TB-Profiler result

Run: SRR4033549
Summary

Run ID: SRR4033549

Sample name:

Date: 04-04-2023 06:10:06

Number of reads: 1341117

Percentage reads mapped: 81.76

Strain: lineage2.2.2

Drug-resistance: HR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage2 East-Asian Beijing RD105 1.0
lineage2.2 East-Asian (Beijing) Beijing-RD207 RD105;RD207 0.99
lineage2.2.2 East-Asian (Beijing) Beijing-RD105/RD207 RD105;RD207 0.96
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.33 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.26 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.13 kanamycin, capreomycin, aminoglycosides, amikacin
katG 2155388 c.723delC frameshift_variant 0.13 isoniazid
ethA 4326333 p.Ala381Pro missense_variant 1.0 ethionamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8896 p.Asp532Val missense_variant 0.12
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491027 p.Asn82Thr missense_variant 0.13
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 760206 p.Ile134Val missense_variant 0.11
rpoB 760235 c.429T>C synonymous_variant 0.12
rpoB 760244 c.438G>C synonymous_variant 0.1
rpoB 761234 c.1428G>C synonymous_variant 0.1
rpoB 761799 p.Arg665Trp missense_variant 0.13
rpoB 761961 p.Pro719Ser missense_variant 0.13
rpoB 762030 p.Thr742Ser missense_variant 0.13
rpoB 762053 c.2247T>C synonymous_variant 0.11
rpoB 762057 p.Ile751Val missense_variant 0.1
rpoB 762065 c.2259T>G synonymous_variant 0.11
rpoB 762098 c.2292C>G synonymous_variant 0.11
rpoB 762101 c.2295C>G synonymous_variant 0.12
rpoB 762114 p.Ile770Val missense_variant 0.13
rpoB 762308 c.2502G>A synonymous_variant 0.11
rpoB 762487 p.Pro894Leu missense_variant 0.12
rpoC 762551 c.-819C>A upstream_gene_variant 0.11
rpoB 762879 p.Met1025Leu missense_variant 0.14
rpoC 762887 c.-483G>C upstream_gene_variant 0.15
rpoC 762899 c.-471G>C upstream_gene_variant 0.18
rpoC 762917 c.-453C>G upstream_gene_variant 0.22
rpoC 762923 c.-447C>G upstream_gene_variant 0.2
rpoC 762929 c.-441G>C upstream_gene_variant 0.2
rpoC 762959 c.-411G>C upstream_gene_variant 0.13
rpoC 762962 c.-408C>T upstream_gene_variant 0.12
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoB 763044 p.Gln1080Lys missense_variant 0.11
rpoC 763094 c.-276G>C upstream_gene_variant 0.14
rpoC 763115 c.-255T>C upstream_gene_variant 0.14
rpoC 763127 c.-243G>C upstream_gene_variant 0.13
rpoB 763130 p.Glu1108Asp missense_variant 0.13
rpoB 763131 p.Pro1109Ser missense_variant 0.13
rpoC 763142 c.-228C>G upstream_gene_variant 0.12
rpoC 763148 c.-222G>C upstream_gene_variant 0.12
rpoC 763157 c.-213G>C upstream_gene_variant 0.1
rpoC 763618 c.249C>G synonymous_variant 0.18
rpoC 763622 p.Ala85Ser missense_variant 0.17
rpoC 763642 c.273G>C synonymous_variant 0.17
rpoC 763660 c.291T>C synonymous_variant 0.15
rpoC 763669 c.300C>G synonymous_variant 0.19
rpoC 763675 c.306C>G synonymous_variant 0.15
rpoC 764650 c.1281G>T synonymous_variant 0.14
rpoC 764662 c.1293G>C synonymous_variant 0.14
rpoC 764706 p.Leu446Gln missense_variant 0.16
rpoC 764716 c.1347G>C synonymous_variant 0.16
rpoC 764764 c.1395T>C synonymous_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
mmpL5 776182 p.Asp767Asn missense_variant 0.12
mmpS5 779615 c.-710C>G upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801137 p.Ser110Asn missense_variant 0.12
Rv1258c 1406722 p.Gly207Trp missense_variant 0.15
embR 1416485 p.Ala288Glu missense_variant 0.12
embR 1417294 c.54A>C synonymous_variant 0.11
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.34
rrs 1472148 n.303T>C non_coding_transcript_exon_variant 0.53
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.56
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.57
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.41
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.27
rrs 1472259 n.414C>A non_coding_transcript_exon_variant 0.26
rrs 1472494 n.649A>G non_coding_transcript_exon_variant 0.11
rrs 1472496 n.651T>G non_coding_transcript_exon_variant 0.1
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.53
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.6
rrs 1472581 n.736A>C non_coding_transcript_exon_variant 0.57
rrs 1472583 n.738T>C non_coding_transcript_exon_variant 0.56
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.56
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.34
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.37
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.21
