TB-Profiler result

Run: ERR4816100
Summary

Run ID: ERR4816100

Sample name:

Date: 01-04-2023 14:14:31

Number of reads: 2349731

Percentage reads mapped: 75.28

Strain: lineage4.1.3;lineage4.1.2.1;lineage1.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 0.66
lineage1 Indo-Oceanic EAI RD239 0.35
lineage4.1 Euro-American T;X;H None 0.6
lineage1.1 Indo-Oceanic EAI3;EAI4;EAI5;EAI6 RD239 0.36
lineage4.1.3 Euro-American T;X;H None 0.49
lineage1.1.2 Indo-Oceanic EAI3;EAI5 RD239 0.4
lineage4.1.2.1 Euro-American (Haarlem) T1;H1 RD182 0.08
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 0.34
gyrB 6124 c.885C>T synonymous_variant 0.35
gyrA 6670 c.-632G>C upstream_gene_variant 0.13
gyrA 6676 c.-626T>G upstream_gene_variant 0.13
gyrA 6730 c.-572A>G upstream_gene_variant 0.13
gyrA 6760 c.-542G>C upstream_gene_variant 0.14
gyrA 6764 c.-538C>T upstream_gene_variant 0.13
gyrA 6772 c.-530C>G upstream_gene_variant 0.14
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7394 c.93T>C synonymous_variant 0.13
gyrA 7442 c.141G>C synonymous_variant 0.14
gyrA 7457 c.156T>C synonymous_variant 0.16
gyrA 7480 p.Phe60Tyr missense_variant 0.14
gyrA 7484 c.183T>C synonymous_variant 0.14
gyrA 7490 c.189C>G synonymous_variant 0.13
gyrA 7496 c.195C>G synonymous_variant 0.16
gyrA 7499 c.198G>C synonymous_variant 0.17
gyrA 7523 c.222C>G synonymous_variant 0.16
gyrA 7526 c.225G>C synonymous_variant 0.17
gyrA 7532 c.231T>G synonymous_variant 0.18
gyrA 7559 c.258G>A synonymous_variant 0.15
gyrA 7571 c.270G>C synonymous_variant 0.22
gyrA 7574 c.273G>C synonymous_variant 0.16
gyrA 7585 p.Ser95Thr missense_variant 0.99
gyrA 8435 c.1134C>G synonymous_variant 0.35
gyrA 8452 p.Ala384Val missense_variant 0.32
gyrA 8897 c.1596T>C synonymous_variant 0.16
gyrA 8915 c.1614A>G synonymous_variant 0.15
gyrA 8924 c.1623C>T synonymous_variant 0.14
gyrA 9122 c.1821C>A synonymous_variant 0.12
gyrA 9143 c.1842T>C synonymous_variant 0.59
gyrA 9182 c.1881T>C synonymous_variant 0.14
gyrA 9191 c.1890G>C synonymous_variant 0.14
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491173 c.391C>A synonymous_variant 0.13
fgd1 491742 c.960T>C synonymous_variant 0.33
mshA 575376 p.Ser10Leu missense_variant 0.32
ccsA 620688 c.798G>C synonymous_variant 0.15
rpoB 760112 c.306T>C synonymous_variant 0.14
rpoB 760115 c.309C>T synonymous_variant 0.13
rpoB 760118 c.312T>G synonymous_variant 0.16
rpoB 760121 c.315T>C synonymous_variant 0.16
rpoB 760130 p.Asp108Glu missense_variant 0.19
rpoB 760184 c.378A>G synonymous_variant 0.16
rpoB 760196 c.390C>G synonymous_variant 0.21
rpoB 760223 c.417T>C synonymous_variant 0.18
rpoB 760235 c.429T>C synonymous_variant 0.14
rpoB 760283 c.477G>C synonymous_variant 0.16
rpoB 760484 c.678A>G synonymous_variant 0.14
rpoB 760522 p.Ser239Asn missense_variant 0.14
rpoB 760634 c.828T>C synonymous_variant 0.14
rpoB 760661 c.855A>C synonymous_variant 0.14
rpoB 760674 c.868T>C synonymous_variant 0.13
rpoB 760679 c.873A>G synonymous_variant 0.14
rpoB 760683 c.877T>C synonymous_variant 0.14
rpoB 760887 p.Thr361Ala missense_variant 0.13
rpoB 760910 c.1104C>T synonymous_variant 0.15
rpoB 760928 c.1122G>C synonymous_variant 0.13
rpoB 760946 c.1140A>G synonymous_variant 0.16
rpoB 761021 c.1215G>C synonymous_variant 0.16
rpoB 761027 c.1221A>G synonymous_variant 0.16
rpoB 761036 c.1230G>C synonymous_variant 0.18
rpoB 761037 c.1231T>C synonymous_variant 0.19
rpoB 761057 c.1251G>C synonymous_variant 0.22
