TB-Profiler result

Run: ERR4815556
Summary

Run ID: ERR4815556

Sample name:

Date: 01-04-2023 13:55:54

Number of reads: 824746

Percentage reads mapped: 68.62

Strain: lineage3

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage3 East-African-Indian CAS RD750 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761127 p.Ser441Ala missense_variant 0.26 rifampicin
rpoB 761196 p.Leu464Met missense_variant 0.29 rifampicin
rrs 1472644 n.799C>T non_coding_transcript_exon_variant 0.57 streptomycin
rrs 1473247 n.1402C>A non_coding_transcript_exon_variant 0.82 kanamycin, capreomycin, aminoglycosides, amikacin
rrs 1473329 n.1484G>T non_coding_transcript_exon_variant 0.57 kanamycin, capreomycin, aminoglycosides, amikacin
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 1.0
rpoB 759746 c.-61C>T upstream_gene_variant 1.0
rpoB 760982 c.1176G>C synonymous_variant 0.1
rpoB 760988 c.1182C>G synonymous_variant 0.11
rpoB 760991 c.1185G>C synonymous_variant 0.11
rpoB 761015 c.1209G>C synonymous_variant 0.19
rpoB 761027 c.1221A>G synonymous_variant 0.18
rpoB 761030 c.1224G>C synonymous_variant 0.19
rpoB 761036 c.1230G>C synonymous_variant 0.18
rpoB 761037 c.1231T>C synonymous_variant 0.18
rpoB 761051 c.1245G>T synonymous_variant 0.21
rpoB 761054 c.1248G>C synonymous_variant 0.23
rpoB 761060 c.1254C>G synonymous_variant 0.23
rpoB 761084 c.1278C>A synonymous_variant 0.21
rpoB 761088 c.1282_1283delAGinsTC synonymous_variant 0.21
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.21
rpoB 761102 c.1296A>G synonymous_variant 0.24
rpoB 761126 c.1320G>C synonymous_variant 0.26
rpoB 761132 c.1326G>T synonymous_variant 0.26
rpoB 761133 c.1327T>C synonymous_variant 0.26
rpoB 761150 c.1344A>C synonymous_variant 0.31
rpoB 761156 c.1350G>C synonymous_variant 0.29
rpoB 761165 c.1359G>C synonymous_variant 0.26
rpoB 761171 c.1365C>T synonymous_variant 0.28
rpoB 761174 c.1368T>C synonymous_variant 0.28
rpoB 761177 c.1371G>C synonymous_variant 0.29
rpoB 761180 c.1374A>G synonymous_variant 0.29
rpoB 761183 c.1377T>C synonymous_variant 0.32
rpoB 761186 p.Glu460Asp missense_variant 0.3
rpoB 761192 c.1386C>G synonymous_variant 0.3
rpoB 761195 c.1389G>C synonymous_variant 0.3
rpoB 761207 c.1401C>T synonymous_variant 0.3
rpoB 761213 c.1407G>C synonymous_variant 0.29
rpoB 761219 c.1413G>C synonymous_variant 0.35
rpoB 761234 c.1428G>C synonymous_variant 0.3
rpoB 761249 c.1443A>G synonymous_variant 0.29
rpoB 761261 c.1455G>C synonymous_variant 0.19
rpoB 761262 p.Pro486Ser missense_variant 0.19
rpoB 762218 c.2412T>C synonymous_variant 0.12
rpoB 762233 c.2427G>T synonymous_variant 0.12
rpoB 762236 c.2430G>C synonymous_variant 0.12
rpoB 762254 c.2448T>C synonymous_variant 0.11
rpoC 762434 c.-936T>G upstream_gene_variant 1.0
rpoB 762849 p.Tyr1015Asp missense_variant 0.12
rpoB 762858 p.Thr1018Ser missense_variant 0.13
rpoC 762863 c.-507T>G upstream_gene_variant 0.13
rpoB 762870 p.Met1022Gln missense_variant 0.13
rpoB 762879 p.Met1025Leu missense_variant 0.12
rpoC 762887 c.-483G>C upstream_gene_variant 0.25
rpoC 762929 c.-441G>T upstream_gene_variant 0.24
