T>G synonymous_variant 0.21
rpoC 763528 c.159G>A synonymous_variant 0.21
rpoC 763546 c.177A>G synonymous_variant 0.21
rpoC 763570 c.201G>C synonymous_variant 0.16
rpoC 763573 c.204G>C synonymous_variant 0.15
rpoC 763594 c.225C>T synonymous_variant 0.19
rpoC 763603 c.234C>T synonymous_variant 0.17
rpoC 763636 c.267T>C synonymous_variant 0.24
rpoC 763660 c.291T>G synonymous_variant 0.23
rpoC 763675 c.306C>G synonymous_variant 0.21
rpoC 763696 c.327T>C synonymous_variant 0.22
rpoC 763702 c.333C>G synonymous_variant 0.2
rpoC 763717 c.348T>C synonymous_variant 0.2
rpoC 763723 c.354G>C synonymous_variant 0.2
rpoC 763732 c.363C>G synonymous_variant 0.18
rpoC 763741 c.372C>T synonymous_variant 0.17
rpoC 763744 c.375G>C synonymous_variant 0.17
rpoC 763765 c.396T>C synonymous_variant 0.2
rpoC 763774 c.405G>C synonymous_variant 0.19
rpoC 763807 c.438T>C synonymous_variant 0.17
rpoC 763816 c.447C>G synonymous_variant 0.14
rpoC 764257 c.888G>C synonymous_variant 0.14
rpoC 764266 c.897T>C synonymous_variant 0.13
rpoC 764338 c.969G>A synonymous_variant 0.15
rpoC 764353 c.984G>C synonymous_variant 0.15
rpoC 764365 c.996C>T synonymous_variant 0.15
rpoC 764405 c.1036A>C synonymous_variant 0.19
rpoC 764419 c.1050C>G synonymous_variant 0.19
rpoC 764428 c.1059G>C synonymous_variant 0.18
rpoC 764431 c.1062G>C synonymous_variant 0.19
rpoC 764434 c.1065A>G synonymous_variant 0.19
rpoC 764446 c.1077T>C synonymous_variant 0.16
rpoC 764449 c.1080G>C synonymous_variant 0.15
rpoC 764452 c.1083T>C synonymous_variant 0.15
rpoC 764458 c.1089G>C synonymous_variant 0.16
rpoC 764461 c.1092A>G synonymous_variant 0.16
rpoC 764489 c.1120C>T synonymous_variant 0.14
rpoC 764593 c.1224C>T synonymous_variant 0.13
rpoC 764651 p.Ser428Thr missense_variant 0.13
rpoC 764932 c.1563C>A synonymous_variant 0.15
rpoC 764935 c.1566T>C synonymous_variant 0.15
rpoC 765319 c.1950A>G synonymous_variant 0.13
rpoC 765327 p.His653Pro missense_variant 0.13
rpoC 765329 p.Ser654Gly missense_variant 0.14
rpoC 765383 p.Met672Leu missense_variant 0.15
rpoC 765404 p.Leu679Val missense_variant 0.15
rpoC 765937 c.2568T>C synonymous_variant 0.16
rpoC 765982 c.2613C>G synonymous_variant 0.16
rpoC 765994 c.2625A>T synonymous_variant 0.17
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.16
rpoC 766021 c.2652G>C synonymous_variant 0.19
rpoC 766027 c.2658G>C synonymous_variant 0.19
rpoC 766043 p.Gln892Glu missense_variant 0.17
rpoC 766054 c.2685C>G synonymous_variant 0.17
rpoC 766597 c.3228C>G synonymous_variant 0.13
rpoC 766607 p.Ile1080Leu missense_variant 0.15
rpoC 766630 c.3261G>C synonymous_variant 0.16
rpoC 766726 c.3357T>C synonymous_variant 0.14
rpoC 766738 c.3369G>C synonymous_variant 0.17
rpoC 766774 c.3405T>C synonymous_variant 0.21
rpoC 766801 c.3432C>G synonymous_variant 0.18
rpoC 766804 c.3435A>G synonymous_variant 0.17
rpoC 766861 c.3492G>C synonymous_variant 0.21
rpoC 766864 c.3495G>C synonymous_variant 0.21
rpoC 766867 c.3498C>G synonymous_variant 0.15
rpoC 766885 c.3516G>A synonymous_variant 0.15
rpoC 766894 c.3525T>C synonymous_variant 0.15
rpoC 766900 c.3531T>C synonymous_variant 0.15
rpoC 766933 c.3564A>G synonymous_variant 0.15
rpoC 766945 c.3576A>G synonymous_variant 0.18
rpoC 766963 c.3594T>C synonymous_variant 0.15
rpoC 766972 c.3603G>C synonymous_variant 0.17
rpoC 766996 c.3627C>T synonymous_variant 0.13
rpoC 767059 c.3690T>G synonymous_variant 0.14
