TB-Profiler result

Run: SRR14801759

Summary

Run ID: SRR14801759

Sample name:

Date: 2024-04-14T05:57:12.590237

Number of reads: 569842

Percentage reads mapped: 14.94

Median coverage: 1.0

Strain: La1.7;lineage4.9

Spoligotype:

Drug-resistance: MDR-TB


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Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
La1.7 M.bovis None 0.13
lineage4 Euro-American None 1.0
lineage4.9 Euro-American (H37Rv-like) None 0.97
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin rpoB c.1327_1329delTTGinsCC Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
isoniazid kasA p.Arg121Lys Mutation from literature
ethambutol embB p.Asp311Gly Mutation from literature
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid fgd1 c.196_198delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.202_204delCTGinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.301_303delGTTinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
c.730_732delAACinsGG Assoc w R - Interim Confers DLM-PMD cross-resistance
c.817_819delGATinsAC Assoc w R - Interim Confers DLM-PMD cross-resistance
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
fgd1 490978 c.196_198delAACinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 490984 c.202_204delCTGinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491083 c.301_303delGTTinsAC frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491512 c.730_732delAACinsGG frameshift_variant&missense_variant 1.0 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
fgd1 491599 c.817_819delGATinsAC frameshift_variant&missense_variant 0.96 pretomanid Assoc w R - Interim Confers DLM-PMD cross-resistance
delamanid Assoc w R - Interim Confers DLM-PMD cross-resistance
rpoB 761133 c.1327_1329delTTGinsCC frameshift_variant&missense_variant 0.98 rifampicin Assoc w R - Interim Expert rule: Non-silent variants in RRDR of rpoB
kasA 2518476 p.Arg121Lys missense_variant 1.0 isoniazid Mutation from literature
embB 4247445 p.Asp311Gly missense_variant 1.0 ethambutol Mutation from literature
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrB 6148 c.909C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrB 6170 p.His311Ala missense_variant 0.96 levofloxacin
moxifloxacin
gyrB 6178 c.939C>T synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrB 6203 p.Ser322Ala missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6214 c.975G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6215 c.976_978delTCGinsAC frameshift_variant&missense_variant 0.98 levofloxacin Uncertain significance
moxifloxacin
gyrB 6223 c.984G>C synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6238 c.999G>A synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6242 p.Arg335Lys missense_variant 0.98 levofloxacin
moxifloxacin
gyrB 6250 c.1011A>G synonymous_variant 0.98 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6253 c.1014G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6256 c.1017G>A synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6280 c.1041T>C synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrB 6286 c.1047T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6292 c.1053G>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrB 6298 c.1059C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 6307 c.-995T>C upstream_gene_variant 0.95 levofloxacin
moxifloxacin
gyrA 6310 c.-992G>C upstream_gene_variant 0.97 levofloxacin
moxifloxacin
gyrB 6319 c.1080G>C synonymous_variant 0.97 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrB 6326 p.Ser363Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrB 6346 c.1107C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6649 c.-653T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6655 c.-647T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6673 c.-629A>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6676 c.-626T>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6680 c.1441C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6700 c.-602T>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6703 c.-599G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6709 c.-593A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6712 c.-590G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6730 c.-572A>G upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6739 c.-563C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6745 c.1506T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 6751 c.-551G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6760 c.-542G>C upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6775 c.-527G>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrA 6778 c.-524C>T upstream_gene_variant 1.0 levofloxacin
moxifloxacin
gyrB 6793 c.1554T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrB 6797 p.Gly520Thr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7391 c.90C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7394 c.93T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7412 c.111C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7424 c.123G>A synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7427 c.126G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7433 c.132G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7442 c.141G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7451 c.150C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7457 c.156T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7472 c.171T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin
gyrA 7475 c.174A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7480 p.Phe60Tyr missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 7484 c.183T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7487 c.186C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7490 c.189C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7496 c.195C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7499 c.198G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7514 c.213C>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7517 c.216G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7520 c.219G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7523 c.222C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7526 c.225G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7529 c.228G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7541 c.240C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7585 p.Ser95Thr missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
gyrA 7592 c.291G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7595 c.294C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7607 c.306C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7619 c.318C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7631 c.330G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7637 c.336C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7658 c.357A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7661 c.360C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7664 c.363T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7667 c.366C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7670 c.369A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7676 c.375G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 7710 c.409T>C synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 7728 c.427_429delAGGinsCC frameshift_variant&missense_variant 0.98 levofloxacin
moxifloxacin
gyrA 7745 p.Glu148Asp missense_variant 0.96 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 7751 c.450C>T synonymous_variant 0.96 levofloxacin
moxifloxacin
gyrA 7763 c.462T>G synonymous_variant 0.95 levofloxacin
moxifloxacin
gyrA 7775 c.474C>T synonymous_variant 0.93 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7778 c.477G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7784 c.483A>G synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7787 c.486G>A synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7790 c.489G>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7797 c.496_498delCTAinsTG frameshift_variant&stop_gained 0.92 levofloxacin
moxifloxacin
gyrA 7802 c.501C>G synonymous_variant 0.92 levofloxacin
moxifloxacin
gyrA 7814 c.513C>G synonymous_variant 0.92 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7832 c.531G>T synonymous_variant 0.91 levofloxacin
moxifloxacin
gyrA 7835 c.534A>G synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7841 c.540C>T synonymous_variant 0.91 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 7859 c.558A>C synonymous_variant 0.94 levofloxacin
moxifloxacin
gyrA 7865 c.564T>C synonymous_variant 0.93 levofloxacin
moxifloxacin
gyrA 7874 c.573G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8129 c.828T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8156 c.855T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8177 c.876A>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8198 c.897T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8199 p.Ser300Ala missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8207 c.906T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8219 c.918T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8225 c.924T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8231 c.930C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8235 c.934_936delTTAinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8253 p.Ile318Leu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8258 c.957G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8261 c.960C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8264 c.963T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8267 c.966G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8283 c.982_984delATCinsCG frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8288 c.987T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8294 c.993T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8315 c.1014G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8324 c.1023T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8339 c.1038A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8340 p.Ala347Ser missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8357 c.1056G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8382 p.Leu361Met missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8390 c.1089C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8391 c.1090_1092delTATinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8399 c.1098T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8405 c.1104C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8414 c.1113C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8420 c.1119T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8421 c.1120_1122delGTGinsAC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8447 c.1146C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8453 c.1152A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8459 c.1158G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8462 c.1161A>G synonymous_variant 0.98 levofloxacin
moxifloxacin
gyrA 8468 c.1167C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8480 c.1179C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8486 c.1185T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8489 c.1188A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8501 c.1200G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8504 c.1203G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8513 c.1212C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8516 c.1215T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8519 c.1218A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8520 c.1219C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8546 c.1245T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8556 p.Ala419Gln missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8561 c.1260A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8588 p.Glu429Asp missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8603 c.1302A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8619 c.1318T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8624 c.1323G>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8627 c.1326C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8636 c.1335A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8645 c.1344C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8655 p.Ile452Val missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8666 c.1365G>C synonymous_variant 0.97 levofloxacin
moxifloxacin
gyrA 8672 c.1371A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8693 c.1392T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8711 c.1410A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8714 c.1413A>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8729 c.1428T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8732 c.1431G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8767 p.Arg489Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8783 c.1482G>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8813 p.Asp504Glu missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 8828 c.1527T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8829 c.1528T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8837 c.1536C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8852 c.1551T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8858 c.1557T>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8867 c.1566A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8870 c.1569G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8873 c.1572A>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8897 c.1596T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8903 c.1602T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8924 c.1623C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8939 c.1638T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8942 c.1641G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8946 c.1645_1647delTTGinsCC frameshift_variant&missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8951 c.1650G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8967 p.Ala556Asn missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 8981 c.1680G>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 8987 c.1686C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8990 c.1689C>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8996 c.1695T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 8998 p.Leu566Trp missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9182 c.1881T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9185 c.1884C>T synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9188 p.Asn629Lys missense_variant 1.0 levofloxacin Uncertain significance
moxifloxacin Uncertain significance
