TB-Profiler result

Run: SRR6785268
Summary

Run ID: SRR6785268

Sample name:

Date: 2025-09-15T18:57:36.248444

Number of reads: 2567898

Percentage reads mapped: 82.12

Median coverage: 61.0

Strain: lineage4.2.1

Spoligotype:

Drug-resistance: Sensitive

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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage4 Euro-American None 100.0
lineage4.2 Euro-American None 94.92
lineage4.2.1 Euro-American (TUR) None 97.32
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6238 c.999G>A synonymous_variant 0.2 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Asn missense_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6250 c.1011A>G synonymous_variant 0.19 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6256 c.1017G>A synonymous_variant 0.2 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6268 c.1029C>G synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6280 c.1041T>C synonymous_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6286 c.1047T>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6289 c.1050C>T synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6292 c.1053G>C synonymous_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrB 6307 c.1068T>G synonymous_variant 0.18 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6362 c.-940T>C upstream_gene_variant 0.18 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6379 c.-923C>G upstream_gene_variant 0.13 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6670 c.-632G>C upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6673 c.-629A>C upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6676 c.-626T>G upstream_gene_variant 0.15 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6700 c.-602T>C upstream_gene_variant 0.16 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6703 c.-599G>C upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6709 c.-593A>G upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 6712 c.-590G>C upstream_gene_variant 0.17 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7394 c.93T>C synonymous_variant 0.13 levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 9304 p.Gly668Asp missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
fgd1 490905 c.123T>C synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 490911 c.129T>G synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 490917 c.135C>G synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491001 c.219G>C synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491007 c.225G>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491013 c.231C>G synonymous_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491043 c.261T>G synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491049 c.267T>C synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491247 c.465C>T synonymous_variant 0.89 clofazimine Not assoc w R - Interim
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
fgd1 491535 c.753G>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491542 c.760T>C synonymous_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491547 c.765A>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491550 c.768T>C synonymous_variant 0.15 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491553 c.771G>A synonymous_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fgd1 491742 c.960T>C synonymous_variant 0.15 clofazimine Not assoc w R
delamanid Not assoc w R - Interim
pretomanid Uncertain significance
mshA 575779 c.432A>G synonymous_variant 0.21 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575782 c.435G>C synonymous_variant 0.2 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575812 c.465C>T synonymous_variant 0.15 ethionamide Uncertain significance
isoniazid Uncertain significance
ccsA 620346 c.456C>G synonymous_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620362 p.Ala158Thr missense_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620367 c.477T>C synonymous_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620373 c.483C>G synonymous_variant 0.19 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620376 c.486G>C synonymous_variant 0.18 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620385 c.495G>C synonymous_variant 0.18 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620388 c.498A>G synonymous_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620389 c.499C>T synonymous_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620412 c.522T>C synonymous_variant 0.17 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620415 c.525T>C synonymous_variant 0.16 amikacin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620424 c.534G>C synonymous_variant 0.18 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
ccsA 620433 c.543C>G synonymous_variant 0.17 amikacin Not assoc w R - Interim
capreomycin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
hadA 731732 c.-198G>A upstream_gene_variant 0.15 isoniazid Uncertain significance
hadA 731747 c.-183T>C upstream_gene_variant 0.14 isoniazid Uncertain significance