rpoC 762938 c.-432G>C upstream_gene_variant 0.27
rpoC 762980 c.-390T>C upstream_gene_variant 0.23
rpoC 762983 c.-387C>T upstream_gene_variant 0.19
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763456 c.87A>G synonymous_variant 0.12
rpoC 763465 c.96G>A synonymous_variant 0.14
rpoC 763468 c.99G>C synonymous_variant 0.14
rpoC 763486 c.117T>C synonymous_variant 0.23
rpoC 763492 c.123G>C synonymous_variant 0.24
rpoC 763505 c.136C>T synonymous_variant 0.28
rpoC 763528 c.159G>T synonymous_variant 0.31
rpoC 763531 c.162G>C synonymous_variant 0.31
rpoC 763534 c.165T>C synonymous_variant 0.3
rpoC 763537 c.168C>G synonymous_variant 0.33
rpoC 763546 c.177A>G synonymous_variant 0.33
rpoC 763570 c.201G>C synonymous_variant 0.36
rpoC 763578 p.Phe70Tyr missense_variant 0.38
rpoC 763609 c.240C>G synonymous_variant 0.41
rpoC 763615 c.246G>C synonymous_variant 0.44
rpoC 763618 c.249C>G synonymous_variant 0.45
rpoC 763621 c.252C>T synonymous_variant 0.46
rpoC 763642 c.273G>C synonymous_variant 0.42
rpoC 763660 c.291T>C synonymous_variant 0.43
rpoC 763666 c.297G>T synonymous_variant 0.43
rpoC 763672 c.303C>G synonymous_variant 0.4
rpoC 763696 c.327T>C synonymous_variant 0.33
rpoC 763699 c.330G>T synonymous_variant 0.33
rpoC 763708 c.339G>C synonymous_variant 0.31
rpoC 763709 c.340C>T synonymous_variant 0.31
rpoC 763714 c.345G>C synonymous_variant 0.31
rpoC 763717 c.348T>C synonymous_variant 0.31
rpoC 763729 c.360G>C synonymous_variant 0.29
rpoC 763732 c.363C>G synonymous_variant 0.29
rpoC 763735 c.366G>C synonymous_variant 0.28
rpoC 763744 c.375G>C synonymous_variant 0.27
rpoC 763751 p.Ile128Val missense_variant 0.21
rpoC 763765 c.396T>G synonymous_variant 0.14
rpoC 763768 c.399C>G synonymous_variant 0.14
rpoC 763772 p.Val135Met missense_variant 0.1
rpoC 764286 p.Gly306Asp missense_variant 0.18
rpoC 764297 p.Met310Leu missense_variant 0.17
rpoC 764308 c.939G>C synonymous_variant 0.27
rpoC 764311 c.942C>G synonymous_variant 0.27
rpoC 764320 c.951C>T synonymous_variant 0.25
rpoC 764347 c.978G>C synonymous_variant 0.26
rpoC 764359 c.990C>G synonymous_variant 0.35
rpoC 764365 c.996C>T synonymous_variant 0.38
rpoC 764377 c.1008C>G synonymous_variant 0.41
rpoC 764380 c.1011G>C synonymous_variant 0.42
rpoC 764387 c.1018_1020delTTGinsCTC synonymous_variant 0.42
rpoC 764398 c.1029G>C synonymous_variant 0.4
rpoC 764404 c.1035C>T synonymous_variant 0.43
rpoC 764405 c.1036A>C synonymous_variant 0.44
rpoC 764428 c.1059G>C synonymous_variant 0.48
rpoC 764434 c.1065A>G synonymous_variant 0.43
rpoC 764435 c.1066_1068delAGGinsCGT synonymous_variant 0.41
rpoC 764441 p.Ile358Leu missense_variant 0.42
rpoC 764446 c.1077T>C synonymous_variant 0.41
rpoC 764449 c.1080G>C synonymous_variant 0.39
rpoC 764455 c.1086G>C synonymous_variant 0.39
rpoC 764458 c.1089G>C synonymous_variant 0.39
rpoC 764461 c.1092A>G synonymous_variant 0.39
rpoC 764470 c.1101C>G synonymous_variant 0.42
rpoC 764485 c.1116G>C synonymous_variant 0.46
rpoC 764497 c.1128A>G synonymous_variant 0.49
rpoC 764498 p.Ser377Ala missense_variant 0.55
rpoC 764507 p.Ala380Ser missense_variant 0.54
