TB-Profiler result

Run: SRR6785227
Summary

Run ID: SRR6785227

Sample name:

Date: 04-04-2023 15:38:33

Number of reads: 3529150

Percentage reads mapped: 83.75

Strain: lineage2.2.1

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 0.98
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.99
lineage2.2.1 East-Asian (Beijing) Beijing-RD181 RD105;RD207;RD181 0.98
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpsL 781687 p.Lys43Arg missense_variant 0.85 streptomycin
rrs 1472307 n.462C>T non_coding_transcript_exon_variant 0.25 streptomycin
embB 4247448 p.His312Arg missense_variant 0.15 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6238 c.999G>A synonymous_variant 0.13
gyrB 6242 p.Arg335Ser missense_variant 0.13
gyrB 6250 c.1011A>G synonymous_variant 0.14
gyrB 6256 c.1017G>A synonymous_variant 0.15
gyrB 6280 c.1041T>C synonymous_variant 0.15
gyrB 6286 c.1047T>C synonymous_variant 0.13
gyrB 6289 c.1050C>T synonymous_variant 0.12
gyrB 6292 c.1053G>C synonymous_variant 0.13
gyrA 6307 c.-995T>G upstream_gene_variant 0.15
gyrA 6649 c.-653T>C upstream_gene_variant 0.15
gyrA 6655 c.-647T>C upstream_gene_variant 0.15
gyrA 6670 c.-632G>C upstream_gene_variant 0.15
gyrA 6673 c.-629A>C upstream_gene_variant 0.15
gyrA 6676 c.-626T>G upstream_gene_variant 0.15
gyrA 6700 c.-602T>C upstream_gene_variant 0.18
gyrA 6703 c.-599G>C upstream_gene_variant 0.14
gyrA 6709 c.-593A>G upstream_gene_variant 0.14
gyrA 6712 c.-590G>C upstream_gene_variant 0.14
gyrA 6728 c.-574_-572delCTAinsTTG upstream_gene_variant 0.14
gyrA 6742 c.-560A>G upstream_gene_variant 0.15
gyrA 6745 c.-557T>G upstream_gene_variant 0.15
gyrA 6751 c.-551G>C upstream_gene_variant 0.14
gyrA 6811 c.-491C>T upstream_gene_variant 0.12
gyrA 7186 c.-116C>G upstream_gene_variant 0.13
gyrA 7216 c.-86G>C upstream_gene_variant 0.17
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491106 c.324T>C synonymous_variant 0.13
fgd1 491130 c.348C>G synonymous_variant 0.15
fgd1 491144 p.Ala121Asp missense_variant 0.15
fgd1 491151 c.369G>A synonymous_variant 0.15
fgd1 491173 c.391C>A synonymous_variant 0.13
fgd1 491181 c.399T>C synonymous_variant 0.13
fgd1 491191 p.Gly137Arg missense_variant 0.13
fgd1 491232 c.450T>C synonymous_variant 0.14
fgd1 491241 p.Asp153Glu missense_variant 0.15
fgd1 491244 c.462T>C synonymous_variant 0.14
fgd1 491259 c.477T>C synonymous_variant 0.16
fgd1 491742 c.960T>C synonymous_variant 0.97
mshA 575907 p.Ala187Val missense_variant 0.89
ccsA 620625 p.Ile245Met missense_variant 0.99
rpoB 760196 c.390C>G synonymous_variant 0.14
rpoB 760223 c.417T>C synonymous_variant 0.14
rpoB 760235 c.429T>C synonymous_variant 0.15
rpoB 760283 c.477G>C synonymous_variant 0.14
rpoB 760298 c.492G>C synonymous_variant 0.15
rpoB 760307 c.501T>C synonymous_variant 0.13
rpoB 760328 c.522G>C synonymous_variant 0.13
rpoB 760340 c.534G>T synonymous_variant 0.13
rpoB 760361 c.555T>C synonymous_variant 0.14
rpoB 760370 c.564C>G synonymous_variant 0.14
rpoB 760376 p.Asp190Glu missense_variant 0.14
rpoB 760381 p.Thr192Met missense_variant 0.13
rpoB 760406 c.600G>C synonymous_variant 0.14
rpoB 760412 c.606C>G synonymous_variant 0.12
rpoB 760481 c.675G>C synonymous_variant 0.12
rpoB 760611 c.805T>C synonymous_variant 0.15
rpoB 760634 c.828T>C synonymous_variant 0.13