rpoB 761102 c.1296A>G synonymous_variant 0.29
rpoB 761129 c.1323G>C synonymous_variant 0.13
rpoB 761133 c.1327T>C synonymous_variant 0.16
rpoB 761195 c.1389G>C synonymous_variant 0.12
rpoB 761219 c.1413G>C synonymous_variant 0.17
rpoB 761249 c.1443A>G synonymous_variant 0.24
rpoB 761255 c.1449T>G synonymous_variant 0.23
rpoB 761261 c.1455G>T synonymous_variant 0.18
rpoB 761306 c.1500C>G synonymous_variant 0.16
rpoB 761312 c.1506G>C synonymous_variant 0.19
rpoB 761327 c.1521A>G synonymous_variant 0.27
rpoB 761330 c.1524G>C synonymous_variant 0.16
rpoB 761354 c.1548C>T synonymous_variant 0.17
rpoB 761360 c.1554T>C synonymous_variant 0.22
rpoB 761362 p.Ser519Thr missense_variant 0.23
rpoB 761373 p.Val523His missense_variant 0.19
rpoB 761537 c.1731C>G synonymous_variant 0.21
rpoB 761570 c.1764T>C synonymous_variant 0.21
rpoB 761573 c.1767C>G synonymous_variant 0.22
rpoB 761579 c.1773G>C synonymous_variant 0.2
rpoB 761612 c.1806G>T synonymous_variant 0.16
rpoB 761615 c.1809A>C synonymous_variant 0.25
rpoB 761636 c.1830G>T synonymous_variant 0.21
rpoB 761645 c.1839C>G synonymous_variant 0.19
rpoB 761648 c.1842T>C synonymous_variant 0.19
rpoB 762008 c.2202C>T synonymous_variant 0.16
rpoB 762233 c.2427G>C synonymous_variant 0.19
rpoC 762920 c.-450C>T upstream_gene_variant 0.15
rpoC 762923 c.-447C>G upstream_gene_variant 0.15
rpoC 762959 c.-411G>C upstream_gene_variant 0.15
rpoC 762962 c.-408C>T upstream_gene_variant 0.15
rpoC 762989 c.-381G>A upstream_gene_variant 0.14
rpoC 762995 c.-375G>T upstream_gene_variant 0.2
rpoC 763031 c.-339T>C upstream_gene_variant 0.43
rpoC 763040 c.-330C>G upstream_gene_variant 0.25
rpoC 763070 c.-300T>C upstream_gene_variant 0.24
rpoC 763085 c.-285C>G upstream_gene_variant 0.15
rpoC 763088 c.-282C>G upstream_gene_variant 0.15
rpoC 763094 c.-276G>C upstream_gene_variant 0.17
rpoC 763115 c.-255T>C upstream_gene_variant 0.26
rpoC 763127 c.-243G>C upstream_gene_variant 0.14
rpoC 763136 c.-234C>T upstream_gene_variant 0.2
rpoC 763142 c.-228C>G upstream_gene_variant 0.15
rpoC 763157 c.-213G>T upstream_gene_variant 0.14
rpoC 763166 c.-204A>G upstream_gene_variant 0.14
rpoC 763402 c.33C>G synonymous_variant 0.18
rpoC 763411 c.42T>G synonymous_variant 0.18
rpoC 763414 c.45T>C synonymous_variant 0.18
rpoC 763441 c.72C>T synonymous_variant 0.19
rpoC 763444 c.75T>C synonymous_variant 0.19
rpoC 763456 c.87A>G synonymous_variant 0.2
rpoC 763546 c.177A>G synonymous_variant 0.17
rpoC 763660 c.291T>G synonymous_variant 0.18
rpoC 763675 c.306C>G synonymous_variant 0.17
rpoC 763702 c.333C>G synonymous_variant 0.14
rpoC 763717 c.348T>C synonymous_variant 0.21
rpoC 763723 c.354G>C synonymous_variant 0.18
rpoC 763732 c.363C>G synonymous_variant 0.19
rpoC 763741 c.372C>T synonymous_variant 0.17
rpoC 763765 c.396T>C synonymous_variant 0.15
rpoC 763884 p.Ala172Val missense_variant 0.52
rpoC 763886 c.517C>A synonymous_variant 0.55
rpoC 764257 c.888G>C synonymous_variant 0.2
rpoC 764266 c.897T>C synonymous_variant 0.16
rpoC 764269 c.900G>C synonymous_variant 0.17
rpoC 764278 c.909A>G synonymous_variant 0.15
rpoC 764365 c.996C>T synonymous_variant 0.15
rpoC 764380 c.1011G>C synonymous_variant 0.14
rpoC 764405 c.1036A>C synonymous_variant 0.21
rpoC 764428 c.1059G>C synonymous_variant 0.18
rpoC 764431 c.1062G>C synonymous_variant 0.18
rpoC 764434 c.1065A>G synonymous_variant 0.18
rpoC 764458 c.1089G>C synonymous_variant 0.2
rpoC 764461 c.1092A>G synonymous_variant 0.19
