TB-Profiler result

Run: ERR2228810
Summary

Run ID: ERR2228810

Sample name:

Date: 31-03-2023 16:21:38

Number of reads: 389023

Percentage reads mapped: 31.69

Strain: lineage4

Drug-resistance: RR-TB

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761089 p.Ser428Thr missense_variant 0.29 rifampicin
rpoB 761127 p.Ser441Ala missense_variant 0.22 rifampicin
rrs 1472733 n.888G>A non_coding_transcript_exon_variant 0.36 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.78 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.76 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5345 p.Ser36Pro missense_variant 0.18
gyrB 6422 p.Trp395Arg missense_variant 0.5
gyrB 7084 p.Glu615Asp missense_variant 0.4
gyrA 7300 c.-2A>T upstream_gene_variant 0.38
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7571 c.270G>T synonymous_variant 0.33
gyrA 8445 p.Arg382Cys missense_variant 0.2
gyrA 9159 c.1862delC frameshift_variant 0.29
gyrA 9631 p.Val777Asp missense_variant 0.4
mshA 575293 c.-55T>G upstream_gene_variant 0.22
mshA 576414 p.Gly356Val missense_variant 0.4
mshA 576462 p.Ala372Glu missense_variant 0.4
rpoB 759641 c.-166T>G upstream_gene_variant 0.29
rpoB 759666 c.-141T>C upstream_gene_variant 0.33
rpoB 761084 c.1278C>A synonymous_variant 0.29
rpoB 761097 c.1291_1293delAGCinsTCG synonymous_variant 0.33
rpoB 761102 c.1296A>G synonymous_variant 0.4
rpoB 761111 c.1305C>T synonymous_variant 0.29
rpoB 761231 c.1425C>T synonymous_variant 0.25
rpoB 761234 c.1428G>T synonymous_variant 0.25
rpoB 761246 c.1440C>T synonymous_variant 0.25
rpoB 761249 c.1443A>G synonymous_variant 0.29
rpoB 761422 p.Asn539Ile missense_variant 0.33
rpoB 761516 c.1710G>T synonymous_variant 0.29
rpoB 762233 c.2427G>C synonymous_variant 0.29
rpoB 762236 c.2430G>T synonymous_variant 0.25
rpoB 762245 c.2439G>T synonymous_variant 0.27
rpoB 762254 c.2448T>C synonymous_variant 0.27
rpoB 762257 c.2451C>G synonymous_variant 0.27
rpoB 762284 c.2478G>C synonymous_variant 0.14
rpoB 762878 p.Ile1024Met missense_variant 0.31
rpoB 762879 p.Met1025Leu missense_variant 0.29
rpoC 762899 c.-471G>T upstream_gene_variant 0.59
rpoC 762920 c.-450C>T upstream_gene_variant 0.67
rpoC 762929 c.-441G>C upstream_gene_variant 0.57
rpoC 762959 c.-411G>T upstream_gene_variant 0.38
rpoC 762971 c.-399G>C upstream_gene_variant 0.39
rpoC 762983 c.-387C>T upstream_gene_variant 0.27
rpoC 762989 c.-381G>A upstream_gene_variant 0.23
rpoC 762995 c.-375G>T upstream_gene_variant 0.27
rpoB 763090 p.Lys1095Met missense_variant 0.33
rpoC 763340 c.-30T>A upstream_gene_variant 0.22
rpoC 763528 c.159G>A synonymous_variant 0.5
rpoC 763534 c.165T>C synonymous_variant 0.56
rpoC 763537 c.168C>G synonymous_variant 0.58
rpoC 763546 c.177A>G synonymous_variant 0.62
rpoC 763570 c.201G>C synonymous_variant 0.65
rpoC 763573 c.204G>C synonymous_variant 0.62
rpoC 763594 c.225C>T synonymous_variant 0.62
rpoC 763622 p.Ala85Ser missense_variant 0.59
rpoC 763627 p.Lys86Asn missense_variant 0.62
rpoC 763642 c.273G>T synonymous_variant 0.57
rpoC 763648 c.279C>A synonymous_variant 0.5
rpoC 763651 c.282C>T synonymous_variant 0.45
rpoC 763654 c.285C>T synonymous_variant 0.45
rpoC 763682 p.Trp105Arg missense_variant 0.29
rpoC 763805 p.Asn146Asp missense_variant 0.17
rpoC 765619 p.Glu750Asp missense_variant 0.25
rpoC 766240 c.2871T>A synonymous_variant 0.25
rpoC 766377 p.Ile1003Thr missense_variant 0.17
rpoC 766981 c.3612T>G synonymous_variant 0.29
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776392 p.Asp697Asn missense_variant 0.29
mmpL5 776671 p.Phe604Val missense_variant 0.22
mmpL5 777195 p.Glu429Val missense_variant 0.25
mmpL5 777340 p.Lys381* stop_gained 0.22
mmpL5 777354 p.Val376Gly missense_variant 0.25
mmpL5 778078 p.Thr135Pro missense_variant 0.25
mmpR5 779077 p.Arg30Trp missense_variant 0.5
mmpR5 779189 p.Ile67Ser missense_variant 0.25
mmpS5 779606 c.-701C>A upstream_gene_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781655 c.96T>C synonymous_variant 0.25
rpsL 781658 c.99A>G synonymous_variant 0.27
rpsL 781679 c.120C>G synonymous_variant 0.25
rpsL 781682 c.123T>G synonymous_variant 0.27
rpsL 781755 p.Tyr66Asp missense_variant 0.2
fbiC 1303250 p.Phe107Ser missense_variant 0.21