rpoB 760646 c.840C>G synonymous_variant 0.16
rpoB 760655 c.849A>G synonymous_variant 0.15
rpoB 760661 c.855A>C synonymous_variant 0.14
rpoB 760670 c.864G>C synonymous_variant 0.15
rpoB 760674 c.868T>C synonymous_variant 0.14
rpoB 760679 c.873A>G synonymous_variant 0.14
rpoB 760683 c.877T>C synonymous_variant 0.15
rpoB 761102 c.1296A>G synonymous_variant 0.17
rpoB 761165 c.1359G>C synonymous_variant 0.14
rpoB 761207 c.1401C>T synonymous_variant 0.13
rpoB 761261 c.1455G>T synonymous_variant 0.13
rpoB 761306 c.1500C>G synonymous_variant 0.14
rpoB 762101 c.2295C>G synonymous_variant 0.14
rpoB 762114 p.Ile770Val missense_variant 0.15
rpoB 762131 c.2325C>G synonymous_variant 0.16
rpoB 762140 c.2334G>C synonymous_variant 0.14
rpoB 762143 c.2337T>C synonymous_variant 0.13
rpoB 762149 c.2343G>C synonymous_variant 0.15
rpoB 762167 c.2361T>C synonymous_variant 0.15
rpoB 762176 c.2370T>C synonymous_variant 0.16
rpoB 762185 c.2379G>C synonymous_variant 0.17
rpoB 762206 c.2400C>G synonymous_variant 0.17
rpoB 762233 c.2427G>C synonymous_variant 0.14
rpoB 762246 c.2440C>T synonymous_variant 0.14
rpoC 762419 c.-951C>G upstream_gene_variant 0.12
rpoC 762434 c.-936T>C upstream_gene_variant 0.15
rpoC 762449 c.-921C>A upstream_gene_variant 0.17
rpoC 762467 c.-903C>T upstream_gene_variant 0.18
rpoC 762488 c.-882G>C upstream_gene_variant 0.15
rpoB 762490 p.Val895Asp missense_variant 0.12
rpoC 762509 c.-861T>G upstream_gene_variant 0.13
rpoB 762510 p.Ala902Pro missense_variant 0.13
rpoC 762989 c.-381G>C upstream_gene_variant 0.16
rpoC 762995 c.-375G>T upstream_gene_variant 0.17
rpoC 763013 c.-357C>G upstream_gene_variant 0.17
rpoC 763028 c.-342T>C upstream_gene_variant 0.17
rpoC 763031 c.-339T>C upstream_gene_variant 0.99
rpoC 763034 c.-336C>G upstream_gene_variant 0.19
rpoC 763040 c.-330C>G upstream_gene_variant 0.22
rpoC 763070 c.-300T>C upstream_gene_variant 0.22
rpoC 763085 c.-285C>G upstream_gene_variant 0.2
rpoC 763115 c.-255T>C upstream_gene_variant 0.16
rpoC 763136 c.-234C>T upstream_gene_variant 0.14
rpoC 763158 c.-212C>T upstream_gene_variant 0.13
rpoC 763441 c.72C>T synonymous_variant 0.14
rpoC 763444 c.75T>C synonymous_variant 0.13
rpoC 763456 c.87A>G synonymous_variant 0.2
rpoC 763486 c.117T>G synonymous_variant 0.24
rpoC 763528 c.159G>A synonymous_variant 0.23
rpoC 763546 c.177A>G synonymous_variant 0.2
rpoC 763570 c.201G>C synonymous_variant 0.23
rpoC 763573 c.204G>C synonymous_variant 0.23
rpoC 763594 c.225C>T synonymous_variant 0.22
rpoC 763603 c.234C>T synonymous_variant 0.21
rpoC 763636 c.267T>C synonymous_variant 0.22
rpoC 763660 c.291T>G synonymous_variant 0.18
rpoC 763675 c.306C>G synonymous_variant 0.17
rpoC 763696 c.327T>C synonymous_variant 0.17
rpoC 763702 c.333C>G synonymous_variant 0.16
rpoC 763717 c.348T>C synonymous_variant 0.19
rpoC 763723 c.354G>C synonymous_variant 0.17
rpoC 763732 c.363C>G synonymous_variant 0.18
rpoC 763741 c.372C>T synonymous_variant 0.17
rpoC 763744 c.375G>C synonymous_variant 0.18
rpoC 763765 c.396T>C synonymous_variant 0.2
rpoC 763774 c.405G>C synonymous_variant 0.2
rpoC 763807 c.438T>C synonymous_variant 0.17
rpoC 763816 c.447C>G synonymous_variant 0.16
rpoC 763987 c.618C>T synonymous_variant 0.12
rpoC 764026 p.Leu219Phe missense_variant 0.13
rpoC 764098 c.729A>G synonymous_variant 0.14