rpoB 760235 c.429T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 760307 c.501T>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760310 c.504G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760328 c.522G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoB 760331 c.525G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 760340 c.534G>T synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 760361 c.555T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760370 c.564C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760376 p.Asp190Glu missense_variant 0.15 rifampicin Uncertain significance
rpoB 760380 p.Thr192Leu missense_variant 0.15 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 0.13 rifampicin Uncertain significance
rpoB 760475 c.669A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760522 p.Ser239Asn missense_variant 0.16 rifampicin Uncertain significance
rpoB 760541 c.735G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 760547 c.741G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 760563 p.Arg253Met missense_variant 0.15 rifampicin Uncertain significance
rpoB 760591 p.Val262Ala missense_variant 0.15 rifampicin Uncertain significance
rpoB 760718 c.912C>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 760724 c.918T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761006 c.1200C>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 761015 c.1209G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761021 c.1215G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 761027 c.1221A>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761102 c.1296A>G synonymous_variant 0.2 rifampicin Uncertain significance
rpoB 761129 c.1323G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761132 c.1326G>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761133 c.1327T>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 761150 c.1344A>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoB 761165 c.1359G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoB 761207 c.1401C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoB 761213 c.1407G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 761219 c.1413G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoB 761477 c.1671C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 761510 c.1704T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoB 761570 c.1764T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 761588 c.1782C>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 761765 c.1959T>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoB 761772 p.His656Ala missense_variant 0.15 rifampicin Uncertain significance
rpoB 761778 p.Asn658Asp missense_variant 0.15 rifampicin Uncertain significance
rpoB 761791 p.Arg662His missense_variant 0.14 rifampicin Uncertain significance
rpoB 762083 c.2277T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoB 762317 c.2511A>G synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoB 762329 c.2523G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 762989 c.-381G>C upstream_gene_variant 0.17 rifampicin Uncertain significance
rpoB 762995 c.3189G>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763013 c.-357C>G upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoC 763025 c.-345C>T upstream_gene_variant 0.2 rifampicin Uncertain significance
rpoB 763028 c.3222T>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoB 763070 c.3264T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 763085 c.3279C>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoB 763136 c.3330C>T synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 763148 c.-222G>C upstream_gene_variant 0.14 rifampicin Uncertain significance
rpoC 763402 c.33C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 763411 c.42T>G synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 763414 c.45T>C synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 763441 c.72C>T synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 763444 c.75T>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763456 c.87A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>G synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 763528 c.159G>A synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 763573 c.204G>C synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 763603 c.234C>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763636 c.267T>C synonymous_variant 0.24 rifampicin Uncertain significance
rpoC 763660 c.291T>G synonymous_variant 0.23 rifampicin Not assoc w R - Interim
rpoC 763675 c.306C>G synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 763696 c.327T>C synonymous_variant 0.22 rifampicin Not assoc w R - Interim
rpoC 763702 c.333C>G synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763717 c.348T>C synonymous_variant 0.2 rifampicin Not assoc w R - Interim
rpoC 763723 c.354G>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 763732 c.363C>G synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 763741 c.372C>T synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 763744 c.375G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 763765 c.396T>C synonymous_variant 0.2 rifampicin Uncertain significance
