Run ID: SRR6785263
Sample name:
Date: 2024-04-15T10:39:10.641165
Number of reads: 2491233
Percentage reads mapped: 82.31
Median coverage: 58.0
Strain: lineage2.2.1
Spoligotype:
Drug-resistance: Sensitive
Lineage | Family | RDs | Frequency |
---|---|---|---|
lineage2 | East-Asian | RD105 | 0.99 |
lineage2.2.1 | East-Asian (Beijing) | RD105;RD207;RD181 | 0.99 |
lineage2.2 | East-Asian (Beijing) | RD105;RD207 | 0.98 |
Drug | Resistance | Supporting mutations | WHO confidence | Comment |
---|---|---|---|---|
rifampicin | ||||
isoniazid | ||||
ethambutol | ||||
pyrazinamide | ||||
streptomycin | ||||
fluoroquinolones | ||||
moxifloxacin | ||||
ofloxacin | ||||
levofloxacin | ||||
ciprofloxacin | ||||
aminoglycosides | ||||
amikacin | ||||
capreomycin | ||||
kanamycin | ||||
cycloserine | ||||
ethionamide | ||||
clofazimine | ||||
para-aminosalicylic_acid | ||||
delamanid | ||||
bedaquiline | ||||
linezolid |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence | Comment |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs | Confidence |
---|---|---|---|---|---|---|
dnaA | 741 | c.741T>C | synonymous_variant | 0.14 | isoniazid | Not assoc w R - Interim |
dnaA | 849 | c.849A>G | synonymous_variant | 0.15 | isoniazid | |
dnaA | 885 | c.885T>C | synonymous_variant | 0.14 | isoniazid | |
dnaA | 1245 | c.1245G>C | synonymous_variant | 0.15 | isoniazid | Not assoc w R - Interim |
dnaA | 1254 | c.1254T>C | synonymous_variant | 0.18 | isoniazid | |
dnaA | 1278 | c.1278T>C | synonymous_variant | 0.15 | isoniazid | |
gyrB | 6238 | c.999G>A | synonymous_variant | 0.15 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6242 | p.Arg335Asn | missense_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6250 | c.1011A>G | synonymous_variant | 0.16 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6256 | c.1017G>A | synonymous_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6268 | c.1029C>G | synonymous_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6280 | c.1041T>C | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6286 | c.1047T>C | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6289 | c.1050C>T | synonymous_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6292 | c.1053G>C | synonymous_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6307 | c.1068T>G | synonymous_variant | 0.15 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 6362 | c.-940T>C | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6649 | c.-653T>C | upstream_gene_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6655 | c.-647T>C | upstream_gene_variant | 0.14 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6670 | c.-632G>C | upstream_gene_variant | 0.17 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6673 | c.-629A>C | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6676 | c.-626T>G | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6700 | c.-602T>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6703 | c.-599G>C | upstream_gene_variant | 0.19 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6709 | c.-593A>G | upstream_gene_variant | 0.2 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 6712 | c.-590G>C | upstream_gene_variant | 0.21 | levofloxacin | |
moxifloxacin | ||||||
gyrB | 6728 | c.1489_1491delCTAinsTG | frameshift_variant&stop_gained | 0.17 | levofloxacin | Uncertain significance |
moxifloxacin | ||||||
gyrB | 6745 | c.1506T>G | synonymous_variant | 0.13 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrB | 6775 | c.1536G>C | synonymous_variant | 0.13 | levofloxacin | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
gyrA | 7078 | c.-224A>C | upstream_gene_variant | 0.15 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7084 | c.-218A>G | upstream_gene_variant | 0.16 | levofloxacin | |
moxifloxacin | ||||||
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 7585 | p.Ser95Thr | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
gyrA | 9304 | p.Gly668Asp | missense_variant | 1.0 | levofloxacin | Not assoc w R |
moxifloxacin | Not assoc w R | |||||
fgd1 | 491742 | c.960T>C | synonymous_variant | 1.0 | clofazimine | Not assoc w R |
pretomanid | ||||||
delamanid | Not assoc w R - Interim | |||||
