TB-Profiler result

Run: ERR2228899
Summary

Run ID: ERR2228899

Sample name:

Date: 31-03-2023 16:25:17

Number of reads: 442692

Percentage reads mapped: 65.67

Strain: lineage4.8

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761196 p.Leu464Met missense_variant 0.15 rifampicin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.83 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.92 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6015 p.Asp259Gly missense_variant 0.12
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 8378 p.Asp359Glu missense_variant 0.14
gyrA 8492 c.1191G>A synonymous_variant 0.13
gyrA 9056 c.1755C>A synonymous_variant 0.14
fgd1 490759 c.-24A>G upstream_gene_variant 0.14
mshA 576635 c.1291delG frameshift_variant 0.13
rpoB 761147 c.1341C>T synonymous_variant 0.21
rpoB 761150 c.1344A>C synonymous_variant 0.23
rpoB 761159 c.1353G>C synonymous_variant 0.23
rpoB 761160 c.1354C>T synonymous_variant 0.23
rpoB 761165 c.1359G>C synonymous_variant 0.21
rpoB 761175 c.1369C>T synonymous_variant 0.17
rpoB 761180 c.1374A>T synonymous_variant 0.17
rpoB 761186 p.Glu460Asp missense_variant 0.17
rpoB 761195 c.1389G>C synonymous_variant 0.15
rpoB 761207 c.1401C>T synonymous_variant 0.12
rpoB 761213 c.1407G>T synonymous_variant 0.22
rpoB 761231 c.1425C>T synonymous_variant 0.17
rpoB 761234 c.1428G>T synonymous_variant 0.16
rpoB 761246 c.1440C>T synonymous_variant 0.14
rpoB 761249 c.1443A>G synonymous_variant 0.14
rpoB 761261 c.1455G>T synonymous_variant 0.19
rpoB 761264 c.1458C>G synonymous_variant 0.19
rpoB 761516 c.1710G>C synonymous_variant 0.22
rpoB 761592 c.1788delC frameshift_variant 0.2
rpoB 761711 c.1905C>A synonymous_variant 0.25
rpoB 762197 c.2391C>T synonymous_variant 0.17
rpoB 762198 p.Gly798Cys missense_variant 0.17
rpoB 762209 c.2403C>T synonymous_variant 0.17
rpoB 762218 c.2412T>C synonymous_variant 0.31
rpoB 762233 c.2427G>C synonymous_variant 0.44
rpoB 762236 c.2430G>T synonymous_variant 0.44
rpoB 762245 c.2439G>T synonymous_variant 0.45
rpoB 762254 c.2448T>C synonymous_variant 0.27
rpoB 762257 c.2451C>G synonymous_variant 0.27
rpoB 762296 c.2490G>C synonymous_variant 0.13
rpoB 762429 p.Asp875Ile missense_variant 0.2
rpoB 762878 p.Ile1024Met missense_variant 0.13
rpoB 762879 p.Met1025Leu missense_variant 0.13
rpoC 762899 c.-471G>T upstream_gene_variant 0.19
rpoC 762920 c.-450C>T upstream_gene_variant 0.21
rpoB 762930 p.Pro1042Thr missense_variant 0.17
rpoC 762971 c.-399G>C upstream_gene_variant 0.15
rpoB 763017 p.Gln1071Glu missense_variant 0.2
rpoC 763136 c.-234C>T upstream_gene_variant 0.17
rpoC 763528 c.159G>A synonymous_variant 0.17
rpoC 763534 c.165T>C synonymous_variant 0.16
rpoC 763537 c.168C>G synonymous_variant 0.15
rpoC 763546 c.177A>G synonymous_variant 0.15
rpoC 763570 c.201G>C synonymous_variant 0.13
rpoC 763573 c.204G>C synonymous_variant 0.13
rpoC 763594 c.225C>T synonymous_variant 0.12
rpoC 764896 c.1527C>T synonymous_variant 0.12
rpoC 765499 c.2130C>G synonymous_variant 0.2
rpoC 765973 c.2604C>G synonymous_variant 0.25
rpoC 765979 c.2610C>G synonymous_variant 0.25
rpoC 765982 c.2613C>T synonymous_variant 0.25
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776610 p.Met624Thr missense_variant 0.12
mmpL5 778963 c.-483G>T upstream_gene_variant 0.17
mmpR5 779109 p.Leu40Phe missense_variant 0.12
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rpsL 781817 c.258G>T synonymous_variant 0.12
rpsL 781829 c.270G>C synonymous_variant 0.21
rpsL 781832 c.273T>G synonymous_variant 0.23
rplC 800890 p.Val28Met missense_variant 0.2
fbiC 1303747 p.Thr273Ala missense_variant 1.0
fbiC 1304083 p.Gly385Cys missense_variant 0.4