gyrA 9191 c.1890G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9200 c.1899A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9206 c.1905C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9207 p.Lys636Arg missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9227 c.1926C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9230 c.1929T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9236 c.1935G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9242 c.1941A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9263 c.1962C>T synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9267 p.Asn656Gly missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9275 c.1974G>A synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9287 c.1986G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9296 c.1995T>C synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9304 p.Gly668Glu missense_variant 1.0 levofloxacin
moxifloxacin
gyrA 9323 c.2022C>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9335 c.2034G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9341 c.2040C>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9345 c.2044A>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9374 c.2073G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9377 c.2076A>G synonymous_variant 1.0 levofloxacin Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
gyrA 9383 c.2082T>C synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9386 c.2085T>G synonymous_variant 1.0 levofloxacin
moxifloxacin
gyrA 9413 c.2112G>C synonymous_variant 1.0 levofloxacin
moxifloxacin
fgd1 490809 c.27A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490818 c.36C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490824 c.42A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490830 c.48A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490839 c.57G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490851 c.69A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490853 p.Ala24Gly missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490857 c.75C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490859 p.Ala26Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490869 c.87C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490899 c.117C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490902 c.120T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490905 c.123T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490911 c.129T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490920 c.138C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 490921 p.Gln47Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490935 c.153C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490947 c.165G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490948 p.Ser56Ala missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490959 c.177C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490962 c.180T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490968 c.186C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490974 c.192T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490987 p.Leu69Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 490998 c.216T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491010 c.228C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491013 c.231C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491016 c.234C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491037 c.255C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491043 c.261T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491049 c.267T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491064 c.282A>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491067 c.285C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fgd1 491070 c.288G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491073 c.291C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491082 c.300T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491091 c.309T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491094 c.312C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491106 c.324T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491115 c.333G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491121 c.339A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491133 c.351A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491142 c.360C>T synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fgd1 491144 p.Ala121Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491181 c.399T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491187 c.405G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491191 p.Gly137Arg missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491196 c.414A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491202 c.420G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491203 p.Gln141Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491212 p.Ser144Val missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491223 c.441C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491226 c.444C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491229 c.447C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491232 c.450T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491241 p.Asp153Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491244 c.462T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491262 c.480C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491484 c.702C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491487 c.705C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491502 p.Glu240Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491508 c.726A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491509 c.727T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491526 c.744T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491542 c.760T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491547 c.765A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491550 c.768T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fgd1 491610 c.828A>C synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fgd1 491620 p.Ile280Val missense_variant 0.94 clofazimine
pretomanid
delamanid
fgd1 491640 c.858G>C synonymous_variant 0.9 clofazimine
pretomanid
delamanid
fgd1 491646 c.864G>A synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491649 c.867C>T synonymous_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491658 p.Glu292Asp missense_variant 0.82 clofazimine
pretomanid
delamanid
fgd1 491664 c.882C>G synonymous_variant 0.8 clofazimine
pretomanid
delamanid
mshA 575561 p.Met72Val missense_variant 0.93 ethionamide
isoniazid
mshA 575571 p.Ser75Thr missense_variant 0.93 ethionamide
isoniazid
mshA 575581 p.His78Gln missense_variant 0.94 ethionamide
isoniazid
mshA 575582 p.Leu79Met missense_variant 0.94 ethionamide
isoniazid
mshA 575590 c.243T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575593 c.246G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575597 p.Ile84Val missense_variant 0.94 ethionamide
isoniazid
mshA 575618 c.271C>A synonymous_variant 0.94 ethionamide
isoniazid
mshA 575623 c.276C>A synonymous_variant 0.94 ethionamide
isoniazid
mshA 575627 c.280_282delGCAinsTG frameshift_variant&stop_gained 0.94 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575635 c.288A>C synonymous_variant 0.94 ethionamide
isoniazid Not assoc w R - Interim
mshA 575638 c.291T>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575639 c.292_294delCCAinsGG frameshift_variant&missense_variant 0.94 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575644 c.297G>C synonymous_variant 0.94 ethionamide
isoniazid
mshA 575652 p.Arg102Pro missense_variant 0.94 ethionamide
isoniazid
mshA 575659 c.312A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575662 c.315C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575671 c.324G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575689 c.342G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575695 c.348C>G synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
mshA 575704 c.357T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575705 c.358_360delTTGinsCC frameshift_variant&missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575725 c.378C>T synonymous_variant 0.96 ethionamide
isoniazid
mshA 575734 c.387T>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575737 c.390T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575744 p.Ala133Thr missense_variant 1.0 ethionamide
isoniazid Uncertain significance
mshA 575749 c.402C>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575752 c.405G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575771 p.Val142Thr missense_variant 1.0 ethionamide
isoniazid
mshA 575776 c.429C>T synonymous_variant 1.0 ethionamide
isoniazid
mshA 575779 c.432A>G synonymous_variant 1.0 ethionamide
isoniazid
mshA 575782 c.435G>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575785 c.438T>C synonymous_variant 1.0 ethionamide
isoniazid
mshA 575830 c.483C>G synonymous_variant 0.94 ethionamide
isoniazid
mshA 575842 c.495G>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575843 c.496_498delCGCinsAG frameshift_variant&missense_variant 0.9 ethionamide Uncertain significance
isoniazid Uncertain significance
mshA 575851 c.504C>G synonymous_variant 0.91 ethionamide
isoniazid
mshA 575864 c.517T>C synonymous_variant 0.9 ethionamide
isoniazid
mshA 575878 c.531A>G synonymous_variant 0.82 ethionamide
isoniazid
mshA 575896 c.549G>C synonymous_variant 0.73 ethionamide
isoniazid
mshA 575905 c.558G>C synonymous_variant 0.73 ethionamide
isoniazid
mshA 575908 c.561A>G synonymous_variant 0.73 ethionamide
isoniazid
mshA 575920 c.573C>T synonymous_variant 0.73 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
mshA 575925 p.Gly193Ala missense_variant 0.73 ethionamide
isoniazid
mshA 575932 c.585G>A synonymous_variant 0.73 ethionamide
isoniazid
ccsA 620238 c.348G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620245 c.355T>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620256 c.366C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620264 p.Gly125Ala missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620271 c.381C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620284 p.Ala132Pro missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620288 p.Arg133Gln missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620295 c.405G>C synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620296 p.Pro136Ala missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620307 c.417C>G synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620311 p.Leu141Val missense_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620316 c.426G>C synonymous_variant 0.96 capreomycin
amikacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
ccsA 620319 c.429C>T synonymous_variant 0.96 capreomycin
amikacin
kanamycin
ccsA 620337 c.447C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620340 c.450C>G synonymous_variant 0.95 capreomycin
amikacin
kanamycin
ccsA 620346 c.456C>G synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620349 c.459A>C synonymous_variant 0.94 capreomycin
amikacin
kanamycin
ccsA 620362 p.Ala158Thr missense_variant 0.93 capreomycin
amikacin
kanamycin
ccsA 620604 c.714C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620607 c.717T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620625 c.735A>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620631 c.741T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620634 c.744C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620649 c.759A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620652 c.762C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620676 c.786C>T synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620688 c.798G>A synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620694 c.804C>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620698 p.Val270Ile missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620703 c.813G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620709 c.819G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620710 c.820_822delGTGinsAC frameshift_variant&missense_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620721 c.831G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620733 c.843G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620736 c.846G>C synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620739 c.849A>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
ccsA 620748 c.858T>G synonymous_variant 1.0 capreomycin
amikacin
kanamycin
Rv0565c 655938 c.-127_*71del transcript_ablation 0.9 ethionamide Uncertain significance
Rv0565c 657670 c.-200A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657671 c.-201A>G upstream_gene_variant 1.0 ethionamide
Rv0565c 657678 c.-209_-208delAAinsGG upstream_gene_variant 1.0 ethionamide
Rv0565c 657686 c.-216C>T upstream_gene_variant 1.0 ethionamide
Rv0565c 657689 c.-220_-219delCAinsAG upstream_gene_variant 1.0 ethionamide
Rv0565c 657716 c.-246G>A upstream_gene_variant 1.0 ethionamide
Rv0565c 657732 c.-262G>C upstream_gene_variant 1.0 ethionamide
Rv0565c 657734 c.-264T>C upstream_gene_variant 1.0 ethionamide
nusG 734407 c.154_156delGTTinsAC frameshift_variant&missense_variant 1.0 rifampicin
nusG 734413 c.160_161delTCinsAG synonymous_variant 1.0 rifampicin
nusG 734421 c.168A>C synonymous_variant 1.0 rifampicin
nusG 734424 c.171G>C synonymous_variant 1.0 rifampicin
nusG 734439 c.186C>G synonymous_variant 0.95 rifampicin
nusG 734451 c.198G>C synonymous_variant 0.93 rifampicin
nusG 734454 c.201A>G synonymous_variant 0.93 rifampicin
nusG 734460 c.207G>C synonymous_variant 0.93 rifampicin
nusG 734472 c.219T>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734475 c.222T>C synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734499 c.246G>C synonymous_variant 0.91 rifampicin
nusG 734532 c.279A>G synonymous_variant 0.9 rifampicin Not assoc w R - Interim
nusG 734541 c.288A>G synonymous_variant 0.88 rifampicin Not assoc w R - Interim
nusG 734559 c.306T>C synonymous_variant 0.88 rifampicin
nusG 734566 c.313_315delCTGinsTA frameshift_variant&stop_gained 0.86 rifampicin
nusG 734571 c.318C>G synonymous_variant 0.86 rifampicin
nusG 734574 c.321C>T synonymous_variant 0.86 rifampicin
nusG 734580 c.327T>C synonymous_variant 0.86 rifampicin Not assoc w R - Interim
nusG 734595 p.Asp114Glu missense_variant 0.82 rifampicin
nusG 734596 c.343_345delTTGinsCC frameshift_variant&missense_variant 0.82 rifampicin
nusG 734600 p.Thr116Asn missense_variant 0.9 rifampicin Uncertain significance
nusG 734607 p.Asp118Glu missense_variant 0.9 rifampicin
nusG 734610 c.357C>G synonymous_variant 0.9 rifampicin
nusG 734615 p.Ala121Gly missense_variant 0.9 rifampicin
rpoB 760181 c.375T>G synonymous_variant 1.0 rifampicin
rpoB 760184 c.378A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760196 c.390C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760208 p.Ile134Met missense_variant 1.0 rifampicin
rpoB 760212 p.Asn136Ala missense_variant 1.0 rifampicin
rpoB 760215 c.409_411delAACinsGG frameshift_variant&missense_variant 1.0 rifampicin
rpoB 760219 p.Thr138Ser missense_variant 1.0 rifampicin
rpoB 760223 c.417T>C synonymous_variant 1.0 rifampicin
rpoB 760235 c.429T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760283 c.477G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760298 c.492G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760304 c.498G>A synonymous_variant 1.0 rifampicin