rpoC 763774 c.405G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 763807 c.438T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 763816 c.447C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 764257 c.888G>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 764266 c.897T>C synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 764338 c.969G>A synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764353 c.984G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 764365 c.996C>T synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764405 c.1036A>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764419 c.1050C>G synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 764428 c.1059G>C synonymous_variant 0.18 rifampicin Not assoc w R - Interim
rpoC 764431 c.1062G>C synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 0.19 rifampicin Not assoc w R - Interim
rpoC 764446 c.1077T>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 764449 c.1080G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 764452 c.1083T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 764458 c.1089G>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764461 c.1092A>G synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 764489 c.1120C>T synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 764593 c.1224C>T synonymous_variant 0.13 rifampicin Uncertain significance
rpoC 764651 p.Ser428Thr missense_variant 0.13 rifampicin Uncertain significance
rpoC 764932 c.1563C>A synonymous_variant 0.15 rifampicin Not assoc w R - Interim
rpoC 764935 c.1566T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 765319 c.1950A>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 765327 p.His653Pro missense_variant 0.13 rifampicin Uncertain significance
rpoC 765329 p.Ser654Gly missense_variant 0.14 rifampicin Uncertain significance
rpoC 765383 p.Met672Leu missense_variant 0.15 rifampicin Uncertain significance
rpoC 765404 p.Leu679Val missense_variant 0.15 rifampicin Uncertain significance
rpoC 765937 c.2568T>C synonymous_variant 0.16 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>G synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 765994 c.2625A>T synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 766021 c.2652G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 766027 c.2658G>C synonymous_variant 0.19 rifampicin Uncertain significance
rpoC 766043 p.Gln892Glu missense_variant 0.17 rifampicin Uncertain significance
rpoC 766054 c.2685C>G synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 766597 c.3228C>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoC 766607 p.Ile1080Leu missense_variant 0.15 rifampicin Uncertain significance
rpoC 766630 c.3261G>C synonymous_variant 0.16 rifampicin Uncertain significance
rpoC 766726 c.3357T>C synonymous_variant 0.14 rifampicin Uncertain significance
rpoC 766738 c.3369G>C synonymous_variant 0.17 rifampicin Uncertain significance
rpoC 766774 c.3405T>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 766801 c.3432C>G synonymous_variant 0.18 rifampicin Uncertain significance
rpoC 766804 c.3435A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 766861 c.3492G>C synonymous_variant 0.21 rifampicin Not assoc w R - Interim
rpoC 766864 c.3495G>C synonymous_variant 0.21 rifampicin Uncertain significance
rpoC 767059 c.3690T>G synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 767062 c.3693C>A synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 767098 c.3729T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoC 767119 c.3750A>G synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 767134 c.3765C>A synonymous_variant 0.15 rifampicin Uncertain significance
rpoC 767158 c.3789T>C synonymous_variant 0.17 rifampicin Not assoc w R - Interim
rpoC 767180 p.Ala1271Gln missense_variant 0.15 rifampicin Uncertain significance
mmpL5 775639 p.Ile948Val missense_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
rpsL 781395 c.-165T>C upstream_gene_variant 1.0 streptomycin Not assoc w R
rpsL 781700 c.141G>C synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781703 c.144G>T synonymous_variant 0.13 streptomycin Uncertain significance
rpsL 781715 c.156T>C synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781728 c.169T>C synonymous_variant 0.16 streptomycin Uncertain significance
rpsL 781736 c.177T>C synonymous_variant 0.13 streptomycin Uncertain significance
rpsL 781742 c.183C>T synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781748 c.189C>G synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781808 c.249C>T synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781811 c.252C>T synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781832 c.273T>C synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781838 c.279G>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781841 c.282C>G synonymous_variant 0.17 streptomycin Uncertain significance