rpoC 764101 c.732C>G synonymous_variant 0.13
rpoC 764102 p.Val245Ile missense_variant 0.13
rpoC 764112 p.Tyr248Phe missense_variant 0.13
rpoC 764140 c.771C>T synonymous_variant 0.18
rpoC 764188 c.819A>G synonymous_variant 0.17
rpoC 764195 p.Ser276Ile missense_variant 0.13
rpoC 764203 c.834G>C synonymous_variant 0.13
rpoC 764206 c.837T>C synonymous_variant 0.13
rpoC 764215 c.846A>G synonymous_variant 0.16
rpoC 764236 c.867G>A synonymous_variant 0.19
rpoC 764248 c.879C>G synonymous_variant 0.14
rpoC 764405 c.1036A>C synonymous_variant 0.13
rpoC 764489 c.1120C>T synonymous_variant 0.13
rpoC 764575 c.1206T>G synonymous_variant 0.13
rpoC 765383 p.Met672Leu missense_variant 0.15
rpoC 765404 p.Leu679Val missense_variant 0.17
rpoC 765409 c.2040T>C synonymous_variant 0.19
rpoC 765421 c.2052C>G synonymous_variant 0.21
rpoC 765478 c.2109T>C synonymous_variant 0.17
rpoC 765499 c.2130C>G synonymous_variant 0.17
rpoC 765529 c.2160C>T synonymous_variant 0.15
rpoC 765580 c.2211G>C synonymous_variant 0.13
rpoC 765613 p.His748Gln missense_variant 0.18
rpoC 765625 c.2256C>G synonymous_variant 0.16
rpoC 765631 p.Asp754Glu missense_variant 0.14
rpoC 765700 c.2331T>C synonymous_variant 0.17
rpoC 765734 c.2365T>C synonymous_variant 0.17
rpoC 765739 c.2370G>T synonymous_variant 0.15
rpoC 766645 p.Glu1092Asp missense_variant 0.9
rpoC 766765 c.3396A>C synonymous_variant 0.15
rpoC 766774 c.3405T>C synonymous_variant 0.16
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.99
mmpL5 776182 p.Asp767Asn missense_variant 1.0
mmpS5 779615 c.-710C>G upstream_gene_variant 0.96
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781703 c.144G>T synonymous_variant 0.12
rpsL 781728 c.169T>C synonymous_variant 0.14
rpsL 781736 c.177T>C synonymous_variant 0.13
rpsL 781742 c.183C>T synonymous_variant 0.13
rpsL 781748 c.189C>G synonymous_variant 0.13
rpsL 781754 c.195G>C synonymous_variant 0.16
rpsL 781760 c.201T>C synonymous_variant 0.15
rpsL 781772 c.213C>A synonymous_variant 0.15
rpsL 781808 c.249C>T synonymous_variant 0.14
rpsL 781811 c.252C>T synonymous_variant 0.15
rpsL 781832 c.273T>C synonymous_variant 0.15
rpsL 781838 c.279G>C synonymous_variant 0.16
rpsL 781841 c.282C>G synonymous_variant 0.15
rpsL 781865 c.306G>C synonymous_variant 0.14
rpsL 781868 c.309T>C synonymous_variant 0.14
rpsL 781871 c.312G>C synonymous_variant 0.14
rpsL 781877 c.318T>C synonymous_variant 0.14
rpsL 781892 c.333A>G synonymous_variant 0.15
rpsL 781898 c.339A>T synonymous_variant 0.14
rpsL 781929 p.Gly124Ser missense_variant 0.14
rplC 800693 c.-116A>G upstream_gene_variant 0.13
rplC 800703 c.-106T>C upstream_gene_variant 0.14
rplC 800715 c.-94A>C upstream_gene_variant 0.15
rplC 800720 c.-89T>C upstream_gene_variant 0.15
rplC 800723 c.-86C>G upstream_gene_variant 0.16
rplC 800747 c.-62C>G upstream_gene_variant 0.15
rplC 800771 c.-38C>T upstream_gene_variant 0.17
rplC 800794 c.-15A>G upstream_gene_variant 0.15
rplC 800796 c.-13A>G upstream_gene_variant 0.14
rplC 800798 c.-10_-9delGG upstream_gene_variant 0.14
rplC 800814 c.6A>G synonymous_variant 0.13
rplC 800817 c.9A>T synonymous_variant 0.13
fbiC 1304832 c.1902C>T synonymous_variant 0.14
fbiC 1304856 c.1926C>G synonymous_variant 0.14
fbiC 1304869 c.1939C>T synonymous_variant 0.14
fbiC 1304875 p.Ile649Val missense_variant 0.15