embR 1417057 c.291G>A synonymous_variant 0.14
embR 1417138 c.210G>T synonymous_variant 0.14
embR 1417501 c.-154A>G upstream_gene_variant 0.13
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 0.43
rrs 1471929 n.84C>G non_coding_transcript_exon_variant 0.5
rrs 1471930 n.85G>T non_coding_transcript_exon_variant 0.5
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 0.5
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 0.5
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 0.5
rrs 1471967 n.122G>A non_coding_transcript_exon_variant 0.75
rrs 1471970 n.125G>A non_coding_transcript_exon_variant 0.67
rrs 1471972 n.127T>C non_coding_transcript_exon_variant 0.67
rrs 1471980 n.135G>T non_coding_transcript_exon_variant 0.67
rrs 1471981 n.136C>G non_coding_transcript_exon_variant 0.67
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 0.67
rrs 1471993 n.149_150delGC non_coding_transcript_exon_variant 0.67
rrs 1472009 n.164T>G non_coding_transcript_exon_variant 1.0
rrs 1472085 n.240C>T non_coding_transcript_exon_variant 0.75
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.86
rrs 1472107 n.262A>G non_coding_transcript_exon_variant 0.86
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.86
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.9
rrs 1472122 n.277G>T non_coding_transcript_exon_variant 1.0
rrs 1472123 n.278A>T non_coding_transcript_exon_variant 1.0
rrs 1472124 n.279C>T non_coding_transcript_exon_variant 1.0
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 1.0
rrs 1472160 n.315C>T non_coding_transcript_exon_variant 1.0
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.7
rrs 1472240 n.395G>A non_coding_transcript_exon_variant 0.62
rrs 1472251 n.406G>C non_coding_transcript_exon_variant 0.62
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.6
rrs 1472368 n.523A>G non_coding_transcript_exon_variant 0.43
rrs 1472396 n.551A>T non_coding_transcript_exon_variant 0.57
rrs 1472400 n.555C>T non_coding_transcript_exon_variant 0.4
rrs 1472507 n.662C>A non_coding_transcript_exon_variant 0.5
rrs 1472522 n.677T>G non_coding_transcript_exon_variant 0.73
rrs 1472557 n.712G>A non_coding_transcript_exon_variant 0.69
rrs 1472571 n.726G>T non_coding_transcript_exon_variant 0.73
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.69
rrs 1472582 n.737G>T non_coding_transcript_exon_variant 0.69
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.69
rrs 1472585 n.740A>C non_coding_transcript_exon_variant 0.69
rrs 1472623 n.778A>C non_coding_transcript_exon_variant 0.93
rrs 1472647 n.802C>T non_coding_transcript_exon_variant 0.96
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.95
rrs 1472675 n.830T>C non_coding_transcript_exon_variant 0.95
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.95
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.95
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.95
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.95
rrs 1472707 n.862A>T non_coding_transcript_exon_variant 0.96
rrs 1472767 n.922G>C non_coding_transcript_exon_variant 0.94
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.93
rrs 1472812 n.967A>T non_coding_transcript_exon_variant 0.9
rrs 1472837 n.992C>G non_coding_transcript_exon_variant 0.67
rrs 1472954 n.1110delC non_coding_transcript_exon_variant 1.0
rrs 1472958 n.1113_1114insC non_coding_transcript_exon_variant 0.92
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0
rrs 1472986 n.1141_1142insA non_coding_transcript_exon_variant 0.78
rrs 1472989 n.1145delA non_coding_transcript_exon_variant 0.78
rrs 1472996 n.1151T>C non_coding_transcript_exon_variant 0.79