rpoC 764521 c.1152T>C synonymous_variant 0.43
rpoC 764524 c.1155C>T synonymous_variant 0.41
rpoC 764536 c.1167G>T synonymous_variant 0.42
rpoC 764545 c.1176C>G synonymous_variant 0.46
rpoC 764548 c.1179G>T synonymous_variant 0.5
rpoC 764561 p.Pro398Ala missense_variant 0.43
rpoC 764566 c.1197C>G synonymous_variant 0.43
rpoC 764572 c.1203G>C synonymous_variant 0.41
rpoC 764575 c.1206T>G synonymous_variant 0.41
rpoC 764581 c.1212T>C synonymous_variant 0.39
rpoC 764582 p.Leu405Met missense_variant 0.39
rpoC 764602 c.1233C>A synonymous_variant 0.48
rpoC 764605 c.1236G>C synonymous_variant 0.5
rpoC 764611 c.1242G>C synonymous_variant 0.52
rpoC 764623 c.1254C>G synonymous_variant 0.47
rpoC 764632 c.1263T>C synonymous_variant 0.42
rpoC 764635 c.1266C>G synonymous_variant 0.42
rpoC 764644 c.1275G>C synonymous_variant 0.34
rpoC 764647 c.1278C>T synonymous_variant 0.36
rpoC 764650 c.1281G>T synonymous_variant 0.34
rpoC 764653 c.1284G>C synonymous_variant 0.33
rpoC 764656 c.1287C>G synonymous_variant 0.36
rpoC 764665 c.1296C>G synonymous_variant 0.39
rpoC 764668 c.1299C>T synonymous_variant 0.41
rpoC 764677 c.1308C>G synonymous_variant 0.51
rpoC 764706 p.Leu446Gln missense_variant 0.44
rpoC 764746 c.1377G>C synonymous_variant 0.44
rpoC 764758 c.1389C>G synonymous_variant 0.41
rpoC 764764 c.1395T>C synonymous_variant 0.41
rpoC 764767 c.1398G>T synonymous_variant 0.4
rpoC 764780 c.1411_1412delAGinsTC synonymous_variant 0.4
rpoC 764804 p.Gln479Tyr missense_variant 0.36
rpoC 764809 c.1440C>T synonymous_variant 0.34
rpoC 764815 c.1446A>G synonymous_variant 0.33
rpoC 764824 c.1455T>C synonymous_variant 0.29
rpoC 764830 c.1461C>G synonymous_variant 0.23
rpoC 764843 p.Ala492Thr missense_variant 0.19
rpoC 764858 c.1489T>C synonymous_variant 0.22
rpoC 764869 c.1500C>T synonymous_variant 0.19
rpoC 764872 c.1503A>G synonymous_variant 0.19
rpoC 764887 c.1518G>T synonymous_variant 0.11
rpoC 764893 c.1524T>C synonymous_variant 0.11
rpoC 764968 c.1599T>C synonymous_variant 0.14
rpoC 764971 c.1602C>G synonymous_variant 0.15
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472106 n.261G>A non_coding_transcript_exon_variant 0.4
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.4
rrs 1472112 n.267C>T non_coding_transcript_exon_variant 0.5
rrs 1472113 n.268T>C non_coding_transcript_exon_variant 0.5
rrs 1472150 n.305T>A non_coding_transcript_exon_variant 0.62
rrs 1472172 n.327T>C non_coding_transcript_exon_variant 0.62
rrs 1472225 n.380C>A non_coding_transcript_exon_variant 0.83
rrs 1472225 n.380C>G non_coding_transcript_exon_variant 0.86
rrs 1472251 n.406G>A non_coding_transcript_exon_variant 0.92
rrs 1472286 n.441C>A non_coding_transcript_exon_variant 0.71
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 0.67
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 0.8
rrs 1472290 n.445C>G non_coding_transcript_exon_variant 0.8
rrs 1472293 n.448C>A non_coding_transcript_exon_variant 0.89
rrs 1472297 n.453_465delGTCCGGGTTCTCT non_coding_transcript_exon_variant 0.89
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 0.8