rpoC 764497 c.1128A>G synonymous_variant 0.24
rpoC 764506 c.1137C>T synonymous_variant 0.24
rpoC 764527 c.1158C>T synonymous_variant 0.22
rpoC 764530 c.1161C>T synonymous_variant 0.17
rpoC 764536 c.1167G>T synonymous_variant 0.16
rpoC 764539 c.1170C>G synonymous_variant 0.23
rpoC 764548 c.1179G>A synonymous_variant 0.17
rpoC 764554 c.1185C>T synonymous_variant 0.24
rpoC 764566 c.1197C>G synonymous_variant 0.28
rpoC 764575 c.1206T>G synonymous_variant 0.27
rpoC 764578 c.1209C>G synonymous_variant 0.2
rpoC 764593 c.1224C>T synonymous_variant 0.22
rpoC 764602 c.1233C>T synonymous_variant 0.13
rpoC 764611 c.1242G>T synonymous_variant 0.23
rpoC 764626 c.1257C>T synonymous_variant 0.24
rpoC 764632 c.1263T>C synonymous_variant 0.22
rpoC 764635 c.1266C>T synonymous_variant 0.18
rpoC 764650 c.1281G>T synonymous_variant 0.24
rpoC 764752 c.1383G>C synonymous_variant 0.26
rpoC 764764 c.1395T>C synonymous_variant 0.3
rpoC 764809 c.1440C>T synonymous_variant 0.14
rpoC 764815 c.1446A>G synonymous_variant 0.25
rpoC 764827 c.1458G>C synonymous_variant 0.17
rpoC 764858 c.1489T>C synonymous_variant 0.21
rpoC 764875 c.1506C>A synonymous_variant 0.13
rpoC 764888 c.1519T>C synonymous_variant 0.15
rpoC 764911 c.1542A>G synonymous_variant 0.14
rpoC 764932 c.1563C>A synonymous_variant 0.17
rpoC 764948 c.1579T>C synonymous_variant 0.17
rpoC 764968 c.1599T>C synonymous_variant 0.17
rpoC 765019 c.1650A>G synonymous_variant 0.15
rpoC 765150 p.Gly594Glu missense_variant 0.61
rpoC 765171 p.Pro601Leu missense_variant 0.31
rpoC 765352 c.1983G>C synonymous_variant 0.16
rpoC 765421 c.2052C>G synonymous_variant 0.2
rpoC 765529 c.2160C>T synonymous_variant 0.15
rpoC 765541 c.2172C>G synonymous_variant 0.14
rpoC 765553 c.2184C>T synonymous_variant 0.14
rpoC 765556 c.2187G>C synonymous_variant 0.15
rpoC 765559 c.2190G>C synonymous_variant 0.15
rpoC 765580 c.2211G>C synonymous_variant 0.13
rpoC 765700 c.2331T>C synonymous_variant 0.18
rpoC 765937 c.2568T>C synonymous_variant 0.14
rpoC 766384 c.3015A>G synonymous_variant 0.15
rpoC 766390 c.3021C>T synonymous_variant 0.13
rpoC 766607 p.Ile1080Leu missense_variant 0.14
rpoC 766630 c.3261G>C synonymous_variant 0.15
rpoC 767098 c.3729T>C synonymous_variant 0.17
rpoC 767119 c.3750A>G synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.62
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781421 c.-139C>A upstream_gene_variant 0.55
rpsL 781832 c.273T>C synonymous_variant 0.16
rpsL 781868 c.309T>C synonymous_variant 0.18
rpsL 781871 c.312G>C synonymous_variant 0.18
rpsL 781892 c.333A>G synonymous_variant 0.18
rpsL 781898 c.339A>T synonymous_variant 0.18
rpsL 781916 c.357T>C synonymous_variant 0.17
fbiC 1303818 c.888C>G synonymous_variant 0.21
fbiC 1303836 c.906G>C synonymous_variant 0.22
fbiC 1303845 c.915C>G synonymous_variant 0.22
fbiC 1303846 p.Phe306Val missense_variant 0.22
fbiC 1303854 c.924T>C synonymous_variant 0.22
fbiC 1303860 c.930A>C synonymous_variant 0.22
fbiC 1303884 c.954T>G synonymous_variant 0.17
fbiC 1304610 c.1680C>T synonymous_variant 0.54
fbiC 1304856 c.1926C>G synonymous_variant 0.18
fbiC 1304869 c.1939C>T synonymous_variant 0.12
fbiC 1304928 c.1998T>C synonymous_variant 0.12
fbiC 1304958 c.2028T>G synonymous_variant 0.18
fbiC 1304983 c.2053C>T synonymous_variant 0.23
fbiC 1304994 c.2064A>G synonymous_variant 0.16
fbiC 1304995 p.Leu689Met missense_variant 0.16
fbiC 1305006 c.2076A>G synonymous_variant 0.15