rpsL 781865 c.306G>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781868 c.309T>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781871 c.312G>C synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781877 c.318T>C synonymous_variant 0.14 streptomycin Uncertain significance
rpsL 781898 c.339A>T synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781916 c.357T>C synonymous_variant 0.15 streptomycin Uncertain significance
rpsL 781929 p.Gly124Ser missense_variant 0.17 streptomycin Uncertain significance
rplC 800204 c.-605T>C upstream_gene_variant 0.95 linezolid Uncertain significance
rplC 800582 c.-227C>G upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800612 c.-197A>G upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800618 c.-191T>C upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800648 c.-161A>T upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800654 c.-155T>C upstream_gene_variant 0.15 linezolid Uncertain significance
rplC 800693 c.-116A>G upstream_gene_variant 0.18 linezolid Uncertain significance
rplC 800703 c.-106T>C upstream_gene_variant 0.16 linezolid Uncertain significance
rplC 800715 c.-94A>C upstream_gene_variant 0.15 linezolid Uncertain significance
rplC 800720 c.-89T>C upstream_gene_variant 0.16 linezolid Uncertain significance
rplC 800723 c.-86C>G upstream_gene_variant 0.16 linezolid Uncertain significance
rplC 800747 c.-62C>G upstream_gene_variant 0.14 linezolid Uncertain significance
rplC 800814 c.6A>G synonymous_variant 0.14 linezolid Uncertain significance
rplC 800817 c.9A>T synonymous_variant 0.14 linezolid Uncertain significance
rplC 800907 c.99C>G synonymous_variant 0.14 linezolid Uncertain significance
Rv1129c 1254624 c.-90G>A upstream_gene_variant 0.96 isoniazid Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
fbiC 1303818 c.888C>G synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303836 c.906G>C synonymous_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303845 c.915C>G synonymous_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303846 p.Phe306Val missense_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303854 c.924T>C synonymous_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303860 c.930A>C synonymous_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303884 c.954T>G synonymous_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303905 c.975G>C synonymous_variant 0.2 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303914 c.984C>G synonymous_variant 0.22 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303980 c.1050G>A synonymous_variant 0.2 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1303998 c.1068T>G synonymous_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304004 c.1074A>G synonymous_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304008 c.1078T>C synonymous_variant 0.21 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304022 c.1092T>C synonymous_variant 0.16 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304031 c.1101C>G synonymous_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304034 c.1104A>G synonymous_variant 0.18 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304040 c.1110C>G synonymous_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304046 c.1116C>G synonymous_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304049 c.1119T>C synonymous_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304050 c.1120T>C synonymous_variant 0.17 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304097 c.1167G>C synonymous_variant 0.19 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304646 c.1716T>C synonymous_variant 0.14 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304661 c.1731C>T synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304703 c.1773C>G synonymous_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
fbiC 1304893 p.Gly655Ser missense_variant 0.13 clofazimine Uncertain significance
delamanid Uncertain significance
pretomanid Uncertain significance
rrs 1471659 n.-187C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
rrl 1475006 n.1349A>T non_coding_transcript_exon_variant 0.13 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475013 n.1356G>A non_coding_transcript_exon_variant 0.13 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.14 capreomycin Uncertain significance
linezolid Uncertain significance
rpsA 1833661 c.120A>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833667 c.126C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833721 c.180A>G synonymous_variant 0.18 pyrazinamide Uncertain significance
rpsA 1833724 c.183C>G synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833727 c.186G>C synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833742 c.201A>G synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1833745 c.204G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1833748 c.207C>G synonymous_variant 0.16 pyrazinamide Uncertain significance
rpsA 1833847 c.306C>G synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1833874 c.333T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833886 c.345C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1833928 c.387G>C synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833940 c.399C>G synonymous_variant 0.19 pyrazinamide Uncertain significance