fbiC 1304883 p.Glu651Asp missense_variant 0.15
fbiC 1304891 p.Ile654Thr missense_variant 0.15
fbiC 1304893 p.Gly655Ser missense_variant 0.15
fbiC 1304907 c.1977C>G synonymous_variant 0.17
fbiC 1304910 c.1980G>C synonymous_variant 0.19
fbiC 1304916 c.1986T>C synonymous_variant 0.2
fbiC 1304928 c.1998T>C synonymous_variant 0.18
fbiC 1304937 c.2007G>C synonymous_variant 0.18
fbiC 1304958 c.2028T>G synonymous_variant 0.19
fbiC 1304983 c.2053C>T synonymous_variant 0.17
fbiC 1304994 c.2064A>G synonymous_variant 0.16
fbiC 1304995 p.Leu689Met missense_variant 0.16
Rv1258c 1406760 c.580_581insC frameshift_variant 1.0
atpE 1460852 c.-193C>G upstream_gene_variant 0.13
atpE 1460855 c.-190T>C upstream_gene_variant 0.13
atpE 1460882 c.-163T>C upstream_gene_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472300 n.455C>T non_coding_transcript_exon_variant 0.27
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.21
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.2
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.21
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.22
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.17
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.19
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.28
rrl 1473756 n.99G>A non_coding_transcript_exon_variant 0.23
rrl 1473758 n.101G>T non_coding_transcript_exon_variant 0.23
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.26
rrl 1473877 n.220G>A non_coding_transcript_exon_variant 0.45
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.42
rrl 1473899 n.242A>C non_coding_transcript_exon_variant 0.4
rrl 1473943 n.286G>T non_coding_transcript_exon_variant 0.33
rrl 1473986 n.329T>C non_coding_transcript_exon_variant 0.32
rrl 1473987 n.330G>A non_coding_transcript_exon_variant 0.3
rrl 1473995 n.338G>T non_coding_transcript_exon_variant 0.29
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.24
rrl 1474009 n.352A>G non_coding_transcript_exon_variant 0.21
rrl 1474012 n.355C>T non_coding_transcript_exon_variant 0.27
rrl 1474093 n.436G>T non_coding_transcript_exon_variant 0.27
rrl 1474099 n.442G>A non_coding_transcript_exon_variant 0.27
rrl 1474103 n.446A>T non_coding_transcript_exon_variant 0.24
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.3
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.36
rrl 1474181 n.524C>T non_coding_transcript_exon_variant 0.35
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.31
rrl 1474291 n.635_649delTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.17
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.16
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.16
rrl 1474356 n.699T>C non_coding_transcript_exon_variant 0.17
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 0.18
rrl 1474376 n.719T>C non_coding_transcript_exon_variant 0.22
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.17
rrl 1474904 n.1247G>A non_coding_transcript_exon_variant 0.12
rrl 1474956 n.1299C>T non_coding_transcript_exon_variant 0.15
rrl 1474961 n.1304T>G non_coding_transcript_exon_variant 0.17
rrl 1474963 n.1306G>A non_coding_transcript_exon_variant 0.17
rrl 1474964 n.1307T>C non_coding_transcript_exon_variant 0.17
rrl 1474970 n.1313G>A non_coding_transcript_exon_variant 0.17
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.19