embR 1417019 p.Cys110Tyr missense_variant 0.26
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 0.17
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.19
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.16
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.19
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.18
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.19
rrs 1472734 n.889C>T non_coding_transcript_exon_variant 0.17
rrs 1472741 n.896G>A non_coding_transcript_exon_variant 0.18
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.14
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.13
rrl 1473660 n.3G>A non_coding_transcript_exon_variant 0.19
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.18
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.18
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.13
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.14
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.21
rrl 1474181 n.524_525insT non_coding_transcript_exon_variant 0.19
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.18
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.19
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.22
rrl 1474282 n.625G>A non_coding_transcript_exon_variant 0.14
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.24
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.36
rrl 1474803 n.1146G>A non_coding_transcript_exon_variant 0.32
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.37
rrl 1475061 n.1406delA non_coding_transcript_exon_variant 0.17
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.21
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.33
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.39
rrl 1475120 n.1463G>T non_coding_transcript_exon_variant 0.47
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.35
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.12
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.14
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.16
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.16
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.23
rrl 1475406 n.1749T>G non_coding_transcript_exon_variant 0.14
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.15
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 0.19
rrl 1475443 n.1786G>A non_coding_transcript_exon_variant 0.17
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 0.18
rrl 1475475 n.1818C>T non_coding_transcript_exon_variant 0.22
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 0.19
rrl 1475480 n.1823A>T non_coding_transcript_exon_variant 0.19
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.17
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.33
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.21
rrl 1475531 n.1874C>T non_coding_transcript_exon_variant 0.14
rrl 1476295 n.2638C>T non_coding_transcript_exon_variant 0.16
rrl 1476297 n.2640C>T non_coding_transcript_exon_variant 0.16
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.16
rrl 1476311 n.2654G>A non_coding_transcript_exon_variant 0.17
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.32
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.28
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.27
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.19
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.21
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.14