rpsA 1833971 c.430C>T synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1833979 c.438T>C synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834000 c.459G>C synonymous_variant 0.13 pyrazinamide Uncertain significance
rpsA 1834081 c.540C>T synonymous_variant 0.17 pyrazinamide Uncertain significance
rpsA 1834105 c.564C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834108 c.567C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834123 c.582C>G synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834451 c.910T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
rpsA 1834465 c.924T>C synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834468 c.927A>G synonymous_variant 0.14 pyrazinamide Uncertain significance
rpsA 1834489 c.948T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
tsnR 1854300 p.Leu232Pro missense_variant 1.0 linezolid Not assoc w R
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
bacA 2063685 c.1044G>A synonymous_variant 0.91 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
bacA 2063911 p.Ile273Thr missense_variant 0.93 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Uncertain significance
streptomycin Uncertain significance
bacA 2064979 c.-251C>T upstream_gene_variant 0.13 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
bacA 2064984 c.-256A>G upstream_gene_variant 0.14 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
bacA 2064993 c.-265T>C upstream_gene_variant 0.16 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance
streptomycin Uncertain significance
PPE35 2167033 c.347_*615del frameshift_variant&stop_lost&splice_region_variant 0.96 pyrazinamide Uncertain significance
PPE35 2170308 p.Leu102Ala missense_variant 0.9 pyrazinamide Uncertain significance
PPE35 2170313 c.300G>C synonymous_variant 0.91 pyrazinamide Not assoc w R - Interim
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0 bedaquiline Not assoc w R - Interim
clofazimine Not assoc w R
kasA 2517989 c.-126T>C upstream_gene_variant 0.14 isoniazid Uncertain significance
kasA 2517993 c.-122G>T upstream_gene_variant 0.14 isoniazid Uncertain significance
kasA 2518789 c.675G>C synonymous_variant 0.14 isoniazid Uncertain significance
kasA 2518792 c.678C>A synonymous_variant 0.14 isoniazid Uncertain significance
kasA 2518795 c.681C>G synonymous_variant 0.14 isoniazid Uncertain significance
kasA 2519137 c.1023T>G synonymous_variant 0.14 isoniazid Uncertain significance
kasA 2519158 c.1044C>T synonymous_variant 0.14 isoniazid Uncertain significance
kasA 2519173 c.1059C>G synonymous_variant 0.14 isoniazid Uncertain significance
ahpC 2726591 c.399C>G synonymous_variant 0.13 isoniazid Uncertain significance
ahpC 2726593 p.Val134Ala missense_variant 0.13 isoniazid Uncertain significance
ahpC 2726638 p.Ala149Val missense_variant 0.13 isoniazid Uncertain significance
folC 2746308 p.Arg431Ser missense_variant 0.13 para-aminosalicylic_acid Uncertain significance
Rv2477c 2783140 c.903C>G synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783146 c.897G>A synonymous_variant 0.17 amikacin Not assoc w R - Interim
ethambutol Uncertain significance
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783149 c.894G>C synonymous_variant 0.17 amikacin Not assoc w R - Interim
ethambutol Uncertain significance
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Uncertain significance
Rv2477c 2783158 c.885A>C synonymous_variant 0.16 amikacin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Uncertain significance
Rv2477c 2783182 c.861C>G synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783185 c.858G>A synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783194 c.849A>G synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783221 c.822G>C synonymous_variant 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783224 c.819C>G synonymous_variant 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783230 c.813T>G synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Not assoc w R - Interim
kanamycin Uncertain significance
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
Rv2477c 2783235 c.808T>C synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783254 c.789A>G synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783263 c.780G>C synonymous_variant 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783485 c.558G>C synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783497 c.544_546delTTGinsCTC synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783502 c.541T>C synonymous_variant 0.15 amikacin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
Rv2477c 2783520 c.523T>C synonymous_variant 0.14 amikacin Uncertain significance
ethambutol Not assoc w R - Interim
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Not assoc w R - Interim
streptomycin Uncertain significance