mshA | 575907 | p.Ala187Val | missense_variant | 0.94 | ethionamide | Not assoc w R |
isoniazid | Not assoc w R | |||||
ccsA | 620310 | c.420C>T | synonymous_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620317 | c.427_429delGTCinsCG | frameshift_variant&missense_variant | 0.18 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620340 | c.450C>G | synonymous_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620346 | c.456C>G | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620362 | p.Ala158Thr | missense_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620367 | c.477T>C | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620373 | c.483C>G | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620376 | c.486G>C | synonymous_variant | 0.22 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620385 | c.495G>C | synonymous_variant | 0.21 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620388 | c.498A>G | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620389 | c.499C>T | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620412 | c.522T>C | synonymous_variant | 0.19 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620415 | c.525T>C | synonymous_variant | 0.16 | capreomycin | Not assoc w R - Interim |
amikacin | Not assoc w R - Interim | |||||
kanamycin | Not assoc w R - Interim | |||||
ccsA | 620421 | c.531G>C | synonymous_variant | 0.13 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620424 | c.534G>C | synonymous_variant | 0.16 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620460 | c.570T>G | synonymous_variant | 0.13 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
ccsA | 620625 | p.Ile245Met | missense_variant | 0.98 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Uncertain significance | |||||
Rv0565c | 657081 | c.390G>A | synonymous_variant | 0.97 | ethionamide | Not assoc w R - Interim |
Rv0565c | 657142 | p.Arg110His | missense_variant | 0.98 | ethionamide | Uncertain significance |
Rv0565c | 657671 | c.-201A>G | upstream_gene_variant | 0.14 | ethionamide | |
hadA | 732329 | p.Leu134Val | missense_variant | 0.17 | isoniazid | Uncertain significance |
hadA | 732337 | c.408G>A | synonymous_variant | 0.15 | isoniazid | |
hadA | 732378 | c.450_452dupAGA | disruptive_inframe_insertion | 0.17 | isoniazid | |
hadA | 732396 | p.Gly156Ala | missense_variant | 0.19 | isoniazid | |
hadA | 732398 | p.Ala157Thr | missense_variant | 0.19 | isoniazid | |
rpoB | 760181 | c.375T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 760184 | c.378A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 760196 | c.390C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760223 | c.417T>C | synonymous_variant | 0.15 | rifampicin | |
rpoB | 760298 | c.492G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760307 | c.501T>C | synonymous_variant | 0.14 | rifampicin | |
rpoB | 760328 | c.522G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760331 | c.525G>C | synonymous_variant | 0.18 | rifampicin | |
rpoB | 760340 | c.534G>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760361 | c.555T>C | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoB | 760370 | c.564C>G | synonymous_variant | 0.22 | rifampicin | |
rpoB | 760376 | p.Asp190Glu | missense_variant | 0.21 | rifampicin | Uncertain significance |
rpoB | 760380 | p.Thr192Leu | missense_variant | 0.19 | rifampicin | |
rpoB | 760406 | c.600G>C | synonymous_variant | 0.23 | rifampicin | |
rpoB | 760412 | c.606C>G | synonymous_variant | 0.2 | rifampicin | |
rpoB | 760424 | c.618C>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 760430 | c.624T>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 760475 | c.669A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760481 | c.675G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760484 | c.678A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 760522 | p.Ser239Asn | missense_variant | 0.16 | rifampicin | Uncertain significance |
rpoB | 760532 | c.726T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760533 | p.Val243Thr | missense_variant | 0.14 | rifampicin | |
rpoB | 760541 | c.735G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760547 | c.741G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760563 | p.Arg253Ile | missense_variant | 0.13 | rifampicin | |