rpoC 767062 c.3693C>A synonymous_variant 0.15
rpoC 767098 c.3729T>C synonymous_variant 0.14
rpoC 767119 c.3750A>G synonymous_variant 0.17
rpoC 767134 c.3765C>A synonymous_variant 0.15
rpoC 767158 c.3789T>C synonymous_variant 0.17
rpoC 767180 p.Ala1271Gln missense_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781700 c.141G>C synonymous_variant 0.14
rpsL 781703 c.144G>T synonymous_variant 0.13
rpsL 781715 c.156T>C synonymous_variant 0.16
rpsL 781728 c.169T>C synonymous_variant 0.16
rpsL 781736 c.177T>C synonymous_variant 0.13
rpsL 781742 c.183C>T synonymous_variant 0.14
rpsL 781748 c.189C>G synonymous_variant 0.14
rpsL 781808 c.249C>T synonymous_variant 0.14
rpsL 781811 c.252C>T synonymous_variant 0.14
rpsL 781832 c.273T>C synonymous_variant 0.14
rpsL 781838 c.279G>C synonymous_variant 0.15
rpsL 781841 c.282C>G synonymous_variant 0.17
rpsL 781865 c.306G>C synonymous_variant 0.15
rpsL 781868 c.309T>C synonymous_variant 0.15
rpsL 781871 c.312G>C synonymous_variant 0.14
rpsL 781877 c.318T>C synonymous_variant 0.14
rpsL 781898 c.339A>T synonymous_variant 0.15
rpsL 781916 c.357T>C synonymous_variant 0.15
rpsL 781929 p.Gly124Ser missense_variant 0.17
rplC 800612 c.-197A>G upstream_gene_variant 0.14
rplC 800618 c.-191T>C upstream_gene_variant 0.14
rplC 800648 c.-161A>T upstream_gene_variant 0.14
rplC 800654 c.-155T>C upstream_gene_variant 0.15
rplC 800693 c.-116A>G upstream_gene_variant 0.18
rplC 800703 c.-106T>C upstream_gene_variant 0.16
rplC 800715 c.-94A>C upstream_gene_variant 0.15
rplC 800720 c.-89T>C upstream_gene_variant 0.16
rplC 800723 c.-86C>G upstream_gene_variant 0.16
rplC 800747 c.-62C>G upstream_gene_variant 0.14
rplC 800814 c.6A>G synonymous_variant 0.14
rplC 800817 c.9A>T synonymous_variant 0.14
rplC 800907 c.99C>G synonymous_variant 0.14
fbiC 1303818 c.888C>G synonymous_variant 0.16
fbiC 1303836 c.906G>C synonymous_variant 0.19
fbiC 1303845 c.915C>G synonymous_variant 0.21
fbiC 1303846 p.Phe306Val missense_variant 0.21
fbiC 1303854 c.924T>C synonymous_variant 0.19
fbiC 1303860 c.930A>C synonymous_variant 0.18
fbiC 1303884 c.954T>G synonymous_variant 0.19
fbiC 1303905 c.975G>C synonymous_variant 0.2
fbiC 1303914 c.984C>G synonymous_variant 0.22
fbiC 1303920 c.990C>T synonymous_variant 0.22
fbiC 1303944 c.1014G>C synonymous_variant 0.17
fbiC 1303947 c.1017T>G synonymous_variant 0.16
fbiC 1303948 p.Gly340Arg missense_variant 0.16
fbiC 1303953 p.Asp341Glu missense_variant 0.16
fbiC 1303956 c.1026A>G synonymous_variant 0.16
fbiC 1303961 p.Arg344Leu missense_variant 0.16
fbiC 1303971 c.1041T>C synonymous_variant 0.16
fbiC 1303980 c.1050G>A synonymous_variant 0.2
fbiC 1303998 c.1068T>G synonymous_variant 0.21
fbiC 1304004 c.1074A>G synonymous_variant 0.21
fbiC 1304008 c.1078T>C synonymous_variant 0.21
fbiC 1304022 c.1092T>C synonymous_variant 0.16
fbiC 1304031 c.1101C>G synonymous_variant 0.18
fbiC 1304034 c.1104A>G synonymous_variant 0.18
fbiC 1304040 c.1110C>G synonymous_variant 0.17
fbiC 1304046 c.1116C>G synonymous_variant 0.17
fbiC 1304049 c.1119T>C synonymous_variant 0.17
fbiC 1304050 c.1120T>C synonymous_variant 0.17
fbiC 1304058 c.1128G>A synonymous_variant 0.14
fbiC 1304059 c.1129C>T synonymous_variant 0.14
fbiC 1304064 c.1134G>C synonymous_variant 0.14
fbiC 1304067 c.1137G>C synonymous_variant 0.15
fbiC 1304085 c.1155C>T synonymous_variant 0.16
fbiC 1304091 p.Asp387Glu missense_variant 0.14