Rv2477c 2783521 c.522G>C synonymous_variant 0.14 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783527 c.516A>G synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783563 c.480A>G synonymous_variant 0.2 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783656 c.387G>C synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783665 c.378A>G synonymous_variant 0.17 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783674 c.369T>C synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783683 c.360A>G synonymous_variant 0.21 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783700 p.Thr115Ser missense_variant 0.25 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783718 c.325T>C synonymous_variant 0.27 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783719 c.324A>G synonymous_variant 0.27 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783751 p.Ile98Val missense_variant 0.2 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783758 p.Asp95Glu missense_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783761 c.282G>C synonymous_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783766 p.Met93Leu missense_variant 0.18 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783797 p.Asp82Glu missense_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783815 c.228A>G synonymous_variant 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783883 c.160T>C synonymous_variant 0.15 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783884 c.159T>C synonymous_variant 0.16 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783887 c.156C>G synonymous_variant 0.16 amikacin Not assoc w R - Interim
ethambutol Not assoc w R - Interim
kanamycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
Rv2477c 2783914 c.129T>C synonymous_variant 0.19 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783920 c.123G>C synonymous_variant 0.23 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
Rv2477c 2783929 c.114C>G synonymous_variant 0.2 amikacin Uncertain significance
ethambutol Uncertain significance
kanamycin Uncertain significance
levofloxacin Uncertain significance
moxifloxacin Uncertain significance
rifampicin Uncertain significance
streptomycin Uncertain significance
ribD 2986910 c.72C>A synonymous_variant 1.0 para-aminosalicylic_acid Uncertain significance
thyX 3067439 c.507A>G synonymous_variant 0.32 para-aminosalicylic_acid Uncertain significance
thyX 3067445 c.501C>G synonymous_variant 0.34 para-aminosalicylic_acid Uncertain significance
thyX 3067457 c.489C>G synonymous_variant 0.38 para-aminosalicylic_acid Uncertain significance
thyX 3067465 p.Ile161Val missense_variant 0.41 para-aminosalicylic_acid Uncertain significance
thyX 3067475 c.471A>G synonymous_variant 0.38 para-aminosalicylic_acid Uncertain significance
thyX 3067490 c.456C>G synonymous_variant 0.42 para-aminosalicylic_acid Uncertain significance
thyX 3067493 c.453A>G synonymous_variant 0.44 para-aminosalicylic_acid Uncertain significance
thyX 3067515 p.Ser144Thr missense_variant 0.33 para-aminosalicylic_acid Uncertain significance
thyX 3067530 p.Ala139Ser missense_variant 0.29 para-aminosalicylic_acid Uncertain significance
thyX 3067545 p.Glu134Ala missense_variant 0.3 para-aminosalicylic_acid Uncertain significance
thyX 3067549 p.Thr133Ala missense_variant 0.27 para-aminosalicylic_acid Uncertain significance
thyX 3067556 p.His130Gln missense_variant 0.27 para-aminosalicylic_acid Uncertain significance
thyX 3067559 c.387C>G synonymous_variant 0.26 para-aminosalicylic_acid Uncertain significance
thyX 3067565 p.Asp127Glu missense_variant 0.24 para-aminosalicylic_acid Uncertain significance
thyX 3067577 c.369G>A synonymous_variant 0.21 para-aminosalicylic_acid Uncertain significance
thyX 3067652 c.294T>C synonymous_variant 0.18 para-aminosalicylic_acid Uncertain significance
thyX 3067661 c.285C>G synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067685 c.261A>C synonymous_variant 0.19 para-aminosalicylic_acid Uncertain significance
thyX 3067691 p.Ile85Leu missense_variant 0.16 para-aminosalicylic_acid Uncertain significance
thyX 3067772 c.174C>G synonymous_variant 0.14 para-aminosalicylic_acid Uncertain significance
thyX 3067781 c.165C>A synonymous_variant 0.15 para-aminosalicylic_acid Uncertain significance
thyX 3067793 c.153T>C synonymous_variant 0.13 para-aminosalicylic_acid Uncertain significance
thyX 3067799 c.147G>A synonymous_variant 0.15 para-aminosalicylic_acid Uncertain significance
thyX 3067802 c.144C>G synonymous_variant 0.18 para-aminosalicylic_acid Uncertain significance
thyX 3067814 c.132T>C synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067850 c.96A>C synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067869 p.Thr26Ser missense_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067874 c.72C>G synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067883 c.63C>G synonymous_variant 0.16 para-aminosalicylic_acid Uncertain significance
thyX 3067886 c.60A>C synonymous_variant 0.17 para-aminosalicylic_acid Uncertain significance
thyX 3067889 c.57C>G synonymous_variant 0.15 para-aminosalicylic_acid Uncertain significance
thyX 3067898 p.Asp16Glu missense_variant 0.15 para-aminosalicylic_acid Uncertain significance
thyA 3073953 c.519T>C synonymous_variant 0.14 para-aminosalicylic_acid Uncertain significance