rpoB | 760591 | p.Val262Ala | missense_variant | 0.21 | rifampicin | |
rpoB | 760611 | c.805T>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 760646 | c.840C>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 760661 | c.855A>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 760670 | c.864G>C | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761129 | c.1323G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761150 | c.1344A>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoB | 761153 | c.1347G>C | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761165 | c.1359G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoB | 761180 | c.1374A>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 761207 | c.1401C>T | synonymous_variant | 0.13 | rifampicin | |
rpoB | 761219 | c.1413G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 761249 | c.1443A>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761255 | c.1449T>G | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761261 | c.1455G>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761306 | c.1500C>G | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761312 | c.1506G>C | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761327 | c.1521A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 761330 | c.1524G>C | synonymous_variant | 0.15 | rifampicin | |
rpoB | 761354 | c.1548C>T | synonymous_variant | 0.17 | rifampicin | |
rpoB | 761360 | c.1554T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoB | 761362 | p.Ser519Thr | missense_variant | 0.16 | rifampicin | |
rpoB | 761636 | c.1830G>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 761645 | c.1839C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 761648 | c.1842T>C | synonymous_variant | 0.14 | rifampicin | |
rpoB | 761657 | c.1851C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762008 | c.2202C>T | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 762065 | c.2259T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762083 | c.2277T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762086 | c.2280G>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoB | 762329 | c.2523G>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoB | 762338 | c.2532T>C | synonymous_variant | 0.14 | rifampicin | |
rpoB | 762347 | c.2541T>C | synonymous_variant | 0.13 | rifampicin | |
rpoC | 762434 | c.-936T>C | upstream_gene_variant | 0.13 | rifampicin | |
rpoB | 762449 | c.2643C>A | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 762989 | c.-381G>C | upstream_gene_variant | 0.2 | rifampicin | |
rpoB | 762995 | c.3189G>T | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 763013 | c.-357C>G | upstream_gene_variant | 0.18 | rifampicin | |
rpoB | 763031 | c.3225T>C | synonymous_variant | 0.94 | rifampicin | Not assoc w R |
rpoB | 763115 | c.3309T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 763136 | c.3330C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763148 | c.-222G>C | upstream_gene_variant | 0.18 | rifampicin | |
rpoC | 763158 | c.-212C>T | upstream_gene_variant | 0.19 | rifampicin | |
rpoB | 763166 | c.3360A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763190 | c.-180C>T | upstream_gene_variant | 0.16 | rifampicin | |
rpoC | 763206 | c.-164_-162delAGTinsTCG | upstream_gene_variant | 0.14 | rifampicin | |
rpoB | 763214 | c.3408T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 763226 | c.-144A>G | upstream_gene_variant | 0.15 | rifampicin | |
rpoB | 763227 | c.3421C>T | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoB | 763238 | c.3432T>C | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 763253 | c.-117G>C | upstream_gene_variant | 0.15 | rifampicin | |
rpoC | 763256 | c.-114G>A | upstream_gene_variant | 0.15 | rifampicin | |
rpoC | 763456 | c.87A>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 763486 | c.117T>G | synonymous_variant | 0.15 | rifampicin | |