fbiC 1304092 p.Met388Leu missense_variant 0.15
fbiC 1304097 c.1167G>C synonymous_variant 0.19
fbiC 1304646 c.1716T>C synonymous_variant 0.14
fbiC 1304661 c.1731C>T synonymous_variant 0.13
fbiC 1304703 c.1773C>G synonymous_variant 0.13
fbiC 1304893 p.Gly655Ser missense_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.13
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.13
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.14
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.14
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.14
rpsA 1833661 c.120A>G synonymous_variant 0.14
rpsA 1833667 c.126C>G synonymous_variant 0.14
rpsA 1833721 c.180A>G synonymous_variant 0.18
rpsA 1833724 c.183C>G synonymous_variant 0.17
rpsA 1833727 c.186G>C synonymous_variant 0.17
rpsA 1833742 c.201A>G synonymous_variant 0.17
rpsA 1833745 c.204G>C synonymous_variant 0.16
rpsA 1833748 c.207C>G synonymous_variant 0.16
rpsA 1833847 c.306C>G synonymous_variant 0.13
rpsA 1833874 c.333T>C synonymous_variant 0.14
rpsA 1833886 c.345C>G synonymous_variant 0.14
rpsA 1833928 c.387G>C synonymous_variant 0.19
rpsA 1833940 c.399C>G synonymous_variant 0.19
rpsA 1833971 c.430C>T synonymous_variant 0.15
rpsA 1833979 c.438T>C synonymous_variant 0.17
rpsA 1834000 c.459G>C synonymous_variant 0.13
rpsA 1834081 c.540C>T synonymous_variant 0.17
rpsA 1834105 c.564C>G synonymous_variant 0.14
rpsA 1834108 c.567C>G synonymous_variant 0.14
rpsA 1834123 c.582C>G synonymous_variant 0.15
rpsA 1834451 c.910T>C synonymous_variant 0.15
rpsA 1834465 c.924T>C synonymous_variant 0.14
rpsA 1834468 c.927A>G synonymous_variant 0.14
rpsA 1834489 c.948T>C synonymous_variant 0.15
rpsA 1834513 c.972C>G synonymous_variant 0.13
rpsA 1834528 c.987T>C synonymous_variant 0.13
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918036 p.Arg33Ser missense_variant 0.14
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2170266 p.Gly116Asp missense_variant 1.0
PPE35 2170271 c.342T>C synonymous_variant 1.0
PPE35 2170308 p.Leu102Ala missense_variant 0.9
PPE35 2170313 c.300G>C synonymous_variant 0.91
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2517989 c.-126T>C upstream_gene_variant 0.14
kasA 2517993 c.-122G>T upstream_gene_variant 0.14
kasA 2518732 c.618C>G synonymous_variant 0.13
kasA 2518789 c.675G>C synonymous_variant 0.14
kasA 2518792 c.678C>A synonymous_variant 0.14
kasA 2518795 c.681C>G synonymous_variant 0.14
kasA 2519137 c.1023T>G synonymous_variant 0.14
kasA 2519158 c.1044C>T synonymous_variant 0.14
kasA 2519173 c.1059C>G synonymous_variant 0.14
ahpC 2726591 c.399C>G synonymous_variant 0.13
ahpC 2726593 p.Val134Ala missense_variant 0.13
ahpC 2726638 p.Ala149Val missense_variant 0.13
folC 2746308 p.Arg431Ser missense_variant 0.13
ribD 2986910 c.72C>A synonymous_variant 1.0
thyX 3067284 p.Ala221Gly missense_variant 0.13
thyX 3067286 c.660C>G synonymous_variant 0.13
thyX 3067289 c.657C>G synonymous_variant 0.13
thyX 3067295 c.651C>T synonymous_variant 0.13
thyX 3067316 c.630A>G synonymous_variant 0.15
thyX 3067325 c.621A>G synonymous_variant 0.17
thyX 3067349 c.597G>C synonymous_variant 0.16
thyX 3067355 c.591A>C synonymous_variant 0.18
thyX 3067367 c.579G>C synonymous_variant 0.16
thyX 3067373 c.573C>G synonymous_variant 0.16
thyX 3067376 c.570G>A synonymous_variant 0.17
thyX 3067391 c.555G>C synonymous_variant 0.22
thyX 3067394 c.552G>C synonymous_variant 0.22