rpoB 760310 c.504G>C synonymous_variant 1.0 rifampicin
rpoB 760316 c.510C>G synonymous_variant 1.0 rifampicin
rpoB 760317 c.511_512delAGinsTC synonymous_variant 1.0 rifampicin
rpoB 760328 c.522G>C synonymous_variant 1.0 rifampicin
rpoB 760331 c.525G>T synonymous_variant 1.0 rifampicin
rpoB 760340 c.534G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760358 c.552C>G synonymous_variant 1.0 rifampicin
rpoB 760361 c.555T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760376 p.Asp190Glu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760406 c.600G>C synonymous_variant 1.0 rifampicin
rpoB 760407 p.Ser201Gly missense_variant 1.0 rifampicin Uncertain significance
rpoB 760415 c.609C>G synonymous_variant 1.0 rifampicin
rpoB 760424 c.618C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760430 c.624T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760457 c.651C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760478 c.672C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760481 c.675G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760484 c.678A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760487 c.681G>C synonymous_variant 1.0 rifampicin
rpoB 760522 p.Ser239Asn missense_variant 1.0 rifampicin Uncertain significance
rpoB 760532 c.726T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760533 p.Val243Thr missense_variant 1.0 rifampicin
rpoB 760547 c.741G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760551 c.745_746delTCinsAG synonymous_variant 1.0 rifampicin
rpoB 760563 c.757delCinsAT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoB 760566 p.Ser254Ala missense_variant 1.0 rifampicin
rpoB 760567 c.762delG frameshift_variant 1.0 rifampicin
rpoB 760591 p.Val262Ala missense_variant 1.0 rifampicin
rpoB 760611 c.805T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760646 c.840C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760655 c.849A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760661 c.855A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 760670 c.864G>C synonymous_variant 1.0 rifampicin
rpoB 760674 c.868T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760679 c.873A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760683 c.877T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760718 c.912C>G synonymous_variant 1.0 rifampicin
rpoB 760721 c.915C>G synonymous_variant 1.0 rifampicin
rpoB 760730 c.924T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760916 c.1110C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760925 c.1119T>C synonymous_variant 1.0 rifampicin
rpoB 760946 c.1140A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760952 c.1146G>A synonymous_variant 1.0 rifampicin
rpoB 760961 c.1155C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760965 p.Met387Leu missense_variant 1.0 rifampicin Uncertain significance
rpoB 760970 c.1164G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760973 c.1167G>C synonymous_variant 1.0 rifampicin
rpoB 760982 c.1176G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760985 c.1179G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760988 c.1182C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 760991 c.1185G>C synonymous_variant 1.0 rifampicin
rpoB 761003 c.1197C>G synonymous_variant 1.0 rifampicin
rpoB 761015 c.1209G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761027 c.1221A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761036 c.1230G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761037 c.1231T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761051 c.1245G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761054 c.1248G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761057 c.1251G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761060 c.1254C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761096 c.1290G>C synonymous_variant 0.94 rifampicin
rpoB 761097 c.1291_1292delAGinsTC synonymous_variant 0.94 rifampicin
rpoB 761102 c.1296A>G synonymous_variant 0.97 rifampicin
rpoB 761150 c.1344A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761153 c.1347G>T synonymous_variant 0.98 rifampicin
rpoB 761165 c.1359G>C synonymous_variant 0.89 rifampicin Not assoc w R - Interim
rpoB 761180 c.1374A>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761189 c.1383T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761195 c.1389G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761198 c.1392G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761204 c.1398C>G synonymous_variant 0.98 rifampicin
rpoB 761219 c.1413G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761220 c.1414_1416delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoB 761249 c.1443A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761255 c.1449T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761258 c.1452G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761261 c.1455G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761273 c.1467T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761282 c.1476C>G synonymous_variant 1.0 rifampicin
rpoB 761318 c.1512G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761327 c.1521A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761346 p.Val514Arg missense_variant 1.0 rifampicin
rpoB 761355 c.1549_1551delGTGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoB 761360 c.1554T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761362 p.Ser519Thr missense_variant 1.0 rifampicin
rpoB 761374 p.Val523Glu missense_variant 1.0 rifampicin
rpoB 761408 c.1602G>C synonymous_variant 0.95 rifampicin
rpoB 761414 c.1608A>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 761423 c.1617T>C synonymous_variant 0.9 rifampicin
rpoB 761537 c.1731C>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoB 761555 c.1749G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761558 c.1752C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761561 c.1755C>A synonymous_variant 1.0 rifampicin
rpoB 761570 c.1764T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761573 c.1767C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761579 c.1773G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761600 c.1794T>C synonymous_variant 1.0 rifampicin
rpoB 761606 c.1800C>G synonymous_variant 1.0 rifampicin
rpoB 761612 c.1806G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761615 c.1809A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761636 c.1830G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761645 c.1839C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761648 c.1842T>C synonymous_variant 1.0 rifampicin
rpoB 761666 c.1860G>C synonymous_variant 1.0 rifampicin
rpoB 761669 c.1863C>T synonymous_variant 1.0 rifampicin
rpoB 761675 c.1869G>C synonymous_variant 1.0 rifampicin
rpoB 761682 c.1876C>T synonymous_variant 1.0 rifampicin
rpoB 761687 c.1881C>T synonymous_variant 1.0 rifampicin
rpoB 761690 c.1884G>C synonymous_variant 1.0 rifampicin
rpoB 761735 c.1929C>G synonymous_variant 1.0 rifampicin
rpoB 761747 c.1941G>C synonymous_variant 1.0 rifampicin
rpoB 761750 c.1944G>C synonymous_variant 1.0 rifampicin
rpoB 761765 c.1959T>C synonymous_variant 0.98 rifampicin
rpoB 761772 p.His656Ala missense_variant 0.97 rifampicin
rpoB 761778 p.Asn658Asp missense_variant 0.97 rifampicin
rpoB 761791 p.Arg662His missense_variant 0.98 rifampicin
rpoB 761813 c.2007T>C synonymous_variant 0.98 rifampicin
rpoB 761819 c.2013G>C synonymous_variant 0.98 rifampicin
rpoB 761834 c.2028T>C synonymous_variant 0.98 rifampicin
rpoB 761847 p.Cys681Arg missense_variant 0.98 rifampicin Uncertain significance
rpoB 761852 c.2046C>G synonymous_variant 0.98 rifampicin
rpoB 761858 c.2052G>C synonymous_variant 0.98 rifampicin
rpoB 761864 c.2058G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 761873 c.2067A>G synonymous_variant 0.98 rifampicin
rpoB 761876 c.2070C>G synonymous_variant 0.99 rifampicin
rpoB 761885 c.2079T>C synonymous_variant 0.99 rifampicin
rpoB 761897 c.2091C>G synonymous_variant 0.98 rifampicin
rpoB 761903 c.2097T>G synonymous_variant 0.98 rifampicin
rpoB 761906 c.2100C>G synonymous_variant 0.98 rifampicin
rpoB 761909 c.2103T>C synonymous_variant 1.0 rifampicin
rpoB 761912 c.2106T>C synonymous_variant 1.0 rifampicin
rpoB 761915 p.Asp703Glu missense_variant 1.0 rifampicin
rpoB 761916 p.Asp704Asn missense_variant 1.0 rifampicin
rpoB 761921 c.2115C>T synonymous_variant 1.0 rifampicin
rpoB 761948 c.2142G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 761951 c.2145G>C synonymous_variant 1.0 rifampicin
rpoB 761955 p.Ile717Val missense_variant 1.0 rifampicin Uncertain significance
rpoB 761999 c.2193G>C synonymous_variant 1.0 rifampicin
rpoB 762029 c.2223C>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762053 c.2247T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762062 c.2256T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762065 c.2259T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762083 c.2277T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762086 c.2280G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762101 c.2295C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 762114 p.Ile770Val missense_variant 0.99 rifampicin Uncertain significance
rpoB 762122 c.2316C>T synonymous_variant 0.99 rifampicin
rpoB 762131 c.2325C>G synonymous_variant 0.98 rifampicin
rpoB 762140 c.2334G>C synonymous_variant 0.98 rifampicin
rpoB 762143 c.2337T>C synonymous_variant 0.98 rifampicin
rpoB 762149 c.2343G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762158 c.2352G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762167 c.2361T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762176 c.2370T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762185 c.2379G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762218 c.2412T>C synonymous_variant 1.0 rifampicin
rpoB 762233 c.2427G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762246 c.2440C>T synonymous_variant 1.0 rifampicin
rpoB 762251 c.2445G>C synonymous_variant 1.0 rifampicin
rpoB 762254 c.2448T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762257 c.2451C>G synonymous_variant 1.0 rifampicin
rpoB 762275 c.2469C>G synonymous_variant 1.0 rifampicin
rpoB 762284 c.2478G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762293 c.2487T>G synonymous_variant 1.0 rifampicin
rpoB 762308 c.2502G>C synonymous_variant 1.0 rifampicin
rpoB 762314 c.2508C>T synonymous_variant 1.0 rifampicin
rpoB 762317 c.2511A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762338 c.2532T>C synonymous_variant 1.0 rifampicin
rpoB 762341 c.2535G>C synonymous_variant 1.0 rifampicin
rpoB 762347 c.2541T>C synonymous_variant 0.98 rifampicin
rpoB 762362 p.Glu852Asp missense_variant 1.0 rifampicin
rpoC 762390 c.-980C>T upstream_gene_variant 1.0 rifampicin
rpoC 762395 c.-975G>C upstream_gene_variant 1.0 rifampicin
rpoC 762398 c.-972T>C upstream_gene_variant 1.0 rifampicin
rpoC 762401 c.-969G>C upstream_gene_variant 1.0 rifampicin
rpoB 762404 c.2598T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762407 c.-963G>C upstream_gene_variant 1.0 rifampicin
rpoB 762410 c.2604T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762416 c.2610A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762449 c.2643C>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762452 c.2646G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762470 c.2664G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762488 c.2682G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 762491 c.2685T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 762509 c.-861T>G upstream_gene_variant 0.98 rifampicin
rpoB 762510 c.2704_2706delGCCinsCT frameshift_variant&missense_variant 0.98 rifampicin
rpoC 762521 c.-849C>T upstream_gene_variant 0.97 rifampicin
rpoC 762527 c.-843G>C upstream_gene_variant 0.97 rifampicin
rpoC 762533 c.-837T>C upstream_gene_variant 0.97 rifampicin
rpoC 762536 c.-834T>C upstream_gene_variant 0.97 rifampicin
rpoC 762537 c.-833T>C upstream_gene_variant 0.97 rifampicin
rpoC 762551 c.-819C>T upstream_gene_variant 0.97 rifampicin
rpoC 762581 c.-789T>C upstream_gene_variant 0.92 rifampicin
rpoC 762582 c.-788T>C upstream_gene_variant 0.92 rifampicin
rpoC 762590 c.-780C>G upstream_gene_variant 0.94 rifampicin
rpoC 762596 c.-774G>C upstream_gene_variant 0.88 rifampicin
rpoB 762599 c.2793T>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoB 762603 p.Cys933Ala missense_variant 0.88 rifampicin
rpoC 762608 c.-762C>G upstream_gene_variant 0.88 rifampicin
rpoB 762814 p.Met1003Arg missense_variant 0.93 rifampicin
rpoB 762818 c.3012C>G synonymous_variant 0.93 rifampicin Not assoc w R - Interim
rpoB 762827 c.3021G>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 762839 c.-531G>A upstream_gene_variant 0.95 rifampicin
rpoC 762851 c.-519C>T upstream_gene_variant 0.95 rifampicin
rpoB 762857 c.3051C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 762863 c.-507T>G upstream_gene_variant 1.0 rifampicin
rpoB 762879 c.3073_3075delATGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 762911 c.-459C>T upstream_gene_variant 1.0 rifampicin
rpoB 762917 c.3111C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762929 c.3123G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 762995 c.3189G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763004 c.3198G>A synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763007 c.3201C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763028 c.3222T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763031 c.3225T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763034 c.3228C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoB 763040 c.3234C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763050 c.-320C>T upstream_gene_variant 0.99 rifampicin
rpoB 763070 c.3264T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763082 c.-288C>G upstream_gene_variant 1.0 rifampicin
rpoB 763085 c.3279C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoB 763115 c.3309T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoB 763127 c.3321G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763139 c.-231C>T upstream_gene_variant 0.98 rifampicin
rpoC 763142 c.-228C>G upstream_gene_variant 0.98 rifampicin
rpoC 763158 c.-212C>T upstream_gene_variant 0.98 rifampicin
rpoB 763166 c.3360A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763202 c.-168A>G upstream_gene_variant 0.94 rifampicin
rpoC 763206 c.-164_-162delAGTinsTCC upstream_gene_variant 0.94 rifampicin
rpoB 763214 c.3408T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 763217 c.-153G>T upstream_gene_variant 0.94 rifampicin
rpoC 763226 c.-144A>G upstream_gene_variant 0.94 rifampicin
rpoB 763227 p.Leu1141Met missense_variant 0.94 rifampicin
rpoC 763232 c.-138C>T upstream_gene_variant 0.94 rifampicin
rpoB 763235 p.Glu1143Asp missense_variant 0.94 rifampicin
rpoB 763238 c.3432T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763241 p.Glu1145Asp missense_variant 0.94 rifampicin
rpoC 763259 c.-111G>C upstream_gene_variant 0.89 rifampicin
rpoC 763262 c.-108C>T upstream_gene_variant 0.89 rifampicin