rpoC | 763528 | c.159G>A | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 763570 | c.201G>C | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763573 | c.204G>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 763594 | c.225C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763603 | c.234C>T | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763636 | c.267T>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 763660 | c.291T>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoC | 763675 | c.306C>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 763696 | c.327T>C | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 763702 | c.333C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 763717 | c.348T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763723 | c.354G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763732 | c.363C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763741 | c.372C>T | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763744 | c.375G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 763765 | c.396T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 763774 | c.405G>C | synonymous_variant | 0.24 | rifampicin | |
rpoC | 763807 | c.438T>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 763816 | c.447C>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 763835 | p.Ala156Met | missense_variant | 0.15 | rifampicin | |
rpoC | 763853 | p.Val162Ile | missense_variant | 0.15 | rifampicin | |
rpoC | 763858 | c.489A>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 763872 | p.Gly168Ala | missense_variant | 0.16 | rifampicin | |
rpoC | 763876 | p.Glu169Asp | missense_variant | 0.16 | rifampicin | |
rpoC | 763879 | c.510A>G | synonymous_variant | 0.14 | rifampicin | |
rpoC | 763888 | c.519G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 763891 | c.522G>C | synonymous_variant | 0.15 | rifampicin | |
rpoC | 763894 | c.525A>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 763900 | c.531G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 763936 | c.567C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763939 | c.570G>A | synonymous_variant | 0.18 | rifampicin | |
rpoC | 763942 | c.573C>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 763948 | c.579G>A | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 763949 | c.580C>A | synonymous_variant | 0.17 | rifampicin | |
rpoC | 763954 | c.585C>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764002 | c.633C>G | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764005 | c.636G>C | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764024 | c.655_657delTTGinsCC | frameshift_variant&missense_variant | 0.18 | rifampicin | |
rpoC | 764032 | p.Asp221Glu | missense_variant | 0.19 | rifampicin | |
rpoC | 764040 | p.Ser224Thr | missense_variant | 0.19 | rifampicin | |
rpoC | 764044 | c.675T>C | synonymous_variant | 0.21 | rifampicin | |
rpoC | 764059 | c.690G>T | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764083 | c.714A>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764098 | c.729A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764101 | c.732C>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764102 | p.Val245Ile | missense_variant | 0.2 | rifampicin | |
rpoC | 764112 | p.Tyr248Phe | missense_variant | 0.2 | rifampicin | |
rpoC | 764116 | c.747C>T | synonymous_variant | 0.21 | rifampicin | Not assoc w R - Interim |
rpoC | 764131 | c.762T>C | synonymous_variant | 0.2 | rifampicin | |
rpoC | 764140 | c.771C>T | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764434 | c.1065A>G | synonymous_variant | 0.18 | rifampicin | Not assoc w R - Interim |
rpoC | 764446 | c.1077T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764449 | c.1080G>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 764452 | c.1083T>C | synonymous_variant | 0.19 | rifampicin | |
rpoC | 764458 | c.1089G>C | synonymous_variant | 0.19 | rifampicin | Not assoc w R - Interim |
rpoC | 764461 | c.1092A>G | synonymous_variant | 0.2 | rifampicin | Not assoc w R - Interim |
rpoC | 764497 | c.1128A>G | synonymous_variant | 0.16 | rifampicin | Not assoc w R - Interim |
rpoC | 764510 | c.1141C>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764521 | c.1152T>C | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764527 | c.1158C>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 764536 | c.1167G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 764872 | c.1503A>G | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764932 | c.1563C>A | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