rrs 1472324 n.479G>C non_coding_transcript_exon_variant 0.8
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 0.73
rrs 1472338 n.493A>G non_coding_transcript_exon_variant 0.73
rrs 1472344 n.499C>T non_coding_transcript_exon_variant 0.73
rrs 1472379 n.534T>C non_coding_transcript_exon_variant 0.44
rrs 1472382 n.537G>A non_coding_transcript_exon_variant 0.44
rrs 1472530 n.685G>A non_coding_transcript_exon_variant 0.67
rrs 1472558 n.713G>A non_coding_transcript_exon_variant 0.67
rrs 1472569 n.724G>A non_coding_transcript_exon_variant 0.5
rrs 1472581 n.736A>T non_coding_transcript_exon_variant 0.6
rrs 1472584 n.739A>T non_coding_transcript_exon_variant 0.6
rrs 1472607 n.762G>A non_coding_transcript_exon_variant 0.6
rrs 1472655 n.810G>T non_coding_transcript_exon_variant 0.6
rrs 1472660 n.815T>C non_coding_transcript_exon_variant 0.6
rrs 1472673 n.828T>G non_coding_transcript_exon_variant 0.5
rrs 1472674 n.829T>A non_coding_transcript_exon_variant 0.5
rrs 1472675 n.830T>A non_coding_transcript_exon_variant 0.5
rrs 1472677 n.832C>A non_coding_transcript_exon_variant 0.5
rrs 1472692 n.847T>C non_coding_transcript_exon_variant 0.5
rrs 1472714 n.869A>G non_coding_transcript_exon_variant 0.67
rrs 1472790 n.945T>C non_coding_transcript_exon_variant 0.4
rrs 1472824 n.979T>A non_coding_transcript_exon_variant 0.4
rrs 1472825 n.980G>A non_coding_transcript_exon_variant 0.4
rrs 1472828 n.983T>C non_coding_transcript_exon_variant 0.4
rrs 1472836 n.991G>A non_coding_transcript_exon_variant 0.4
rrs 1472840 n.995A>C non_coding_transcript_exon_variant 0.4
rrs 1472845 n.1000G>C non_coding_transcript_exon_variant 0.4
rrs 1472846 n.1001C>G non_coding_transcript_exon_variant 0.4
rrs 1472848 n.1003T>G non_coding_transcript_exon_variant 0.4
rrs 1472850 n.1005T>C non_coding_transcript_exon_variant 0.4
rrs 1472857 n.1012A>G non_coding_transcript_exon_variant 0.4
rrs 1472859 n.1014G>T non_coding_transcript_exon_variant 0.4
rrs 1472861 n.1016G>T non_coding_transcript_exon_variant 0.4
rrs 1472863 n.1020_1021dupCC non_coding_transcript_exon_variant 0.5
rrs 1472875 n.1030T>G non_coding_transcript_exon_variant 0.6
rrs 1472880 n.1035G>A non_coding_transcript_exon_variant 0.82
rrs 1472895 n.1050C>T non_coding_transcript_exon_variant 0.9
rrs 1472952 n.1107T>C non_coding_transcript_exon_variant 0.92
rrs 1472955 n.1110C>T non_coding_transcript_exon_variant 0.92
rrs 1472956 n.1111T>C non_coding_transcript_exon_variant 0.92
rrs 1472957 n.1112C>T non_coding_transcript_exon_variant 0.92
rrs 1472973 n.1128A>G non_coding_transcript_exon_variant 0.92
rrs 1472987 n.1142G>A non_coding_transcript_exon_variant 0.92
rrs 1472989 n.1144G>A non_coding_transcript_exon_variant 0.92
rrs 1472990 n.1145A>G non_coding_transcript_exon_variant 0.92
rrs 1473022 n.1177G>A non_coding_transcript_exon_variant 0.47
rrs 1473035 n.1190G>A non_coding_transcript_exon_variant 0.89
rrs 1473055 n.1210C>T non_coding_transcript_exon_variant 0.91
rrs 1473056 n.1211A>T non_coding_transcript_exon_variant 0.91
rrs 1473066 n.1221A>G non_coding_transcript_exon_variant 0.92
rrs 1473082 n.1237G>A non_coding_transcript_exon_variant 0.93