rpoB 763268 c.3462C>G synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoB 763283 c.3477T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 763284 c.-86C>T upstream_gene_variant 0.91 rifampicin
rpoC 763373 c.4_6delCTCinsTA frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763399 c.30C>T synonymous_variant 1.0 rifampicin
rpoC 763402 c.33C>G synonymous_variant 1.0 rifampicin
rpoC 763405 c.36C>T synonymous_variant 1.0 rifampicin
rpoC 763414 c.45T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763430 c.61_63delAGGinsCT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763433 c.64_66delCAAinsAT frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763443 p.Tyr25Phe missense_variant 1.0 rifampicin
rpoC 763456 c.87A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763468 c.99G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763486 c.117T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763492 c.123G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763504 c.135C>G synonymous_variant 0.98 rifampicin
rpoC 763528 c.159G>A synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763546 c.177A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763570 c.201G>T synonymous_variant 0.98 rifampicin
rpoC 763573 c.204G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 763594 c.225C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 763660 c.291T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763666 c.297G>A synonymous_variant 1.0 rifampicin
rpoC 763675 c.306C>A synonymous_variant 1.0 rifampicin
rpoC 763702 c.333C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763714 c.345G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763732 c.363C>G synonymous_variant 1.0 rifampicin
rpoC 763735 c.366G>C synonymous_variant 1.0 rifampicin
rpoC 763741 c.372C>T synonymous_variant 1.0 rifampicin
rpoC 763744 c.375G>C synonymous_variant 1.0 rifampicin
rpoC 763765 c.396T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763774 c.405G>C synonymous_variant 1.0 rifampicin
rpoC 763781 p.Ser138Glu missense_variant 1.0 rifampicin
rpoC 763790 c.421_423delGAGinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 763807 c.438T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763813 c.444C>G synonymous_variant 1.0 rifampicin
rpoC 763816 c.447C>G synonymous_variant 1.0 rifampicin
rpoC 763822 c.453C>G synonymous_variant 1.0 rifampicin
rpoC 763825 c.456G>A synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763831 c.462A>G synonymous_variant 1.0 rifampicin
rpoC 763840 c.471G>C synonymous_variant 1.0 rifampicin
rpoC 763849 c.480G>A synonymous_variant 1.0 rifampicin
rpoC 763855 c.486C>T synonymous_variant 1.0 rifampicin
rpoC 763858 c.489A>G synonymous_variant 1.0 rifampicin
rpoC 763861 c.492C>T synonymous_variant 1.0 rifampicin
rpoC 763867 c.498C>G synonymous_variant 1.0 rifampicin
rpoC 763870 c.501C>T synonymous_variant 1.0 rifampicin
rpoC 763872 p.Gly168Ala missense_variant 1.0 rifampicin
rpoC 763876 p.Glu169Asp missense_variant 1.0 rifampicin
rpoC 763879 c.510A>G synonymous_variant 1.0 rifampicin
rpoC 763885 c.516C>G synonymous_variant 1.0 rifampicin
rpoC 763888 c.519G>C synonymous_variant 1.0 rifampicin
rpoC 763894 c.525A>G synonymous_variant 1.0 rifampicin
rpoC 763900 c.531G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763930 c.561G>A synonymous_variant 1.0 rifampicin
rpoC 763940 p.Ala191Ser missense_variant 1.0 rifampicin Uncertain significance
rpoC 763947 p.Ala193Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 763951 c.582G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763960 c.591T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 763978 c.609C>T synonymous_variant 1.0 rifampicin
rpoC 763991 p.Ile208Leu missense_variant 1.0 rifampicin
rpoC 763996 c.627T>C synonymous_variant 1.0 rifampicin
rpoC 764005 c.636G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764024 c.655_657delTTGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764032 p.Asp221Glu missense_variant 1.0 rifampicin
rpoC 764040 p.Ser224Asn missense_variant 1.0 rifampicin
rpoC 764044 c.675T>C synonymous_variant 1.0 rifampicin
rpoC 764059 c.690G>T synonymous_variant 1.0 rifampicin
rpoC 764077 c.708C>G synonymous_variant 1.0 rifampicin
rpoC 764083 c.714A>G synonymous_variant 1.0 rifampicin
rpoC 764084 p.Asn239Val missense_variant 1.0 rifampicin
rpoC 764097 c.729_732delACTC frameshift_variant 1.0 rifampicin
rpoC 764104 c.735delCinsTGCAG frameshift_variant&synonymous_variant 1.0 rifampicin
rpoC 764126 p.Thr253Val missense_variant 1.0 rifampicin
rpoC 764131 c.762T>C synonymous_variant 1.0 rifampicin
rpoC 764147 c.778_780delTCGinsGC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764153 p.Gln262Lys missense_variant 1.0 rifampicin
rpoC 764156 p.Lys263Arg missense_variant 1.0 rifampicin
rpoC 764182 p.Asp271Glu missense_variant 1.0 rifampicin Uncertain significance
rpoC 764188 c.819A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764194 p.Glu275Asp missense_variant 1.0 rifampicin
rpoC 764203 c.834G>C synonymous_variant 1.0 rifampicin
rpoC 764206 c.837T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764207 p.Val280Thr missense_variant 1.0 rifampicin Uncertain significance
rpoC 764215 c.846A>T synonymous_variant 1.0 rifampicin
rpoC 764242 c.873C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764245 c.876C>G synonymous_variant 0.98 rifampicin
rpoC 764257 c.888G>C synonymous_variant 0.98 rifampicin
rpoC 764266 c.897T>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764269 c.900G>T synonymous_variant 0.97 rifampicin
rpoC 764272 c.903G>C synonymous_variant 0.97 rifampicin
rpoC 764278 c.909A>G synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764285 p.Gly306Ser missense_variant 0.97 rifampicin
rpoC 764293 c.924G>A synonymous_variant 0.98 rifampicin
rpoC 764320 c.951C>T synonymous_variant 0.97 rifampicin
rpoC 764353 c.984G>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764365 c.996C>T synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764371 c.1002G>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764374 c.1005C>T synonymous_variant 0.98 rifampicin
rpoC 764377 c.1008C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764380 c.1011G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764387 c.1018T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764404 c.1035C>G synonymous_variant 1.0 rifampicin
rpoC 764405 c.1036_1038delAGGinsCC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764431 c.1062G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764434 c.1065A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764438 c.1069_1071delCTGinsTA frameshift_variant&stop_gained 1.0 rifampicin
rpoC 764443 c.1074C>T synonymous_variant 1.0 rifampicin
rpoC 764446 c.1077T>C synonymous_variant 1.0 rifampicin
rpoC 764449 c.1080G>C synonymous_variant 1.0 rifampicin
rpoC 764452 c.1083T>A synonymous_variant 1.0 rifampicin
rpoC 764455 c.1086G>T synonymous_variant 1.0 rifampicin
rpoC 764458 c.1089G>T synonymous_variant 1.0 rifampicin
rpoC 764467 c.1098C>T synonymous_variant 1.0 rifampicin
rpoC 764485 c.1116G>C synonymous_variant 1.0 rifampicin
rpoC 764491 c.1122G>T synonymous_variant 1.0 rifampicin
rpoC 764497 c.1128A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764500 c.1131C>A synonymous_variant 1.0 rifampicin
rpoC 764521 c.1152T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764524 c.1155C>T synonymous_variant 1.0 rifampicin
rpoC 764527 c.1158C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764536 c.1167G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764539 c.1170C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764548 c.1179G>A synonymous_variant 1.0 rifampicin
rpoC 764560 c.1191T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764566 c.1197C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764575 c.1206T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764578 c.1209C>G synonymous_variant 1.0 rifampicin
rpoC 764585 c.1216_1218delCTCinsTG frameshift_variant&missense_variant 1.0 rifampicin
rpoC 764602 c.1233C>T synonymous_variant 1.0 rifampicin
rpoC 764611 c.1242G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764632 c.1263T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764644 c.1275G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764650 c.1281G>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 764713 c.1344G>A synonymous_variant 0.99 rifampicin
rpoC 764716 c.1347G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764746 c.1377G>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764752 c.1383G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764758 c.1389C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764764 c.1395T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764791 c.1422C>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764797 c.1428G>C synonymous_variant 0.99 rifampicin
rpoC 764803 c.1434C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764809 c.1440C>T synonymous_variant 0.99 rifampicin Not assoc w R
rpoC 764815 c.1446A>G synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764824 c.1455T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764827 c.1458G>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764858 c.1489T>C synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764869 c.1500C>T synonymous_variant 0.99 rifampicin Not assoc w R - Interim
rpoC 764875 c.1506C>G synonymous_variant 0.99 rifampicin
rpoC 764878 c.1509C>G synonymous_variant 0.99 rifampicin
rpoC 764887 c.1518G>C synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 764888 c.1519_1521delTTGinsCC frameshift_variant&missense_variant 0.98 rifampicin
rpoC 764911 c.1542A>G synonymous_variant 1.0 rifampicin
rpoC 764912 p.Met515Gln missense_variant 1.0 rifampicin Uncertain significance
rpoC 764923 c.1554A>G synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764948 c.1579T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 764968 c.1599T>C synonymous_variant 0.98 rifampicin Not assoc w R - Interim
rpoC 765004 c.1635G>T synonymous_variant 0.97 rifampicin
rpoC 765007 c.1638T>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765008 c.1639T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765011 c.1642_1643delAGinsTC synonymous_variant 0.96 rifampicin
rpoC 765016 c.1647C>G synonymous_variant 0.96 rifampicin
rpoC 765019 c.1650A>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765034 c.1665T>G synonymous_variant 0.96 rifampicin
rpoC 765040 c.1671T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765041 c.1672T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765047 c.1678T>C synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765052 c.1683C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765055 c.1686C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 765065 c.1696C>T synonymous_variant 0.96 rifampicin
rpoC 765073 c.1704G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765076 c.1707A>G synonymous_variant 1.0 rifampicin
rpoC 765079 c.1710T>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765082 c.1713G>T synonymous_variant 1.0 rifampicin
rpoC 765089 c.1720T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765103 c.1734G>T synonymous_variant 1.0 rifampicin
rpoC 765338 p.Gln657Lys missense_variant 0.82 rifampicin
rpoC 765343 c.1974G>C synonymous_variant 0.85 rifampicin
rpoC 765352 c.1983G>C synonymous_variant 0.88 rifampicin Not assoc w R - Interim
rpoC 765357 p.Met663Thr missense_variant 0.88 rifampicin
rpoC 765367 c.1998C>G synonymous_variant 0.91 rifampicin
rpoC 765385 p.Met672Ile missense_variant 0.94 rifampicin
rpoC 765397 c.2028G>T synonymous_variant 0.94 rifampicin
rpoC 765402 c.2035_2038delCTGG frameshift_variant 0.94 rifampicin
rpoC 765409 c.2041_2042insCAGT frameshift_variant 0.94 rifampicin
rpoC 765425 p.Lys686Glu missense_variant 0.95 rifampicin
rpoC 765451 c.2082C>G synonymous_variant 1.0 rifampicin
rpoC 765452 p.Ala695Arg missense_variant 1.0 rifampicin
rpoC 765458 p.Ile697Val missense_variant 1.0 rifampicin Uncertain significance
rpoC 765466 c.2097C>T synonymous_variant 1.0 rifampicin
rpoC 765478 c.2109T>G synonymous_variant 1.0 rifampicin
rpoC 765496 c.2127C>G synonymous_variant 1.0 rifampicin
rpoC 765499 c.2130C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765793 c.2424C>G synonymous_variant 1.0 rifampicin
rpoC 765796 c.2427C>T synonymous_variant 1.0 rifampicin
rpoC 765805 c.2436C>G synonymous_variant 1.0 rifampicin
rpoC 765811 c.2442T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765814 c.2445A>C synonymous_variant 1.0 rifampicin
rpoC 765826 c.2457T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765835 c.2466C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765875 p.Val836Ile missense_variant 1.0 rifampicin Uncertain significance
rpoC 765886 c.2517C>G synonymous_variant 1.0 rifampicin
rpoC 765892 c.2523T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765898 c.2529C>T synonymous_variant 1.0 rifampicin
rpoC 765904 c.2535C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765937 c.2568T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765946 c.2577C>T synonymous_variant 1.0 rifampicin
rpoC 765947 c.2578T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765961 c.2592G>T synonymous_variant 1.0 rifampicin
rpoC 765962 c.2593_2595delTTGinsCT frameshift_variant&synonymous_variant 1.0 rifampicin
rpoC 765967 c.2598C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765973 c.2604C>G synonymous_variant 1.0 rifampicin
rpoC 765979 c.2610C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765982 c.2613C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765991 c.2622C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 765994 c.2625A>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766003 c.2634G>C synonymous_variant 1.0 rifampicin
rpoC 766009 c.2640G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766010 c.2641_2642delTCinsAG synonymous_variant 1.0 rifampicin
rpoC 766021 c.2652G>C synonymous_variant 1.0 rifampicin
rpoC 766034 p.His889Thr missense_variant 1.0 rifampicin
rpoC 766043 p.Gln892Glu missense_variant 1.0 rifampicin
rpoC 766369 c.3000C>G synonymous_variant 0.91 rifampicin
rpoC 766384 c.3015A>G synonymous_variant 0.95 rifampicin
rpoC 766393 c.3024C>G synonymous_variant 0.95 rifampicin
rpoC 766397 c.3028C>T synonymous_variant 0.95 rifampicin
rpoC 766408 c.3039C>T synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 766411 c.3042C>G synonymous_variant 0.95 rifampicin
rpoC 766423 c.3054T>C synonymous_variant 0.95 rifampicin
rpoC 766428 c.3060_3061insACCGGC conservative_inframe_insertion 0.95 rifampicin
rpoC 766433 p.Glu1022Ser missense_variant 0.95 rifampicin
rpoC 766438 c.3069C>T synonymous_variant 0.95 rifampicin
rpoC 766456 c.3087C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766459 c.3090G>C synonymous_variant 1.0 rifampicin
rpoC 766480 c.3111C>G synonymous_variant 1.0 rifampicin
rpoC 766483 c.3114G>C synonymous_variant 1.0 rifampicin
rpoC 766484 c.3115_3117delGTAinsAC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766492 c.3123T>G synonymous_variant 1.0 rifampicin
rpoC 766494 p.Gly1042Asp missense_variant 1.0 rifampicin Uncertain significance