rpoC | 764935 | c.1566T>C | synonymous_variant | 0.13 | rifampicin | |
rpoC | 765553 | c.2184C>T | synonymous_variant | 0.17 | rifampicin | Not assoc w R - Interim |
rpoC | 765556 | c.2187G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 765559 | c.2190G>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 765580 | c.2211G>C | synonymous_variant | 0.16 | rifampicin | |
rpoC | 765613 | p.His748Gln | missense_variant | 0.18 | rifampicin | |
rpoC | 765835 | c.2466C>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 765994 | c.2625A>T | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoC | 766043 | p.Gln892Glu | missense_variant | 0.15 | rifampicin | |
rpoC | 766054 | c.2685C>G | synonymous_variant | 0.16 | rifampicin | |
rpoC | 766531 | c.3162G>C | synonymous_variant | 0.12 | rifampicin | |
rpoC | 766645 | p.Glu1092Asp | missense_variant | 0.83 | rifampicin | Not assoc w R |
rpoC | 766894 | c.3525T>C | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766900 | c.3531T>C | synonymous_variant | 0.18 | rifampicin | |
rpoC | 766933 | c.3564A>G | synonymous_variant | 0.17 | rifampicin | |
rpoC | 766945 | c.3576A>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776100 | p.Thr794Ile | missense_variant | 0.98 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
mmpL5 | 776182 | p.Asp767Asn | missense_variant | 0.98 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R | |||||
mmpS5 | 779615 | c.-710C>G | upstream_gene_variant | 0.96 | clofazimine | |
bedaquiline | ||||||
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 | streptomycin | Not assoc w R |
rpsL | 781728 | c.169T>C | synonymous_variant | 0.14 | streptomycin | |
rpsL | 781736 | c.177T>C | synonymous_variant | 0.13 | streptomycin | |
rpsL | 781742 | c.183C>T | synonymous_variant | 0.14 | streptomycin | |
rpsL | 781760 | c.201T>C | synonymous_variant | 0.14 | streptomycin | |
rpsL | 781772 | c.213C>A | synonymous_variant | 0.14 | streptomycin | |
rplC | 801321 | c.513C>T | synonymous_variant | 0.14 | linezolid | Not assoc w R - Interim |
rplC | 801324 | c.516T>C | synonymous_variant | 0.17 | linezolid | |
rplC | 801339 | c.531T>C | synonymous_variant | 0.13 | linezolid | |
rplC | 801341 | p.Leu178Gln | missense_variant | 0.13 | linezolid | |
rplC | 801348 | c.540T>G | synonymous_variant | 0.15 | linezolid | |
rplC | 801357 | c.549T>C | synonymous_variant | 0.14 | linezolid | |
rplC | 801367 | p.Ala187Thr | missense_variant | 0.15 | linezolid | |
rplC | 801402 | c.594T>C | synonymous_variant | 0.15 | linezolid | |
rplC | 801405 | c.597T>C | synonymous_variant | 0.15 | linezolid | |
rplC | 801423 | c.615G>C | synonymous_variant | 0.14 | linezolid | |
rplC | 801426 | c.618C>G | synonymous_variant | 0.14 | linezolid | |
rplC | 801427 | p.Met207Val | missense_variant | 0.15 | linezolid | |
rplC | 801438 | c.630T>C | synonymous_variant | 0.18 | linezolid | |
rplC | 801442 | p.Ile212Val | missense_variant | 0.16 | linezolid | |
Rv1129c | 1254562 | c.-28T>C | upstream_gene_variant | 1.0 | moxifloxacin | Not assoc w R |
levofloxacin | Not assoc w R | |||||
rifampicin | Not assoc w R | |||||
isoniazid | Not assoc w R | |||||
sigE | 1364706 | c.294G>A | synonymous_variant | 0.98 | pyrazinamide | Not assoc w R - Interim |
Rv1258c | 1406760 | c.580_581insC | frameshift_variant | 0.94 | streptomycin | Uncertain significance |
isoniazid | Uncertain significance | |||||
pyrazinamide | Uncertain significance | |||||
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 | streptomycin | |
kanamycin | ||||||
capreomycin | ||||||
amikacin | ||||||
rrl | 1473943 | n.286G>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1473986 | n.329T>C | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1473987 | n.330G>A | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1473995 | n.338G>T | non_coding_transcript_exon_variant | 0.19 | capreomycin | |
linezolid | ||||||
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 0.17 | capreomycin | Not assoc w R |
linezolid | Not assoc w R | |||||
rrl | 1474009 | n.352A>G | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1474012 | n.355C>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1474639 | n.982G>A | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1474970 | n.1313G>A | non_coding_transcript_exon_variant | 0.14 | capreomycin | |