rrl 1475088 n.1431A>T non_coding_transcript_exon_variant 0.2
rrl 1475199 n.1542G>A non_coding_transcript_exon_variant 0.32
rrl 1475206 n.1549C>T non_coding_transcript_exon_variant 0.27
rrl 1475209 n.1552G>C non_coding_transcript_exon_variant 0.3
rrl 1475213 n.1556C>T non_coding_transcript_exon_variant 0.3
rrl 1475249 n.1592T>C non_coding_transcript_exon_variant 0.33
rrl 1475252 n.1595C>T non_coding_transcript_exon_variant 0.31
rrl 1475266 n.1609T>C non_coding_transcript_exon_variant 0.31
rrl 1475275 n.1618C>T non_coding_transcript_exon_variant 0.28
rrl 1475276 n.1619T>C non_coding_transcript_exon_variant 0.25
rrl 1475291 n.1634A>C non_coding_transcript_exon_variant 0.32
rrl 1475313 n.1656G>A non_coding_transcript_exon_variant 0.26
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 0.23
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 0.15
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 0.14
rrl 1475402 n.1745C>T non_coding_transcript_exon_variant 0.19
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 0.23
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 0.38
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 0.42
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 0.45
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.33
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.32
rrl 1475638 n.1981C>T non_coding_transcript_exon_variant 0.19
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.22
rrl 1475657 n.2000A>G non_coding_transcript_exon_variant 0.29
rrl 1475659 n.2002G>T non_coding_transcript_exon_variant 0.31
rrl 1475765 n.2111delG non_coding_transcript_exon_variant 0.41
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.46
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.19
rrl 1476086 n.2429G>A non_coding_transcript_exon_variant 0.37
rrl 1476089 n.2432T>C non_coding_transcript_exon_variant 0.41
rrl 1476095 n.2438C>G non_coding_transcript_exon_variant 0.37
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.32
rrl 1476117 n.2460G>C non_coding_transcript_exon_variant 0.33
rrl 1476214 n.2557G>A non_coding_transcript_exon_variant 0.29
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.24
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.3
rrl 1476583 n.2926G>A non_coding_transcript_exon_variant 0.2
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.2
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.23
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 0.22
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.22
rrl 1476608 n.2951C>G non_coding_transcript_exon_variant 0.21
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.2
rrl 1476689 n.3032A>T non_coding_transcript_exon_variant 0.15
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 0.14
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 0.14
rrl 1476695 n.3038T>A non_coding_transcript_exon_variant 0.13
fabG1 1673380 c.-60C>G upstream_gene_variant 0.19
rpsA 1833721 c.180A>G synonymous_variant 0.14
rpsA 1833724 c.183C>G synonymous_variant 0.14
rpsA 1833727 c.186G>C synonymous_variant 0.14
rpsA 1833742 c.201A>G synonymous_variant 0.15
rpsA 1833745 c.204G>C synonymous_variant 0.15
rpsA 1833748 c.207C>G synonymous_variant 0.15
rpsA 1833787 c.246C>G synonymous_variant 0.14