rrs 1472674 n.829T>C non_coding_transcript_exon_variant 0.21
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.23
rrs 1472682 n.837T>A non_coding_transcript_exon_variant 0.22
rrs 1472683 n.838T>C non_coding_transcript_exon_variant 0.23
rrs 1472685 n.840G>A non_coding_transcript_exon_variant 0.21
rrs 1472687 n.842A>T non_coding_transcript_exon_variant 0.19
rrs 1472697 n.852T>C non_coding_transcript_exon_variant 0.19
rrs 1472701 n.856T>A non_coding_transcript_exon_variant 0.21
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.25
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.22
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.21
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.21
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 0.23
rrs 1472970 n.1125C>G non_coding_transcript_exon_variant 0.22
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 0.16
rrs 1472977 n.1132G>C non_coding_transcript_exon_variant 0.2
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 0.21
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.26
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.28
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.19
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.27
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.29
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.35
rrs 1473100 n.1255G>A non_coding_transcript_exon_variant 0.35
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 0.26
rrs 1473105 n.1260G>A non_coding_transcript_exon_variant 0.26
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.35
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.35
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.35
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.35
rrs 1473145 n.1300C>T non_coding_transcript_exon_variant 0.41
rrs 1473166 n.1321G>A non_coding_transcript_exon_variant 0.38
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.24
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.1
rrl 1474201 n.544T>C non_coding_transcript_exon_variant 0.25
rrl 1474202 n.545T>C non_coding_transcript_exon_variant 0.25
rrl 1474218 n.561T>A non_coding_transcript_exon_variant 0.32
rrl 1474249 n.592G>T non_coding_transcript_exon_variant 0.29
rrl 1474280 n.623C>T non_coding_transcript_exon_variant 0.12
rrl 1474281 n.624A>G non_coding_transcript_exon_variant 0.12
rrl 1474476 n.819C>G non_coding_transcript_exon_variant 0.13
rrl 1474483 n.826C>G non_coding_transcript_exon_variant 0.13
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 0.12
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 0.12
rrl 1474527 n.870T>C non_coding_transcript_exon_variant 0.12
rrl 1474528 n.871T>A non_coding_transcript_exon_variant 0.12
rrl 1474529 n.872A>G non_coding_transcript_exon_variant 0.12
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.14
rrl 1474540 n.883T>C non_coding_transcript_exon_variant 0.14
rrl 1474541 n.884G>T non_coding_transcript_exon_variant 0.14
rrl 1474542 n.885A>G non_coding_transcript_exon_variant 0.15
rrl 1474551 n.894G>C non_coding_transcript_exon_variant 0.16
rrl 1474558 n.901G>T non_coding_transcript_exon_variant 0.25
rrl 1474583 n.926C>T non_coding_transcript_exon_variant 0.41
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 0.64
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 0.67
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 0.64
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 0.64
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 0.64
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 0.64
rrl 1474639 n.982G>C non_coding_transcript_exon_variant 0.64
rrl 1474676 n.1019T>A non_coding_transcript_exon_variant 0.5
rrl 1474709 n.1053delT non_coding_transcript_exon_variant 0.35
rrl 1474714 n.1058delT non_coding_transcript_exon_variant 0.33
rrl 1474734 n.1077G>T non_coding_transcript_exon_variant 0.39
rrl 1474753 n.1097delC non_coding_transcript_exon_variant 0.43
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 0.39
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.43
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.35
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.43
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.5
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.47
rrl 1474831 n.1174A>C non_coding_transcript_exon_variant 0.5
rrl 1474904 n.1247G>C non_coding_transcript_exon_variant 0.26