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1303880 p.Thr317Lys missense_variant 0.22
fbiC 1304050 p.Leu374Val missense_variant 0.25
atpE 1460995 c.-50A>T upstream_gene_variant 0.4
rrs 1471878 n.33C>T non_coding_transcript_exon_variant 0.29
rrs 1471896 n.51T>C non_coding_transcript_exon_variant 0.29
rrs 1471900 n.55C>T non_coding_transcript_exon_variant 0.29
rrs 1472085 n.240C>T non_coding_transcript_exon_variant 0.37
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.45
rrs 1472107 n.262A>G non_coding_transcript_exon_variant 0.48
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.43
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.52
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 0.52
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 0.5
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 0.48
rrs 1472137 n.292G>A non_coding_transcript_exon_variant 0.22
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.71
rrs 1472151 n.306C>T non_coding_transcript_exon_variant 0.28
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 0.45
rrs 1472164 n.319G>A non_coding_transcript_exon_variant 0.29
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.31
rrs 1472177 n.332C>T non_coding_transcript_exon_variant 0.33
rrs 1472203 n.358G>A non_coding_transcript_exon_variant 0.31
rrs 1472210 n.365A>C non_coding_transcript_exon_variant 0.3
rrs 1472213 n.368G>C non_coding_transcript_exon_variant 0.27
rrs 1472215 n.370A>G non_coding_transcript_exon_variant 0.28
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.72
rrs 1472234 n.389T>C non_coding_transcript_exon_variant 0.15
rrs 1472236 n.391C>G non_coding_transcript_exon_variant 0.15
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.75
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 0.7
rrs 1472279 n.434T>G non_coding_transcript_exon_variant 0.5
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.5
rrs 1472368 n.523A>G non_coding_transcript_exon_variant 0.7
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.78
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.78
rrs 1472412 n.567A>G non_coding_transcript_exon_variant 0.75
rrs 1472498 n.653C>T non_coding_transcript_exon_variant 0.33
rrs 1472507 n.662C>A non_coding_transcript_exon_variant 0.7
rrs 1472517 n.672T>A non_coding_transcript_exon_variant 0.18
rrs 1472518 n.673G>T non_coding_transcript_exon_variant 0.18
rrs 1472522 n.677T>G non_coding_transcript_exon_variant 0.5
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.22
rrs 1472541 n.696T>G non_coding_transcript_exon_variant 0.13
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.85
rrs 1472570 n.725G>A non_coding_transcript_exon_variant 0.21
rrs 1472571 n.726G>C non_coding_transcript_exon_variant 0.62
rrs 1472571 n.726G>T non_coding_transcript_exon_variant 0.84
rrs 1472573 n.728C>T non_coding_transcript_exon_variant 0.2
rrs 1472579 n.734G>T non_coding_transcript_exon_variant 0.23
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.91
rrs 1472582 n.737G>T non_coding_transcript_exon_variant 0.59
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.63
rrs 1472585 n.740A>C non_coding_transcript_exon_variant 0.63
rrs 1472596 n.751G>T non_coding_transcript_exon_variant 0.24
rrs 1472598 n.753A>T non_coding_transcript_exon_variant 0.25
rrs 1472614 n.769G>T non_coding_transcript_exon_variant 0.26
rrs 1472616 n.771G>A non_coding_transcript_exon_variant 0.25
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.62
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.74
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.84
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.81
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.9
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.84
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.87
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.84
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.68
rrs 1472713 n.868T>C non_coding_transcript_exon_variant 0.18
rrs 1472716 n.871C>T non_coding_transcript_exon_variant 0.2
rrs 1472742 n.897C>T non_coding_transcript_exon_variant 0.34
rrs 1472744 n.899A>G non_coding_transcript_exon_variant 0.39