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 1.0
rrs 1473081 n.1236C>T non_coding_transcript_exon_variant 0.94
rrs 1473088 n.1243A>G non_coding_transcript_exon_variant 0.89
rrs 1473091 n.1246G>A non_coding_transcript_exon_variant 0.86
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.86
rrs 1473094 n.1249T>G non_coding_transcript_exon_variant 0.86
rrs 1473099 n.1254T>G non_coding_transcript_exon_variant 0.86
rrs 1473100 n.1255G>C non_coding_transcript_exon_variant 0.86
rrs 1473102 n.1257C>T non_coding_transcript_exon_variant 0.86
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.86
rrs 1473109 n.1264T>G non_coding_transcript_exon_variant 0.86
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.86
rrs 1473120 n.1275C>T non_coding_transcript_exon_variant 0.6
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.6
rrs 1473122 n.1277T>G non_coding_transcript_exon_variant 0.6
rrs 1473123 n.1278A>G non_coding_transcript_exon_variant 0.6
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.81
rrs 1473164 n.1319C>T non_coding_transcript_exon_variant 0.93
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.93
rrs 1473226 n.1381C>G non_coding_transcript_exon_variant 0.8
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.81
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.79
rrs 1473288 n.1443C>G non_coding_transcript_exon_variant 0.82
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.82
rrs 1473292 n.1447G>T non_coding_transcript_exon_variant 0.82
rrs 1473294 n.1449A>G non_coding_transcript_exon_variant 0.82
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.82
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.92
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.92
rrs 1473319 n.1474C>T non_coding_transcript_exon_variant 0.92
rrs 1473324 n.1479G>A non_coding_transcript_exon_variant 0.92
rrs 1473347 n.1502C>A non_coding_transcript_exon_variant 0.17
rrl 1473445 n.-213G>T upstream_gene_variant 0.33
rrl 1473862 n.205C>T non_coding_transcript_exon_variant 0.5
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 0.5
rrl 1473887 n.230T>G non_coding_transcript_exon_variant 0.5
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.5
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.5
rrl 1473916 n.259C>A non_coding_transcript_exon_variant 1.0
rrl 1473922 n.265A>G non_coding_transcript_exon_variant 1.0
rrl 1473923 n.266C>G non_coding_transcript_exon_variant 1.0
rrl 1474166 n.509G>T non_coding_transcript_exon_variant 0.57
rrl 1474167 n.510T>C non_coding_transcript_exon_variant 0.57
rrl 1474184 n.527C>T non_coding_transcript_exon_variant 0.75
rrl 1474186 n.529A>G non_coding_transcript_exon_variant 0.75
rrl 1474197 n.540C>T non_coding_transcript_exon_variant 0.92
rrl 1474202 n.545T>G non_coding_transcript_exon_variant 0.91
rrl 1474218 n.561T>G non_coding_transcript_exon_variant 1.0
rrl 1474253 n.596A>T non_coding_transcript_exon_variant 0.88
rrl 1474264 n.607T>G non_coding_transcript_exon_variant 0.75
rrl 1474265 n.608G>T non_coding_transcript_exon_variant 0.75
rrl 1474266 n.609T>C non_coding_transcript_exon_variant 0.75
rrl 1474269 n.612C>A non_coding_transcript_exon_variant 0.75
rrl 1474271 n.614A>G non_coding_transcript_exon_variant 0.75
rrl 1474275 n.618T>G non_coding_transcript_exon_variant 0.75
rrl 1474287 n.631_649delCCTTTTCCTCTCCGGAGGA non_coding_transcript_exon_variant 0.75
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.67
rrl 1474348 n.691C>T non_coding_transcript_exon_variant 0.57
rrl 1474351 n.694G>T non_coding_transcript_exon_variant 0.5
rrl 1474454 n.797G>A non_coding_transcript_exon_variant 0.67