rpoC 766517 p.Thr1050Ser missense_variant 1.0 rifampicin
rpoC 766522 c.3153C>T synonymous_variant 1.0 rifampicin
rpoC 766540 p.Asp1057Glu missense_variant 1.0 rifampicin
rpoC 766645 c.3276A>G synonymous_variant 0.9 rifampicin
rpoC 766652 p.Ser1095Thr missense_variant 0.93 rifampicin
rpoC 766657 c.3288A>G synonymous_variant 0.93 rifampicin
rpoC 766661 p.Val1098Leu missense_variant 1.0 rifampicin
rpoC 766667 p.Ser1100Ala missense_variant 1.0 rifampicin Uncertain significance
rpoC 766672 c.3303T>C synonymous_variant 1.0 rifampicin
rpoC 766693 c.3324C>T synonymous_variant 1.0 rifampicin
rpoC 766714 c.3345G>C synonymous_variant 1.0 rifampicin
rpoC 766726 c.3357T>C synonymous_variant 1.0 rifampicin
rpoC 766733 c.3364C>T synonymous_variant 1.0 rifampicin
rpoC 766738 c.3369G>T synonymous_variant 1.0 rifampicin
rpoC 766741 c.3372G>C synonymous_variant 1.0 rifampicin
rpoC 766750 c.3381C>G synonymous_variant 1.0 rifampicin
rpoC 766765 c.3396A>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766771 c.3402G>C synonymous_variant 1.0 rifampicin
rpoC 766774 c.3405T>C synonymous_variant 1.0 rifampicin
rpoC 766775 p.Arg1136Lys missense_variant 1.0 rifampicin
rpoC 766801 c.3432C>T synonymous_variant 1.0 rifampicin
rpoC 766804 c.3435A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766843 c.3474T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766846 c.3477C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766931 c.3562_3564delGCAinsTC frameshift_variant&missense_variant 1.0 rifampicin
rpoC 766942 c.3573C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766945 c.3576A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766951 c.3582G>C synonymous_variant 1.0 rifampicin
rpoC 766963 c.3594T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766978 c.3609C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 766996 c.3627C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767002 c.3633G>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767023 c.3654C>T synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767033 c.3664_3666delTCGinsAGC synonymous_variant 1.0 rifampicin
rpoC 767098 c.3729T>C synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767104 c.3735C>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767106 p.Asn1246Met missense_variant 1.0 rifampicin
rpoC 767119 c.3750A>G synonymous_variant 1.0 rifampicin Not assoc w R - Interim
rpoC 767155 c.3786C>G synonymous_variant 0.98 rifampicin
rpoC 767180 p.Ala1271Gln missense_variant 0.97 rifampicin
rpoC 767186 p.Gln1273Glu missense_variant 0.97 rifampicin
rpoC 767197 c.3828G>A synonymous_variant 0.97 rifampicin Not assoc w R - Interim
rpoC 767206 c.3837C>T synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767209 c.3840T>C synonymous_variant 0.92 rifampicin Not assoc w R - Interim
rpoC 767212 c.3843G>T synonymous_variant 0.92 rifampicin
rpoC 767221 c.3852C>G synonymous_variant 0.96 rifampicin Not assoc w R - Interim
rpoC 767230 c.3861G>C synonymous_variant 0.95 rifampicin Not assoc w R - Interim
rpoC 767233 c.3864T>C synonymous_variant 0.94 rifampicin Not assoc w R - Interim
rpoC 767263 c.3894T>C synonymous_variant 0.91 rifampicin Not assoc w R - Interim
rpoC 767264 p.Ala1299Gln missense_variant 0.91 rifampicin
rpoC 767278 c.3909T>G synonymous_variant 0.9 rifampicin
mmpL5 775847 c.2634G>C synonymous_variant 0.92 clofazimine
bedaquiline
mmpL5 775856 c.2625T>C synonymous_variant 0.94 clofazimine
bedaquiline
mmpL5 775865 c.2616T>G synonymous_variant 0.95 clofazimine
bedaquiline
mmpL5 775886 c.2595A>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775895 c.2584_2586delATCinsCG frameshift_variant&missense_variant 0.93 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775898 c.2583G>A synonymous_variant 0.93 clofazimine
bedaquiline
mmpL5 775910 c.2571G>C synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775913 c.2568C>G synonymous_variant 0.88 clofazimine
bedaquiline
mmpL5 775916 c.2565T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 775924 c.2557C>T synonymous_variant 0.84 clofazimine Not assoc w R - Interim
bedaquiline
mmpL5 775937 c.2544G>C synonymous_variant 0.86 clofazimine
bedaquiline
mmpL5 775946 c.2535C>G synonymous_variant 0.91 clofazimine
bedaquiline
mmpL5 775951 c.2530C>T synonymous_variant 0.76 clofazimine
bedaquiline
mmpL5 775961 c.2520C>G synonymous_variant 0.36 clofazimine
bedaquiline
mmpL5 775966 p.Ala839Ser missense_variant 0.79 clofazimine
bedaquiline
mmpL5 775975 p.Leu836Met missense_variant 0.93 clofazimine
bedaquiline
mmpL5 775981 p.Leu834Met missense_variant 1.0 clofazimine
bedaquiline
mmpL5 775991 p.Glu830Asp missense_variant 0.91 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 775997 c.2484T>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776005 p.Ile826Leu missense_variant 0.8 clofazimine
bedaquiline
mmpL5 776009 c.2472A>G synonymous_variant 0.8 clofazimine
bedaquiline
mmpL5 776015 c.2464_2466delATCinsCG frameshift_variant&missense_variant 0.48 clofazimine Uncertain significance
bedaquiline Uncertain significance
mmpL5 776027 c.2454G>C synonymous_variant 0.43 clofazimine
bedaquiline
mmpL5 776030 c.2451G>C synonymous_variant 0.5 clofazimine
bedaquiline
mmpL5 776039 c.2442C>G synonymous_variant 0.63 clofazimine
bedaquiline
mmpL5 776053 c.2428T>C synonymous_variant 0.67 clofazimine
bedaquiline
mmpL5 776072 c.2409C>G synonymous_variant 0.51 clofazimine
bedaquiline
mmpL5 776075 p.Ala802Val missense_variant 0.6 clofazimine
bedaquiline
mmpL5 776081 c.2400G>C synonymous_variant 0.58 clofazimine
bedaquiline
mmpL5 776084 c.2397C>G synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 776087 p.Val798Ala missense_variant 0.96 clofazimine
bedaquiline
mmpL5 776090 c.2391C>T synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 776093 c.2388C>A synonymous_variant 0.53 clofazimine
bedaquiline
mmpL5 776100 p.Thr794Ile missense_variant 1.0 clofazimine Not assoc w R
bedaquiline Not assoc w R - Interim
mmpL5 776104 p.Ile793Leu missense_variant 0.55 clofazimine
bedaquiline
mmpL5 777020 c.1461G>C synonymous_variant 1.0 clofazimine
bedaquiline
mmpL5 777047 c.1434A>C synonymous_variant 1.0 clofazimine
bedaquiline
rpsL 781631 c.72G>C synonymous_variant 0.94 streptomycin
rpsL 781649 c.90T>C synonymous_variant 0.96 streptomycin
rpsL 781655 c.96T>C synonymous_variant 0.95 streptomycin
rpsL 781658 c.99A>G synonymous_variant 0.96 streptomycin
rpsL 781682 c.123T>C synonymous_variant 0.98 streptomycin
rpsL 781715 c.156T>C synonymous_variant 0.98 streptomycin
rpsL 781718 c.159C>G synonymous_variant 0.98 streptomycin
rpsL 781724 c.165G>C synonymous_variant 0.98 streptomycin
rpsL 781728 c.169T>C synonymous_variant 0.98 streptomycin
rpsL 781736 c.177T>C synonymous_variant 0.98 streptomycin
rpsL 781742 c.183C>T synonymous_variant 0.98 streptomycin
rpsL 781751 c.192G>C synonymous_variant 0.98 streptomycin
rpsL 781754 c.195G>T synonymous_variant 0.98 streptomycin
rpsL 781760 c.201T>C synonymous_variant 0.98 streptomycin
rpsL 781769 c.210G>A synonymous_variant 0.98 streptomycin
rpsL 781814 c.255C>T synonymous_variant 1.0 streptomycin
rpsL 781817 c.258G>T synonymous_variant 1.0 streptomycin
rpsL 781832 c.273T>G synonymous_variant 1.0 streptomycin
rpsL 781865 c.306G>C synonymous_variant 1.0 streptomycin
rpsL 781868 c.309T>C synonymous_variant 1.0 streptomycin
rpsL 781871 c.312G>C synonymous_variant 1.0 streptomycin
rpsL 781880 c.321C>G synonymous_variant 0.99 streptomycin
rpsL 781892 c.333A>G synonymous_variant 0.98 streptomycin
rpsL 781904 c.345C>T synonymous_variant 0.98 streptomycin Not assoc w R - Interim
rpsL 781916 c.357T>C synonymous_variant 0.98 streptomycin
rpsL 781929 p.Gly124Ser missense_variant 0.97 streptomycin Uncertain significance
rplC 800516 c.-293G>C upstream_gene_variant 1.0 linezolid
rplC 800537 c.-272C>G upstream_gene_variant 1.0 linezolid
rplC 800540 c.-269T>C upstream_gene_variant 1.0 linezolid
rplC 800546 c.-263T>C upstream_gene_variant 1.0 linezolid
rplC 800567 c.-242A>G upstream_gene_variant 1.0 linezolid
rplC 800570 c.-239C>G upstream_gene_variant 1.0 linezolid
rplC 800574 c.-235_-234delGTinsAC upstream_gene_variant 1.0 linezolid
rplC 800582 c.-227C>G upstream_gene_variant 1.0 linezolid
rplC 800585 c.-224T>C upstream_gene_variant 1.0 linezolid
rplC 800594 c.-215C>G upstream_gene_variant 1.0 linezolid
rplC 800597 c.-212A>C upstream_gene_variant 1.0 linezolid
rplC 800600 c.-209G>C upstream_gene_variant 1.0 linezolid
rplC 800612 c.-197A>G upstream_gene_variant 1.0 linezolid
rplC 800618 c.-191T>C upstream_gene_variant 1.0 linezolid
rplC 800627 c.-182C>T upstream_gene_variant 1.0 linezolid
rplC 800633 c.-176T>C upstream_gene_variant 1.0 linezolid
rplC 800702 c.-107G>A upstream_gene_variant 1.0 linezolid
rplC 800703 c.-106T>C upstream_gene_variant 1.0 linezolid
rplC 800715 c.-94A>C upstream_gene_variant 1.0 linezolid
rplC 800720 c.-89T>C upstream_gene_variant 1.0 linezolid
rplC 800723 c.-86C>G upstream_gene_variant 1.0 linezolid
rplC 800735 c.-74C>G upstream_gene_variant 1.0 linezolid
rplC 800738 c.-71T>C upstream_gene_variant 1.0 linezolid
rplC 800759 c.-50C>T upstream_gene_variant 1.0 linezolid
rplC 800762 c.-47T>G upstream_gene_variant 1.0 linezolid
rplC 800771 c.-38C>T upstream_gene_variant 1.0 linezolid
rplC 800774 c.-35C>T upstream_gene_variant 1.0 linezolid
rplC 800799 c.-10_-8delGGAinsC upstream_gene_variant 1.0 linezolid
rplC 800807 c.-2C>A upstream_gene_variant 1.0 linezolid
rplC 800814 c.6A>T synonymous_variant 1.0 linezolid
rplC 800815 c.7_9delCGAinsAG frameshift_variant&synonymous_variant 1.0 linezolid
rplC 800819 p.Lys4Arg missense_variant 1.0 linezolid
rplC 800829 c.21C>G synonymous_variant 1.0 linezolid
rplC 800832 c.24T>C synonymous_variant 1.0 linezolid
rplC 800844 c.36T>C synonymous_variant 1.0 linezolid
rplC 800856 c.48A>G synonymous_variant 1.0 linezolid
rplC 800865 c.57A>G synonymous_variant 1.0 linezolid
rplC 800867 p.Ser20Asn missense_variant 1.0 linezolid
rplC 800874 c.66A>G synonymous_variant 1.0 linezolid
rplC 800877 c.69A>C synonymous_variant 1.0 linezolid
rplC 800880 c.72A>G synonymous_variant 1.0 linezolid
rplC 800889 c.81C>G synonymous_variant 1.0 linezolid
rplC 800892 c.84G>C synonymous_variant 1.0 linezolid
rplC 800904 c.96G>C synonymous_variant 1.0 linezolid
rplC 800913 c.105G>C synonymous_variant 1.0 linezolid
rplC 800916 c.108A>C synonymous_variant 1.0 linezolid
rplC 800919 c.111C>G synonymous_variant 1.0 linezolid
rplC 800922 c.114C>T synonymous_variant 1.0 linezolid
rplC 800931 c.123G>C synonymous_variant 1.0 linezolid
rplC 800932 p.Pro42Ala missense_variant 1.0 linezolid
rplC 800937 c.129A>G synonymous_variant 1.0 linezolid
rplC 800946 c.138T>C synonymous_variant 1.0 linezolid
rplC 800949 c.141T>C synonymous_variant 1.0 linezolid
rplC 800970 c.162T>C synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800973 c.165C>T synonymous_variant 1.0 linezolid Not assoc w R - Interim
rplC 800981 p.Ser58Asn missense_variant 1.0 linezolid
rplC 800985 c.177A>G synonymous_variant 1.0 linezolid
rplC 800994 c.186C>G synonymous_variant 1.0 linezolid
rplC 800996 p.Asn63Thr missense_variant 1.0 linezolid
rplC 801117 c.309G>C synonymous_variant 0.9 linezolid
rplC 801127 p.Ala107Ser missense_variant 0.92 linezolid
rplC 801132 c.324T>C synonymous_variant 0.92 linezolid
rplC 801147 c.339T>C synonymous_variant 0.93 linezolid
rplC 801156 c.348T>C synonymous_variant 0.94 linezolid
rplC 801160 c.352_353delTCinsAG synonymous_variant 0.94 linezolid
rplC 801171 c.363A>G synonymous_variant 0.95 linezolid
rplC 801174 c.366T>C synonymous_variant 0.95 linezolid
rplC 801180 c.372C>G synonymous_variant 0.95 linezolid
rplC 801186 c.378C>G synonymous_variant 0.95 linezolid
rplC 801195 c.387G>C synonymous_variant 0.95 linezolid
rplC 801201 c.393C>T synonymous_variant 0.95 linezolid
rplC 801204 c.396C>T synonymous_variant 0.95 linezolid
rplC 801205 p.Arg133Ser missense_variant 0.95 linezolid
rplC 801210 c.402T>C synonymous_variant 0.95 linezolid
rplC 801222 c.414T>C synonymous_variant 0.92 linezolid
rplC 801228 c.420T>C synonymous_variant 0.92 linezolid
rplC 801252 c.444G>C synonymous_variant 0.96 linezolid
rplC 801255 c.447C>T synonymous_variant 0.96 linezolid
rplC 801267 c.459A>C synonymous_variant 0.96 linezolid
rplC 801270 c.462T>C synonymous_variant 0.96 linezolid
rplC 801273 c.465C>G synonymous_variant 0.95 linezolid
rplC 801281 p.Ala158Gly missense_variant 0.95 linezolid
rplC 801309 c.501C>G synonymous_variant 0.93 linezolid
rplC 801312 c.504G>C synonymous_variant 0.93 linezolid
fbiC 1303488 c.558G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303492 c.562T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303509 c.579G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303512 c.582T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303531 p.Met201Leu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303545 c.615A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303554 c.624G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303560 c.630G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303581 c.651G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303584 c.654C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303590 c.660A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303593 c.663G>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303611 c.681G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303614 c.684C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303632 c.702T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303638 c.708A>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303641 c.711C>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303646 p.Ala239Glu missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303650 c.720G>T synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1303659 c.729T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303660 p.Val244Thr missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303666 p.Thr246Ala missense_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303681 c.751T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1303689 c.759T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304499 c.1569T>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid
fbiC 1304508 p.Glu526Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304520 c.1590A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304526 c.1596T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304533 c.1603T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304538 c.1608C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304541 c.1611C>A synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304545 p.Val539Thr missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304559 p.Glu543Asp missense_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304562 c.1632G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304565 c.1635C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304568 c.1638T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304571 c.1641G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304580 c.1650T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304613 c.1683T>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304640 c.1710A>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304646 c.1716T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304658 c.1728C>G synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304670 c.1740G>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304675 p.Gly582Asp missense_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304694 c.1764A>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304703 c.1773C>G synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304709 c.1779C>G synonymous_variant 0.98 clofazimine