rrs 1472767 n.922G>A non_coding_transcript_exon_variant 0.86
rrs 1472767 n.922G>C non_coding_transcript_exon_variant 0.83
rrs 1472781 n.936C>T non_coding_transcript_exon_variant 0.53
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.42
rrs 1472793 n.948A>T non_coding_transcript_exon_variant 0.42
rrs 1472803 n.958T>A non_coding_transcript_exon_variant 0.38
rrs 1472812 n.967A>T non_coding_transcript_exon_variant 0.47
rrs 1472880 n.1035_1036insA non_coding_transcript_exon_variant 0.25
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.38
rrs 1472954 n.1110delC non_coding_transcript_exon_variant 0.91
rrs 1472958 n.1113_1114insC non_coding_transcript_exon_variant 0.89
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.93
rrs 1472986 n.1141_1142insA non_coding_transcript_exon_variant 0.91
rrs 1472989 n.1145delA non_coding_transcript_exon_variant 0.92
rrs 1472996 n.1151T>C non_coding_transcript_exon_variant 0.93
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.77
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.5
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.3
rrs 1473091 n.1246G>A non_coding_transcript_exon_variant 0.22
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.22
rrs 1473094 n.1249T>G non_coding_transcript_exon_variant 0.25
rrs 1473099 n.1254T>G non_coding_transcript_exon_variant 0.25
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 0.25
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.25
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.25
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 0.25
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.25
rrs 1473120 n.1275C>T non_coding_transcript_exon_variant 0.25
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.25
rrs 1473122 n.1277T>G non_coding_transcript_exon_variant 0.29
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.33
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.71
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.73
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.78
rrs 1473177 n.1332G>A non_coding_transcript_exon_variant 0.17
rrs 1473226 n.1381C>G non_coding_transcript_exon_variant 0.93
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.88
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.9
rrs 1473288 n.1443C>G non_coding_transcript_exon_variant 0.76
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.69
rrs 1473292 n.1447G>T non_coding_transcript_exon_variant 0.73
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.79
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.75
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.69
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.69
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.67
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.79
rrl 1473839 n.182G>T non_coding_transcript_exon_variant 0.5
rrl 1473862 n.205C>T non_coding_transcript_exon_variant 0.29
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.3
rrl 1473887 n.230T>G non_coding_transcript_exon_variant 0.38
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.29
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.33
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1474166 n.509G>T non_coding_transcript_exon_variant 0.4
rrl 1474167 n.510T>C non_coding_transcript_exon_variant 0.4
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.5
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.55
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.67
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 0.69
rrl 1474218 n.561T>G non_coding_transcript_exon_variant 0.67
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.42
rrl 1474283 n.626A>C non_coding_transcript_exon_variant 0.43
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.25
rrl 1474467 n.810A>T non_coding_transcript_exon_variant 0.36
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.36
rrl 1474488 n.831G>A non_coding_transcript_exon_variant 0.4
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.38
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.38
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.39