linezolid | ||||||
rrl | 1475006 | n.1349A>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | |
linezolid | ||||||
rrl | 1475013 | n.1356G>A | non_coding_transcript_exon_variant | 0.17 | capreomycin | |
linezolid | ||||||
rrl | 1475199 | n.1542G>A | non_coding_transcript_exon_variant | 0.2 | capreomycin | |
linezolid | ||||||
rrl | 1475249 | n.1592T>C | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475252 | n.1595C>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | |
linezolid | ||||||
rrl | 1475266 | n.1609T>C | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475275 | n.1618C>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1475402 | n.1745C>T | non_coding_transcript_exon_variant | 0.13 | capreomycin | |
linezolid | ||||||
rrl | 1475419 | n.1762C>T | non_coding_transcript_exon_variant | 0.18 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475483 | n.1826C>T | non_coding_transcript_exon_variant | 0.21 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1475505 | n.1848G>A | non_coding_transcript_exon_variant | 0.22 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475599 | n.1942A>G | non_coding_transcript_exon_variant | 0.25 | capreomycin | |
linezolid | Uncertain significance | |||||
rrl | 1475608 | n.1951T>C | non_coding_transcript_exon_variant | 0.25 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1475638 | n.1981C>T | non_coding_transcript_exon_variant | 0.14 | capreomycin | |
linezolid | ||||||
rrl | 1475642 | n.1985T>C | non_coding_transcript_exon_variant | 0.16 | capreomycin | |
linezolid | ||||||
rrl | 1476224 | n.2567A>G | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476281 | n.2624T>C | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476583 | n.2926G>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476584 | n.2927C>T | non_coding_transcript_exon_variant | 0.16 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476594 | n.2937C>T | non_coding_transcript_exon_variant | 0.15 | capreomycin | Not assoc w R |
linezolid | Uncertain significance | |||||
rrl | 1476597 | n.2940G>A | non_coding_transcript_exon_variant | 0.17 | capreomycin | Uncertain significance |
linezolid | ||||||
rrl | 1476603 | n.2946G>A | non_coding_transcript_exon_variant | 0.16 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rrl | 1476608 | n.2951C>G | non_coding_transcript_exon_variant | 0.15 | capreomycin | Uncertain significance |
linezolid | Uncertain significance | |||||
rpsA | 1833811 | c.270G>T | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833838 | c.297G>C | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1833841 | c.300C>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1833847 | c.306C>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833856 | c.315A>G | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1833928 | c.387G>C | synonymous_variant | 0.2 | pyrazinamide | |
rpsA | 1833940 | c.399C>G | synonymous_variant | 0.23 | pyrazinamide | |
rpsA | 1833971 | c.430C>T | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1833979 | c.438T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834000 | c.459G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834021 | c.480C>T | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834030 | c.489C>G | synonymous_variant | 0.17 | pyrazinamide | |
rpsA | 1834096 | c.555G>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834099 | c.558C>G | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834102 | c.561T>C | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834105 | c.564C>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834108 | c.567C>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834123 | c.582C>G | synonymous_variant | 0.16 | pyrazinamide | |
rpsA | 1834177 | c.636A>C | synonymous_variant | 0.99 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834210 | c.669C>T | synonymous_variant | 0.15 | pyrazinamide | |
rpsA | 1834222 | c.681T>C | synonymous_variant | 0.14 | pyrazinamide | |
rpsA | 1834231 | c.690T>C | synonymous_variant | 0.13 | pyrazinamide | |