rrs 1473089 n.1244A>T non_coding_transcript_exon_variant 0.94
rrs 1473093 n.1248C>T non_coding_transcript_exon_variant 0.95
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 0.95
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 0.95
rrs 1473115 n.1270G>T non_coding_transcript_exon_variant 0.95
rrs 1473121 n.1276T>C non_coding_transcript_exon_variant 0.91
rrs 1473122 n.1277T>A non_coding_transcript_exon_variant 0.91
rrs 1473129 n.1284C>T non_coding_transcript_exon_variant 0.91
rrs 1473147 n.1302G>T non_coding_transcript_exon_variant 0.92
rrs 1473164 n.1319C>A non_coding_transcript_exon_variant 0.89
rrs 1473252 n.1407T>C non_coding_transcript_exon_variant 0.8
rrs 1473259 n.1414C>T non_coding_transcript_exon_variant 0.8
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 0.8
rrs 1473290 n.1445C>T non_coding_transcript_exon_variant 0.73
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 0.73
rrs 1473315 n.1470T>C non_coding_transcript_exon_variant 0.62
rrs 1473316 n.1471C>T non_coding_transcript_exon_variant 0.62
rrl 1474488 n.831G>T non_coding_transcript_exon_variant 1.0
rrl 1474498 n.841G>T non_coding_transcript_exon_variant 1.0
rrl 1474505 n.848C>G non_coding_transcript_exon_variant 1.0
rrl 1474516 n.859C>A non_coding_transcript_exon_variant 1.0
rrl 1474529 n.872A>C non_coding_transcript_exon_variant 1.0
rrl 1474530 n.873G>A non_coding_transcript_exon_variant 1.0
rrl 1474537 n.880G>A non_coding_transcript_exon_variant 0.8
rrl 1474539 n.882C>T non_coding_transcript_exon_variant 0.8
rrl 1474540 n.883T>G non_coding_transcript_exon_variant 0.8
rrl 1474777 n.1120T>C non_coding_transcript_exon_variant 0.75
rrl 1474779 n.1122G>A non_coding_transcript_exon_variant 0.75
rrl 1474780 n.1123C>T non_coding_transcript_exon_variant 0.75
rrl 1474782 n.1125G>A non_coding_transcript_exon_variant 0.75
rrl 1474783 n.1126G>A non_coding_transcript_exon_variant 0.75
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.75
rrl 1474823 n.1166C>G non_coding_transcript_exon_variant 0.75
rrl 1474827 n.1170C>T non_coding_transcript_exon_variant 0.75
rrl 1474830 n.1173A>T non_coding_transcript_exon_variant 0.75
rrl 1474831 n.1174A>T non_coding_transcript_exon_variant 0.75
rrl 1475672 n.2015C>T non_coding_transcript_exon_variant 1.0
rrl 1475673 n.2016T>C non_coding_transcript_exon_variant 1.0
rrl 1475699 n.2042C>T non_coding_transcript_exon_variant 1.0
rrl 1475722 n.2065G>T non_coding_transcript_exon_variant 1.0
rrl 1475753 n.2096C>T non_coding_transcript_exon_variant 1.0
rrl 1475757 n.2100_2101insG non_coding_transcript_exon_variant 1.0
rrl 1475760 n.2105_2106delGC non_coding_transcript_exon_variant 1.0
rrl 1475764 n.2107A>T non_coding_transcript_exon_variant 1.0
rrl 1475765 n.2108A>T non_coding_transcript_exon_variant 1.0
rrl 1475769 n.2112_2113insC non_coding_transcript_exon_variant 1.0
rrl 1475778 n.2121G>A non_coding_transcript_exon_variant 0.82
rrl 1475869 n.2212C>A non_coding_transcript_exon_variant 1.0
rrl 1475881 n.2224T>C non_coding_transcript_exon_variant 1.0
rrl 1475883 n.2226A>T non_coding_transcript_exon_variant 1.0