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.39
rrl 1474516 n.859C>T non_coding_transcript_exon_variant 0.42
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.33
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.27
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.31
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.31
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.44
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.48
rrl 1474582 n.925T>A non_coding_transcript_exon_variant 0.69
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.42
rrl 1474752 n.1096delA non_coding_transcript_exon_variant 0.5
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.44
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.36
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.36
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.4
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.4
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.4
rrl 1474799 n.1143delT non_coding_transcript_exon_variant 0.44
rrl 1474803 n.1146_1147insA non_coding_transcript_exon_variant 0.4
rrl 1474806 n.1149A>C non_coding_transcript_exon_variant 0.45
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.69
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.69
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.69
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.62
rrl 1474853 n.1196A>G non_coding_transcript_exon_variant 0.79
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.82
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.79
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.77
rrl 1475171 n.1514C>T non_coding_transcript_exon_variant 0.22
rrl 1475175 n.1518G>C non_coding_transcript_exon_variant 0.2
rrl 1475574 n.1917C>A non_coding_transcript_exon_variant 0.33
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 0.3
rrl 1475713 n.2056C>G non_coding_transcript_exon_variant 0.44
rrl 1475716 n.2059A>G non_coding_transcript_exon_variant 0.44
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 0.25
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 0.4
rrl 1475803 n.2146T>C non_coding_transcript_exon_variant 0.44
rrl 1475804 n.2147G>C non_coding_transcript_exon_variant 0.44
rrl 1475816 n.2159C>G non_coding_transcript_exon_variant 0.32
rrl 1475817 n.2160A>G non_coding_transcript_exon_variant 0.38
rrl 1475858 n.2201T>C non_coding_transcript_exon_variant 0.16
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.76
rrl 1475877 n.2220C>T non_coding_transcript_exon_variant 0.93
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.92
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.85
rrl 1475892 n.2235A>C non_coding_transcript_exon_variant 0.92
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 1.0
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 1.0
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.91
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.88
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.86
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0
rrl 1476117 n.2460G>A non_coding_transcript_exon_variant 1.0
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 1.0
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 1.0
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 1.0
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.92
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.92
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.94
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.92
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.92
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 0.92
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 0.92
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.72
rrl 1476225 n.2568T>G non_coding_transcript_exon_variant 0.22
rrl 1476229 n.2572C>T non_coding_transcript_exon_variant 0.24
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.53
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.42
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.38
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.36
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.95
