Rv1221 - c.324T>C
Drug resistance types
35 Sensitive
16 RR-TB
95 HR-TB
42 MDR-TB
3 Pre-XDR-TB
1 XDR-TB
57 Other
lineage Counts
| lineage | Count |
|---|---|
| lineage2.2.1 | 7 |
| lineage4.9 | 74 |
| La3;lineage4.9 | 8 |
| M.canetti;lineage2.1;lineage4.3.1;lineage4.9 | 1 |
| La3;M.canetti;lineage2.1;lineage4.9 | 12 |
| lineage2.2.1.1 | 2 |
| La1.7;lineage4.9 | 10 |
| lineage2.1;lineage4.1.1.1;lineage6.3 | 2 |
| M.canetti;lineage2.1;lineage4.9 | 21 |
| lineage4.1.2.1 | 2 |
| lineage4.9;lineage7 | 3 |
| La1.7;M.canetti;lineage4.9 | 3 |
| lineage2.1;lineage4.9;lineage7 | 1 |
| La3;M.canetti;lineage2.1;lineage4.9;lineage6.3 | 4 |
| lineage4.9;lineage6.3 | 1 |
| La1.8.1 | 2 |
| M.canetti;lineage2.1;lineage4.9;lineage6.3 | 6 |
| La3;lineage4.1.2.1;lineage4.2.1;lineage4.5;lineage4.9;lineage6.1.1;lineage6.3.2 | 1 |
| La3;M.canetti;lineage4.9 | 2 |
| La1.7.1;M.canetti;lineage4.2;lineage4.6.4;lineage4.9;lineage6.2;lineage6.3 | 2 |
| La2;lineage4.9 | 2 |
| lineage2.1;lineage4.9 | 5 |
| La1.6;La3;lineage4.6.4;lineage4.9 | 1 |
| M.canetti;lineage2.1;lineage4.3.1;lineage4.9;lineage6.3 | 4 |
| M.canetti;lineage4.3.1;lineage4.9 | 1 |
| La1.6;M.canetti;lineage4.8.1;lineage4.9;lineage6.3 | 1 |
| lineage4.3.4.2.1 | 2 |
| lineage3 | 5 |
| lineage4 | 2 |
| La3;M.canetti;lineage2.1;lineage4.3.1;lineage4.9;lineage6.3 | 2 |
| M.canetti;lineage2.1;lineage4.1.4;lineage4.3.1;lineage4.9 | 1 |
| La1.6;La3;lineage4.6.4;lineage4.8.1;lineage4.9 | 1 |
| lineage2.1;lineage2.2;lineage6.3 | 1 |
| lineage1.1 | 1 |
| La3;M.canetti;lineage3.1 | 1 |
| La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.8.1;lineage4.9 | 4 |
| M.canetti;lineage2.1;lineage3 | 1 |
| lineage1.1.1 | 1 |
| lineage4.6.3;lineage4.9 | 2 |
| lineage4.3.2;lineage4.9 | 1 |
| La3;M.canetti;lineage4.8;lineage4.9 | 1 |
| lineage3.1;lineage9 | 1 |
| La1.7 | 1 |
| lineage2.1;lineage4.9;lineage6.3 | 1 |
| lineage2.2 | 1 |
| lineage4.3.4 | 1 |
| La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.9 | 1 |
| La2;lineage2.2 | 1 |
| La3;M.canetti;lineage2.1;lineage3.1 | 1 |
| lineage4.1.2 | 1 |
| La1.6;La3;lineage4.9 | 1 |
| lineage4.3.3 | 2 |
| lineage3.1.2.2 | 1 |
| La1.6;La3;M.canetti;lineage2.1;lineage4.9 | 1 |
| lineage4.1.3 | 2 |
| lineage4.2.1 | 1 |
| M.canetti;lineage4.9 | 2 |
| lineage4.8.1;lineage4.9;lineage6.1.3;lineage6.3 | 1 |
| M.canetti;lineage2.1 | 1 |
| La1.7.1 | 1 |
| M.canetti;lineage4.1.1.3;lineage6.3;lineage8 | 1 |
| 2 | |
| M.canetti;lineage2.1;lineage4.9;lineage6.3;lineage8 | 1 |
| M.canetti;lineage2.1;lineage4.1.4;lineage4.9 | 1 |
| La1.6;La3;M.canetti;lineage4.6.4;lineage4.9 | 1 |
| La1.6;La3;M.canetti;lineage4.8.1;lineage4.9 | 1 |
| La3;lineage4 | 1 |
| La1.7.1;M.canetti;lineage4.2;lineage6.2;lineage6.3 | 1 |
| La3;M.canetti;lineage2.1;lineage4.1.4;lineage4.9;lineage6.3 | 1 |
| M.canetti;lineage2.1;lineage4.1.4;lineage4.9;lineage6.3 | 1 |
| lineage4.8 | 1 |
| lineage4.1.1.3 | 1 |
| lineage4.9;lineage9 | 2 |
| lineage4.3.2.1 | 1 |
| M.canetti;lineage2.1;lineage4.1.2.1 | 1 |
| La2;lineage4.9;lineage9 | 1 |
| La1.7.1;lineage4.9 | 1 |
| M.canetti;lineage2.1;lineage6.3 | 1 |
| La1;lineage4.9 | 1 |
| La1.7.1;M.canetti;lineage4.2;lineage4.9;lineage6.2;lineage6.3 | 1 |
| lineage4.4.1.2 | 1 |
spoligotype Counts
| spoligotype | Count |
|---|---|
| None | 249 |
Geographic prevalence
Country level data for this variant is available for 0 isolates.