ald 3086742 c.-78A>C upstream_gene_variant 0.91 cycloserine Uncertain significance
ald 3086788 c.-32T>C upstream_gene_variant 1.0 cycloserine Uncertain significance
lpqB 3623721 p.Ser397Thr missense_variant 0.14 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625065 p.Met517Leu missense_variant 1.0 bedaquiline Uncertain significance
rifampicin Not assoc w R
mtrB 3625569 c.1045T>C synonymous_variant 0.18 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625572 p.Thr348Ser missense_variant 0.17 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625579 c.-669A>G upstream_gene_variant 0.18 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625594 c.-684T>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625602 c.-692T>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625612 c.-702G>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625616 p.Arg333Ala missense_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625624 c.-714C>G upstream_gene_variant 0.21 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625636 c.978C>G synonymous_variant 0.23 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625656 c.958T>C synonymous_variant 0.23 bedaquiline Not assoc w R - Interim
rifampicin Not assoc w R - Interim
lpqB 3625663 c.-753G>C upstream_gene_variant 0.2 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625669 c.-759G>C upstream_gene_variant 0.19 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625687 c.-777G>C upstream_gene_variant 0.14 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625690 c.-780T>C upstream_gene_variant 0.14 bedaquiline Uncertain significance
rifampicin Uncertain significance
lpqB 3625696 c.-786A>G upstream_gene_variant 0.14 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625705 c.909C>G synonymous_variant 0.15 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625714 c.-804C>T upstream_gene_variant 0.14 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625720 c.894G>C synonymous_variant 0.14 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
mtrB 3625729 c.885A>G synonymous_variant 0.14 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
lpqB 3625735 c.-825C>T upstream_gene_variant 0.14 bedaquiline Uncertain significance
rifampicin Uncertain significance
mtrB 3625765 c.849C>G synonymous_variant 0.13 bedaquiline Uncertain significance
rifampicin Not assoc w R - Interim
rpoA 3877743 c.765T>C synonymous_variant 0.14 rifampicin Not assoc w R - Interim
rpoA 3877782 c.726T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoA 3877791 c.717C>G synonymous_variant 0.14 rifampicin Uncertain significance
rpoA 3878001 c.507A>G synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoA 3878022 c.486T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3878028 c.480G>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3878031 c.477T>C synonymous_variant 0.15 rifampicin Uncertain significance
rpoA 3878040 c.468T>C synonymous_variant 0.13 rifampicin Not assoc w R - Interim
rpoA 3878043 c.465G>A synonymous_variant 0.13 rifampicin Uncertain significance
clpC1 4039103 c.1602T>C synonymous_variant 0.13 pyrazinamide Uncertain significance
clpC1 4039112 c.1593C>G synonymous_variant 0.14 pyrazinamide Uncertain significance
clpC1 4039121 c.1584T>C synonymous_variant 0.15 pyrazinamide Uncertain significance
clpC1 4039142 c.1563A>G synonymous_variant 0.16 pyrazinamide Uncertain significance
clpC1 4039145 c.1560G>C synonymous_variant 0.16 pyrazinamide Uncertain significance
panD 4044788 c.-507G>C upstream_gene_variant 0.15 pyrazinamide Uncertain significance
panD 4044791 c.-510G>C upstream_gene_variant 0.15 pyrazinamide Uncertain significance
panD 4044800 c.-519C>G upstream_gene_variant 0.15 pyrazinamide Uncertain significance
panD 4044812 c.-531A>C upstream_gene_variant 0.15 pyrazinamide Uncertain significance
panD 4044818 c.-538_-537delCGinsAC upstream_gene_variant 0.16 pyrazinamide Uncertain significance
panD 4044823 c.-542G>C upstream_gene_variant 0.15 pyrazinamide Uncertain significance
panD 4044844 c.-563T>C upstream_gene_variant 0.16 pyrazinamide Uncertain significance
embC 4242643 c.2781C>T synonymous_variant 1.0 ethambutol Not assoc w R
embA 4245189 c.1957C>T synonymous_variant 0.13 ethambutol Uncertain significance
embB 4247464 c.951C>G synonymous_variant 0.14 ethambutol Uncertain significance
embB 4247470 c.957T>C synonymous_variant 0.15 ethambutol Uncertain significance
embB 4247491 c.978G>C synonymous_variant 0.17 ethambutol Uncertain significance
embB 4247497 c.984T>C synonymous_variant 0.17 ethambutol Uncertain significance
embB 4247512 c.999T>C synonymous_variant 0.15 ethambutol Uncertain significance
embB 4249594 c.3081G>A synonymous_variant 0.97 ethambutol Not assoc w R - Interim
ethA 4328376 c.-903G>C upstream_gene_variant 0.96 ethionamide Uncertain significance
whiB6 4338595 c.-75delG upstream_gene_variant 1.0 amikacin Not assoc w R
capreomycin Not assoc w R
kanamycin Not assoc w R
whiB6 4338732 c.-211C>T upstream_gene_variant 1.0 amikacin Uncertain significance
capreomycin Uncertain significance
kanamycin Uncertain significance