rrl 1474905 n.1248T>C non_coding_transcript_exon_variant 0.26
rrl 1474913 n.1256T>C non_coding_transcript_exon_variant 0.22
rrl 1474932 n.1275C>T non_coding_transcript_exon_variant 0.19
rrl 1475060 n.1404delC non_coding_transcript_exon_variant 0.16
rrl 1475065 n.1408G>A non_coding_transcript_exon_variant 0.16
rrl 1475067 n.1410A>G non_coding_transcript_exon_variant 0.16
rrl 1475068 n.1411A>G non_coding_transcript_exon_variant 0.15
rrl 1475076 n.1419C>A non_coding_transcript_exon_variant 0.15
rrl 1475078 n.1421T>C non_coding_transcript_exon_variant 0.18
rrl 1475079 n.1422T>C non_coding_transcript_exon_variant 0.18
rrl 1475081 n.1424C>T non_coding_transcript_exon_variant 0.14
rrl 1475090 n.1433A>T non_coding_transcript_exon_variant 0.22
rrl 1475104 n.1447T>A non_coding_transcript_exon_variant 0.23
rrl 1475113 n.1456C>T non_coding_transcript_exon_variant 0.21
rrl 1475114 n.1457C>T non_coding_transcript_exon_variant 0.21
rrl 1475116 n.1459G>A non_coding_transcript_exon_variant 0.23
rrl 1475124 n.1467A>T non_coding_transcript_exon_variant 0.23
rrl 1475129 n.1472G>A non_coding_transcript_exon_variant 0.24
rrl 1475174 n.1517C>G non_coding_transcript_exon_variant 0.12
rrl 1475176 n.1519G>A non_coding_transcript_exon_variant 0.12
rrl 1475599 n.1942A>G non_coding_transcript_exon_variant 0.27
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.26
rrl 1475604 n.1950_1951delAT non_coding_transcript_exon_variant 0.27
rrl 1475608 n.1951T>G non_coding_transcript_exon_variant 0.28
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 0.24
rrl 1475642 n.1985T>C non_coding_transcript_exon_variant 0.21
rrl 1475649 n.1992A>G non_coding_transcript_exon_variant 0.23
rrl 1475655 n.1998T>G non_coding_transcript_exon_variant 0.31
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.33
rrl 1475752 n.2095C>G non_coding_transcript_exon_variant 0.4
rrl 1475753 n.2096C>G non_coding_transcript_exon_variant 0.41
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 0.38
rrl 1475762 n.2105G>T non_coding_transcript_exon_variant 0.38
rrl 1475763 n.2106C>T non_coding_transcript_exon_variant 0.38
rrl 1475764 n.2107A>C non_coding_transcript_exon_variant 0.38
rrl 1475765 n.2108A>G non_coding_transcript_exon_variant 0.38
rrl 1475775 n.2118G>T non_coding_transcript_exon_variant 0.43
rrl 1475776 n.2119G>C non_coding_transcript_exon_variant 0.43
rrl 1475883 n.2226A>C non_coding_transcript_exon_variant 0.37
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 0.37
rrl 1475896 n.2239A>G non_coding_transcript_exon_variant 0.33
rrl 1475897 n.2240T>C non_coding_transcript_exon_variant 0.33
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 0.32
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 0.33
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 0.41
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 0.35
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 0.24
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 0.21
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 0.22
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 0.24
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 0.22
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 0.21
rrl 1476179 n.2522C>T non_coding_transcript_exon_variant 0.45
rrl 1476194 n.2537A>G non_coding_transcript_exon_variant 0.4
rrl 1476200 n.2543A>T non_coding_transcript_exon_variant 0.42
rrl 1476201 n.2544C>T non_coding_transcript_exon_variant 0.42
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 0.35
rrl 1476221 n.2564T>C non_coding_transcript_exon_variant 0.41
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.42
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.29
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.31
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.27
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.24
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 0.3
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.29
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.3
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.35
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.4
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.36
rrl 1476523 n.2866T>C non_coding_transcript_exon_variant 0.34
rrl 1476524 n.2867C>A non_coding_transcript_exon_variant 0.34
rrl 1476525 n.2868A>G non_coding_transcript_exon_variant 0.33
rrl 1476536 n.2879G>A non_coding_transcript_exon_variant 0.33