rrl 1476268 n.2611A>T non_coding_transcript_exon_variant 0.56
rrl 1476275 n.2618T>A non_coding_transcript_exon_variant 0.53
rrl 1476279 n.2622G>A non_coding_transcript_exon_variant 0.6
rrl 1476280 n.2623A>C non_coding_transcript_exon_variant 0.69
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.23
rrl 1476293 n.2636C>T non_coding_transcript_exon_variant 1.0
rrl 1476294 n.2637A>G non_coding_transcript_exon_variant 1.0
rrl 1476295 n.2638C>G non_coding_transcript_exon_variant 1.0
rrl 1476296 n.2639C>T non_coding_transcript_exon_variant 1.0
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 1.0
rrl 1476301 n.2644A>C non_coding_transcript_exon_variant 1.0
rrl 1476302 n.2645G>A non_coding_transcript_exon_variant 1.0
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 1.0
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 1.0
rrl 1476313 n.2656G>A non_coding_transcript_exon_variant 0.89
rrl 1476332 n.2675G>C non_coding_transcript_exon_variant 0.82
rrl 1476353 n.2696G>T non_coding_transcript_exon_variant 0.75
rrl 1476358 n.2701T>C non_coding_transcript_exon_variant 0.78
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.19
rrl 1476363 n.2706A>G non_coding_transcript_exon_variant 0.2
rrl 1476366 n.2709A>C non_coding_transcript_exon_variant 0.19
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.21
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.94
rrl 1476372 n.2715T>C non_coding_transcript_exon_variant 0.72
rrl 1476374 n.2717T>G non_coding_transcript_exon_variant 0.25
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.28
rrl 1476382 n.2725A>G non_coding_transcript_exon_variant 0.67
rrl 1476383 n.2726T>A non_coding_transcript_exon_variant 0.68
rrl 1476408 n.2751G>A non_coding_transcript_exon_variant 0.64
rrl 1476425 n.2768G>T non_coding_transcript_exon_variant 0.6
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.97
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 0.97
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.68
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.99
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.94
rrl 1476514 n.2857C>T non_coding_transcript_exon_variant 0.71
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.2
rrl 1476517 n.2860C>T non_coding_transcript_exon_variant 0.5
rrl 1476519 n.2862C>G non_coding_transcript_exon_variant 0.5
rrl 1476523 n.2866T>G non_coding_transcript_exon_variant 0.22
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.75
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.75
rrl 1476530 n.2873C>T non_coding_transcript_exon_variant 0.62
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.75
rrl 1476537 n.2880A>G non_coding_transcript_exon_variant 0.56
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.67
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.73
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 0.79
rrl 1476567 n.2910C>T non_coding_transcript_exon_variant 0.76
rrl 1476572 n.2915G>A non_coding_transcript_exon_variant 0.76
rrl 1476573 n.2916A>T non_coding_transcript_exon_variant 0.81
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.76
rrl 1476595 n.2938C>G non_coding_transcript_exon_variant 0.33
rrl 1476720 n.3063G>T non_coding_transcript_exon_variant 0.33
rrl 1476721 n.3064G>T non_coding_transcript_exon_variant 0.33
rpsA 1833646 p.Asp35Glu missense_variant 0.25
rpsA 1833942 p.Val134Ala missense_variant 0.25
rpsA 1833970 c.429G>C synonymous_variant 0.13
rpsA 1833979 c.438T>C synonymous_variant 0.19
rpsA 1833994 c.453G>C synonymous_variant 0.13
rpsA 1833997 c.456G>T synonymous_variant 0.19
rpsA 1834000 c.459G>T synonymous_variant 0.24
rpsA 1834012 c.471G>A synonymous_variant 0.22
rpsA 1834015 c.474G>C synonymous_variant 0.2
rpsA 1834018 c.477C>T synonymous_variant 0.2
rpsA 1834024 c.483G>C synonymous_variant 0.21
rpsA 1834034 p.Ile165Val missense_variant 0.25
rpsA 1834039 c.498C>T synonymous_variant 0.21
rpsA 1834040 p.Lys167Gln missense_variant 0.21
rpsA 1834069 c.528G>C synonymous_variant 0.29
rpsA 1834090 c.549G>T synonymous_variant 0.25
rpsA 1834099 c.558C>G synonymous_variant 0.28
rpsA 1834105 c.564C>T synonymous_variant 0.33