rrl 1475898 n.2241A>G non_coding_transcript_exon_variant 1.0
rrl 1475899 n.2242G>A non_coding_transcript_exon_variant 1.0
rrl 1475916 n.2259C>G non_coding_transcript_exon_variant 1.0
rrl 1475937 n.2280A>T non_coding_transcript_exon_variant 1.0
rrl 1475943 n.2286G>A non_coding_transcript_exon_variant 1.0
rrl 1475952 n.2295A>G non_coding_transcript_exon_variant 1.0
rrl 1475963 n.2306G>A non_coding_transcript_exon_variant 1.0
rrl 1475970 n.2313C>T non_coding_transcript_exon_variant 1.0
rrl 1475975 n.2318C>T non_coding_transcript_exon_variant 1.0
rrl 1475977 n.2320A>G non_coding_transcript_exon_variant 1.0
rrl 1475978 n.2321C>T non_coding_transcript_exon_variant 1.0
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0
rrl 1475997 n.2340A>G non_coding_transcript_exon_variant 1.0
rrl 1475998 n.2341C>T non_coding_transcript_exon_variant 1.0
rrl 1476001 n.2344T>C non_coding_transcript_exon_variant 1.0
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 0.67
rrl 1476245 n.2588C>T non_coding_transcript_exon_variant 0.67
rrl 1476250 n.2593C>G non_coding_transcript_exon_variant 0.67
rrl 1476252 n.2595T>G non_coding_transcript_exon_variant 0.67
rrl 1476256 n.2599A>G non_coding_transcript_exon_variant 0.67
rrl 1476257 n.2600G>C non_coding_transcript_exon_variant 0.67
rrl 1476260 n.2603A>G non_coding_transcript_exon_variant 0.67
rrl 1476337 n.2680C>T non_coding_transcript_exon_variant 0.83
rrl 1476359 n.2702C>G non_coding_transcript_exon_variant 1.0
rrl 1476381 n.2724G>C non_coding_transcript_exon_variant 0.92
rrl 1476428 n.2771C>T non_coding_transcript_exon_variant 0.92
rrl 1476429 n.2772A>T non_coding_transcript_exon_variant 0.92
rrl 1476466 n.2809C>T non_coding_transcript_exon_variant 0.86
rrl 1476481 n.2824T>C non_coding_transcript_exon_variant 0.86
rrl 1476506 n.2849T>C non_coding_transcript_exon_variant 0.5
rrl 1476515 n.2858C>T non_coding_transcript_exon_variant 0.33
rpsA 1833928 c.387G>C synonymous_variant 0.1
rpsA 1833952 c.411C>T synonymous_variant 0.13
rpsA 1833970 c.429G>C synonymous_variant 0.15
rpsA 1833979 c.438T>C synonymous_variant 0.16
rpsA 1833988 c.447C>G synonymous_variant 0.11
rpsA 1833994 c.453G>C synonymous_variant 0.11
rpsA 1833997 c.456G>C synonymous_variant 0.11
rpsA 1834003 c.462G>A synonymous_variant 0.1
rpsA 1834009 c.468C>T synonymous_variant 0.1
rpsA 1834012 c.471G>C synonymous_variant 0.1
rpsA 1834015 c.474G>C synonymous_variant 0.14
rpsA 1834024 c.483G>C synonymous_variant 0.11
rpsA 1834025 p.Gln162Ala missense_variant 0.11
rpsA 1834030 c.489C>G synonymous_variant 0.14
rpsA 1834040 p.Lys167Gln missense_variant 0.12
rpsA 1834043 p.Glu168Gln missense_variant 0.11
rpsA 1834046 p.Ile169Leu missense_variant 0.11
rpsA 1834210 c.669C>T synonymous_variant 0.18
rpsA 1834219 c.678C>G synonymous_variant 0.19
rpsA 1834222 c.681T>C synonymous_variant 0.19
rpsA 1834225 c.684C>G synonymous_variant 0.19
rpsA 1834228 c.687C>T synonymous_variant 0.19
rpsA 1834231 c.690T>C synonymous_variant 0.21
rpsA 1834240 c.699T>C synonymous_variant 0.21
rpsA 1834243 c.702G>C synonymous_variant 0.21
rpsA 1834249 c.708T>C synonymous_variant 0.24