rrl 1474467 n.810A>T non_coding_transcript_exon_variant 0.71
rrl 1474476 n.819C>T non_coding_transcript_exon_variant 0.64
rrl 1474488 n.831G>A non_coding_transcript_exon_variant 0.72
rrl 1474496 n.839C>T non_coding_transcript_exon_variant 0.72
rrl 1474497 n.840G>C non_coding_transcript_exon_variant 0.72
rrl 1474506 n.849C>G non_coding_transcript_exon_variant 0.72
rrl 1474507 n.850G>T non_coding_transcript_exon_variant 0.72
rrl 1474516 n.859C>T non_coding_transcript_exon_variant 0.72
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 0.72
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 0.72
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.59
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.59
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.59
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 0.79
rrl 1474558 n.901G>A non_coding_transcript_exon_variant 0.79
rrl 1474582 n.925T>A non_coding_transcript_exon_variant 0.83
rrl 1474749 n.1092C>T non_coding_transcript_exon_variant 0.64
rrl 1474752 n.1096delA non_coding_transcript_exon_variant 0.64
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.73
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.71
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.71
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.71
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.71
rrl 1474798 n.1141C>T non_coding_transcript_exon_variant 0.71
rrl 1474799 n.1143delT non_coding_transcript_exon_variant 0.71
rrl 1474803 n.1146_1147insA non_coding_transcript_exon_variant 0.71
rrl 1474806 n.1149A>C non_coding_transcript_exon_variant 0.71
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.76
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.8
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.8
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.8
rrl 1474853 n.1196A>G non_coding_transcript_exon_variant 0.8
rrl 1474864 n.1207C>T non_coding_transcript_exon_variant 0.88
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.86
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.86
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 1.0
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 1.0
rrl 1475747 n.2090A>G non_coding_transcript_exon_variant 1.0
rrl 1475751 n.2094C>A non_coding_transcript_exon_variant 1.0
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0
rrl 1475767 n.2110G>T non_coding_transcript_exon_variant 1.0
rrl 1475777 n.2120A>T non_coding_transcript_exon_variant 1.0
rrl 1475781 n.2124T>C non_coding_transcript_exon_variant 0.85
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 0.94
rrl 1475877 n.2220C>T non_coding_transcript_exon_variant 0.94
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 0.94
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 0.94
rrl 1475892 n.2235A>C non_coding_transcript_exon_variant 0.94
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.94
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.94
rrl 1475906 n.2249C>T non_coding_transcript_exon_variant 0.94
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 0.93
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.93
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 1.0
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 1.0
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 1.0
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0
rrl 1475991 n.2334T>A non_coding_transcript_exon_variant 1.0
rrl 1475993 n.2336C>T non_coding_transcript_exon_variant 1.0
rrl 1475996 n.2339T>G non_coding_transcript_exon_variant 1.0
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 0.5