thyX 3067439 c.507A>G synonymous_variant 0.32
thyX 3067445 c.501C>G synonymous_variant 0.34
thyX 3067457 c.489C>G synonymous_variant 0.38
thyX 3067465 p.Ile161Val missense_variant 0.41
thyX 3067475 c.471A>G synonymous_variant 0.38
thyX 3067490 c.456C>G synonymous_variant 0.42
thyX 3067493 c.453A>G synonymous_variant 0.44
thyX 3067515 p.Ser144Thr missense_variant 0.33
thyX 3067530 p.Ala139Ser missense_variant 0.29
thyX 3067545 p.Glu134Ala missense_variant 0.3
thyX 3067549 p.Thr133Ala missense_variant 0.27
thyX 3067556 p.His130Gln missense_variant 0.27
thyX 3067559 c.387C>G synonymous_variant 0.26
thyX 3067565 p.Asp127Glu missense_variant 0.24
thyX 3067570 p.Ala126Pro missense_variant 0.2
thyX 3067577 c.369G>A synonymous_variant 0.21
thyX 3067583 c.363C>G synonymous_variant 0.19
thyX 3067601 p.Arg115His missense_variant 0.19
thyX 3067611 p.Lys112Thr missense_variant 0.19
thyX 3067619 c.327A>C synonymous_variant 0.2
thyX 3067631 c.315C>G synonymous_variant 0.16
thyX 3067634 c.312C>G synonymous_variant 0.16
thyX 3067652 c.294T>C synonymous_variant 0.18
thyX 3067661 c.285C>G synonymous_variant 0.17
thyX 3067685 c.261A>C synonymous_variant 0.19
thyX 3067691 p.Ile85Leu missense_variant 0.16
thyX 3067694 c.252G>C synonymous_variant 0.14
thyX 3067718 c.228C>G synonymous_variant 0.15
thyX 3067721 c.225T>C synonymous_variant 0.15
thyX 3067736 c.210C>T synonymous_variant 0.13
thyX 3067772 c.174C>G synonymous_variant 0.14
thyX 3067781 c.165C>A synonymous_variant 0.15
thyX 3067793 c.153T>C synonymous_variant 0.13
thyX 3067799 c.147G>A synonymous_variant 0.15
thyX 3067802 c.144C>G synonymous_variant 0.18
thyX 3067814 c.132T>C synonymous_variant 0.17
thyX 3067850 c.96A>C synonymous_variant 0.17
thyX 3067869 p.Thr26Ser missense_variant 0.17
thyX 3067874 c.72C>G synonymous_variant 0.17
thyX 3067883 c.63C>G synonymous_variant 0.16
thyX 3067886 c.60A>C synonymous_variant 0.17
thyX 3067889 c.57C>G synonymous_variant 0.15
thyX 3067898 p.Asp16Glu missense_variant 0.15
thyA 3073953 c.519T>C synonymous_variant 0.14
ald 3086742 c.-78A>C upstream_gene_variant 0.91
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3877743 c.765T>C synonymous_variant 0.14
rpoA 3877782 c.726T>C synonymous_variant 0.13
rpoA 3877791 c.717C>G synonymous_variant 0.14
rpoA 3878001 c.507A>G synonymous_variant 0.13
rpoA 3878022 c.486T>C synonymous_variant 0.15
rpoA 3878028 c.480G>C synonymous_variant 0.15
rpoA 3878031 c.477T>C synonymous_variant 0.15
rpoA 3878040 c.468T>C synonymous_variant 0.13
rpoA 3878043 c.465G>A synonymous_variant 0.13
clpC1 4039103 c.1602T>C synonymous_variant 0.13
clpC1 4039112 c.1593C>G synonymous_variant 0.14
clpC1 4039121 c.1584T>C synonymous_variant 0.15
clpC1 4039142 c.1563A>G synonymous_variant 0.16
clpC1 4039145 c.1560G>C synonymous_variant 0.16
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242754 c.-479G>C upstream_gene_variant 0.13
embA 4245189 c.1957C>T synonymous_variant 0.13
embB 4247464 c.951C>G synonymous_variant 0.14
embB 4247470 c.957T>C synonymous_variant 0.15
embB 4247491 c.978G>C synonymous_variant 0.17
embB 4247497 c.984T>C synonymous_variant 0.17
embB 4247512 c.999T>C synonymous_variant 0.15
embB 4249594 c.3081G>A synonymous_variant 0.97
ethA 4328376 c.-903G>C upstream_gene_variant 0.96
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
PPE35 2167033 c.346_*615del stop_lost&conservative_inframe_deletion&splice_region_variant 1.0