rpsA 1833790 c.249T>C synonymous_variant 0.14
rpsA 1833802 c.261A>G synonymous_variant 0.15
rpsA 1833811 c.270G>T synonymous_variant 0.15
rpsA 1833838 c.297G>C synonymous_variant 0.14
rpsA 1833841 c.300C>G synonymous_variant 0.14
rpsA 1833847 c.306C>G synonymous_variant 0.15
rpsA 1833856 c.315A>G synonymous_variant 0.15
rpsA 1833940 c.399C>G synonymous_variant 0.13
rpsA 1834177 c.636A>C synonymous_variant 0.99
rpsA 1834489 c.948T>C synonymous_variant 0.13
rpsA 1834690 c.1149T>C synonymous_variant 0.17
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169221 c.1392T>C synonymous_variant 0.96
PPE35 2170048 p.Leu189Val missense_variant 0.18
PPE35 2170053 p.Thr187Ser missense_variant 0.18
PPE35 2170623 c.-11G>A upstream_gene_variant 0.98
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2714955 c.378C>T synonymous_variant 0.97
thyX 3067439 c.507A>G synonymous_variant 0.19
thyX 3067445 c.501C>G synonymous_variant 0.17
thyX 3067457 c.489C>G synonymous_variant 0.17
thyX 3067465 p.Ile161Val missense_variant 0.16
thyX 3067475 c.471A>G synonymous_variant 0.15
thyX 3067490 c.456C>G synonymous_variant 0.18
thyX 3067493 c.453A>G synonymous_variant 0.18
thyX 3067515 p.Ser144Thr missense_variant 0.17
thyX 3067530 p.Ala139Ser missense_variant 0.16
thyX 3067545 p.Glu134Ala missense_variant 0.17
thyX 3067549 p.Thr133Ala missense_variant 0.16
thyX 3067559 c.387C>G synonymous_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 0.97
rpoA 3877679 p.Ala277Ser missense_variant 0.13
rpoA 3877743 c.765T>C synonymous_variant 0.14
rpoA 3877764 c.744C>G synonymous_variant 0.14
rpoA 3877770 c.738A>G synonymous_variant 0.15
rpoA 3877776 c.732T>C synonymous_variant 0.13
rpoA 3877782 c.726T>C synonymous_variant 0.13
rpoA 3877791 c.717C>G synonymous_variant 0.13
rpoA 3877890 c.618C>T synonymous_variant 0.12
rpoA 3877896 c.612G>C synonymous_variant 0.13
rpoA 3877905 c.603A>G synonymous_variant 0.14
rpoA 3877909 p.Asn200Ser missense_variant 0.15
rpoA 3877920 c.588G>C synonymous_variant 0.15
rpoA 3877923 c.585C>T synonymous_variant 0.13
rpoA 3877926 c.582G>C synonymous_variant 0.14
rpoA 3877962 c.546G>T synonymous_variant 0.14
rpoA 3878217 c.291A>G synonymous_variant 0.13
rpoA 3878346 c.162T>C synonymous_variant 0.14
rpoA 3878376 c.132G>C synonymous_variant 0.14
rpoA 3878385 c.123C>G synonymous_variant 0.13
rpoA 3878388 c.120C>G synonymous_variant 0.13
rpoA 3878391 c.117T>C synonymous_variant 0.13
rpoA 3878415 c.93C>T synonymous_variant 0.16
rpoA 3878424 c.84G>C synonymous_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243460 c.228C>T synonymous_variant 1.0
embB 4246555 c.42G>C synonymous_variant 0.13
embB 4246556 p.Ala15Pro missense_variant 0.13
embB 4247434 c.921C>G synonymous_variant 0.14
embB 4247437 c.924A>G synonymous_variant 0.14
embB 4247440 c.927C>G synonymous_variant 0.14
embB 4247446 c.933C>T synonymous_variant 0.14
embB 4247464 c.951C>G synonymous_variant 0.18
embB 4247470 c.957T>C synonymous_variant 0.17
embB 4247491 c.978G>C synonymous_variant 0.16
embB 4247497 c.984T>C synonymous_variant 0.16
aftB 4267647 p.Asp397Gly missense_variant 0.98
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338711 c.-190C>A upstream_gene_variant 0.93
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407927 p.Glu92Asp missense_variant 0.99