rrl 1476117 n.2460G>A non_coding_transcript_exon_variant 0.5
rrl 1476130 n.2473G>A non_coding_transcript_exon_variant 1.0
rrl 1476131 n.2474C>T non_coding_transcript_exon_variant 1.0
rrl 1476141 n.2484A>G non_coding_transcript_exon_variant 1.0
rrl 1476153 n.2496T>C non_coding_transcript_exon_variant 1.0
rrl 1476164 n.2507A>G non_coding_transcript_exon_variant 0.86
rrl 1476165 n.2508T>G non_coding_transcript_exon_variant 0.88
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 1.0
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 1.0
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 1.0
rrl 1476204 n.2547C>T non_coding_transcript_exon_variant 1.0
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.94
rrl 1476235 n.2578A>G non_coding_transcript_exon_variant 0.93
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.92
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.92
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.92
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.9
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 0.88
rrl 1476288 n.2635_2643delGCACCCCCG non_coding_transcript_exon_variant 0.67
rrl 1476299 n.2642C>T non_coding_transcript_exon_variant 0.5
rrl 1476301 n.2644_2645insCGGTGGCTT non_coding_transcript_exon_variant 0.5
rrl 1476307 n.2650A>T non_coding_transcript_exon_variant 0.5
rrl 1476309 n.2652G>C non_coding_transcript_exon_variant 0.5
rrl 1476311 n.2654G>C non_coding_transcript_exon_variant 0.5
rrl 1476312 n.2655T>C non_coding_transcript_exon_variant 0.5
rrl 1476316 n.2659G>A non_coding_transcript_exon_variant 0.67
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.8
rrl 1476363 n.2706A>G non_coding_transcript_exon_variant 0.78
rrl 1476366 n.2709A>C non_coding_transcript_exon_variant 0.78
rrl 1476368 n.2711T>C non_coding_transcript_exon_variant 0.78
rrl 1476369 n.2712C>T non_coding_transcript_exon_variant 0.88
rrl 1476374 n.2717T>G non_coding_transcript_exon_variant 0.89
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.89
rrl 1476385 n.2731delT non_coding_transcript_exon_variant 0.18
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 1.0
rrl 1476429 n.2772A>C non_coding_transcript_exon_variant 1.0
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 1.0
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 1.0
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 1.0
rrl 1476523 n.2866T>G non_coding_transcript_exon_variant 1.0
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 1.0
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 1.0
rrl 1476529 n.2872A>T non_coding_transcript_exon_variant 1.0
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 1.0
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 1.0
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 1.0
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 1.0
rrl 1476546 n.2889C>T non_coding_transcript_exon_variant 1.0
rrl 1476547 n.2890C>T non_coding_transcript_exon_variant 1.0
rrl 1476564 n.2907G>A non_coding_transcript_exon_variant 0.67
rrl 1476572 n.2915G>T non_coding_transcript_exon_variant 0.67
rrl 1476573 n.2916A>G non_coding_transcript_exon_variant 0.67
rpsA 1833976 c.435C>T synonymous_variant 0.18
rpsA 1833979 c.438T>C synonymous_variant 0.17
rpsA 1833985 c.444G>T synonymous_variant 0.17
rpsA 1833994 c.453G>C synonymous_variant 0.19
rpsA 1833997 c.456G>T synonymous_variant 0.19
rpsA 1834000 c.459G>T synonymous_variant 0.2
rpsA 1834012 c.471G>A synonymous_variant 0.12
rpsA 1834015 c.474G>C synonymous_variant 0.12
rpsA 1834018 c.477C>T synonymous_variant 0.12
rpsA 1834024 c.483G>C synonymous_variant 0.11