rrl 1476538 n.2881A>G non_coding_transcript_exon_variant 0.33
rrl 1476539 n.2882A>G non_coding_transcript_exon_variant 0.32
rrl 1476540 n.2883C>G non_coding_transcript_exon_variant 0.31
rrl 1476584 n.2927C>T non_coding_transcript_exon_variant 0.4
rrl 1476585 n.2928A>G non_coding_transcript_exon_variant 0.41
rrl 1476594 n.2937C>T non_coding_transcript_exon_variant 0.44
rrl 1476603 n.2946G>A non_coding_transcript_exon_variant 0.41
rrl 1476614 n.2957A>T non_coding_transcript_exon_variant 0.44
rrl 1476616 n.2959A>G non_coding_transcript_exon_variant 0.46
rrl 1476619 n.2962C>T non_coding_transcript_exon_variant 0.44
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 0.47
rrl 1476629 n.2972C>A non_coding_transcript_exon_variant 0.49
rrl 1476630 n.2973A>G non_coding_transcript_exon_variant 0.49
rrl 1476661 n.3004A>G non_coding_transcript_exon_variant 0.24
rrl 1476665 n.3008T>G non_coding_transcript_exon_variant 0.26
rrl 1476668 n.3011C>T non_coding_transcript_exon_variant 0.26
rrl 1476675 n.3018C>G non_coding_transcript_exon_variant 0.15
fabG1 1673962 p.Asn175Asp missense_variant 0.13
rpsA 1833646 c.105T>C synonymous_variant 0.14
rpsA 1833667 c.126C>G synonymous_variant 0.17
rpsA 1833676 c.135A>G synonymous_variant 0.19
rpsA 1833685 c.144G>C synonymous_variant 0.17
rpsA 1833694 c.153G>C synonymous_variant 0.19
rpsA 1833721 c.180A>G synonymous_variant 0.15
rpsA 1833727 c.186G>C synonymous_variant 0.15
rpsA 1833734 p.Ala65Ser missense_variant 0.11
rpsA 1833742 c.201A>G synonymous_variant 0.11
rpsA 1834009 c.468C>T synonymous_variant 0.12
rpsA 1834015 c.474G>C synonymous_variant 0.19
rpsA 1834024 c.483G>C synonymous_variant 0.25
rpsA 1834030 c.489C>G synonymous_variant 0.22
rpsA 1834034 p.Ile165Val missense_variant 0.22
rpsA 1834054 c.513C>G synonymous_variant 0.23
rpsA 1834069 c.528G>C synonymous_variant 0.19
rpsA 1834177 c.636A>C synonymous_variant 1.0
rpsA 1834210 c.669C>T synonymous_variant 0.17
rpsA 1834222 c.681T>C synonymous_variant 0.18
rpsA 1834231 c.690T>C synonymous_variant 0.2
rpsA 1834240 c.699T>C synonymous_variant 0.18
rpsA 1834243 c.702G>C synonymous_variant 0.18
tlyA 1917872 c.-68T>G upstream_gene_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102350 c.693G>A synonymous_variant 0.18
katG 2154724 p.Arg463Leu missense_variant 1.0
katG 2155248 c.864C>A synonymous_variant 0.13
PPE35 2167926 p.Leu896Ser missense_variant 1.0
PPE35 2169320 p.Leu431Phe missense_variant 0.23
Rv1979c 2221939 p.Arg409Gln missense_variant 1.0
Rv1979c 2222976 c.189C>T synonymous_variant 0.12
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518601 p.Gly163Trp missense_variant 0.13
eis 2714668 c.659_664delCCGACG disruptive_inframe_deletion 0.15
folC 2746386 p.His405Asn missense_variant 0.14
ribD 2986962 p.Arg42Trp missense_variant 0.13
thyX 3067660 p.His96Asn missense_variant 0.12
thyX 3067802 c.144C>A synonymous_variant 0.18
thyX 3068036 c.-92delC upstream_gene_variant 0.15
thyA 3074064 c.407delG frameshift_variant 0.17
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087095 c.277delA frameshift_variant 0.1
fbiD 3339222 c.105C>A synonymous_variant 0.22
Rv3083 3448384 c.-120_-119insCC upstream_gene_variant 0.12
Rv3083 3449106 c.603C>T synonymous_variant 0.15
Rv3083 3449676 c.1173C>A synonymous_variant 0.15
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612813 p.Thr102Ala missense_variant 1.0
clpC1 4038163 c.2542C>A synonymous_variant 0.29
clpC1 4039541 c.1164C>G synonymous_variant 0.1
clpC1 4039562 c.1143C>G synonymous_variant 0.11
clpC1 4039568 p.Met379Ile missense_variant 0.1
clpC1 4039580 c.1125C>G synonymous_variant 0.1
clpC1 4039904 c.801A>G synonymous_variant 0.12
clpC1 4039991 c.714G>C synonymous_variant 0.1
clpC1 4040024 c.681A>G synonymous_variant 0.14
clpC1 4040033 c.672G>C synonymous_variant 0.15
clpC1 4040036 c.669C>G synonymous_variant 0.17
embC 4240424 p.Arg188Ser missense_variant 0.18
embC 4241036 c.1174C>T synonymous_variant 0.14
embC 4242423 p.Trp854* stop_gained 0.2
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243274 c.42C>A synonymous_variant 0.15
embA 4243370 c.138G>A synonymous_variant 0.13
embA 4243460 c.228C>T synonymous_variant 1.0
embA 4246192 c.2964delC frameshift_variant 0.14
embA 4246390 p.Asp1053Val missense_variant 0.12
embB 4249333 c.2820C>A synonymous_variant 0.12
aftB 4267647 p.Asp397Gly missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0
gid 4407766 p.Thr146Lys missense_variant 0.13
gid 4407927 p.Glu92Asp missense_variant 1.0