inhA 1674589 p.Met130Leu missense_variant 0.13
inhA 1674660 c.459G>C synonymous_variant 0.15
inhA 1674703 c.502T>C synonymous_variant 0.15
inhA 1674708 c.507G>A synonymous_variant 0.16
inhA 1674718 c.517A>C synonymous_variant 0.17
rpsA 1833841 c.300C>G synonymous_variant 0.16
rpsA 1833847 c.306C>G synonymous_variant 0.18
rpsA 1833856 c.315A>G synonymous_variant 0.2
rpsA 1833874 c.333T>G synonymous_variant 0.13
rpsA 1833886 c.345C>G synonymous_variant 0.19
rpsA 1833928 c.387G>C synonymous_variant 0.24
rpsA 1833979 c.438T>C synonymous_variant 0.16
rpsA 1834000 c.459G>C synonymous_variant 0.19
rpsA 1834021 c.480C>T synonymous_variant 0.15
rpsA 1834030 c.489C>G synonymous_variant 0.19
rpsA 1834074 p.Lys178Arg missense_variant 0.13
rpsA 1834451 c.910T>C synonymous_variant 0.14
rpsA 1834489 c.948T>C synonymous_variant 0.13
rpsA 1834498 c.957C>T synonymous_variant 0.14
rpsA 1834528 c.987T>C synonymous_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.21
PPE35 2167926 p.Leu896Ser missense_variant 0.3
PPE35 2167983 p.Gly877Asp missense_variant 0.34
Rv1979c 2222308 p.Asp286Gly missense_variant 0.41
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518132 c.18C>T synonymous_variant 0.46
kasA 2518696 c.582C>G synonymous_variant 0.14
kasA 2518702 c.588C>T synonymous_variant 0.14
kasA 2518711 c.597A>G synonymous_variant 0.15
kasA 2518714 c.600A>C synonymous_variant 0.13
kasA 2518777 c.663C>T synonymous_variant 0.14
kasA 2518825 c.711T>C synonymous_variant 0.21
kasA 2519062 c.948T>G synonymous_variant 0.16
kasA 2519068 c.954C>T synonymous_variant 0.14
kasA 2519072 p.Ala320Thr missense_variant 0.15
kasA 2519107 c.993T>C synonymous_variant 0.17
kasA 2519108 p.Asp332Gln missense_variant 0.17
kasA 2519116 c.1002C>G synonymous_variant 0.17
kasA 2519122 c.1008G>C synonymous_variant 0.19
kasA 2519137 c.1023T>G synonymous_variant 0.19
ahpC 2726051 c.-142G>A upstream_gene_variant 0.29
Rv2752c 3064632 c.1560C>T synonymous_variant 0.47
Rv2752c 3066376 c.-185C>T upstream_gene_variant 0.14
thyX 3067316 c.630A>G synonymous_variant 0.14
thyX 3067391 c.555G>C synonymous_variant 0.13
thyX 3067394 c.552G>C synonymous_variant 0.12
thyX 3067439 c.507A>G synonymous_variant 0.19
thyX 3067445 c.501C>G synonymous_variant 0.2
thyX 3067457 c.489C>G synonymous_variant 0.25
thyX 3067465 p.Ile161Val missense_variant 0.25
thyX 3067475 c.471A>G synonymous_variant 0.25
thyX 3067490 c.456C>G synonymous_variant 0.25
thyX 3067493 c.453A>G synonymous_variant 0.28
thyX 3067515 p.Ser144Thr missense_variant 0.25
thyX 3067718 c.228C>G synonymous_variant 0.14
thyX 3067721 c.225T>C synonymous_variant 0.14
thyA 3074175 c.297A>G synonymous_variant 0.13
ald 3086788 c.-32T>C upstream_gene_variant 0.98
Rv3083 3448714 p.Asp71His missense_variant 0.47
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.98
fprA 3474597 c.591C>A synonymous_variant 0.37
fprA 3475159 p.Asn385Asp missense_variant 0.44
rpoA 3877743 c.765T>C synonymous_variant 0.15
rpoA 3877764 c.744C>G synonymous_variant 0.17
rpoA 3877770 c.738A>G synonymous_variant 0.18
rpoA 3877776 c.732T>C synonymous_variant 0.18
rpoA 3877782 c.726T>C synonymous_variant 0.2
rpoA 3877785 c.723C>A synonymous_variant 0.14
rpoA 3877818 c.690A>G synonymous_variant 0.2
rpoA 3878193 c.315T>C synonymous_variant 0.15
rpoA 3878217 c.291A>G synonymous_variant 0.15
rpoA 3878271 c.237T>C synonymous_variant 0.13
rpoA 3878578 c.-71C>A upstream_gene_variant 0.5