rpsA 1834261 c.720A>G synonymous_variant 0.22
rpsA 1834264 c.723G>C synonymous_variant 0.19
rpsA 1834285 c.744G>C synonymous_variant 0.23
rpsA 1834294 c.753G>C synonymous_variant 0.24
rpsA 1834298 p.Gln253Glu missense_variant 0.23
rpsA 1834307 p.Asp256Gln missense_variant 0.21
rpsA 1834312 c.771G>A synonymous_variant 0.21
rpsA 1834321 c.780C>G synonymous_variant 0.2
rpsA 1834327 c.786G>C synonymous_variant 0.21
rpsA 1834330 c.789C>G synonymous_variant 0.21
rpsA 1834336 c.795C>G synonymous_variant 0.15
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
PPE35 2167926 p.Leu896Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289047 c.195C>T synonymous_variant 1.0
pncA 2289365 c.-125delC upstream_gene_variant 1.0
ahpC 2726105 c.-88G>A upstream_gene_variant 1.0
ahpC 2726350 p.Trp53Leu missense_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3642759 p.Arg409Ser missense_variant 1.0
clpC1 4039694 c.1011G>C synonymous_variant 0.13
clpC1 4039724 c.981A>G synonymous_variant 0.15
clpC1 4039730 c.975C>G synonymous_variant 0.21
clpC1 4039733 c.972G>C synonymous_variant 0.18
clpC1 4039748 c.957G>C synonymous_variant 0.23
clpC1 4039751 c.954A>G synonymous_variant 0.24
clpC1 4039757 c.948A>G synonymous_variant 0.22
clpC1 4039766 c.939T>C synonymous_variant 0.24
clpC1 4039769 c.936C>G synonymous_variant 0.24
clpC1 4039773 p.Lys311Met missense_variant 0.24
clpC1 4039775 c.930G>C synonymous_variant 0.24
clpC1 4039778 c.927A>G synonymous_variant 0.24
clpC1 4039781 c.924G>C synonymous_variant 0.24
clpC1 4039817 c.888A>T synonymous_variant 0.25
clpC1 4039820 c.885T>C synonymous_variant 0.25
clpC1 4039826 c.879C>G synonymous_variant 0.26
clpC1 4039829 c.874_876delTTGinsCTC synonymous_variant 0.25
clpC1 4039838 p.Leu289Ile missense_variant 0.26
clpC1 4039850 c.855T>C synonymous_variant 0.33
clpC1 4039865 c.840T>G synonymous_variant 0.37
clpC1 4039875 p.Asn277Arg missense_variant 0.28
clpC1 4039898 c.807C>G synonymous_variant 0.22
clpC1 4039904 c.801A>G synonymous_variant 0.24
clpC1 4039928 c.775_777delAGCinsTCT synonymous_variant 0.35
clpC1 4039943 c.762G>C synonymous_variant 0.33
clpC1 4039946 c.759A>C synonymous_variant 0.3
clpC1 4039949 c.756G>C synonymous_variant 0.3
clpC1 4039952 c.753T>C synonymous_variant 0.3
clpC1 4039979 c.726C>G synonymous_variant 0.21
clpC1 4039982 c.723G>C synonymous_variant 0.2
clpC1 4039988 c.717C>G synonymous_variant 0.22
clpC1 4039991 c.714G>C synonymous_variant 0.21
clpC1 4039994 p.Glu237Asp missense_variant 0.21
clpC1 4039997 c.708C>A synonymous_variant 0.2
clpC1 4040001 p.His235Arg missense_variant 0.19
clpC1 4040003 c.702G>C synonymous_variant 0.19
clpC1 4040018 c.687G>C synonymous_variant 0.17
clpC1 4040021 c.684A>C synonymous_variant 0.17
clpC1 4040024 c.681A>G synonymous_variant 0.21
clpC1 4040027 c.678C>G synonymous_variant 0.22
clpC1 4040030 c.675C>G synonymous_variant 0.21
clpC1 4040033 c.672G>C synonymous_variant 0.24
clpC1 4040045 c.660C>G synonymous_variant 0.2
embC 4242075 p.Arg738Gln missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407588 c.615A>G synonymous_variant 1.0