rpsA | 1834348 | c.807T>C | synonymous_variant | 0.15 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834366 | c.825A>G | synonymous_variant | 0.18 | pyrazinamide | Not assoc w R - Interim |
rpsA | 1834435 | c.894G>C | synonymous_variant | 0.19 | pyrazinamide | |
rpsA | 1834465 | c.924T>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834468 | c.927A>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834489 | c.948T>C | synonymous_variant | 0.31 | pyrazinamide | |
rpsA | 1834513 | c.972C>G | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834528 | c.987T>C | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834540 | c.999G>C | synonymous_variant | 0.21 | pyrazinamide | |
rpsA | 1834546 | c.1005T>C | synonymous_variant | 0.22 | pyrazinamide | |
rpsA | 1834555 | c.1014T>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834609 | c.1068T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834618 | c.1077G>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834633 | c.1092A>G | synonymous_variant | 0.24 | pyrazinamide | |
rpsA | 1834639 | c.1098T>C | synonymous_variant | 0.26 | pyrazinamide | |
rpsA | 1834654 | p.Glu371Asp | missense_variant | 0.25 | pyrazinamide | |
rpsA | 1834690 | c.1149T>C | synonymous_variant | 0.21 | pyrazinamide | |
tsnR | 1854300 | p.Leu232Pro | missense_variant | 1.0 | linezolid | Not assoc w R |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 | capreomycin | Not assoc w R |
katG | 2154724 | p.Arg463Leu | missense_variant | 0.97 | isoniazid | Not assoc w R |
PPE35 | 2167926 | p.Leu896Ser | missense_variant | 1.0 | pyrazinamide | Not assoc w R |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 | clofazimine | Not assoc w R |
bedaquiline | Not assoc w R - Interim | |||||
kasA | 2517950 | c.-165C>G | upstream_gene_variant | 0.19 | isoniazid | |
Rv2477c | 2783116 | c.927T>C | synonymous_variant | 0.13 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783665 | c.378A>G | synonymous_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783674 | c.369T>C | synonymous_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783683 | c.360A>G | synonymous_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783700 | p.Thr115Ser | missense_variant | 0.16 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783718 | c.325T>C | synonymous_variant | 0.19 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2477c | 2783719 | c.324A>G | synonymous_variant | 0.2 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
kanamycin | ||||||
rifampicin | ||||||
amikacin | ||||||
Rv2752c | 3066360 | c.-169T>C | upstream_gene_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
thyX | 3067439 | c.507A>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067445 | c.501C>G | synonymous_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067457 | c.489C>G | synonymous_variant | 0.37 | para-aminosalicylic_acid | |
thyX | 3067465 | p.Ile161Val | missense_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067475 | c.471A>G | synonymous_variant | 0.41 | para-aminosalicylic_acid | |
thyX | 3067490 | c.456C>G | synonymous_variant | 0.39 | para-aminosalicylic_acid | |
thyX | 3067493 | c.453A>G | synonymous_variant | 0.38 | para-aminosalicylic_acid | |
thyX | 3067515 | p.Ser144Thr | missense_variant | 0.33 | para-aminosalicylic_acid | |
thyX | 3067530 | p.Ala139Ser | missense_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067545 | p.Glu134Ala | missense_variant | 0.26 | para-aminosalicylic_acid | |
thyX | 3067549 | p.Thr133Ala | missense_variant | 0.22 | para-aminosalicylic_acid | |
ald | 3086788 | c.-32T>C | upstream_gene_variant | 1.0 | cycloserine | |
Rv3236c | 3612813 | p.Thr102Ala | missense_variant | 1.0 | pyrazinamide | Not assoc w R - Interim |
mtrB | 3625065 | p.Met517Leu | missense_variant | 1.0 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
lpqB | 3625687 | c.-777G>C | upstream_gene_variant | 0.15 | bedaquiline | |
rifampicin | ||||||
mtrB | 3625755 | p.Ala287Thr | missense_variant | 0.13 | bedaquiline | |
rifampicin | Uncertain significance | |||||
mtrB | 3626562 | p.Pro18Ser | missense_variant | 0.97 | bedaquiline | Uncertain significance |
rifampicin | Not assoc w R | |||||