Statisctical support
Not enough data to calculate support.
Samples
| ID | Drug resistance | Lineage | Country iso2 | SRR5341465 | Pre-XDR-TB | lineage2.2.1 | None | SRR6044835 | Other | lineage4.9 | None | ERR7821163 | Other | lineage2.2.1 | None | ERR3283057 | Sensitive | La3;lineage4.9 | None | SRR3675320 | MDR-TB | M.canetti;lineage2.1;lineage4.3.1;lineage4.9 | None | ERR323033 | MDR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | SRR1183106 | RR-TB | lineage2.2.1.1 | None | ERR4796929 | Sensitive | lineage4.9 | None | ERR323038 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | SRR1183965 | Sensitive | lineage4.9 | None | ERR176560 | HR-TB | La1.7;lineage4.9 | None | SRR6325442 | HR-TB | lineage2.1;lineage4.1.1.1;lineage6.3 | None | ERR473314 | HR-TB | M.canetti;lineage2.1;lineage4.9 | None | SRR1162864 | Other | lineage4.1.2.1 | None | ERR212034 | HR-TB | La1.7;lineage4.9 | None | ERR3797087 | Sensitive | lineage4.9 | None | SRR3675539 | HR-TB | lineage4.9;lineage7 | None | ERR736835 | HR-TB | La1.7;M.canetti;lineage4.9 | None | SRR3675243 | Other | lineage4.9 | None | SRR3675555 | HR-TB | lineage2.1;lineage4.9;lineage7 | None | SRR3675545 | Other | La3;M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | ERR502524 | HR-TB | lineage4.9;lineage6.3 | None | SRR7236177 | Other | La1.8.1 | None | SRR6045952 | HR-TB | M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | ERR4819241 | Other | lineage4.9 | None | ERR1034652 | Other | La3;lineage4.1.2.1;lineage4.2.1;lineage4.5;lineage4.9;lineage6.1.1;lineage6.3.2 | None | ERR176658 | HR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR4188342 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR3468607 | Other | lineage4.9 | None | ERR2693229 | RR-TB | La3;M.canetti;lineage4.9 | None | SRR1172310 | HR-TB | lineage4.9 | None | ERR2026698 | HR-TB | La1.7.1;M.canetti;lineage4.2;lineage4.6.4;lineage4.9;lineage6.2;lineage6.3 | None | SRR6046514 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | SRR3675506 | HR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR5311081 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR3797048 | Other | La3;lineage4.9 | None | ERR323039 | HR-TB | La2;lineage4.9 | None | SRR3675495 | Other | lineage2.1;lineage4.9 | None | ERR702405 | Sensitive | lineage4.9 | None | ERR126608 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | ERR2693231 | Other | La1.6;La3;lineage4.6.4;lineage4.9 | None | SRR6325445 | HR-TB | M.canetti;lineage2.1;lineage4.3.1;lineage4.9;lineage6.3 | None | SRR5341384 | HR-TB | lineage4.9 | None | ERR4769521 | RR-TB | lineage4.9 | None | SRR16156817 | Other | lineage4.9 | None | ERR124636 | Sensitive | lineage4.9 | None | ERR9119138 | RR-TB | M.canetti;lineage4.3.1;lineage4.9 | None | SRR6046644 | HR-TB | La1.6;M.canetti;lineage4.8.1;lineage4.9;lineage6.3 | None | ERR4815441 | HR-TB | lineage4.9 | None | SRR6458421 | MDR-TB | lineage2.2.1 | None | ERR3283032 | Other | lineage4.9 | None | ERR245794 | HR-TB | lineage4.3.4.2.1 | None | ERR4800341 | Other | lineage3 | None | ERR4816478 | HR-TB | lineage4 | None | ERR3797064 | Other | La3;lineage4.9 | None | ERR1035122 | Sensitive | lineage4.9 | None | ERR5311099 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | SRR3675450 | HR-TB | La3;M.canetti;lineage2.1;lineage4.3.1;lineage4.9;lineage6.3 | None | SRR5341308 | Sensitive | lineage4.9 | None | SRR3675456 | RR-TB | lineage4.9;lineage7 | None | SRR5341467 | Other | lineage4.9 | None | ERR3283017 | MDR-TB | M.canetti;lineage2.1;lineage4.1.4;lineage4.3.1;lineage4.9 | None | SRR1183111 | HR-TB | lineage4.9 | None | SRR3675234 | Other | La1.6;La3;lineage4.6.4;lineage4.8.1;lineage4.9 | None | ERR8976043 | HR-TB | lineage2.1;lineage2.2;lineage6.3 | None | SRR1180147 | Other | lineage2.2.1.1 | None | ERR5311090 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR3077978 | RR-TB | lineage1.1 | None | ERR323054 | MDR-TB | La3;M.canetti;lineage3.1 | None | ERR3797014 | Other | La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.8.1;lineage4.9 | None | ERR4814536 | MDR-TB | M.canetti;lineage2.1;lineage3 | None | SRR5341469 | HR-TB | lineage4.9 | None | SRR14066533 | Sensitive | lineage1.1.1 | None | SRR6046196 | Other | La1.7;M.canetti;lineage4.9 | None | SRR6325448 | HR-TB | M.canetti;lineage2.1;lineage4.3.1;lineage4.9;lineage6.3 | None | SRR26159047 | Other | lineage4.6.3;lineage4.9 | None | ERR124652 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | ERR126600 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | SRR6044815 | Other | lineage4.9 | None | ERR323047 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | ERR4819422 | HR-TB | lineage4.9 | None | ERR736875 | HR-TB | lineage4.9 | None | ERR736865 | HR-TB | lineage4.3.2;lineage4.9 | None | ERR2693252 | Sensitive | lineage4.9 | None | SRR6045795 | Sensitive | lineage2.2.1 | None | ERR6866807 | Other | lineage4.9 | None | ERR3797016 | HR-TB | M.canetti;lineage2.1;lineage4.9 | None | SRR7535082 | Sensitive | lineage4.9 | None | ERR038268 | HR-TB | La3;M.canetti;lineage4.8;lineage4.9 | None | ERR9786694 | Other | lineage4.1.2.1 | None | SRR25827418 | XDR-TB | lineage3.1;lineage9 | None | SRR3675222 | Other | La1.7 | None | SRR3675508 | Other | lineage2.1;lineage4.9;lineage6.3 | None | ERR3797029 | Other | lineage4.9 | None | ERR1035239 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR736872 | HR-TB | lineage4.9 | None | ERR323063 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | ERR4810624 | MDR-TB | lineage2.2 | None | ERR736817 | HR-TB | lineage4.3.4 | None | ERR387051 | Other | lineage4.9 | None | ERR3797044 | Other | La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.9 | None | ERR294248 | MDR-TB | lineage2.1;lineage4.9 | None | ERR5311083 | HR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR1063839 | MDR-TB | La2;lineage2.2 | None | ERR323034 | MDR-TB | La3;M.canetti;lineage2.1;lineage3.1 | None | SRR5535933 | Other | lineage4.9 | None | ERR2693245 | HR-TB | La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.8.1;lineage4.9 | None | ERR5162090 | RR-TB | lineage4.9 | None | ERR3797017 | HR-TB | La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.8.1;lineage4.9 | None | SRR3675501 | Other | La1.7;lineage4.9 | None | ERR4188247 | HR-TB | lineage4.9 | None | SRR9970980 | HR-TB | lineage4.1.2 | None | ERR473277 | HR-TB | La3;M.canetti;lineage4.9 | None | ERR5311100 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | SRR6046577 | Other | lineage4.6.3;lineage4.9 | None | ERR4820773 | HR-TB | lineage4.9 | None | ERR323036 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | ERR2693228 | RR-TB | lineage4.9 | None | ERR3797061 | Other | La1.6;La3;lineage4.9 | None | SRR17658565 | Pre-XDR-TB | lineage3 | None | ERR323040 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | SRR14801759 | HR-TB | La1.7;lineage4.9 | None | ERR4798099 | Other | lineage4.9 | None | SRR3675235 | Sensitive | lineage4.9 | None | SRR16058049 | Sensitive | lineage4.3.3 | None | SRR3675267 | Other | La1.7;lineage4.9 | None | SRR3675486 | HR-TB | M.canetti;lineage2.1;lineage4.3.1;lineage4.9;lineage6.3 | None | ERR736856 | Sensitive | lineage4.9 | None | ERR502510 | Sensitive | lineage4.9 | None | SRR6045347 | Other | lineage4.9 | None | ERR5311078 | MDR-TB | M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | ERR4798648 | MDR-TB | lineage3.1.2.2 | None | ERR4798504 | RR-TB | lineage3 | None | ERR3283016 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | ERR3283047 | Sensitive | La3;lineage4.9 | None | SRR5341461 | HR-TB | lineage4.9 | None | ERR3283020 | HR-TB | La1.6;La3;M.canetti;lineage2.1;lineage4.9 | None | SRR29231479 | RR-TB | lineage4.9 | None | SRR6325447 | MDR-TB | lineage2.1;lineage4.1.1.1;lineage6.3 | None | SRR3675280 | RR-TB | lineage4.9 | None | SRR5341323 | Sensitive | lineage4.9 | None | ERR3273109 | HR-TB | lineage4 | None | ERR278594 | HR-TB | lineage2.1;lineage4.9 | None | ERR2693230 | HR-TB | La1.6;La3;M.canetti;lineage2.1;lineage4.6.4;lineage4.8.1;lineage4.9 | None | SRR29096659 | Sensitive | lineage4.9 | None | ERR3804169 | HR-TB | lineage4.1.3 | None | SRR6045290 | RR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR126618 | MDR-TB | La3;M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | SRR14802079 | MDR-TB | lineage4.2.1 | None | SRR5341453 | Other | lineage4.9 | None | ERR4188350 | HR-TB | M.canetti;lineage2.1;lineage4.9 | None | SRR3675518 | MDR-TB | M.canetti;lineage2.1;lineage4.3.1;lineage4.9;lineage6.3 | None | ERR9786611 | HR-TB | lineage4.1.3 | None | SRR3675449 | Other | M.canetti;lineage4.9 | None | SRR3675246 | Other | lineage4.9 | None | ERR323055 | MDR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | SRR6045519 | MDR-TB | M.canetti;lineage4.9 | None | SRR3675488 | Other | La1.7;lineage4.9 | None | ERR5311096 | HR-TB | M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | ERR5311102 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR6358991 | HR-TB | lineage4.8.1;lineage4.9;lineage6.1.3;lineage6.3 | None | ERR13266453 | HR-TB | lineage3 | None | ERR9125338 | Sensitive | lineage4.3.3 | None | SRR5341299 | HR-TB | lineage4.9 | None | ERR323041 | HR-TB | M.canetti;lineage2.1 | None | ERR386953 | HR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR3283025 | MDR-TB | La1.7;lineage4.9 | None | SRR3675554 | HR-TB | M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | SRR5341387 | Other | lineage4.9 | None | ERR181824 | HR-TB | lineage4.9 | None | ERR3797079 | Sensitive | lineage4.9 | None | SRR1180226 | HR-TB | lineage4.9 | None | ERR4797474 | Sensitive | lineage4.9 | None | SRR7240492 | HR-TB | La1.7.1 | None | SRR3675558 | HR-TB | M.canetti;lineage4.1.1.3;lineage6.3;lineage8 | None | SRR6046382 | Sensitive | lineage2.2.1 | None | SRR1640750 | Other | None | SRR3675568 | HR-TB | M.canetti;lineage2.1;lineage4.9;lineage6.3;lineage8 | None | ERR323060 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | ERR5311098 | HR-TB | M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | ERR6358837 | HR-TB | La3;M.canetti;lineage2.1;lineage4.3.1;lineage4.9;lineage6.3 | None | SRR3675505 | Other | La1.7;M.canetti;lineage4.9 | None | ERR1063858 | HR-TB | lineage4.9 | None | ERR323044 | HR-TB | lineage4.3.4.2.1 | None | ERR3797023 | HR-TB | La1.8.1 | None | SRR1158918 | Sensitive | lineage4.9 | None | SRR3675322 | HR-TB | M.canetti;lineage2.1;lineage4.1.4;lineage4.9 | None | ERR4818929 | HR-TB | lineage4.9 | None | ERR137286 | Other | lineage4.9 | None | SRR3675385 | Other | La1.7;lineage4.9 | None | ERR3283024 | Other | La1.6;La3;M.canetti;lineage4.6.4;lineage4.9 | None | ERR2693257 | Other | La1.6;La3;M.canetti;lineage4.8.1;lineage4.9 | None | ERR323058 | HR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | ERR2693242 | RR-TB | lineage2.1;lineage4.9 | None | ERR3283028 | Other | La3;lineage4 | None | ERR1063896 | Sensitive | None | ERR502511 | Sensitive | lineage4.9 | None | SRR1159378 | Other | lineage4.9 | None | ERR2026695 | MDR-TB | La1.7.1;M.canetti;lineage4.2;lineage6.2;lineage6.3 | None | ERR124651 | MDR-TB | La3;M.canetti;lineage2.1;lineage4.1.4;lineage4.9;lineage6.3 | None | ERR4821053 | RR-TB | lineage3 | None | ERR5311101 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | SRR3675492 | Other | La1.7;lineage4.9 | None | ERR124642 | MDR-TB | M.canetti;lineage2.1;lineage4.1.4;lineage4.9;lineage6.3 | None | ERR2026697 | HR-TB | La1.7.1;M.canetti;lineage4.2;lineage4.6.4;lineage4.9;lineage6.2;lineage6.3 | None | SRR3675231 | MDR-TB | lineage4.9;lineage7 | None | SRR5341341 | Pre-XDR-TB | lineage2.2.1 | None | ERR926162 | Sensitive | lineage4.9 | None | ERR736848 | Other | lineage4.9 | None | SRR5341300 | HR-TB | lineage4.9 | None | ERR4799025 | Other | lineage4.8 | None | ERR1063857 | MDR-TB | La2;lineage4.9 | None | ERR4816551 | HR-TB | lineage4.1.1.3 | None | SRR1174897 | MDR-TB | lineage4.9;lineage9 | None | ERR3283031 | Sensitive | La3;lineage4.9 | None | ERR3283014 | Sensitive | La3;lineage4.9 | None | SRR13423649 | Sensitive | lineage2.2.1 | None | SRR5341366 | Sensitive | lineage4.9 | None | SRR29096879 | Sensitive | lineage4.9 | None | SRR3675461 | RR-TB | lineage4.9 | None | ERR323064 | MDR-TB | La3;M.canetti;lineage2.1;lineage4.9 | None | ERR3797063 | Sensitive | La3;lineage4.9 | None | ERR4797184 | Sensitive | lineage4.9 | None | SRR5341470 | MDR-TB | lineage4.9;lineage9 | None | ERR3283011 | Other | La3;lineage4.9 | None | SRR9970981 | RR-TB | lineage4.3.2.1 | None | SRR3675481 | MDR-TB | M.canetti;lineage2.1;lineage4.9;lineage6.3 | None | ERR1063862 | HR-TB | lineage4.9 | None | SRR3675561 | Other | M.canetti;lineage2.1;lineage4.9 | None | ERR1023525 | HR-TB | La1.7;lineage4.9 | None | ERR1023295 | MDR-TB | M.canetti;lineage2.1;lineage4.1.2.1 | None | SRR3675515 | HR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR323053 | MDR-TB | La2;lineage4.9;lineage9 | None | ERR1063859 | HR-TB | La1.7.1;lineage4.9 | None | ERR5311089 | HR-TB | M.canetti;lineage2.1;lineage4.9 | None | SRR5341303 | Sensitive | lineage4.9 | None | ERR4819877 | HR-TB | lineage4.9 | None | SRR6045948 | MDR-TB | M.canetti;lineage2.1;lineage4.9 | None | ERR4817731 | HR-TB | lineage4.9 | None | SRR6325444 | MDR-TB | M.canetti;lineage2.1;lineage6.3 | None | SRR8217918 | HR-TB | lineage4.9 | None | SRR12416842 | HR-TB | lineage4.9 | None | ERR133825 | HR-TB | La1;lineage4.9 | None | ERR1063849 | HR-TB | lineage4.9 | None | ERR4816656 | Other | lineage4.9 | None | ERR176766 | HR-TB | lineage2.1;lineage4.9 | None | ERR2026696 | MDR-TB | La1.7.1;M.canetti;lineage4.2;lineage4.9;lineage6.2;lineage6.3 | None | SRR3675441 | Other | lineage4.9 | None | ERR323056 | HR-TB | lineage4.4.1.2 | None |
|---|