rpsA 1834108 c.567C>G synonymous_variant 0.33
rpsA 1834114 c.573G>C synonymous_variant 0.25
rpsA 1834189 c.648G>C synonymous_variant 0.15
rpsA 1834213 c.672G>C synonymous_variant 0.18
rpsA 1834216 c.675C>T synonymous_variant 0.27
rpsA 1834219 c.678C>T synonymous_variant 0.25
rpsA 1834222 c.681T>C synonymous_variant 0.18
rpsA 1834225 c.684C>G synonymous_variant 0.2
rpsA 1834240 c.699T>C synonymous_variant 0.22
rpsA 1834241 c.700_702delCTGinsTTA synonymous_variant 0.22
rpsA 1834246 c.705G>C synonymous_variant 0.22
rpsA 1834249 c.708T>C synonymous_variant 0.22
rpsA 1834261 c.720A>G synonymous_variant 0.25
rpsA 1834264 c.723G>C synonymous_variant 0.22
rpsA 1834273 c.732C>T synonymous_variant 0.25
rpsA 1834658 p.Phe373Val missense_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918607 p.Val223Gly missense_variant 0.33
ndh 2101703 p.Glu447Val missense_variant 0.33
ndh 2101898 p.Ile382Ser missense_variant 1.0
ndh 2102652 p.Phe131Ile missense_variant 0.29
katG 2154427 p.Asn562Thr missense_variant 0.4
katG 2155549 p.Val188Gly missense_variant 0.5
katG 2156127 c.-16T>A upstream_gene_variant 0.4
katG 2156152 c.-41G>T upstream_gene_variant 0.2
katG 2156378 c.-267T>C upstream_gene_variant 0.22
PPE35 2167779 p.Asn945Thr missense_variant 0.29
PPE35 2168619 p.Leu665* stop_gained 0.25
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169258 p.Gln452Leu missense_variant 0.38
PPE35 2169660 p.Asn318Ile missense_variant 0.5
PPE35 2170351 p.Thr88Pro missense_variant 0.33
PPE35 2170714 c.-102A>T upstream_gene_variant 0.4
Rv1979c 2222283 c.882C>A synonymous_variant 0.33
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289402 c.-161T>A upstream_gene_variant 0.4
pncA 2289947 c.-706T>A upstream_gene_variant 0.5
kasA 2518619 p.Ser169Ala missense_variant 0.5
kasA 2519029 c.915C>T synonymous_variant 0.22
eis 2715152 p.Met61Leu missense_variant 0.2
folC 2746179 p.Thr474Ala missense_variant 0.29
folC 2747179 c.420T>G synonymous_variant 0.33
pepQ 2859433 p.Tyr329Phe missense_variant 0.3
pepQ 2859834 c.585T>G synonymous_variant 0.25
pepQ 2860210 p.Asp70Ala missense_variant 0.22
pepQ 2860241 p.Tyr60Asp missense_variant 0.29
pepQ 2860308 c.111C>T synonymous_variant 0.17
ribD 2986695 c.-144A>T upstream_gene_variant 0.29
ribD 2987314 p.Leu159Arg missense_variant 0.22
Rv2752c 3065138 p.Ile352Phe missense_variant 0.22
ald 3087396 p.Thr193Ala missense_variant 0.17
ald 3087723 p.Pro302Ser missense_variant 0.15
fbiD 3339548 p.Leu144Arg missense_variant 0.2
fbiD 3339698 p.Asp194Ala missense_variant 0.22
Rv3083 3448448 c.-56A>T upstream_gene_variant 0.4
fprA 3473895 c.-112T>G upstream_gene_variant 0.2
fprA 3474610 p.Pro202Thr missense_variant 0.31
Rv3236c 3612299 p.Ile273Asn missense_variant 0.22
Rv3236c 3612974 p.Ile48Ser missense_variant 0.33
Rv3236c 3612993 p.Ser42Ala missense_variant 0.25
Rv3236c 3613135 c.-19G>C upstream_gene_variant 0.25
fbiB 3641256 c.-279A>G upstream_gene_variant 0.43
rpoA 3877829 p.Val227Phe missense_variant 0.25
rpoA 3878400 c.108T>C synonymous_variant 0.18
rpoA 3878490 c.18C>A synonymous_variant 0.67
clpC1 4039545 p.Asp387Ala missense_variant 0.2
panD 4044362 c.-81T>A upstream_gene_variant 0.4
embC 4239897 p.Val12Ala missense_variant 0.17
embC 4239911 p.Thr17Ser missense_variant 0.22
embC 4240107 p.Leu82* stop_gained 0.22
embC 4240982 p.Ser374Arg missense_variant 0.2
embC 4242147 p.Asn762Thr missense_variant 0.33
embC 4242186 p.Asp775Ala missense_variant 0.4
embC 4242386 p.Asn842His missense_variant 0.17
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243764 p.Lys178* stop_gained 0.22
embA 4244362 p.Asn377Thr missense_variant 0.22
embA 4245599 p.Lys789Asn missense_variant 0.29
embB 4246534 p.Arg7Ser missense_variant 0.29
embB 4246709 p.Ser66Arg missense_variant 0.33
embB 4247028 p.Leu172Gln missense_variant 0.2
embB 4248309 p.Phe599Cys missense_variant 0.33
embB 4249145 p.Thr878Pro missense_variant 0.29
ethR 4328164 p.Ile206Val missense_variant 0.13
whiB6 4338373 p.Lys50Met missense_variant 0.33
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338676 c.-155T>G upstream_gene_variant 0.5
gid 4408473 c.-271C>A upstream_gene_variant 1.0
Rv3083 3448497 c.-6_*1408del transcript_ablation 1.0