pretomanid
delamanid
fbiC 1304715 c.1785G>T synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304724 c.1794A>G synonymous_variant 0.97 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
fbiC 1304727 c.1797A>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304742 c.1812T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304748 c.1818T>C synonymous_variant 0.97 clofazimine
pretomanid
delamanid
fbiC 1304754 c.1824G>A synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304757 c.1827A>G synonymous_variant 0.95 clofazimine
pretomanid
delamanid
fbiC 1304763 c.1833C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304766 c.1836C>G synonymous_variant 0.94 clofazimine
pretomanid
delamanid
fbiC 1304778 c.1848T>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304781 c.1851G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304784 c.1854T>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304787 c.1857T>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304796 c.1866G>A synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304799 c.1869G>C synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304808 c.1878C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304811 c.1881C>G synonymous_variant 0.93 clofazimine
pretomanid
delamanid
fbiC 1304817 c.1887T>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304826 c.1896G>C synonymous_variant 1.0 clofazimine
pretomanid
delamanid
fbiC 1304832 c.1902C>G synonymous_variant 1.0 clofazimine Not assoc w R - Interim
pretomanid
delamanid Not assoc w R - Interim
sigE 1364691 c.279T>C synonymous_variant 1.0 pyrazinamide
sigE 1364703 c.291G>C synonymous_variant 1.0 pyrazinamide
sigE 1364709 c.297T>C synonymous_variant 1.0 pyrazinamide
sigE 1364712 c.300T>C synonymous_variant 1.0 pyrazinamide
sigE 1364721 c.309C>G synonymous_variant 1.0 pyrazinamide
sigE 1364736 c.324T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
sigE 1364742 c.330A>G synonymous_variant 1.0 pyrazinamide
sigE 1364763 c.351T>C synonymous_variant 1.0 pyrazinamide
sigE 1364767 c.355_357delAGGinsCC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364772 c.360G>C synonymous_variant 1.0 pyrazinamide
sigE 1364781 c.369G>C synonymous_variant 1.0 pyrazinamide
sigE 1364784 c.372C>G synonymous_variant 1.0 pyrazinamide
sigE 1364790 c.378T>C synonymous_variant 1.0 pyrazinamide
sigE 1364799 c.387G>C synonymous_variant 1.0 pyrazinamide
sigE 1364805 c.393C>G synonymous_variant 1.0 pyrazinamide
sigE 1364811 c.399A>G synonymous_variant 1.0 pyrazinamide
sigE 1364820 c.408A>G synonymous_variant 1.0 pyrazinamide
sigE 1364835 c.423C>G synonymous_variant 1.0 pyrazinamide
sigE 1364839 c.427T>C synonymous_variant 1.0 pyrazinamide
sigE 1364844 c.432C>T synonymous_variant 1.0 pyrazinamide
sigE 1364847 c.435G>C synonymous_variant 1.0 pyrazinamide
sigE 1364860 c.448_450delCGCinsAG frameshift_variant&missense_variant 0.97 pyrazinamide Uncertain significance
sigE 1364865 c.453G>C synonymous_variant 0.97 pyrazinamide
sigE 1364867 p.Ala152Gly missense_variant 1.0 pyrazinamide
sigE 1364883 c.471G>A synonymous_variant 1.0 pyrazinamide
sigE 1364887 c.475_477delTTAinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
sigE 1364919 p.Asp169Glu missense_variant 1.0 pyrazinamide
sigE 1364922 p.Glu170Asp missense_variant 1.0 pyrazinamide
sigE 1364950 p.Ala180Ser missense_variant 0.97 pyrazinamide
sigE 1364956 c.544C>T synonymous_variant 0.96 pyrazinamide
sigE 1364961 c.549A>T synonymous_variant 0.96 pyrazinamide
sigE 1364976 c.564T>C synonymous_variant 0.94 pyrazinamide Not assoc w R - Interim
sigE 1364979 c.567C>G synonymous_variant 0.94 pyrazinamide
sigE 1364980 c.568T>C synonymous_variant 0.94 pyrazinamide
sigE 1364984 p.Ala191Asp missense_variant 0.94 pyrazinamide
sigE 1365003 c.591T>C synonymous_variant 0.94 pyrazinamide
sigE 1365006 c.594T>C synonymous_variant 0.94 pyrazinamide
sigE 1365015 c.603G>C synonymous_variant 0.94 pyrazinamide
sigE 1365018 c.606G>C synonymous_variant 0.94 pyrazinamide
sigE 1365024 c.612T>C synonymous_variant 0.94 pyrazinamide
sigE 1365027 c.615C>T synonymous_variant 0.94 pyrazinamide
sigE 1365036 c.624T>C synonymous_variant 0.93 pyrazinamide
rrs 1471923 n.78T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471925 n.80T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471926 n.81C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471932 n.87A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471934 n.89A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1471936 n.91A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1471986 n.141C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472019 n.174G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472029 n.184C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472053 n.211_212delGC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472061 n.216A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472075 n.230A>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472108 n.263C>T non_coding_transcript_exon_variant 0.99 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472279 n.434T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472286 n.441C>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472287 n.442C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472289 n.444T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472298 n.453_468delGTCCGGGTTCTCTCGGinsCGTA non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472315 n.470T>G non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472327 n.482G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472328 n.483G>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin
capreomycin
amikacin
rrs 1472438 n.593T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472446 n.601T>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472452 n.607G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472453 n.608G>A non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472456 n.611T>C non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472459 n.614C>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin
capreomycin
amikacin
rrs 1472464 n.619A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472489 n.644A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472969 n.1124A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472973 n.1128A>T non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1472978 n.1133T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473104 n.1259C>T non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473110 n.1265T>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473111 n.1266A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473123 n.1278delAinsTC non_coding_transcript_exon_variant 1.0 streptomycin
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473276 n.1431A>G non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrs 1473301 n.1456T>C non_coding_transcript_exon_variant 1.0 streptomycin Uncertain significance
kanamycin Uncertain significance
capreomycin Uncertain significance
amikacin Uncertain significance
rrl 1473728 n.71A>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1473746 n.89T>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473770 n.113T>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473788 n.131A>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473806 n.149C>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473807 n.150T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1473812 n.155G>A non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473813 n.156C>G non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1473814 n.157A>C non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473815 n.158T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1473822 n.165A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473829 n.172G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473830 n.173T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1473831 n.174G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473832 n.175C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1473836 n.179A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1473876 n.219G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473887 n.230delTinsCA non_coding_transcript_exon_variant 0.95 capreomycin
linezolid
rrl 1473898 n.241C>T non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1473899 n.242A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474140 n.483C>T non_coding_transcript_exon_variant 0.9 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474151 n.494C>T non_coding_transcript_exon_variant 0.93 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474174 n.517A>G non_coding_transcript_exon_variant 0.94 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474179 n.523dupT non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474184 n.527C>A non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474185 n.529delA non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1474287 n.630_646delTCCTTTTCCTCTCCGGAinsCTCGACTTT non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474305 n.648G>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474306 n.649A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474308 n.651G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474310 n.653T>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1474362 n.705A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474374 n.717T>G non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1474413 n.756_757delACinsTAT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474421 n.764_767delGCGCinsA non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474432 n.775C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474438 n.781delAinsGT non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474439 n.782A>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474446 n.789C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474552 n.895C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474626 n.969T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474627 n.970G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474629 n.972G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474632 n.975G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474636 n.979A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474637 n.980C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474638 n.981C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474639 n.982G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474640 n.983C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1474710 n.1053T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474711 n.1054G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474712 n.1055G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474713 n.1056T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474715 n.1058T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474717 n.1060_1061insG non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474720 n.1063C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1474760 n.1103A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474794 n.1137C>T non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474812 n.1155G>A non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474830 n.1173A>G non_coding_transcript_exon_variant 0.99 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1474952 n.1295_1296insG non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474957 n.1300C>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474958 n.1301A>C non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474960 n.1303C>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474970 n.1313G>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474971 n.1314T>G non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474972 n.1315G>T non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1474990 n.1333C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474991 n.1334T>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474995 n.1338T>C non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474997 n.1340A>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1474999 n.1342C>T non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475008 n.1351C>A non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475010 n.1353G>A non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475015 n.1358_1360delCCGinsTCTA non_coding_transcript_exon_variant 0.96 capreomycin
linezolid
rrl 1475031 n.1374G>T non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475061 n.1404C>T non_coding_transcript_exon_variant 0.97 capreomycin Uncertain significance
linezolid
rrl 1475088 n.1431A>G non_coding_transcript_exon_variant 0.94 capreomycin
linezolid
rrl 1475315 n.1658A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475333 n.1676T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475355 n.1698C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475366 n.1709G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475369 n.1712G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475379 n.1722G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475380 n.1723C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475381 n.1724G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475382 n.1725A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475395 n.1738T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475396 n.1739C>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475397 n.1740G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475398 n.1741C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475403 n.1746T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475404 n.1747A>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475419 n.1762C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475429 n.1772G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475430 n.1773T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475452 n.1795C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475458 n.1801C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475460 n.1803A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475479 n.1822C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475480 n.1823A>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475483 n.1826C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475505 n.1848G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475526 n.1869C>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475544 n.1887A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475545 n.1888T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475602 n.1945G>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475603 n.1946G>C non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475605 n.1948A>T non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475608 n.1951T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475612 n.1955G>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475621 n.1964T>C non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475629 n.1972_1973insC non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475637 n.1980T>A non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475638 n.1981C>G non_coding_transcript_exon_variant 0.96 capreomycin Uncertain significance