clpC1 4038388 c.2317T>C synonymous_variant 0.13
clpC1 4038530 p.Glu725Asp missense_variant 0.15
clpC1 4038596 c.2109A>G synonymous_variant 0.2
clpC1 4038953 c.1752A>G synonymous_variant 0.15
clpC1 4038956 c.1749T>C synonymous_variant 0.16
clpC1 4038965 c.1740T>C synonymous_variant 0.16
clpC1 4038971 c.1734T>C synonymous_variant 0.14
clpC1 4038974 c.1731T>C synonymous_variant 0.14
clpC1 4038989 c.1716T>C synonymous_variant 0.16
clpC1 4039064 c.1641C>T synonymous_variant 0.15
clpC1 4039274 c.1431G>C synonymous_variant 0.14
clpC1 4039338 p.Thr456Gln missense_variant 0.15
clpC1 4039694 c.1011G>C synonymous_variant 0.17
clpC1 4039931 c.774T>C synonymous_variant 0.18
clpC1 4039934 c.771G>C synonymous_variant 0.14
clpC1 4039943 c.762G>C synonymous_variant 0.15
clpC1 4039946 c.759A>G synonymous_variant 0.16
clpC1 4039949 c.756G>C synonymous_variant 0.15
clpC1 4039952 c.753T>C synonymous_variant 0.22
clpC1 4039958 c.747G>C synonymous_variant 0.2
clpC1 4039964 c.741C>G synonymous_variant 0.18
clpC1 4039975 p.Asp244Asn missense_variant 0.14
clpC1 4039979 c.726C>G synonymous_variant 0.25
clpC1 4039982 c.723G>A synonymous_variant 0.16
clpC1 4039988 c.717C>G synonymous_variant 0.13
clpC1 4040000 c.705C>T synonymous_variant 0.15
clpC1 4040021 c.684A>C synonymous_variant 0.14
clpC1 4040033 c.672G>C synonymous_variant 0.16
clpC1 4040093 c.612C>G synonymous_variant 0.15
clpC1 4040105 c.600C>G synonymous_variant 0.15
clpC1 4040267 c.438A>G synonymous_variant 0.15
clpC1 4040291 c.414G>C synonymous_variant 0.13
clpC1 4040330 c.375C>G synonymous_variant 0.14
clpC1 4040517 p.Val63Ala missense_variant 0.27
embC 4240671 p.Thr270Ile missense_variant 0.44
embC 4241042 p.Asn394Asp missense_variant 0.39
embC 4241611 c.1749G>C synonymous_variant 0.18
embC 4241614 c.1752A>C synonymous_variant 0.15
embC 4241727 p.Phe622Tyr missense_variant 0.15
embC 4241741 p.Val627Leu missense_variant 0.14
embC 4241747 p.Val629Leu missense_variant 0.15
embC 4241750 p.Leu630Val missense_variant 0.14
embC 4241755 c.1893C>G synonymous_variant 0.14
embC 4241770 c.1908T>C synonymous_variant 0.14
embC 4241791 c.1929G>C synonymous_variant 0.13
embC 4241794 c.1932C>G synonymous_variant 0.13
embC 4241797 c.1935C>T synonymous_variant 0.12
embC 4241809 c.1947A>C synonymous_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.69
embA 4243848 p.Val206Met missense_variant 0.43
embA 4245137 c.1905T>C synonymous_variant 0.13
embA 4245149 c.1917C>G synonymous_variant 0.15
embA 4245182 c.1950T>C synonymous_variant 0.14
embA 4245969 p.Pro913Ser missense_variant 0.45
embB 4247356 c.843C>T synonymous_variant 0.53
embB 4247470 c.957T>C synonymous_variant 0.14
embB 4247491 c.978G>C synonymous_variant 0.14
embB 4247646 p.Glu378Ala missense_variant 0.38
embB 4247893 c.1380C>T synonymous_variant 0.16
embB 4247899 p.Met462Ile missense_variant 0.17
embB 4247905 c.1392G>C synonymous_variant 0.16
embB 4247940 p.Leu476Trp missense_variant 0.14
embB 4247945 c.1432T>C synonymous_variant 0.15
embB 4247951 p.Ser480Ala missense_variant 0.14
embB 4247956 c.1443G>C synonymous_variant 0.15
aftB 4268683 p.Gly52Ser missense_variant 0.53
ubiA 4269387 p.Glu149Asp missense_variant 0.4
aftB 4269606 c.-770T>C upstream_gene_variant 0.31
whiB6 4338441 p.Tyr27* stop_gained 0.37
whiB6 4338449 p.Ala25Pro missense_variant 0.39
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 0.24
gid 4407588 c.615A>G synonymous_variant 0.28
gid 4407873 c.330G>T synonymous_variant 0.26