mtrA | 3627188 | c.162A>G | synonymous_variant | 0.13 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627209 | c.-596G>A | upstream_gene_variant | 0.13 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627221 | c.129C>T | synonymous_variant | 0.13 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrA | 3627227 | c.123T>C | synonymous_variant | 0.13 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627233 | c.-620T>C | upstream_gene_variant | 0.13 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627236 | c.-623T>C | upstream_gene_variant | 0.13 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627242 | c.108C>T | synonymous_variant | 0.14 | bedaquiline | |
rifampicin | Not assoc w R - Interim | |||||
mtrB | 3627254 | c.-641C>T | upstream_gene_variant | 0.18 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627263 | c.-650C>T | upstream_gene_variant | 0.15 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627266 | c.-653A>G | upstream_gene_variant | 0.15 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627272 | c.-659G>T | upstream_gene_variant | 0.15 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627275 | c.-662G>T | upstream_gene_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627296 | c.-683T>C | upstream_gene_variant | 0.16 | bedaquiline | |
rifampicin | ||||||
mtrA | 3627299 | c.49_51delTTGinsCA | frameshift_variant&missense_variant | 0.14 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627314 | c.-701C>T | upstream_gene_variant | 0.15 | bedaquiline | |
rifampicin | ||||||
mtrB | 3627317 | c.-704T>C | upstream_gene_variant | 0.14 | bedaquiline | |
rifampicin | ||||||
rpoA | 3877704 | c.804G>C | synonymous_variant | 0.15 | rifampicin | |
rpoA | 3877743 | c.765T>C | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoA | 3877764 | c.744C>G | synonymous_variant | 0.15 | rifampicin | Not assoc w R - Interim |
rpoA | 3877770 | c.738A>G | synonymous_variant | 0.14 | rifampicin | Not assoc w R - Interim |
rpoA | 3877776 | c.732T>C | synonymous_variant | 0.13 | rifampicin | Not assoc w R - Interim |
clpC1 | 4038845 | c.1860G>C | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4038860 | c.1845G>C | synonymous_variant | 0.13 | pyrazinamide | Not assoc w R - Interim |
clpC1 | 4040291 | c.414G>C | synonymous_variant | 0.16 | pyrazinamide | |
clpC1 | 4040318 | c.387C>G | synonymous_variant | 0.17 | pyrazinamide | |
clpC1 | 4040330 | c.375C>G | synonymous_variant | 0.14 | pyrazinamide | |
clpC1 | 4040342 | c.363C>G | synonymous_variant | 0.15 | pyrazinamide | |
glpK | 4138670 | c.1086G>C | synonymous_variant | 0.13 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138681 | p.Met359Val | missense_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138695 | p.Pro354Asp | missense_variant | 0.14 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138718 | c.1038T>C | synonymous_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138721 | c.1035G>A | synonymous_variant | 0.14 | ethambutol | Not assoc w R - Interim |
moxifloxacin | Not assoc w R - Interim | |||||
streptomycin | ||||||
levofloxacin | Not assoc w R - Interim | |||||
rifampicin | Not assoc w R - Interim | |||||
isoniazid | Not assoc w R - Interim | |||||
glpK | 4138724 | c.1032A>G | synonymous_variant | 0.14 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138730 | c.1026C>G | synonymous_variant | 0.17 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
glpK | 4138757 | c.999A>G | synonymous_variant | 0.15 | ethambutol | |
moxifloxacin | ||||||
streptomycin | ||||||
levofloxacin | ||||||
rifampicin | ||||||
isoniazid | ||||||
embC | 4241107 | c.1245G>C | synonymous_variant | 0.13 | ethambutol | |
embC | 4242643 | c.2781C>T | synonymous_variant | 1.0 | ethambutol | Not assoc w R |
embA | 4243460 | c.228C>T | synonymous_variant | 0.98 | ethambutol | Not assoc w R |
aftB | 4267647 | p.Asp397Gly | missense_variant | 0.94 | ethambutol | Not assoc w R |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 | capreomycin | Not assoc w R |
amikacin | Not assoc w R | |||||
kanamycin | Not assoc w R | |||||
whiB6 | 4338732 | c.-211C>T | upstream_gene_variant | 1.0 | capreomycin | |
amikacin | ||||||
kanamycin | ||||||
gid | 4407588 | c.615A>G | synonymous_variant | 0.98 | streptomycin | Not assoc w R |
gid | 4407927 | p.Glu92Asp | missense_variant | 1.0 | streptomycin | Not assoc w R |