linezolid
rrl 1475639 n.1982C>G non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid
rrl 1475643 n.1986C>G non_coding_transcript_exon_variant 0.98 capreomycin
linezolid
rrl 1475647 n.1990G>C non_coding_transcript_exon_variant 0.97 capreomycin
linezolid
rrl 1475659 n.2002G>A non_coding_transcript_exon_variant 0.98 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475756 n.2099T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1475884 n.2227A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475916 n.2259C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1475988 n.2331A>G non_coding_transcript_exon_variant 1.0 capreomycin Not assoc w R
linezolid Uncertain significance
rrl 1475991 n.2334T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1475995 n.2338G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476025 n.2368G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid Uncertain significance
rrl 1476030 n.2373A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476032 n.2375C>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476033 n.2376T>G non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476034 n.2377C>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476035 n.2378G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476044 n.2387T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476045 n.2388G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476046 n.2389G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476047 n.2390G>T non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476049 n.2392C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476088 n.2431A>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476103 n.2446C>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476105 n.2448G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476106 n.2449A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476110 n.2453G>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476115 n.2458T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476165 n.2508T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476214 n.2557G>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476215 n.2558C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476224 n.2567A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476251 n.2594T>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476252 n.2595T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476256 n.2599A>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476281 n.2624T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476529 n.2872A>G non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476583 n.2926G>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476597 n.2940G>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476628 n.2971T>A non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476664 n.3007T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476665 n.3008T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476674 n.3017T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid Uncertain significance
rrl 1476679 n.3022T>C non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476690 n.3033C>T non_coding_transcript_exon_variant 1.0 capreomycin Uncertain significance
linezolid
rrl 1476691 n.3034T>C non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476692 n.3035T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476693 n.3036G>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
rrl 1476723 n.3066T>A non_coding_transcript_exon_variant 1.0 capreomycin
linezolid
inhA 1674443 p.Ala81Val missense_variant 0.8 ethionamide
isoniazid
inhA 1674450 c.249G>C synonymous_variant 0.8 ethionamide
isoniazid
inhA 1674452 p.Ala84Glu missense_variant 0.8 ethionamide
isoniazid
inhA 1674471 c.270G>T synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674480 c.279T>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674486 c.285T>C synonymous_variant 0.88 ethionamide
isoniazid
inhA 1674502 c.301_303delACCinsTG frameshift_variant&missense_variant 0.9 ethionamide
isoniazid
inhA 1674542 p.Ala114Glu missense_variant 0.96 ethionamide
isoniazid
inhA 1674549 c.348G>C synonymous_variant 0.96 ethionamide
isoniazid
inhA 1674550 p.Ser117Ala missense_variant 0.96 ethionamide
isoniazid
inhA 1674575 p.Tyr125Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674582 c.381T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674585 c.384T>G synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674589 p.Met130Leu missense_variant 1.0 ethionamide
isoniazid
inhA 1674601 p.Leu134Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674620 p.Pro140Arg missense_variant 1.0 ethionamide
isoniazid
inhA 1674624 c.423A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674627 c.426T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674628 c.427_428delTCinsAG synonymous_variant 0.98 ethionamide
isoniazid
inhA 1674654 c.453G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674656 p.Ser152Thr missense_variant 1.0 ethionamide
isoniazid
inhA 1674660 c.459G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674672 c.471C>A synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674690 c.489C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674703 c.502T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674711 c.510G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674718 c.517A>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674729 c.528G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674732 c.531C>T synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674738 c.537C>A synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674741 c.540C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674742 p.Lys181Pro missense_variant 1.0 ethionamide
isoniazid
inhA 1674746 p.Tyr182Phe missense_variant 1.0 ethionamide
isoniazid
inhA 1674750 c.549T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674756 c.555T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674759 c.558G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674780 c.579T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674783 c.582C>T synonymous_variant 1.0 ethionamide
isoniazid Not assoc w R - Interim
inhA 1674786 c.585G>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674816 c.615T>C synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674822 c.621C>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674827 p.Glu209Ala missense_variant 1.0 ethionamide
isoniazid
inhA 1674837 c.636C>T synonymous_variant 1.0 ethionamide Not assoc w R - Interim
isoniazid Not assoc w R - Interim
inhA 1674839 p.Ala213Glu missense_variant 1.0 ethionamide
isoniazid
inhA 1674846 p.Ile215Met missense_variant 1.0 ethionamide
isoniazid
inhA 1674848 p.Gln216Arg missense_variant 1.0 ethionamide
isoniazid Uncertain significance
inhA 1674870 c.669T>C synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674879 c.678T>G synonymous_variant 1.0 ethionamide
isoniazid
inhA 1674883 p.Ile228Val missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674892 p.Asn231Asp missense_variant 1.0 ethionamide Uncertain significance
isoniazid Uncertain significance
inhA 1674904 c.703_705delGCGinsCC frameshift_variant&missense_variant 1.0 ethionamide
isoniazid
rpsA 1833537 c.-5_-1delACAATinsCCAC upstream_gene_variant 1.0 pyrazinamide
rpsA 1833547 c.6G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833554 p.Thr5Ser missense_variant 1.0 pyrazinamide
rpsA 1833568 c.27G>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1833589 c.48A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833595 c.54T>G synonymous_variant 1.0 pyrazinamide
rpsA 1833616 c.75A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833619 c.78A>C synonymous_variant 1.0 pyrazinamide
rpsA 1833628 c.87G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833634 c.93G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833664 c.123C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833676 c.135A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833679 c.138G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833685 c.144G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833694 c.153G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833697 c.156C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833709 c.168C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833727 c.186G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833733 c.192C>G synonymous_variant 0.98 pyrazinamide
rpsA 1833734 p.Ala65Ser missense_variant 1.0 pyrazinamide
rpsA 1833739 c.198C>A synonymous_variant 1.0 pyrazinamide
rpsA 1833745 c.204G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833787 c.246C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833790 c.249T>C synonymous_variant 1.0 pyrazinamide
rpsA 1833793 c.252C>T synonymous_variant 1.0 pyrazinamide
rpsA 1833811 c.270G>C synonymous_variant 1.0 pyrazinamide
rpsA 1833829 c.288A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833832 c.291G>A synonymous_variant 1.0 pyrazinamide
rpsA 1833841 c.300C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833847 c.306C>G synonymous_variant 1.0 pyrazinamide
rpsA 1833856 c.315A>G synonymous_variant 1.0 pyrazinamide
rpsA 1833862 c.321G>T synonymous_variant 1.0 pyrazinamide
rpsA 1833874 c.333T>C synonymous_variant 0.98 pyrazinamide
rpsA 1833892 c.351G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833894 p.Ala118Glu missense_variant 0.98 pyrazinamide
rpsA 1833904 c.363G>A synonymous_variant 0.98 pyrazinamide
rpsA 1833928 c.387G>C synonymous_variant 0.96 pyrazinamide
rpsA 1833949 c.408T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833970 c.429G>C synonymous_variant 0.97 pyrazinamide
rpsA 1833979 c.438T>C synonymous_variant 0.97 pyrazinamide
rpsA 1833991 c.450C>G synonymous_variant 0.97 pyrazinamide
rpsA 1834000 c.459G>C synonymous_variant 0.97 pyrazinamide
rpsA 1834009 c.468C>T synonymous_variant 0.97 pyrazinamide
rpsA 1834012 c.471G>T synonymous_variant 0.97 pyrazinamide
rpsA 1834015 c.474G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834021 c.480C>T synonymous_variant 0.98 pyrazinamide
rpsA 1834030 c.489C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834067 c.526C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834097 c.556_557delTCinsAG synonymous_variant 1.0 pyrazinamide
rpsA 1834102 c.561T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834105 c.564C>G synonymous_variant 1.0 pyrazinamide
rpsA 1834150 c.609G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834153 c.612T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834154 c.613_615delAACinsCG frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834157 c.616T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834162 c.621A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834165 c.624A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834169 p.Thr210Ala missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834177 c.636A>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834183 c.642T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834186 c.645C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834189 c.648G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834222 c.681T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834231 c.690T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834234 c.693G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834240 c.699T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834249 c.708T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834261 c.720A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834264 c.723G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834294 c.753G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834303 c.762T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834306 c.765T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834339 c.798C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834348 c.807T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834366 c.825A>G synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834375 c.834G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834378 c.837T>C synonymous_variant 1.0 pyrazinamide Not assoc w R - Interim
rpsA 1834387 c.846C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834396 c.855G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834408 c.867C>T synonymous_variant 1.0 pyrazinamide
rpsA 1834411 c.870T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834423 c.882G>C synonymous_variant 1.0 pyrazinamide
rpsA 1834451 c.910T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834456 c.915T>G synonymous_variant 1.0 pyrazinamide
rpsA 1834465 c.924T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834468 c.927A>G synonymous_variant 1.0 pyrazinamide
rpsA 1834489 c.948T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834513 c.972C>G synonymous_variant 0.99 pyrazinamide
rpsA 1834520 p.Ala327Ser missense_variant 0.99 pyrazinamide
rpsA 1834528 c.987T>C synonymous_variant 0.99 pyrazinamide
rpsA 1834540 c.999G>T synonymous_variant 0.99 pyrazinamide Not assoc w R - Interim
rpsA 1834546 c.1005T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834554 c.1014_1015delTG frameshift_variant 0.98 pyrazinamide Uncertain significance
rpsA 1834558 c.1017_1018insAG frameshift_variant 0.98 pyrazinamide Uncertain significance
rpsA 1834606 c.1065C>G synonymous_variant 0.98 pyrazinamide
rpsA 1834609 c.1068T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834612 c.1071G>C synonymous_variant 0.98 pyrazinamide
rpsA 1834619 c.1078T>C synonymous_variant 0.98 pyrazinamide
rpsA 1834633 c.1092A>G synonymous_variant 0.98 pyrazinamide
rpsA 1834639 c.1098T>C synonymous_variant 1.0 pyrazinamide
rpsA 1834650 p.Thr370Ile missense_variant 1.0 pyrazinamide
rpsA 1834654 c.1113G>A synonymous_variant 1.0 pyrazinamide
rpsA 1834667 c.1126_1128delGCGinsTC frameshift_variant&missense_variant 1.0 pyrazinamide Uncertain significance
rpsA 1834690 c.1149T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834732 c.1191T>C synonymous_variant 0.95 pyrazinamide
rpsA 1834738 c.1197A>G synonymous_variant 0.95 pyrazinamide
rpsA 1834753 c.1212T>C synonymous_variant 0.94 pyrazinamide
rpsA 1834759 c.1218A>T synonymous_variant 0.94 pyrazinamide
rpsA 1834765 c.1224A>G synonymous_variant 0.94 pyrazinamide
rpsA 1834774 c.1233C>T synonymous_variant 0.92 pyrazinamide
rpsA 1834776 p.Ala412Glu missense_variant 0.92 pyrazinamide
rpsA 1834780 c.1239A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834786 c.1245A>G synonymous_variant 0.92 pyrazinamide