rpsA 1834034 p.Ile165Val missense_variant 0.11
rpsA 1834040 p.Lys167Gln missense_variant 0.11
rpsA 1834069 c.528G>C synonymous_variant 0.11
rpsA 1834090 c.549G>T synonymous_variant 0.14
rpsA 1834099 c.558C>G synonymous_variant 0.14
rpsA 1834105 c.564C>T synonymous_variant 0.14
rpsA 1834108 c.567C>G synonymous_variant 0.14
rpsA 1834114 c.573G>C synonymous_variant 0.12
tlyA 1917747 c.-193A>T upstream_gene_variant 0.29
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2101853 p.Leu397Arg missense_variant 0.22
katG 2154698 c.1414C>T synonymous_variant 0.15
katG 2156392 c.-281C>A upstream_gene_variant 0.22
PPE35 2167916 c.2696delT frameshift_variant 0.13
PPE35 2168728 p.Gly629Arg missense_variant 1.0
PPE35 2169278 c.1335T>C synonymous_variant 0.21
PPE35 2169281 c.1332T>G synonymous_variant 0.21
PPE35 2169287 c.1326T>C synonymous_variant 0.18
PPE35 2169293 c.1320T>C synonymous_variant 0.23
PPE35 2169308 c.1305C>T synonymous_variant 0.2
PPE35 2169322 c.1291T>C synonymous_variant 0.12
PPE35 2169323 c.1290C>G synonymous_variant 0.12
PPE35 2169326 c.1287C>T synonymous_variant 0.12
PPE35 2169596 p.Phe339Val missense_variant 0.12
PPE35 2169602 c.1011C>A synonymous_variant 0.12
PPE35 2169605 p.Asn336Thr missense_variant 0.12
PPE35 2169611 c.1002C>G synonymous_variant 0.11
PPE35 2169902 p.Leu237Phe missense_variant 0.17
PPE35 2169910 p.Asn235Tyr missense_variant 0.17
PPE35 2169990 p.Gly208Ala missense_variant 0.18
PPE35 2170147 p.Ser156Ala missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289426 c.-185G>T upstream_gene_variant 0.14
kasA 2518879 c.765A>G synonymous_variant 0.27
kasA 2518882 c.768C>A synonymous_variant 0.27
kasA 2519052 p.Thr313Met missense_variant 0.33
kasA 2519140 c.1026G>C synonymous_variant 0.29
kasA 2519143 c.1029G>C synonymous_variant 0.29
eis 2714504 p.His277Asn missense_variant 0.2
pepQ 2860203 p.Glu72Asp missense_variant 0.22
pepQ 2860594 c.-176C>A upstream_gene_variant 0.2
ribD 2986719 c.-120G>A upstream_gene_variant 0.33
Rv2752c 3064945 p.Pro416Gln missense_variant 0.12
Rv2752c 3065485 p.Ala236Val missense_variant 0.22
Rv2752c 3066074 p.Leu40Val missense_variant 0.12
Rv2752c 3066110 p.Gly28Ser missense_variant 0.12
Rv2752c 3066999 c.-808C>A upstream_gene_variant 0.15
thyX 3067401 p.Arg182Pro missense_variant 0.4
ald 3087301 p.Gly161Val missense_variant 0.14
ald 3087344 c.525C>A synonymous_variant 0.18
Rv3083 3448414 c.-90T>C upstream_gene_variant 0.14
fprA 3474987 c.981G>T synonymous_variant 0.25
whiB7 3568462 p.Gln73Arg missense_variant 0.15
alr 3840243 p.Ser393Asn missense_variant 0.18
alr 3840258 p.Tyr388Phe missense_variant 0.18
alr 3840769 p.Phe218Leu missense_variant 0.29
alr 3841546 c.-126C>A upstream_gene_variant 0.18
rpoA 3877971 p.Asp179Glu missense_variant 0.12
rpoA 3878034 c.474A>G synonymous_variant 0.13
rpoA 3878492 p.Arg6Cys missense_variant 0.15
clpC1 4039624 p.Gly361Cys missense_variant 0.13
clpC1 4039645 p.His354Asp missense_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243582 p.Ala117Val missense_variant 0.33
embA 4245010 p.Ala593Asp missense_variant 0.12
embA 4245269 p.Asn679Lys missense_variant 0.25
embA 4245488 c.2256G>T synonymous_variant 0.29
embB 4246154 c.-360G>A upstream_gene_variant 0.25
embB 4247907 p.Ile465Asn missense_variant 0.4
embB 4248154 c.1641G>C synonymous_variant 0.17
embB 4248507 p.Gly665Val missense_variant 0.12
ethA 4327467 p.Glu3Lys missense_variant 0.18
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407997 p.Gly69Val missense_variant 0.17
gid 4408313 c.-111A>G upstream_gene_variant 0.4
gid 4408375 c.-173G>A upstream_gene_variant 0.25
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0