rpsA 1834789 c.1248T>C synonymous_variant 0.92 pyrazinamide
rpsA 1834792 c.1251G>C synonymous_variant 0.92 pyrazinamide
rpsA 1834811 c.1270C>A synonymous_variant 0.92 pyrazinamide
tsnR 1853361 c.-245T>C upstream_gene_variant 1.0 linezolid
tsnR 1853370 c.-236G>T upstream_gene_variant 1.0 linezolid
tsnR 1853384 c.-222G>C upstream_gene_variant 1.0 linezolid
tsnR 1853387 c.-219T>G upstream_gene_variant 1.0 linezolid
tsnR 1853390 c.-216G>C upstream_gene_variant 1.0 linezolid
tsnR 1853394 c.-212_-211delCTinsGC upstream_gene_variant 1.0 linezolid
tsnR 1853420 c.-186T>G upstream_gene_variant 1.0 linezolid
tsnR 1853432 c.-174G>C upstream_gene_variant 1.0 linezolid
tsnR 1853444 c.-162C>G upstream_gene_variant 1.0 linezolid
tsnR 1853453 c.-153G>C upstream_gene_variant 1.0 linezolid
tsnR 1853459 c.-147G>C upstream_gene_variant 1.0 linezolid
tsnR 1853462 c.-144A>G upstream_gene_variant 1.0 linezolid
tsnR 1853474 c.-132C>G upstream_gene_variant 1.0 linezolid
tsnR 1853477 c.-129T>C upstream_gene_variant 1.0 linezolid
tsnR 1853481 c.-125A>G upstream_gene_variant 0.95 linezolid
tsnR 1853489 c.-117C>T upstream_gene_variant 0.95 linezolid
tsnR 1853495 c.-111G>C upstream_gene_variant 0.94 linezolid
kasA 2517917 c.-198G>C upstream_gene_variant 0.98 isoniazid
kasA 2517941 c.-174C>G upstream_gene_variant 0.98 isoniazid
kasA 2517959 c.-156C>T upstream_gene_variant 1.0 isoniazid
kasA 2517968 c.-147T>C upstream_gene_variant 1.0 isoniazid
kasA 2517974 c.-141T>C upstream_gene_variant 1.0 isoniazid
kasA 2517989 c.-126T>C upstream_gene_variant 0.95 isoniazid
kasA 2518019 c.-96A>G upstream_gene_variant 0.9 isoniazid
kasA 2518459 c.345T>C synonymous_variant 1.0 isoniazid
kasA 2518462 c.348A>G synonymous_variant 1.0 isoniazid
kasA 2518468 c.354A>C synonymous_variant 1.0 isoniazid
kasA 2518470 p.Ala119Gly missense_variant 1.0 isoniazid
kasA 2518480 c.366T>C synonymous_variant 1.0 isoniazid
kasA 2518488 p.Ser125Thr missense_variant 1.0 isoniazid
kasA 2518496 p.Leu128Ala missense_variant 1.0 isoniazid
kasA 2518504 c.390T>C synonymous_variant 1.0 isoniazid
kasA 2518506 p.Ala131Glu missense_variant 1.0 isoniazid
kasA 2518516 c.402C>G synonymous_variant 1.0 isoniazid
kasA 2518519 c.405G>C synonymous_variant 1.0 isoniazid
kasA 2518528 c.414C>G synonymous_variant 1.0 isoniazid
kasA 2518555 c.441C>G synonymous_variant 1.0 isoniazid
kasA 2518564 c.450C>G synonymous_variant 1.0 isoniazid
kasA 2518567 c.453G>C synonymous_variant 1.0 isoniazid
kasA 2518573 c.459G>C synonymous_variant 1.0 isoniazid
kasA 2518574 p.Ile154Val missense_variant 1.0 isoniazid
kasA 2518579 c.465T>G synonymous_variant 1.0 isoniazid
kasA 2518582 c.468G>T synonymous_variant 1.0 isoniazid
kasA 2518588 c.474T>C synonymous_variant 1.0 isoniazid
kasA 2518600 c.486C>A synonymous_variant 1.0 isoniazid
kasA 2518603 c.489G>C synonymous_variant 1.0 isoniazid
kasA 2518607 c.493_495delATGinsCC frameshift_variant&missense_variant 1.0 isoniazid
kasA 2518627 c.513T>C synonymous_variant 1.0 isoniazid
kasA 2518633 c.519G>A synonymous_variant 1.0 isoniazid
kasA 2518642 c.528A>G synonymous_variant 1.0 isoniazid
kasA 2518645 c.531G>C synonymous_variant 1.0 isoniazid
kasA 2518651 c.537C>T synonymous_variant 1.0 isoniazid
kasA 2518654 p.His180Gln missense_variant 1.0 isoniazid
kasA 2518663 c.549T>G synonymous_variant 1.0 isoniazid
kasA 2519179 c.1065G>C synonymous_variant 1.0 isoniazid
kasA 2519185 c.1071C>G synonymous_variant 1.0 isoniazid
kasA 2519188 c.1074G>C synonymous_variant 1.0 isoniazid
kasA 2519194 c.1080G>C synonymous_variant 1.0 isoniazid
kasA 2519224 c.1110C>G synonymous_variant 1.0 isoniazid
kasA 2519227 c.1113G>C synonymous_variant 1.0 isoniazid
kasA 2519236 c.1122G>A synonymous_variant 1.0 isoniazid
kasA 2519239 c.1125A>C synonymous_variant 1.0 isoniazid
kasA 2519245 c.1131T>C synonymous_variant 1.0 isoniazid
kasA 2519257 c.1143C>T synonymous_variant 1.0 isoniazid
kasA 2519260 c.1146T>C synonymous_variant 1.0 isoniazid
kasA 2519263 c.1149C>T synonymous_variant 1.0 isoniazid
kasA 2519269 c.1155C>T synonymous_variant 1.0 isoniazid
kasA 2519272 c.1158C>G synonymous_variant 1.0 isoniazid
kasA 2519278 c.1164A>G synonymous_variant 1.0 isoniazid
kasA 2519281 c.1167G>T synonymous_variant 1.0 isoniazid
kasA 2519284 c.1170C>A synonymous_variant 1.0 isoniazid
kasA 2519293 c.1179T>C synonymous_variant 1.0 isoniazid
kasA 2519298 p.Arg395Gln missense_variant 1.0 isoniazid
kasA 2519305 c.1191A>C synonymous_variant 1.0 isoniazid
kasA 2519306 p.Val398Ile missense_variant 1.0 isoniazid
kasA 2519323 c.1209G>T synonymous_variant 1.0 isoniazid
kasA 2519329 c.1215C>T synonymous_variant 1.0 isoniazid
folC 2747272 c.327G>C synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747275 c.324T>C synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747281 c.318A>G synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747284 c.315G>T synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747287 c.310_312delCCGinsGC frameshift_variant&missense_variant 0.96 para-aminosalicylic_acid
folC 2747290 c.309A>G synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747299 c.300C>T synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747302 c.297A>G synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747308 c.291C>G synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747314 c.285A>G synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747317 c.282C>G synonymous_variant 0.96 para-aminosalicylic_acid
folC 2747341 c.256_258delGTCinsCG frameshift_variant&missense_variant 0.92 para-aminosalicylic_acid
folC 2747347 c.252G>T synonymous_variant 0.92 para-aminosalicylic_acid
folC 2747362 c.237G>C synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747365 c.234G>A synonymous_variant 0.89 para-aminosalicylic_acid
folC 2747371 c.228C>G synonymous_variant 0.88 para-aminosalicylic_acid
folC 2747386 c.213C>G synonymous_variant 0.9 para-aminosalicylic_acid
Rv2477c 2783037 c.1006C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783040 p.Ala335Thr missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin Uncertain significance
streptomycin Uncertain significance
levofloxacin Uncertain significance
kanamycin Uncertain significance
rifampicin Uncertain significance
amikacin Uncertain significance
Rv2477c 2783044 c.999G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783047 p.Asp332Glu missense_variant 1.0 ethambutol Uncertain significance
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Uncertain significance
amikacin
Rv2477c 2783051 p.Tyr331Phe missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783059 c.984T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783062 c.981C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783068 p.Asp325Glu missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783077 c.966T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783080 c.963G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783083 c.960G>C synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin Not assoc w R - Interim
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783086 c.957C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783092 c.951A>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783095 c.948C>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R
amikacin Not assoc w R - Interim
Rv2477c 2783098 c.945C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783101 c.942G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783116 c.927T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783140 c.903C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783149 c.894G>C synonymous_variant 1.0 ethambutol
moxifloxacin Not assoc w R - Interim
streptomycin
levofloxacin Not assoc w R - Interim
kanamycin Not assoc w R - Interim
rifampicin Not assoc w R - Interim
amikacin Not assoc w R - Interim
Rv2477c 2783158 c.885A>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783182 c.861C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783185 c.858G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783193 p.Ser284Gly missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783194 c.849A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783203 c.840C>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783215 c.828G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783218 c.825C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783224 c.819C>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783230 c.813T>G synonymous_variant 1.0 ethambutol Not assoc w R - Interim
moxifloxacin Not assoc w R - Interim
streptomycin Not assoc w R - Interim
levofloxacin Not assoc w R - Interim
kanamycin
rifampicin Not assoc w R - Interim
amikacin
Rv2477c 2783239 p.Glu268Asp missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783242 p.Thr267Lys missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783247 c.796T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783254 c.789A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783263 c.780G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783278 c.765A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783289 p.Leu252Ile missense_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783290 c.753G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783299 c.744A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783302 c.741A>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783314 c.729C>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783332 c.711T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783350 c.693T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783353 c.690T>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783359 c.684G>A synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783362 c.681G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783374 c.669G>C synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783395 c.648T>G synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
Rv2477c 2783413 c.630G>T synonymous_variant 1.0 ethambutol
moxifloxacin
streptomycin
levofloxacin
kanamycin
rifampicin
amikacin
pepQ 2859714 c.705C>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859717 c.702C>G synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859735 c.684G>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859739 p.Ala227Ser missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859765 c.654G>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859771 c.648T>C synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859774 c.645C>T synonymous_variant 1.0 clofazimine
bedaquiline
pepQ 2859778 p.Val214Ala missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859780 p.Gln213Ala missense_variant 1.0 clofazimine
bedaquiline
pepQ 2859798 c.621G>C synonymous_variant 1.0 clofazimine
bedaquiline
thyX 3067634 c.312C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067644 p.Tyr101Phe missense_variant 1.0 para-aminosalicylic_acid
thyX 3067646 c.300C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067652 c.294T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067661 c.285C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067665 p.Ile94Thr missense_variant 1.0 para-aminosalicylic_acid
thyX 3067685 c.261A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067688 c.258G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067694 c.252G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067715 c.229_231delAGCinsTCG synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067718 c.228C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067721 c.225T>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067727 c.219A>C synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067742 c.204A>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067748 c.198C>T synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067760 c.186G>A synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067763 c.183C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067770 p.Gly59Ala missense_variant 1.0 para-aminosalicylic_acid
thyX 3067781 c.165C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067787 p.Lys53Arg missense_variant 1.0 para-aminosalicylic_acid
thyX 3067790 c.156C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067796 c.150C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyX 3067799 c.147G>A synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067802 c.144C>G synonymous_variant 0.86 para-aminosalicylic_acid
thyX 3067814 c.132T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067817 c.129C>T synonymous_variant 0.91 para-aminosalicylic_acid
thyX 3067826 c.120C>A synonymous_variant 0.88 para-aminosalicylic_acid
thyX 3067838 c.108C>G synonymous_variant 0.92 para-aminosalicylic_acid
thyX 3067844 c.102G>C synonymous_variant 0.89 para-aminosalicylic_acid
thyX 3067850 c.96A>G synonymous_variant 0.89 para-aminosalicylic_acid
thyX 3067856 p.Asp30Glu missense_variant 0.89 para-aminosalicylic_acid
thyA 3073839 c.633T>C synonymous_variant 0.91 para-aminosalicylic_acid
thyA 3073863 c.609T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073887 p.Ser195Asp missense_variant 0.95 para-aminosalicylic_acid
thyA 3073892 c.580T>C synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073893 c.579C>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073902 c.570C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073925 c.547T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073929 c.543T>C synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3073953 c.519T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073956 c.516G>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3073977 c.495A>G synonymous_variant 0.95 para-aminosalicylic_acid
thyA 3073989 c.483T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3073997 c.475C>T synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074001 c.471C>G synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074004 c.468T>C synonymous_variant 0.94 para-aminosalicylic_acid
thyA 3074031 c.441T>C synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074037 c.435C>G synonymous_variant 0.97 para-aminosalicylic_acid
thyA 3074053 p.Arg140Gln missense_variant 0.97 para-aminosalicylic_acid
thyA 3074056 p.Glu139Ala missense_variant 0.96 para-aminosalicylic_acid
thyA 3074061 c.411A>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074064 c.408C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074070 c.402C>T synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074076 c.396C>G synonymous_variant 0.96 para-aminosalicylic_acid
thyA 3074082 c.390G>C synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074094 c.378G>T synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074097 c.375C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074103 c.369C>G synonymous_variant 1.0 para-aminosalicylic_acid
thyA 3074274 c.198T>C synonymous_variant 0.82 para-aminosalicylic_acid
lpqB 3624575 c.336T>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624581 c.330A>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624584 c.327G>C synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624599 c.312T>G synonymous_variant 1.0 bedaquiline
rifampicin
lpqB 3624603